melatonin has been researched along with kainic acid in 51 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 22 (43.14) | 18.2507 |
| 2000's | 19 (37.25) | 29.6817 |
| 2010's | 7 (13.73) | 24.3611 |
| 2020's | 3 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Iuvone, PM; Zawilska, JB | 1 |
| Mitchell, CK; Redburn, DA | 1 |
| Chen, LD; Melchiorri, D; Nisticó, G; Reiter, RJ; Sewerynek, E | 2 |
| Giusti, P; Gusella, M; Lipartiti, M; Manev, H; Milani, D; Vicini, S; Zhu, W | 1 |
| Iuvone, PM; Thomas, KB; Tigges, M | 1 |
| Floreani, M; Franceschini, D; Giusti, P; Lipartiti, M; Manev, H; Schiavo, N | 1 |
| Franceschini, D; Giusti, P; Kharlamov, A; Manev, H; Uz, T | 1 |
| Floreani, M; Franceschini, D; Giusti, P; Manev, H; Petrone, M | 1 |
| Cagnoli, CM; Franceschini, D; Giusti, P; Gusella, M; Kharlamov, A; Lipartiti, M; Manev, H; Zanoni, R | 1 |
| Joo, JY; Kharlamov, A; Manev, H; Uz, T | 1 |
| Cazevieille, C; Osborne, NN | 1 |
| Giusti, P; Manev, H; Uz, T | 1 |
| Facci, L; Floreani, M; Giusti, P; Lipartiti, M; Skaper, SD | 1 |
| Garcia, JJ; Li, ZR; Ortiz, GG; Reiter, RJ; Tang, L; Yu, BP | 1 |
| Lapin, IP; Mirzaev, SM; Oxenkrug, GF; Ryzov, IV | 1 |
| Bernard, M; Cassone, VM; Chong, NW; Iuvone, PM; Klein, DC | 1 |
| El-Sokkary, GH; Kim, SJ; Manchester, LC; Qi, W; Reiter, RJ; Tan, DX | 1 |
| Chen, ST; Chuang, JI | 1 |
| Alonso-Gómez, AL; Iuvone, PM; Valenciano, AI | 1 |
| Ceccon, M; Facci, L; Floreani, M; Giusti, P; Skaper, SD | 1 |
| Borin, G; Floreani, M; Franceschini, D; Giusti, P; Skaper, SD | 1 |
| Huh, SO; Kim, YH; Song, DK; Suh, HW; Won, JS | 1 |
| Kim, CY; Lee, SR; Lee, YK | 1 |
| Chang, YH; Chen, ST; Chuang, JI; Jen, LS | 1 |
| Dabbeni-Sala, F; Floreani, M; Franceschini, D; Giusti, P; Skaper, SD | 1 |
| Beas-Zárate, C; Benítez-King, G; Ortiz, GG; Reiter, RJ; Sánchez-Ruiz, Y; Tan, DX | 1 |
| Mohanan, PV; Yamamoto, HA | 3 |
| Chung, SY; Han, SH | 1 |
| Ananth, C; Gopalakrishnakone, P; Kaur, C | 1 |
| Kanit, L; Sozmen, EY; Yalcin, A | 1 |
| Liu, C; Sakamoto, K; Tosini, G | 1 |
| Kilinc, E; Kocturk, S; Resmi, H; Sozmen, EY; Yalcin, A | 1 |
| Akcay, YD; Sozmen, EY; Yalcin, A | 1 |
| Jang, YH; Lee, H; Lee, SR | 1 |
| Cho, BP; Chun, W; Han, JA; Kim, SS; Kong, PJ; Kwon, OY; Lee, HJ; Lee, SH | 1 |
| Costa, LG; Giordano, G; Kavanagh, TJ; Mohar, I; White, CC | 1 |
| Hille, B; Kim, MH; Koh, DS; Moriyama, Y; Muroyama, A; Uehara, S | 1 |
| Chang, CF; Huang, HJ; Hung, KC; Lee, HC; Lin, AM; Wu, RT | 1 |
| Bhatnagar, M; Jain, A; Sharma, D; Suhalka, P; Sukhwal, P | 1 |
| Atanasova, D; Kortenska, L; Lazarov, N; Lozanov, V; Mitreva, R; Moyanova, S; Pechlivanova, D; Petkova, Z; Stoynev, A; Tchekalarova, J | 1 |
| Atanasova, M; Blazhev, A; Dragomirova, P; Pechlivanova, D; Petkova, Z; Tchekalarova, J | 1 |
| Atanasova, D; Kortenska, L; Lazarov, N; Lozanov, V; Markova, P; Mitreva, R; Moyanova, S; Pechlivanova, D; Petkova, Z; Popov, D; Stoynev, A; Tchekalarova, J | 1 |
| Kim, HA; Lee, BH; Lee, KH | 1 |
| Ábrahám, IM; Cho, DH; Han, SK; Jang, SH; Park, SA; Rijal, S | 1 |
| Andreeva-Gateva, P; Angelova, V; Stoyanova, T; Tchekalarova, J; Tzoneva, R | 1 |
| Baldin, SL; Bernardo, HT; de Farias, ACS; de Pieri Pickler, K; Dondossola, ER; Rico, EP | 1 |
4 review(s) available for melatonin and kainic acid
| Article | Year |
|---|---|
Neuroprotective effects of melatonin.
Topics: Animals; Brain; Cell Death; Cerebellum; Hippocampus; Humans; Kainic Acid; Melatonin; Neurons; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Rats | 1996 |
Neuroprotective action of the pineal hormone melatonin against excitotoxicity. Receptor abuse-dependent antagonism (RADA).
Topics: Animals; Cerebrovascular Disorders; Glutamic Acid; Humans; Kainic Acid; Melatonin; Neuroprotective Agents; Neurotoxins; Pineal Gland; Rats; Receptors, Glutamate | 1997 |
Excitotoxicity, oxidative stress, and the neuroprotective potential of melatonin.
Topics: Animals; Antioxidants; Excitatory Amino Acid Agonists; Glutathione; Kainic Acid; Melatonin; Neurotoxins; Oxidative Stress; Rats; Reactive Oxygen Species | 1999 |
Further evidences for neuroprotective effects of melatonin.
Topics: Animals; Astrocytes; Brain; Free Radical Scavengers; Glutathione; Glutathione Reductase; Humans; Kainic Acid; Melatonin; Neurons; Neuroprotective Agents; Rats | 1999 |
47 other study(ies) available for melatonin and kainic acid
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Melatonin synthesis in chicken retina: effect of kainic acid-induced lesions on the diurnal rhythm and D2-dopamine receptor-mediated regulation of serotonin N-acetyltransferase activity.
Topics: Animals; Arylamine N-Acetyltransferase; Chickens; Circadian Rhythm; Darkness; Dopamine Agents; Ergolines; Homeostasis; Kainic Acid; Light; Male; Melatonin; Quinpirole; Receptors, Dopamine; Receptors, Dopamine D2; Reference Values; Retina | 1992 |
Melatonin inhibits ACh release from rabbit retina.
Topics: Acetylcholine; Animals; Dark Adaptation; Kainic Acid; Melatonin; Photic Stimulation; Potassium; Rabbits; Retina; Synaptosomes | 1991 |
Melatonin reduces kainate-induced lipid peroxidation in homogenates of different brain regions.
Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Hippocampus; Kainic Acid; Lipid Peroxidation; Male; Melatonin; Rats; Rats, Sprague-Dawley; Rats, Wistar | 1995 |
Melatonin protects primary cultures of cerebellar granule neurons from kainate but not from N-methyl-D-aspartate excitotoxicity.
Topics: Animals; Cerebellum; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Melatonin; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats | 1995 |
Melatonin synthesis and circadian tryptophan hydroxylase activity in chicken retina following destruction of serotonin immunoreactive amacrine and bipolar cells by kainic acid.
Topics: 5-Hydroxytryptophan; Animals; Chickens; Circadian Rhythm; Dopamine; In Vitro Techniques; Kainic Acid; Male; Melatonin; Neurons; Retina; Serotonin; Tryptophan; Tryptophan Hydroxylase | 1993 |
Neuroprotection by melatonin from kainate-induced excitotoxicity in rats.
Topics: Animals; Antioxidants; Behavior, Animal; Brain; Kainic Acid; Male; Melatonin; Rats; Rats, Wistar | 1996 |
Protective effect of melatonin against hippocampal DNA damage induced by intraperitoneal administration of kainate to rats.
Topics: Animals; Cell Count; DNA; Hippocampus; Kainic Acid; Male; Melatonin; Rats; Rats, Wistar | 1996 |
Melatonin affords protection against kainate-induced in vitro lipid peroxidation in brain.
Topics: Animals; Brain; Excitatory Amino Acid Agonists; In Vitro Techniques; Kainic Acid; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 1996 |
In vitro and in vivo protection against kainate-induced excitotoxicity by melatonin.
Topics: Animals; Ascorbic Acid; Brain; Brain Diseases; Dose-Response Relationship, Drug; Ferric Compounds; Kainic Acid; Lipid Peroxidation; Male; Melatonin; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Synaptosomes | 1996 |
Increased brain damage after stroke or excitotoxic seizures in melatonin-deficient rats.
Topics: Animals; Brain; Cerebrovascular Disorders; Kainic Acid; Male; Melatonin; Neuroprotective Agents; Pineal Gland; Rats; Rats, Sprague-Dawley; Seizures | 1996 |
Retinal neurones containing kainate receptors are influenced by exogenous kainate and ischaemia while neurones lacking these receptors are not -- melatonin counteracts the effects of ischaemia and kainate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Excitatory Amino Acid Antagonists; Ischemia; Kainic Acid; Melatonin; Neurons; Rabbits; Receptors, Kainic Acid; Retina; Retinal Vessels | 1997 |
Melatonin maintains glutathione homeostasis in kainic acid-exposed rat brain tissues.
Topics: Animals; Brain; Cerebellum; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Homeostasis; In Vitro Techniques; Kainic Acid; Kinetics; Male; Melatonin; Neurons; Neuroprotective Agents; Prosencephalon; Rats; Rats, Wistar; Reactive Oxygen Species; Tissue Distribution | 1997 |
Melatonin reduces the increase in 8-hydroxy-deoxyguanosine levels in the brain and liver of kainic acid-treated rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Brain; Deoxyguanosine; DNA Damage; Kainic Acid; Liver; Male; Melatonin; Oxidative Stress; Rats; Rats, Sprague-Dawley | 1998 |
Anticonvulsant activity of melatonin against seizures induced by quinolinate, kainate, glutamate, NMDA, and pentylenetetrazole in mice.
Topics: Animals; Anticonvulsants; Brain; Convulsants; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Injections, Intraperitoneal; Injections, Intraventricular; Kainic Acid; Male; Melatonin; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Pentylenetetrazole; Quinolinic Acid; Seizures | 1998 |
Circadian expression of tryptophan hydroxylase mRNA in the chicken retina.
Topics: Animals; Chickens; Circadian Rhythm; Darkness; In Situ Hybridization; Kainic Acid; Light; Male; Melatonin; Photoreceptor Cells; Pineal Gland; Retina; Retinal Ganglion Cells; RNA, Messenger; Tryptophan Hydroxylase | 1998 |
Melatonin protects hippocampal neurons in vivo against kainic acid-induced damage in mice.
Topics: Animals; Cell Membrane; Cell Nucleus; Kainic Acid; Lipid Peroxidation; Male; Melatonin; Mice; Nervous System Diseases; Neuroprotective Agents; Pyramidal Cells; Random Allocation | 1998 |
The antioxidant melatonin reduces cortical neuronal death after intrastriatal injection of kainate in the rat.
Topics: Animals; Antioxidants; Apoptosis; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Agonists; Glutathione; Glutathione Peroxidase; In Situ Nick-End Labeling; Kainic Acid; Male; Melatonin; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley | 1999 |
Diurnal rhythms of tryptophan hydroxylase activity in Xenopus laevis retina: opposing phases in photoreceptors and inner retinal neurons.
Topics: Analysis of Variance; Animals; Circadian Rhythm; Kainic Acid; Male; Melatonin; Neurons; Photoreceptor Cells, Vertebrate; Retina; Tryptophan Hydroxylase; Xenopus laevis | 1999 |
Effect of melatonin on the regulation of proenkephalin and prodynorphin mRNA levels induced by kainic acid in the rat hippocampus.
Topics: Animals; Enkephalins; Gene Expression Regulation; Genes, fos; Hippocampus; Injections, Intraperitoneal; Kainic Acid; Kinetics; Male; Melatonin; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Transcription Factor AP-1; Transcription, Genetic | 2000 |
Melatonin attenuates the changes in polyamine levels induced by systemic kainate administration in rat brains.
Topics: Animals; Brain; Cerebral Cortex; Chromatography, High Pressure Liquid; Hippocampus; Kainic Acid; Male; Melatonin; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Seizures; Spermidine; Spermine | 2000 |
Alteration of Bcl-2 expression in the nigrostriatal system after kainate injection with or without melatonin co-treatment.
Topics: Actins; Animals; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Antioxidants; Avian Proteins; Basigin; Blood Proteins; Corpus Striatum; Excitatory Amino Acid Agonists; Kainic Acid; Male; Melatonin; Membrane Glycoproteins; Microglia; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase | 2001 |
Kainic acid induces selective mitochondrial oxidative phosphorylation enzyme dysfunction in cerebellar granule neurons: protective effects of melatonin and GSH ethyl ester.
Topics: Animals; Antioxidants; Cell Survival; Cerebellum; Electron Transport Complex II; Glutathione; Kainic Acid; Melatonin; Mitochondria; Multienzyme Complexes; Neurons; Oxidative Phosphorylation; Oxidoreductases; Rats; Reactive Oxygen Species; Succinate Dehydrogenase | 2001 |
Melatonin, vitamin E, and estrogen reduce damage induced by kainic acid in the hippocampus: potassium-stimulated GABA release.
Topics: Animals; Antioxidants; Estradiol; Free Radical Scavengers; gamma-Aminobutyric Acid; Hippocampus; Kainic Acid; Male; Melatonin; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Potassium; Vitamin E | 2001 |
Preventive effect of melatonin against DNA damage induced by cyanide, kainate, glutathione/Fe(3+)/O(2), or H(2)O(2)/Fe(2+).
Topics: Animals; Brain; DNA; DNA Damage; Dose-Response Relationship, Drug; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; Iron; Kainic Acid; Lipid Peroxidation; Male; Melatonin; Mice; Mice, Inbred Strains; Potassium Cyanide | 2001 |
Preventive effect of melatonin against brain mitochondria DNA damage, lipid peroxidation and seizures induced by kainic acid.
Topics: Animals; Brain; DNA Damage; DNA, Mitochondrial; Free Radical Scavengers; Hydroxyl Radical; Kainic Acid; Lipid Peroxidation; Male; Melatonin; Mice; Seizures | 2002 |
Melatonin attenuates kainic acid-induced hippocampal neurodegeneration and oxidative stress through microglial inhibition.
Topics: Animals; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Kainic Acid; Male; Melatonin; Microglia; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2003 |
Ganglioside GT1B and melatonin inhibit brain mitochondrial DNA damage and seizures induced by kainic acid in mice.
Topics: Animals; Brain; Cell Death; DNA Damage; DNA, Mitochondrial; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Free Radicals; Gangliosides; Kainic Acid; Male; Melatonin; Mice; Mitochondria; Neurons; Oxidative Stress | 2003 |
Protective role of melatonin in domoic acid-induced neuronal damage in the hippocampus of adult rats.
Topics: Animals; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Astrocytes; Avian Proteins; Basigin; Blood Proteins; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Kainic Acid; Male; Melatonin; Membrane Glycoproteins; Microglia; Microscopy, Electron; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Nitric Oxide Synthase; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Kainic Acid; RNA, Messenger | 2003 |
Altered gene expressions in rat hippocampus after kainate injection with or without melatonin pre-treatment.
Topics: Animals; Gene Expression Regulation; Hippocampus; Kainic Acid; Male; Melatonin; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2004 |
Circadian rhythms in the retina of rats with photoreceptor degeneration.
Topics: Animals; Arylamine N-Acetyltransferase; Circadian Rhythm; Disease Models, Animal; Excitatory Amino Acid Agonists; Kainic Acid; Melatonin; Photoreceptor Cells, Vertebrate; Rats; Retina; Retinal Degeneration; RNA, Messenger | 2004 |
Effect of melatonin cotreatment against kainic acid on coenzyme Q10, lipid peroxidation and Trx mRNA in rat hippocampus.
Topics: Animals; Antioxidants; Coenzymes; Drug Interactions; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Agonists; Gene Expression; Hippocampus; Kainic Acid; Lipid Peroxidation; Male; Melatonin; Neurotoxins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thioredoxins; Ubiquinone | 2004 |
The effect of melatonin on lipid peroxidation and nitrite/nitrate levels, and on superoxide dismutase and catalase activities in kainic acid-induced injury.
Topics: Animals; Brain Diseases; Catalase; Kainic Acid; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Nitrates; Nitrites; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2005 |
Protective effect of propofol against kainic acid-induced lipid peroxidation in mouse brain homogenates: comparison with trolox and melatonin.
Topics: Anesthetics, Intravenous; Animals; Antioxidants; Brain Chemistry; Chromans; Excitatory Amino Acid Antagonists; Ferrous Compounds; Hydrogen Peroxide; In Vitro Techniques; Kainic Acid; Lipid Peroxidation; Male; Melatonin; Mice; Mice, Inbred ICR; Propofol; Quaternary Ammonium Compounds; Thiobarbituric Acid Reactive Substances | 2005 |
Sustained activation of Akt by melatonin contributes to the protection against kainic acid-induced neuronal death in hippocampus.
Topics: Animals; Astrocytes; Cell Death; Enzyme Activation; Glial Cell Line-Derived Neurotrophic Factor; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Melatonin; Mice; Mice, Inbred ICR; Neurons; Nitric Oxide Synthase Type II; Proto-Oncogene Proteins c-akt | 2006 |
Glutathione levels modulate domoic acid induced apoptosis in mouse cerebellar granule cells.
Topics: Animals; Antioxidants; Apoptosis; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Drug Antagonism; Enzymes; Gene Silencing; Glutamate-Cysteine Ligase; Glutathione; Kainic Acid; Melatonin; Membrane Potential, Mitochondrial; Mice; Mice, Knockout; Mitochondria; Neurons; Neurotoxins; Reactive Oxygen Species | 2007 |
Glutamate transporter-mediated glutamate secretion in the mammalian pineal gland.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cesium; Chlorides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Exocytosis; Glutamic Acid; In Vitro Techniques; Kainic Acid; Macrolides; Magnesium; Male; Melatonin; Membrane Potentials; Pineal Gland; Potassium Chloride; Rats; Rats, Sprague-Dawley | 2008 |
Melatonin attenuates kainic acid-induced neurotoxicity in mouse hippocampus via inhibition of autophagy and α-synuclein aggregation.
Topics: alpha-Synuclein; Animals; Autophagy; Base Sequence; Hippocampus; Immunoprecipitation; Kainic Acid; Melatonin; Mice; RNA, Small Interfering | 2012 |
Changes in the density of nitrergic neurons in the hippocampus of rats following kainic acid and melatonin administration.
Topics: Animals; Behavior, Animal; Calcium; Cell Count; Excitatory Amino Acid Agonists; Female; Free Radical Scavengers; Hippocampus; Immunohistochemistry; Kainic Acid; Melatonin; NADPH Dehydrogenase; Neurons; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar | 2013 |
Prophylactic treatment with melatonin after status epilepticus: effects on epileptogenesis, neuronal damage, and behavioral changes in a kainate model of temporal lobe epilepsy.
Topics: Analysis of Variance; Animals; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Depression; Electroencephalography; Excitatory Amino Acid Agonists; Exploratory Behavior; Hippocampus; Hyperkinesis; Kainic Acid; Kaplan-Meier Estimate; Male; Maze Learning; Melatonin; Neurons; Rats; Rats, Wistar; Serotonin; Status Epilepticus; Sucrose; Swimming; Time Factors | 2013 |
Strain-dependent effects of long-term treatment with melatonin on kainic acid-induced status epilepticus, oxidative stress and the expression of heat shock proteins.
Topics: Animals; Blotting, Western; Cytosol; Heat-Shock Proteins; Kainic Acid; Male; Melatonin; Mitochondria; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Wistar; Species Specificity; Status Epilepticus; Superoxide Dismutase | 2013 |
Treatment with melatonin after status epilepticus attenuates seizure activity and neuronal damage but does not prevent the disturbance in diurnal rhythms and behavioral alterations in spontaneously hypertensive rats in kainate model of temporal lobe epile
Topics: Animals; Antioxidants; Behavior, Animal; Blood Pressure; Body Weight; Brain; Circadian Rhythm; Disease Models, Animal; Epilepsy, Temporal Lobe; Exploratory Behavior; Food Preferences; Kainic Acid; Male; Maze Learning; Melatonin; Rats; Rats, Inbred SHR; Serotonin; Swimming; Time Factors | 2014 |
Neuroprotective effect of melatonin against kainic acid-induced oxidative injury in hippocampal slice culture of rats.
Topics: Animals; Antioxidants; Arachidonate 5-Lipoxygenase; Caspase 3; Cell Death; Dose-Response Relationship, Drug; Hippocampus; Kainic Acid; Melatonin; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2014 |
Melatonin Suppresses the Kainate Receptor-Mediated Excitation on Gonadotropin-Releasing Hormone Neurons in Female and Male Prepubertal Mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Excitatory Amino Acid Agonists; Female; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; Kainic Acid; Male; Melatonin; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neurons; Pertussis Toxin; Puberty; Receptors, Kainic Acid | 2020 |
The Anticonvulsant Effect of a Novel Indole-Related Compound in the Kainate-Induced Status Epilepticus in Mice: The Role of the Antioxidant and Anti-inflammatory Mechanism.
Topics: Animals; Anti-Inflammatory Agents; Anticonvulsants; Antioxidants; Hippocampus; Kainic Acid; Melatonin; Mice; Oxidative Stress; Status Epilepticus | 2022 |
Melatonin Pretreatment Protects Against Status epilepticus, Glutamate Transport, and Oxidative Stress Induced by Kainic Acid in Zebrafish.
Topics: Amino Acid Transport System X-AG; Animals; Antioxidants; Catalase; Glutamic Acid; Glutathione; Kainic Acid; Melatonin; Neurons; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Status Epilepticus; Superoxide Dismutase; Zebrafish | 2022 |