Compounds > melatonin

melatonin and 2-phenylmelatonin

melatonin has been researched along with 2-phenylmelatonin in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (46.15)18.2507
2000's5 (38.46)29.6817
2010's1 (7.69)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Garratt, PJ; Jones, R; Sugden, D; Tocher, DA1
Biella, G; Duranti, A; Fraschini, F; Lucini, V; Salvatori, A; Spadoni, G; Stankov, B1
Balsamini, C; Di Giacomo, B; Diamantini, G; Fraschini, F; Lucini, V; Mor, M; Nonno, R; Pannacci, M; Plazzi, PV; Rivara, S; Spadoni, G; Stankov, BM; Tarzia, G1
Di Giacomo, B; Diamantini, G; Esposti, D; Fraschini, F; Lucini, V; Nonno, R; Pannacci, M; Spadoni, G; Stankov, BM; Tarzia, G1
Balsamini, C; Bordi, F; Diamantini, G; Fraschini, F; Lucini, V; Mor, M; Nonno, R; Plazzi, PV; Rivara, S; Silva, C; Spadoni, G; Stankov, BM; Tarzia, G1
Bedini, A; Fraschini, F; Lucini, V; Mor, M; Pannacci, M; Plazzi, PV; Rivara, S; Silva, C; Spadoni, G; Tarzia, G; Vacondio, F; Zuliani, V1
Laborda, P; Shi, XC; Wang, SY1
Brough, PA; Chen, JJ; Fiehn-Schulze, B; Firnau, G; Snieckus, V1
Lucchelli, A; Masoero, E; Santagostino-Barbone, MG; Spelta, V1
Berger, E; Fauteck, JD; Musshoff, U; Riewenherm, D; Speckmann, EJ1
Alonso-Bedate, M; Alonso-Gómez, AL; Delgado, MJ; Guijarro, A; Isorna, E1
Ajjimaporn, A; Ebadi, M; Govitrapong, P; Ho, B; Klongpanichapak, S; Sawlom, S; Shavali, S1
Batyuk, A; Cherezov, V; Gati, C; Grandner, JM; Han, GW; Hao, S; Huang, XP; Johansson, LC; Katritch, V; Li, C; Liu, W; McCorvy, JD; Olsen, RHJ; Patel, N; Roth, BL; Slocum, ST; Stauch, B; Stevens, RC; Tribo, AR; Weierstall, U; Yous, S; Zaare, S; Zatsepin, NA; Zhu, L1

Reviews

1 review(s) available for melatonin and 2-phenylmelatonin

ArticleYear
Indole-based melatonin analogues: Synthetic approaches and biological activity.
    European journal of medicinal chemistry, 2020, Jan-01, Volume: 185

    Topics: Animals; Dose-Response Relationship, Drug; Humans; Indoles; Ligands; Melatonin; Molecular Structure; Receptors, Melatonin; Structure-Activity Relationship

2020

Other Studies

12 other study(ies) available for melatonin and 2-phenylmelatonin

ArticleYear
Mapping the melatonin receptor. 3. Design and synthesis of melatonin agonists and antagonists derived from 2-phenyltryptamines.
    Journal of medicinal chemistry, 1995, Mar-31, Volume: 38, Issue:7

    Topics: Animals; Binding Sites; Chickens; Drug Design; Ligands; Melanophores; Melatonin; Molecular Structure; Radioligand Assay; Receptors, Cell Surface; Receptors, Melatonin; Structure-Activity Relationship; Tryptamines; Xenopus laevis

1995
2-Substituted 5-methoxy-N-acyltryptamines: synthesis, binding affinity for the melatonin receptor, and evaluation of the biological activity.
    Journal of medicinal chemistry, 1993, Dec-10, Volume: 36, Issue:25

    Topics: Animals; Binding Sites; Cricetinae; Male; Mesocricetus; Quail; Rabbits; Receptors, Cell Surface; Receptors, Melatonin; Structure-Activity Relationship; Tryptamines

1993
Conformationally restrained melatonin analogues: synthesis, binding affinity for the melatonin receptor, evaluation of the biological activity, and molecular modeling study.
    Journal of medicinal chemistry, 1997, Jun-20, Volume: 40, Issue:13

    Topics: Animals; Binding, Competitive; Chickens; Colforsin; Cyclic AMP; Drug Design; Guanosine 5'-O-(3-Thiotriphosphate); Melatonin; Models, Molecular; Quail; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Superior Colliculi

1997
1-(2-Alkanamidoethyl)-6-methoxyindole derivatives: a new class of potent indole melatonin analogues.
    Journal of medicinal chemistry, 1997, Jun-20, Volume: 40, Issue:13

    Topics: Animals; Binding Sites; Binding, Competitive; Chickens; Colforsin; Cyclic AMP; Drug Design; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Melatonin; Models, Chemical; Quail; Superior Colliculi

1997
Melatonin receptor ligands: synthesis of new melatonin derivatives and comprehensive comparative molecular field analysis (CoMFA) study.
    Journal of medicinal chemistry, 1998, Sep-24, Volume: 41, Issue:20

    Topics: Animals; Ligands; Melatonin; Models, Molecular; Molecular Conformation; Quail; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Structure-Activity Relationship; Superior Colliculi

1998
Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation.
    Journal of medicinal chemistry, 2003, Apr-10, Volume: 46, Issue:8

    Topics: Ligands; Melatonin; Models, Molecular; Models, Statistical; Pyrroles; Quantitative Structure-Activity Relationship; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin

2003
Synthesis of 2-iodo- and 2-phenyl-[11C]melatonin: potential PET tracers for melatonin binding sites.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 1998, Volume: 49, Issue:12

    Topics: Acetylation; Binding Sites; Carbon Radioisotopes; Humans; Indicators and Reagents; Mass Spectrometry; Melatonin; Nuclear Magnetic Resonance, Biomolecular; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Tomography, Emission-Computed

1998
2-Phenylmelatonin: a partial agonist at enteric melatonin receptors.
    Pharmacology & toxicology, 2000, Volume: 87, Issue:4

    Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Colon; Dose-Response Relationship, Drug; Free Radical Scavengers; Guinea Pigs; Male; Melatonin; Muscle Contraction; Muscle, Smooth; Prazosin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Serotonin

2000
Melatonin receptors in rat hippocampus: molecular and functional investigations.
    Hippocampus, 2002, Volume: 12, Issue:2

    Topics: Animals; Circadian Rhythm; Electrophysiology; Hippocampus; Male; Melatonin; Membrane Potentials; Oocytes; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrahydronaphthalenes; Tryptamines; Xenopus

2002
Characterization of melatonin binding sites in the brain and retina of the frog Rana perezi.
    General and comparative endocrinology, 2004, Volume: 135, Issue:3

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Diencephalon; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Membranes; Kinetics; Magnesium; Melatonin; Pertussis Toxin; Radioligand Assay; Ranidae; Receptors, Melatonin; Retina; Sodium; Subcellular Fractions; Superior Colliculi; Telencephalon; Tetrahydronaphthalenes; Tryptamines

2004
Melatonin exerts its analgesic actions not by binding to opioid receptor subtypes but by increasing the release of beta-endorphin an endogenous opioid.
    Brain research bulletin, 2005, Jan-30, Volume: 64, Issue:6

    Topics: Analgesics; Analgesics, Opioid; Animals; beta-Endorphin; Binding, Competitive; Brain; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enzyme-Linked Immunosorbent Assay; Melatonin; Mice; Naloxone; Nociceptin; Opioid Peptides; Pineal Gland; Radioligand Assay; Rats; Receptors, Opioid; Subcellular Fractions; Time Factors; Tritium

2005
XFEL structures of the human MT
    Nature, 2019, Volume: 569, Issue:7755

    Topics: Crystallization; Diabetes Mellitus, Type 2; Electrons; Humans; Indenes; Lasers; Ligands; Melatonin; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Structure-Activity Relationship; Substrate Specificity

2019