melatonin and tamoxifen

melatonin has been researched along with tamoxifen in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's18 (51.43)18.2507
2000's8 (22.86)29.6817
2010's9 (25.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Anastasiadis, PG; Anninos, PA; Sandyk, R; Tsagas, N1
Blask, DE; Hill, SM; Muraoka, H; Simon, MA; Spriggs, LL1
Blask, DE; Lemus-Wilson, AM; Wilson, ST1
Blask, DE; Grosso, DS; Hill, SM; Lemus-Wilson, A; Pelletier, DB; Wilson, ST; Wise, ME1
Blask, DE; Cos, S; Hill, AB; Lemus-Wilson, A1
Blask, DE; Cos, S1
Barni, S; Cazzaniga, M; Esposti, D; Fossati, V; Lissoni, P; Meregalli, S; Tancini, G1
Harrison, WA; Helton, RA; Kane, MA; Kelley, K1
Borges, A; Kothari, A; Kothari, L1
Abreu, P; Alonso-Solís, R; Díaz-Cruz, A; Fajardo, N; Hernández, A; Hernández, G; Hernández-Díaz, F; López-Coviella, I1
Ardizzoia, A; Barni, S; Brivio, F; Chilelli, M; Lissoni, P; Maestroni, GJ; Paolorossi, F; Tancini, G1
Borges, A; Ingle, A; Kothari, A; Kothari, L1
Blask, DE; Wilson, ST; Zalatan, F1
Harland, JD; Liburdy, RP1
Escames, G; García, JJ; Oh, CS; Ortiz, GG; Reiter, RJ; Tang, L; Yu, BP1
Ali-vehmas, T; Atroshi, F; Rizzo, A; Westermarck, T1
del Rio, B; Lazo, PS; Martinez, MA; Pedrero, JG; Ramos, S; Rato, AG1
Benane, SG; Blackman, CF; House, DE1
Adámeková, E; Ahlers, I; Ahlersová, E; Bojková, B; Cermáková, M; Kubatka, P; M ciková-Kalická, K; Mníchová-Chamilová, M1
Hermann, R; Jungnickel, S; Lerchl, A; Podhajsky, S1
Anchim, T; Czeczuga-Semeniuk, E; Dabrowska, M; Dziecioł, J; Pietruczuk, M; Wołczyński, S1
Deniz, G; Gürdöl, F; Ozden, T; Süzme, R1
Aust, S; Baravalle, G; Ekmekcioglu, C; Jaeger, W; Klimpfinger, M; Mayer, K; Thalhammer, T1
Haldar, C; Ortmann, O; Treeck, O1
Acaroglu, E; Akel, I; Alanay, A; Bozkurt, G; Kocak, O; Marcucio, R1
Ioannides, C; Papagiannidou, E; Skene, DJ1
Anbalagan, M; Blask, DE; Brimer, S; Dauchy, RT; Frasch, T; Hauch, A; Hill, SM; Mao, L; Rowan, BG; Wren, MA; Xiang, S; Yuan, L1
Killock, D1
Fujinoki, M; Takei, GL1
Akbarzadeh, M; Hamishehkar, H; Mohammadian, J; Molavi, O; Sabzichi, M; Samadi, N1
Chen, Y; Dai, ZS; He, LJ; Huang, L; Ke, QF; Wu, JZ; Wu, WH1

Reviews

2 review(s) available for melatonin and tamoxifen

ArticleYear
Is the pineal gland involved in the pathogenesis of endometrial carcinoma.
    The International journal of neuroscience, 1992, Volume: 62, Issue:1-2

    Topics: Adult; Carcinoma, Endometrioid; Electromagnetic Fields; Endometrium; Female; Humans; Magnetics; Melatonin; Middle Aged; Phototherapy; Pineal Gland; Progesterone; Racial Groups; Risk Factors; Tamoxifen

1992
Gonadal steroid modulation of neuroendocrine transduction: a transynaptic view.
    Cellular and molecular neurobiology, 1996, Volume: 16, Issue:3

    Topics: Adrenergic Fibers; Animals; Castration; Cattle; Cell Line; Circadian Rhythm; Cyclic AMP; Epinephrine; Estradiol; Estrogen Antagonists; Estrus; Female; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Male; Melatonin; Models, Biological; Pineal Gland; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Secretory Rate; Sympatholytics; Sympathomimetics; Tamoxifen; Testosterone

1996

Trials

2 trial(s) available for melatonin and tamoxifen

ArticleYear
Modulation of cancer endocrine therapy by melatonin: a phase II study of tamoxifen plus melatonin in metastatic breast cancer patients progressing under tamoxifen alone.
    British journal of cancer, 1995, Volume: 71, Issue:4

    Topics: Adult; Aged; Breast Neoplasms; Female; Humans; Insulin-Like Growth Factor I; Melatonin; Middle Aged; Neoplasm Metastasis; Tamoxifen

1995
A phase II study of tamoxifen plus melatonin in metastatic solid tumour patients.
    British journal of cancer, 1996, Volume: 74, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Melatonin; Middle Aged; Neoplasm Metastasis; Neoplasms; Tamoxifen

1996

Other Studies

31 other study(ies) available for melatonin and tamoxifen

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The growth inhibitory action of melatonin on human breast cancer cells is linked to the estrogen response system.
    Cancer letters, 1992, Jul-10, Volume: 64, Issue:3

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Drug Interactions; Estrogen Antagonists; Estrogens; Humans; Melatonin; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured

1992
Melatonin augments the sensitivity of MCF-7 human breast cancer cells to tamoxifen in vitro.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 75, Issue:2

    Topics: Breast Neoplasms; Cell Division; Drug Synergism; Humans; Melatonin; Tamoxifen; Tumor Cells, Cultured

1992
Pineal melatonin inhibition of tumor promotion in the N-nitroso-N-methylurea model of mammary carcinogenesis: potential involvement of antiestrogenic mechanisms in vivo.
    Journal of cancer research and clinical oncology, 1991, Volume: 117, Issue:6

    Topics: Animals; Disease Models, Animal; Estradiol; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Mice; Neoplasm Recurrence, Local; Ovariectomy; Pineal Gland; Prolactin; Radioimmunoassay; Receptors, Estrogen; Tamoxifen

1991
Effects of melatonin on the cell cycle kinetics and "estrogen-rescue" of MCF-7 human breast cancer cells in culture.
    Journal of pineal research, 1991, Volume: 10, Issue:1

    Topics: Cell Cycle; Cell Division; Estradiol; Estrogens; Flow Cytometry; Humans; Melatonin; Tamoxifen; Tumor Cells, Cultured

1991
Effects of the pineal hormone melatonin on the anchorage-independent growth of human breast cancer cells (MCF-7) in a clonogenic culture system.
    Cancer letters, 1990, Apr-20, Volume: 50, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Adhesion; Cell Division; Culture Media; Depression, Chemical; Dose-Response Relationship, Drug; Female; Humans; Melatonin; Pineal Gland; Tamoxifen; Tumor Cells, Cultured; Tumor Stem Cell Assay

1990
Melatonin interactions with cultured murine B16 melanoma cells.
    Melanoma research, 1993, Volume: 3, Issue:6

    Topics: Animals; Biological Transport; Cell Division; Estradiol; Humans; Melanoma; Melanoma, Experimental; Melatonin; Mice; Neoplasm Proteins; Receptors, Cell Surface; Receptors, Melatonin; Tamoxifen; Tumor Cells, Cultured

1993
Chemoprevention by melatonin and combined melatonin-tamoxifen therapy of second generation nitroso-methylurea-induced mammary tumours in rats.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1995, Volume: 4, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Chemoprevention; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Synergism; Estrogen Antagonists; Female; Mammary Neoplasms, Animal; Melatonin; Methylnitrosourea; Neoplasms, Second Primary; Pharmaceutical Vehicles; Rats; Rats, Sprague-Dawley; Tamoxifen

1995
Combination of melatonin and tamoxifen as a chemoprophylaxis against N-nitroso-N-methylurea-induced rat mammary tumors.
    Cancer letters, 1997, Jan-01, Volume: 111, Issue:1-2

    Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen

1997
Physiological melatonin inhibition of human breast cancer cell growth in vitro: evidence for a glutathione-mediated pathway.
    Cancer research, 1997, May-15, Volume: 57, Issue:10

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Breast Neoplasms; Buthionine Sulfoximine; Cell Division; Diuretics; Ethacrynic Acid; Female; Glutathione; Humans; Melatonin; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured

1997
Environmental magnetic fields inhibit the antiproliferative action of tamoxifen and melatonin in a human breast cancer cell line.
    Bioelectromagnetics, 1997, Volume: 18, Issue:8

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Dose-Response Relationship, Radiation; Electromagnetic Fields; Environmental Exposure; Female; Growth Inhibitors; Humans; Melatonin; Tamoxifen; Tumor Cells, Cultured

1997
Melatonin enhances tamoxifen's ability to prevent the reduction in microsomal membrane fluidity induced by lipid peroxidation.
    The Journal of membrane biology, 1998, Mar-01, Volume: 162, Issue:1

    Topics: Animals; Antioxidants; Drug Synergism; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Membrane Fluidity; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Tamoxifen

1998
Effects of tamoxifen, melatonin, coenzyme Q10, and L-carnitine supplementation on bacterial growth in the presence of mycotoxins.
    Pharmacological research, 1998, Volume: 38, Issue:4

    Topics: Aflatoxin B1; Antineoplastic Agents, Hormonal; Antioxidants; Bacteria; Carboxylic Acids; Carnitine; Cell Division; Coenzymes; Dose-Response Relationship, Drug; Erysipelothrix; Escherichia coli; Fumonisins; Lacticaseibacillus casei; Lactobacillus; Melatonin; Mycotoxins; Ochratoxins; Salmonella; Staphylococcus aureus; Streptococcus agalactiae; T-2 Toxin; Tamoxifen; Trichothecenes; Ubiquinone; Yersinia enterocolitica

1998
Complementary treatments highlighted at recent meeting.
    Oncology (Williston Park, N.Y.), 1999, Volume: 13, Issue:2

    Topics: Breast Neoplasms; Coenzymes; Drug Therapy, Combination; Female; Humans; Melatonin; Receptors, Estrogen; Soybean Proteins; Tamoxifen; Ubiquinone

1999
Melatonin blocks the activation of estrogen receptor for DNA binding.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:8

    Topics: Base Sequence; Binding Sites; Biological Transport, Active; Breast Neoplasms; Cell Division; Cell Nucleus; DNA, Neoplasm; Estradiol; Estrogen Antagonists; Female; Gene Expression; Humans; Melatonin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Receptors, Melatonin; Recombinant Proteins; Tamoxifen; Transfection; Tumor Cells, Cultured

1999
The influence of 1.2 microT, 60 Hz magnetic fields on melatonin- and tamoxifen-induced inhibition of MCF-7 cell growth.
    Bioelectromagnetics, 2001, Volume: 22, Issue:2

    Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Female; Humans; Magnetics; Melatonin; Tamoxifen; Tumor Cells, Cultured

2001
Effects of tamoxifen and melatonin on mammary gland cancer induced by N-methyl-N-nitrosourea and by 7,12-dimethylbenz(a)anthracene, respectively, in female Sprague-Dawley rats.
    Folia biologica, 2001, Volume: 47, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Estrogen Receptor Modulators; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen

2001
Potentiation of antiproliferative effects of tamoxifen and ethanol on mouse hepatoma cells by melatonin: possible involvement of mitogen-activated protein kinase and induction of apoptosis.
    Journal of pineal research, 2002, Volume: 33, Issue:1

    Topics: Animals; Antineoplastic Agents, Hormonal; Apoptosis; Carcinoma, Hepatocellular; Cell Division; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Liver Neoplasms; Melatonin; Mice; Mitogen-Activated Protein Kinase Kinases; Molecular Biology; Phosphorylation; Tamoxifen; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

2002
Effect of melatonin and all-trans retinoic acid on the proliferation and induction of the apoptotic pathway in the culture of human breast cancer cell line MCF-7.
    Polish journal of pathology : official journal of the Polish Society of Pathologists, 2002, Volume: 53, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Count; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Estradiol; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Melatonin; Necrosis; Proliferating Cell Nuclear Antigen; Tamoxifen; Tretinoin; Tumor Cells, Cultured

2002
Response in DNA ploidy of hepatocytes to tamoxifen and/or melatonin in vivo.
    Research communications in molecular pathology and pharmacology, 2001, Volume: 109, Issue:5-6

    Topics: Aneuploidy; Animals; Antineoplastic Agents, Hormonal; Antioxidants; Chemical and Drug Induced Liver Injury; Female; Flow Cytometry; Melatonin; Ploidies; Rats; Rats, Wistar; Tamoxifen

2001
Biotransformation of melatonin in human breast cancer cell lines: role of sulfotransferase 1A1.
    Journal of pineal research, 2005, Volume: 39, Issue:3

    Topics: Antineoplastic Agents, Hormonal; Arylsulfotransferase; Biotransformation; Breast Neoplasms; Cell Line, Tumor; Cytosol; Female; Humans; Melatonin; RNA, Messenger; Tamoxifen; Transfection

2005
Antiestrogens modulate MT1 melatonin receptor expression in breast and ovarian cancer cell lines.
    Oncology reports, 2006, Volume: 15, Issue:1

    Topics: Breast Neoplasms; Cell Line, Tumor; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Melatonin; Ovarian Neoplasms; Receptor, Melatonin, MT1; Signal Transduction; Tamoxifen; Up-Regulation

2006
The effect of calmodulin antagonists on experimental scoliosis: a pinealectomized chicken model.
    Spine, 2009, Mar-15, Volume: 34, Issue:6

    Topics: Animals; Bone Density Conservation Agents; Calmodulin; Chickens; Disease Models, Animal; Dopamine Antagonists; Female; Melatonin; Pineal Gland; Radiography; Scoliosis; Severity of Illness Index; Tamoxifen; Triflupromazine

2009
Potential drug interactions with melatonin.
    Physiology & behavior, 2014, May-28, Volume: 131

    Topics: 5-Methoxypsoralen; Acetaminophen; Analgesics, Non-Narcotic; Animals; Antidepressive Agents, Second-Generation; Antineoplastic Agents, Hormonal; Central Nervous System Depressants; Diazepam; Drug Interactions; Estrogens; Fluvoxamine; Humans; Hypnotics and Sedatives; Male; Melatonin; Methoxsalen; Microsomes, Liver; Middle Aged; Rats, Wistar; Tamoxifen

2014
Circadian and melatonin disruption by exposure to light at night drives intrinsic resistance to tamoxifen therapy in breast cancer.
    Cancer research, 2014, Aug-01, Volume: 74, Issue:15

    Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Circadian Rhythm; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Humans; Light; MCF-7 Cells; Melatonin; Mice, Nude; Random Allocation; Rats; Tamoxifen; Xenograft Model Antitumor Assays

2014
Drug therapy: keeping rats in the dark sheds light on tamoxifen resistance.
    Nature reviews. Clinical oncology, 2014, Volume: 11, Issue:9

    Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Circadian Rhythm; Female; Humans; Light; Melatonin; Tamoxifen

2014
Estrogen suppresses melatonin-enhanced hyperactivation of hamster spermatozoa.
    The Journal of reproduction and development, 2015, Volume: 61, Issue:4

    Topics: Animals; Estradiol; Estrogen Antagonists; Female; gamma-Aminobutyric Acid; Kinetics; Male; Melatonin; Mesocricetus; Models, Biological; Sperm Capacitation; Sperm Motility; Spermatozoa; Tamoxifen

2015
Sustained release of melatonin: A novel approach in elevating efficacy of tamoxifen in breast cancer treatment.
    Colloids and surfaces. B, Biointerfaces, 2016, Sep-01, Volume: 145

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Drug Carriers; Female; Humans; MCF-7 Cells; Melatonin; Tamoxifen

2016
Effect of Melatonin and Calmodulin in an Idiopathic Scoliosis Model.
    BioMed research international, 2016, Volume: 2016

    Topics: Animals; Calmodulin; Disease Models, Animal; Female; Humans; Lighting; Melatonin; Rats; Scoliosis; Tamoxifen; Tryptamines

2016