melatonin has been researched along with ramelteon in 86 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 24 (27.91) | 29.6817 |
2010's | 41 (47.67) | 24.3611 |
2020's | 21 (24.42) | 2.80 |
Authors | Studies |
---|---|
Fukatsu, K; Hinuma, S; Hirai, K; Imai, Y; Kato, K; Kawada, M; Matsumoto, K; Miyamoto, M; Nishikawa, H; Ohkawa, S; Tokunoh, R; Uchikawa, O | 1 |
Chandrasena, G; Doller, D; Jiang, Y; Keim, H; Li, G; Poda, SB; Ren, Y; Topiol, SW; Zhou, H | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Cecon, E; Jockers, R; Rivara, S; Witt-Enderby, PA; Zlotos, DP | 1 |
Kimura, H; Miyamoto, M; Nishikawa, H; Ohkawa, S; Yoshikubo, S; Yukuhiro, N | 1 |
Gillette, MU; Turek, FW | 1 |
Doken, Y; Hirai, K; Miyamoto, M; Nishikawa, H; Ohkawa, S; Uchikawa, O | 1 |
Cardinali, DP; Pandi-Perumal, SR; Srinivasan, V; Zisapel, N | 1 |
Erman, M; Sainati, S; Seiden, D; Zammit, G; Zhang, J | 1 |
Wurtman, R | 1 |
Bellon, A | 1 |
Steinhilber, D | 1 |
Davidson, K; Eleutheriades, A; Sugden, D; Tsotinis, A | 1 |
Pulisetty, S; Tariq, SH | 1 |
Miyamoto, M | 1 |
Davidson, K; Fisher, SP; Kulla, A; Sugden, D | 1 |
Cardinali, DP; Hardeland, R; Pandi-Perumal, SR; Poeggeler, B; Srinivasan, V; Trakht, I | 1 |
Cardinali, DP; Hardeland, R; Pandi-Perumal, SR; Poeggeler, B; Spence, DW; Srinivasan, V; Trakht, I | 1 |
Arendt, J; Rajaratnam, SM | 1 |
Peng, X; Richardson, GS; Rodriguez, L; Wang-Weigand, S; Zee, PC | 1 |
Cardinali, DP; Golombek, DA | 1 |
Richardson, GS; Wang-Weigand, S; Zammit, G; Zhang, J | 1 |
Cardinali, DP; Hardeland, R; Pandi-Perumal, SR; Poeggeler, B; Spence, DW; Srinivasan, V; Trahkt, I | 1 |
Cespuglio, R; Delagrange, P; Descamps, A; Millan, M; Millan, MJ; Rousset, C; Spedding, M | 1 |
Hirai, K; Nishiyama, K; Shintani, Y; Yoshikubo, S | 1 |
Brown, GM; Cardinali, DP; Hardeland, R; Moscovitch, A; Pandi-Perumal, SR; Spence, DW; Srinivasan, V | 1 |
Prendergast, BJ | 1 |
Dawson, D; Ferguson, SA; Rajaratnam, SM | 1 |
Peng, X; Roth, T; Wang-Weigand, S; Wright, KP; Zee, PC | 1 |
Fonteles, MM; Macedo, D; Rios, ER; Rocha, NF; Sousa, FC; Vasconcelos, S; Venâncio, ET; Woods, DJ | 1 |
Brown, GM; Cardinali, DP; Pandi-Perumal, SR; Singh, J; Spence, DW; Srinivasan, V | 1 |
Dubocovich, ML; Hudson, RL; Rawashdeh, O; Stepien, I | 1 |
Brown, GM; Brzezinski, A; Cardinali, DP; Pandi-Perumal, SR; Spence, DW; Srinivasan, V | 1 |
Carazo, A; Casado, J; de la Cueva, P; León, J; Maté, A; Muñoz de Rueda, P; Quiles, R; Ruíz, S; Ruíz-Extremera, A; Salmerón, J; Sanjuán, L | 1 |
Brown, GM; Brzezinski, A; Cardinali, DP; Srinivasan, V | 1 |
Bellantuono, C; Catena-Dell'Osso, M; Marazziti, D; Rotella, F | 1 |
Brown, GM; Brzezinski, A; Othaman, Z; Prasad, A; Srinivasan, V; Zakaria, R | 1 |
Ito, T | 1 |
Hardeland, R; Poeggeler, B | 1 |
Baño Otalora, B; Bonet-Costa, V; Camello, PJ; Gambini, J; Madrid, JA; Popovic, M; Popovic, N; Reiter, RJ; Rol, MÁ; Viña, J | 1 |
Aritake, S; Enomoto, M; Hida, A; Higuchi, S; Kamei, Y; Katayose, Y; Kitamura, S; Mishima, K; Moriguchi, Y; Nozaki, K; Watanabe, M | 1 |
Furuya, M; Horiguchi, J; Miyaoka, T; Otsuka, S; Tanaka, I; Wake, R; Yamashita, S; Yasuda, H | 1 |
Inagaki, K; Iwasaki, Y; Makino, H; Nakamura, E; Ogura-Ochi, K; Otsuka, F; Terasaka, T; Toma, K; Tsukamoto, N | 1 |
Fink, T; Glas, M; Kiefer, D; Kleber, A; Mathes, AM; Rensing, H; Reus, E; Volk, T; Wolf, A; Wolf, B; Wolff, M | 1 |
Araki, A; Cho, K; Fukuda, I; Miyamoto, A; Oka, R; Tanaka, H | 1 |
Cohen, DA; McCleery, J; Sharpley, AL | 2 |
Chakraborti, D; Tampi, DJ; Tampi, RR | 1 |
Cai, C; Gao, C; Guan, JH; Guo, J; Huang, YL; Liang, XB; Qian, LQ; Zhao, GP | 1 |
Frydman-Marom, A; Laudon, M | 1 |
Fukumizu, M; Hayashi, M; Ishizaki, A; Kohyama, J; Miyajima, T; Tanaka, H | 1 |
Bellivier, F; Etain, B; Franchi, JA; Geoffroy, PA; Ritter, P | 1 |
Abdallah, GT; Mo, Y; Scheer, CE | 1 |
Abend, M; Fink, T; Glas, M; Kleber, A; Mathes, AM; Ruf, CG; Volk, T; Wolf, A; Wolf, B | 1 |
Chen, S; Desislava, D; Liang, F; Shi, L; Wu, Q; Xu, L; Zhang, J | 1 |
Abrahamsson, KE; Cooper, JM; Gamble, KL; Hablitz, LM; Molzof, HE; Prosser, RA | 1 |
Bahk, WM; Wang, HR; Woo, YS | 1 |
Alagiakrishnan, K | 1 |
Gales, MA; Walker, CK | 1 |
He, ZY; Liang, JP; Song, ZC; Zhang, X; Zhou, W; Zhu, CL | 1 |
Fazzari, M; James, SA; Lam, S; Pinkhasov, A; Singh, D | 1 |
Batyuk, A; Cherezov, V; Gati, C; Grandner, JM; Han, GW; Hao, S; Huang, XP; Johansson, LC; Katritch, V; Li, C; Liu, W; McCorvy, JD; Olsen, RHJ; Patel, N; Roth, BL; Slocum, ST; Stauch, B; Stevens, RC; Tribo, AR; Weierstall, U; Yous, S; Zaare, S; Zatsepin, NA; Zhu, L | 1 |
Batyuk, A; Brehm, W; Cherezov, V; Gati, C; Grandner, JM; Grant, TD; Han, GW; Huang, XP; Ishchenko, A; Johansson, LC; Katritch, V; Liu, W; Madsen, C; McCorvy, JD; Michaelian, N; Olsen, RHJ; Patel, N; Roth, BL; Shiriaeva, A; Slocum, ST; Stauch, B; Stevens, RC; Tribo, AR; Weierstall, U; White, TA; Yous, S; Zhu, L | 1 |
Gao, F; Li, Z; Sun, W; Zhang, Q; Zhang, S | 1 |
Khor, AJ; Ng, KT; Teoh, WY | 1 |
Pei-Chen Chang, J; Satyanarayanan, SK; Su, H; Su, KP; Tseng, PT; Yang, CP | 1 |
Jena, M; Maiti, R; Mishra, A; Mishra, BR; Nath, S; Sahu, P | 1 |
Cubała, WJ; Lewandowska, K; Małkiewicz, MA; Mędrzycka-Dąbrowska, WA; Siemiński, M; Winklewski, PJ | 1 |
Chen, Z; Fu, W; Han, Y; Li, J; Li, X; Qin, Z; Sha, T; Sun, M; Wang, W; Wu, J; Zeng, Z; Zhao, B | 1 |
Aydın, A; Gürbüz, MA; Halıcı, Z; Karaman, A; Köse, A; Köse, D; Toktay, E; Ugan, RA | 1 |
McCleery, J; Sharpley, AL | 1 |
DeGrado, JR; Dube, KM; Lupi, KE; Romero, N | 1 |
Bomsel, M; Cecon, E; Dam, J; Ghigna, MR; Izabelle, C; Jockers, R; Klonjkowski, B; Poder, SL; Real, F; Tu, L; Zhu, A | 1 |
Hashimoto, T; Kataoka, Y; Matsumoto, M; Suzuki, T; Tsunemitsu, T | 1 |
Jiang, YJ; Liu, J; Wang, YH; Wang, YQ; Zhao, HQ; Zou, MS | 1 |
Du, Y; Gong, Q; Guo, Q; Li, X; Liu, Z; Lu, Q; Tao, Y; Teng, M; Wang, Q | 1 |
Kawilapat, S; Kongsaengdao, S; Likhitsathian, S; Maneeton, B; Maneeton, N; Srisurapanont, M; Woottiluk, P | 1 |
Inoue, T; Kanno, T; Shimura, A | 1 |
Carvalho, AF; Chang, CH; Hsu, CW; Hsu, TW; Liang, CS; Thompson, T; Tsai, TC; Tseng, PT; Tu, YK; Yang, FC; Yang, SN; Yu, CL | 1 |
Beaucage-Charron, J; Coveney, R; Rinfret, J; Williamson, D | 1 |
Chiba, A; Iwashita, H; Kawaguchi, M; Sano, M; Suzuki, C | 1 |
Jin, Y; Li, S; Zhang, H | 1 |
Bourgin, P; Chambe, J; Geoffroy, PA; Maruani, J; Palagini, L; Reynaud, E | 1 |
Aksakalli-Magden, ZB; Alper, F; Aydin, P; Civelek, MS; Halici, Z; Karabulut-Uzuncakmak, S; Mokhtare, B; Ozkaraca, M | 1 |
Balpınar, Ö; Hacımüftüoğlu, A; Nadaroğlu, H | 1 |
40 review(s) available for melatonin and ramelteon
Article | Year |
---|---|
Melatonin, sleep, and circadian rhythms: rationale for development of specific melatonin agonists.
Topics: Acetamides; Antioxidants; Humans; Hypothalamus; Indenes; Indoles; Melatonin; Receptors, Melatonin; Sleep Disorders, Circadian Rhythm | 2004 |
Melatonin and sleep in aging population.
Topics: Aged; Aging; Alzheimer Disease; Body Temperature Regulation; Female; Humans; Indenes; Indoles; Male; Melatonin; Pineal Gland; Receptors, Melatonin; Sleep; Sleep Wake Disorders; Suprachiasmatic Nucleus | 2005 |
Ramelteon: a novel treatment for the treatment of insomnia.
Topics: Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Indenes; Melatonin; Practice Patterns, Physicians'; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 2006 |
Searching for new options for treating insomnia: are melatonin and ramelteon beneficial?
Topics: Administration, Intranasal; Adult; Aged; Circadian Rhythm; Female; Humans; Indenes; Injections, Intravenous; Male; Melatonin; Middle Aged; Randomized Controlled Trials as Topic; Sleep; Sleep Initiation and Maintenance Disorders | 2006 |
[Melatonin, melatonin receptor agonists and tryptophan as sleep aids].
Topics: Acetamides; Animals; Antioxidants; Humans; Hypnotics and Sedatives; Indenes; Melatonin; Receptors, Melatonin; Sleep Wake Disorders; Tryptophan | 2007 |
Pharmacotherapy for insomnia.
Topics: Antidepressive Agents; Azabicyclo Compounds; Central Nervous System Depressants; Eszopiclone; GABA Agonists; GABA-A Receptor Antagonists; Humans; Indenes; Melatonin; Phytotherapy; Piperazines; Pyridines; Sleep Initiation and Maintenance Disorders; Valerian; Zolpidem | 2008 |
[Drugs for insomnia and improving quality of life (QOL): research and development of ramelteon, an MT1/MT2-receptor agonist].
Topics: Animals; Humans; Indenes; Melatonin; Quality of Life; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders | 2008 |
Melatonergic drugs in clinical practice.
Topics: Acetamides; Animals; Antidepressive Agents; Biological Clocks; Humans; Hypnotics and Sedatives; Indenes; Melatonin; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders | 2008 |
The effect of melatonergic and non-melatonergic antidepressants on sleep: weighing the alternatives.
Topics: Acetamides; Affect; Antidepressive Agents; Brain; Depressive Disorder, Major; Humans; Indenes; Melatonin; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Sleep; Sleep Initiation and Maintenance Disorders | 2009 |
Melatonin and melatonergic drugs on sleep: possible mechanisms of action.
Topics: Acetamides; Aging; Animals; Antidepressive Agents; Circadian Rhythm; Depressive Disorder; Humans; Hypnotics and Sedatives; Indenes; Melatonin; Receptors, Melatonin; Signal Transduction; Sleep; Sleep Initiation and Maintenance Disorders; Suprachiasmatic Nucleus | 2009 |
Ramelteon: a review of its therapeutic potential in sleep disorders.
Topics: Animals; Humans; Indenes; Melatonin; Sleep; Sleep Initiation and Maintenance Disorders | 2009 |
Melatonin agonists and insomnia.
Topics: Acetamides; Animals; Benzofurans; Circadian Rhythm; Cyclopropanes; Humans; Hypnotics and Sedatives; Indenes; Melatonin; Sleep Initiation and Maintenance Disorders | 2010 |
Melatonin: pharmacological aspects and clinical trends.
Topics: Animals; Antidepressive Agents; Antioxidants; Depression; Free Radical Scavengers; Humans; Indenes; Jet Lag Syndrome; Melatonin; Receptors, Melatonin; Sleep; Sleep Disorders, Circadian Rhythm | 2010 |
Jet lag, circadian rhythm sleep disturbances, and depression: the role of melatonin and its analogs.
Topics: Acetamides; Benzofurans; Central Nervous System Depressants; Cyclopropanes; Depressive Disorder; Humans; Indenes; Jet Lag Syndrome; Melatonin; Sleep Disorders, Circadian Rhythm | 2010 |
Melatonin agonists in primary insomnia and depression-associated insomnia: are they superior to sedative-hypnotics?
Topics: Acetamides; Animals; Benzodiazepines; Benzofurans; Clinical Trials as Topic; Cyclopropanes; Depressive Disorder; Humans; Hypnotics and Sedatives; Indenes; Indoles; Melatonin; Sleep Initiation and Maintenance Disorders | 2011 |
Melatonin and its analogs in insomnia and depression.
Topics: Acetamides; Animals; Depression; Humans; Hypnotics and Sedatives; Indenes; Melatonin; Mice; Sleep Initiation and Maintenance Disorders | 2012 |
Emerging targets for the pharmacological treatment of depression: focus on melatonergic system.
Topics: Acetamides; Antidepressive Agents; Circadian Clocks; Depression; Humans; Indenes; Melatonin; Receptors, Melatonin | 2012 |
Melatonergic drugs for therapeutic use in insomnia and sleep disturbances of mood disorders.
Topics: Animals; Central Nervous System Depressants; Humans; Indenes; Melatonin; Mood Disorders; Sleep Initiation and Maintenance Disorders | 2012 |
Melatonin and synthetic melatonergic agonists: actions and metabolism in the central nervous system.
Topics: Acetamides; Animals; Antidepressive Agents; Central Nervous System; Humans; Indenes; Melatonin; Receptors, Melatonin; Sleep | 2012 |
Pharmacotherapies for sleep disturbances in Alzheimer's disease.
Topics: Alzheimer Disease; Humans; Indenes; Melatonin; Randomized Controlled Trials as Topic; Sleep; Sleep Wake Disorders; Trazodone | 2014 |
Melatonin and melatonin agonist for delirium in the elderly patients.
Topics: Aged; Delirium; Humans; Indenes; Melatonin; Randomized Controlled Trials as Topic | 2015 |
Therapeutic effects of melatonin receptor agonists on sleep and comorbid disorders.
Topics: Acetamides; Animals; Benzofurans; Clinical Trials as Topic; Cyclopropanes; Humans; Hypnotics and Sedatives; Indenes; Melatonin; Neurodegenerative Diseases; Receptors, Melatonin; Sleep Wake Disorders | 2014 |
Melatonin and Melatonin Agonists as Adjunctive Treatments in Bipolar Disorders.
Topics: Antipsychotic Agents; Benzofurans; Bipolar Disorder; Circadian Rhythm; Cyclopropanes; Humans; Inappropriate Prescribing; Indenes; Melatonin; Off-Label Use; Patient Safety; Practice Patterns, Physicians'; Receptors, Melatonin; Risk Assessment; Risk Factors; Sleep; Treatment Outcome | 2015 |
Emerging Role of Melatonin and Melatonin Receptor Agonists in Sleep and Delirium in Intensive Care Unit Patients.
Topics: Central Nervous System Depressants; Critical Care; Critical Illness; Delirium; Humans; Indenes; Intensive Care Units; Melatonin; Receptors, Melatonin; Sleep; Sleep Deprivation | 2016 |
Exogenous Melatonin for Delirium Prevention: a Meta-analysis of Randomized Controlled Trials.
Topics: Aged; Aged, 80 and over; Delirium; Female; Humans; Indenes; Male; Melatonin; Outcome Assessment, Health Care; Publication Bias; Randomized Controlled Trials as Topic; Risk Factors | 2016 |
The role of melatonin and melatonin agonists in counteracting antipsychotic-induced metabolic side effects: a systematic review.
Topics: Antioxidants; Antipsychotic Agents; Humans; Indenes; Melatonin; Metabolic Syndrome; Randomized Controlled Trials as Topic; Weight Gain | 2016 |
Melatonin based therapies for delirium and dementia.
Topics: Aged; Animals; Antipsychotic Agents; Benzodiazepines; Chronobiology Phenomena; Clinical Trials as Topic; Delirium; Dementia; Drug Therapy, Combination; Galantamine; Humans; Indenes; Melatonin; Memantine; Neuroprotection; Practice Guidelines as Topic | 2016 |
Melatonin Receptor Agonists for Delirium Prevention.
Topics: Clinical Trials as Topic; Delirium; Female; Humans; Hypnotics and Sedatives; Indenes; Melatonin; Prospective Studies; Receptors, Melatonin; Treatment Outcome; Tryptophan | 2017 |
Pharmacotherapies for sleep disturbances in dementia.
Topics: Alzheimer Disease; Humans; Indenes; Melatonin; Randomized Controlled Trials as Topic; Sleep; Sleep Wake Disorders; Time Factors; Trazodone | 2016 |
Prophylactic use of exogenous melatonin and melatonin receptor agonists to improve sleep and delirium in the intensive care units: a systematic review and meta-analysis of randomized controlled trials.
Topics: Adult; Benzofurans; Case-Control Studies; Correlation of Data; Cross-Sectional Studies; Cyclopropanes; Delirium; Hospital Mortality; Humans; Indenes; Intensive Care Units; Length of Stay; Melatonin; Randomized Controlled Trials as Topic; Receptors, Melatonin; Respiration, Artificial; Risk Factors; Sleep; Sleep Wake Disorders; Treatment Outcome; Wakefulness | 2019 |
The effect of melatonin on delirium in hospitalised patients: A systematic review and meta-analyses with trial sequential analysis.
Topics: Delirium; Dizziness; Headache; Hospital Mortality; Humans; Hypnotics and Sedatives; Incidence; Indenes; Intensive Care Units; Length of Stay; Melatonin; Nausea; Paresthesia; Randomized Controlled Trials as Topic; Respiration, Artificial; Restraint, Physical; Treatment Outcome | 2020 |
Melatonergic agents in the prevention of delirium: A network meta-analysis of randomized controlled trials.
Topics: Aged; Delirium; Humans; Indenes; Melatonin; Network Meta-Analysis; Randomized Controlled Trials as Topic; Risk Factors | 2020 |
The role of melatonin and melatonin receptor agonist in the prevention of sleep disturbances and delirium in intensive care unit - a clinical review.
Topics: Chronobiology Disorders; Delirium; Humans; Indenes; Intensive Care Units; Melatonin; Receptors, Melatonin; Sleep; Sleep Deprivation | 2020 |
Melatonin and its analogues for the prevention of postoperative delirium: A systematic review and meta-analysis.
Topics: Emergence Delirium; Humans; Indenes; Melatonin | 2020 |
Pharmacotherapies for sleep disturbances in dementia.
Topics: Alzheimer Disease; Azepines; Caregiver Burden; Cognition; Humans; Indenes; Melatonin; Pyridines; Pyrimidines; Randomized Controlled Trials as Topic; Sleep; Sleep Wake Disorders; Time Factors; Trazodone; Triazoles | 2020 |
Antidepressant actions of melatonin and melatonin receptor agonist: Focus on pathophysiology and treatment.
Topics: Animals; Antidepressive Agents; Antioxidants; Benzofurans; Chronobiology Disorders; Cyclopropanes; Depression; Humans; Hypothalamo-Hypophyseal System; Indenes; Melatonin; Pituitary-Adrenal System; Receptors, Melatonin; Sleep Wake Disorders | 2022 |
Melatonin Receptor Agonists for the Prevention of Delirium: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Topics: Aged; Delirium; Humans; Indenes; Melatonin; Randomized Controlled Trials as Topic; Receptors, Melatonin | 2022 |
Ramelteon for delirium prevention in hospitalized patients: An updated meta-analysis and trial sequential analysis of randomized controlled trials.
Topics: Delirium; Humans; Melatonin; Middle Aged; Randomized Controlled Trials as Topic; Reproducibility of Results | 2023 |
Melatonin and Ramelteon for the treatment of delirium: A systematic review and meta-analysis.
Topics: Aged; Antipsychotic Agents; Delirium; Humans; Indenes; Melatonin | 2023 |
Efficacy of melatonin and ramelteon for the acute and long-term management of insomnia disorder in adults: A systematic review and meta-analysis.
Topics: Adult; Humans; Indenes; Melatonin; Sleep; Sleep Initiation and Maintenance Disorders | 2023 |
8 trial(s) available for melatonin and ramelteon
Article | Year |
---|---|
An efficacy, safety, and dose-response study of Ramelteon in patients with chronic primary insomnia.
Topics: Adolescent; Adult; Chronic Disease; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Indenes; Male; Melatonin; Middle Aged; Polysomnography; Sleep Initiation and Maintenance Disorders; Surveys and Questionnaires; Treatment Outcome | 2006 |
Circadian phase-shifting effects of repeated ramelteon administration in healthy adults.
Topics: Administration, Oral; Adolescent; Adult; Circadian Rhythm; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Indenes; Male; Melatonin; Polysomnography; Sleep; Young Adult | 2008 |
Safety and subjective sleep effects of ramelteon administration in adults and older adults with chronic primary insomnia: a 1-year, open-label study.
Topics: Adolescent; Adult; Aged; Chronic Disease; Dose-Response Relationship, Drug; Female; Humans; Indenes; Male; Melatonin; Middle Aged; Severity of Illness Index; Single-Blind Method; Sleep Initiation and Maintenance Disorders; Surveys and Questionnaires; Testosterone; Thyroxine; Young Adult | 2009 |
Effects of ramelteon on insomnia symptoms induced by rapid, eastward travel.
Topics: Actigraphy; Adult; Case-Control Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Indenes; Jet Lag Syndrome; Male; Melatonin; Neuropsychological Tests; Pain Measurement; Young Adult | 2010 |
Intrinsic circadian period of sighted patients with circadian rhythm sleep disorder, free-running type.
Topics: Adolescent; Adult; Case-Control Studies; Chronotherapy; Circadian Rhythm; Female; Humans; Indenes; Male; Melatonin; Middle Aged; Photoperiod; Phototherapy; Polysomnography; Receptors, Melatonin; Sleep; Sleep Disorders, Circadian Rhythm; Wakefulness | 2013 |
[Treatment with ramelteon for sleep disturbance in severely disabled children and young adults].
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Indenes; Male; Melatonin; Sleep; Sleep Initiation and Maintenance Disorders; Sleep Stages; Treatment Outcome; Young Adult | 2013 |
Effect of add-on ramelteon therapy on sleep and circadian rhythm disruption in patients with schizophrenia: A randomized controlled trial.
Topics: Adult; Antipsychotic Agents; Circadian Rhythm; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Indenes; Male; Melatonin; Middle Aged; Schizophrenia; Single-Blind Method; Sleep; Treatment Outcome; Young Adult | 2020 |
Effect of enterally administered sleep-promoting medication on the intravenous sedative dose and its safety and cost profile in mechanically ventilated patients: A retrospective cohort study.
Topics: Administration, Intravenous; Aged; Central Nervous System Depressants; Enteral Nutrition; Female; Humans; Hypnotics and Sedatives; Indenes; Intensive Care Units; Length of Stay; Male; Melatonin; Middle Aged; Propofol; Respiration, Artificial; Retrospective Studies; Sleep | 2021 |
38 other study(ies) available for melatonin and ramelteon
Article | Year |
---|---|
Synthesis of a novel series of tricyclic indan derivatives as melatonin receptor agonists.
Topics: Animals; Binding Sites; Cats; CHO Cells; Cricetinae; Cyclic AMP; Female; Humans; In Vitro Techniques; Indans; Male; Melatonin; Mesocricetus; Models, Molecular; Organ Specificity; Pituitary Gland; Radioligand Assay; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Sleep; Stereoisomerism; Structure-Activity Relationship; Wakefulness | 2002 |
Design and synthesis of 4-arylpiperidinyl amide and N-arylpiperdin-3-yl-cyclopropane carboxamide derivatives as novel melatonin receptor ligands.
Topics: Amides; Animals; Cyclopropanes; Drug Design; Humans; Ligands; Microsomes; Piperidines; Rats; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Structure-Activity Relationship | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential.
Topics: Animals; Binding Sites; Depressive Disorder; Humans; Ligands; Melatonin; Models, Molecular; Protein Multimerization; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep Initiation and Maintenance Disorders; Structure-Activity Relationship | 2014 |
Effects of ramelteon (TAK-375) on nocturnal sleep in freely moving monkeys.
Topics: Amides; Animals; Dose-Response Relationship, Drug; Electroencephalography; Female; Hypnotics and Sedatives; Indenes; Macaca fascicularis; Melatonin; Polysomnography; Pyridines; Reaction Time; Receptors, Melatonin; Sleep; Time Factors; Wakefulness; Zolpidem | 2004 |
The sleep-promoting action of ramelteon (TAK-375) in freely moving cats.
Topics: Animals; Arousal; Cats; Circadian Rhythm; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Indenes; Male; Melatonin; Polysomnography; Sleep; Sleep, REM; Suprachiasmatic Nucleus; Wakefulness | 2004 |
Ramelteon (Rozerem) for insomnia.
Topics: Humans; Indenes; Melatonin; Receptor, Melatonin, MT1; Sleep Initiation and Maintenance Disorders | 2005 |
Design and synthesis of new N1 and C3-substituted 4-fluoroindolic melatoninergics.
Topics: Animals; Chromatography; Drug Design; Humans; Indenes; Indoles; Iodine Radioisotopes; Mass Spectrometry; Melanophores; Melatonin; Mice; Molecular Structure; NIH 3T3 Cells; Protein Binding; Radioligand Assay; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Transition Temperature; Tryptamines; Xenopus laevis | 2007 |
Acute sleep-promoting action of the melatonin agonist, ramelteon, in the rat.
Topics: Animals; Electroencephalography; Humans; Indenes; Melatonin; Mice; Molecular Structure; NIH 3T3 Cells; Rats; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep | 2008 |
Melatonin and its agonists: an update.
Topics: Acetamides; Benzofurans; Cyclopropanes; Drug Administration Schedule; Humans; Indenes; Melatonin; Receptors, Melatonin | 2008 |
Let there be sleep--on time.
Topics: Circadian Rhythm; Humans; Indenes; Melatonin; Randomized Controlled Trials as Topic; Receptors, Melatonin; Sleep; Sleep Initiation and Maintenance Disorders | 2009 |
Influence of the novel antidepressant and melatonin agonist/serotonin2C receptor antagonist, agomelatine, on the rat sleep-wake cycle architecture.
Topics: Acetamides; Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Depressants; Circadian Rhythm; Hypnotics and Sedatives; Indenes; Indoles; Melatonin; Pyridines; Rats; Rats, Wistar; Serotonin Antagonists; Sleep; Wakefulness | 2009 |
Molecular cloning and pharmacological characterization of monkey MT1 and MT2 melatonin receptors showing high affinity for the agonist ramelteon.
Topics: Amino Acid Sequence; Animals; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; DNA; Female; Indenes; Macaca fascicularis; Male; Melatonin; Molecular Sequence Data; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sleep | 2009 |
MT1 melatonin receptors mediate somatic, behavioral, and reproductive neuroendocrine responses to photoperiod and melatonin in Siberian hamsters (Phodopus sungorus).
Topics: 5-Methoxytryptamine; Animals; Circadian Rhythm; Cricetinae; Indenes; Male; Melatonin; Motor Activity; Phodopus; Photoperiod; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Seasons; Signal Transduction | 2010 |
Circadian periods of sensitivity for ramelteon on the onset of running-wheel activity and the peak of suprachiasmatic nucleus neuronal firing rhythms in C3H/HeN mice.
Topics: Animals; Circadian Rhythm; Indenes; Male; Melatonin; Mice; Mice, Inbred C3H; Motor Activity; Receptors, Melatonin; Running; Sleep Initiation and Maintenance Disorders; Suprachiasmatic Nucleus | 2011 |
Gender-related invasion differences associated with mRNA expression levels of melatonin membrane receptors in colorectal cancer.
Topics: Aged; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Immunoblotting; Indenes; Male; Melatonin; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Factors | 2012 |
[Delirium, insomnia in hospitalization and ramelteon].
Topics: Delirium; Hospitalization; Humans; Indenes; Melatonin; Sleep Initiation and Maintenance Disorders | 2012 |
Circadian system functionality, hippocampal oxidative stress, and spatial memory in the APPswe/PS1dE9 transgenic model of Alzheimer disease: effects of melatonin or ramelteon.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Body Temperature; Circadian Rhythm; Disease Models, Animal; Hippocampus; Indenes; Male; Melatonin; Memory; Mice; Mice, Transgenic; Motor Activity; Mutant Proteins; Oxidative Stress; Presenilin-1; Receptors, Melatonin | 2012 |
Marked improvement in delirium with ramelteon: five case reports.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Circadian Rhythm; Delirium; Female; Humans; Indenes; Male; Melatonin; Treatment Outcome | 2012 |
Melatonin receptor activation suppresses adrenocorticotropin production via BMP-4 action by pituitary AtT20 cells.
Topics: Adrenocorticotropic Hormone; Animals; Bone Morphogenetic Protein 4; Cell Line; Corticotrophs; Culture Media, Serum-Free; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression; Humans; Indenes; MAP Kinase Signaling System; Melatonin; Mice; Pituitary Gland; Pro-Opiomelanocortin; Rats; Rats, Wistar; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Smad Proteins | 2013 |
Melatonin receptors mediate improvements of survival in a model of polymicrobial sepsis.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Indenes; Interleukin-10; Interleukin-6; Male; Melatonin; Mice; Mice, Inbred C3H; Mice, Knockout; Rats; Rats, Sprague-Dawley; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, Melatonin; Sepsis; Tryptamines; Tumor Necrosis Factor-alpha | 2014 |
Effects of Kaixin Powder on melatonin receptor expression and (125)I-Mel binding affinity in a rat model of depression.
Topics: Animals; Brain; Depression; Disease Models, Animal; Drinking Behavior; Drugs, Chinese Herbal; Gene Expression Regulation; Indenes; Iodine Radioisotopes; Male; Melatonin; Rats, Wistar; Receptors, Melatonin; Weight Gain | 2015 |
[A nationwide survey on the uses of melatonin and ramelteon in Japanese children].
Topics: Adolescent; Adult; Child; Child, Preschool; Circadian Rhythm; Data Collection; Female; Humans; Indenes; Infant; Japan; Male; Melatonin; Sleep; Sleep Initiation and Maintenance Disorders; Young Adult | 2015 |
Melatonin or ramelteon therapy differentially affects hepatic gene expression profiles after haemorrhagic shock in rat--A microarray analysis.
Topics: Animals; Antioxidants; Biomarkers, Tumor; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Indenes; Liver; Male; Melatonin; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Shock, Hemorrhagic; Tumor Cells, Cultured | 2015 |
GIRK Channels Mediate the Nonphotic Effects of Exogenous Melatonin.
Topics: Animals; Bee Venoms; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Indenes; Male; Melatonin; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Culture Techniques; Potassium Channel Blockers; Suprachiasmatic Nucleus | 2015 |
Melatonin Receptor Agonists as the "Perioceutics" Agents for Periodontal Disease through Modulation of Porphyromonas gingivalis Virulence and Inflammatory Response.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Biofilms; Cells, Cultured; Fibroblasts; Gene Expression Regulation, Bacterial; Hemolysis; Humans; Indenes; Interleukin-6; Interleukin-8; Melatonin; Periodontal Diseases; Porphyromonas gingivalis; Receptors, Melatonin; Sheep | 2016 |
Role of Ramelteon in Reduction of As-Needed Antipsychotics in Elderly Patients with Delirium in a General Hospital Setting.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Female; Hospitals, General; Humans; Incidence; Indenes; Male; Melatonin; Retrospective Studies | 2017 |
XFEL structures of the human MT
Topics: Crystallization; Diabetes Mellitus, Type 2; Electrons; Humans; Indenes; Lasers; Ligands; Melatonin; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Structure-Activity Relationship; Substrate Specificity | 2019 |
Structural basis of ligand recognition at the human MT
Topics: Acetamides; Amino Acid Sequence; Antidepressive Agents; Crystallization; Electrons; Humans; Indenes; Lasers; Ligands; Melatonin; Models, Molecular; Molecular Docking Simulation; Mutation; Receptor, Melatonin, MT1; Receptor, Serotonin, 5-HT2C; Structure-Activity Relationship; Substrate Specificity | 2019 |
Do peripheral melatonin agonists improve bone fracture healing? The effects of agomelatine and ramelteon on experimental bone fracture.
Topics: Acetamides; Animals; Femoral Fractures; Fracture Healing; Fractures, Bone; Indenes; Male; Melatonin; Osteogenesis; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; X-Rays | 2020 |
Evaluation of Delirium in Critically Ill Patients Prescribed Melatonin or Ramelteon.
Topics: Critical Illness; Delirium; Humans; Hypnotics and Sedatives; Indenes; Intensive Care Units; Melatonin; Respiration, Artificial; Retrospective Studies | 2021 |
Therapeutic potential of melatonin and melatonergic drugs on K18-hACE2 mice infected with SARS-CoV-2.
Topics: Acetamides; Animals; COVID-19; COVID-19 Drug Treatment; Indenes; Lung; Melatonin; Mice; Mice, Inbred C57BL; Mice, Transgenic; SARS-CoV-2; Viral Load | 2022 |
Structural basis of the ligand binding and signaling mechanism of melatonin receptors.
Topics: Amino Acid Motifs; Cryoelectron Microscopy; Humans; Indenes; Ligands; Melatonin; Protein Binding; Protein Conformation; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2 | 2022 |
Ultra-low-dose early night ramelteon administration for the treatment of delayed sleep-wake phase disorder: case reports with a pharmacological review.
Topics: Circadian Rhythm; Humans; Indenes; Melatonin; Sleep; Sleep Disorders, Circadian Rhythm; Sleep Wake Disorders | 2022 |
Effects of melatonin on phosphorylation of memory-related proteins in the hippocampus and the perirhinal cortex in male mice.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Extracellular Signal-Regulated MAP Kinases; Hippocampus; Male; Melatonin; Mice; Perirhinal Cortex; Phosphorylation | 2023 |
Remote ischemic preconditioning-induced late cardioprotection: possible role of melatonin-mitoKATP-H2S signaling pathway.
Topics: Animals; Ischemia; Ischemic Preconditioning; Ischemic Preconditioning, Myocardial; KATP Channels; Melatonin; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Signal Transduction; Tumor Necrosis Factor-alpha | 2023 |
The melatonin agonist ramelteon attenuates bleomycin-induced lung fibrosis by suppressing the NLRP3/TGF-Β1/HMGB1 signaling pathway.
Topics: Animals; Bleomycin; HMGB1 Protein; Lung; Melatonin; NLR Family, Pyrin Domain-Containing 3 Protein; Pulmonary Fibrosis; Rats; Signal Transduction; Transforming Growth Factor beta1 | 2023 |
Green synthesis, characterization of melatonin-like drug bioconjugated CoS quantum dots and its antiproliferative effect on different cancer cells.
Topics: Cell Line, Tumor; Humans; Male; Melatonin; Neuroblastoma; Prostatic Neoplasms; Quantum Dots | 2023 |