melitten and scalaradial

melitten has been researched along with scalaradial* in 1 studies

Other Studies

1 other study(ies) available for melitten and scalaradial

Article	Year
Phospholipase A2 activation influences the processing and secretion of the amyloid precursor protein. Biochemical and biophysical research communications, 1993, Nov-30, Volume: 197, Issue:1 The phospholipase A2 (PLA2) inhibitors quinacrine, manoalide and scalaradial inhibit the carbachol-stimulated secretion of the amyloid precursor protein (APP) from cells transfected with the human m1 muscarinic receptor. Conversely, activation of PLA2 by melittin increases secretion of an apparently immature species of APP from these cells. These results implicate PLA2 in regulating APP processing and secretion, which may have important implications for understanding the pathogenesis of Alzheimer's Disease. Topics: Amyloid beta-Protein Precursor; Animals; Carbachol; CHO Cells; Cricetinae; Enzyme Activation; Homosteroids; Melitten; Phospholipases A; Phospholipases A2; Protein Processing, Post-Translational; Quinacrine; Receptors, Muscarinic; Sesterterpenes; Terpenes	1993

Article

Year

Phospholipase A2 activation influences the processing and secretion of the amyloid precursor protein.

Biochemical and biophysical research communications, 1993, Nov-30, Volume: 197, Issue:1

The phospholipase A2 (PLA2) inhibitors quinacrine, manoalide and scalaradial inhibit the carbachol-stimulated secretion of the amyloid precursor protein (APP) from cells transfected with the human m1 muscarinic receptor. Conversely, activation of PLA2 by melittin increases secretion of an apparently immature species of APP from these cells. These results implicate PLA2 in regulating APP processing and secretion, which may have important implications for understanding the pathogenesis of Alzheimer's Disease.

Topics: Amyloid beta-Protein Precursor; Animals; Carbachol; CHO Cells; Cricetinae; Enzyme Activation; Homosteroids; Melitten; Phospholipases A; Phospholipases A2; Protein Processing, Post-Translational; Quinacrine; Receptors, Muscarinic; Sesterterpenes; Terpenes

1993