melatonin has been researched along with levodopa in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (22.22) | 18.7374 |
| 1990's | 10 (22.22) | 18.2507 |
| 2000's | 14 (31.11) | 29.6817 |
| 2010's | 10 (22.22) | 24.3611 |
| 2020's | 1 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Audibert, B; Perrottet, E | 1 |
| Allen, JP; Bell, R; Jordan, RM; McDonald, SD; Stevens, EA; Vaughan, GM | 1 |
| Arendt, J | 1 |
| Moore, DC; Paunier, L; Sizonenko, PC | 1 |
| Sandyk, R | 1 |
| Anninos, PA; Derpapas, K; Sandyk, R; Tsagas, N | 1 |
| Deng, MH; Lopez G-Coviella, I; Lynch, HJ; Wurtman, RJ | 1 |
| Auff, E; Doppelbauer, A; Fertl, E; Waldhauser, F | 2 |
| Abreu, P; Alonso, R; Calzadilla, CH; Hernandez, G; Santana, C | 1 |
| Mitsuma, T; Nogimori, T | 1 |
| Hadjiconstantinou, M; Neff, NH | 1 |
| Linkowski, P; Mendlewicz, J | 1 |
| Burg, AC; Horowitz, ZD; Weinberg, U; Weitzman, ED | 1 |
| Anisimov, VN | 1 |
| Krieger, M; Nguyen-Legros, J; Simon, A | 1 |
| Alexiuk, NA; Vriend, JP | 1 |
| Alexiuk, NA; Uddin, M; Vriend, J | 1 |
| Joseph, JA; Miller, JW; Selhub, J | 1 |
| Bieglmayer, C; Birnbacher, R; Blau, N; Frisch, H; Scheibenreiter, S; Waldhauser, F | 1 |
| Doroshenko, EM; Etingof, RN; Lavrikova, EV; Pozdeyev, NV | 1 |
| Abreu, P; Gonzalez, MC; Sanchez, JJ | 1 |
| Garcia-Borreguero, D; Granizo, JJ; Larrosa, O; Serrano, C | 1 |
| Birman, S; Coulom, H | 1 |
| Daya, S; Maharaj, H; Mokokong, R; Scheepers, M; Sukhdev Maharaj, D | 1 |
| Willis, GL | 1 |
| Desole, MS; Esposito, G; Marchetti, B; Miele, E; Migheli, R; Rocchitta, G; Serra, PA | 1 |
| Abreu-González, P; Afonso-Oramas, D; Barroso-Chinea, P; Cruz-Muros, I; González, MC; González-Hernández, T | 1 |
| Alexiuk, NA; Vriend, J | 1 |
| Fertl, E | 1 |
| Chaturvedi, CM; Kumar, P; Mohan, J; Pati, AK; Sastry, KV; Tyagi, JS | 1 |
| Chaturvedi, CM; Kumar, P | 1 |
| Borah, A; Mohanakumar, KP | 1 |
| Arnulf, I; Boniol, C; Clot, F; Decaix, C; Leu-Semenescu, S; Levy, R; Moussa, F; Roze, E; Touitou, Y; Vidailhet, M | 1 |
| Chakraborty, J; Dhanasekaran, M; Manivasagam, T; Mohanakumar, KP; Naskar, A; Singh, R; Thomas, B | 1 |
| Farag, NE; Hammad, LN; Zaitone, SA | 1 |
| Bolitho, SJ; Grunstein, RR; Hodges, JR; Lewis, SJ; Naismith, SL; Rajaratnam, SM; Rogers, N; Terpening, Z | 1 |
| Dutta, D; Mohanakumar, KP; Naskar, A; Prabhakar, V; Singh, R | 1 |
| Adrien, J; Belaid, H; François, C; Hirsch, EC; Karachi, C | 1 |
| Coleman-Jackson, R; Hershey, LA | 1 |
| Kataoka, H; Kurumatani, N; Obayashi, K; Saeki, K; Sugie, K | 1 |
4 review(s) available for melatonin and levodopa
| Article | Year |
|---|---|
Catecholamine systems of retina: a model for studying synaptic mechanisms.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Antipsychotic Agents; Darkness; Dopamine; Electrophysiology; Enzyme Activation; Epinephrine; Evoked Potentials, Visual; gamma-Aminobutyric Acid; Humans; Levodopa; Light; Melatonin; Narcotics; Neurons; Norepinephrine; Parkinson Disease; Receptors, Adrenergic; Retina; Schizophrenia; Serotonin | 1984 |
[Neuroendocrinology of depressive disorders].
Topics: Adrenocorticotropic Hormone; Depressive Disorder; Dexamethasone; Dextroamphetamine; Growth Hormone; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Levodopa; Melatonin; Periodicity; Prolactin; Thyrotropin; Thyrotropin-Releasing Hormone | 1982 |
The role of ML-23 and other melatonin analogues in the treatment and management of Parkinson's disease.
Topics: 5-Methoxytryptamine; Animals; Antiparkinson Agents; Disease Models, Animal; Humans; Levodopa; Melatonin; Parkinson Disease | 2005 |
Pharmacological Management of Dementia with Lewy Bodies.
Topics: Age Factors; Aged; Anticonvulsants; Antiparkinson Agents; Cholinesterase Inhibitors; Clinical Trials, Phase II as Topic; Clonazepam; Humans; Levodopa; Lewy Body Disease; Melatonin; Randomized Controlled Trials as Topic; Zonisamide | 2019 |
3 trial(s) available for melatonin and levodopa
| Article | Year |
|---|---|
Circadian secretion pattern of melatonin in Parkinson's disease.
Topics: Adult; Aged; Biomarkers; Circadian Rhythm; Female; Humans; Levodopa; Male; Melatonin; Middle Aged; Parkinson Disease | 1991 |
Lack of an effect of melatonin on the basal and L-dopa stimulated growth hormone secretion in men.
Topics: Adult; Growth Hormone; Humans; Kinetics; Levodopa; Male; Melatonin | 1981 |
Circadian effects of dopaminergic treatment in restless legs syndrome.
Topics: Adult; Circadian Rhythm; Dopamine Agents; Female; Humans; Levodopa; Lighting; Male; Melatonin; Middle Aged; Polysomnography; Restless Legs Syndrome; Saliva; Time Factors | 2004 |
38 other study(ies) available for melatonin and levodopa
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
[Hypothalamic hormones and the central nervous system].
Topics: Catecholamines; Central Nervous System; Corticotropin-Releasing Hormone; Cyclic AMP; Gonadotropin-Releasing Hormone; Growth Hormone-Releasing Hormone; Humans; Hypothalamus; Levodopa; Lithium; Melatonin; MSH Release-Inhibiting Hormone; Pituitary Hormone Release Inhibiting Hormones; Pituitary Hormone-Releasing Hormones; Prolactin Release-Inhibiting Factors; Psychotropic Drugs; Serotonin; Somatostatin; Thyrotropin-Releasing Hormone | 1975 |
Melatonin, pituitary function and stress in humans.
Topics: Adrenocorticotropic Hormone; Adult; Circadian Rhythm; Endocrine System Diseases; Female; Follicle Stimulating Hormone; Growth Hormone; Humans; Hydrocortisone; Levodopa; Luteinizing Hormone; Male; Melatonin; Physical Exertion; Pituitary Gland; Stress, Physiological; Thyrotropin | 1979 |
Melatonin assays in body fluids.
Topics: Acetyltransferases; Animals; Body Fluids; Circadian Rhythm; Female; Humans; Levodopa; Light; Male; Melatonin; Menstruation; Radioimmunoassay; Rats; Seasons | 1978 |
Effect of adrenergic stimulation and blockade on melatonin secretion in the human.
Topics: Adult; Circadian Rhythm; Humans; Levodopa; Male; Melatonin; Metaproterenol; Pineal Gland; Propranolol; Seasons | 1979 |
Accelerated growth of malignant melanoma by levodopa in Parkinson's disease and role of the pineal gland.
Topics: Combined Modality Therapy; Corpus Striatum; Dyskinesia, Drug-Induced; Electric Stimulation; Equipment Design; Humans; Levodopa; Magnetics; Male; Melatonin; Middle Aged; Parkinson Disease; Pineal Gland | 1992 |
Magnetic fields in the treatment of Parkinson's disease.
Topics: Combined Modality Therapy; Corpus Striatum; Dyskinesia, Drug-Induced; Electric Stimulation; Equipment Design; Humans; Levodopa; Magnetics; Male; Melatonin; Middle Aged; Parkinson Disease; Pineal Gland | 1992 |
Melatonin and its precursors in Y79 human retinoblastoma cells: effect of sodium butyrate.
Topics: 5-Hydroxytryptophan; Analysis of Variance; Butyrates; Butyric Acid; Cell Line; Colforsin; Dopamine; Eye Neoplasms; Humans; Kinetics; Levodopa; Melatonin; Retinoblastoma; Serotonin; Spiperone | 1991 |
Day-night rhythm of rat pineal tyrosine hydroxylase activity as determined by HPLC with amperometric detection.
Topics: Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Kinetics; Levodopa; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Tyrosine 3-Monooxygenase | 1987 |
Effects of various drugs on thyrotropin secretion in rats.
Topics: 5-Hydroxytryptophan; Animals; Dose-Response Relationship, Drug; Endorphins; Fenclonine; Haloperidol; Hypothalamus; Levodopa; Male; Melatonin; Phenytoin; Protein Precursors; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone; Time Factors | 1985 |
Study on serotoninergic mechanisms of compensatory ovarian hypertrophy in rats.
Topics: Animals; Brain; Castration; Diethylstilbestrol; Female; Hypertrophy; Indoles; Levodopa; Melatonin; Morpholines; Ovary; Pineal Gland; Pyridazines; Rats; Serotonin; Tryptophan | 1980 |
Immunohistochemical localization of L-dopa and aromatic L-amino acid-decarboxylase in the rat retina.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Dopamine; Fluorescent Antibody Technique; Immunoenzyme Techniques; Levodopa; Male; Melatonin; Rats; Rats, Wistar; Retina; Serotonin; Tyramine | 1994 |
Melatonin reduces dopamine content in the neurointermediate lobe of male Syrian hamsters.
Topics: Analysis of Variance; Animals; Cricetinae; Dopamine; Levodopa; Male; Melatonin; Mesocricetus; Norepinephrine; Organ Size; Pituitary Gland, Posterior; Testis; Time Factors | 1993 |
Circadian secretion pattern of melatonin in de novo parkinsonian patients: evidence for phase-shifting properties of l-dopa.
Topics: Aged; Circadian Rhythm; Female; Humans; Levodopa; Male; Melatonin; Middle Aged; Movement Disorders; Muscle Rigidity; Parkinson Disease; Radioimmunoassay; Tremor | 1993 |
Melatonin increases the in situ activity of tyrosine hydroxylase in the mediobasal hypothalamus of male Syrian hamsters.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Aromatic Amino Acid Decarboxylase Inhibitors; Cricetinae; Enzyme Inhibitors; Hydrazines; Hypothalamus, Middle; Levodopa; Male; Median Eminence; Melatonin; Mesocricetus; Reference Values; Time Factors; Tyrosine 3-Monooxygenase | 1996 |
Oxidative damage caused by free radicals produced during catecholamine autoxidation: protective effects of O-methylation and melatonin.
Topics: Catecholamines; Copper Sulfate; Deoxyepinephrine; Dopamine; Free Radicals; Levodopa; Melatonin; Methylation; Oxidation-Reduction; Phycoerythrin; Spectrometry, Fluorescence; Tyrosine | 1996 |
Hyperprolactinemia, a tool in treatment control of tetrahydrobiopterin deficiency: endocrine studies in an affected girl.
Topics: Adolescent; Biopterins; Carbidopa; Delayed-Action Preparations; Drug Combinations; Female; Follicle Stimulating Hormone; Human Growth Hormone; Humans; Hydrocortisone; Hyperprolactinemia; Insulin; Levodopa; Luteinizing Hormone; Melatonin; Phenylketonurias; Phosphorus-Oxygen Lyases; Prolactin | 1998 |
The effects of melatonin and L-DOPA on the diurnal rhythms of free amino acids content in the rat retina.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Lighting; Male; Melatonin; Rats; Rats, Wistar; Retina | 2000 |
Sodium nitroprusside stimulates L-DOPA release from striatal tissue through nitric oxide and cGMP.
Topics: Animals; Corpus Striatum; Cyclic GMP; Dose-Response Relationship, Drug; Levodopa; Male; Melatonin; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Salicylic Acid; Superoxide Dismutase; Uric Acid | 2002 |
Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster.
Topics: Animals; Antioxidants; Apoptosis; Brain; Cell Count; Dopamine; Dopamine Agonists; Drosophila melanogaster; Electron Transport Complex I; Insecticides; Levodopa; Locomotion; Melatonin; Nerve Degeneration; Neurons; Oxidative Stress; Parkinsonian Disorders; Phenotype; Rotenone | 2004 |
l-DOPA administration enhances 6-hydroxydopamine generation.
Topics: Animals; Antioxidants; Antiparkinson Agents; Ascorbic Acid; Corpus Striatum; Drug Interactions; Edetic Acid; Hydroxylation; Iron; Levodopa; Lipid Peroxidation; Male; Melatonin; Oxidopamine; Rats; Rats, Wistar | 2005 |
Endogenous melatonin protects L-DOPA from autoxidation in the striatal extracellular compartment of the freely moving rat: potential implication for long-term L-DOPA therapy in Parkinson's disease.
Topics: Animals; Ascorbic Acid; Corpus Striatum; Dopamine; Levodopa; Light; Male; Melatonin; Microdialysis; Movement; Oxidation-Reduction; Parkinson Disease; Quinones; Rats; Rats, Wistar | 2006 |
Tetrahydrobiopterin stimulates L-DOPA release from striatal tissue.
Topics: alpha-Methyltyrosine; Animals; Biopterins; Corpus Striatum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; In Vitro Techniques; Levodopa; Male; Melatonin; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Pterins; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2006 |
Melatonin: effects on dopaminergic and serotonergic neurons of the caudate nucleus of the striatum of male Syrian hamsters.
Topics: 5-Hydroxytryptophan; Animals; Caudate Nucleus; Circadian Rhythm; Cricetinae; Dopamine; Enzyme Inhibitors; Levodopa; Male; Melatonin; Mesocricetus; Neural Pathways; Neurons; Serotonin; Sex Factors; Synaptic Transmission; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 2007 |
Comment to the paper of Medeiros CAM, et al. (2007) J Neurol 254:459-464.
Topics: Antiparkinson Agents; Central Nervous System Depressants; Circadian Rhythm; Drug Administration Schedule; Drug Interactions; Humans; Levodopa; Melatonin; Parkinson Disease; Placebo Effect; Randomized Controlled Trials as Topic; Sleep; Sleep Wake Disorders; Time Factors | 2008 |
Effects of simulated hypo- and hyper-reproductive conditions on the characteristics of circadian rhythm in hypothalamic concentration of serotonin and dopamine and in plasma levels of thyroxine, triiodothyronine, and testosterone in Japanese quail, Coturn
Topics: 5-Hydroxytryptophan; Animals; Circadian Rhythm; Coturnix; Dopamine; Hypothalamus; Levodopa; Male; Melatonin; Pineal Gland; Reproduction; Serotonin; Testosterone; Thyroxine; Triiodothyronine | 2009 |
Reproductive responses and nitric oxide activity in Japanese quail, Coturnix coturnix japonica, are altered by specific phase relationships of neural (serotonergic and dopaminergic) oscillations and pineal function.
Topics: 5-Hydroxytryptophan; Animals; Biological Clocks; Cloaca; Coturnix; Dopamine; Levodopa; Male; Melatonin; Neurons; Nitrates; Nitric Oxide; Nitrites; Organ Size; Pineal Gland; Random Allocation; Serotonin; Spermatogenesis; Testosterone | 2009 |
Melatonin inhibits 6-hydroxydopamine production in the brain to protect against experimental parkinsonism in rodents.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Ascorbic Acid; Brain; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Ferrous Compounds; Levodopa; Male; Melatonin; Mice; Mice, Inbred BALB C; Oxidopamine; Parkinsonian Disorders | 2009 |
Sleep and rhythm consequences of a genetically induced loss of serotonin.
Topics: 5-Hydroxytryptophan; Adult; Alcohol Oxidoreductases; Antidepressive Agents, Second-Generation; Consanguinity; Disorders of Excessive Somnolence; Dopamine; Dopamine Agents; Drug Therapy, Combination; Humans; Hydrocortisone; Hyperphagia; Levodopa; Male; Melatonin; Polysomnography; Serotonin; Sleep; Sleep Disorders, Circadian Rhythm | 2010 |
Melatonin synergizes with low doses of L-DOPA to improve dendritic spine density in the mouse striatum in experimental Parkinsonism.
Topics: Animals; Antiparkinson Agents; Central Nervous System Depressants; Corpus Striatum; Dendrites; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Levodopa; Melatonin; Mice; Mice, Inbred BALB C; MPTP Poisoning; Parkinson Disease, Secondary | 2013 |
Antioxidant potential of melatonin enhances the response to L-dopa in 1-methyl 4-phenyl 1,2,3,6-tetrahydropyridine-parkinsonian mice.
Topics: Animals; Antioxidants; Antiparkinson Agents; Basal Ganglia; Behavior, Animal; Carbidopa; Catalase; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Glutathione Peroxidase; Levodopa; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Mice; Motor Activity; Oxidative Stress; Parkinsonian Disorders; Superoxide Dismutase | 2013 |
Disturbances in melatonin secretion and circadian sleep-wake regulation in Parkinson disease.
Topics: Actigraphy; Antiparkinson Agents; Case-Control Studies; Chronobiology Disorders; Female; Humans; Levodopa; Male; Melatonin; Middle Aged; Parkinson Disease; Polysomnography; Saliva | 2014 |
Melatonin enhances L-DOPA therapeutic effects, helps to reduce its dose, and protects dopaminergic neurons in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Dopaminergic Neurons; Drug Synergism; Levodopa; Male; Melatonin; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Parkinsonian Disorders; Substantia Nigra | 2015 |
Effect of melatonin on sleep disorders in a monkey model of Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Central Nervous System Depressants; Disease Models, Animal; Levodopa; Macaca fascicularis; Male; Melatonin; Parkinson Disease; Sleep Wake Disorders | 2015 |
Melatonin secretion in patients with Parkinson's disease receiving different-dose levodopa therapy.
Topics: Aged; Antiparkinson Agents; Circadian Rhythm; Cross-Sectional Studies; Humans; Levodopa; Melatonin; Parkinson Disease | 2020 |