melatonin has been researched along with caffeine in 71 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (4.23) | 18.7374 |
| 1990's | 7 (9.86) | 18.2507 |
| 2000's | 23 (32.39) | 29.6817 |
| 2010's | 24 (33.80) | 24.3611 |
| 2020's | 14 (19.72) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Arce, MP; Conde, S; Egea, J; Gil, C; León, R; López, MG; Monjas, L; Pérez, C; Rodríguez-Franco, MI; Villarroya, M | 1 |
| Atkinson, BN; Bayle, ED; Fish, PV; Steadman, D; Svensson, F; Vincent, JP; Whiting, P; Willis, NJ; Woodward, HL | 1 |
| Buhrley, LE; Ellis, LC; Sorenson, DK | 1 |
| Bagnara, JT; Hadley, ME | 1 |
| Heath, JR; Zatz, M | 1 |
| Babey, AM; Palmour, RM; Young, SN | 1 |
| Fauteck, JD; Fischer, B; Madeja, M; Musshoff, U; Speckmann, EJ; Wittkowski, W | 1 |
| Badia, P; Hakel, M; Myers, BL; Plenzler, SC; Wright, KP | 1 |
| Lagarde, D | 1 |
| Doireau, P; Lagarde, D | 1 |
| Badia, P; Drake, CL; Myers, BL; Plenzler, SC; Wright, KP | 1 |
| Billaud, PF; Chappuis, B; Chauffard, F; French, J; Lagarde, D; Ramont, L | 1 |
| Bertilsson, L; Christensen, M; Härtter, S; Morita, S; Röjdmark, S; Tybring, G; Ursing, C; von Bahr, C | 1 |
| Beaumont, M; Chauffard, F; Coste, O; Enslen, M; Fontan, A; French, J; Lagarde, D; Piérard, C; Reiter, RJ; Tan, DX | 1 |
| Sparaco, P | 1 |
| Babkoff, H; French, J; Sutherlin, R; Whitmore, J | 1 |
| Bertilsson, L; Härtter, S; Röjdmark, S; Tybring, G; Ursing, C; von Bahr, C | 1 |
| Lieberman, HR | 1 |
| Brismar, K; Röjdmark, S; Ursing, C; Wikner, J | 1 |
| Batéjat, D; Beaumont, M; Chauffard, F; Coste, O; Denis, JB; Doireau, P; French, J; Lagarde, D; Piérard, C; Van Beers, P | 1 |
| MALAWISTA, SE | 1 |
| Heath, J; Straume, M; Yadav, G; Zatz, M | 1 |
| Bertilsson, L; Härtter, S; Laine, K; Nordmark, A; Rose, DM; Tybring, G | 1 |
| Cajochen, C; Czeisler, CA; Dijk, DJ; Ritz-De Cecco, A; Wyatt, JK | 1 |
| Edwards, B; Reilly, T; Waterhouse, J | 1 |
| Cajochen, Ch | 1 |
| Härtter, S; Korhonen, T; Laine, K; Lundgren, S; Rane, A; Tolonen, A; Turpeinen, M | 1 |
| Roth, T; Schwartz, JR | 1 |
| Baron, JA; Comi, R; Keisari, R; Kim, J; Larson, R; MacKenzie, T; Manwar, S; Sluss, P | 1 |
| Camello, PJ; Gomez-Pinilla, PJ; Pozo, MJ | 1 |
| Coste, O; Lagarde, D | 1 |
| Herxheimer, A | 1 |
| Myslobodsky, M | 1 |
| Holle, D; Obermann, M | 1 |
| Auger, RR; Kolla, BP | 1 |
| Igaz, P; Tulassay, Z | 1 |
| Amali, OO; Obochi, GO; Ochalefu, DO | 1 |
| Samuels, CH | 1 |
| Ong, JC; Park, M | 1 |
| Arendash, GW; Bradshaw, PC; Cao, C; Copes, N; Delic, V; Dragicevic, N; Lin, X; Mamcarz, M; Wang, L | 1 |
| Aitken, RJ; Jones, KT; Lord, T; Nixon, B | 1 |
| Boakye, CH; Etukala, JR; Marepally, S; Shah, PP; Singh, M; Vemuri, A | 1 |
| Famenini, S; Goh, C | 1 |
| Costa, G; Driscoll, TR; Isotalo, LK; Liira, J; Ruotsalainen, JH; Sallinen, M; Verbeek, JH | 1 |
| Cao, C; Du, YH; He, ZX; Wang, ZH; Zhang, LF; Zhou, SF; Zhou, ZW | 1 |
| Lockley, SW; St Hilaire, MA | 1 |
| Bessman, SC; Burke, TM; Chinoy, ED; Jung, CM; Markwald, RR; McHill, AW; O'Neill, JS; Snider, JA; Wright, KP | 1 |
| Banks, S; Dorrian, J; Hilditch, CJ | 1 |
| Byun, S; Han, JW; Kim, KW; Kim, T; Lee, JR; Park, J; Suh, SW; Yoon, IY | 1 |
| Burke, LM; Halson, SL; Pearce, J | 1 |
| Chuproski, AP; D Dos Santos, P; D Noseda, AC; D S Targa, A; Fagotti, J; L Ilkiwa, J; M S Lima, M; Rodrigues, LS; W C Dorieux, F | 1 |
| Drevet, JR; Evenson, DP; Hallak, J; Monteiro, RAC; Pariz, JR; Ranéa, C | 1 |
| Borgwardt, S; Cajochen, C; Garbazza, C; Kistler, J; Kolodyazhniy, V; Landolt, HP; Lin, YS; Rehm, S; Reichert, CF; Rentsch, K; Weibel, J | 1 |
| Haber, JJ; Wallace, PJ | 1 |
| Benetti, C; Bose, A; Chong, PW; Colombo, P; Razali, S; Wong, TW | 1 |
| Ahammed, GJ; Deng, WW; Fu, JY; Han, WY; Li, MH; Li, X; Wei, JP; Yan, P; Zhang, LP | 1 |
| Akyüz, E; Arıkan, ES; Ertekin, T; Göçmen, AY; Güler, H; Nisari, M; Sabitaliyevich, UY; Tokpınar, A; Unur, E; Yalçın, B; Yay, AH; Yılmaz, H; Yılmaz, S | 1 |
| Deka, A; Fogg, LF; Gottlieb, M; Kravitz, HM; Sholtes, D; Westrick, J | 1 |
| Bühler, M; Deuring, G; Garbazza, C; Gruber, G; Lin, YS; Meyer, M; Rehm, SS; Reichert, CF; Rentsch, K; Slawik, H; Veitz, S; Weibel, J | 1 |
| Daali, Y; Desmeules, J; Magliocco, G; Samer, CF; Thomas, A | 1 |
| Benetti, C; Bose, A; Chong, PW; Colombo, G; Colombo, P; Miller, M; Razali, S; Wong, TW | 1 |
| Fatarova, M; Guy, PA; Hoeng, J; Ivanov, NV; Kuczaj, A; Laszlo, C; Majeed, S; Mazurov, A; Pak, C; Peitsch, MC; Steiner, S; Vidal-de-Miguel, G; Zivkovic Semren, T | 1 |
| Antonijevic, MD; Derrar, Y; Douroumis, D; Grau, C; Katsamenis, OL; Mithu, MS; Morales, A; Tabriz, AG; Vilain, L | 1 |
| Bernis, ME; Imam, FB; Maes, E; Maltepe, E; Pang, R; Pasca, AM; Robertson, NJ; Sabir, H; Schleehuber, Y; Silverman, J; White, Y; Zweyer, M | 1 |
| Azevedo, LM; Bicalho, EM; Carvalho, GR; de Andrade, FHA; de Oliveira Santos, M; de Resende, MLV; Ferreira, AMO; Silva, VA | 1 |
17 review(s) available for melatonin and caffeine
| Article | Year |
|---|---|
[Role of the pharmacopoeia in the prevention of jet-lag].
Topics: Caffeine; Central Nervous System Stimulants; Chronotherapy; Circadian Rhythm; Humans; Hypnotics and Sedatives; Melatonin; Sleep Wake Disorders; Travel | 1997 |
[Jet lag].
Topics: Caffeine; Central Nervous System Stimulants; Circadian Rhythm; Humans; Hypnotics and Sedatives; Melatonin; Psychomotor Performance; Risk Factors; Sunlight; Travel | 1997 |
Nutrition, brain function and cognitive performance.
Topics: Adult; Brain; Caffeine; Cognition; Dietary Carbohydrates; Dietary Proteins; Humans; Melatonin; Nutritional Physiological Phenomena; Tryptophan; Tyrosine | 2003 |
Jet lag and air travel: implications for performance.
Topics: Aircraft; Caffeine; Central Nervous System Stimulants; Circadian Rhythm; Female; Humans; Hypnotics and Sedatives; Jet Lag Syndrome; Male; Melatonin; Phototherapy; Psychomotor Performance; Sports; Sports Medicine; Travel | 2005 |
[Sleep disruption in shift work and jet lag: the role of the circadian timing system].
Topics: Adult; Antioxidants; Caffeine; Central Nervous System Stimulants; Circadian Rhythm; Humans; Hypnotics and Sedatives; Jet Lag Syndrome; Melatonin; Sleep; Sleep Disorders, Circadian Rhythm; Time Factors; Work Schedule Tolerance | 2005 |
Shift work sleep disorder: burden of illness and approaches to management.
Topics: Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Circadian Rhythm; Cost of Illness; Exercise Therapy; Humans; Hypnotics and Sedatives; Melatonin; Modafinil; Phototherapy; Quality of Life; Sleep; Sleep Disorders, Circadian Rhythm; Wakefulness | 2006 |
Clinical management of jet lag: what can be proposed when performance is critical?
Topics: Aircraft; Caffeine; Central Nervous System Stimulants; Chronobiology Phenomena; Circadian Rhythm; Humans; Hypnotics and Sedatives; Jet Lag Syndrome; Melatonin; Travel | 2009 |
Jet lag.
Topics: Air Travel; Azabicyclo Compounds; Caffeine; Humans; Hypnotics and Sedatives; Jet Lag Syndrome; Melatonin; Saliva | 2008 |
The paradox of caffeine-zolpidem interaction: a network analysis.
Topics: Animals; Antioxidants; Caffeine; Central Nervous System Stimulants; Drug Synergism; Humans; Hypnotics and Sedatives; Melatonin; Pyridines; Reactive Oxygen Species; Software; Zolpidem | 2009 |
Hypnic headache.
Topics: Antidepressive Agents; Caffeine; Central Nervous System Stimulants; Cyclooxygenase Inhibitors; Headache Disorders, Primary; Humans; Indomethacin; Melatonin | 2010 |
Jet lag and shift work sleep disorders: how to help reset the internal clock.
Topics: Actigraphy; Age Factors; Benzodiazepines; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Humans; Hypnotics and Sedatives; Jet Lag Syndrome; Light; Lighting; Melatonin; Monitoring, Physiologic; Sleep; Sleep Disorders, Circadian Rhythm; Travel | 2011 |
Chronic headaches and insomnia: working toward a biobehavioral model.
Topics: Actigraphy; Adaptation, Psychological; Caffeine; Chronobiology Phenomena; Comorbidity; Headache Disorders; Humans; Hypnotics and Sedatives; Melatonin; Migraine Disorders; Models, Neurological; Models, Psychological; Polysomnography; Self Report; Sleep Initiation and Maintenance Disorders; Sleep Stages; Tension-Type Headache; Wakefulness | 2012 |
Pharmacological interventions for sleepiness and sleep disturbances caused by shift work.
Topics: Azabicyclo Compounds; Benzhydryl Compounds; Caffeine; Humans; Hypnotics and Sedatives; Melatonin; Modafinil; Piperazines; Randomized Controlled Trials as Topic; Sleep; Sleep Disorders, Circadian Rhythm; Wakefulness; Wakefulness-Promoting Agents | 2014 |
Time to wake up: reactive countermeasures to sleep inertia.
Topics: Caffeine; Humans; Light; Melatonin; Sleep; Sound; Temperature; Time Factors; Wakefulness | 2016 |
Nutrition for Travel: From Jet lag To Catering.
Topics: Athletes; Caffeine; Humans; Jet Lag Syndrome; Light; Meals; Melatonin; Sports Nutritional Physiological Phenomena; Time Factors; Travel | 2019 |
Potential new therapies against a toxic relationship: neuroinflammation and Parkinson's disease.
Topics: Animals; Anti-Inflammatory Agents; Caffeine; Cannabinoids; Dietary Supplements; Humans; Melatonin; Neuroimmunomodulation; Parkinson Disease | 2019 |
Optimising sleep and performance during night float: A systematic review of evidence and implications for graduate medical education trainees.
Topics: Adaptation, Physiological; Attention; Caffeine; Education, Medical, Graduate; Energy Drinks; Fatigue; Humans; Melatonin; Modafinil; Reaction Time; Sleep; Sleep Deprivation; Sleep Disorders, Circadian Rhythm; Work Schedule Tolerance | 2021 |
14 trial(s) available for melatonin and caffeine
| Article | Year |
|---|---|
Caffeine and light effects on nighttime melatonin and temperature levels in sleep-deprived humans.
Topics: Adolescent; Adult; Body Temperature; Caffeine; Central Nervous System Stimulants; Depression, Chemical; Humans; Light; Male; Melatonin; Sleep Deprivation | 1997 |
Acute effects of bright light and caffeine on nighttime melatonin and temperature levels in women taking and not taking oral contraceptives.
Topics: Adolescent; Adult; Body Temperature; Caffeine; Circadian Rhythm; Contraceptives, Oral; Drug Interactions; Female; Humans; Melatonin; Photic Stimulation; Time Factors | 2000 |
Evaluation of pharmacological aids on physical performance after a transmeridian flight.
Topics: Adult; Analysis of Variance; Antioxidants; Caffeine; Central Nervous System Stimulants; Circadian Rhythm; Delayed-Action Preparations; Double-Blind Method; Exercise Test; Female; Hand Strength; Humans; Jet Lag Syndrome; Male; Melatonin; Middle Aged | 2001 |
Resynchronization of hormonal rhythms after an eastbound flight in humans: effects of slow-release caffeine and melatonin.
Topics: Adjuvants, Immunologic; Adult; Caffeine; Central Nervous System Stimulants; Delayed-Action Preparations; Female; Humans; Hydrocortisone; Jet Lag Syndrome; Male; Melatonin; Middle Aged; Saliva | 2001 |
Single-dose bright light and/or caffeine effect on nocturnal performance.
Topics: Adult; Arousal; Body Temperature; Caffeine; Female; Humans; Lighting; Male; Melatonin; Reaction Time; Saliva; Space Perception; Task Performance and Analysis; Visual Perception | 2002 |
Caffeine raises the serum melatonin level in healthy subjects: an indication of melatonin metabolism by cytochrome P450(CYP)1A2.
Topics: Caffeine; Capsules; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Female; Humans; Male; Melatonin; Reference Values | 2003 |
Caffeine or melatonin effects on sleep and sleepiness after rapid eastward transmeridian travel.
Topics: Adult; Anticonvulsants; Body Temperature; Caffeine; Central Nervous System Stimulants; Female; Humans; Jet Lag Syndrome; Male; Melatonin; Middle Aged; Sleep; Sleep Stages | 2004 |
Effects of caffeine intake on the pharmacokinetics of melatonin, a probe drug for CYP1A2 activity.
Topics: Administration, Oral; Adolescent; Adult; Caffeine; Cross-Over Studies; Cytochrome P-450 CYP1A2; Drug Combinations; Female; Heterozygote; Homozygote; Humans; Male; Melatonin | 2003 |
Low-dose repeated caffeine administration for circadian-phase-dependent performance degradation during extended wakefulness.
Topics: Adolescent; Adult; Body Temperature; Caffeine; Central Nervous System Stimulants; Circadian Rhythm; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Female; Homeostasis; Humans; Male; Melatonin; Periodicity; Polysomnography; Severity of Illness Index; Sleep; Sleep Disorders, Circadian Rhythm; Wakefulness | 2004 |
Metabolic and hormonal effects of caffeine: randomized, double-blind, placebo-controlled crossover trial.
Topics: Adult; Androstenedione; Blood Glucose; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Dehydroepiandrosterone; Double-Blind Method; Female; Humans; Hydrocortisone; Insulin; Male; Melatonin; Salivary Glands | 2007 |
Caffeine does not entrain the circadian clock but improves daytime alertness in blind patients with non-24-hour rhythms.
Topics: Affect; Aged; Arousal; Blindness; Caffeine; Circadian Clocks; Humans; Male; Melatonin; Middle Aged; Polysomnography; Sleep Disorders, Circadian Rhythm | 2015 |
Effects of caffeine on the human circadian clock in vivo and in vitro.
Topics: Adult; Analysis of Variance; Biosensing Techniques; Caffeine; Cell Line, Tumor; Circadian Clocks; Circadian Rhythm; Cyclic AMP; Dose-Response Relationship, Drug; Double-Blind Method; Female; Healthy Volunteers; Humans; Luminescence; Male; Melatonin; RNA, Small Interfering; Young Adult | 2015 |
Melatonin and Caffeine Supplementation Used, Respectively, as Protective and Stimulating Agents in the Cryopreservation of Human Sperm Improves Survival, Viability, and Motility after Thawing compared to Traditional TEST-Yolk Buffer.
Topics: Adult; Buffers; Caffeine; Cell Survival; Cryopreservation; Humans; Male; Melatonin; Middle Aged; Reactive Oxygen Species; Sperm Motility; Spermatozoa | 2019 |
Wide awake at bedtime? Effects of caffeine on sleep and circadian timing in male adolescents - A randomized crossover trial.
Topics: Adolescent; Brain; Caffeine; Central Nervous System Stimulants; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Humans; Male; Melatonin; Saliva; Sleep; Wakefulness | 2021 |
40 other study(ies) available for melatonin and caffeine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Donepezil; Glutamates; Hippocampus; Humans; Indans; Neuroprotective Agents; Piperidines; Rats; Solid-Phase Synthesis Techniques | 2017 |
Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling.
Topics: Binding Sites; Catalytic Domain; Cell Nucleus; Cytoplasm; Enzyme Inhibitors; Esterases; Humans; Molecular Dynamics Simulation; Small Molecule Libraries; Wnt Signaling Pathway | 2021 |
Mechanisms and interactions in testicular steroidogenesis and prostaglandin synthesis.
Topics: Adrenal Glands; Adrenal Medulla; Adrenalectomy; Animals; Bucladesine; Caffeine; Cyclic AMP; Hydrocortisone; Hypophysectomy; Lipid Metabolism; Male; Melatonin; Muscle Contraction; Peroxidases; Pituitary Gland; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Serotonin; Steroids; Testis | 1975 |
Integrated nature of chromatophore responses in the in vitro frog skin bioassay.
Topics: Acetylcholine; Animals; Anura; Biological Assay; Caffeine; Chromatophores; Female; In Vitro Techniques; Male; Melanins; Melanocyte-Stimulating Hormones; Melatonin; Norepinephrine; Photometry; Pigmentation; Skin; Stimulation, Chemical | 1969 |
Calcium and photoentrainment in chick pineal cells revisited: effects of caffeine, thapsigargin, EGTA, and light on the melatonin rhythm.
Topics: Animals; Caffeine; Calcium; Cells, Cultured; Chickens; Circadian Rhythm; Egtazic Acid; Light; Melatonin; Pineal Gland; Terpenes; Thapsigargin | 1995 |
Caffeine and propranolol block the increase in rat pineal melatonin production produced by stimulation of adenosine receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analysis of Variance; Animals; Binding, Competitive; Caffeine; Caudate Nucleus; Circadian Rhythm; Male; Melatonin; Pineal Gland; Propranolol; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Vasodilator Agents | 1994 |
Expression and functional characterization of a melatonin-sensitive receptor in Xenopus oocytes.
Topics: Animals; Anthracenes; Autoradiography; Binding Sites; Brain; Caffeine; Colforsin; Cyclic AMP; Female; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Melatonin; Membrane Potentials; Microinjections; Oocytes; Patch-Clamp Techniques; Pertussis Toxin; Rats; Receptors, Cell Surface; Receptors, Melatonin; RNA, Messenger; Virulence Factors, Bordetella | 1996 |
Orally given melatonin may serve as a probe drug for cytochrome P450 1A2 activity in vivo: a pilot study.
Topics: Administration, Oral; Adult; Caffeine; Cytochrome P-450 CYP1A2; Female; Humans; Male; Melatonin; Phenotype; Pilot Projects; Reference Values; Time Factors | 2001 |
Combating fatigue to enhance safety.
Topics: Accidents, Aviation; Aerospace Medicine; Caffeine; Circadian Rhythm; Ergonomics; Fatigue; Humans; Melatonin; Occupational Health; Personnel Staffing and Scheduling; Sleep Deprivation; Task Performance and Analysis; Work Schedule Tolerance; Workload | 1996 |
Does hepatic metabolism of melatonin affect the endogenous serum melatonin level in man?
Topics: Adult; Aged; Area Under Curve; Caffeine; Cytochrome P-450 CYP1A2; Female; Humans; Liver; Male; Melatonin; Middle Aged | 2002 |
ON THE ACTION OF COLCHICINE, THE MELANOCYTE MODEL.
Topics: Acetates; Animals; Anura; Caffeine; Cell Division; Chromatophores; Colchicine; Cytoplasm; Gout; Hydrocortisone; Melanocyte-Stimulating Hormones; Melanocytes; Melatonin; Models, Theoretical; Norepinephrine; Pharmacology; Research; Skin | 1965 |
Are changes in MAPK/ERK necessary or sufficient for entrainment in chick pineal cells?
Topics: Acetylserotonin O-Methyltransferase; Animals; Blood Proteins; Caffeine; Cells, Cultured; Central Nervous System Stimulants; Chickens; Circadian Rhythm; Darkness; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Imidazoles; Light; Melatonin; Mitogen-Activated Protein Kinases; Osmolar Concentration; Pineal Gland; Pyridines | 2003 |
[Strategies against jet lag].
Topics: Anti-Anxiety Agents; Caffeine; Central Nervous System Stimulants; Complementary Therapies; Homeopathy; Humans; Jet Lag Syndrome; Melatonin; Time Factors; Triazolam | 2004 |
Effect of caffeine intake 12 or 24 hours prior to melatonin intake and CYP1A2*1F polymorphism on CYP1A2 phenotyping by melatonin.
Topics: Administration, Oral; Adolescent; Adult; Caffeine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Female; Humans; Male; Melatonin; Polymorphism, Genetic | 2006 |
Protective effect of melatonin on Ca2+ homeostasis and contractility in acute cholecystitis.
Topics: Acalculous Cholecystitis; Animals; Caffeine; Calcium; Cholecystitis, Acute; Common Bile Duct; Disease Models, Animal; Gallbladder; Guinea Pigs; Homeostasis; Ligation; Lipid Peroxidation; Male; Melatonin; Muscle Contraction; Nitrendipine; Pinacidil; Thapsigargin | 2008 |
[Clinical picture and treatment of jet lag].
Topics: Benzhydryl Compounds; Biological Clocks; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Circadian Rhythm; Humans; Jet Lag Syndrome; Melatonin; Modafinil; Sleep | 2011 |
Effect of melatonin and caffeine interaction on caffeine induced oxidative stress and sleep disorders.
Topics: Animals; Caffeine; Drug Combinations; Drug Interactions; Melatonin; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Sleep Wake Disorders; Treatment Outcome | 2010 |
Jet lag and travel fatigue: a comprehensive management plan for sport medicine physicians and high-performance support teams.
Topics: Athletes; Athletic Performance; Caffeine; Circadian Rhythm; Fatigue; Humans; Hypnotics and Sedatives; Jet Lag Syndrome; Melatonin; Physicians; Sports Medicine; Workforce | 2012 |
Caffeine increases mitochondrial function and blocks melatonin signaling to mitochondria in Alzheimer's mice and cells.
Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antioxidants; Caffeine; Cells, Cultured; Central Nervous System Stimulants; Cyclic AMP; Cyclic GMP; Enzyme-Linked Immunosorbent Assay; In Vitro Techniques; Melatonin; Membrane Potential, Mitochondrial; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Diseases; Neurons; Oxygen Consumption; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Reactive Oxygen Species; Signal Transduction; Transfection | 2012 |
Melatonin prevents postovulatory oocyte aging in the mouse and extends the window for optimal fertilization in vitro.
Topics: Animals; Antioxidants; Apoptosis; Caffeine; Cellular Senescence; Drug Evaluation, Preclinical; Female; Fertilization in Vitro; Melatonin; Mice; Mice, Inbred C57BL; Oocytes; Oxidative Stress; Phosphodiesterase Inhibitors | 2013 |
Design, synthesis of novel lipids as chemical permeation enhancers and development of nanoparticle system for transdermal drug delivery.
Topics: alpha-MSH; Animals; Caffeine; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Delivery Systems; Estradiol; Ethanol; Humans; Lipids; Melatonin; Nanoparticles; Permeability; Rats; Skin; Substance P | 2013 |
Evidence for supplemental treatments in androgenetic alopecia.
Topics: Alopecia; Biological Products; Biotin; Caffeine; Female; Humans; Male; Melatonin; Zinc | 2014 |
Coffee and caffeine potentiate the antiamyloidogenic activity of melatonin via inhibition of Aβ oligomerization and modulation of the Tau-mediated pathway in N2a/APP cells.
Topics: Amyloid beta-Peptides; Animals; Caffeine; Cell Survival; Coffee; Dose-Response Relationship, Drug; Melatonin; Mice; Molecular Docking Simulation; Protein Aggregation, Pathological; Protein Multimerization; Structure-Activity Relationship; tau Proteins; Tumor Cells, Cultured | 2015 |
Lifetime coffee consumption, pineal gland volume, and sleep quality in late life.
Topics: Aged; Aged, 80 and over; Caffeine; Coffee; Cognition; Dementia; Female; Humans; Imaging, Three-Dimensional; Linear Models; Longitudinal Studies; Male; Melatonin; Middle Aged; Pineal Gland; Sleep | 2018 |
Caffeine-dependent changes of sleep-wake regulation: Evidence for adaptation after repeated intake.
Topics: Adaptation, Physiological; Adolescent; Adult; Caffeine; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Humans; Hydrocortisone; Male; Melatonin; Saliva; Sleep; Wakefulness; Young Adult | 2020 |
Top 10 evidence-based countermeasures for night shift workers.
Topics: Caffeine; Circadian Rhythm; Eating; Efficiency; Emergency Service, Hospital; Fatigue; Female; Humans; Lighting; Male; Melatonin; Personnel Staffing and Scheduling; Quality of Life; Sleep Deprivation; Temperature; Work Schedule Tolerance | 2020 |
Design of multi-particulate "Dome matrix" with sustained-release melatonin and delayed-release caffeine for jet lag treatment.
Topics: Animals; Caffeine; Delayed-Action Preparations; Jet Lag Syndrome; Melatonin; Polymers; Rats; Solubility | 2020 |
Exogenous melatonin improves tea quality under moderate high temperatures by increasing epigallocatechin-3-gallate and theanine biosynthesis in Camellia sinensis L.
Topics: Caffeine; Camellia sinensis; Catechin; Climate; Glutamates; Melatonin; Photosynthesis; Plant Leaves; Tea; Temperature | 2020 |
The protective role of melatonin against the effects of different doses of caffeine on the fetus.
Topics: Animals; Antioxidants; Biomarkers; Bone and Bones; Caffeine; Female; Fetus; Inflammation; Liver; Male; Melatonin; Placenta; Pregnancy; Protective Agents; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Up-Regulation | 2020 |
Evaluation of CYP1A2 activity: Relationship between the endogenous urinary 6-hydroxymelatonin to melatonin ratio and paraxanthine to caffeine ratio in dried blood spots.
Topics: Caffeine; Cytochrome P-450 CYP1A2; Dried Blood Spot Testing; Humans; Melatonin; Theophylline | 2022 |
Advanced Dome cellulose/alginate/chitosan composite matrix design with gastric and intestinal co-targeting capacities.
Topics: Alginates; Caffeine; Cellulose; Chitosan; Hexuronic Acids; Melatonin; Stomach | 2022 |
Application of Secondary Electrospray Ionization Coupled with High-Resolution Mass Spectrometry in Chemical Characterization of Thermally Generated Aerosols.
Topics: Aerosols; Azithromycin; Caffeine; Cannabidiol; Hydroxychloroquine; Melatonin; Spectrometry, Mass, Electrospray Ionization; Vitamin B 12 | 2022 |
3D printing of LEGO® like designs with tailored release profiles for treatment of sleep disorder.
Topics: Caffeine; Drug Liberation; Humans; Melatonin; Printing, Three-Dimensional; Sleep Wake Disorders; Tablets; Technology, Pharmaceutical | 2023 |
Comparing the efficacy in reducing brain injury of different neuroprotective agents following neonatal hypoxia-ischemia in newborn rats: a multi-drug randomized controlled screening trial.
Topics: Allopurinol; Animals; Animals, Newborn; Asphyxia Neonatorum; Brain; Brain Injuries; Caffeine; Clemastine; Disease Models, Animal; Hedgehog Proteins; Humans; Hydroxybutyrates; Hypothermia, Induced; Hypoxia; Hypoxia-Ischemia, Brain; Infant, Newborn; Ischemia; Melatonin; Neuroprotective Agents; Rats | 2023 |
IBA and melatonin increase trigonelline and caffeine during the induction and initiation of adventitious roots in Coffea arabica L. cuttings.
Topics: Antioxidants; Caffeine; Coffea; Hydrogen Peroxide; Melatonin; Phenols | 2023 |