melatonin and transforming growth factor beta

melatonin has been researched along with transforming growth factor beta in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (12.12)18.2507
2000's7 (21.21)29.6817
2010's12 (36.36)24.3611
2020's10 (30.30)2.80

Authors

AuthorsStudies
Ayettey, S; Chen, I; Cohn, CS; Duffy, L; Eck, KM; Hill, SM; Ram, PT; Reed, JC; Yuan, L1
Fujiseki, Y; Inagaki, C; Mikami, Y; Okugawa, G; Omori, K; Suzukawa, J; Uyama, M1
Ha, H; Kim, KH; Yu, MR1
Matzkin, H; Rimler, A; Zisapel, N1
Dai, J; Hill, SM; Kiefer, T; Klotz, DM; Ram, PT; Spriggs, LL; Yuan, L1
Fung, MC; Liu, F; Ng, TB1
Bizzarri, M; Borrelli, V; Cavallaro, A; Cucina, A; Stipa, F; Tagliaferri, F; Valente, MG1
Aktuğ, H; Oktem, G; Turgut, M; Uslu, S; Uysal, A; Yurtseven, ME1
Anderson, BO; Burch, JB; Cosma, G; Craven, W; Finlayson, C; Hennesey, M; Rush, A; Walling, M; Wells, RL1
Ferrebuz, A; Quiroz, Y; Rodriguez-Iturbe, B; Romero, F; Vaziri, ND1
Alonso Toldo, MP; Caetano, LC; do Prado, JC; dos Santos, CD; Frare, EO; Santello, FH1
Hao, A; Li, G; Ling, EA; Liu, S; Wang, F; Wang, J; Wang, L; Wang, Z; Yao, L; Yin, J; Zhang, X1
Becker, JU; Henze, E; Hildebrandt, A; Krüger, A; Müller, GA; Patschan, D; Patschan, S; Rinneburger, J; Wessels, JT1
Arcangeletti, M; Bartolini, D; Canonico, B; Ciffolilli, S; Galli, F; Luchetti, F; Murdolo, G; Papa, S; Piroddi, M; Reiter, RJ1
Fung, ML; Hung, MW; Lau, CF; Yeung, HM1
Akuzum, B; Choi, SI; Jeong, JB; Kim, EK; Kim, TI; Lee, E; Maeng, YS1
Glebezdina, NS; Kuklina, EM; Nekrasova, IV; Olina, AA2
Alpini, G; Ehrlich, L; Glaser, S; Lairmore, TC; Meng, F; Scrushy, M1
Aghadavod, E; Asemi, Z; Bahmani, F; Banafshe, HR; Ghaderi, A; Karimi, MA; Mansournia, MA; Mehrzad, F; Mirhosseini, N; Motmaen, M; Reiter, RJ1
Bai, C; Gao, Y; Ma, L; Yang, W; Zhang, X1
Chen, X; Guan, Y; Liu, Y; Liu, Z; Wu, Q; Zhang, W; Zhang, Y1
Chang, MC; Jeng, JH; Lee, JJ; Liao, WC; Lu, YJ; Pan, YH; Wu, HL; Yeh, CY1
Amini, P; Ashrafizadeh, M; Motevaseli, E; Najafi, M; Shirazi, A1
Go, G; Han, YS; Lee, JH; Lee, SH; Yoon, YM1
Forner, L; García-Bernal, D; García-Navarro, EM; Guerrero-Gironés, J; López-García, S; Moraleda, JM; Rodríguez-Lozano, FJ; Sanz, JL1
Aref, M; El-Malkey, NF; Emam, H; Khalil, SS1
Çetin Altındal, D; Gümüşderelioğlu, M; Jarrar, H1
Betül Tuncer, F; Boz, M; Çakıroğlu, H; Çokluk, E; Doğanay, S; Ramazan Şekeroğlu, M1
Chang, CL; Chen, CH; Chen, HH; Chiang, JY; Chu, CH; Li, YC; Yip, HK1
Abdel Moneim, AE; Al-Gebaly, AS; Al-Otaibi, AM; Al-Qahtani, WS; Albasher, G; Almeer, R1
Colares, JR; da Silva, JB; Hartmann, RM; Marroni, CA; Marroni, NP; Miguel, FM; Picada, JN; Schemitt, EG1
Benítez-King, G; Carreño-García, S; Estrada-Reyes, R; Miranda-Riestra, A; Ortiz, GG; Torres-Sanchez, ED1

Reviews

3 review(s) available for melatonin and transforming growth factor beta

ArticleYear
Melatonin regulates mesenchymal stem cell differentiation: a review.
    Journal of pineal research, 2014, Volume: 56, Issue:4

    Topics: Adipogenesis; Adipokines; Animals; Antioxidants; Cell Differentiation; Extracellular Signal-Regulated MAP Kinases; Humans; MAP Kinase Signaling System; Melatonin; Mesenchymal Stem Cells; Transforming Growth Factor beta; Wnt Proteins; Wnt Signaling Pathway

2014
Biliary epithelium: A neuroendocrine compartment in cholestatic liver disease.
    Clinics and research in hepatology and gastroenterology, 2018, Volume: 42, Issue:4

    Topics: Animals; Arginine Vasopressin; Biliary Tract; Cell Proliferation; Cholangitis; Cholestasis; Epithelial Cells; Humans; Liver; Liver Cirrhosis; Melatonin; Neovascularization, Pathologic; Neuropeptides; Neurosecretory Systems; Neurotransmitter Agents; Parasympathetic Nervous System; Renin-Angiotensin System; Sympathetic Nervous System; Transforming Growth Factor beta

2018
Melatonin: A Neurotrophic Factor?
    Molecules (Basel, Switzerland), 2022, Nov-10, Volume: 27, Issue:22

    Topics: Melatonin; Nerve Growth Factors; Pineal Gland; Sleep; Suprachiasmatic Nucleus; Transforming Growth Factor beta

2022

Trials

1 trial(s) available for melatonin and transforming growth factor beta

ArticleYear
The effects of melatonin supplementation on mental health, metabolic and genetic profiles in patients under methadone maintenance treatment.
    Addiction biology, 2019, Volume: 24, Issue:4

    Topics: Adult; Analgesics, Opioid; Antioxidants; Anxiety; Blood Glucose; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Depression; Double-Blind Method; Gene Expression; Glutathione; Humans; Insulin Resistance; Interleukin-1; Male; Malondialdehyde; Melatonin; Mental Health; Methadone; Middle Aged; Nitric Oxide; Opiate Substitution Treatment; Opioid-Related Disorders; Penile Erection; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sleep; Transforming Growth Factor beta; Triglycerides; Tumor Necrosis Factor-alpha

2019

Other Studies

29 other study(ies) available for melatonin and transforming growth factor beta

ArticleYear
A sequential treatment regimen with melatonin and all-trans retinoic acid induces apoptosis in MCF-7 tumour cells.
    British journal of cancer, 1998, Volume: 77, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Blotting, Northern; Blotting, Western; Breast Neoplasms; DNA, Neoplasm; Drug Administration Schedule; Electrophoresis; Humans; Melatonin; Neoplasms, Hormone-Dependent; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Estrogen; Transforming Growth Factor beta; Tretinoin; Tumor Cells, Cultured

1998
Natriuretic peptide receptors, NPR-A and NPR-B, in cultured rabbit retinal pigment epithelium cells.
    Japanese journal of pharmacology, 1999, Volume: 79, Issue:3

    Topics: Acetazolamide; Animals; Atrial Natriuretic Factor; Cell Division; Cells, Cultured; Dopamine; Fibroblast Growth Factor 2; Gene Expression; Growth Substances; Guanylate Cyclase; Mannitol; Melatonin; Natriuretic Peptide, C-Type; Norepinephrine; Pigment Epithelium of Eye; Platelet-Derived Growth Factor; Rabbits; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Transforming Growth Factor beta

1999
Melatonin and taurine reduce early glomerulopathy in diabetic rats.
    Free radical biology & medicine, 1999, Volume: 26, Issue:7-8

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diuresis; Fibronectins; Gene Expression Regulation; Kidney Glomerulus; Lipid Peroxidation; Male; Melatonin; Oxidative Stress; Proteinuria; Rats; Rats, Sprague-Dawley; RNA, Messenger; Taurine; Transcription, Genetic; Transforming Growth Factor beta

1999
Cross talk between melatonin and TGFbeta1 in human benign prostate epithelial cells.
    The Prostate, 1999, Sep-01, Volume: 40, Issue:4

    Topics: Blotting, Western; Dihydrotestosterone; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Humans; Male; Melatonin; Prostate; Scintillation Counting; Thymidine; Transforming Growth Factor beta

1999
Differential responsiveness of MCF-7 human breast cancer cell line stocks to the pineal hormone, melatonin.
    Journal of pineal research, 2000, Volume: 28, Issue:4

    Topics: Blotting, Northern; Breast Neoplasms; Estradiol; Female; Humans; Melatonin; Protein Biosynthesis; Proteins; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Receptors, Melatonin; Receptors, Progesterone; RNA; RNA, Messenger; Transforming Growth Factor beta; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins

2000
Pineal indoles stimulate the gene expression of immunomodulating cytokines.
    Journal of neural transmission (Vienna, Austria : 1996), 2001, Volume: 108, Issue:4

    Topics: 5-Methoxytryptamine; Adjuvants, Immunologic; Animals; Anti-Anxiety Agents; Cytokines; DNA Primers; Exudates and Transudates; Gene Expression; Indoles; Injections, Intraperitoneal; Interferon-gamma; Interleukin-1; Macrophage Colony-Stimulating Factor; Male; Melatonin; Mice; Mice, Inbred C57BL; Peritoneum; Pineal Gland; Spleen; Stem Cell Factor; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2001
Melatonin and vitamin D3 increase TGF-beta1 release and induce growth inhibition in breast cancer cell cultures.
    The Journal of surgical research, 2003, Volume: 110, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Breast Neoplasms; Cell Division; Cholecalciferol; Female; Growth Inhibitors; Melatonin; Rats; Receptors, Estrogen; Transforming Growth Factor beta; Tumor Cells, Cultured

2003
The effect of exogenous melatonin administration on trabecular width, ligament thickness and TGF-beta(1) expression in degenerated intervertebral disk tissue in the rat.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2006, Volume: 13, Issue:3

    Topics: Animals; Antioxidants; Disease Models, Animal; Gene Expression; Immunohistochemistry; Intervertebral Disc; Intervertebral Disc Displacement; Ligaments; Male; Melatonin; Random Allocation; Rats; Transforming Growth Factor beta

2006
Melatonin and estrogen in breast cyst fluids.
    Breast cancer research and treatment, 2007, Volume: 103, Issue:3

    Topics: Adult; Breast Cyst; Breast Neoplasms; Cell Line, Tumor; Cyst Fluid; Dehydroepiandrosterone Sulfate; Epidermal Growth Factor; Estradiol; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Melatonin; Middle Aged; Transforming Growth Factor beta

2007
Melatonin ameliorates oxidative stress, inflammation, proteinuria, and progression of renal damage in rats with renal mass reduction.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:2

    Topics: Actins; Animals; Blood Pressure; Cell Movement; Collagen Type IV; Creatinine; Disease Models, Animal; Hypertension; Hypertrophy; Inflammation; Kidney; Kidney Failure, Chronic; Leukocytes; Male; Malondialdehyde; Melatonin; Nephrectomy; Oxidative Stress; Proteinuria; Rats; Rats, Sprague-Dawley; Transcription Factor RelA; Transforming Growth Factor beta; Tyrosine

2008
Suppressive action of melatonin on the TH-2 immune response in rats infected with Trypanosoma cruzi.
    Journal of pineal research, 2008, Volume: 45, Issue:3

    Topics: Analysis of Variance; Animals; Chagas Disease; Concanavalin A; Cytokines; Immunity, Active; Immunity, Innate; Interleukin-10; Interleukin-4; Macrophages; Melatonin; Parasitemia; Rats; Rats, Wistar; Th1 Cells; Th2 Cells; Transforming Growth Factor beta; Trypanosoma cruzi

2008
High glucose-induced expression of inflammatory cytokines and reactive oxygen species in cultured astrocytes.
    Neuroscience, 2012, Jan-27, Volume: 202

    Topics: Animals; Astrocytes; Blotting, Western; Cell Survival; Cells, Cultured; Cytokines; Free Radical Scavengers; Glucose; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation; Interleukin-1beta; Interleukin-4; Interleukin-6; Melatonin; Mice; Mice, Inbred BALB C; NF-kappa B; Proline; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA; STAT3 Transcription Factor; Thiocarbamates; Transforming Growth Factor beta; Triterpenes; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2012
The hormone melatonin stimulates renoprotective effects of "early outgrowth" endothelial progenitor cells in acute ischemic kidney injury.
    American journal of physiology. Renal physiology, 2012, May-15, Volume: 302, Issue:10

    Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Cell Movement; Cells, Cultured; Endothelial Cells; Male; Melatonin; Mice; Mice, Inbred C57BL; Necrosis; Neovascularization, Physiologic; Recovery of Function; Reperfusion Injury; Stem Cells; Transforming Growth Factor beta

2012
Cardioprotective effects of melatonin against myocardial injuries induced by chronic intermittent hypoxia in rats.
    Journal of pineal research, 2015, Volume: 58, Issue:1

    Topics: Animals; Antioxidants; Biomarkers; Cardiotonic Agents; Chronic Disease; Cytokines; Gene Expression Regulation; Heart Diseases; Hypoxia; Male; Melatonin; Myocardium; Rats; Sleep Apnea, Obstructive; Transforming Growth Factor beta

2015
Melatonin reduces endoplasmic reticulum stress and corneal dystrophy-associated TGFBIp through activation of endoplasmic reticulum-associated protein degradation.
    Journal of pineal research, 2017, Volume: 63, Issue:3

    Topics: Antioxidants; Cell Death; Cells, Cultured; Cornea; Corneal Dystrophies, Hereditary; Drug Evaluation, Preclinical; Endoplasmic Reticulum Stress; Endoribonucleases; Extracellular Matrix Proteins; Fibroblasts; Humans; Melatonin; Protein Serine-Threonine Kinases; Proteins; Transforming Growth Factor beta; Unfolded Protein Response; X-Box Binding Protein 1

2017
Role of Endogenous Melatonin in the Regulation of Th17/Treg Balance during Pregnancy.
    Bulletin of experimental biology and medicine, 2018, Volume: 164, Issue:4

    Topics: Adult; Cell Differentiation; Female; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Immune Sera; Immunophenotyping; Interleukin-17; Melatonin; Nuclear Receptor Subfamily 1, Group F, Member 3; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Third; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Signal Transduction; T-Lymphocytes, Regulatory; Th17 Cells; Transforming Growth Factor beta

2018
Melatonin promotes self-renewal and nestin expression in neural stem cells from the retina.
    Histology and histopathology, 2019, Volume: 34, Issue:6

    Topics: Animals; Benzamides; Cell Differentiation; Cell Proliferation; Dioxoles; Extracellular Signal-Regulated MAP Kinases; Gene Expression Profiling; Indazoles; MAP Kinase Signaling System; Melatonin; Mice; Nestin; Neural Stem Cells; Piperazines; Receptor, Melatonin, MT1; Retina; RNA Interference; Smad4 Protein; Transforming Growth Factor beta

2019
Melatonin improves functional recovery in female rats after acute spinal cord injury by modulating polarization of spinal microglial/macrophages.
    Journal of neuroscience research, 2019, Volume: 97, Issue:7

    Topics: Animals; Apoptosis; Female; Interleukin-1beta; Macrophages; Melatonin; Microglia; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2019
Molecular Mechanisms of Control of Differentiation of Regulatory T-Lymphocytes by Exogenous Melatonin.
    Doklady. Biochemistry and biophysics, 2019, Volume: 484, Issue:1

    Topics: Adult; Cell Differentiation; Female; Humans; Melatonin; Nuclear Receptor Subfamily 1, Group F, Member 1; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; T-Lymphocytes, Regulatory; Transforming Growth Factor beta

2019
Stimulation of MMP-9 of oral epithelial cells by areca nut extract is related to TGF-β/Smad2-dependent and -independent pathways and prevented by betel leaf extract, hydroxychavicol and melatonin.
    Aging, 2019, 12-12, Volume: 11, Issue:23

    Topics: Areca; Arecoline; Cell Line, Tumor; Cell Survival; Epithelial Cells; Eugenol; Gene Expression Regulation; Humans; Matrix Metalloproteinase 9; Melatonin; Plant Extracts; Plant Leaves; Smad2 Protein; Transforming Growth Factor beta

2019
Mitigation of radiation-induced hematopoietic system injury by melatonin.
    Environmental toxicology, 2020, Volume: 35, Issue:8

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Male; Melatonin; Mice; Mice, Inbred C57BL; Radiation Injuries; Radiation-Protective Agents; Transforming Growth Factor beta; Whole-Body Irradiation

2020
Melatonin Protects Human Renal Proximal Tubule Epithelial Cells Against High Glucose-Mediated Fibrosis via the Cellular Prion Protein-TGF-β-Smad Signaling Axis.
    International journal of medical sciences, 2020, Volume: 17, Issue:9

    Topics: Blotting, Western; Catalase; Cell Proliferation; Collagen Type I; Fibronectins; Fibrosis; Glucose; Humans; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Melatonin; Phosphorylation; Prion Proteins; Radioimmunoprecipitation Assay; Signal Transduction; Th1 Cells; Transforming Growth Factor beta

2020
Melatonin Treatment Alters Biological and Immunomodulatory Properties of Human Dental Pulp Mesenchymal Stem Cells via Augmented Transforming Growth Factor Beta Secretion.
    Journal of endodontics, 2021, Volume: 47, Issue:3

    Topics: Cell Differentiation; Cell Proliferation; Cells, Cultured; Dental Pulp; Humans; Melatonin; Mesenchymal Stem Cells; Osteogenesis; Stem Cells; Transforming Growth Factor beta

2021
Impact of Melatonin on Full-Term Fetal Brain Development and Transforming Growth Factor-β Level in a Rat Model of Preeclampsia.
    Reproductive sciences (Thousand Oaks, Calif.), 2021, Volume: 28, Issue:8

    Topics: Animals; Brain; Disease Models, Animal; Female; Malondialdehyde; Melatonin; Oxidative Stress; Placenta Growth Factor; Pre-Eclampsia; Pregnancy; Rats; Superoxide Dismutase; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2021
Effect of melatonin/BMP-2 co-delivery scaffolds on the osteoclast activity.
    Journal of materials science. Materials in medicine, 2021, Mar-22, Volume: 32, Issue:4

    Topics: Animals; Biocompatible Materials; Bone Morphogenetic Protein 2; Bone Regeneration; Bone Resorption; Cathepsin K; Cell Differentiation; Cell Survival; Chitosan; Drug Delivery Systems; Durapatite; In Vitro Techniques; Melatonin; Mice; Microscopy, Electron, Scanning; Osteoclasts; RAW 264.7 Cells; Recombinant Proteins; Stress, Mechanical; Thermogravimetry; Tissue Scaffolds; Transforming Growth Factor beta; X-Ray Microtomography

2021
Investigation of the effect of melatonin administration on inflammatory mediators; MMP-2, TGF-β and VEGF levels in rats with sepsis.
    International journal of clinical practice, 2021, Volume: 75, Issue:11

    Topics: Animals; Disease Models, Animal; Inflammation Mediators; Matrix Metalloproteinase 2; Melatonin; Rats; Rats, Wistar; Sepsis; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A

2021
Melatonin and hyperbaric oxygen therapies suppress colorectal carcinogenesis through pleiotropic effects and multifaceted mechanisms.
    International journal of biological sciences, 2021, Volume: 17, Issue:14

    Topics: Animals; Apoptosis; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Combined Modality Therapy; Humans; Hyperbaric Oxygenation; Male; Melatonin; Mice; Mice, Inbred BALB C; Proto-Oncogene Proteins c-akt; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta

2021
Melatonin pre-treated bone marrow derived-mesenchymal stem cells prompt wound healing in rat models.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 145

    Topics: Animals; Antioxidants; Disease Models, Animal; Interleukin-1beta; Melatonin; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; NF-kappa B; Rats; Skin; Transforming Growth Factor beta; Treatment Outcome; Tumor Necrosis Factor-alpha; Wound Healing; Wounds and Injuries

2022
Melatonin Attenuates Inflammation, Oxidative Stress, and DNA Damage in Mice with Nonalcoholic Steatohepatitis Induced by a Methionine- and Choline-Deficient Diet.
    Inflammation, 2022, Volume: 45, Issue:5

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Biomarkers; Catalase; Choline; Choline Deficiency; Diet; DNA Damage; Glutathione Peroxidase; Inflammation; Liver; Melatonin; Methionine; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Nitric Oxide Synthase Type II; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Superoxide Dismutase; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2022