melatonin and memantine

melatonin has been researched along with memantine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's14 (82.35)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cano-Abad, MF; de los Ríos, C; González-Lafuente, L; Lajarín-Cuesta, R; Martínez-Sanz, FJ; Moreno-Ortega, AJ; Punzón, E1
Araujo de Brito, M; Arranz-Tagarro, JA; Arribas, RL; de Los Ríos, C; Gandía, L; González-Lafuente, L; Lajarín-Cuesta, R; Nanclares, C1
Arribas, RL; de Los Ríos, C; Gandía, L; García-Frutos, EM; Lajarín-Cuesta, R; Nanclares, C1
Kilic, E; Kilic, U; Reiter, RJ; Yilmaz, B; Yüksel, A1
Hendren, RL1
Ferriero, DM; Juul, SE1
Farmer, M; Frydman-Marom, A; Fund, N; Harari, G; Laudon, M; Nir, T; Wade, AG; Zisapel, N1
Beker, MC; Caglayan, AB; Caglayan, B; Gundogdu, RZ; Kelestemur, T; Kilic, E; Kilic, U; Yalcin, E; Yulug, B1
Daulatzai, MA1
Alagiakrishnan, K1
Bardak, H; Bardak, Y; Uğuz, AC1
Beniashvili, A; Jürgenson, M; Morozova, M; Noortoots, A; Zapolski, M; Zharkovskaja, T; Zharkovsky, A1
Abbasinazari, M; Badri, T; Ghassab-Sahebkar, A; Keshvari, N; Qobadighadikolaei, R; Sarraf, N1
Majidazar, R; Naseri, A; Rezazadeh-Gavgani, E; Sadigh-Eteghad, S1
Andrade, C1

Reviews

6 review(s) available for melatonin and memantine

ArticleYear
Autism: biomedical complementary treatment approaches.
    Child and adolescent psychiatric clinics of North America, 2013, Volume: 22, Issue:3

    Topics: Acetylcysteine; Central Nervous System Depressants; Chelation Therapy; Child; Child Development Disorders, Pervasive; Complementary Therapies; Excitatory Amino Acid Antagonists; Fatty Acids, Omega-3; Humans; Immunoglobulins, Intravenous; Melatonin; Memantine; Micronutrients; Treatment Outcome; Vitamin B 12

2013
Pharmacologic neuroprotective strategies in neonatal brain injury.
    Clinics in perinatology, 2014, Volume: 41, Issue:1

    Topics: Acetylcysteine; Allopurinol; Antioxidants; Ascorbic Acid; Biopterins; Erythropoietin; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Fructose; Humans; Hypoxia-Ischemia, Brain; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Melatonin; Memantine; Neuroprotective Agents; Nitric Oxide Synthase Type III; Resveratrol; Stilbenes; Topiramate; Vitamin E; Xenon

2014
Pharmacotherpy and Alzheimer's Disease: The M-Drugs (Melatonin, Minocycline, Modafinil, and Memantine) Approach.
    Current pharmaceutical design, 2016, Volume: 22, Issue:16

    Topics: Alzheimer Disease; Animals; Benzhydryl Compounds; Cognitive Dysfunction; Humans; Melatonin; Memantine; Minocycline; Modafinil

2016
Melatonin based therapies for delirium and dementia.
    Discovery medicine, 2016, Volume: 21, Issue:117

    Topics: Aged; Animals; Antipsychotic Agents; Benzodiazepines; Chronobiology Phenomena; Clinical Trials as Topic; Delirium; Dementia; Drug Therapy, Combination; Galantamine; Humans; Indenes; Melatonin; Memantine; Neuroprotection; Practice Guidelines as Topic

2016
Pharmacotherapy of Alzheimer's disease: an overview of systematic reviews.
    European journal of clinical pharmacology, 2022, Volume: 78, Issue:10

    Topics: Alzheimer Disease; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Cholinesterase Inhibitors; Donepezil; Galantamine; Glycogen Synthase Kinase 3; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Indans; Lithium; Melatonin; Memantine; Neurodegenerative Diseases; Rivastigmine; Systematic Reviews as Topic

2022
Reconsideration of the Benefits of Pharmacological Interventions for the Attenuation of the Cognitive Adverse Effects of Electroconvulsive Therapy.
    The Journal of clinical psychiatry, 2022, 10-03, Volume: 83, Issue:5

    Topics: Calcium Channel Blockers; Cholinesterase Inhibitors; Cognition; Electroconvulsive Therapy; Humans; Hydrocortisone; Ketamine; Melatonin; Memantine; Narcotic Antagonists; Nortriptyline; Pemoline; Piracetam; Treatment Outcome; Triiodothyronine; Tryptophan

2022

Trials

2 trial(s) available for melatonin and memantine

ArticleYear
Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer's disease: a 6-month, randomized, placebo-controlled, multicenter trial.
    Clinical interventions in aging, 2014, Volume: 9

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Delayed-Action Preparations; Dopamine Agents; Drug Therapy, Combination; Female; Humans; Male; Melatonin; Memantine; Middle Aged; Placebos; Severity of Illness Index; Sleep; Sleep Initiation and Maintenance Disorders; Treatment Outcome

2014
Comparison of the efficacy and safety of melatonin and memantine in the alleviation of cognitive impairments induced by electroconvulsive therapy: A randomized clinical trial.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 74

    Topics: Adult; Aged; Cognition; Cognitive Dysfunction; Depressive Disorder, Major; Electroconvulsive Therapy; Female; Humans; Male; Melatonin; Memantine; Middle Aged; Treatment Outcome

2020

Other Studies

9 other study(ies) available for melatonin and memantine

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Neuroprotective profile of pyridothiazepines with blocking activity of the mitochondrial Na(+)/Ca(2+) exchanger.
    European journal of medicinal chemistry, 2016, Feb-15, Volume: 109

    Topics: Animals; Calcium; Cattle; Cell Line; Cell Line, Tumor; HeLa Cells; Hippocampus; Humans; Mitochondria; Neuroprotective Agents; Pyridines; Rats; Sodium-Calcium Exchanger; Solubility; Thiazepines

2016
Gramine Derivatives Targeting Ca(2+) Channels and Ser/Thr Phosphatases: A New Dual Strategy for the Treatment of Neurodegenerative Diseases.
    Journal of medicinal chemistry, 2016, 07-14, Volume: 59, Issue:13

    Topics: Alkaloids; Animals; Calcium Channels; Cattle; Cell Survival; Dose-Response Relationship, Drug; Hippocampus; Humans; Indole Alkaloids; Molecular Structure; Neurodegenerative Diseases; Phosphoprotein Phosphatases; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tumor Cells, Cultured

2016
Design and synthesis of multipotent 3-aminomethylindoles and 7-azaindoles with enhanced protein phosphatase 2A-activating profile and neuroprotection.
    European journal of medicinal chemistry, 2018, Sep-05, Volume: 157

    Topics: Aza Compounds; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Humans; Indoles; Molecular Structure; Neuroprotective Agents; Protein Phosphatase 2; Structure-Activity Relationship; Tumor Cells, Cultured

2018
Effects of memantine and melatonin on signal transduction pathways vascular leakage and brain injury after focal cerebral ischemia in mice.
    Neuroscience, 2013, May-01, Volume: 237

    Topics: Analysis of Variance; Animals; Cerebral Cortex; Cerebral Infarction; Corpus Striatum; Disease Models, Animal; DNA Fragmentation; Immunoglobulin G; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Male; MAP Kinase Signaling System; Melatonin; Memantine; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Phosphorylation; Signal Transduction

2013
Targeting different pathophysiological events after traumatic brain injury in mice: Role of melatonin and memantine.
    Neuroscience letters, 2016, Jan-26, Volume: 612

    Topics: Animals; Brain; Brain Infarction; Brain Injuries; DNA Fragmentation; Free Radical Scavengers; Male; Melatonin; Memantine; Mice, Inbred BALB C; Neuroprotective Agents

2016
Protective effects of melatonin and memantine in human retinal pigment epithelium (ARPE-19) cells against 2-ethylpyridine-induced oxidative stress: implications for age-related macular degeneration.
    Cutaneous and ocular toxicology, 2018, Volume: 37, Issue:2

    Topics: Apoptosis; Caspase 3; Caspase 9; Cell Line; Epithelial Cells; Glutathione; Glutathione Peroxidase; Humans; Macular Degeneration; Melatonin; Memantine; Membrane Potential, Mitochondrial; Oxidative Stress; Protective Agents; Pyridines; Reactive Oxygen Species; Retinal Pigment Epithelium; Vascular Endothelial Growth Factor A

2018
Effects of the drug combination memantine and melatonin on impaired memory and brain neuronal deficits in an amyloid-predominant mouse model of Alzheimer's disease.
    The Journal of pharmacy and pharmacology, 2019, Volume: 71, Issue:11

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cholinesterase Inhibitors; Disease Models, Animal; Drug Combinations; Female; Male; Maze Learning; Melatonin; Memantine; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Peptide Fragments

2019