melatonin has been researched along with 1-methyl-3-isobutylxanthine in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (18.75) | 18.7374 |
| 1990's | 15 (46.88) | 18.2507 |
| 2000's | 8 (25.00) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Calvo, JR; Guerrero, JM; Lopez-Gonzalez, MA; Osuna, C; Rubio, A | 1 |
| Hashemi, F; Niles, LP | 1 |
| Blazynski, C; Cohen, AI; Ferrendelli, JA | 1 |
| Besharse, JC; Iuvone, PM | 1 |
| Guerrero, JM; Reiter, RJ; Santana, C; Troiani, ME | 1 |
| Barker, D; Harrington, J; Pierce, ME; Takahashi, JS | 1 |
| Pratt, BL; Takahashi, JS | 1 |
| Nikaido, SS; Takahashi, JS | 1 |
| Gan, J; Iuvone, PM | 2 |
| Alonso-Gómez, AL; Iuvone, PM | 1 |
| Alonso-Gómez, AL; Avendano, G; Gan, J; Iuvone, PM; Johnson, B | 1 |
| Gonzalez-Brito, A; Hastings, MH; Hazlerigg, DG; Lawson, W; Morgan, PJ | 1 |
| Klein, DC; Vanecek, J | 1 |
| Hill, HZ; Li, W | 1 |
| Lamosová, D; Macková, M; Zeman, M | 1 |
| Abdallah, G; Claude, G; Monia, ZA; Sarda, N | 1 |
| Vanecek, J | 1 |
| Cahill, GM; Hasegawa, M | 1 |
| Faillace, MP; Jaliffa, CO; Keller Sarmiento, MI; Lacoste, FF; Llomovatte, DW; Rosenstein, RE | 1 |
| Meissl, H; Schmid, HA; Zipfel, B | 1 |
| Korf, HW; Kroeber, S; Maronde, E; Meissl, H | 1 |
| Chankiewitz, E; Csernus, VJ; Mühlbauer, E; Musshoff, U; Peschke, D; Peschke, E | 1 |
| Klein, DC; Korf, HW; Laedtke, E; Olcese, J; Schomerus, C; Weller, JL | 1 |
| Andersson, TP; Sköld, HN; Svensson, SP | 1 |
| Mühlbauer, E; Peschke, E; Stumpf, I | 1 |
| Alarma-Estrany, P; Crooke, A; Mediero, A; Peláez, T; Pintor, J | 1 |
| Bazwinsky-Wutschke, I; Mühlbauer, E; Peschke, E; Wolgast, S | 1 |
| Albrecht, E; Bazwinsky-Wutschke, I; Mühlbauer, E; Peschke, E | 1 |
| Albrecht, E; Bazwinsky-Wutschke, I; Mühlbauer, E; Peschke, E; Wolgast, S | 1 |
| Aguiar, FLN; Azevedo, VAN; Barrozo, LG; Batista, ALPS; Costa, FC; Donato, MAM; Lopes, EPF; Nascimento, DR; Paulino, LRFM; Peixoto, CA; Rodrigues, APR; Silva, BR; Silva, JRV | 1 |
32 other study(ies) available for melatonin and 1-methyl-3-isobutylxanthine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Synergistic action of melatonin and vasoactive intestinal peptide in stimulating cyclic AMP production in human lymphocytes.
Topics: 1-Methyl-3-isobutylxanthine; Cyclic AMP; Drug Synergism; Humans; Immunity; Lymphocytes; Melatonin; Phosphodiesterase Inhibitors; Vasoactive Intestinal Peptide | 1992 |
Picomolar-affinity binding and inhibition of adenylate cyclase activity by melatonin in Syrian hamster hypothalamus.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Animals; Binding Sites; Colforsin; Cricetinae; Hypothalamus; Iodine Radioisotopes; Male; Melatonin; Mesocricetus; Radioligand Assay; Receptors, Melatonin; Receptors, Neurotransmitter | 1990 |
Indoleamine-sensitive adenylate cyclase in rabbit retina: characterization and distribution.
Topics: 1-Methyl-3-isobutylxanthine; 5-Methoxytryptamine; Adenylyl Cyclases; Animals; Cats; Cyclic AMP; Cyclic GMP; Guanosine Triphosphate; Haloperidol; Humans; Melatonin; Methoxydimethyltryptamines; Rabbits; Retina; Serotonin; Serotonin Antagonists; Tryptamines | 1985 |
Cyclic AMP stimulates serotonin N-acetyltransferase activity in Xenopus retina in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Acetyltransferases; Adenosine; Animals; Arylamine N-Acetyltransferase; Bucladesine; Calcium; Circadian Rhythm; Colforsin; Cyclic AMP; Darkness; Fishes; Guinea Pigs; In Vitro Techniques; Light; Melatonin; Retina; Tyrosine 3-Monooxygenase; Xenopus laevis | 1986 |
The in vitro activation of cyclic AMP production by either forskolin or isoproterenol in the Syrian hamster pineal during the day is not accompanied by an increase in melatonin production.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Circadian Rhythm; Colforsin; Cricetinae; Cyclic AMP; Isoproterenol; Kinetics; Male; Melatonin; Mesocricetus; Organ Culture Techniques; Pineal Gland | 1988 |
Cyclic AMP-dependent melatonin production in Y79 human retinoblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 5-Hydroxytryptophan; 8-Bromo Cyclic Adenosine Monophosphate; Colforsin; Cyclic AMP; Humans; Melatonin; Middle Aged; Retinoblastoma; Tumor Cells, Cultured | 1989 |
Vasoactive intestinal polypeptide and alpha 2-adrenoceptor agonists regulate adenosine 3',5'-monophosphate accumulation and melatonin release in chick pineal cell cultures.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Agonists; Amino Acid Sequence; Animals; Brimonidine Tartrate; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Kinetics; Melatonin; Molecular Sequence Data; Pineal Gland; Quinoxalines; Radioimmunoassay; Sequence Homology, Nucleic Acid; Structure-Activity Relationship; Vasoactive Intestinal Peptide | 1989 |
Twenty-four hour oscillation of cAMP in chick pineal cells: role of cAMP in the acute and circadian regulation of melatonin production.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Chickens; Circadian Rhythm; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Male; Melatonin; Pineal Gland | 1989 |
Melatonin receptor-mediated inhibition of cyclic AMP accumulation in chick retinal cell cultures.
Topics: 1-Methyl-3-isobutylxanthine; 5-Methoxytryptamine; Animals; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Iodine Radioisotopes; Melatonin; Neurons; Pertussis Toxin; Photoreceptor Cells; Potassium; Receptors, Cell Surface; Receptors, Melatonin; Retina; Second Messenger Systems; Structure-Activity Relationship; Tryptamines; Virulence Factors, Bordetella | 1994 |
Functional interaction of melatonin receptors and D1 dopamine receptors in cultured chick retinal neurons.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Animals; Benzazepines; Cells, Cultured; Chick Embryo; Cyclic AMP; GTP-Binding Proteins; Haloperidol; Inositol Phosphates; Melatonin; Models, Neurological; Neurons; Pertussis Toxin; Receptors, Cell Surface; Receptors, Dopamine D1; Receptors, Melatonin; Retina; Signal Transduction; Synaptic Transmission; Virulence Factors, Bordetella | 1995 |
Melatonin biosynthesis in cultured chick retinal photoreceptor cells: calcium and cyclic AMP protect serotonin N-acetyltransferase from inactivation in cycloheximide-treated cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arylamine N-Acetyltransferase; Calcium; Cells, Cultured; Chick Embryo; Cyclic AMP; Cycloheximide; Kinetics; Leucine; Melatonin; Photoreceptor Cells; Retina; Tritium | 1995 |
Melatonin biosynthesis in photoreceptor-enriched chick retinal cell cultures: role of cyclic AMP in the K(+)-evoked, Ca(2+)-dependent induction of serotonin N-acetyltransferase activity.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Arylamine N-Acetyltransferase; Calcium; Cells, Cultured; Chick Embryo; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Induction; Ion Channel Gating; Melatonin; Membrane Potentials; Photoreceptor Cells; Potassium | 1995 |
Prolonged exposure to melatonin leads to time-dependent sensitization of adenylate cyclase and down-regulates melatonin receptors in pars tuberalis cells from ovine pituitary.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Aluminum; Aluminum Compounds; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Down-Regulation; Fluorides; Iodine Radioisotopes; Kinetics; Melatonin; Pituitary Gland, Anterior; Receptors, Melatonin; Receptors, Neurotransmitter; Sheep | 1993 |
Mechanism of melatonin signal transduction in the neonatal rat pituitary.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Calcimycin; Calcium; Colforsin; Cyclic AMP; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Melatonin; Nifedipine; Organ Culture Techniques; Pituitary Gland, Anterior; Rats; Receptors, Cell Surface; Receptors, Melatonin; Signal Transduction | 1995 |
Induced melanin reduces mutations and cell killing in mouse melanoma.
Topics: 1-Methyl-3-isobutylxanthine; alpha-MSH; Animals; DNA Damage; Melanoma; Melatonin; Mice; Mutation; Tumor Cells, Cultured | 1997 |
Regulation of rhythmic melatonin production in pineal cells of chick embryo by cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Chick Embryo; Colforsin; Cyclic AMP; Melatonin; Phosphodiesterase Inhibitors; Pineal Gland | 1998 |
Docosahexaenoic acid reduces both cyclic nucleotide and melatonin synthesis in rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cells, Cultured; Cyclic AMP; Cyclic GMP; Docosahexaenoic Acids; Male; Melatonin; Norepinephrine; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Pineal Gland; Rats | 1998 |
Melatonin inhibits release of luteinizing hormone (LH) via decrease of [Ca2+]i and cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Calcium; Calcium Channel Agonists; Cells, Cultured; Cyclic AMP; Drug Synergism; Female; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Melatonin; Pituitary Gland, Anterior; Rats; Rats, Wistar | 1998 |
Modulation of rhythmic melatonin synthesis in Xenopus retinal photoreceptors by cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Circadian Rhythm; Colforsin; Culture Techniques; Cyclic AMP; Enzyme Inhibitors; Male; Melatonin; Photoreceptor Cells, Vertebrate; Retina; Stimulation, Chemical; Thionucleotides; Xenopus laevis | 1999 |
Effect of GABA on melatonin content in golden hamster retina.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bicuculline; Cricetinae; Cyclic AMP; Cyclic GMP; Darkness; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Male; Melatonin; Mesocricetus; Retina | 1999 |
Photoendocrine signal transduction in pineal photoreceptors of the trout. Role of cGMP and nitric oxide.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic GMP; Darkness; Dihydrolipoamide Dehydrogenase; Immunohistochemistry; Light; Melatonin; NADP; Nitric Oxide; Nitric Oxide Synthase; Organ Culture Techniques; Penicillamine; Photoreceptor Cells, Vertebrate; Pineal Gland; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Trout | 1999 |
Analyses of signal transduction cascades reveal an essential role of calcium ions for regulation of melatonin biosynthesis in the light-sensitive pineal organ of the rainbow trout (Oncorhynchus mykiss).
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arylamine N-Acetyltransferase; Calcium; Calcium Signaling; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cysteine Endopeptidases; Female; Gene Expression; Immunohistochemistry; Male; Melatonin; Multienzyme Complexes; Oncorhynchus mykiss; Organ Culture Techniques; Phosphodiesterase Inhibitors; Phosphorylation; Photic Stimulation; Pineal Gland; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Signal Transduction; Transcription, Genetic | 2000 |
Receptor (MT(1)) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Biological Transport; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Melatonin; Pancreatic Neoplasms; Phosphodiesterase Inhibitors; Polymerase Chain Reaction; Probenecid; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Signal Transduction; Tryptamines; Tumor Cells, Cultured | 2002 |
Signal transduction and regulation of melatonin synthesis in bovine pinealocytes: impact of adrenergic, peptidergic and cholinergic stimuli.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arylamine N-Acetyltransferase; Calcium Signaling; Cattle; Cyclic AMP; Immunohistochemistry; Melatonin; Neuropeptides; Norepinephrine; Phenylephrine; Pineal Gland; Pituitary Adenylate Cyclase-Activating Polypeptide; Signal Transduction; Vasoactive Intestinal Peptide | 2002 |
Phosphoinositide 3-kinase is involved in Xenopus and Labrus melanophore aggregation.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Androstadienes; Animals; Chromones; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Kinetics; Melanocyte-Stimulating Hormones; Melanophores; Melanosomes; Melatonin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Norepinephrine; Papaverine; Perciformes; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Diester Hydrolases; Phosphorylation; Rolipram; Signal Transduction; Wortmannin; Xenopus laevis | 2003 |
Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Cell Line, Tumor; Colforsin; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide-Gated Cation Channels; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose; Guanylate Cyclase; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Melatonin; Pineal Gland; Rats; Rats, Wistar; Receptor, Melatonin, MT2; Signal Transduction; Tetrahydronaphthalenes; Tryptamines | 2008 |
Sympathetic nervous system modulates the ocular hypotensive action of MT2-melatonin receptors in normotensive rabbits.
Topics: 1-Methyl-3-isobutylxanthine; Administration, Topical; Adrenergic beta-Agonists; Albuterol; Animals; Aqueous Humor; Colforsin; Dose-Response Relationship, Drug; Intraocular Pressure; Isoindoles; Melatonin; Ocular Hypertension; Okadaic Acid; Rabbits; Receptor, Melatonin, MT2; Sympathectomy, Chemical; Sympathetic Nervous System; Terbutaline | 2008 |
Transcripts of calcium/calmodulin-dependent kinases are changed after forskolin- or IBMX-induced insulin secretion due to melatonin treatment of rat insulinoma beta-cells (INS-1).
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Tumor; Colforsin; Gene Expression Regulation, Developmental; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Islets of Langerhans; Melatonin; Rats; Rats, Wistar | 2009 |
Melatonin influences insulin secretion primarily via MT(1) receptors in rat insulinoma cells (INS-1) and mouse pancreatic islets.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line, Tumor; Cyclic AMP; Histocytochemistry; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Melatonin; Mice; Mice, Knockout; Rats; Receptor, Melatonin, MT1; Statistics, Nonparametric | 2012 |
Phosphorylation of cyclic AMP-response element-binding protein (CREB) is influenced by melatonin treatment in pancreatic rat insulinoma β-cells (INS-1).
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Tumor; Colforsin; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Humans; Insulin-Secreting Cells; Insulinoma; Melatonin; Microscopy, Confocal; Pancreatic Neoplasms; Phosphorylation; Rats; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Signal Transduction; Tetrahydronaphthalenes; Time Factors; Transfection; Tryptamines | 2012 |
Effects of cyclic adenosine monophosphate modulating agents during oocyte pre-maturation and the role of melatonin on in vitro maturation of bovine cumulus-oocyte complexes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Monophosphate; Animals; Cattle; Colforsin; Cumulus Cells; Cyclic AMP; Female; In Vitro Oocyte Maturation Techniques; Melatonin; Natriuretic Peptide, C-Type; Oocytes; RNA, Messenger; Superoxide Dismutase | 2023 |