melatonin has been researched along with colforsin in 133 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (9.02) | 18.7374 |
| 1990's | 62 (46.62) | 18.2507 |
| 2000's | 46 (34.59) | 29.6817 |
| 2010's | 9 (6.77) | 24.3611 |
| 2020's | 4 (3.01) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Chik, CL; Ho, AK | 1 |
| Zatz, M | 1 |
| Barrett, P; Davidson, G; Hastings, MH; Lawson, W; Morgan, PJ; Thompson, M | 1 |
| Guerrero, JM; Menendez-Pelaez, A; Reiter, RJ; Santana, C | 1 |
| Kasper, G; Marquez, CR; Zatz, M | 1 |
| Hashemi, F; Niles, LP | 1 |
| Deng, MH; Lopez G-Coviella, I; Lynch, HJ; Wurtman, RJ | 1 |
| Vanĕcek, J | 2 |
| Niles, LP; Pickering, DS; Ye, M; Ying, SW | 1 |
| Janavs, JL; Pierce, ME; Takahashi, JS | 2 |
| Buzzell, GR; Menendez-Pelaez, A; Nonaka, KO; Reiter, RJ | 1 |
| Hashemi, FS; Niles, LP | 1 |
| Besharse, JC; Iuvone, PM | 1 |
| Guerrero, JM; Reiter, RJ; Santana, C; Troiani, ME | 1 |
| Barker, D; Harrington, J; Pierce, ME; Takahashi, JS | 1 |
| Pratt, BL; Takahashi, JS | 1 |
| Nikaido, SS; Takahashi, JS | 1 |
| Yuwiler, A | 1 |
| Guerrero, JM; Reiter, RJ; Santana, C | 1 |
| Mullen, DA; Zatz, M | 2 |
| Brun-Marmillon, J; Claustrat, B; Collin, JP; Falcón, J | 1 |
| Gonzalez-Brito, A; Guerrero, JM; Menendez-Pelaez, A; Reiter, RJ; Santana, C | 1 |
| Rollag, MD; Sekura, RD; White, BH | 1 |
| Bubis, M; Zisapel, N | 1 |
| Gan, J; Iuvone, PM | 1 |
| Ebisawa, T; Karne, S; Lerner, MR; Reppert, SM | 1 |
| Barrett, P; Davidson, G; Hazlerigg, D; Lawson, W; MacLean, A; Milligan, G; Morgan, PJ | 1 |
| Hastings, MH; McNulty, S; Morgan, PJ; Schurov, IL | 1 |
| Gonzalez-Brito, A; Hastings, MH; Hazlerigg, DG; Lawson, W; Morgan, PJ | 1 |
| Nash, MS; Osborne, NN | 2 |
| Florez, JC; Janavs, JL; Pierce, ME; Takahashi, JS | 1 |
| Barrett, P; Hastings, MH; McNulty, S; Morgan, PJ; Ross, AW | 1 |
| Chidlow, G; Osborne, NN | 1 |
| Caignard, DH; Delagrange, P; Depreux, P; Guardiola, B; Howell, HE; Lesieur, D; Mansour, HA; Morgan, P; Pfeiffer, B; Renard, P | 1 |
| Hastings, MH; Hazlerigg, DG; Morgan, PJ | 1 |
| Capsoni, S; De Oliveira, AM; Saavedra, JM; Viswanathan, M | 1 |
| Davidson, G; Hastings, MH; Lawson, W; McNulty, S; Morgan, PJ; Thompson, M | 1 |
| Barrett, P; Davidson, G; Hazlerigg, D; Lawson, W; Morgan, PJ | 1 |
| Collin, JP; Falcón, J; Gern, WA; Greenhouse, SS; Lowery, CA; Thibault, C | 1 |
| Crocker, C; Niles, LP; Ying, SW | 1 |
| Klein, DC; Vanecek, J | 1 |
| Hastings, MH; Hazlerigg, DG; Morgan, PJ; Thompson, M | 1 |
| Fauteck, JD; Fischer, B; Madeja, M; Musshoff, U; Speckmann, EJ; Wittkowski, W | 1 |
| Baker, J; Ermak, G; Gaudet, SJ; Grande, M; Guisti, LW; Rosano, TG; Slominski, A | 1 |
| Dubocovich, ML; Witt-Enderby, PA | 1 |
| Barrett, P; Morgan, PJ; Ross, AW | 1 |
| Lerchl, A; Niedziela, M; Nieschlag, E | 1 |
| Barrett, P; Davidson, G; MacLean, A; Morgan, PJ | 1 |
| Hastings, MH; McNulty, S; Morgan, PJ; Ross, AW; Shiu, KY | 1 |
| Caillol, M; Martinet, L; Messager, S; Rossano, B | 1 |
| Barrett, P; Mercer, JG; Morgan, PJ; Ross, AW | 1 |
| Andersson, RG; Moartensson, LG | 1 |
| Barrett, P; Canning, SJ; Conway, S; Delagrange, P; Drew, JE; Guardiola-Lemaitre, B; Jockers, R; Morgan, PJ; Strosberg, AD | 1 |
| Balsamini, C; Di Giacomo, B; Diamantini, G; Fraschini, F; Lucini, V; Mor, M; Nonno, R; Pannacci, M; Plazzi, PV; Rivara, S; Spadoni, G; Stankov, BM; Tarzia, G | 1 |
| Di Giacomo, B; Diamantini, G; Esposti, D; Fraschini, F; Lucini, V; Nonno, R; Pannacci, M; Spadoni, G; Stankov, BM; Tarzia, G | 1 |
| Hastings, MH; McNulty, S; McNulty, TJ; Morgan, PJ; Schurov, IL | 1 |
| Abete, P; Bianco, S; Cacciatore, F; Calabrese, C; Ferrara, N; Napoli, C; Rengo, F | 1 |
| Duffield, GE; Ebling, FJ; Hastings, MH; Kidd, A; Maywood, ES; Schurov, I | 1 |
| Barraud, S; Bégay, V; Falcón, J; Thibault, C | 1 |
| Lamosová, D; Macková, M; Zeman, M | 1 |
| Dubocovich, ML; Masana, MI; Witt-Enderby, PA | 1 |
| Adam, C; Barrett, P; Graham, ES; Messager, S; Morgan, PJ; Ross, AW | 1 |
| Li, L; Pang, SF; Shiu, SY; Wong, JT; Wong, YH; Xu, JN | 1 |
| Barrett, P; Coon, SL; Fleming, JV; Klein, DC; Morgan, PJ | 1 |
| Allen, CN; Marino, JL; Nelson, CS | 1 |
| Cahill, GM; Hasegawa, M | 1 |
| Flanders, S; Lew, MJ | 1 |
| Calvo, JR; García-Pergañeda, A; Guerrero, JM; Paz Romero, M; Pozo, D; Rafii-El-Idrissi, M | 1 |
| Blask, DE; Dauchy, RT; Holowachuk, EW; Kopff, HS; Ruhoff, MS; Sauer, LA | 1 |
| Graham, ES; Hazlerigg, DG; Morgan, PJ | 1 |
| Pelisek, V; Slanar, O; Vanecek, J | 1 |
| Alonso-Bedate, M; Alonso-Gómez, AL; Delgado, MJ; Valenciano, AI | 1 |
| Beresford, I; Browning, C; Fraser, N; Giles, H | 1 |
| Jones, MP; Melan, MA; Witt-Enderby, PA | 1 |
| Beckmann, A; Fauteck, JD; Musshoff, U; Peschke, D; Peschke, E; Schmidt, F | 1 |
| Gastel, JA; Heath, JR; Klein, DC; Zatz, M | 1 |
| Korf, HW; Kroeber, S; Maronde, E; Meissl, H | 1 |
| Pelísek, V; Vanecek, J | 1 |
| Barrett, P; Choi, WS; Morgan, P; Morris, M | 1 |
| Karlsson, AM; Lerner, MR; Lundström, I; Svensson, SP; Unett, D | 1 |
| Abreu, P; Alonso, R; Hernández-Díaz, FJ; López-Coviella, I; Prieto, L; Sánchez, JJ; Tabares, L | 1 |
| Coon, SL; Klein, DC; Korf, HW; Namboodiri, MA; Rollag, M; Weller, JL | 1 |
| Blask, DE; Dauchy, RT; Sauer, LA | 1 |
| Abreu, P; Moujir, F; Reiter, RJ; Sanchez, J; Santana, C | 1 |
| Pang, SF; Poon, AM; Zhao, H | 1 |
| Blackhurst, G; Connell, JM; Fraser, R; McElroy, PK; Swan, RL | 1 |
| MacKenzie, RS; Melan, MA; Passey, DK; Witt-Enderby, PA | 1 |
| Markowska, M; Mrozkowiak, A; Skwarlo-Sonta, K | 1 |
| Becq, F; Falcón, J; Gaildrat, P | 1 |
| Giusti, M; Valenti, S | 1 |
| Chankiewitz, E; Csernus, VJ; Mühlbauer, E; Musshoff, U; Peschke, D; Peschke, E | 1 |
| Carpinelli, AR; Cipolla-Neto, J; Curi, R; de Oliveira Carvalho, CR; Haber, EP; Picinato, MC | 1 |
| Arilla-Ferreiro, E; Boyano-Adánez, Mdel C; Izquierdo-Claros, RM | 1 |
| Graham, ES; Hazlerigg, DG; Morgan, PJ; Webster, CA | 1 |
| Chen, J; Deskus, JA; Epperson, JR; Hodges, DB; Iben, L; Li, WS; Luo, G; Mahle, CD; Mattson, RJ; Molstad, D; Ortiz, A; Ryan, E; Sun, LQ; Takaki, K; Xu, C; Yeleswaram, K | 1 |
| Andrade, LN; Castrucci, AM; Floeter-Winter, LM; Kadekaro, AL; Rollag, MD; Vieira, W; Virador, V | 1 |
| Angeloni, D; Azeddine, B; Forget, S; Fraschini, F; Grimard, G; Labelle, H; Moreau, A; Poitras, B; Rivard, CH; Wang, DS | 1 |
| Markowska, M; Mrozkowiak, A; Pawlak, J; Skwarło-Sońta, K | 1 |
| Jarzynka, MJ; Krawitt, BJ; Melan, MA; Witt-Enderby, PA | 1 |
| Alonso-Vale, MI; Andreotti, S; Anhê, GF; das Neves Borges-Silva, C; Lima, FB; Neto, JC; Peres, SB | 1 |
| De Loof, A; Huybrechts, J; Schoofs, L | 1 |
| Ebadi, M; Govitrapong, P; Santanavanich, C | 1 |
| Barrett, P; Morgan, PJ; Morris, A; Schuster, C; Williams, LM | 1 |
| Dubocovich, ML; Masana, MI; Soares, JM | 1 |
| Ha, DC; Han, S; Kim, KT; Kim, TD | 1 |
| Csernus, VJ | 1 |
| Aust, S; Brucker, B; Graf, J; Klimpfinger, M; Thalhammer, T | 1 |
| Brydon, L; Ignatius, PF; Jarzynka, MJ; Jockers, R; Melan, MA; Passey, DK; Radio, NM; Rasenick, MM; Witt-Enderby, PA | 1 |
| Azeddine, B; Letellier, K; Moldovan, F; Moreau, A; Wang, da S | 1 |
| Mühlbauer, E; Peschke, E; Stumpf, I | 1 |
| Alarma-Estrany, P; Crooke, A; Mediero, A; Peláez, T; Pintor, J | 1 |
| Genade, S; Genis, A; Huisamen, B; Lochner, A; Ytrehus, K | 1 |
| Chen, Q; Dong, C; Frasch, T; Hill, SM; Lai, L; Mao, L; Rowan, B; Yuan, L | 1 |
| Sampaio, Lde F | 1 |
| Bazwinsky-Wutschke, I; Mühlbauer, E; Peschke, E; Wolgast, S | 1 |
| Boczek-Leszczyk, E; Juszczak, M | 1 |
| Guerra, M; Pedreros, M; Ratto, M | 1 |
| Albrecht, E; Bazwinsky-Wutschke, I; Mühlbauer, E; Peschke, E; Wolgast, S | 1 |
| Bojunga, J; Fischer, C; Iigo, M; Korf, HW; Yasuo, S | 1 |
| Juszczak, M; Roszczyk, M | 1 |
| Hirai, K; Nishiyama, K | 1 |
| Bojanowska, E; Juszczak, M; Krzyminska, A; Roszczyk, M | 1 |
| Honma, KI; Honma, S; Yamada, Y; Yamanaka, Y | 1 |
| Adornetto, A; Bagetta, G; Corasaniti, MT; Morrone, LA; Nucci, C; Rombolà, L; Russo, R | 1 |
| Asma, A; Marc-André, S | 1 |
| Ramsay, S; Zagorodnyuk, V | 1 |
| Aguiar, FLN; Azevedo, VAN; Barrozo, LG; Batista, ALPS; Costa, FC; Donato, MAM; Lopes, EPF; Nascimento, DR; Paulino, LRFM; Peixoto, CA; Rodrigues, APR; Silva, BR; Silva, JRV | 1 |
2 review(s) available for melatonin and colforsin
| Article | Year |
|---|---|
Non-photic signalling in the suprachiasmatic nucleus.
Topics: Afferent Pathways; Age Factors; Animals; Animals, Newborn; Arousal; Calcium; Circadian Rhythm; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Handling, Psychological; Injections, Subcutaneous; Melatonin; Mesocricetus; Mice; Mice, Inbred C57BL; Neurotransmitter Agents; Phodopus; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-fos; Raphe Nuclei; Rodentia; Signal Transduction; Sodium Chloride; Species Specificity; Suprachiasmatic Nucleus; Thalamus | 1997 |
Natural Products: Evidence for Neuroprotection to Be Exploited in Glaucoma.
Topics: Amides; Biological Products; Colforsin; Curcumin; Cytidine Diphosphate Choline; Dietary Supplements; Ethanolamines; Fatty Acids, Unsaturated; Flavonoids; Ginkgo biloba; Glaucoma; Humans; Melatonin; Neuroprotective Agents; Palmitic Acids; Phytotherapy; Plant Extracts; Resveratrol; Taurine; Tea; Ubiquinone; Vitamins | 2020 |
131 other study(ies) available for melatonin and colforsin
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Inhibitors of Na(+)-H+ exchange block stimulus-provoked pineal melatonin synthesis.
Topics: Amiloride; Animals; Arylamine N-Acetyltransferase; Bucladesine; Carrier Proteins; Colforsin; Cyclic AMP; Hydrogen-Ion Concentration; Male; Melatonin; Pineal Gland; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Sympathomimetics | 1992 |
Does the circadian pacemaker act through cyclic AMP to drive the melatonin rhythm in chick pineal cells?
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Biological Clocks; Chickens; Circadian Rhythm; Colforsin; Cyclic AMP; Melatonin; Pineal Gland | 1992 |
Intracellular signalling in the ovine pars tuberalis: an investigation using aluminium fluoride and melatonin.
Topics: Aluminum; Aluminum Compounds; Animals; Binding Sites; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Fluorides; Inositol Phosphates; Melatonin; Pituitary Gland, Anterior; Sheep; Signal Transduction | 1991 |
Treatment with forskolin for 8 hours during the day increases melatonin synthesis in the Syrian hamster pineal gland in organ culture: the long lag period is required for RNA synthesis.
Topics: Animals; Colforsin; Cricetinae; Male; Melatonin; Mesocricetus; Organ Culture Techniques; Pineal Gland; RNA | 1990 |
Vasoactive intestinal peptide stimulates chick pineal melatonin production and interacts with other stimulatory and inhibitory agents but does not show alpha 1-adrenergic potentiation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Chickens; Colforsin; Drug Interactions; Isoproterenol; Kinetics; Light; Melatonin; Nitrendipine; Norepinephrine; Phenylephrine; Pineal Gland; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1990 |
Picomolar-affinity binding and inhibition of adenylate cyclase activity by melatonin in Syrian hamster hypothalamus.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Animals; Binding Sites; Colforsin; Cricetinae; Hypothalamus; Iodine Radioisotopes; Male; Melatonin; Mesocricetus; Radioligand Assay; Receptors, Melatonin; Receptors, Neurotransmitter | 1990 |
Melatonin and its precursors in Y79 human retinoblastoma cells: effect of sodium butyrate.
Topics: 5-Hydroxytryptophan; Analysis of Variance; Butyrates; Butyric Acid; Cell Line; Colforsin; Dopamine; Eye Neoplasms; Humans; Kinetics; Levodopa; Melatonin; Retinoblastoma; Serotonin; Spiperone | 1991 |
Melatonin inhibitory effect on luteinizing hormone release is potentiated after long pretreatment with the indole.
Topics: Animals; Animals, Newborn; Colforsin; Cyclic AMP; Female; Gonadotropin-Releasing Hormone; Indoles; Luteinizing Hormone; Melatonin; Pituitary Gland; Rats; Rats, Inbred Strains | 1991 |
Pertussis toxin blocks melatonin-induced inhibition of forskolin-stimulated adenylate cyclase activity in the chick brain.
Topics: Adenylate Cyclase Toxin; Animals; Brain; Cell Membrane; Chickens; Colforsin; Kinetics; Melatonin; Pertussis Toxin; Retina; Synaptosomes; Virulence Factors, Bordetella | 1991 |
N-acetyltransferase and protein synthesis modulate melatonin production by Y79 human retinoblastoma cells.
Topics: Acetylserotonin O-Methyltransferase; Anisomycin; Arylamine N-Acetyltransferase; Cell Line; Colforsin; Cycloheximide; Eye Neoplasms; Humans; Kinetics; Melatonin; Neoplasm Proteins; Retinoblastoma | 1991 |
In vivo administration of isoproterenol or forskolin during the light phase induces increases in the melatonin content of the Syrian hamster pineal gland without a rise in N-acetyltransferase activity.
Topics: Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Circadian Rhythm; Colforsin; Cricetinae; Isoproterenol; Lighting; Melatonin; Mesocricetus; Pineal Gland; Receptors, Adrenergic, beta | 1990 |
Pharmacological inhibition of forskolin-stimulated adenylate cyclase activity in rat brain by melatonin, its analogs, and diazepam.
Topics: Adenylyl Cyclases; Animals; Benzodiazepinones; Brain; Brain Mapping; Cell Membrane; Colforsin; Corpus Striatum; Diazepam; Dose-Response Relationship, Drug; Enzyme Activation; Flumazenil; In Vitro Techniques; Male; Melatonin; Rats; Rats, Inbred Strains | 1990 |
Cyclic AMP stimulates serotonin N-acetyltransferase activity in Xenopus retina in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Acetyltransferases; Adenosine; Animals; Arylamine N-Acetyltransferase; Bucladesine; Calcium; Circadian Rhythm; Colforsin; Cyclic AMP; Darkness; Fishes; Guinea Pigs; In Vitro Techniques; Light; Melatonin; Retina; Tyrosine 3-Monooxygenase; Xenopus laevis | 1986 |
The in vitro activation of cyclic AMP production by either forskolin or isoproterenol in the Syrian hamster pineal during the day is not accompanied by an increase in melatonin production.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Circadian Rhythm; Colforsin; Cricetinae; Cyclic AMP; Isoproterenol; Kinetics; Male; Melatonin; Mesocricetus; Organ Culture Techniques; Pineal Gland | 1988 |
Cyclic AMP-dependent melatonin production in Y79 human retinoblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 5-Hydroxytryptophan; 8-Bromo Cyclic Adenosine Monophosphate; Colforsin; Cyclic AMP; Humans; Melatonin; Middle Aged; Retinoblastoma; Tumor Cells, Cultured | 1989 |
Vasoactive intestinal polypeptide and alpha 2-adrenoceptor agonists regulate adenosine 3',5'-monophosphate accumulation and melatonin release in chick pineal cell cultures.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Agonists; Amino Acid Sequence; Animals; Brimonidine Tartrate; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Kinetics; Melatonin; Molecular Sequence Data; Pineal Gland; Quinoxalines; Radioimmunoassay; Sequence Homology, Nucleic Acid; Structure-Activity Relationship; Vasoactive Intestinal Peptide | 1989 |
Twenty-four hour oscillation of cAMP in chick pineal cells: role of cAMP in the acute and circadian regulation of melatonin production.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Chickens; Circadian Rhythm; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Male; Melatonin; Pineal Gland | 1989 |
Effects of steroids on serotonin-N-acetyltransferase activity of pineals in organ culture.
Topics: Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Bucladesine; Cholera Toxin; Colforsin; Corticosterone; Dose-Response Relationship, Drug; Hydrocortisone; Indoles; Isoproterenol; Male; Melatonin; Organ Culture Techniques; Pineal Gland; Rats; Rats, Inbred F344; Steroids; Tryptophan | 1989 |
Effects of either forskolin, the 1,9-dideoxy derivative of forskolin, or 8-bromocyclic AMP on cyclic AMP and melatonin production in the Syrian hamster pineal gland in organ culture.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cricetinae; Cyclic AMP; Male; Melatonin; Mesocricetus; Organ Culture Techniques; Pineal Gland; Radioimmunoassay; Rats; Rats, Inbred Strains | 1989 |
Photoendocrine transduction in cultured chick pineal cells. II. Effects of forskolin, 8-bromocyclic AMP, and 8-bromocyclic GMP on the melatonin rhythm.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Chickens; Circadian Rhythm; Colforsin; Cyclic GMP; Lighting; Melatonin; Pineal Gland | 1988 |
Melatonin production in organ cultured chicken pineal: modulation by adenosine and its analogs.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Animals; Chickens; Colforsin; Deoxyadenosines; Dipyridamole; Melatonin; Organ Culture Techniques; Phenylisopropyladenosine; Pineal Gland; Thioinosine | 1988 |
Norepinephrine, acting via adenylate cyclase, inhibits melatonin output but does not phase-shift the pacemaker in cultured chick pineal cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cells, Cultured; Chickens; Circadian Rhythm; Colforsin; Lighting; Melatonin; Norepinephrine; Photic Stimulation; Pineal Gland | 1988 |
Forskolin, an activator of adenylate cyclase activity, promotes large increases in N-acetyl transferase activity and melatonin production in the Syrian hamster pineal gland only during the late dark period.
Topics: Acetyltransferases; Adenylyl Cyclases; Animals; Arylamine N-Acetyltransferase; Circadian Rhythm; Colforsin; Cricetinae; Darkness; Enzyme Activation; Enzyme Induction; Male; Melatonin; Mesocricetus; Pineal Gland | 1988 |
Pertussis toxin blocks melatonin-induced pigment aggregation in Xenopus dermal melanophores.
Topics: Adenylate Cyclase Toxin; Animals; Cell Aggregation; Cells, Cultured; Colforsin; Melanocytes; Melanophores; Melatonin; Pertussis Toxin; Virulence Factors, Bordetella; Xenopus laevis | 1987 |
Modulation by melatonin of protein secretion from melanoma cells: is cAMP involved?
Topics: Animals; Bucladesine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoquinolines; Melanoma, Experimental; Melatonin; Mice; Protein Biosynthesis; Proteins; Sulfonamides; Tumor Cells, Cultured | 1995 |
Melatonin receptor-mediated inhibition of cyclic AMP accumulation in chick retinal cell cultures.
Topics: 1-Methyl-3-isobutylxanthine; 5-Methoxytryptamine; Animals; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Iodine Radioisotopes; Melatonin; Neurons; Pertussis Toxin; Photoreceptor Cells; Potassium; Receptors, Cell Surface; Receptors, Melatonin; Retina; Second Messenger Systems; Structure-Activity Relationship; Tryptamines; Virulence Factors, Bordetella | 1994 |
Expression cloning of a high-affinity melatonin receptor from Xenopus dermal melanophores.
Topics: Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Cells, Cultured; Chlorocebus aethiops; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; DNA; DNA, Complementary; Gene Expression; Kidney; Kinetics; Melanophores; Melatonin; Molecular Sequence Data; Poly A; Protein Structure, Secondary; Receptors, Cell Surface; Receptors, Melatonin; RNA; RNA, Messenger; Skin; Transcription, Genetic; Transfection; Xenopus laevis | 1994 |
Melatonin receptors couple through a cholera toxin-sensitive mechanism to inhibit cyclic AMP in the ovine pituitary.
Topics: Adenosine Diphosphate Ribose; Animals; Base Sequence; Blotting, Northern; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; GTP-Binding Proteins; Iodine Radioisotopes; Melatonin; Molecular Sequence Data; NAD; Pertussis Toxin; Pituitary Gland; Receptors, Cell Surface; Receptors, Melatonin; RNA, Messenger; Sheep; Virulence Factors, Bordetella | 1995 |
The inhibitory action of melatonin in the ovine pars tuberalis is not dependent on changes in plasma membrane potential.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Female; Male; Melatonin; Membrane Potentials; Pituitary Gland; Potassium; Saponins; Sheep; Stimulation, Chemical; Valinomycin | 1995 |
Prolonged exposure to melatonin leads to time-dependent sensitization of adenylate cyclase and down-regulates melatonin receptors in pars tuberalis cells from ovine pituitary.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Aluminum; Aluminum Compounds; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Down-Regulation; Fluorides; Iodine Radioisotopes; Kinetics; Melatonin; Pituitary Gland, Anterior; Receptors, Melatonin; Receptors, Neurotransmitter; Sheep | 1993 |
Melatonin inhibits increase of intracellular calcium and cyclic AMP in neonatal rat pituitary via independent pathways.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Calcium; Colforsin; Cyclic AMP; Gonadotropin-Releasing Hormone; GTP-Binding Proteins; Intracellular Fluid; Melatonin; Pituitary Gland, Anterior; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Melatonin; Second Messenger Systems | 1995 |
Pertussis toxin-sensitive melatonin receptors negatively coupled to adenylate cyclase associated with cultured human and rat retinal pigment epithelial cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adult; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Melatonin; Pertussis Toxin; Pigment Epithelium of Eye; Rats; Receptors, Cell Surface; Receptors, Melatonin; Virulence Factors, Bordetella | 1995 |
Forskolin and camptothecin induce a 30 kDa protein associated with melatonin production in Y79 human retinoblastoma cells.
Topics: Camptothecin; Colforsin; Humans; Immunoblotting; Melatonin; Molecular Weight; Neoplasm Proteins; Retinoblastoma; Time Factors; Tumor Cells, Cultured | 1995 |
Melatonin regulates the phosphorylation of CREB in ovine pars tuberalis.
Topics: Animals; Base Sequence; Cell Nucleus; Cells, Cultured; Colforsin; Consensus Sequence; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Melatonin; Molecular Sequence Data; Phosphorylation; Pituitary Gland, Anterior; Protein Kinase C; Sheep; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
The presence of functional melatonin receptors in the iris-ciliary processes of the rabbit eye.
Topics: Animals; Autoradiography; Ciliary Body; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Iris; Melatonin; Rabbits; Receptors, Cell Surface; Receptors, Melatonin; Serotonin | 1994 |
Synthesis and structure-activity relationships of novel naphthalenic and bioisosteric related amidic derivatives as melatonin receptor ligands.
Topics: Acetamides; Animals; Cell Membrane; Colforsin; Cyclic AMP; Iodine Radioisotopes; Ligands; Melatonin; Molecular Structure; Pituitary Gland, Anterior; Receptors, Cell Surface; Receptors, Melatonin; Sheep; Structure-Activity Relationship | 1994 |
The recovery of ovine pars tuberalis cells from melatonin-induced sensitization is a slow, protein synthesis-dependent phenomenon.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cycloheximide; Drug Synergism; Electrophoresis, Polyacrylamide Gel; Female; Kinetics; Male; Melatonin; Nerve Tissue Proteins; Pituitary Gland, Anterior; Protein Kinases; Sheep | 1994 |
Characterization of melatonin receptors and signal transduction system in rat arteries forming the circle of Willis.
Topics: Animals; Arteries; Circle of Willis; Colforsin; Cyclic AMP; Male; Melatonin; Nucleotides; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Melatonin; Signal Transduction | 1994 |
RNA synthesis inhibitors increase melatonin production in Y79 human retinoblastoma cells.
Topics: Amidohydrolases; Anisomycin; Arylamine N-Acetyltransferase; Calcium; Camptothecin; Colforsin; Cyclic AMP; Dactinomycin; Dopamine; Egtazic Acid; Eye Neoplasms; Humans; Melatonin; Nerve Tissue Proteins; Protein Synthesis Inhibitors; Retinoblastoma; Topoisomerase I Inhibitors; Transcription, Genetic; Tumor Cells, Cultured | 1994 |
Phospholipases and melatonin signal transduction in the ovine pars tuberalis.
Topics: Adenylyl Cyclases; Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Choline; Colforsin; Cyclic AMP; Female; Lysophospholipids; Male; Melatonin; Membrane Lipids; Phosphatidic Acids; Phospholipases; Phospholipids; Pituitary Gland, Anterior; Second Messenger Systems; Sheep; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
p72, a marker protein for melatonin action in ovine pars tuberalis cells: its regulation by protein kinase A and protein kinase C and differential secretion relative to prolactin.
Topics: Animals; Autoradiography; Biomarkers; Calcium; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Female; Gonadotropin-Releasing Hormone; Kinetics; Male; Melatonin; Methionine; Microtubules; Nerve Tissue Proteins; Pituitary Gland, Anterior; Prolactin; Protein Kinase C; Receptors, LHRH; Sheep | 1994 |
Regulation of melatonin production by pineal photoreceptor cells: role of cyclic nucleotides in the trout (Oncorhynchus mykiss).
Topics: Animals; Arylamine N-Acetyltransferase; Colforsin; Cyclic AMP; Melatonin; Nucleotides, Cyclic; Photoreceptor Cells; Pineal Gland; Temperature; Theophylline; Trout | 1993 |
Human malignant melanoma cells express high-affinity receptors for melatonin: antiproliferative effects of melatonin and 6-chloromelatonin.
Topics: Adenylyl Cyclase Inhibitors; Cell Division; Cell Membrane; Colforsin; Cyclic AMP; DNA, Neoplasm; Humans; Indoles; Iodine Radioisotopes; Kinetics; Melanoma; Melatonin; Nucleotides; Receptors, Melatonin; Receptors, Neurotransmitter; Tumor Cells, Cultured | 1993 |
Agonist-induced effects on cyclic AMP metabolism are affected in pigment epithelial cells of the Royal College of Surgeons rat.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Alprostadil; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Fibroblast Growth Factor 2; Imidazoles; Isoproterenol; Kinetics; Melatonin; Pigment Epithelium of Eye; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta-2; Receptors, Purinergic P1; Serotonin | 1995 |
Mechanism of melatonin signal transduction in the neonatal rat pituitary.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Calcimycin; Calcium; Colforsin; Cyclic AMP; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Melatonin; Nifedipine; Organ Culture Techniques; Pituitary Gland, Anterior; Rats; Receptors, Cell Surface; Receptors, Melatonin; Signal Transduction | 1995 |
Regulation of mitogen-activated protein kinase in the pars tuberalis of the ovine pituitary: interactions between melatonin, insulin-like growth factor-1, and forskolin.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cytosol; Enzyme Activation; Humans; Immunohistochemistry; Insulin-Like Growth Factor I; Melatonin; Mitogen-Activated Protein Kinase 1; Myelin Basic Protein; Phosphorylation; Pituitary Gland, Anterior; Protein-Tyrosine Kinases; Receptors, Somatomedin; Recombinant Proteins; Sheep; Tissue Distribution; Tissue Extracts | 1996 |
Expression and functional characterization of a melatonin-sensitive receptor in Xenopus oocytes.
Topics: Animals; Anthracenes; Autoradiography; Binding Sites; Brain; Caffeine; Colforsin; Cyclic AMP; Female; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Melatonin; Membrane Potentials; Microinjections; Oocytes; Patch-Clamp Techniques; Pertussis Toxin; Rats; Receptors, Cell Surface; Receptors, Melatonin; RNA, Messenger; Virulence Factors, Bordetella | 1996 |
Metabolism of serotonin to N-acetylserotonin, melatonin, and 5-methoxytryptamine in hamster skin culture.
Topics: 5-Methoxytryptamine; Animals; Chromatography, High Pressure Liquid; Colforsin; Cricetinae; Gas Chromatography-Mass Spectrometry; Male; Melatonin; Mesocricetus; Organ Culture Techniques; Serotonin; Skin; Tritium | 1996 |
Characterization and regulation of the human ML1A melatonin receptor stably expressed in Chinese hamster ovary cells.
Topics: Animals; Binding, Competitive; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Humans; Kinetics; Melatonin; Receptors, Cell Surface; Receptors, Melatonin; Recombinant Proteins; Transfection; Tryptamines | 1996 |
Melatonin regulated gene expression in pars tuberalis cells of the ovine pituitary investigated by differential display.
Topics: Animals; Colforsin; Cycloheximide; DNA-Binding Proteins; Gene Expression; Melatonin; Pituitary Gland; Polymerase Chain Reaction; Proto-Oncogene Proteins c-fos; Sheep; Transcription Factors | 1996 |
Direct effects of the pineal hormone melatonin on testosterone synthesis of Leydig cells in Djungarian hamsters (Phodopus sungorus) in vitro.
Topics: Animals; Colforsin; Cricetinae; Dose-Response Relationship, Drug; In Vitro Techniques; Leydig Cells; Luteinizing Hormone; Male; Melatonin; Testosterone | 1995 |
Regulation of the Mel 1a melatonin receptor mRNA and protein levels in the ovine pars tuberalis: evidence for a cyclic adenosine 3',5'-monophosphate-independent Mel 1a receptor coupling and an autoregulatory mechanism of expression.
Topics: Animals; Cells, Cultured; Colforsin; Culture Media, Serum-Free; Cyclic AMP; Dactinomycin; Melatonin; Pituitary Gland, Anterior; Protein Synthesis Inhibitors; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; RNA, Messenger; Sheep; Time Factors; Transcription, Genetic; Up-Regulation | 1996 |
Phosphorylation of CREB in ovine pars tuberalis is regulated both by cyclic AMP-dependent and cyclic AMP-independent mechanisms.
Topics: Adenosine; Animals; Blood Physiological Phenomena; Blotting, Western; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dinoprostone; Female; Immunohistochemistry; Male; Melatonin; Phosphorylation; Pituitary Gland, Anterior; Serine; Sheep | 1996 |
Effect of melatonin on the release of gonadotropin-releasing hormone and cyclic AMP from the rat hypothalamus: an in vitro study.
Topics: Animals; Colforsin; Cyclic AMP; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; In Vitro Techniques; Male; Melatonin; Preoptic Area; Rats; Rats, Wistar; Reproducibility of Results | 1996 |
Melatonin suppresses the induction of AP-1 transcription factor components in the pars tuberalis of the pituitary.
Topics: Animals; Base Sequence; Blotting, Northern; Cells, Cultured; Colforsin; Female; Gene Expression; Genes, jun; In Situ Hybridization; Insulin-Like Growth Factor I; Male; Melatonin; Oligonucleotide Probes; Pituitary Gland, Anterior; Proto-Oncogene Proteins c-jun; RNA, Messenger; Sheep; Transcription Factor AP-1; Transcription, Genetic | 1996 |
Denervation of pigment cells lead to a receptor that is ultrasensitive to melatonin and noradrenaline.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Colforsin; Denervation; Fishes; Melanins; Melanophores; Melatonin; Norepinephrine; Peripheral Nervous System; Prazosin; Yohimbine | 1997 |
Identification of Mel1a melatonin receptors in the human embryonic kidney cell line HEK293: evidence of G protein-coupled melatonin receptors which do not mediate the inhibition of stimulated cyclic AMP levels.
Topics: Binding, Competitive; Cell Line; Colforsin; Cyclic AMP; Genomic Library; GTP-Binding Proteins; Humans; Kidney; Melatonin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; RNA, Messenger; Sequence Analysis, DNA; Serotonin; Signal Transduction; Tryptamines | 1997 |
Conformationally restrained melatonin analogues: synthesis, binding affinity for the melatonin receptor, evaluation of the biological activity, and molecular modeling study.
Topics: Animals; Binding, Competitive; Chickens; Colforsin; Cyclic AMP; Drug Design; Guanosine 5'-O-(3-Thiotriphosphate); Melatonin; Models, Molecular; Quail; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Superior Colliculi | 1997 |
1-(2-Alkanamidoethyl)-6-methoxyindole derivatives: a new class of potent indole melatonin analogues.
Topics: Animals; Binding Sites; Binding, Competitive; Chickens; Colforsin; Cyclic AMP; Drug Design; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Melatonin; Models, Chemical; Quail; Superior Colliculi | 1997 |
Melatonin-sensitive, serum-stimulated signalling in ovine pars tuberalis.
Topics: Animals; Blood; Cells, Cultured; Colforsin; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Down-Regulation; Enzyme Inhibitors; Female; Fluorescent Dyes; Fura-2; Genes, Immediate-Early; Immunoenzyme Techniques; Indoles; Male; Melatonin; Phosphorylation; Pituitary Gland, Anterior; Protein Kinase C; Proto-Oncogene Proteins c-fos; Sheep; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors | 1997 |
Effects of melatonin in isolated rat papillary muscle.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Isoproterenol; Male; Melatonin; Myocardial Contraction; Papillary Muscles; Rats; Rats, Inbred WKY; Stimulation, Chemical | 1997 |
Inhibitors of messenger RNA and protein synthesis affect differently serotonin arylalkylamine N-acetyltransferase activity in clock-controlled and non clock-controlled fish pineal.
Topics: Acetylserotonin O-Methyltransferase; Animals; Arylamine N-Acetyltransferase; Biological Clocks; Colforsin; Enzyme Activation; Esocidae; Female; Gene Expression Regulation, Enzymologic; Male; Melatonin; Oncorhynchus mykiss; Pineal Gland; RNA, Messenger; Serotonin | 1998 |
Regulation of rhythmic melatonin production in pineal cells of chick embryo by cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Chick Embryo; Colforsin; Cyclic AMP; Melatonin; Phosphodiesterase Inhibitors; Pineal Gland | 1998 |
Physiological exposure to melatonin supersensitizes the cyclic adenosine 3',5'-monophosphate-dependent signal transduction cascade in Chinese hamster ovary cells expressing the human mt1 melatonin receptor.
Topics: Animals; Catalysis; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; GTP-Binding Proteins; Humans; Melatonin; Pertussis Toxin; Phosphorylation; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Ribose; Signal Transduction; Time Factors; Virulence Factors, Bordetella | 1998 |
oPer1 is an early response gene under photoperiodic regulation in the ovine pars tuberalis.
Topics: Animals; Circadian Rhythm; Colforsin; Gene Expression; Gene Expression Regulation; Light; Melatonin; Nuclear Proteins; Photoperiod; Pituitary Gland; RNA, Messenger; Seasons; Sheep | 1998 |
Molecular and cellular analyses of melatonin receptor-mediated cAMP signaling in rat corpus epididymis.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dihydrotestosterone; DNA Primers; Epididymis; Epithelial Cells; GTP-Binding Proteins; In Situ Hybridization; Isoproterenol; Male; Melatonin; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 1998 |
Ovine arylalkylamine N-acetyltransferase in the pineal and pituitary glands: differences in function and regulation.
Topics: Animals; Arylamine N-Acetyltransferase; Colforsin; Cyclic AMP; Cyclic AMP Response Element Modulator; DNA-Binding Proteins; Female; Gene Expression Regulation; In Vitro Techniques; Male; Melatonin; Pineal Gland; Pituitary Gland; Repressor Proteins; RNA, Messenger | 1999 |
Melatonin receptor potentiation of cyclic AMP and the cystic fibrosis transmembrane conductance regulator ion channel.
Topics: Adenylate Cyclase Toxin; Animals; Chloride Channels; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Female; Melatonin; Oocytes; Pertussis Toxin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Receptors, Serotonin; Transfection; Virulence Factors, Bordetella; Xenopus laevis | 1999 |
Modulation of rhythmic melatonin synthesis in Xenopus retinal photoreceptors by cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Circadian Rhythm; Colforsin; Culture Techniques; Cyclic AMP; Enzyme Inhibitors; Male; Melatonin; Photoreceptor Cells, Vertebrate; Retina; Stimulation, Chemical; Thionucleotides; Xenopus laevis | 1999 |
Mechanisms of melatonin-induced vasoconstriction in the rat tail artery: a paradigm of weak vasoconstriction.
Topics: Acetamides; Animals; Anticonvulsants; Arteries; Calcium Channel Blockers; Charybdotoxin; Colforsin; Dose-Response Relationship, Drug; Hypnotics and Sedatives; In Vitro Techniques; Indoles; Male; Melatonin; Nifedipine; Nitroprusside; Potassium Channels; Rats; Rats, Sprague-Dawley; Tail; Tryptamines; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins | 1999 |
Characterization of membrane melatonin receptor in mouse peritoneal macrophages: inhibition of adenylyl cyclase by a pertussis toxin-sensitive G protein.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Blotting, Western; Colforsin; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gi-Go; Iodine Radioisotopes; Kinetics; Macrophages, Peritoneal; Melatonin; Mice; Neuroimmunomodulation; Pertussis Toxin; Radioligand Assay; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Serotonin; Signal Transduction; Tryptamines; Virulence Factors, Bordetella | 1999 |
Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biological Transport; Cell Division; Circadian Rhythm; Colforsin; Linoleic Acid; Linoleic Acids; Liver Neoplasms, Experimental; Male; Melatonin; Models, Biological; Naphthalenes; Perfusion; Pertussis Toxin; Rats; Rats, Inbred BUF; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Signal Transduction; Virulence Factors, Bordetella | 1999 |
Evidence for regulation of basic fibroblast growth factor gene expression by photoperiod and melatonin in the ovine pars tuberalis.
Topics: Animals; Cell Line; Cells, Cultured; Colforsin; Fibroblast Growth Factor 2; Gene Expression Regulation; Male; Melatonin; Photoperiod; Pituitary Gland, Anterior; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seasons; Sheep; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1999 |
Melatonin inhibits pituitary adenylyl cyclase-activating polypeptide-induced increase of cyclic AMP accumulation and [Ca2+]i in cultured cells of neonatal rat pituitary.
Topics: Animals; Animals, Newborn; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Female; Gonadotropin-Releasing Hormone; Melatonin; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland, Anterior; Rats; Rats, Wistar | 2000 |
Melatonin synthesis in the greenfrog retina in culture: I. Modulation by the light/dark cycle, forskolin and inhibitors of protein synthesis.
Topics: Animals; Antioxidants; Arylamine N-Acetyltransferase; Colforsin; Culture Media; Dactinomycin; Light; Melatonin; Organ Culture Techniques; Photoperiod; Protein Synthesis Inhibitors; Radioimmunoassay; Ranidae; Retina; Time Factors | 2000 |
Pharmacological characterization of human recombinant melatonin mt(1) and MT(2) receptors.
Topics: Animals; Binding, Competitive; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Humans; Isotope Labeling; Kinetics; Melatonin; Pertussis Toxin; Radioligand Assay; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Recombinant Proteins; Virulence Factors, Bordetella | 2000 |
Melatonin decreases cell proliferation and transformation in a melatonin receptor-dependent manner.
Topics: 3T3 Cells; Animals; Binding Sites; Cell Count; Cell Division; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; DNA; Humans; Melatonin; Mice; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Signal Transduction; Transfection; Tumor Stem Cell Assay | 2000 |
Evidence for a melatonin receptor within pancreatic islets of neonate rats: functional, autoradiographic, and molecular investigations.
Topics: Animals; Animals, Newborn; Autoradiography; Colforsin; DNA Primers; Dose-Response Relationship, Drug; Female; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Insulin; Insulin Secretion; Islets of Langerhans; Male; Melatonin; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tryptamines | 2000 |
Chick pineal melatonin synthesis: light and cyclic AMP control abundance of serotonin N-acetyltransferase protein.
Topics: Animals; Arylamine N-Acetyltransferase; Cells, Cultured; Chick Embryo; Circadian Rhythm; Colforsin; Cyclic AMP; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Activation; Leupeptins; Lighting; Melatonin; Multienzyme Complexes; Norepinephrine; Photoreceptor Cells, Vertebrate; Pineal Gland; Proteasome Endopeptidase Complex; Signal Transduction; Sympathomimetics | 2000 |
Analyses of signal transduction cascades reveal an essential role of calcium ions for regulation of melatonin biosynthesis in the light-sensitive pineal organ of the rainbow trout (Oncorhynchus mykiss).
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arylamine N-Acetyltransferase; Calcium; Calcium Signaling; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cysteine Endopeptidases; Female; Gene Expression; Immunohistochemistry; Male; Melatonin; Multienzyme Complexes; Oncorhynchus mykiss; Organ Culture Techniques; Phosphodiesterase Inhibitors; Phosphorylation; Photic Stimulation; Pineal Gland; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Signal Transduction; Transcription, Genetic | 2000 |
Different effects of melatonin pretreatment on cAMP and LH responses of the neonatal rat pituitary cells.
Topics: Animals; Animals, Newborn; Cells, Cultured; Colforsin; Female; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Melatonin; Pituitary Gland, Anterior; Rats; Rats, Wistar | 2000 |
A role for tyrosine phosphorylation in the regulation and sensitization of adenylate cyclase by melatonin.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Benzoquinones; Cells, Cultured; Colforsin; Cyclic AMP; Drug Synergism; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Isoenzymes; Lactams, Macrocyclic; Melatonin; Models, Biological; Phosphorylation; Phosphotyrosine; Pituitary Gland; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Rifabutin; RNA, Messenger; Sheep; Signal Transduction; Virulence Factors, Bordetella | 2000 |
Melatonin-induced organelle movement in melanophores is coupled to tyrosine phosphorylation of a high molecular weight protein.
Topics: Adenylate Cyclase Toxin; Animals; Blotting, Western; Cell Aggregation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Genistein; GTP-Binding Proteins; Kinetics; Melanophores; Melatonin; Pertussis Toxin; Phosphoprotein Phosphatases; Phosphorylation; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Serine; Signal Transduction; Threonine; Time Factors; Tyrosine; Virulence Factors, Bordetella; Xenopus | 2000 |
Estrogen modulates alpha(1)/beta-adrenoceptor- induced signaling and melatonin production in female rat pinealocytes.
Topics: Action Potentials; Animals; Arylamine N-Acetyltransferase; Calcium; Cholera Toxin; Colforsin; Cyclic AMP; Estradiol; Female; Hydrogen-Ion Concentration; Hydrolysis; Melatonin; Ovariectomy; Phosphatidylinositols; Pineal Gland; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Estradiol; Signal Transduction | 2001 |
cAmp regulation of arylalkylamine N-acetyltransferase (AANAT, EC 2.3.1.87): a new cell line (1E7) provides evidence of intracellular AANAT activation.
Topics: Animals; Arylalkylamine N-Acetyltransferase; Arylamine N-Acetyltransferase; Cell Extracts; Cell Line; Colforsin; COS Cells; Cyclic AMP; Cytoplasm; Darkness; Enzyme Activation; Escherichia coli; Humans; Kinetics; Melatonin; Pineal Gland; Rats; Rats, Sprague-Dawley; Tryptamines | 2001 |
Melatonin inhibits fatty acid transport in inguinal fat pads of hepatoma 7288CTC-bearing and normal Buffalo rats via receptor-mediated signal transduction.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipose Tissue; Animals; Biological Transport; Circadian Rhythm; Colforsin; Linoleic Acid; Liver Neoplasms, Experimental; Male; Melatonin; Naphthalenes; Neoplasm Transplantation; Pertussis Toxin; Rats; Rats, Inbred BUF; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Signal Transduction; Specific Pathogen-Free Organisms; Time Factors; Virulence Factors, Bordetella | 2001 |
Role of extracellular calcium on the regulation of melatonin synthesis in the Syrian hamster pineal gland.
Topics: Animals; Arylamine N-Acetyltransferase; Calcium; Colforsin; Cricetinae; Cyclic AMP; Male; Melatonin; Mesocricetus; Organ Culture Techniques; Pineal Gland | 2001 |
mt(1) Receptor-mediated antiproliferative effects of melatonin on the rat uterine antimesometrial stromal cells.
Topics: Adenylate Cyclase Toxin; Animals; Autoradiography; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Endometrium; Female; In Situ Hybridization; Melatonin; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Stromal Cells; Virulence Factors, Bordetella | 2002 |
Seasonal variation in glucocorticoid receptor binding characteristics in human mononuclear leucocytes.
Topics: Adenylyl Cyclase Inhibitors; Adult; Analysis of Variance; Cells, Cultured; Colforsin; Dexamethasone; Enzyme Inhibitors; Female; Humans; Hydrocortisone; Leukocytes, Mononuclear; Male; Melatonin; Protein Binding; Receptors, Glucocorticoid; Seasons | 2001 |
Dual coupling of MT(1) and MT(2) melatonin receptors to cyclic AMP and phosphoinositide signal transduction cascades and their regulation following melatonin exposure.
Topics: Analysis of Variance; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Drug Interactions; Humans; Hydrolysis; Melatonin; Phosphatidylinositols; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Signal Transduction; Tetrahydronaphthalenes; Transfection | 2002 |
Influence of melatonin on chicken lymphocytes in vitro: involvement of membrane receptors.
Topics: Animals; Antioxidants; Cell Division; Cell Membrane; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Lymphocytes; Male; Melatonin; Phytohemagglutinins; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Signal Transduction; Spleen; Tryptamines | 2002 |
First cloning and functional characterization of a melatonin receptor in fish brain: a novel one?
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Blotting, Northern; Brain; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cystic Fibrosis Transmembrane Conductance Regulator; Melatonin; Molecular Sequence Data; Phylogeny; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Superior Colliculi; Tetrahydronaphthalenes | 2002 |
Melatonin participates in the control of testosterone secretion from rat testis: an overview of our experience.
Topics: 17-alpha-Hydroxyprogesterone; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Androstenedione; Animals; Calcium Signaling; Cells, Cultured; Colforsin; Cyclic AMP; Gene Expression Regulation; Gonadotropin-Releasing Hormone; GTP-Binding Proteins; Leydig Cells; Luteinizing Hormone; Male; Melatonin; Neuroimmunomodulation; Pertussis Toxin; Prolactin; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Second Messenger Systems; Testosterone; Virulence Factors, Bordetella | 2002 |
Receptor (MT(1)) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Biological Transport; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Melatonin; Pancreatic Neoplasms; Phosphodiesterase Inhibitors; Polymerase Chain Reaction; Probenecid; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Signal Transduction; Tryptamines; Tumor Cells, Cultured | 2002 |
Melatonin inhibits insulin secretion and decreases PKA levels without interfering with glucose metabolism in rat pancreatic islets.
Topics: Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Melatonin; Protein Kinase C; Protein Subunits; Rats | 2002 |
Effects of subchronic and chronic melatonin treatment on somatostatin binding and its effects on adenylyl cyclase activity in the rat frontoparietal cortex.
Topics: Adenylyl Cyclases; Animals; Colforsin; Frontal Lobe; Guanylyl Imidodiphosphate; Imidazoles; Melatonin; Parietal Lobe; Rats; Rats, Wistar; Receptors, Somatostatin; Somatostatin | 2002 |
Evidence for the biosynthesis of a prolactin-releasing factor from the ovine pars tuberalis, which is distinct from thyrotropin-releasing hormone.
Topics: Animals; Base Sequence; Cells, Cultured; Chromatography, High Pressure Liquid; Colforsin; Cycloheximide; DNA Primers; Immune Sera; In Situ Hybridization; Melatonin; Pituitary Gland, Anterior; Radioimmunoassay; Sheep; Spectrometry, Mass, Electrospray Ionization; Thyrotropin-Releasing Hormone | 2002 |
Heterocyclic aminopyrrolidine derivatives as melatoninergic agents.
Topics: 3T3 Cells; Aminoquinolines; Animals; Cloning, Molecular; Colforsin; Cyclic AMP; Heterocyclic Compounds; Humans; Kinetics; Ligands; Melatonin; Mice; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Recombinant Proteins; Structure-Activity Relationship | 2003 |
MT-1 melatonin receptor expression increases the antiproliferative effect of melatonin on S-91 murine melanoma cells.
Topics: Animals; Antineoplastic Agents; Binding Sites; Catalase; Cell Division; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Glutathione Peroxidase; GTP-Binding Protein alpha Subunits, Gi-Go; Male; Melanoma; Melatonin; Mice; Mice, Inbred DBA; Receptor, Melatonin, MT1; Signal Transduction; Transfection; Tumor Cells, Cultured | 2004 |
Melatonin signaling dysfunction in adolescent idiopathic scoliosis.
Topics: Adenylyl Cyclases; Adolescent; Cells, Cultured; Colforsin; Cyclic AMP; Female; Guanylyl Imidodiphosphate; Humans; Immunoenzyme Techniques; Male; Melatonin; Osteoblasts; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Scoliosis; Signal Transduction | 2004 |
Intracellular second messengers involved in melatonin signal transduction in chicken splenocytes in vitro.
Topics: Animals; Cell Proliferation; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Inositol 1,4,5-Trisphosphate; Male; Melatonin; Receptor, Melatonin, MT2; Receptors, Melatonin; Second Messenger Systems; Signal Transduction; Spleen; Tetrahydronaphthalenes; Tryptamines | 2004 |
Knock-down of RGS4 and beta tubulin in CHO cells expressing the human MT1 melatonin receptor prevents melatonin-induced receptor desensitization.
Topics: Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cycloheximide; GTP-Binding Protein alpha Subunits; Humans; Melatonin; Receptor, Melatonin, MT1; Reverse Transcriptase Polymerase Chain Reaction; RGS Proteins; RNA, Messenger; Tubulin | 2004 |
Melatonin enhances leptin expression by rat adipocytes in the presence of insulin.
Topics: Adipocytes; Animals; Colforsin; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression; Glucocorticoids; Inhibitory Concentration 50; Insulin; Leptin; Male; Melatonin; Pertussis Toxin; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptor, Insulin; Receptor, Melatonin, MT1; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tryptamines | 2005 |
Melatonin-induced neuropeptide release from isolated locust corpora cardiaca.
Topics: Animals; Chromatography, High Pressure Liquid; Colforsin; Female; Locusta migratoria; Male; Melatonin; Neuropeptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2005 |
Dopamine receptor activation in bovine pinealocyte via a cAMP-dependent transcription pathway.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acyltransferases; Animals; Benzazepines; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Melatonin; Phosphorylation; Pineal Gland; Quinpirole; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Spiperone; Transcription, Genetic | 2005 |
The human MT1 melatonin receptor stimulates cAMP production in the human neuroblastoma cell line SH-SY5Y cells via a calcium-calmodulin signal transduction pathway.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Colforsin; Cyclic AMP; Enzyme Activators; GTP-Binding Proteins; Humans; Melatonin; Neuroblastoma; Neurons; Receptor, Melatonin, MT1; Signal Transduction; Transfection; Tumor Cells, Cultured | 2005 |
17Beta-estradiol modulates hMT1 melatonin receptor function.
Topics: Analysis of Variance; Animals; Blotting, Northern; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Gene Expression Regulation; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Iodine Isotopes; Melatonin; Protein Binding; Radioligand Assay; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfur Isotopes; Time Factors | 2005 |
Rhythmic expression of adenylyl cyclase VI contributes to the differential regulation of serotonin N-acetyltransferase by bradykinin in rat pineal glands.
Topics: Adenylyl Cyclases; Animals; Arylalkylamine N-Acetyltransferase; Blotting, Northern; Bradykinin; Calcium; Chelating Agents; Circadian Rhythm; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Estrenes; Fluorescent Dyes; Fura-2; Gene Expression Regulation, Enzymologic; Immunoblotting; Inositol 1,4,5-Trisphosphate; Ionomycin; Ionophores; Isoproterenol; Male; Melatonin; Norepinephrine; Pertussis Toxin; Phosphodiesterase Inhibitors; Pineal Gland; Protein Isoforms; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Signal Transduction; Superior Cervical Ganglion; Time Factors; Transcriptional Activation; Type C Phospholipases | 2005 |
The avian pineal gland.
Topics: Animals; Biological Clocks; Chickens; Circadian Rhythm; Colforsin; Female; Light; Male; Melatonin; Photoperiod; Pineal Gland; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Signal Transduction | 2006 |
Melatonin modulates acid/base transport in human pancreatic carcinoma cells.
Topics: Acids; Antiporters; Bicarbonates; Biological Transport; Cell Line, Tumor; Colforsin; Cyclic AMP; Gene Expression; Humans; Hydrogen-Ion Concentration; Melatonin; Models, Biological; Pancreatic Neoplasms; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Symporters | 2006 |
Modulation of melatonin receptors and G-protein function by microtubules.
Topics: Animals; Cell Shape; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Heterotrimeric GTP-Binding Proteins; Humans; Melatonin; Microtubules; Protein Kinase C; Receptor, Melatonin, MT1; Rolipram | 2006 |
Molecular determinants of melatonin signaling dysfunction in adolescent idiopathic scoliosis.
Topics: Adenylyl Cyclases; Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Male; Melatonin; Osteoblasts; Protein Kinase C-delta; Receptor, Melatonin, MT2; Receptors for Activated C Kinase; Receptors, Cell Surface; Scoliosis; Signal Transduction | 2007 |
Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Cell Line, Tumor; Colforsin; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide-Gated Cation Channels; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose; Guanylate Cyclase; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Melatonin; Pineal Gland; Rats; Rats, Wistar; Receptor, Melatonin, MT2; Signal Transduction; Tetrahydronaphthalenes; Tryptamines | 2008 |
Sympathetic nervous system modulates the ocular hypotensive action of MT2-melatonin receptors in normotensive rabbits.
Topics: 1-Methyl-3-isobutylxanthine; Administration, Topical; Adrenergic beta-Agonists; Albuterol; Animals; Aqueous Humor; Colforsin; Dose-Response Relationship, Drug; Intraocular Pressure; Isoindoles; Melatonin; Ocular Hypertension; Okadaic Acid; Rabbits; Receptor, Melatonin, MT2; Sympathectomy, Chemical; Sympathetic Nervous System; Terbutaline | 2008 |
Melatonin receptor-mediated protection against myocardial ischaemia/reperfusion injury: role of its anti-adrenergic actions.
Topics: Adrenergic Antagonists; Animals; Colforsin; Cyclic AMP; Guanylate Cyclase; Heart; Indoles; Isoproterenol; Male; Maleimides; Melatonin; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; p38 Mitogen-Activated Protein Kinases; Propranolol; Protein Kinase C; Quinoxalines; Rats; Rats, Wistar; Receptors, Melatonin; Tryptamines | 2008 |
The Galphai and Galphaq proteins mediate the effects of melatonin on steroid/thyroid hormone receptor transcriptional activity and breast cancer cell proliferation.
Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic GMP; Estrogens; Female; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Immunoprecipitation; Luciferases; Melatonin; Phosphorus Radioisotopes; Radioimmunoassay; Receptor, Melatonin, MT1; Receptors, Estrogen; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Retinoic Acid Receptor alpha; Transcription, Genetic; Transfection | 2008 |
An unexpected effect of 5-MCA-NAT in chick retinal development.
Topics: Aging; Animals; Binding Sites; Chick Embryo; Chickens; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Melatonin; Neurogenesis; Neurons; Organ Culture Techniques; Organogenesis; Quinone Reductases; Receptors, G-Protein-Coupled; Receptors, Melatonin; Retina; Second Messenger Systems; Tryptamines; Up-Regulation | 2009 |
Transcripts of calcium/calmodulin-dependent kinases are changed after forskolin- or IBMX-induced insulin secretion due to melatonin treatment of rat insulinoma beta-cells (INS-1).
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Tumor; Colforsin; Gene Expression Regulation, Developmental; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Islets of Langerhans; Melatonin; Rats; Rats, Wistar | 2009 |
Hypothalamic gonadotropin-releasing hormone receptor activation stimulates oxytocin release from the rat hypothalamo-neurohypophysial system while melatonin inhibits this process.
Topics: Animals; Colforsin; Cyclic AMP; Gonadotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Hypothalamus; In Vitro Techniques; Male; Melatonin; Neurons; Oxytocin; Rats; Rats, Wistar; Receptors, LHRH; Signal Transduction | 2010 |
Expression of functional melatonin MT(1) receptors in equine luteal cells: in vitro effects of melatonin on progesterone secretion.
Topics: Animals; Blotting, Western; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Colforsin; Female; Horses; Luteal Cells; Melatonin; Ovarian Follicle; Progesterone; Receptor, Melatonin, MT1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Statistics, Nonparametric; Tryptamines | 2011 |
Phosphorylation of cyclic AMP-response element-binding protein (CREB) is influenced by melatonin treatment in pancreatic rat insulinoma β-cells (INS-1).
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Tumor; Colforsin; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Humans; Insulin-Secreting Cells; Insulinoma; Melatonin; Microscopy, Confocal; Pancreatic Neoplasms; Phosphorylation; Rats; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Signal Transduction; Tetrahydronaphthalenes; Time Factors; Transfection; Tryptamines | 2012 |
2-Arachidonoyl glycerol sensitizes the pars distalis and enhances forskolin-stimulated prolactin secretion in Syrian hamsters.
Topics: Animals; Arachidonic Acids; Cells, Cultured; Circadian Rhythm; Colforsin; Cricetinae; Endocannabinoids; Glycerides; Male; Melatonin; Photoperiod; Pituitary Gland; Prolactin | 2014 |
Forskolin-stimulated vasopressin and oxytocin release from the rat hypothalamo-neurohypophysial system in vitro is inhibited by melatonin.
Topics: Animals; Colforsin; Cyclic AMP; Hypothalamo-Hypophyseal System; In Vitro Techniques; Male; Melatonin; Oxytocin; Pituitary Gland; Rats; Rats, Wistar; Vasopressins | 2014 |
In vitro comparison of duration of action of melatonin agonists on melatonin MT1 receptor: possible link between duration of action and dissociation rate from receptor.
Topics: Animals; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Extracellular Signal-Regulated MAP Kinases; Humans; Kinetics; Melatonin; Phosphorylation; Rats; Receptor, Melatonin, MT1 | 2015 |
The role of the cAMP/PKA signalling pathway in the inhibitory influence of melatonin on oxytocin and vasopressin secretion from the rat hypothalamo-neurohypophysial system.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Hypothalamo-Hypophyseal System; Male; Melatonin; Oxytocin; Rats; Rats, Wistar; Signal Transduction; Vasopressins | 2018 |
Cryptochrome deficiency enhances transcription but reduces protein levels of pineal Aanat
Topics: Animals; Blotting, Western; Circadian Rhythm; Colforsin; Cryptochromes; Cyclic AMP; Melatonin; Mice; Period Circadian Proteins; Pineal Gland; Transcription, Genetic | 2018 |
Melatonin Signaling Pathways Implicated in Metabolic Processes in Human Granulosa Cells (KGN).
Topics: Colforsin; Female; Follicular Atresia; Granulosa Cells; Humans; Melatonin; Signal Transduction | 2022 |
Melatonin inhibits muscular-mucosal stretch-sensitive bladder afferents via the MT2 receptors.
Topics: Animals; Colforsin; Guinea Pigs; Melatonin; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Urinary Bladder | 2022 |
Effects of cyclic adenosine monophosphate modulating agents during oocyte pre-maturation and the role of melatonin on in vitro maturation of bovine cumulus-oocyte complexes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Monophosphate; Animals; Cattle; Colforsin; Cumulus Cells; Cyclic AMP; Female; In Vitro Oocyte Maturation Techniques; Melatonin; Natriuretic Peptide, C-Type; Oocytes; RNA, Messenger; Superoxide Dismutase | 2023 |