melatonin has been researched along with tamoxifen in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (51.43) | 18.2507 |
| 2000's | 8 (22.86) | 29.6817 |
| 2010's | 9 (25.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Anastasiadis, PG; Anninos, PA; Sandyk, R; Tsagas, N | 1 |
| Blask, DE; Hill, SM; Muraoka, H; Simon, MA; Spriggs, LL | 1 |
| Blask, DE; Lemus-Wilson, AM; Wilson, ST | 1 |
| Blask, DE; Grosso, DS; Hill, SM; Lemus-Wilson, A; Pelletier, DB; Wilson, ST; Wise, ME | 1 |
| Blask, DE; Cos, S; Hill, AB; Lemus-Wilson, A | 1 |
| Blask, DE; Cos, S | 1 |
| Barni, S; Cazzaniga, M; Esposti, D; Fossati, V; Lissoni, P; Meregalli, S; Tancini, G | 1 |
| Harrison, WA; Helton, RA; Kane, MA; Kelley, K | 1 |
| Borges, A; Kothari, A; Kothari, L | 1 |
| Abreu, P; Alonso-Solís, R; Díaz-Cruz, A; Fajardo, N; Hernández, A; Hernández, G; Hernández-Díaz, F; López-Coviella, I | 1 |
| Ardizzoia, A; Barni, S; Brivio, F; Chilelli, M; Lissoni, P; Maestroni, GJ; Paolorossi, F; Tancini, G | 1 |
| Borges, A; Ingle, A; Kothari, A; Kothari, L | 1 |
| Blask, DE; Wilson, ST; Zalatan, F | 1 |
| Harland, JD; Liburdy, RP | 1 |
| Escames, G; García, JJ; Oh, CS; Ortiz, GG; Reiter, RJ; Tang, L; Yu, BP | 1 |
| Ali-vehmas, T; Atroshi, F; Rizzo, A; Westermarck, T | 1 |
| del Rio, B; Lazo, PS; Martinez, MA; Pedrero, JG; Ramos, S; Rato, AG | 1 |
| Benane, SG; Blackman, CF; House, DE | 1 |
| Adámeková, E; Ahlers, I; Ahlersová, E; Bojková, B; Cermáková, M; Kubatka, P; M ciková-Kalická, K; Mníchová-Chamilová, M | 1 |
| Hermann, R; Jungnickel, S; Lerchl, A; Podhajsky, S | 1 |
| Anchim, T; Czeczuga-Semeniuk, E; Dabrowska, M; Dziecioł, J; Pietruczuk, M; Wołczyński, S | 1 |
| Deniz, G; Gürdöl, F; Ozden, T; Süzme, R | 1 |
| Aust, S; Baravalle, G; Ekmekcioglu, C; Jaeger, W; Klimpfinger, M; Mayer, K; Thalhammer, T | 1 |
| Haldar, C; Ortmann, O; Treeck, O | 1 |
| Acaroglu, E; Akel, I; Alanay, A; Bozkurt, G; Kocak, O; Marcucio, R | 1 |
| Ioannides, C; Papagiannidou, E; Skene, DJ | 1 |
| Anbalagan, M; Blask, DE; Brimer, S; Dauchy, RT; Frasch, T; Hauch, A; Hill, SM; Mao, L; Rowan, BG; Wren, MA; Xiang, S; Yuan, L | 1 |
| Killock, D | 1 |
| Fujinoki, M; Takei, GL | 1 |
| Akbarzadeh, M; Hamishehkar, H; Mohammadian, J; Molavi, O; Sabzichi, M; Samadi, N | 1 |
| Chen, Y; Dai, ZS; He, LJ; Huang, L; Ke, QF; Wu, JZ; Wu, WH | 1 |
2 review(s) available for melatonin and tamoxifen
| Article | Year |
|---|---|
Is the pineal gland involved in the pathogenesis of endometrial carcinoma.
Topics: Adult; Carcinoma, Endometrioid; Electromagnetic Fields; Endometrium; Female; Humans; Magnetics; Melatonin; Middle Aged; Phototherapy; Pineal Gland; Progesterone; Racial Groups; Risk Factors; Tamoxifen | 1992 |
Gonadal steroid modulation of neuroendocrine transduction: a transynaptic view.
Topics: Adrenergic Fibers; Animals; Castration; Cattle; Cell Line; Circadian Rhythm; Cyclic AMP; Epinephrine; Estradiol; Estrogen Antagonists; Estrus; Female; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Male; Melatonin; Models, Biological; Pineal Gland; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Secretory Rate; Sympatholytics; Sympathomimetics; Tamoxifen; Testosterone | 1996 |
2 trial(s) available for melatonin and tamoxifen
| Article | Year |
|---|---|
Modulation of cancer endocrine therapy by melatonin: a phase II study of tamoxifen plus melatonin in metastatic breast cancer patients progressing under tamoxifen alone.
Topics: Adult; Aged; Breast Neoplasms; Female; Humans; Insulin-Like Growth Factor I; Melatonin; Middle Aged; Neoplasm Metastasis; Tamoxifen | 1995 |
A phase II study of tamoxifen plus melatonin in metastatic solid tumour patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Melatonin; Middle Aged; Neoplasm Metastasis; Neoplasms; Tamoxifen | 1996 |
31 other study(ies) available for melatonin and tamoxifen
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
The growth inhibitory action of melatonin on human breast cancer cells is linked to the estrogen response system.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Drug Interactions; Estrogen Antagonists; Estrogens; Humans; Melatonin; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured | 1992 |
Melatonin augments the sensitivity of MCF-7 human breast cancer cells to tamoxifen in vitro.
Topics: Breast Neoplasms; Cell Division; Drug Synergism; Humans; Melatonin; Tamoxifen; Tumor Cells, Cultured | 1992 |
Pineal melatonin inhibition of tumor promotion in the N-nitroso-N-methylurea model of mammary carcinogenesis: potential involvement of antiestrogenic mechanisms in vivo.
Topics: Animals; Disease Models, Animal; Estradiol; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Mice; Neoplasm Recurrence, Local; Ovariectomy; Pineal Gland; Prolactin; Radioimmunoassay; Receptors, Estrogen; Tamoxifen | 1991 |
Effects of melatonin on the cell cycle kinetics and "estrogen-rescue" of MCF-7 human breast cancer cells in culture.
Topics: Cell Cycle; Cell Division; Estradiol; Estrogens; Flow Cytometry; Humans; Melatonin; Tamoxifen; Tumor Cells, Cultured | 1991 |
Effects of the pineal hormone melatonin on the anchorage-independent growth of human breast cancer cells (MCF-7) in a clonogenic culture system.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Adhesion; Cell Division; Culture Media; Depression, Chemical; Dose-Response Relationship, Drug; Female; Humans; Melatonin; Pineal Gland; Tamoxifen; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1990 |
Melatonin interactions with cultured murine B16 melanoma cells.
Topics: Animals; Biological Transport; Cell Division; Estradiol; Humans; Melanoma; Melanoma, Experimental; Melatonin; Mice; Neoplasm Proteins; Receptors, Cell Surface; Receptors, Melatonin; Tamoxifen; Tumor Cells, Cultured | 1993 |
Chemoprevention by melatonin and combined melatonin-tamoxifen therapy of second generation nitroso-methylurea-induced mammary tumours in rats.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Chemoprevention; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Synergism; Estrogen Antagonists; Female; Mammary Neoplasms, Animal; Melatonin; Methylnitrosourea; Neoplasms, Second Primary; Pharmaceutical Vehicles; Rats; Rats, Sprague-Dawley; Tamoxifen | 1995 |
Combination of melatonin and tamoxifen as a chemoprophylaxis against N-nitroso-N-methylurea-induced rat mammary tumors.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen | 1997 |
Physiological melatonin inhibition of human breast cancer cell growth in vitro: evidence for a glutathione-mediated pathway.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Breast Neoplasms; Buthionine Sulfoximine; Cell Division; Diuretics; Ethacrynic Acid; Female; Glutathione; Humans; Melatonin; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured | 1997 |
Environmental magnetic fields inhibit the antiproliferative action of tamoxifen and melatonin in a human breast cancer cell line.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Dose-Response Relationship, Radiation; Electromagnetic Fields; Environmental Exposure; Female; Growth Inhibitors; Humans; Melatonin; Tamoxifen; Tumor Cells, Cultured | 1997 |
Melatonin enhances tamoxifen's ability to prevent the reduction in microsomal membrane fluidity induced by lipid peroxidation.
Topics: Animals; Antioxidants; Drug Synergism; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Membrane Fluidity; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Tamoxifen | 1998 |
Effects of tamoxifen, melatonin, coenzyme Q10, and L-carnitine supplementation on bacterial growth in the presence of mycotoxins.
Topics: Aflatoxin B1; Antineoplastic Agents, Hormonal; Antioxidants; Bacteria; Carboxylic Acids; Carnitine; Cell Division; Coenzymes; Dose-Response Relationship, Drug; Erysipelothrix; Escherichia coli; Fumonisins; Lacticaseibacillus casei; Lactobacillus; Melatonin; Mycotoxins; Ochratoxins; Salmonella; Staphylococcus aureus; Streptococcus agalactiae; T-2 Toxin; Tamoxifen; Trichothecenes; Ubiquinone; Yersinia enterocolitica | 1998 |
Complementary treatments highlighted at recent meeting.
Topics: Breast Neoplasms; Coenzymes; Drug Therapy, Combination; Female; Humans; Melatonin; Receptors, Estrogen; Soybean Proteins; Tamoxifen; Ubiquinone | 1999 |
Melatonin blocks the activation of estrogen receptor for DNA binding.
Topics: Base Sequence; Binding Sites; Biological Transport, Active; Breast Neoplasms; Cell Division; Cell Nucleus; DNA, Neoplasm; Estradiol; Estrogen Antagonists; Female; Gene Expression; Humans; Melatonin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Receptors, Melatonin; Recombinant Proteins; Tamoxifen; Transfection; Tumor Cells, Cultured | 1999 |
The influence of 1.2 microT, 60 Hz magnetic fields on melatonin- and tamoxifen-induced inhibition of MCF-7 cell growth.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Female; Humans; Magnetics; Melatonin; Tamoxifen; Tumor Cells, Cultured | 2001 |
Effects of tamoxifen and melatonin on mammary gland cancer induced by N-methyl-N-nitrosourea and by 7,12-dimethylbenz(a)anthracene, respectively, in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Estrogen Receptor Modulators; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen | 2001 |
Potentiation of antiproliferative effects of tamoxifen and ethanol on mouse hepatoma cells by melatonin: possible involvement of mitogen-activated protein kinase and induction of apoptosis.
Topics: Animals; Antineoplastic Agents, Hormonal; Apoptosis; Carcinoma, Hepatocellular; Cell Division; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Liver Neoplasms; Melatonin; Mice; Mitogen-Activated Protein Kinase Kinases; Molecular Biology; Phosphorylation; Tamoxifen; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Effect of melatonin and all-trans retinoic acid on the proliferation and induction of the apoptotic pathway in the culture of human breast cancer cell line MCF-7.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Count; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Estradiol; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Melatonin; Necrosis; Proliferating Cell Nuclear Antigen; Tamoxifen; Tretinoin; Tumor Cells, Cultured | 2002 |
Response in DNA ploidy of hepatocytes to tamoxifen and/or melatonin in vivo.
Topics: Aneuploidy; Animals; Antineoplastic Agents, Hormonal; Antioxidants; Chemical and Drug Induced Liver Injury; Female; Flow Cytometry; Melatonin; Ploidies; Rats; Rats, Wistar; Tamoxifen | 2001 |
Biotransformation of melatonin in human breast cancer cell lines: role of sulfotransferase 1A1.
Topics: Antineoplastic Agents, Hormonal; Arylsulfotransferase; Biotransformation; Breast Neoplasms; Cell Line, Tumor; Cytosol; Female; Humans; Melatonin; RNA, Messenger; Tamoxifen; Transfection | 2005 |
Antiestrogens modulate MT1 melatonin receptor expression in breast and ovarian cancer cell lines.
Topics: Breast Neoplasms; Cell Line, Tumor; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Melatonin; Ovarian Neoplasms; Receptor, Melatonin, MT1; Signal Transduction; Tamoxifen; Up-Regulation | 2006 |
The effect of calmodulin antagonists on experimental scoliosis: a pinealectomized chicken model.
Topics: Animals; Bone Density Conservation Agents; Calmodulin; Chickens; Disease Models, Animal; Dopamine Antagonists; Female; Melatonin; Pineal Gland; Radiography; Scoliosis; Severity of Illness Index; Tamoxifen; Triflupromazine | 2009 |
Potential drug interactions with melatonin.
Topics: 5-Methoxypsoralen; Acetaminophen; Analgesics, Non-Narcotic; Animals; Antidepressive Agents, Second-Generation; Antineoplastic Agents, Hormonal; Central Nervous System Depressants; Diazepam; Drug Interactions; Estrogens; Fluvoxamine; Humans; Hypnotics and Sedatives; Male; Melatonin; Methoxsalen; Microsomes, Liver; Middle Aged; Rats, Wistar; Tamoxifen | 2014 |
Circadian and melatonin disruption by exposure to light at night drives intrinsic resistance to tamoxifen therapy in breast cancer.
Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Circadian Rhythm; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Humans; Light; MCF-7 Cells; Melatonin; Mice, Nude; Random Allocation; Rats; Tamoxifen; Xenograft Model Antitumor Assays | 2014 |
Drug therapy: keeping rats in the dark sheds light on tamoxifen resistance.
Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Circadian Rhythm; Female; Humans; Light; Melatonin; Tamoxifen | 2014 |
Estrogen suppresses melatonin-enhanced hyperactivation of hamster spermatozoa.
Topics: Animals; Estradiol; Estrogen Antagonists; Female; gamma-Aminobutyric Acid; Kinetics; Male; Melatonin; Mesocricetus; Models, Biological; Sperm Capacitation; Sperm Motility; Spermatozoa; Tamoxifen | 2015 |
Sustained release of melatonin: A novel approach in elevating efficacy of tamoxifen in breast cancer treatment.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Drug Carriers; Female; Humans; MCF-7 Cells; Melatonin; Tamoxifen | 2016 |
Effect of Melatonin and Calmodulin in an Idiopathic Scoliosis Model.
Topics: Animals; Calmodulin; Disease Models, Animal; Female; Humans; Lighting; Melatonin; Rats; Scoliosis; Tamoxifen; Tryptamines | 2016 |