melatonin has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 8 (42.11) | 29.6817 |
| 2010's | 6 (31.58) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Acuña-Castroviejo, D; Camacho, ME; Carrión, MD; Entrena, A; Escames, G; Espinosa, A; Gallo, MA; López Cara, LC; Tapias, V | 1 |
| Larsson, BS; Lindquist, NG; Lydén-Sokolowski, A | 1 |
| Acuña-Castroviejo, D; Coto-Montes, A; Gaia Monti, M; Ortiz, GG; Reiter, RJ | 1 |
| Chao, CC; Chen, KY; Lee, EH; Ma, YL; Tang, YP | 1 |
| Armstrong, SM; Willis, GL | 1 |
| Ali, SF; Black, MD; Itzhak, Y; Martin, JL | 1 |
| Acuña-Castroviejo, D; Crespo-López, ME; García, JJ; Morán-Moguel, C; Ortiz, GG; Reiter, RJ | 1 |
| Morgan, WW; Nelson, JF | 1 |
| Barcia, C; Barreiro, AF; Bautista, V; Fernández-Villalba, E; Herrero, MT; Navarro-Ruis, JM; Poza Y Poza, M; Sánchez-Bahillo, A | 1 |
| Mohanakumar, KP; Thomas, B | 1 |
| Chen, LJ; Gao, YQ; Li, XJ; Shen, DH; Sun, FY | 1 |
| Ma, J; Mitrofanis, J; Shaw, VE | 1 |
| Borah, A; Mohanakumar, KP | 1 |
| Nath, C; Niranjan, R; Shukla, R | 1 |
| Gómez-Rodríguez, VM; González-Renovato, ED; Ortiz, GG; Pacheco-Moisés, FP; Ramírez-Anguiano, AC; Torres-Sánchez, ED | 1 |
| Dutta, D; Mohanakumar, KP; Naskar, A; Prabhakar, V; Singh, R | 1 |
| Feng, YM; Hu, XT; Lei, XG; Li, GD; Li, H; Li, JL; Luo, R; Lv, L; Ma, L; Su, LY; Xu, L; Yao, YG; Zhou, HJ | 1 |
| Acuña-Castroviejo, D; Aranda, P; Barriocanal-Casado, E; Díaz-Casado, ME; Doerrier, C; Escames, G; Fernández-Gil, B; Fernández-Ortiz, M; López, A; López, LC; Ortiz, F; Venegas, C | 1 |
| Acuña-Castroviejo, D; Aranda, P; Díaz-Casado, ME; Escames, G; Fernández-Gil, BI; Fernández-Ortiz, M; Hidalgo-Gutiérrez, A; López, LC; Rusanova, I; Sayed, RKA | 1 |
19 other study(ies) available for melatonin and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
| Article | Year |
|---|---|
Phenylpyrrole derivatives as neural and inducible nitric oxide synthase (nNOS and iNOS) inhibitors.
Topics: Animals; Binding Sites; Cytosol; Drug Design; Enzyme Inhibitors; Mice; Mitochondria; Models, Molecular; Molecular Structure; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pyrazoles; Stereoisomerism; Structure-Activity Relationship | 2009 |
Accumulation of a parkinsonism-inducing neurotoxin in melanin-bearing neurons: autoradiographic studies on 3H-MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Melatonin; Neurons; Neurotoxins; Parkinson Disease; Pyridines; Rana temporaria | 1986 |
Melatonin is protective against MPTP-induced striatal and hippocampal lesions.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Hippocampus; Immunohistochemistry; Lipid Peroxidation; Melatonin; Mice; MPTP Poisoning | 1997 |
Enhanced glial cell line-derived neurotrophic factor mRNA expression upon (-)-deprenyl and melatonin treatments.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Cell Line; Dopamine; G(M1) Ganglioside; Glial Cell Line-Derived Neurotrophic Factor; Glutathione Peroxidase; Lipid Peroxidation; Male; Melatonin; Monoamine Oxidase; Neostriatum; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selegiline; Superoxide Dismutase | 1998 |
A therapeutic role for melatonin antagonism in experimental models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biological Availability; Body Weight; Circadian Rhythm; Disease Models, Animal; Dyskinesia, Drug-Induced; Free Radical Scavengers; Male; Melatonin; Motor Activity; Oxidopamine; Parkinson Disease; Photoperiod; Phototherapy; Pineal Gland; Rats; Rats, Sprague-Dawley | 1999 |
Neuroprotective role of melatonin in methamphetamine- and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dopamine; Dopamine Agents; Drug Evaluation, Preclinical; Fever; Free Radical Scavengers; Melatonin; Methamphetamine; Mice; Neuroprotective Agents | 1999 |
Protective role of melatonin against MPTP-induced mouse brain cell DNA fragmentation and apoptosis in vivo.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apoptosis; Brain; Cell Count; Corpus Striatum; DNA Fragmentation; Dopamine Agents; Male; Melatonin; Mesencephalon; Mice; Neurons; Time Factors; Tyrosine 3-Monooxygenase | 2001 |
Chronic administration of pharmacological levels of melatonin does not ameliorate the MPTP-induced degeneration of the nigrostriatal pathway.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Free Radical Scavengers; Male; Melatonin; Mice; Mice, Inbred C57BL; Neostriatum; Neural Pathways; Neurons; Neuroprotective Agents; Parkinsonian Disorders; Substantia Nigra; Tyrosine 3-Monooxygenase | 2001 |
Circadian determinations of cortisol, prolactin and melatonin in chronic methyl-phenyl-tetrahydropyridine-treated monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Count; Circadian Rhythm; Disease Models, Animal; Dopamine Agents; Hydrocortisone; Hypothalamus; Macaca fascicularis; Male; Melatonin; Motor Activity; MPTP Poisoning; Prolactin; Substantia Nigra; Tyrosine 3-Monooxygenase | 2003 |
Melatonin protects against oxidative stress caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the mouse nigrostriatum.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Cell-Free System; Dopamine Agents; Dose-Response Relationship, Drug; Free Radical Scavengers; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; Iron; Melatonin; Mice; Mice, Inbred BALB C; Mitochondria; Oxidative Stress; Substantia Nigra; Superoxide Dismutase | 2004 |
Melatonin protects against MPTP/MPP+ -induced mitochondrial DNA oxidative damage in vivo and in vitro.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adjuvants, Immunologic; Animals; Brain; Brain Chemistry; Cell Death; DNA Damage; DNA, Mitochondrial; Dopamine Agents; Herbicides; Male; Melatonin; Mice; MPTP Poisoning | 2005 |
Does melatonin help save dopaminergic cells in MPTP-treated mice?
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antioxidants; Brain; Cell Count; Cell Death; Cell Size; Dopamine; Drug Interactions; Male; Melatonin; Mice; Mice, Inbred BALB C; Neurons; Neurotoxins; Tyrosine 3-Monooxygenase | 2009 |
Melatonin inhibits 6-hydroxydopamine production in the brain to protect against experimental parkinsonism in rodents.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Ascorbic Acid; Brain; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Ferrous Compounds; Levodopa; Male; Melatonin; Mice; Mice, Inbred BALB C; Oxidopamine; Parkinsonian Disorders | 2009 |
The mechanism of action of MPTP-induced neuroinflammation and its modulation by melatonin in rat astrocytoma cells, C6.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Astrocytes; Astrocytoma; Blotting, Western; Cell Line, Tumor; Cell Survival; Gene Expression; Immunohistochemistry; Inflammation; Melatonin; Neurotoxins; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Rats; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Fish oil, melatonin and vitamin E attenuates midbrain cyclooxygenase-2 activity and oxidative stress after the administration of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cyclooxygenase 2; Fish Oils; Lipid Peroxidation; Melatonin; Mesencephalon; Mice; Mice, Inbred C57BL; Oxidative Stress; Vitamin E | 2013 |
Melatonin enhances L-DOPA therapeutic effects, helps to reduce its dose, and protects dopaminergic neurons in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Dopaminergic Neurons; Drug Synergism; Levodopa; Male; Melatonin; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Parkinsonian Disorders; Substantia Nigra | 2015 |
Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; Autophagy; Cyclin-Dependent Kinase 5; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Haplorhini; Melatonin; Mice; Neurotoxins; Parkinson Disease | 2015 |
Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Gene Expression Regulation; Male; Melatonin; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Oxygen Consumption; Parkinson Disease, Secondary; Substantia Nigra | 2017 |
In Vivo Determination of Mitochondrial Respiration in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Zebrafish Reveals the Efficacy of Melatonin in Restoring Mitochondrial Normalcy.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Embryo, Nonmammalian; Energy Metabolism; Melatonin; Mitochondria; MPTP Poisoning; Neurotoxins; Oxidative Stress; Protective Agents; Zebrafish | 2018 |