melatonin has been researched along with indomethacin in 62 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (11.29) | 18.7374 |
| 1990's | 4 (6.45) | 18.2507 |
| 2000's | 30 (48.39) | 29.6817 |
| 2010's | 19 (30.65) | 24.3611 |
| 2020's | 2 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Cha, SH; Endou, H; Kanai, Y; Kojima, R; Kusuhara, H; Sekine, T; Sugiyama, Y; Tsuda, M; Utsunomiya-Tate, N | 1 |
| Glabe, CG; Kayed, R; Milton, S; Necula, M | 1 |
| Abdel-Salam, OM; Baiuomy, AR; Elmegeed, GA | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG | 1 |
| Gestwicki, JE; Reinke, AA; Seh, HY | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Baudy-Floc'h, M; Bi, L; Bi, W; Bi, Y; Gao, X; Gibson, KM; Li, M; Ngerebara, N; Wang, Z; Xue, P; Zhang, Y | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Levine, L; Riceberg, LJ | 1 |
| Kogo, H; Tamura, K | 1 |
| Bird, H; Okala, B; Othman, H; Padwick, DJ; Smith, JA; Surrall, K | 1 |
| Cardinali, DP; Gimeno, AL; Gimeno, MF; Landa, A; Sterin-Speziale, N | 1 |
| Cardinali, DP; Pereyra, E; Rita, MN; Solveyra, CG | 1 |
| Leach, CM; Thorburn, GD | 1 |
| Cardinali, DP; Ritta, MN | 1 |
| Arakawa, Y; Asai, S; Ishikawa, K; Iwasaki, A; Kaneda, N; Kato, K; Komuro, S; Kuwayama, H; Matsuno, Y; Murai, I; Nakagawa, S | 1 |
| Alarcón de la Lastra, C; Barranco, MD; Cabeza, J; Herrerías, JM; Martín, MJ; Motilva, V; Nieto, A | 1 |
| Agrewala, JN; Kulkarni, SK; Raghavendra, V | 1 |
| Bandyopadhyay, D; Bandyopadhyay, U; Banerjee, RK; Biswas, K; Reiter, RJ | 1 |
| Fukaya, T; Okatani, Y; Taniguchi, K; Wakatsuki, A; Watanabe, K | 1 |
| Dodick, DW | 1 |
| Adámeková, E; Ahlers, I; Ahlersová, E; Bojková, B; Kubatka, P; M ciková-Kalická, K; Mníchová-Chamilová, M | 1 |
| Oshinsky, M; Peres, MF; Rozen, TD; Stiles, MA | 1 |
| Ayar, A; Kelestimur, H; Kutlu, S; Yilmaz, B | 1 |
| Amer, MA; El-Missiry, MA; Othman, AI | 1 |
| Abdel-Salam, OM; Arbid, MS; Baiuomy, AR; El-Batran, S; El-Shenawy, SM | 1 |
| Anzenbacher, P; Grossmann, V; Smetanová, L; Stetinová, V | 1 |
| Adámeková, E; Ahlers, I; Ahlersová, E; Bojková, B; Chamilová, M; Kalická, K; Kubatka, P | 1 |
| Bhargava, VK; Garg, SK; Singh, P | 1 |
| Rozen, TD | 1 |
| Abdel-Salam, OM; Arbid, MS; Baiuomy, AR | 1 |
| Hemieda, FA | 1 |
| Badawy, ME; El-Missiry, MA; Goda, AA; Hemieda, FA | 1 |
| Ganguly, K; Maity, P; Reiter, RJ; Swarnakar, S | 1 |
| Brzozowska, I; Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Pawlik, M; Pawlik, WW; Sliwowski, Z; Zwirska-Korczala, K | 1 |
| Banerjee, A; Ganguly, K; Kundu, P; Reiter, RJ; Swarnakar, S | 1 |
| Elkashef, HA; Kafl, HE | 1 |
| Ghazi-Khansari, M; Kiarostami, V; Samini, L | 1 |
| Byrns, MC; Penning, TM; Steckelbroeck, S | 1 |
| Aguilar, CF; de la Rocha, N; Pelzer, L; Rotelli, A | 1 |
| Alam, A; Bandyopadhyay, U; Bindu, S; Dey, S; Goyal, M; Maity, P; Pal, C; Reiter, R | 1 |
| Antonioli, L; Blandizzi, C; Colucci, R; Del Tacca, M; Fornai, M; Ghisu, N; Tuccori, M | 1 |
| Ganguly, K; Swarnakar, S | 2 |
| Ferrante, E; Lisotto, C; Nappi, G; Rossi, P; Tassorelli, C | 1 |
| Ganguly, K; Reiter, RJ; Sharma, AV; Swarnakar, S | 1 |
| Holle, D; Obermann, M | 1 |
| Pradeepkumar Singh, L; Swarnakar, S; Vivek Sharma, A | 1 |
| Arruda, MA; Bigal, ME; Bonamico, L; Bordini, CA; Stella, C | 1 |
| Malinin, VV; Savateeva-Liubimova, TN; Sivak, KV | 1 |
| Ahlers, I; Ahlersová, E; Bojková, B; Kalická, K; Kubatka, P; Péč, M | 1 |
| Barlow, KM; Bodell, L; Crawford, S; Dewey, D; Kuczynski, A | 1 |
| Hollingworth, M; Young, TM | 1 |
| Beams, JL; Rozen, TD | 1 |
| McNally, MA; Soul, JS | 1 |
| Dilli, E; Murray, D | 1 |
| Abbasinazari, M; Abdi, S; Asadzadeh Aghdaei, H; Hatami, B; Jamshidzadeh, S; Rasoolinezhad, M; Saadati, S; Sadeghi, A | 1 |
| Burish, MJ; Rozen, TD | 1 |
| Chatterjee, A; Choudhary, P; Mishra, VK; Pant, S; Roy, T; Swarnakar, S | 1 |
| Du, F; Fan, H; Ren, L; Yang, X; Yuan, W; Zhang, L; Zhang, Y | 1 |
6 review(s) available for melatonin and indomethacin
| Article | Year |
|---|---|
Focus on therapy of primary stabbing headache.
Topics: Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders, Primary; Humans; Indomethacin; Melatonin; Ophthalmic Nerve; Treatment Outcome | 2010 |
Hypnic headache.
Topics: Antidepressive Agents; Caffeine; Central Nervous System Stimulants; Cyclooxygenase Inhibitors; Headache Disorders, Primary; Humans; Indomethacin; Melatonin | 2010 |
Pharmacologic Prevention and Treatment of Neonatal Brain Injury.
Topics: Adrenal Cortex Hormones; Allopurinol; Anesthetics, Inhalation; Anticonvulsants; Antioxidants; Cerebral Intraventricular Hemorrhage; Cyclooxygenase Inhibitors; Darbepoetin alfa; Erythropoietin; Free Radical Scavengers; Hematinics; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Indomethacin; Infant, Newborn; Leukomalacia, Periventricular; Magnesium; Melatonin; Neuroprotection; Prenatal Care; Topiramate; Xenon | 2019 |
Primary Stabbing Headache.
Topics: Comorbidity; Diagnosis, Differential; Female; Headache Disorders, Primary; Humans; Indomethacin; Male; Melatonin; Migraine Disorders; Neuroimaging; Pain; Prevalence; Prospective Studies | 2019 |
Trigeminal Autonomic Cephalalgias.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Headache; Humans; Hypothalamus; Indomethacin; Lithium Carbonate; Melatonin; Trigeminal Autonomic Cephalalgias; Vagus Nerve | 2019 |
Efficacy of Combined Management with Nonsteroidal Anti-inflammatory Drugs for Prevention of Pancreatitis After Endoscopic Retrograde Cholangiography: a Bayesian Network Meta-analysis.
Topics: Administration, Rectal; Anti-Inflammatory Agents, Non-Steroidal; Cholangiopancreatography, Endoscopic Retrograde; Diclofenac; Epinephrine; Humans; Indomethacin; Melatonin; Network Meta-Analysis; Nitrates; Nitroglycerin; Pancreatitis; Somatostatin; Systematic Reviews as Topic | 2022 |
56 other study(ies) available for melatonin and indomethacin
| Article | Year |
|---|---|
Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain.
Topics: Amino Acid Sequence; Animals; Brain; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Estrone; Molecular Sequence Data; Ochratoxins; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Xenopus laevis | 1999 |
Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Humans; Plaque, Amyloid; Protein Structure, Quaternary; Thermodynamics | 2007 |
Evaluation of the anti-inflammatory and anti-nociceptive activities of novel synthesized melatonin analogues.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Edema; Extremities; Melatonin; Mice; Molecular Structure; Rats | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship | 2008 |
A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.
Topics: Amyloid beta-Peptides; Benzothiazoles; Coloring Agents; Congo Red; Fluorescent Dyes; Indoles; Spectrometry, Fluorescence; Thiazoles | 2009 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Synthesis and characterization of novel indole derivatives reveal improved therapeutic agents for treatment of ischemia/reperfusion (I/R) injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Capillary Permeability; Free Radical Scavengers; Hindlimb; Indoles; Inflammation; Lipid Peroxidation; Lung Injury; Mice; Muscle, Skeletal; PC12 Cells; Rats; Reperfusion Injury; Structure-Activity Relationship | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Radioimmunoassay for melatonin.
Topics: 5-Methoxytryptamine; Animals; Antigen-Antibody Reactions; Humans; Immunization; Immunoglobulin G; Indoles; Indomethacin; Melatonin; Methods; Rabbits; Radioimmunoassay; Serum Albumin | 1975 |
The mode of action of indomethacin, aspirin and melatonin on the blockage of the first ovulation in immature rat pretreated with PMSG.
Topics: Animals; Aspirin; Chorionic Gonadotropin; Dinoprost; Female; Gonadotropins; Gonadotropins, Equine; Indomethacin; Melatonin; Ovulation; Rats; Rats, Inbred Strains | 1989 |
Effect of ibuprofen and indomethacin on human plasma melatonin.
Topics: Adult; Delayed-Action Preparations; Humans; Ibuprofen; Indomethacin; Male; Melatonin | 1987 |
Melatonin blocks in vitro generation of prostaglandin by the uterus and hypothalamus.
Topics: Animals; Castration; Female; Hypothalamus; In Vitro Techniques; Indomethacin; Luteinizing Hormone; Melatonin; Neurotransmitter Agents; Oxytocin; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Uterine Contraction; Uterus | 1980 |
Role of prostaglandins in rat pineal neuroeffector junction. Changes in melatonin and norepinephrine release in vitro.
Topics: Alprostadil; Animals; Aspirin; Dinoprost; Dinoprostone; Indomethacin; Male; Mefenamic Acid; Melatonin; Norepinephrine; Pineal Gland; Potassium; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains | 1982 |
A comparison of the inhibitory effects of melatonin and indomethacin on platelet aggregation and thromboxane release.
Topics: Arachidonic Acids; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Humans; Indomethacin; Melatonin; Platelet Aggregation; Thromboxanes | 1980 |
Effect of indomethacin on monoamine metabolism and melatonin synthesis in rat pineal gland.
Topics: Acetylserotonin O-Methyltransferase; Animals; Biogenic Amines; Indomethacin; Male; Melatonin; Monoamine Oxidase; Pineal Gland; Prostaglandin Antagonists; Prostaglandins; Rats | 1980 |
Protective role of melatonin and the pineal gland in modulating water immersion restraint stress ulcer in rats.
Topics: Animals; Cyclooxygenase Inhibitors; Free Radical Scavengers; Indomethacin; Male; Melatonin; Pineal Gland; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stomach Ulcer; Stress, Physiological | 1998 |
Protective effect of melatonin on indomethacin-induced gastric injury in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Free Radical Scavengers; Gastric Mucosa; Glutathione Peroxidase; Indomethacin; Lipid Peroxidation; Male; Melatonin; Neutrophils; Peroxidase; Rats; Rats, Wistar; Stomach Ulcer; Thiobarbituric Acid Reactive Substances | 1999 |
Role of centrally administered melatonin and inhibitors of COX and NOS in LPS-induced hyperthermia and adipsia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Cyclooxygenase Inhibitors; Dinoprostone; Fever; Indomethacin; Lipopolysaccharides; Male; Melatonin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Sulfonamides; Thirst; Time Factors | 1999 |
Melatonin protects against stress-induced gastric lesions by scavenging the hydroxyl radical.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Cold Temperature; Dose-Response Relationship, Drug; Free Radical Scavengers; Hydroxyl Radical; Indomethacin; Lipid Peroxidation; Melatonin; Omeprazole; Peptic Ulcer; Ranitidine; Rats; Rats, Wistar; Stress, Physiological | 2000 |
Melatonin suppresses lysophosphatidylcholine enhancement of serotonin-induced vasoconstriction in the human umbilical artery.
Topics: Adult; Dose-Response Relationship, Drug; Drug Synergism; Female; Free Radical Scavengers; Humans; Indomethacin; Lysophosphatidylcholines; Mannitol; Melatonin; Muscle, Smooth, Vascular; omega-N-Methylarginine; Pregnancy; Serotonin; Umbilical Arteries; Vasoconstriction | 2000 |
Polysomnography in hypnic headache syndrome.
Topics: Aged; Female; Headache; Humans; Indomethacin; Male; Melatonin; Middle Aged; Polysomnography; Recurrence; Sleep; Sleep Apnea, Obstructive; Sleep, REM; Syndrome | 2000 |
Preventive effect of indomethacin and melatonin on 7, 12-dimethybenz/a/anthracene-induced mammary carcinogenesis in female Sprague-Dawley rats. A preliminary report.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Female; Indomethacin; Mammary Neoplasms, Experimental; Melatonin; Rats; Rats, Sprague-Dawley | 2001 |
Remitting form of hemicrania continua with seasonal pattern.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Headache Disorders; Humans; Indomethacin; Melatonin; Middle Aged; Recurrence; Remission, Spontaneous; Seasons | 2001 |
Melatonin inhibits spontaneous and oxytocin-induced contractions of rat myometrium in vitro.
Topics: Animals; Apamin; Calcium; Cyclooxygenase Inhibitors; Dinoprost; Female; In Vitro Techniques; Indomethacin; Melatonin; Oxytocin; Potassium Channels; Potassium Chloride; Pregnancy; Rats; Rats, Wistar; Solutions; Uterine Contraction | 2001 |
The protective action of melatonin on indomethacin-induced gastric and testicular oxidative stress in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cytosol; Gastric Mucosa; Hydroxyl Radical; Indomethacin; Isoenzymes; L-Lactate Dehydrogenase; Lipid Peroxidation; Lipoxygenase; Male; Melatonin; Mitochondria; Oxidation-Reduction; Oxidative Stress; Rats; Superoxide Dismutase; Testis; Thiobarbituric Acid Reactive Substances | 2001 |
Studies on the anti-inflammatory and anti-nociceptive effects of melatonin in the rat.
Topics: Administration, Topical; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase Inhibitors; Cysteamine; Edema; Hindlimb; Indomethacin; Inflammation; Injections, Intraperitoneal; Lactones; Male; Melatonin; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Sulfones; Tail | 2002 |
In vitro and in vivo assessment of the antioxidant activity of melatonin and related indole derivatives.
Topics: Alloxan; Animals; Antioxidants; Carboxylic Acids; Female; Hyaluronic Acid; Hyperglycemia; In Vitro Techniques; Indoles; Indomethacin; Lipid Peroxidation; Liver; Male; Malondialdehyde; Melatonin; Mitochondria; Oxygen; Rats; Rats, Wistar; Reference Values; Structure-Activity Relationship; Tryptamines | 2002 |
Nimesulide and melatonin in mammary carcinogenesis prevention in female Sprague-Dawley rats.
Topics: Animals; Anticarcinogenic Agents; Carbohydrate Metabolism; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Female; Indomethacin; Isoenzymes; Lipid Metabolism; Mammary Neoplasms, Experimental; Melatonin; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfonamides | 2002 |
Effect of melatonin and beta-carotene on indomethacin induced gastric mucosal injury.
Topics: Animals; Antioxidants; beta Carotene; Gastric Mucosa; Indomethacin; Male; Melatonin; Peptic Ulcer; Rats; Rats, Wistar | 2002 |
Melatonin as treatment for idiopathic stabbing headache.
Topics: Adult; Drug Interactions; Female; Headache; Humans; Indomethacin; Melatonin; Middle Aged; Molecular Structure; Treatment Outcome; Warfarin | 2003 |
Studies on the anti-inflammatory effect of fluoxetine in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Carrageenan; Celecoxib; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Edema; Fluoxetine; Foot; Imipramine; Indomethacin; Inflammation; Lactones; Melatonin; Pyrazoles; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Sulfonamides; Sulfones; Time Factors; Trazodone | 2004 |
Melatonin produced metabolic changes in testis and did not prevent indomethacin-induced testicular lipid peroxidation in adult rat.
Topics: Animals; Indomethacin; Lipid Peroxidation; Male; Melatonin; Rats; Testis | 2003 |
Partial suppressive effect of melatonin on indomethacin-induced renal injury in rat.
Topics: Acid Phosphatase; Adenosine Triphosphatases; Animals; Antioxidants; Cyclooxygenase Inhibitors; Free Radicals; Glutathione; Indomethacin; Kidney; L-Lactate Dehydrogenase; Melatonin; Oxygen; Phosphates; Rats; Serum; Time Factors | 2004 |
Effect of melatonin on secreted and induced matrix metalloproteinase-9 and -2 activity during prevention of indomethacin-induced gastric ulcer.
Topics: Animals; Enzyme Induction; Indomethacin; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Melatonin; Oxidative Stress; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 2005 |
Importance of the pineal gland, endogenous prostaglandins and sensory nerves in the gastroprotective actions of central and peripheral melatonin against stress-induced damage.
Topics: Administration, Topical; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cerebral Ventricles; Cyclooxygenase 1; Cyclooxygenase 2; Gastrins; Immersion; Indomethacin; Melatonin; Neurons, Afferent; Pineal Gland; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Regional Blood Flow; Restraint, Physical; Stomach; Stomach Ulcer; Stress, Psychological; Tryptophan | 2005 |
Hydrogen peroxide-mediated downregulation of matrix metalloprotease-2 in indomethacin-induced acute gastric ulceration is blocked by melatonin and other antioxidants.
Topics: Animals; Antioxidants; Collagenases; Disease Models, Animal; DNA Primers; Enzyme Precursors; Gene Expression Regulation, Enzymologic; Hydrogen Peroxide; Indomethacin; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Melatonin; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Stomach Ulcer | 2006 |
Effect of sodium orthovanadate on the urinary bladder rings isolated from normal and hyperglycemic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hydrogen Peroxide; Hyperglycemia; In Vitro Techniques; Indomethacin; Male; Melatonin; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Streptozocin; Urinary Bladder; Vanadates | 2006 |
Protective effect of melatonin against multistress condition induced lipid peroxidation via measurement of gastric mucosal lesion and plasma malondialdehyde levels in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Bile Ducts; Gastric Mucosa; Indomethacin; Ligation; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Rats; Rats, Sprague-Dawley; Stress, Physiological | 2006 |
An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone indepe
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Catalysis; Dihydrotestosterone; Enzyme Inhibitors; Humans; Hydroxyprostaglandin Dehydrogenases; Indoles; Indomethacin; Melatonin; Neoplasms, Hormone-Dependent; Oxidation-Reduction; Phenanthrenes | 2008 |
Structural basis of the anti-inflammatory activity of melatonin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Foot; Indomethacin; Male; Melatonin; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Rats; Structure-Activity Relationship | 2007 |
Melatonin reduces indomethacin-induced gastric mucosal cell apoptosis by preventing mitochondrial oxidative stress and the activation of mitochondrial pathway of apoptosis.
Topics: Analysis of Variance; Animals; Antioxidants; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; bcl-X Protein; Caspase 3; Caspase 9; Cyclooxygenase Inhibitors; Gastric Mucosa; In Situ Nick-End Labeling; Indomethacin; Melatonin; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley | 2009 |
Characterization of mechanisms underlying the effects of esomeprazole on the impairment of gastric ulcer healing with addition of NSAID treatment.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Caspase 3; Dinoprostone; Disease Models, Animal; Esomeprazole; Famotidine; Indomethacin; Male; Malondialdehyde; Melatonin; NF-kappa B; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Stomach Ulcer; Treatment Outcome; Wound Healing | 2009 |
Induction of matrix metalloproteinase-9 and -3 in nonsteroidal anti-inflammatory drug-induced acute gastric ulcers in mice: regulation by melatonin.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Enzyme Induction; Gastric Mucosa; Indomethacin; Inflammation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Melatonin; Mice; Mice, Inbred BALB C; Oxidative Stress; Stomach Ulcer; Wound Healing | 2009 |
Melatonin promotes angiogenesis during protection and healing of indomethacin-induced gastric ulcer: role of matrix metaloproteinase-2.
Topics: Analysis of Variance; Animals; Gastric Mucosa; Histocytochemistry; Indomethacin; Male; Matrix Metalloproteinase 2; Melatonin; Mice; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Tissue Inhibitor of Metalloproteinase-2; Up-Regulation; Vascular Endothelial Growth Factor A; Wound Healing | 2010 |
Upregulation of collagenase-1 and -3 in indomethacin-induced gastric ulcer in diabetic rats: role of melatonin.
Topics: Analysis of Variance; Animals; Collagenases; Diabetes Mellitus, Experimental; Drug Interactions; Gelatinases; Histocytochemistry; Immunohistochemistry; Indomethacin; Male; Matrix Metalloproteinase 13; Melatonin; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Up-Regulation | 2011 |
Cluster headache in children and adolescents: ten years of follow-up in three pediatric cases.
Topics: Adolescent; Age of Onset; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Child; Cluster Headache; Down Syndrome; Drug Therapy, Combination; Dyspepsia; Female; Follow-Up Studies; Fructose; Humans; Incidence; Indomethacin; Lithium; Male; Melatonin; Prednisolone; Topiramate; Toxoplasmosis, Cerebral | 2011 |
[Gastroprotective activity of modified glutamyl-tryptophan dipeptide analogs and melatonin].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Cytoprotection; Dipeptides; Disease Models, Animal; Enteral Nutrition; Gastric Mucosa; Humans; Indomethacin; Male; Melatonin; Rats; Rats, Sprague-Dawley; Starvation; Stomach Ulcer; Stress, Physiological | 2012 |
Chronic gastric ulceration causes matrix metalloproteinases-9 and -3 augmentation: alleviation by melatonin.
Topics: Animals; Antioxidants; Blotting, Western; Chronic Disease; Extracellular Signal-Regulated MAP Kinases; Gastric Mucosa; Indomethacin; Interleukin-1beta; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Lipid Peroxidation; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Melatonin; Mice; Mice, Inbred BALB C; NF-kappa B; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Reverse Transcriptase Polymerase Chain Reaction; Stomach; Stomach Ulcer; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2012 |
[Neoplastic effect of indomethacin in N-methyl-N-nitrosourea induced mammary carcinogenesis in female rats].
Topics: Animals; Anticarcinogenic Agents; Chemoprevention; Female; Indomethacin; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley | 2012 |
Characteristics of post-traumatic headaches in children following mild traumatic brain injury and their response to treatment: a prospective cohort.
Topics: Adolescent; Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Brain Injuries; Central Nervous System Depressants; Child; Cohort Studies; Humans; Indomethacin; Male; Melatonin; Post-Traumatic Headache; Prospective Studies | 2013 |
Melatonin responsive hemicrania continua in which indomethacin was associated with contralateral headache.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System Depressants; Female; Headache; Humans; Indomethacin; Melatonin; Middle Aged; Migraine Disorders | 2014 |
A case of post-traumatic LASH syndrome responsive to indomethacin and melatonin (a man with a unique triad of indomethacin-responsive trigeminal autonomic cephalalgias).
Topics: Accidents, Traffic; Adult; Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System Depressants; Headache Disorders; Humans; Indomethacin; Male; Melatonin; Trigeminal Autonomic Cephalalgias | 2015 |
Does melatonin addition to indomethacin decrease post endoscopic retrograde cholangiopancreatography pancreatitis? A randomized double-blind controlled trial.
Topics: Adult; Aged; Amylases; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cholangiopancreatography, Endoscopic Retrograde; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Indomethacin; Lipase; Male; Melatonin; Middle Aged; Pancreatitis; Postoperative Complications; Severity of Illness Index | 2019 |
Melatonin rescues swim stress induced gastric ulceration by inhibiting matrix metalloproteinase-3 via down-regulation of inflammatory signaling cascade.
Topics: Animals; Down-Regulation; Indomethacin; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Melatonin; Mice; Stomach Ulcer | 2022 |