Compounds > melatonin

melatonin and acetylcysteine

melatonin has been researched along with acetylcysteine in 70 studies

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's34 (48.57)29.6817
2010's29 (41.43)24.3611
2020's7 (10.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
de Los Ríos, C; Egea, J; Gálvez, E; García, AG; Iriepa, I; León, R; López, MG; Marco-Contelles, J; Moraleda, I; Romero, A; Samadi, A; Villarroya, M1
Ekins, S; Williams, AJ; Xu, JJ1
Bartolomé, B; Chioua, M; García, AG; Garrido, I; González-Lafuente, L; Ismaili, L; Marco-Contelles, J; Oset-Gasque, MJ; Revuelta, J; Samadi, A; Soriano, E; Tomassolli, I; Valderas, C; Villarroya, M1
Finkin-Groner, E; Ginsburg, I; Lerman, L; Nudelman, A; Shalom, H; Weill, T; Weinstock, M; Yanovsky, I; Zaikin, A; Zeeli, S1
Besner, JG; Bouchard, JF; Cabassi, A; de Champlain, J; Dumont, EC; Girouard, H; Lamontagne, D; Le Jossec, M1
Besséde, G; Gambert, P; Gueldry, S; Lizard, G; Miguet, C; Monier, S; Neel, D1
Herman, TS; Martinez, BR; Meltz, ML; Mohan, S; Natarajan, M1
Bershteĭn, LM; Bychkova, NV; Gamaiunova, VB; Kalinina, NM; Kovalenko, IG; Kriuchkova, OG; Poroshina, TE; Tsyrlina, EV; Vasil'ev, DA1
Antolín, I; Herrera, F; Martín, V; Mayo, JC; Rodriguez, C; Sainz, RM1
Bershtein, LM; Gamayunova, VB; Ivanov, SD; Kalinina, NM; Kovalenko, IG; Poroshina, TE; Solntseva, OS; Tsyrlina, EV; Vasil'ev, DA1
Dirden, JC; Fukuhara, C; Tosini, G1
Brown, AD; Chaurasia, SS; Haque, R; Iuvone, PM; Klein, DC; Ma, M; Weller, J; Zawilska, JB1
Suntres, ZE1
Chulak, C; de Champlain, J; Girouard, H; Lamontagne, D; LeJossec, M1
Arbak, S; Ayanoğlu-Dülger, G; Ersoy, Y; Kaçmaz, A; Sehirli, AO; Sener, G; Tosun, O1
Bershtein, LM; Gamayunova, VB; Kovalenko, IG; Poroshina, TE; Rozanov, YM; Tsyrlina, EV; Vasil'ev, DA1
Ayanoğlu-Dülger, G; Sehirli, AO; Sener, G2
Bershteĭn, LM; Kovalenko, IG; Poroshina, TE; Tsyrlina, EV; Vasil'ev, DA1
Andreadou, I; Bofilis, E; Constantinou, M; Iliodromitis, EK; Kremastinos, DT; Mikros, E; Tsantili-Kakoulidou, A; Zoga, A1
Bryla, J; Drozak, J; Fraczyk, T; Kiersztan, A; Przedlacka, M; Wegrzynowicz, M; Winiarska, K1
Chulak, C; de Champlain, J; Denault, C; Girouard, H1
Flora, SJ; Kannan, GM; Mehta, A; Pande, M1
Allshire, A; Anoopkumar-Dukie, S; Carey, JB; Conere, T1
Liu, XJ; Zhao, J1
Liu, XJ; Sun, WM; Tang, XL; Zhao, J; Zheng, RL1
Bryla, J; Drozak, J; Fraczyk, T; Malinska, D; Winiarska, K1
Ates, B; Batçioğlu, K; Eşrefoğlu, M; Gül, M; Selimoğlu, MA1
Huang, D; Liu, J; Liu, Y; Zhang, Y1
Dobesová, Z; Dovinová, I; Jendeková, L; Kojsová, S; Kunes, J; Paulis, L; Pechánová, O; Simko, F; Sládková, M; Zenebe, W; Zicha, J1
Flora, G; Flora, SJ; Mishra, M; Saxena, G1
Dong, G; Feng, X; Huang, H; Jing, H; Li, D; Sheng, Y; Wang, C; Yin, R; Zhu, J1
Duydu, Y; Ustundag, A1
Bhadauria, S; Flora, SJ; Kannan, GM; Singh, N1
Eşrefoğlu, M; Gül, M; Turan, F1
Fujigaki, Y; Hishida, A; Luo, J; Sun, Y; Tsuji, T; Yasuda, H1
Druse, MJ; Sheth, DS; Tajuddin, NF1
Lewinski, A; Nowak, D; Pietras, T; Sewerynek, E; Stuss, M; Wiktorska, JA1
Cilio, MR; Ferriero, DM1
Kekec, Z; Ozturk, F; Sever, H; Seydaoglul, G1
Mishra, A; Paul, S; Swarnakar, S1
Barriga, C; Bejarano, I; Espino, J; Paredes, SD; Pariente, JA; Rodríguez, AB1
Aksenov, ND; Filatova, NA; Gamaleĭ, IA; Kirpichnikova, KM; Vakhromova, EA1
Beseler, C; Cavalieri, EL; Rogan, E; Saeed, M; Yang, L; Zahid, M1
Anadón, A; Ares, I; Castellano, V; Martínez, M; Martínez, MA; Martínez-Larrañaga, MR; Ramos, E; Romero, A1
Nikiteas, N; Perrea, D; Tsigris, C; Yiannakopoulou, E1
Aydogan, T; Erdogan, D; Eren, MA; Iraz, M; Koksal, M; Kurcer, Z; Tas, M; Ulas, T1
Hendren, RL1
Ferriero, DM; Juul, SE1
Arroll, MA; Neil, J; Wilder, L1
Andrade, CF; da Rosa, DP; e Silva, MB; Fiori, CZ; Forgiarini, LF; Marroni, NP; Martinez, D1
Amaral, AU; Hickmann, FH; Kleemann, D; Ribeiro, CA; Ritter, L; Sitta, Â; Wajner, M1
Fagundes, M; Fiori, CZ; Kaminski, RS; Marroni, NP; Martinez, D; Martins, EF; Montanari, CC; Rosa, DP1
Avitabile, D; Bizzarri, M; Naito, S; Ranieri, D; Shiota, M; Torrisi, MR; Yokomizo, A1
Chan, JY; Hsu, CN; Lee, CT; Tain, YL1
Adamcova, M; Aziriova, S; Balazova, L; Celec, P; Krajcirovicova, K; Pechanova, O; Repova, K; Simko, F; Tothova, L; Vrankova, S; Zorad, S1
Akbarzadeh, S; Anvaripour, A; Bahtoei, M; Iranpour, D; Movahed, A; Netticadan, T; Ostovar, A; Raj, P; Shafiei, E; Shahryari, H; Tahmasebi, R1
da Rosa, MS; Leipnitz, G; Ribeiro, RT; Seminotti, B; Wajner, M; Wyse, ATS; Zanatta, Â1
Ali, T; Anees, M; da Costa Martins, PA; Duygu, B; Farhan, A; Hamera, S; Jan, MI; Javed, Q; Maryam, S; Murtaza, I; Mushtaq, I; Saba, K; Sultan, A; Tabassum, S1
Cheung, PY; Schmölzer, GM; Solevåg, AL1
Abdellah, F; Abderrahim, NA; Ait Abderrahim, L; Alhazmi, AS; Aljassabi, S; Alomery, AM; Taïbi, K1
Aceti, A; Austin, T; Corvaglia, L; Faldella, G; Martini, S1
Cannon, CL; Chen, Q; Chirra, B; DeBerardinis, RJ; Mullen, AR; Shah, KN; Shah, PN; Southerland, MR1
Aziz, JA; El-Malkey, NF; Ismail, KA; Khalil, SS1
Brandão, JCM; Camargo, CR; Leite, AA; Marinho, M; Oliveira-Junior, IS; Reiter, RJ; Sakae, TM1
Aktas, S; Coskun, G; Irkorucu, O; Polat, S; Sapmaz, E; Sapmaz, T; Sevgin, K; Tekayev, M; Topkaraoglu, S1
Silva, BR; Silva, JRV1
Ahmadi, E; Arezoomandan, R; Gorji, A; Mohammadi, N; Nazari, H; Roshanpajouh, M; Shirian, S1

Reviews

11 review(s) available for melatonin and acetylcysteine

ArticleYear
Role of antioxidants in paraquat toxicity.
    Toxicology, 2002, Oct-30, Volume: 180, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Glutathione; Herbicides; Humans; Iron Chelating Agents; Liposomes; Melatonin; Metallothionein; NADP; Oxidation-Reduction; Paraquat; Rats; Reactive Oxygen Species; Vitamin E

2002
Arsenic and lead induced free radical generation and their reversibility following chelation.
    Cellular and molecular biology (Noisy-le-Grand, France), 2007, Apr-15, Volume: 53, Issue:1

    Topics: Acetylcysteine; Adjuvants, Pharmaceutic; Animals; Antioxidants; Arsenic; Arsenic Poisoning; Ascorbic Acid; Calcium; Chelating Agents; Free Radicals; Humans; Lead; Lead Poisoning; Melatonin; Metals; Micronutrients; Molecular Structure; Succimer; Taurine; Thioctic Acid; Unithiol; Vitamin E

2007
Arsenic induced oxidative stress and the role of antioxidant supplementation during chelation: a review.
    Journal of environmental biology, 2007, Volume: 28, Issue:2 Suppl

    Topics: Acetylcysteine; Animals; Antioxidants; Arsenic Poisoning; Ascorbic Acid; Chelating Agents; Chelation Therapy; Dimercaprol; Drug Therapy, Combination; Environmental Pollutants; Humans; Melatonin; Oxidative Stress; Plant Extracts; Selenium; Succimer; Taurine; Thioctic Acid; Vitamin E; Zinc

2007
Synergistic neuroprotective therapies with hypothermia.
    Seminars in fetal & neonatal medicine, 2010, Volume: 15, Issue:5

    Topics: Acetylcysteine; Anticonvulsants; Body Temperature; Cannabinoids; Combined Modality Therapy; Erythropoietin; Fructose; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Levetiracetam; Melatonin; Neuroprotective Agents; Piracetam; Topiramate; Xenon

2010
Pharmacological modulation of oxidative stress response in minimally invasive surgery: systematic review.
    Surgical laparoscopy, endoscopy & percutaneous techniques, 2012, Volume: 22, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Erythromycin; Humans; Laparoscopy; Melatonin; Mesna; Oxidative Stress; Pentoxifylline; Pneumoperitoneum, Artificial; Rabbits; Rats; Verapamil; Zinc Compounds

2012
Autism: biomedical complementary treatment approaches.
    Child and adolescent psychiatric clinics of North America, 2013, Volume: 22, Issue:3

    Topics: Acetylcysteine; Central Nervous System Depressants; Chelation Therapy; Child; Child Development Disorders, Pervasive; Complementary Therapies; Excitatory Amino Acid Antagonists; Fatty Acids, Omega-3; Humans; Immunoglobulins, Intravenous; Melatonin; Memantine; Micronutrients; Treatment Outcome; Vitamin B 12

2013
Pharmacologic neuroprotective strategies in neonatal brain injury.
    Clinics in perinatology, 2014, Volume: 41, Issue:1

    Topics: Acetylcysteine; Allopurinol; Antioxidants; Ascorbic Acid; Biopterins; Erythropoietin; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Fructose; Humans; Hypoxia-Ischemia, Brain; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Melatonin; Memantine; Neuroprotective Agents; Nitric Oxide Synthase Type III; Resveratrol; Stilbenes; Topiramate; Vitamin E; Xenon

2014
Nutritional interventions for the adjunctive treatment of schizophrenia: a brief review.
    Nutrition journal, 2014, Sep-16, Volume: 13

    Topics: Acetylcysteine; Antipsychotic Agents; Ascorbic Acid; Databases, Factual; Diet, Gluten-Free; Dietary Supplements; Fatty Acids, Unsaturated; Folic Acid; Glutamates; Humans; Melatonin; Oxidative Stress; Randomized Controlled Trials as Topic; Schizophrenia; Thioctic Acid; Vitamin B Complex; Vitamin D; Vitamin E

2014
Novel interventions to reduce oxidative-stress related brain injury in neonatal asphyxia.
    Free radical biology & medicine, 2019, Volume: 142

    Topics: Acetylcysteine; Allopurinol; Argon; Asphyxia Neonatorum; Cannabinoids; Erythropoietin; Female; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Magnesium Sulfate; Melatonin; Neuroprotective Agents; Oxidative Stress; Pregnancy; Treatment Outcome; Xenon

2019
Free radicals and neonatal encephalopathy: mechanisms of injury, biomarkers, and antioxidant treatment perspectives.
    Pediatric research, 2020, Volume: 87, Issue:5

    Topics: Acetylcysteine; Allopurinol; Animals; Antioxidants; Asphyxia Neonatorum; Biomarkers; Brain Injuries; Clinical Trials as Topic; DNA; Erythropoietin; Free Radicals; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Malondialdehyde; Melatonin; Nitric Oxide; Oxidative Stress; Prostaglandins; Proteins; Uric Acid

2020
Mechanisms of action of non-enzymatic antioxidants to control oxidative stress during in vitro follicle growth, oocyte maturation, and embryo development.
    Animal reproduction science, 2023, Volume: 249

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Carnitine; Cysteamine; Embryonic Development; Glutathione; In Vitro Oocyte Maturation Techniques; Lycopene; Melatonin; Oocytes; Oxidative Stress; Phycocyanin; Quercetin; Reactive Oxygen Species; Resveratrol

2023

Trials

1 trial(s) available for melatonin and acetylcysteine

ArticleYear
Effects of N-acetyl cysteine and melatonin on early reperfusion injury in patients undergoing coronary artery bypass grafting: A randomized, open-labeled, placebo-controlled trial.
    Medicine, 2018, Volume: 97, Issue:30

    Topics: Acetylcysteine; Adult; Aged; Antioxidants; Cardiotonic Agents; Coronary Artery Bypass; Coronary Disease; Drug Monitoring; Female; Humans; Male; Melatonin; Middle Aged; Myocardial Reperfusion Injury; Oxidative Stress; Treatment Outcome

2018

Other Studies

58 other study(ies) available for melatonin and acetylcysteine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives.
    Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Calcium; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytotoxins; Electron Transport Chain Complex Proteins; Electrophorus; Glucose; Hippocampus; Humans; Isomerism; Models, Molecular; Naphthyridines; Neuroprotective Agents; Okadaic Acid; Oligomycins; Oxygen; Peptide Fragments; Protein Binding; Protein Phosphatase 2; Rats; Rotenone; Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Synthesis, structure, theoretical and experimental in vitro antioxidant/pharmacological properties of α-aryl, N-alkyl nitrones, as potential agents for the treatment of cerebral ischemia.
    Bioorganic & medicinal chemistry, 2011, Jan-15, Volume: 19, Issue:2

    Topics: Antioxidants; Brain Ischemia; Cell Line, Tumor; Humans; Hydrogen Bonding; Hydroxyl Radical; Models, Theoretical; Nitrogen Oxides; Reactive Oxygen Species; Thermodynamics

2011
Carbamate derivatives of indolines as cholinesterase inhibitors and antioxidants for the treatment of Alzheimer's disease.
    Journal of medicinal chemistry, 2012, Dec-13, Volume: 55, Issue:23

    Topics: Alzheimer Disease; Animals; Antioxidants; Apoptosis; Carbamates; Chickens; Cholinesterase Inhibitors; Humans; Indoles; Neurons

2012
Effect of antioxidant treatments on nitrate tolerance development in normotensive and hypertensive rats.
    Journal of hypertension, 2000, Volume: 18, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Coronary Vessels; Drug Tolerance; Endothelium, Vascular; Hypertension; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Nitrates; Nitroprusside; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serotonin; Vasodilation

2000
Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occuring during 7-ketocholesterol-induced apoptosis.
    Free radical biology & medicine, 2000, Mar-01, Volume: 28, Issue:5

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Cytochrome c Group; Cytosol; Free Radicals; Glutathione; Humans; Intracellular Membranes; Ketocholesterols; Kinetics; Melatonin; Membrane Potentials; Microscopy, Electron; Mitochondria; Superoxides; U937 Cells; Vitamin E

2000
Antioxidant compounds interfere with the 3.
    Cancer detection and prevention, 2000, Volume: 24, Issue:5

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Colorimetry; Coloring Agents; Culture Media; Dithiothreitol; Kinetics; Melatonin; Mercaptoethanol; Oxidation-Reduction; Pyrrolidines; Pyrrolidonecarboxylic Acid; Reagent Kits, Diagnostic; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles; Thiazolidines; Thiocarbamates; Vitamin E

2000
[Induction by ethanol of 'phenomenon of switching estrogen effect' and its correction].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2001, Volume: 87, Issue:4

    Topics: Acetylcysteine; Alcohol Drinking; Animals; Antioxidants; Ascorbic Acid; Carnosine; Cell Division; Comet Assay; DNA Damage; Estradiol; Female; Melatonin; Ovariectomy; Rats; Swimming; Uterus; Vitamin E

2001
Glutamate induces oxidative stress not mediated by glutamate receptors or cystine transporters: protective effect of melatonin and other antioxidants.
    Journal of pineal research, 2001, Volume: 31, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Brain; Carrier Proteins; Cystine; Glutamic Acid; Glutathione; Male; Melatonin; Oxidative Stress; Rats; Rats, Wistar; Receptors, Glutamate

2001
Modification of uterotropic effect of estrogens by whole-body gamma-irradiation.
    Bulletin of experimental biology and medicine, 2001, Volume: 132, Issue:2

    Topics: Acetylcysteine; alpha-Tocopherol; Animals; Ascorbic Acid; Carcinogens; Carnosine; Cell Nucleus; Cholesterol; DNA Damage; Dose-Response Relationship, Radiation; Estradiol; Female; Gamma Rays; Melatonin; Organ Size; Rats; Rats, Inbred Strains; Swimming; Time Factors; Uterus; Whole-Body Irradiation

2001
Photic regulation of melatonin in rat retina and the role of proteasomal proteolysis.
    Neuroreport, 2001, Dec-04, Volume: 12, Issue:17

    Topics: Acetylcysteine; Animals; Arylamine N-Acetyltransferase; Circadian Rhythm; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Down-Regulation; Male; Melatonin; Multienzyme Complexes; Peptide Hydrolases; Photic Stimulation; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Retina; RNA, Messenger

2001
Retinal melatonin production: role of proteasomal proteolysis in circadian and photic control of arylalkylamine N-acetyltransferase.
    Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:2

    Topics: Acetylcysteine; Animals; Arylamine N-Acetyltransferase; Blotting, Western; Chickens; Circadian Rhythm; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Male; Melatonin; Multienzyme Complexes; Photic Stimulation; Pineal Gland; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Rabbits; Retina

2002
Chronic antioxidant treatment improves sympathetic functions and beta-adrenergic pathway in the spontaneously hypertensive rats.
    Journal of hypertension, 2003, Volume: 21, Issue:1

    Topics: Acetylcysteine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Antioxidants; Aorta; Binding Sites; Binding, Competitive; Blood Pressure; Catecholamines; Drug Administration Schedule; Heart Rate; Hypertension; In Vitro Techniques; Isoproterenol; Male; Melatonin; Mesenteric Arteries; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Sympathetic Nervous System

2003
Melatonin and N-acetylcysteine have beneficial effects during hepatic ischemia and reperfusion.
    Life sciences, 2003, May-02, Volume: 72, Issue:24

    Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Female; Free Radical Scavengers; Glutathione; Ischemia; Lipid Peroxidation; Liver; Liver Circulation; Liver Function Tests; Male; Malondialdehyde; Melatonin; Neutrophil Infiltration; Oxidation-Reduction; Peroxidase; Proteins; Rats; Rats, Wistar; Reperfusion Injury

2003
Modification of the uterotropic effect produced by estrogens in aging rats.
    Bulletin of experimental biology and medicine, 2002, Volume: 134, Issue:5

    Topics: Acetylcysteine; Aging; Animals; Ascorbic Acid; Carnosine; DNA Damage; Endometrium; Estradiol; Female; Melatonin; Organ Size; Rats; Receptors, Progesterone; Swimming; Uterus; Vitamin E

2002
Protective effects of melatonin, vitamin E and N-acetylcysteine against acetaminophen toxicity in mice: a comparative study.
    Journal of pineal research, 2003, Volume: 35, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Blood Urea Nitrogen; Creatinine; Kidney; Liver; Melatonin; Mice; Vitamin E

2003
Melatonin protects against mercury(II)-induced oxidative tissue damage in rats.
    Pharmacology & toxicology, 2003, Volume: 93, Issue:6

    Topics: Acetylcysteine; Animals; Brain; Female; Kidney; Lipid Peroxidation; Liver; Male; Malondialdehyde; Melatonin; Mercuric Chloride; Mercury Poisoning; Rats; Rats, Wistar

2003
[Switching off the estrogen effect and approaches to its correction].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2003, Volume: 89, Issue:8

    Topics: Acetylcysteine; Aging; Animals; Antioxidants; Ascorbic Acid; Carnosine; Cell Cycle; DNA Damage; Estradiol; Estrogen Receptor Modulators; Estrogens; Ethanol; Female; Fulvestrant; Gamma Rays; Melatonin; Organ Size; Ovariectomy; Physical Conditioning, Animal; Rats; Smoking; Swimming; Uterus; Vitamin D

2003
Melatonin does not prevent the protection of ischemic preconditioning in vivo despite its antioxidant effect against oxidative stress.
    Free radical biology & medicine, 2004, Aug-15, Volume: 37, Issue:4

    Topics: Acetylcysteine; Aldehydes; Animals; Antioxidants; Free Radicals; Ischemic Preconditioning; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Male; Malondialdehyde; Melatonin; Models, Statistical; Oxidative Stress; Rabbits; Reperfusion Injury; Superoxide Dismutase; Time Factors

2004
Differential effects of vanadium, tungsten and molybdenum on inhibition of glucose formation in renal tubules and hepatocytes of control and diabetic rabbits: beneficial action of melatonin and N-acetylcysteine.
    Molecular and cellular biochemistry, 2004, Volume: 261, Issue:1-2

    Topics: Acetylcysteine; Animals; Creatinine; Diabetes Mellitus, Experimental; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Hepatocytes; Kidney Cortex; Kidney Tubules; Melatonin; Membrane Potentials; Metals, Heavy; Mitochondria; Molybdenum; Rabbits; Tungsten; Urea; Vanadium

2004
Treatment by n-acetylcysteine and melatonin increases cardiac baroreflex and improves antioxidant reserve.
    American journal of hypertension, 2004, Volume: 17, Issue:10

    Topics: Acetylcysteine; Animals; Antioxidants; Baroreflex; Blood Pressure; Catecholamines; Erythrocytes; Glutathione Peroxidase; Heart; Heart Rate; Hypertension; Hypertrophy, Left Ventricular; Male; Melatonin; Organ Size; Oxidoreductases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxide Dismutase

2004
Lead induced oxidative stress and its recovery following co-administration of melatonin or N-acetylcysteine during chelation with succimer in male rats.
    Cellular and molecular biology (Noisy-le-Grand, France), 2004, Volume: 50 Online Pub

    Topics: Acetylcysteine; Animals; Antioxidants; Brain; Brain Chemistry; Chelating Agents; Kidney; Lead; Lead Poisoning; Liver; Male; Melatonin; Oxidative Stress; Rats; Succimer

2004
Radical mediators and mitogen-activated protein kinase signaling in oxygen-dependent radiosensitivity of human tumor cell lines.
    Free radical biology & medicine, 2005, Jul-15, Volume: 39, Issue:2

    Topics: Acetylcysteine; Anthracenes; Antioxidants; Apoptosis; Ascorbic Acid; Butadienes; Cell Line, Tumor; Cell Proliferation; DNA Damage; Enzyme Inhibitors; Fluoresceins; HeLa Cells; Humans; Imidazoles; MAP Kinase Signaling System; Melatonin; Mitochondria; Nitriles; Nitrites; Oxazines; Oxygen; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Radiation Tolerance; Rhodamines; Spectrometry, Fluorescence; Xanthenes

2005
Antioxidative and immunomodulatory role of melatonin, sodium selenite, N-acetyl-L-cysteine and quercetin on human umbilical blood.
    Die Pharmazie, 2005, Volume: 60, Issue:9

    Topics: Acetylcysteine; Antioxidants; Cell Proliferation; Comet Assay; DNA Damage; Fetal Blood; Humans; Hydrogen Peroxide; Immunologic Factors; Indicators and Reagents; K562 Cells; Melatonin; Oxidative Stress; Quercetin; Sodium Selenite

2005
Oxidative stress in Graves' disease patients and antioxidant protection against lymphocytes DNA damage in vitro.
    Die Pharmazie, 2005, Volume: 60, Issue:9

    Topics: Acetylcysteine; Adult; Antioxidants; Ascorbic Acid; Comet Assay; DNA Damage; Female; Graves Disease; Humans; Indicators and Reagents; Lymphocytes; Male; Malondialdehyde; Melatonin; Oxidative Stress; Quercetin; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

2005
Melatonin attenuates diabetes-induced oxidative stress in rabbits.
    Journal of pineal research, 2006, Volume: 40, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Diabetes Mellitus, Experimental; Glutathione; Hydroxyl Radical; Kidney Cortex; Liver; Male; Melatonin; Oxidative Stress; Rabbits

2006
Antioxidative effect of melatonin, ascorbic acid and N-acetylcysteine on caerulein-induced pancreatitis and associated liver injury in rats.
    World journal of gastroenterology, 2006, Jan-14, Volume: 12, Issue:2

    Topics: Acetylcysteine; Acute Disease; Animals; Antioxidants; Ascorbic Acid; Ceruletide; Female; Lipid Peroxidation; Liver; Melatonin; Pancreatitis; Rats; Rats, Wistar; Reactive Oxygen Species

2006
The role of reactive oxygen species in the herbicide acetochlor-induced DNA damage on Bufo raddei tadpole liver.
    Aquatic toxicology (Amsterdam, Netherlands), 2006, Jun-10, Volume: 78, Issue:1

    Topics: Acetylcysteine; Animals; Bufonidae; DNA; DNA Damage; Dose-Response Relationship, Drug; Free Radical Scavengers; Herbicides; Larva; Liver; Melatonin; Random Allocation; Reactive Oxygen Species; Statistics as Topic; Toluidines; Water Pollutants, Chemical

2006
The effect of N-acetylcysteine and melatonin in adult spontaneously hypertensive rats with established hypertension.
    European journal of pharmacology, 2007, Apr-30, Volume: 561, Issue:1-3

    Topics: Acetylcysteine; Alkadienes; Animals; Antioxidants; Blood Pressure; Blotting, Western; Free Radical Scavengers; Hypertension; Male; Melatonin; Myography; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Vasoconstriction

2007
Protective effects of melatonin and N-acetylcysteine on hepatic injury in a rat cardiopulmonary bypass model.
    The Journal of surgical research, 2007, Volume: 142, Issue:1

    Topics: Acetylcysteine; Animals; Apoptosis; Cardiopulmonary Bypass; Disease Models, Animal; Free Radical Scavengers; Glutathione; Liver; Male; Malondialdehyde; Melatonin; Nitric Oxide Synthase; Oxidative Stress; Peroxidase; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha

2007
The influence of melatonin and N-acetylcysteine in delta-aminolevulinic acid and lead induced genotoxicity in lymphocytes in vitro.
    Biological trace element research, 2007,Summer, Volume: 117, Issue:1-3

    Topics: Acetylcysteine; Aminolevulinic Acid; Cell Death; Female; Free Radical Scavengers; Humans; Lead; Lymphocytes; Melatonin; Middle Aged; Sister Chromatid Exchange

2007
Comparative effects of several therapatic agents on hepatic damage induced by acute experimental pancreatitis.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:5

    Topics: Acetylcysteine; Acute Disease; Animals; Antioxidants; Arginine; Ascorbic Acid; Ceruletide; Female; Liver Diseases; Melatonin; Pancreatitis; Pentoxifylline; Rats; Rats, Wistar; Statistics, Nonparametric

2008
The molecular mechanisms of the attenuation of cisplatin-induced acute renal failure by N-acetylcysteine in rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:7

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antineoplastic Agents; Antioxidants; Cisplatin; Cross-Linking Reagents; Disease Models, Animal; Free Radical Scavengers; Male; Melatonin; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proline; Rats; Rats, Sprague-Dawley; Thiocarbamates; Tumor Necrosis Factor-alpha

2008
Antioxidant neuroprotection against ethanol-induced apoptosis in HN2-5 cells.
    Brain research, 2009, Aug-18, Volume: 1285

    Topics: Acetylcysteine; Alcohol-Induced Disorders, Nervous System; Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Central Nervous System Depressants; Cytoprotection; Ethanol; Female; Gene Expression Regulation; Hippocampus; Melatonin; Mice; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Reactive Oxygen Species

2009
Effects of certain antioxidants on lipid peroxidation process in lung homogenates of L thyroxine-receiving rats.
    Neuro endocrinology letters, 2010, Volume: 31, Issue:1

    Topics: Acetylcysteine; Ambroxol; Animals; Antioxidants; Antithyroid Agents; Drug Evaluation, Preclinical; Free Radical Scavengers; Injections, Intraperitoneal; Lipid Peroxidation; Lung; Male; Malondialdehyde; Melatonin; Propylthiouracil; Rats; Rats, Wistar; Schiff Bases; Thyroxine; Tissue Extracts; Triiodothyronine

2010
The effect of antioxidants (N-acetylcysteine and melatonin) on hypoxia due to carbonmonoxide poisoning.
    Bratislavske lekarske listy, 2010, Volume: 111, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Brain; Carbon Monoxide Poisoning; Female; Hypoxia; Lung; Melatonin; Rats; Rats, Wistar

2010
Downregulation of matrix metalloproteinase-9 by melatonin during prevention of alcohol-induced liver injury in mice.
    Biochimie, 2011, Volume: 93, Issue:5

    Topics: Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cytokines; Dimethyl Sulfoxide; Down-Regulation; Ethanol; Female; I-kappa B Proteins; Liver; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Melatonin; Mice; Mice, Inbred BALB C; Neutrophil Infiltration; NF-kappa B; Peroxidase

2011
Protective effect of melatonin against human leukocyte apoptosis induced by intracellular calcium overload: relation with its antioxidant actions.
    Journal of pineal research, 2011, Volume: 51, Issue:2

    Topics: Acetylcysteine; Adult; Apoptosis; Calcium; Chelating Agents; DNA Fragmentation; Egtazic Acid; Enzyme Inhibitors; Female; Free Radical Scavengers; Humans; Leukocytes; Male; Melatonin; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Reactive Oxygen Species; Ruthenium Compounds; Thapsigargin

2011
[Decrease in tumorigenic activity of murine hepatoma cells after treatment with antioxidants and melatonin].
    Tsitologiia, 2011, Volume: 53, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Carcinoma, Hepatocellular; Cell Cycle; Flow Cytometry; Humans; Injections, Subcutaneous; Liver Neoplasms; Melatonin; Mice; Mice, Inbred C3H; Thioctic Acid; Transplantation, Isogeneic; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2011
Formation of dopamine quinone-DNA adducts and their potential role in the etiology of Parkinson's disease.
    IUBMB life, 2011, Volume: 63, Issue:12

    Topics: Acetylcysteine; Antioxidants; Benzoquinones; DNA Adducts; Dopamine; Humans; Hydrogen-Ion Concentration; Kinetics; Melatonin; Monophenol Monooxygenase; Parkinson Disease; Resveratrol; Stilbenes; Thioctic Acid

2011
Cytotoxicity induced by deltamethrin and its metabolites in SH-SY5Y cells can be differentially prevented by selected antioxidants.
    Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:6

    Topics: Acetylcysteine; Antioxidants; Benzoates; Cell Line, Tumor; Cell Survival; Chromans; Humans; Insecticides; Lipid Peroxidation; Melatonin; Neutral Red; Nitriles; Nitrites; Pyrethrins

2012
Effect of melatonin and n-acetylcysteine on hepatic injury in rat induced by methanol intoxication: a comparative study.
    European review for medical and pharmacological sciences, 2012, Volume: 16, Issue:4

    Topics: Acetylcysteine; Animals; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Liver; Male; Melatonin; Methanol; Microscopy, Electron; Protective Agents; Rats; Rats, Wistar; Time Factors

2012
Antioxidants inhibit the inflammatory and apoptotic processes in an intermittent hypoxia model of sleep apnea.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2015, Volume: 64, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Caspases; Disease Models, Animal; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Liver; Male; Melatonin; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Sleep Apnea Syndromes; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2015
Disturbance of energy and redox homeostasis and reduction of Na+,K+-ATPase activity provoked by in vivo intracerebral administration of ethylmalonic acid to young rats.
    Biochimica et biophysica acta, 2015, Volume: 1852, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Carbon Dioxide; Corpus Striatum; Electron Transport Complex II; Electron Transport Complex III; Energy Metabolism; Glucose; Glutathione; Homeostasis; Injections, Intraventricular; Lactates; Male; Malonates; Malondialdehyde; Melatonin; Oxidation-Reduction; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Synapses

2015
Melatonin prevents hyperglycemia in a model of sleep apnea.
    Archives of endocrinology and metabolism, 2015, Volume: 59, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; Body Weight; Cholesterol; Disease Models, Animal; Free Radical Scavengers; Hyperglycemia; Hypoxia; Melatonin; Mice, Inbred BALB C; Sleep Apnea, Obstructive; Time Factors; Triglycerides

2015
Nuclear redox imbalance affects circadian oscillation in HaCaT keratinocytes.
    The international journal of biochemistry & cell biology, 2015, Volume: 65

    Topics: Acetylcysteine; ARNTL Transcription Factors; Cell Line; Cell Nucleus; Circadian Rhythm; Gene Expression; Humans; Keratinocytes; Melatonin; Niacinamide; Oxidation-Reduction; Peroxiredoxins; Protein Biosynthesis; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Transcription, Genetic

2015
Maternal melatonin or N-acetylcysteine therapy regulates hydrogen sulfide-generating pathway and renal transcriptome to prevent prenatal N
    American journal of obstetrics and gynecology, 2016, Volume: 215, Issue:5

    Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Biomarkers; Female; Fetal Development; Hydrogen Sulfide; Hypertension; Kidney; Male; Melatonin; NG-Nitroarginine Methyl Ester; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Transcriptome

2016
Lactacystin-Induced Model of Hypertension in Rats: Effects of Melatonin and Captopril.
    International journal of molecular sciences, 2017, Jul-25, Volume: 18, Issue:8

    Topics: Acetylcysteine; Animals; Antihypertensive Agents; Captopril; Disease Models, Animal; Fibrosis; Heart Ventricles; Hypertension; Light; Male; Melatonin; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Ventricular Remodeling

2017
Disruption of Brain Redox Homeostasis, Microglia Activation and Neuronal Damage Induced by Intracerebroventricular Administration of S-Adenosylmethionine to Developing Rats.
    Molecular neurobiology, 2019, Volume: 56, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Brain; Calcium-Binding Proteins; Glutathione Disulfide; Heme Oxygenase-1; Homeostasis; Injections, Intraventricular; Lipids; Malondialdehyde; Melatonin; Microfilament Proteins; Microglia; Neurons; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Rats, Wistar; Reactive Nitrogen Species; Reactive Oxygen Species; S-Adenosylmethionine; Synaptophysin; tau Proteins

2019
Interplay of N acetyl cysteine and melatonin in regulating oxidative stress-induced cardiac hypertrophic factors and microRNAs.
    Archives of biochemistry and biophysics, 2019, Volume: 661

    Topics: Acetylcysteine; Animals; Cardiomegaly; Cell Line; Disease Models, Animal; Free Radical Scavengers; Gene Expression Regulation; Melatonin; MicroRNAs; Oxidative Stress; Rats; Rats, Sprague-Dawley

2019
Protective effects of melatonin and N-acetyl cysteine against oxidative stress induced by microcystin-LR on cardiac muscle tissue.
    Toxicon : official journal of the International Society on Toxinology, 2019, Volume: 169

    Topics: Acetylcysteine; Animals; Antioxidants; Heart; Male; Marine Toxins; Melatonin; Mice; Mice, Inbred BALB C; Microcystins; Microcystis; Myocardium; Oxidative Stress; Protective Agents; Toxicity Tests

2019
N-Acetyl cysteine abrogates silver-induced reactive oxygen species in human cells without altering silver-based antimicrobial activity.
    Toxicology letters, 2020, Oct-10, Volume: 332

    Topics: Acetates; Acetylcysteine; Adenosine Triphosphate; Anti-Bacterial Agents; Ascorbic Acid; Cell Line; Free Radical Scavengers; Gas Chromatography-Mass Spectrometry; Glutathione; Humans; Melatonin; Microbial Sensitivity Tests; Reactive Oxygen Species; Silver; Silver Compounds; Superoxides

2020
Comparative protective effects of
    Canadian journal of physiology and pharmacology, 2021, Volume: 99, Issue:7

    Topics: Acetylcysteine; Animals; Epididymis; Male; Melatonin; Oxidative Stress; Rats; Testis

2021
Melatonin can be, more effective than N-acetylcysteine, protecting acute lung injury induced by intestinal ischemia-reperfusion in rat model.
    Clinics (Sao Paulo, Brazil), 2021, Volume: 76

    Topics: Acetylcysteine; Acute Lung Injury; Animals; Ischemia; Melatonin; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury

2021
Comparison of melatonin, oxytetracycline, and N-acetylcysteine pre-treatments in autologous intraperitoneal ovarian transplantation in rats.
    Biochemical and biophysical research communications, 2022, 05-28, Volume: 606

    Topics: Acetylcysteine; Animals; bcl-2-Associated X Protein; Female; Melatonin; Ovary; Oxytetracycline; Rats; Rats, Wistar

2022
The potential protective effect of melatonin and N-acetylcysteine alone and in combination on opioid-induced testicular dysfunction and degeneration in rat.
    Reproductive toxicology (Elmsford, N.Y.), 2023, Volume: 120

    Topics: Acetylcysteine; Analgesics, Opioid; Animals; Antioxidants; Gonadal Steroid Hormones; Male; Melatonin; Morphine Derivatives; Oxidative Stress; Rats; Rats, Wistar; Semen; Testicular Diseases; Testis

2023