melarsoprol has been researched along with suramin in 63 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 23 (36.51) | 18.7374 |
1990's | 13 (20.63) | 18.2507 |
2000's | 14 (22.22) | 29.6817 |
2010's | 12 (19.05) | 24.3611 |
2020's | 1 (1.59) | 2.80 |
Authors | Studies |
---|---|
Berger, H; Brun, R; Kaiser, M; Saf, R; Seebacher, W; Weis, R | 1 |
Büchold, C; Gelhaus, C; Gut, J; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Stempka, M | 1 |
Breuning, A; Büchold, C; Degel, B; Gelhaus, C; Gut, J; Heppner, S; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rath, J; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Schulz, F; Stempka, M; Stich, A | 1 |
Brun, R; Fotie, J; Gershkovich, P; He, S; Liu, Q; Patrick, DA; Premalatha, K; Reid, CS; Tidwell, RR; Wang, MZ; Wasan, KM; Wenzler, T; Werbovetz, KA | 1 |
Clayton, C; De Muylder, G; Gerwick, L; Helbig, C; Knudsen, GM; Linington, RG; Mackey, ZB; Mascuch, SM; McKerrow, JH; Sanchez, LM | 1 |
Ariën, KK; Augustyns, K; Cos, P; Dirié, B; Heeres, J; Joossens, J; Lewi, PJ; Lyssens, S; Maes, L; Michiels, J; Van der Veken, P; Vanham, G; Venkatraj, M | 1 |
Ambuehl, C; Breant, L; Christen, P; Cretton, S; Cuendet, M; Ebrahimi, SN; Hamburger, M; Kaiser, M; Karimou, S; Marcourt, L; Perozzo, R; Pourrez, L | 1 |
Brantner, A; Brun, R; Bucar, F; Faist, J; Gröblacher, B; Kaiser, M; Kalia, Y; Merino, V; Perozzo, R; Saf, R; Scapozza, L; Seebacher, W; Weis, R; Wolkinger, V | 1 |
Williamson, J | 1 |
Goodwin, LG; Tierney, ED | 1 |
Brodsky, RE; Gibson, JJ; Schultz, MG; Spencer, HC | 1 |
Foulkes, JR | 1 |
Buyst, H | 1 |
Buyst, H; Jones, IG; Lowenthal, MN | 1 |
Ormerod, WE; Raseroka, BH | 1 |
Bales, JD; Harrison, SM; Mbwabi, DL; Schecter, PJ | 1 |
Thomson, KD | 1 |
Baeriswyl, S; Brun, R; Kunz, C | 1 |
Chumo, DA; Muriithi, RM; Mwangi, J; Reardon, MJ; Towett, S; Wellde, BT | 1 |
Abinya, A; Chumo, DA; Dola, S; Mbwabi, D; Reardon, MJ; Siongok, TA; Smith, DH; Wanyama, L; Wellde, BT | 1 |
Lefrock, JL; Smith, BR | 1 |
Bouteille, B; Darde, ML; Pestre-Alexandre, M | 1 |
Gutteridge, WE | 1 |
Balber, AE; Frommel, TO | 1 |
van der Meer, C; Versluijs-Broers, JA | 1 |
Agbowu, J; Ajayi, N; Weir, AB | 1 |
Wu, SH | 1 |
Dukes, P | 1 |
Barrett-Connor, E | 1 |
Hall, JE; Seed, JR; Shertzer, HG | 1 |
Boa Yapo, F; Doua, F | 1 |
Roberts, JF; Yunmbam, MK | 1 |
Dadzie, S; Kimata, DM; Makawiti, DW; Tengekyon, KM; Waindi, EN | 1 |
Burkardt, H; Damian, MS; Dorndorf, W; Leinweber, B; Schachenmayr, W; Singer, I | 1 |
Brun, R; Lun, ZR | 1 |
Milord, F; Pépin, J | 1 |
Brun, R; Iten, M; Kaminsky, R; Matovu, E | 1 |
Anene, BM; Anika, SM; Chukwu, CC; Ross, CA | 1 |
Scott, AG; Tait, A; Turner, CM | 1 |
Barrett, MP; Bertelli, M; Dallocchio, F; Hanau, S; Rippa, M | 1 |
Bales, JD; Harris, RW; Harrison, SM | 1 |
Lastre González, M; Pérez Martín, O; Shwalbach, J; Urban, M | 1 |
Boken, D; Malesker, MA; Murphy, PJ; Ruma, TA; Smith, PW; Vuchetich, PJ | 1 |
Barrett, MP; Barrett, SV | 1 |
Bouteille, B; Dumas, M | 1 |
Etchegorry, MG; Helenport, JP; Jannin, J; Legros, D; Pecoul, B | 1 |
Bradley, B; Gettinby, G; Jennings, FW; Kennedy, PG; Murray, M; Rodgers, J | 1 |
Kager, PA | 1 |
Nok, AJ | 1 |
Docampo, R; Moreno, SN | 1 |
Kaboya, JS; Kibona, SN; Lubega, GW; Matemba, L | 1 |
Kibiki, GS; Murphy, DK | 1 |
Berbari, EF; Jacobson, KM; Kumar, N; Orenstein, R; Uslan, DZ | 1 |
De Koning, HP; Dogruel, M; Rodgers, J; Sanderson, L; Thomas, SA | 1 |
Blum, J; Brun, R; Burri, C; Chappuis, F | 1 |
Schlitzer, M | 1 |
Alsford, S; Baker, N; Berriman, M; Eckert, S; Field, MC; Glover, L; Horn, D; Leung, KF; Sanchez-Flores, A; Turner, DJ | 1 |
Bailey, R; Brown, M; Easom, N; Watson, J; Wise, E | 1 |
Allan, M; Blum, J; Burri, C; Edielu, A; Haary, EP; Kakembo, A; Kibona, S; Kuepfer, I; Schmid, C | 1 |
Bucheton, B; Courtois, P; Cuny, G; Daulouède, S; Dethoua, M; Nzoumbou-Boko, R; Semballa, S; Truc, P; Vincendeau, P | 1 |
Alsford, S; Baker, N; Dominicus, C; Glover, L; Horn, D; Hutchinson, S; Thomas, JA; Trenaman, A | 1 |
Auma, JE; Chemuliti, JK; Gitonga, PK; Kurgat, RK; Mdachi, RE; Murilla, GA; Ndung'u, K; Ngae, GN; Thuita, JK; Thungu, DK | 1 |
7 review(s) available for melarsoprol and suramin
Article | Year |
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Chemotherapy of African trypanosomiasis.
Topics: Adult; Amidines; Animals; Cattle; Drug Resistance; Drug Therapy, Combination; Humans; Melarsoprol; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1976 |
Existing chemotherapy and its limitations.
Topics: Chagas Disease; Gentian Violet; Humans; Melarsoprol; Nifurtimox; Nitroimidazoles; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African | 1985 |
Drugs for the treatment of parasitic infection.
Topics: Antimony; Bithionol; Chloroquine; Diethylcarbamazine; Humans; Mebendazole; Melarsoprol; Metronidazole; Niclosamide; Niridazole; Oxamniquine; Parasitic Diseases; Pentamidine; Piperazines; Primaquine; Pyrantel Pamoate; Pyrimethamine; Suramin; Thiabendazole; Trichlorfon | 1982 |
The treatment of human African trypanosomiasis.
Topics: Animals; Diminazene; Eflornithine; Humans; Melarsoprol; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 1994 |
Arsenicals (melarsoprol), pentamidine and suramin in the treatment of human African trypanosomiasis.
Topics: Animals; Drug Resistance; HIV; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2003 |
Current chemotherapy of human African trypanosomiasis.
Topics: Animals; Eflornithine; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African | 2003 |
[Agents for the treatment of African sleeping sickness. Those developed in the last century].
Topics: Animals; Eflornithine; History, 20th Century; Humans; Melarsoprol; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African | 2009 |
2 trial(s) available for melarsoprol and suramin
Article | Year |
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Attempt to correlate urine arsenic excretion with clinical course during melarsoprol therapy of patients with Rhodesian trypanosomiasis.
Topics: Adolescent; Adult; Aged; Animals; Arsenic; Child; Child, Preschool; Creatinine; Drug Therapy, Combination; Female; Humans; Male; Melarsoprol; Middle Aged; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 1997 |
Safety and efficacy of the 10-day melarsoprol schedule for the treatment of second stage Rhodesiense sleeping sickness.
Topics: Adolescent; Adult; Aged; Brain Diseases; Child; Drug Administration Schedule; Endemic Diseases; Female; Humans; Male; Melarsoprol; Middle Aged; Suramin; Tanzania; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda | 2012 |
54 other study(ies) available for melarsoprol and suramin
Article | Year |
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Antiprotozoal activities of new bis-chlorophenyl derivatives of bicyclic octanes and aza-nonanes.
Topics: Animals; Antiprotozoal Agents; Bridged Bicyclo Compounds, Heterocyclic; In Vitro Techniques; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Stereoisomerism; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense | 2006 |
On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences.
Topics: Amino Acid Sequence; Animals; Antiprotozoal Agents; Cathepsin L; Cathepsins; Cattle; Combinatorial Chemistry Techniques; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diamide; Drug Evaluation, Preclinical; Fumarates; Humans; Peptide Library; Plasmodium falciparum | 2009 |
Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids.
Topics: Antimalarials; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei | 2010 |
Synthesis and antitrypanosomal evaluation of derivatives of N-benzyl-1,2-dihydroquinolin-6-ols: Effect of core substitutions and salt formation.
Topics: Animals; Cyclization; Mice; Quinolines; Salts; Structure-Activity Relationship; Trypanocidal Agents | 2011 |
Examination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei.
Topics: Animals; Biological Products; Chagas Disease; Glycolysis; Humans; Leishmania donovani; Lipopeptides; Microbodies; Microscopy, Fluorescence; Trypanosoma brucei brucei; Zebrafish | 2013 |
From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds.
Topics: Anti-HIV Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense | 2014 |
Antitrypanosomal quinoline alkaloids from the roots of Waltheria indica.
Topics: Alkaloids; Animals; Inhibitory Concentration 50; Malvaceae; Mice; Molecular Structure; Niger; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Quinolines; Trypanocidal Agents; Trypanosoma | 2014 |
Synthesis of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities.
Topics: Administration, Oral; Animals; Antiprotozoal Agents; Azabicyclo Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Rats; Structure-Activity Relationship; Tissue Distribution; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2015 |
Chemotherapy of sleeping sickness.
Topics: Arsenicals; Humans; Melarsoprol; Pentamidine; Suramin; Trypanosomiasis, African | 1979 |
Trypanocidal activity of blood and tissue fluid from normal and infected rabbits treated with curative drugs.
Topics: Animals; Benzamidines; Body Fluids; Diminazene; Ethidium; Male; Melarsoprol; Mice; Phenanthridines; Rabbits; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis | 1977 |
Imported African trypanosomiasis in the United States.
Topics: Adult; Aged; Diagnosis, Differential; Female; Humans; Male; Melarsoprol; Middle Aged; Suramin; Trypanosomiasis, African; United States | 1975 |
An evaluation of prednisolone as a routine adjunct to the treatment of T. rhodesiense.
Topics: Adult; Arsenicals; Child; Drug Administration Schedule; Drug Evaluation, Preclinical; Humans; Melarsoprol; Meningoencephalitis; Prednisolone; Suramin; Trypanosoma; Trypanosomiasis, African; Zambia | 1975 |
The treatment of T. rhodesiense sleeping sickness, with special reference to its physio-pathological and epidemiological basis.
Topics: Arsenicals; Chloroquine; Humans; Melarsoprol; Proguanil; Suramin; Trypanosomiasis, African; Zambia | 1975 |
Electrocardiographic changes in African trypanosomiasis caused by Trypanosoma brucei rhodesiense.
Topics: Adolescent; Adult; Aged; Electrocardiography; Female; Heart Diseases; Humans; Male; Melarsoprol; Middle Aged; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African | 1975 |
Screening compounds for sleeping sickness therapy without relapse.
Topics: Animals; Bleomycin; Drug Evaluation, Preclinical; Eflornithine; Melarsoprol; Metronidazole; Mice; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1988 |
Treatment of arsenical refractory Rhodesian sleeping sickness in Kenya.
Topics: Adult; Animals; Arsenicals; Drug Therapy, Combination; Eflornithine; Female; Humans; Kenya; Male; Melarsoprol; Middle Aged; Recurrence; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African | 1989 |
Tryparsamide.
Topics: Drug Therapy, Combination; Humans; Melarsoprol; Nigeria; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African | 1989 |
In vitro drug sensitivity of Trypanosoma gambiense isolates.
Topics: Animals; Arsenicals; Cote d'Ivoire; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African | 1989 |
Experimental infection of goats with Trypanosoma brucei ssp. and effects of treatment with suramin and Mel-B.
Topics: Animals; Arsenicals; Brain; Central Nervous System; Central Nervous System Diseases; Goat Diseases; Goats; Male; Melarsoprol; Mice; Spinal Puncture; Suramin; Trypanocidal Agents; Trypanosomiasis, African | 1989 |
Treatment of Rhodesian sleeping sickness in Kenya.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Arsenicals; Child; Drug Resistance; Female; Follow-Up Studies; Humans; Kenya; Male; Melarsoprol; Middle Aged; Prospective Studies; Recurrence; Retrospective Studies; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1989 |
Drugs for protozoan infections.
Topics: Antimalarials; Antimony Sodium Gluconate; Antiprotozoal Agents; Humans; Iodoquinol; Melarsoprol; Metronidazole; Nifurtimox; Pentamidine; Protozoan Infections; Suramin | 1987 |
[Action of drugs tested in an acellular medium and in mice infected with Trypanosoma brucei brucei].
Topics: Acetanilides; Animals; Culture Media; Cyclosporins; Eflornithine; In Vitro Techniques; Melarsoprol; Mice; Mitoguazone; Nitroimidazoles; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1988 |
Flow cytofluorimetric analysis of drug accumulation by multidrug-resistant Trypanosoma brucei brucei and T. b. rhodesiense.
Topics: Acriflavine; Animals; Benzimidazoles; Diminazene; Drug Resistance; Ethidium; Flow Cytometry; Fluorescent Dyes; Humans; Indoles; Melarsoprol; Mice; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei | 1987 |
Trypanosoma brucei and T. vivax: salicylhydroxamic acid and glycerol treatment of acute and chronically infected rats.
Topics: Animals; Brain; Drug Administration Schedule; Drug Therapy, Combination; Female; Glycerol; Melarsoprol; Mice; Muscles; Rats; Rats, Inbred Strains; Salicylamides; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis; Trypanosomiasis, African | 1986 |
Hyperendemic West African trypanosomiasis in a rural hospital setting.
Topics: Brain Diseases; Dexamethasone; Drug Administration Schedule; Drug Therapy, Combination; Hospitals, Rural; Humans; Melarsoprol; Nigeria; Suramin; Trypanosomiasis, African | 1985 |
African human trypanosomiasis in southern Sudan. Report of 77 cases.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Male; Melarsoprol; Middle Aged; Sudan; Suramin; Trypanosomiasis, African | 1985 |
Arsenic and old taxa: subspeciation and drug sensitivity in Trypanosoma brucei.
Topics: Animals; Arsenicals; Diminazene; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Isoenzymes; Male; Melarsoprol; Mice; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1984 |
Hepatic mixed-function oxidase activity in mice infected with Trypanosoma brucei gambiense or treated with trypanocides.
Topics: Animals; Arsenicals; Cytochrome P-450 Enzyme System; Liver; Male; Melarsoprol; Mice; Mixed Function Oxygenases; Oxidoreductases; Pentobarbital; Sleep; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African | 1981 |
[Current therapy of trypanosomiasis].
Topics: Adenosylmethionine Decarboxylase; Animals; Arsenicals; Deoxyadenosines; Drug Resistance; Eflornithine; Enzyme Inhibitors; Hospitalization; Humans; Melarsoprol; Pentamidine; Randomized Controlled Trials as Topic; Recurrence; Suramin; Triazines; Trypanocidal Agents; Trypanosomiasis, African | 1994 |
In vivo evaluation of reuterin and its combinations with suramin, melarsoprol, DL-alpha-difluoromethylornithine and bleomycin in mice infected with Trypanosoma brucei brucei.
Topics: Aldehydes; Animals; Anti-Bacterial Agents; Bleomycin; Drug Therapy, Combination; Eflornithine; Female; Glyceraldehyde; Lethal Dose 50; Melarsoprol; Mice; Propane; Suramin; Trypanosomiasis, African | 1993 |
Delayed recovery of adrenocortical and testicular function after chemotherapy of human trypanosomiasis.
Topics: Adolescent; Adrenal Cortex; Adult; Aged; Anemia; Animals; Hematocrit; Humans; Hydrocortisone; Hypogonadism; Luteinizing Hormone; Male; Melarsoprol; Middle Aged; Suramin; Testis; Testosterone; Time Factors; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 1994 |
[Polyneuritis and myositis in Trypanosoma gambiense infection].
Topics: Animals; Diagnosis, Differential; Drug Therapy, Combination; Electrocardiography; Electromyography; Hepatomegaly; Humans; Male; Melarsoprol; Middle Aged; Myositis; Polyneuropathies; Prednisolone; Splenomegaly; Suramin; Trypanosoma brucei gambiense; Trypanosomiasis, African | 1994 |
Drug sensitivity of Chinese Trypanosoma evansi and Trypanosoma equiperdum isolates.
Topics: Animals; Buffaloes; China; Diminazene; Drug Resistance; Female; Horses; Hypoxanthine; Hypoxanthines; Melarsoprol; Mice; Mice, Inbred ICR; Perissodactyla; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma | 1994 |
Innate lack of susceptibility of Ugandan Trypanosoma brucei rhodesiense to DL-alpha-difluoromethylornithine (DFMO).
Topics: Animals; Drug Resistance; Eflornithine; Female; Humans; Hypoxanthine; Hypoxanthines; Melarsoprol; Mice; Mice, Inbred ICR; Nifurtimox; Species Specificity; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda | 1995 |
Trypanocidal resistance in Trypanosoma evansi in vitro: effects of verapamil, cyproheptidine, desipramine and chlorpromazine alone and in combination with trypanocides.
Topics: Animals; Calcium Channel Blockers; Chlorpromazine; Cyproheptadine; Desipramine; Diminazene; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Multiple; Melarsoprol; Suramin; Trypanocidal Agents; Trypanosoma; Verapamil | 1996 |
Characterisation of cloned lines of Trypanosoma brucei expressing stable resistance to MelCy and suramin.
Topics: Animals; Arsenicals; Biological Assay; Cells, Cultured; Clone Cells; Drug Resistance; Female; Male; Melarsoprol; Mice; Mice, Inbred BALB C; Phenotype; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei | 1996 |
6-Phosphogluconate dehydrogenase from Trypanosoma brucei. Kinetic analysis and inhibition by trypanocidal drugs.
Topics: Animals; Arsenicals; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kinetics; Liver; Melarsoprol; Phosphogluconate Dehydrogenase; Sheep; Species Specificity; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei | 1996 |
[In vivo resistance to strains of Trypanosoma rhodesiense, Mozambique, 1985].
Topics: Animals; Drug Resistance; Humans; Melarsoprol; Mice; Suramin; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 1991 |
Rhodesian trypanosomiasis in a splenectomized patient.
Topics: Adult; Africa; Animals; Central Nervous System Diseases; Humans; Male; Melarsoprol; Splenectomy; Suramin; Travel; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 1999 |
Anti-sleeping sickness drugs and cancer chemotherapy.
Topics: Animals; Antineoplastic Agents; Eflornithine; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2000 |
Treatment of human African trypanosomiasis.
Topics: Acetanilides; Africa; Humans; Melarsoprol; Nitroimidazoles; Pentamidine; Suramin; Thiadiazoles; Trypanocidal Agents; Trypanosomiasis, African | 2000 |
Availability and affordability of treatment for Human African Trypanosomiasis.
Topics: Eflornithine; Health Services Accessibility; Humans; Melarsoprol; Pentamidine; Research; Suramin; Trypanocidal Agents; Trypanosomiasis, African; World Health Organization | 2001 |
Human African trypanosomiasis: potential therapeutic benefits of an alternative suramin and melarsoprol regimen.
Topics: Animals; Anti-Infective Agents, Local; Drug Synergism; Drug Therapy, Combination; Female; Humans; Melarsoprol; Mice; Parasitemia; Suramin; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2002 |
[The return of sleeping sickness in an epidemic form: international action for drugs].
Topics: Africa, Central; Animals; Disease Outbreaks; Eflornithine; Humans; International Cooperation; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African | 2002 |
Drug-resistance of Trypanosoma b. rhodesiense isolates from Tanzania.
Topics: Animals; Diminazene; Drug Resistance; Humans; Mass Screening; Melarsoprol; Phenanthridines; Recurrence; Suramin; Tanzania; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2006 |
Transverse myelitis due to trypanosomiasis in a middle aged Tanzanian man.
Topics: Animals; Developing Countries; Drug Therapy, Combination; Follow-Up Studies; Humans; Male; Melarsoprol; Middle Aged; Myelitis, Transverse; Neurologic Examination; Radiculopathy; Spinal Cord Compression; Suramin; Tanzania; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2006 |
A woman with fever and rash after African safari.
Topics: Africa; Exanthema; Female; Fever; Humans; Melarsoprol; Middle Aged; Pentamidine; Suramin; Travel; Trypanocidal Agents; Trypanosomiasis, African | 2006 |
Pentamidine movement across the murine blood-brain and blood-cerebrospinal fluid barriers: effect of trypanosome infection, combination therapy, P-glycoprotein, and multidrug resistance-associated protein.
Topics: Adenine; Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Disease Models, Animal; Drug Interactions; Eflornithine; Indomethacin; Male; Melarsoprol; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Knockout; Multidrug Resistance-Associated Proteins; Nifurtimox; Pentamidine; Perfusion; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African | 2009 |
Human African trypanosomiasis.
Topics: Africa; Animals; Biomedical Research; Communicable Disease Control; Eflornithine; Endemic Diseases; Humans; Incidence; Insect Bites and Stings; Insect Vectors; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African; Tsetse Flies; Variant Surface Glycoproteins, Trypanosoma | 2010 |
High-throughput decoding of antitrypanosomal drug efficacy and resistance.
Topics: Aquaglyceroporins; Drug Resistance; Eflornithine; Endocytosis; Glycosylation; High-Throughput Screening Assays; Humans; Lysosomes; Melarsoprol; Nifurtimox; Pentamidine; RNA Interference; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2012 |
Lesson of the month: a psychiatric diagnosis overturned by a blood film.
Topics: Antibodies, Protozoan; Cerebrospinal Fluid; Diagnosis, Differential; Female; Humans; Melarsoprol; Mental Disorders; Middle Aged; Parasitemia; Paresthesia; Spinal Puncture; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2012 |
Evaluation of trypanocidal drugs used for human African trypanosomosis against Trypanosoma lewisi.
Topics: Animals; Eflornithine; Female; Humans; Immunocompromised Host; Inhibitory Concentration 50; Melarsoprol; Mice; Nifurtimox; Nitroimidazoles; Parasitemia; Pentamidine; Rats; Rats, Wistar; Suramin; Trypanocidal Agents; Trypanosoma lewisi; Trypanosomiasis | 2013 |
Insights into antitrypanosomal drug mode-of-action from cytology-based profiling.
Topics: Cell Biology; Humans; Lysosomes; Melarsoprol; Mitochondria; Mitochondrial Proteins; Mitosis; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2018 |
Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model.
Topics: Animals; Diminazene; Disease Models, Animal; Drug Resistance; Kenya; Male; Melarsoprol; Mice; Pentamidine; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda; Virulence | 2020 |