melatonin and cytochrome c-t

melatonin has been researched along with cytochrome c-t in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	17 (33.33)	29.6817
2010's	27 (52.94)	24.3611
2020's	7 (13.73)	2.80

Authors

Authors	Studies
Chen, KB; Chiu, TH; Lin, AM	1
Hoijman, E; Keller Sarmiento, MI; Pecci, A; Rocha Viegas, L; Rosenstein, RE	1
Jou, MJ; Jou, SB; Peng, TI; Reiter, RJ; Wen, ST; Wu, HY	1
Korik, E; Naumova, M; Semak, I; Slominski, A; Terekhovich, V; Wortsman, J	1
Caputi, S; Di Primio, R; Moroni, F; Pizzicannella, J; Recchioni, R; Trubiani, O	1
Akbulut, M; Baydas, G; Reiter, RJ; Tamer, S; Tuzcu, M	1
Carter, LB; Jevtovic-Todorovic, V; Reiter, RJ; Yon, JH	1
Han, YX; Wang, XM; Wu, JB; Zhang, SH	1
Ariznavarreta, C; Kireev, RA; Tresguerres, AF; Tresguerres, JA; Vara, E	1
Barrio, JP; García-Mediavilla, MV; González, P; González-Gallego, J; Mauriz, JL; Molpeceres, V	1
Ariznavarreta, C; Borras, C; Kireev, R; Tresguerres, AF; Tresguerres, JA; Vara, E	1
Cerella, C; Cristofanon, S; D'Alessio, M; De Nicola, M; Dicato, M; Diederich, M; Ghibelli, L; Paternoster, L; Radogna, F	1
Guo, L; Lu, HP; Si, HY; Sun, M; Xu, PP; Xu, YP; Yan, H	1
Arcangeletti, M; Betti, M; Canonico, B; Ferri, P; Galli, F; Luchetti, F; Papa, S	1
Day, AL; Figueroa, BE; Friedlander, RM; Kristal, BS; Sirianni, AC; Stavrovskaya, IG; Wang, X; Zhang, Y; Zhu, S	1
Moro, N; Paradies, G; Petrosillo, G; Ruggiero, FM	1
Colantuono, G; Di Venosa, N; Fiore, T; Moro, N; Paradies, G; Petrosillo, G; Ruggiero, FM; Tiravanti, E	1
Barriga, C; Bejarano, I; Espino, J; Pariente, JA; Redondo, PC; Reiter, RJ; Rodríguez, AB; Rosado, JA	1
Moro, N; Paradies, G; Paradies, V; Petrosillo, G; Ruggiero, FM	1
Fang, XH; Khiabani, KT; Stephenson, LL; Wang, WZ; Zamboni, WA; Zhang, X	1
Jou, MJ; Peng, TI	1
Agostinelli, E; Battaglia, V; Bragadin, M; Grancara, S; Maritati, M; Martinis, P; Rizzoli, V; Toninello, A; Zago, L	1
Liu, B; Liu, Y; Wang, Z; Wu, Z; Zhang, H; Zhang, L; Zhao, W	1
Chen, X; Liang, YL; Liu, XJ; Liu, XQ; Tao, L; Wang, H; Xu, DX; Zhang, C; Zhang, YF; Zhang, ZH	1
Chen, W; Duan, W; Jin, Z; Li, Y; Liang, Z; Wang, N; Yan, J; Yang, Y; Yi, D; Yi, W; Yu, S	1
Baranov, SV; Bennett, E; Browser, RP; Carlisle, DL; Cook, A; Cormier, K; Day, AL; Ferrante, RJ; Friedlander, RM; Jiang, J; Kim, J; Smith, K; Wang, X; Zhang, Y	1
Cabrera, J; Estévez, F; Loro, J; Perdomo, J; Quintana, J; Reiter, RJ	1
Govitrapong, P; Jumnongprakhon, P; Tocharus, C; Tocharus, J; Tungkum, W	1
Damiani, G; Favero, G; Paganelli, C; Reiter, RJ; Rezzani, R; Rodella, LF	1
Chen, G; Chen, J; Gu, C; Hu, Q; Li, J; Wang, L; Wu, C; Yan, F; Yan, W	1
Galano, A; Hardeland, R; Manchester, LC; Reiter, RJ; Tan, DX	1
Ding, K; Li, T; Wang, H; Wu, Y; Xu, J; Zhang, L	1
Deng, W; Fu, L; Huang, W; Lu, JJ; Qin, L; Shi, D; Tang, Z; Wang, J; Xiao, X; Xie, F; Yu, Z; Zhang, C	1
Akcakaya, H; Guven, C; Taskin, E	1
Aghsami, M; Gharghabi, M; Gholizadeh, S; Khorshidahmad, T; Mehdizadeh, H; Sanati, M; Sharif, R; Sharifzadeh, M; Taghizadeh, G; Vakilzadeh, G	1
Akatov, V; Azarashvili, T; Baburina, Y; Krestinina, O; Lemasters, JJ; Odinokova, I	1
Guo, XH; Li, YH; Zhai, YZ; Zhang, LC; Zhao, YS	1
Duan, W; Fan, C; Gong, B; Jin, Z; Li, B; Li, Z; Meng, D; Wang, H; Xu, Y; Xue, X; Yang, Y; Yu, L; Yu, S; Zhang, J; Zhang, M	1
Bonomini, F; D'Amato, L; Favero, G; Finati, E; Formenti, P; Iapichino, G; Mistraletti, G; Paroni, R; Reiter, RJ; Rezzani, R; Sabbatini, G; Taverna, M; Umbrello, M	1
Kong, L; Su, X; Sun, N; Wei, M; Zhu, J	1
Choudhury, A; Kar, S; Parvez, S; Sahu, U; Salman, M; Tabassum, H; Waseem, M	1
Baranov, SV; Baranova, OV; Carlisle, DL; Cecon, E; Di Benedetto, G; Ferrando, LM; Friedlander, RM; Gable, MJ; Guillaumet, G; He, Y; Heath, BE; Jean-Alphonse, FG; Jia, J; Jockers, R; Khattar, NK; Kim, J; Kretz, ES; Larkin, TM; Leronni, D; Lezon, TR; Li, J; Li, W; Mihalik, AC; Minnigh, MB; Poloyac, SM; Richardson, RM; Stolz, DB; Sullivan, M; Suofu, Y; Suzenet, F; Vilardaga, JP; Wang, J; Wang, X; Wehbi, VL; Witt-Enderby, PA; Yablonska, S	1
Akçay, NC; Aydin, V; Dernek, D; Dizakar, SÖA; Kartal, B; Ömeroğlu, S; Türkoğlu, İ	1
Cheang, T; Chen, L; Chen, S; Feng, J; Pei, Z; Su, F; Zheng, Y; Zhou, H	1
Kaushik, P; Parvez, S; Salman, M; Tabassum, H	1
Fang, Y; Jia, G; Xiang, H; Zhao, C; Zhong, R	1
Ajmal, S; Ali, T; Anees, M; Bakhtiar, A; Ishtiaq, A; Khan, U; Khan, W; Murtaza, I; Mushtaq, I; Saeed, J; Silas, E; Sultan, A; Wahedi, HM	1
Guo, Y; Kitazawa, H; Li, L; Liu, Z; Sun, Y; Wang, X; Yu, S; Zhang, L; Zhang, X	1
Ding, M; Meng, J; Zhang, Y; Zheng, B; Zhou, J; Zhu, Y	1
Kobylińska, A; Posmyk, MM	1
Cao, Y; Li, S; Wei, Z; Xue, R; Zhang, Z	1

Reviews

1 review(s) available for melatonin and cytochrome c-t

Article	Year
Oxidative stress caused by mitochondrial calcium overload. Annals of the New York Academy of Sciences, 2010, Volume: 1201 Topics: Animals; Calcium; Cardiolipins; Cyclosporine; Cytochromes c; Humans; Melatonin; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Signal Transduction	2010

Trials

1 trial(s) available for melatonin and cytochrome c-t

Article	Year
Melatonin Pharmacological Blood Levels Increase Total Antioxidant Capacity in Critically Ill Patients. International journal of molecular sciences, 2017, Apr-03, Volume: 18, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Circadian Rhythm; Critical Illness; Cytochromes c; Double-Blind Method; Drug Administration Schedule; Female; Humans; Intensive Care Units; Lymphocytes; Male; Melatonin; Microscopy, Confocal; Middle Aged; Nitric Oxide Synthase Type II; Oxidative Stress; Time Factors; Treatment Outcome; Young Adult	2017

Article

Year

Melatonin Pharmacological Blood Levels Increase Total Antioxidant Capacity in Critically Ill Patients.

International journal of molecular sciences, 2017, Apr-03, Volume: 18, Issue:4

Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Circadian Rhythm; Critical Illness; Cytochromes c; Double-Blind Method; Drug Administration Schedule; Female; Humans; Intensive Care Units; Lymphocytes; Male; Melatonin; Microscopy, Confocal; Middle Aged; Nitric Oxide Synthase Type II; Oxidative Stress; Time Factors; Treatment Outcome; Young Adult

2017

Other Studies

49 other study(ies) available for melatonin and cytochrome c-t

Article	Year
Oxidative injury to the locus coeruleus of rat brain: neuroprotection by melatonin. Journal of pineal research, 2003, Volume: 35, Issue:2 Topics: Animals; Antioxidants; Cytochromes c; Glial Cell Line-Derived Neurotrophic Factor; In Situ Nick-End Labeling; Iron; Lipid Peroxidation; Locus Coeruleus; Male; Melatonin; Nerve Growth Factors; Neurotoxins; Oxidative Stress; Rats; Rats, Sprague-Dawley	2003
Involvement of Bax protein in the prevention of glucocorticoid-induced thymocytes apoptosis by melatonin. Endocrinology, 2004, Volume: 145, Issue:1 Topics: Adjuvants, Immunologic; Animals; Apoptosis; bcl-2-Associated X Protein; Cytochromes c; Dexamethasone; Glucocorticoids; Male; Melatonin; Mice; Mice, Inbred Strains; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Glucocorticoid; RNA, Messenger; Thymus Gland	2004
Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes. Journal of pineal research, 2004, Volume: 37, Issue:1 Topics: Animals; Apoptosis; Astrocytes; Brain; Caspase 3; Caspases; Cytochromes c; Hydrogen Peroxide; Intracellular Membranes; Melatonin; Microscopy, Fluorescence, Multiphoton; Mitochondria; Oxidative Stress; Rats; Reactive Oxygen Species	2004
A novel metabolic pathway of melatonin: oxidation by cytochrome C. Biochemistry, 2005, Jul-05, Volume: 44, Issue:26 Topics: Animals; Cytochromes c; Hydrogen Peroxide; Male; Melatonin; Oxidation-Reduction; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet	2005
Melatonin provokes cell death in human B-lymphoma cells by mitochondrial-dependent apoptotic pathway activation. Journal of pineal research, 2005, Volume: 39, Issue:4 Topics: Annexin A5; Apoptosis; Blotting, Western; Burkitt Lymphoma; Caspase 3; Caspases; Cell Cycle; Cytochromes c; Down-Regulation; Enzyme Activation; Flow Cytometry; Humans; Melatonin; Membrane Potentials; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured	2005
Melatonin inhibits neural apoptosis induced by homocysteine in hippocampus of rats via inhibition of cytochrome c translocation and caspase-3 activation and by regulating pro- and anti-apoptotic protein levels. Neuroscience, 2005, Volume: 135, Issue:3 Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cytochromes c; Cytosol; DNA Fragmentation; Enzyme Activation; Gene Expression Regulation; Glutathione Peroxidase; Hippocampus; Homocysteine; Lipid Peroxidation; Male; Melatonin; Mitochondria; Neurons; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Translocation, Genetic	2005
Melatonin reduces the severity of anesthesia-induced apoptotic neurodegeneration in the developing rat brain. Neurobiology of disease, 2006, Volume: 21, Issue:3 Topics: Anesthetics, General; Animals; Apoptosis; bcl-X Protein; Blotting, Western; Brain; Caspase 3; Caspases; Cytochromes c; Dose-Response Relationship, Drug; Melatonin; Mitochondria; Nerve Degeneration; Neuroprotective Agents; Rats; Rats, Sprague-Dawley	2006
Inhibition of mitochondria responsible for the anti-apoptotic effects of melatonin during ischemia-reperfusion. Journal of Zhejiang University. Science. B, 2006, Volume: 7, Issue:2 Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cerebellum; Cytochromes c; Cytoplasm; DNA Fragmentation; Glucose; Immunoblotting; Melatonin; Membrane Potentials; Mitochondria; Neurons; Nitric Oxide Synthase Type I; Oxygen; Rats; Rats, Sprague-Dawley; Reperfusion; Reperfusion Injury; Time Factors	2006
Effect of chronic treatments with GH, melatonin, estrogens, and phytoestrogens on oxidative stress parameters in liver from aged female rats. Biogerontology, 2007, Volume: 8, Issue:5 Topics: Aging; Animals; Antioxidants; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; Estrogens; Female; Glutathione Transferase; Growth Hormone; Liver; Melatonin; Mitochondria, Liver; Nitric Oxide; Ovariectomy; Oxidative Stress; Phytoestrogens; Rats; Rats, Wistar	2007
Melatonin is able to reduce the apoptotic liver changes induced by aging via inhibition of the intrinsic pathway of apoptosis. The journals of gerontology. Series A, Biological sciences and medical sciences, 2007, Volume: 62, Issue:7 Topics: Aging; Animals; Apoptosis; Caspase 3; Caspase 8; Cytochromes c; Glutathione; Liver; Male; Melatonin; Oxidation-Reduction; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Thiobarbiturates	2007
Molecular mechanisms involved in the hormonal prevention of aging in the rat. The Journal of steroid biochemistry and molecular biology, 2008, Volume: 108, Issue:3-5 Topics: Aging; Animals; Central Nervous System; Cytochromes c; Cytosol; Estradiol; Estrogens; Female; Growth Hormone; Isoflavones; Liver; Male; Melatonin; Mitochondria, Liver; Nitric Oxide; Ovariectomy; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Skin Physiological Phenomena	2008
Melatonin antagonizes the intrinsic pathway of apoptosis via mitochondrial targeting of Bcl-2. Journal of pineal research, 2008, Volume: 44, Issue:3 Topics: Apoptosis; bcl-2-Associated X Protein; Cytochromes c; Humans; Melatonin; Microscopy, Fluorescence; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Puromycin; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; RNA, Small Interfering; Tryptamines; U937 Cells	2008
[Effects of melatonin on nerve cell apoptosis and expression of Bcl-2 & cytochrome C genes in rat cerebrum with deltamethrin induction]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2008, Volume: 26, Issue:4 Topics: Animals; Apoptosis; Cells, Cultured; Cytochromes c; Female; Hippocampus; Melatonin; Neurons; Nitriles; Proto-Oncogene Proteins c-bcl-2; Pyrethrins; Rats; Rats, Wistar	2008
ERK MAPK activation mediates the antiapoptotic signaling of melatonin in UVB-stressed U937 cells. Free radical biology & medicine, 2009, Feb-01, Volume: 46, Issue:3 Topics: Apoptosis; Cytochromes c; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; Melatonin; Mitochondria; Monocytes; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Pyridines; Radiation Tolerance; Signal Transduction; U937 Cells; Ultraviolet Rays	2009
Methazolamide and melatonin inhibit mitochondrial cytochrome C release and are neuroprotective in experimental models of ischemic injury. Stroke, 2009, Volume: 40, Issue:5 Topics: Animals; Antioxidants; Blotting, Western; Brain Ischemia; Carbonic Anhydrase Inhibitors; Caspase 1; Caspase 3; Cell Death; Cytochromes c; Enzyme Activation; In Situ Nick-End Labeling; Interleukin-1beta; L-Lactate Dehydrogenase; Melatonin; Membrane Potentials; Methazolamide; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Membranes; Neurodegenerative Diseases; Neurons; Neuroprotective Agents	2009
Melatonin inhibits cardiolipin peroxidation in mitochondria and prevents the mitochondrial permeability transition and cytochrome c release. Free radical biology & medicine, 2009, Oct-01, Volume: 47, Issue:7 Topics: Animals; Calcium; Cardiolipins; Cytochromes c; Lipid Peroxidation; Melatonin; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Oxidation-Reduction; Rats	2009
Melatonin protects against heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening. American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:4 Topics: Animals; Antioxidants; Calcium; Cardiolipins; Cardiovascular Agents; Cyclosporine; Cytochromes c; Heart Rate; In Vitro Techniques; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Melatonin; Membrane Potential, Mitochondrial; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NAD; Necrosis; Perfusion; Rats; Rats, Wistar; Recovery of Function; Time Factors; Ventricular Function, Left; Ventricular Pressure	2009
Melatonin reduces apoptosis induced by calcium signaling in human leukocytes: Evidence for the involvement of mitochondria and Bax activation. The Journal of membrane biology, 2010, Volume: 233, Issue:1-3 Topics: Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Calcium; Caspase 3; Caspase 9; Cell Survival; Cells, Cultured; Cytochromes c; Enzyme Inhibitors; Humans; Immunoprecipitation; Leukocytes; Melatonin; Mitochondria; Thapsigargin	2010
Increased susceptibility to Ca(2+)-induced permeability transition and to cytochrome c release in rat heart mitochondria with aging: effect of melatonin. Journal of pineal research, 2010, Volume: 48, Issue:4 Topics: Aging; Analysis of Variance; Animals; Calcium; Cardiolipins; Cytochromes c; Male; Melatonin; Membrane Potential, Mitochondrial; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Rats; Rats, Wistar	2010
Melatonin attenuates I/R-induced mitochondrial dysfunction in skeletal muscle. The Journal of surgical research, 2011, Volume: 171, Issue:1 Topics: Animals; Antioxidants; Benzimidazoles; Carbocyanines; Cytochromes c; Fluorescent Dyes; Male; Melatonin; Membrane Potential, Mitochondrial; Mitochondria, Muscle; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxides	2011
Interactions of melatonin with mammalian mitochondria. Reducer of energy capacity and amplifier of permeability transition. Amino acids, 2012, Volume: 42, Issue:5 Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Calcium; Cyclosporine; Cytochromes c; Energy Metabolism; Hydrogen Peroxide; Melatonin; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Membranes; Oxidative Stress; Permeability; Rats	2012
Exogenous melatonin modulates apoptosis in the mouse brain induced by high-LET carbon ion irradiation. Journal of pineal research, 2012, Volume: 52, Issue:1 Topics: Analysis of Variance; Animals; Antioxidants; Apoptosis; Blotting, Western; Brain; Brain Chemistry; Caspase 3; Cytochromes c; In Situ Nick-End Labeling; Male; Melatonin; Membrane Potential, Mitochondrial; Mice; Oxidative Stress; Radiation, Ionizing	2012
Melatonin protects against apoptosis-inducing factor (AIF)-dependent cell death during acetaminophen-induced acute liver failure. PloS one, 2012, Volume: 7, Issue:12 Topics: Acetaminophen; Animals; Antioxidants; Apoptosis Inducing Factor; Cell Death; Cytochrome P-450 CYP2E1; Cytochromes c; Enzyme Activation; Glutathione; GTPase-Activating Proteins; Hepatocytes; JNK Mitogen-Activated Protein Kinases; Liver Failure, Acute; Male; Melatonin; Mice; Phosphorylation; Protein Transport	2012
New role of JAK2/STAT3 signaling in endothelial cell oxidative stress injury and protective effect of melatonin. PloS one, 2013, Volume: 8, Issue:3 Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Adhesion; Cell Movement; Cell Shape; Cell Survival; Cytochromes c; Glutathione Peroxidase; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Janus Kinase 2; L-Lactate Dehydrogenase; Malondialdehyde; Melatonin; Oxidative Stress; Phosphorylation; Protective Agents; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; Superoxide Dismutase; Tyrphostins	2013
Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobiology of disease, 2013, Volume: 55 Topics: Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Antioxidants; Caspase 3; Cell Death; Cytochromes c; Disease Models, Animal; Disease Progression; Enzyme-Linked Immunosorbent Assay; Melatonin; Mice; Mice, Transgenic; Receptor, Melatonin, MT1; Signal Transduction; Superoxide Dismutase	2013
Melatonin induces apoptosis through a caspase-dependent but reactive oxygen species-independent mechanism in human leukemia Molt-3 cells. Journal of pineal research, 2013, Volume: 55, Issue:2 Topics: Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 9; Cell Line, Tumor; Cytochromes c; Drug Evaluation, Preclinical; Humans; Leukemia; Melatonin; Reactive Oxygen Species	2013
Protective effect of melatonin on methamphetamine-induced apoptosis in glioma cell line. Neurotoxicity research, 2014, Volume: 25, Issue:3 Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Nucleus; Cell Nucleus Shape; Cytochromes c; Melatonin; Methamphetamine; Mitochondria; Neuroprotective Agents; Rats; Time Factors	2014
Attenuation of ultraviolet A-induced alterations in NIH3T3 dermal fibroblasts by melatonin. The British journal of dermatology, 2014, Volume: 170, Issue:2 Topics: Animals; Antioxidants; Caspase 3; Collagen Type I; Collagen Type II; Cytochromes c; Fibroblasts; Fibronectins; Fluorescent Antibody Technique; Heme Oxygenase-1; Melatonin; Mice; NIH 3T3 Cells; Skin; Transforming Growth Factor beta1; Ultraviolet Rays	2014
Melatonin-enhanced autophagy protects against neural apoptosis via a mitochondrial pathway in early brain injury following a subarachnoid hemorrhage. Journal of pineal research, 2014, Volume: 56, Issue:1 Topics: Analysis of Variance; Animals; Apoptosis; Autophagy; bcl-2-Associated X Protein; Brain Injuries; Cytochromes c; In Situ Nick-End Labeling; Male; Melatonin; Mitochondria; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage	2014
Cyclic-3-hydroxymelatonin (C3HOM), a potent antioxidant, scavenges free radicals and suppresses oxidative reactions. Current medicinal chemistry, 2014, Volume: 21, Issue:13 Topics: Antioxidants; Cytochromes c; Free Radical Scavengers; Horseradish Peroxidase; Hydrogen-Ion Concentration; Kinetics; Melatonin; Oxidation-Reduction	2014
Melatonin protects the brain from apoptosis by enhancement of autophagy after traumatic brain injury in mice. Neurochemistry international, 2015, Volume: 91 Topics: Adenine; Animals; Apoptosis; Autophagy; bcl-2-Associated X Protein; Body Water; Brain Chemistry; Brain Injuries; Cerebral Cortex; Cytochromes c; Male; Melatonin; Mice; Mitochondria; Neuroprotective Agents; Signal Transduction	2015
Melatonin inhibits AP-2β/hTERT, NF-κB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells. Oncotarget, 2016, Jan-19, Volume: 7, Issue:3 Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Berberine; Caspase 9; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytochromes c; DNA-Binding Proteins; Extracellular Signal-Regulated MAP Kinases; Lung Neoplasms; Male; Melatonin; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Telomerase; Transcription Factor AP-2; Xenograft Model Antitumor Assays	2016
Melatonin Prevents Mitochondrial Damage Induced by Doxorubicin in Mouse Fibroblasts Through Ampk-Ppar Gamma-Dependent Mechanisms. Medical science monitor : international medical journal of experimental and clinical research, 2016, Feb-10, Volume: 22 Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Apoptosis; Caspase 3; Cell Survival; Cytochromes c; Doxorubicin; Drug Interactions; Fibroblasts; Melatonin; Membrane Potential, Mitochondrial; Mice; Mitochondria; NIH 3T3 Cells; Oxidative Stress; PPAR gamma	2016
Melatonin reverses H-89 induced spatial memory deficit: Involvement of oxidative stress and mitochondrial function. Behavioural brain research, 2017, 01-01, Volume: 316 Topics: Animals; Antioxidants; Cytochromes c; Disease Models, Animal; Escape Reaction; Hippocampus; Hypnotics and Sedatives; Isoquinolines; Lipid Peroxidation; Male; Melatonin; Membrane Potential, Mitochondrial; Memory Disorders; Mitochondria; Protein Kinase Inhibitors; Rats; Rats, Wistar; Reaction Time; Reactive Oxygen Species; Sulfonamides; Xylazine	2017
2',3'-Cyclic nucleotide 3'-phosphodiesterase as a messenger of protection of the mitochondrial function during melatonin treatment in aging. Biochimica et biophysica acta. Biomembranes, 2017, Volume: 1859, Issue:1 Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; Aging; Animals; Antioxidants; Calcium; Cyclic AMP; Cytochromes c; Male; Melatonin; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Rats	2017
Anti‑aging effects of melatonin on the myocardial mitochondria of rats and associated mechanisms. Molecular medicine reports, 2017, Volume: 15, Issue:1 Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aging; Animals; Antioxidants; bcl-2-Associated X Protein; Cytochromes c; Galactose; Male; Melatonin; Mitochondria, Heart; Myocardium; Proto-Oncogene Proteins c-bcl-2; Rats, Sprague-Dawley	2017
Melatonin ameliorates myocardial ischemia/reperfusion injury in type 1 diabetic rats by preserving mitochondrial function: role of AMPK-PGC-1α-SIRT3 signaling. Scientific reports, 2017, 01-25, Volume: 7 Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Cardiotonic Agents; Cytochromes c; Cytosol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucose; Glucose Tolerance Test; Male; Melatonin; Mice; Mitochondria; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; Sirtuin 3; Streptozocin; Superoxide Dismutase; Transcription Factors	2017
[Role of melatonin in calcium overload-induced heart injury]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2017, Jun-28, Volume: 42, Issue:6 Topics: Animals; Calcium; Caspase 3; Coloring Agents; Cytochromes c; Heart; Heart Injuries; L-Lactate Dehydrogenase; Male; Melatonin; Myocardial Infarction; Myocardium; Perfusion; Rats; Rats, Sprague-Dawley; Tetrazolium Salts	2017
Melatonin pre-treatment mitigates SHSY-5Y cells against oxaliplatin induced mitochondrial stress and apoptotic cell death. PloS one, 2017, Volume: 12, Issue:7 Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Melatonin; Membrane Potential, Mitochondrial; Mitochondria; Neuroprotective Agents; Organoplatinum Compounds; Oxaliplatin; Oxidative Stress; Reactive Oxygen Species; Superoxides	2017
Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release. Proceedings of the National Academy of Sciences of the United States of America, 2017, 09-19, Volume: 114, Issue:38 Topics: Animals; Brain Injuries; Brain Ischemia; Cytochromes c; Male; Melatonin; Mice; Mitochondria; Receptor, Melatonin, MT1; Signal Transduction	2017
Possible effects of melatonin against rat uterus exposure to bisphenol A during neonatal period. Environmental science and pollution research international, 2017, Volume: 24, Issue:34 Topics: Animals; Animals, Newborn; Apoptosis; Benzhydryl Compounds; Cytochromes c; Environmental Pollutants; Female; Melatonin; Phenols; Proto-Oncogene Proteins c-bcl-2; Rats; Uterus	2017
Melatonin inhibits rotenone-induced SH-SY5Y cell death via the downregulation of Dynamin-Related Protein 1 expression. European journal of pharmacology, 2018, Jan-15, Volume: 819 Topics: Cell Death; Cell Line, Tumor; Cytochromes c; Cytoprotection; Dose-Response Relationship, Drug; Down-Regulation; Dynamins; GTP Phosphohydrolases; Humans; Melatonin; Microtubule-Associated Proteins; Mitochondria; Mitochondrial Proteins; Neurons; Protein Transport; Rotenone	2018
Melatonin Provides Neuroprotection Following Traumatic Brain Injury-Promoted Mitochondrial Perturbation in Wistar Rat. Cellular and molecular neurobiology, 2021, Volume: 41, Issue:4 Topics: Animals; bcl-2-Associated X Protein; Behavior, Animal; Brain Edema; Brain Injuries, Traumatic; Caspase 3; Cytochromes c; Dynamins; Male; Melatonin; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Dynamics; Mitochondrial Proteins; Mitochondrial Proton-Translocating ATPases; Models, Biological; Neurons; Neuroprotection; Oxidative Phosphorylation; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats, Wistar	2021
Melatonin improves cryopreservation of ram sperm by inhibiting mitochondrial permeability transition pore opening. Reproduction in domestic animals = Zuchthygiene, 2020, Volume: 55, Issue:9 Topics: Animals; Cell Membrane; Cryopreservation; Cytochromes c; Fertilization in Vitro; Freezing; Male; Melatonin; Membrane Potential, Mitochondrial; Mitochondrial Permeability Transition Pore; Receptors, Melatonin; Semen Preservation; Sheep, Domestic; Spermatozoa	2020
Pistacia integerrima alleviated Bisphenol A induced toxicity through Ubc13/p53 signalling. Molecular biology reports, 2020, Volume: 47, Issue:9 Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Benzhydryl Compounds; Blood Glucose; Cytochromes c; Dynamins; Female; Hypodermoclysis; Kidney; Lipid Metabolism; Liver; Male; Melatonin; Oxidative Stress; Phenols; Pistacia; Plant Extracts; Plant Tumors; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53; Ubiquitin-Conjugating Enzymes; Up-Regulation	2020
Melatonin retards senescence via regulation of the electron leakage of postharvest white mushroom (Agaricus bisporus). Food chemistry, 2021, Mar-15, Volume: 340 Topics: Adenosine Triphosphate; Agaricus; Cytochromes c; Electron Transport Complex III; Electrons; Energy Metabolism; Food Quality; Food Storage; Fungal Proteins; Gene Expression Regulation, Fungal; Melatonin	2021
Melatonin enhances SIRT1 to ameliorate mitochondrial membrane damage by activating PDK1/Akt in granulosa cells of PCOS. Journal of ovarian research, 2021, Nov-11, Volume: 14, Issue:1 Topics: 3-Phosphoinositide-Dependent Protein Kinases; Adult; Animals; bcl-2-Associated X Protein; Benzimidazoles; Carbocyanines; Cytochromes c; Cytoplasm; Female; Gene Knockdown Techniques; Granulosa Cells; Humans; Melatonin; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Polycystic Ovary Syndrome; Proto-Oncogene Proteins c-akt; Sirtuin 1	2021
Melatonin Protects Tobacco Suspension Cells against Pb-Induced Mitochondrial Dysfunction. International journal of molecular sciences, 2021, Dec-13, Volume: 22, Issue:24 Topics: Antioxidants; Apoptosis; Calcium; Caspases; Cell Proliferation; Cell Survival; Cytochromes c; Lead; Melatonin; Membrane Potential, Mitochondrial; Mitochondria; Nicotiana; Oxidative Stress; Reactive Oxygen Species	2021
Melatonin attenuates di-(2-ethylhexyl) phthalate-induced apoptosis of human granulosa cells by inhibiting mitochondrial fission. Reproductive toxicology (Elmsford, N.Y.), 2022, Volume: 113 Topics: AMP-Activated Protein Kinases; Apoptosis; Cytochromes c; Diethylhexyl Phthalate; Dynamins; Female; Granulosa Cells; Humans; Melatonin; Mitochondrial Dynamics; Phthalic Acids; Plasticizers; Reactive Oxygen Species	2022