Page last updated: 2024-08-21

melarsoprol and suramin

melarsoprol has been researched along with suramin in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	23 (36.51)	18.7374
1990's	13 (20.63)	18.2507
2000's	14 (22.22)	29.6817
2010's	12 (19.05)	24.3611
2020's	1 (1.59)	2.80

Authors

Authors	Studies
Berger, H; Brun, R; Kaiser, M; Saf, R; Seebacher, W; Weis, R	1
Büchold, C; Gelhaus, C; Gut, J; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Stempka, M	1
Breuning, A; Büchold, C; Degel, B; Gelhaus, C; Gut, J; Heppner, S; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rath, J; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Schulz, F; Stempka, M; Stich, A	1
Brun, R; Fotie, J; Gershkovich, P; He, S; Liu, Q; Patrick, DA; Premalatha, K; Reid, CS; Tidwell, RR; Wang, MZ; Wasan, KM; Wenzler, T; Werbovetz, KA	1
Clayton, C; De Muylder, G; Gerwick, L; Helbig, C; Knudsen, GM; Linington, RG; Mackey, ZB; Mascuch, SM; McKerrow, JH; Sanchez, LM	1
Ariën, KK; Augustyns, K; Cos, P; Dirié, B; Heeres, J; Joossens, J; Lewi, PJ; Lyssens, S; Maes, L; Michiels, J; Van der Veken, P; Vanham, G; Venkatraj, M	1
Ambuehl, C; Breant, L; Christen, P; Cretton, S; Cuendet, M; Ebrahimi, SN; Hamburger, M; Kaiser, M; Karimou, S; Marcourt, L; Perozzo, R; Pourrez, L	1
Brantner, A; Brun, R; Bucar, F; Faist, J; Gröblacher, B; Kaiser, M; Kalia, Y; Merino, V; Perozzo, R; Saf, R; Scapozza, L; Seebacher, W; Weis, R; Wolkinger, V	1
Williamson, J	1
Goodwin, LG; Tierney, ED	1
Brodsky, RE; Gibson, JJ; Schultz, MG; Spencer, HC	1
Foulkes, JR	1
Buyst, H	1
Buyst, H; Jones, IG; Lowenthal, MN	1
Ormerod, WE; Raseroka, BH	1
Bales, JD; Harrison, SM; Mbwabi, DL; Schecter, PJ	1
Thomson, KD	1
Baeriswyl, S; Brun, R; Kunz, C	1
Chumo, DA; Muriithi, RM; Mwangi, J; Reardon, MJ; Towett, S; Wellde, BT	1
Abinya, A; Chumo, DA; Dola, S; Mbwabi, D; Reardon, MJ; Siongok, TA; Smith, DH; Wanyama, L; Wellde, BT	1
Lefrock, JL; Smith, BR	1
Bouteille, B; Darde, ML; Pestre-Alexandre, M	1
Gutteridge, WE	1
Balber, AE; Frommel, TO	1
van der Meer, C; Versluijs-Broers, JA	1
Agbowu, J; Ajayi, N; Weir, AB	1
Wu, SH	1
Dukes, P	1
Barrett-Connor, E	1
Hall, JE; Seed, JR; Shertzer, HG	1
Boa Yapo, F; Doua, F	1
Roberts, JF; Yunmbam, MK	1
Dadzie, S; Kimata, DM; Makawiti, DW; Tengekyon, KM; Waindi, EN	1
Burkardt, H; Damian, MS; Dorndorf, W; Leinweber, B; Schachenmayr, W; Singer, I	1
Brun, R; Lun, ZR	1
Milord, F; Pépin, J	1
Brun, R; Iten, M; Kaminsky, R; Matovu, E	1
Anene, BM; Anika, SM; Chukwu, CC; Ross, CA	1
Scott, AG; Tait, A; Turner, CM	1
Barrett, MP; Bertelli, M; Dallocchio, F; Hanau, S; Rippa, M	1
Bales, JD; Harris, RW; Harrison, SM	1
Lastre González, M; Pérez Martín, O; Shwalbach, J; Urban, M	1
Boken, D; Malesker, MA; Murphy, PJ; Ruma, TA; Smith, PW; Vuchetich, PJ	1
Barrett, MP; Barrett, SV	1
Bouteille, B; Dumas, M	1
Etchegorry, MG; Helenport, JP; Jannin, J; Legros, D; Pecoul, B	1
Bradley, B; Gettinby, G; Jennings, FW; Kennedy, PG; Murray, M; Rodgers, J	1
Kager, PA	1
Nok, AJ	1
Docampo, R; Moreno, SN	1
Kaboya, JS; Kibona, SN; Lubega, GW; Matemba, L	1
Kibiki, GS; Murphy, DK	1
Berbari, EF; Jacobson, KM; Kumar, N; Orenstein, R; Uslan, DZ	1
De Koning, HP; Dogruel, M; Rodgers, J; Sanderson, L; Thomas, SA	1
Blum, J; Brun, R; Burri, C; Chappuis, F	1
Schlitzer, M	1
Alsford, S; Baker, N; Berriman, M; Eckert, S; Field, MC; Glover, L; Horn, D; Leung, KF; Sanchez-Flores, A; Turner, DJ	1
Bailey, R; Brown, M; Easom, N; Watson, J; Wise, E	1
Allan, M; Blum, J; Burri, C; Edielu, A; Haary, EP; Kakembo, A; Kibona, S; Kuepfer, I; Schmid, C	1
Bucheton, B; Courtois, P; Cuny, G; Daulouède, S; Dethoua, M; Nzoumbou-Boko, R; Semballa, S; Truc, P; Vincendeau, P	1
Alsford, S; Baker, N; Dominicus, C; Glover, L; Horn, D; Hutchinson, S; Thomas, JA; Trenaman, A	1
Auma, JE; Chemuliti, JK; Gitonga, PK; Kurgat, RK; Mdachi, RE; Murilla, GA; Ndung'u, K; Ngae, GN; Thuita, JK; Thungu, DK	1

Reviews

7 review(s) available for melarsoprol and suramin

Article	Year
Chemotherapy of African trypanosomiasis. Tropical diseases bulletin, 1976, Volume: 73, Issue:7 Topics: Adult; Amidines; Animals; Cattle; Drug Resistance; Drug Therapy, Combination; Humans; Melarsoprol; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine	1976
Existing chemotherapy and its limitations. British medical bulletin, 1985, Volume: 41, Issue:2 Topics: Chagas Disease; Gentian Violet; Humans; Melarsoprol; Nifurtimox; Nitroimidazoles; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African	1985
Drugs for the treatment of parasitic infection. The Medical clinics of North America, 1982, Volume: 66, Issue:1 Topics: Antimony; Bithionol; Chloroquine; Diethylcarbamazine; Humans; Mebendazole; Melarsoprol; Metronidazole; Niclosamide; Niridazole; Oxamniquine; Parasitic Diseases; Pentamidine; Piperazines; Primaquine; Pyrantel Pamoate; Pyrimethamine; Suramin; Thiabendazole; Trichlorfon	1982
The treatment of human African trypanosomiasis. Advances in parasitology, 1994, Volume: 33 Topics: Animals; Diminazene; Eflornithine; Humans; Melarsoprol; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	1994
Arsenicals (melarsoprol), pentamidine and suramin in the treatment of human African trypanosomiasis. Parasitology research, 2003, Volume: 90, Issue:1 Topics: Animals; Drug Resistance; HIV; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2003
Current chemotherapy of human African trypanosomiasis. Parasitology research, 2003, Volume: 90 Supp 1 Topics: Animals; Eflornithine; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African	2003
[Agents for the treatment of African sleeping sickness. Those developed in the last century]. Pharmazie in unserer Zeit, 2009, Volume: 38, Issue:6 Topics: Animals; Eflornithine; History, 20th Century; Humans; Melarsoprol; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African	2009

Trials

2 trial(s) available for melarsoprol and suramin

Article	Year
Attempt to correlate urine arsenic excretion with clinical course during melarsoprol therapy of patients with Rhodesian trypanosomiasis. The American journal of tropical medicine and hygiene, 1997, Volume: 56, Issue:6 Topics: Adolescent; Adult; Aged; Animals; Arsenic; Child; Child, Preschool; Creatinine; Drug Therapy, Combination; Female; Humans; Male; Melarsoprol; Middle Aged; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	1997
Safety and efficacy of the 10-day melarsoprol schedule for the treatment of second stage Rhodesiense sleeping sickness. PLoS neglected tropical diseases, 2012, Volume: 6, Issue:8 Topics: Adolescent; Adult; Aged; Brain Diseases; Child; Drug Administration Schedule; Endemic Diseases; Female; Humans; Male; Melarsoprol; Middle Aged; Suramin; Tanzania; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda	2012

Article

Year

Attempt to correlate urine arsenic excretion with clinical course during melarsoprol therapy of patients with Rhodesian trypanosomiasis.

The American journal of tropical medicine and hygiene, 1997, Volume: 56, Issue:6

Topics: Adolescent; Adult; Aged; Animals; Arsenic; Child; Child, Preschool; Creatinine; Drug Therapy, Combination; Female; Humans; Male; Melarsoprol; Middle Aged; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

1997

Safety and efficacy of the 10-day melarsoprol schedule for the treatment of second stage Rhodesiense sleeping sickness.

PLoS neglected tropical diseases, 2012, Volume: 6, Issue:8

Topics: Adolescent; Adult; Aged; Brain Diseases; Child; Drug Administration Schedule; Endemic Diseases; Female; Humans; Male; Melarsoprol; Middle Aged; Suramin; Tanzania; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda

2012

Other Studies

54 other study(ies) available for melarsoprol and suramin

Article	Year
Antiprotozoal activities of new bis-chlorophenyl derivatives of bicyclic octanes and aza-nonanes. Bioorganic & medicinal chemistry letters, 2006, Oct-15, Volume: 16, Issue:20 Topics: Animals; Antiprotozoal Agents; Bridged Bicyclo Compounds, Heterocyclic; In Vitro Techniques; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Stereoisomerism; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense	2006
On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences. Journal of medicinal chemistry, 2009, Sep-24, Volume: 52, Issue:18 Topics: Amino Acid Sequence; Animals; Antiprotozoal Agents; Cathepsin L; Cathepsins; Cattle; Combinatorial Chemistry Techniques; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diamide; Drug Evaluation, Preclinical; Fumarates; Humans; Peptide Library; Plasmodium falciparum	2009
Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids. Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5 Topics: Antimalarials; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei	2010
Synthesis and antitrypanosomal evaluation of derivatives of N-benzyl-1,2-dihydroquinolin-6-ols: Effect of core substitutions and salt formation. Bioorganic & medicinal chemistry, 2011, Jan-01, Volume: 19, Issue:1 Topics: Animals; Cyclization; Mice; Quinolines; Salts; Structure-Activity Relationship; Trypanocidal Agents	2011
Examination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei. Journal of natural products, 2013, Apr-26, Volume: 76, Issue:4 Topics: Animals; Biological Products; Chagas Disease; Glycolysis; Humans; Leishmania donovani; Lipopeptides; Microbodies; Microscopy, Fluorescence; Trypanosoma brucei brucei; Zebrafish	2013
From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds. Bioorganic & medicinal chemistry, 2014, Oct-01, Volume: 22, Issue:19 Topics: Anti-HIV Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense	2014
Antitrypanosomal quinoline alkaloids from the roots of Waltheria indica. Journal of natural products, 2014, Oct-24, Volume: 77, Issue:10 Topics: Alkaloids; Animals; Inhibitory Concentration 50; Malvaceae; Mice; Molecular Structure; Niger; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Quinolines; Trypanocidal Agents; Trypanosoma	2014
Synthesis of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities. Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7 Topics: Administration, Oral; Animals; Antiprotozoal Agents; Azabicyclo Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Rats; Structure-Activity Relationship; Tissue Distribution; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2015
Chemotherapy of sleeping sickness. The Central African journal of medicine, 1979, Volume: 25, Issue:11 Topics: Arsenicals; Humans; Melarsoprol; Pentamidine; Suramin; Trypanosomiasis, African	1979
Trypanocidal activity of blood and tissue fluid from normal and infected rabbits treated with curative drugs. Parasitology, 1977, Volume: 74, Issue:1 Topics: Animals; Benzamidines; Body Fluids; Diminazene; Ethidium; Male; Melarsoprol; Mice; Phenanthridines; Rabbits; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis	1977
Imported African trypanosomiasis in the United States. Annals of internal medicine, 1975, Volume: 82, Issue:5 Topics: Adult; Aged; Diagnosis, Differential; Female; Humans; Male; Melarsoprol; Middle Aged; Suramin; Trypanosomiasis, African; United States	1975
An evaluation of prednisolone as a routine adjunct to the treatment of T. rhodesiense. The Journal of tropical medicine and hygiene, 1975, Volume: 78, Issue:4 Topics: Adult; Arsenicals; Child; Drug Administration Schedule; Drug Evaluation, Preclinical; Humans; Melarsoprol; Meningoencephalitis; Prednisolone; Suramin; Trypanosoma; Trypanosomiasis, African; Zambia	1975
The treatment of T. rhodesiense sleeping sickness, with special reference to its physio-pathological and epidemiological basis. Annales de la Societe belge de medecine tropicale, 1975, Volume: 55, Issue:2 Topics: Arsenicals; Chloroquine; Humans; Melarsoprol; Proguanil; Suramin; Trypanosomiasis, African; Zambia	1975
Electrocardiographic changes in African trypanosomiasis caused by Trypanosoma brucei rhodesiense. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1975, Volume: 69, Issue:4 Topics: Adolescent; Adult; Aged; Electrocardiography; Female; Heart Diseases; Humans; Male; Melarsoprol; Middle Aged; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African	1975
Screening compounds for sleeping sickness therapy without relapse. Bulletin de la Societe de pathologie exotique et de ses filiales, 1988, Volume: 81, Issue:3 Pt 2 Topics: Animals; Bleomycin; Drug Evaluation, Preclinical; Eflornithine; Melarsoprol; Metronidazole; Mice; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1988
Treatment of arsenical refractory Rhodesian sleeping sickness in Kenya. Annals of tropical medicine and parasitology, 1989, Volume: 83 Suppl 1 Topics: Adult; Animals; Arsenicals; Drug Therapy, Combination; Eflornithine; Female; Humans; Kenya; Male; Melarsoprol; Middle Aged; Recurrence; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African	1989
Tryparsamide. Lancet (London, England), 1989, Sep-02, Volume: 2, Issue:8662 Topics: Drug Therapy, Combination; Humans; Melarsoprol; Nigeria; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African	1989
In vitro drug sensitivity of Trypanosoma gambiense isolates. Acta tropica, 1989, Volume: 46, Issue:5-6 Topics: Animals; Arsenicals; Cote d'Ivoire; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African	1989
Experimental infection of goats with Trypanosoma brucei ssp. and effects of treatment with suramin and Mel-B. Annals of tropical medicine and parasitology, 1989, Volume: 83 Suppl 1 Topics: Animals; Arsenicals; Brain; Central Nervous System; Central Nervous System Diseases; Goat Diseases; Goats; Male; Melarsoprol; Mice; Spinal Puncture; Suramin; Trypanocidal Agents; Trypanosomiasis, African	1989
Treatment of Rhodesian sleeping sickness in Kenya. Annals of tropical medicine and parasitology, 1989, Volume: 83 Suppl 1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Arsenicals; Child; Drug Resistance; Female; Follow-Up Studies; Humans; Kenya; Male; Melarsoprol; Middle Aged; Prospective Studies; Recurrence; Retrospective Studies; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1989
Drugs for protozoan infections. American family physician, 1987, Volume: 35, Issue:3 Topics: Antimalarials; Antimony Sodium Gluconate; Antiprotozoal Agents; Humans; Iodoquinol; Melarsoprol; Metronidazole; Nifurtimox; Pentamidine; Protozoan Infections; Suramin	1987
[Action of drugs tested in an acellular medium and in mice infected with Trypanosoma brucei brucei]. Bulletin de la Societe de pathologie exotique et de ses filiales, 1988, Volume: 81, Issue:3 Pt 2 Topics: Acetanilides; Animals; Culture Media; Cyclosporins; Eflornithine; In Vitro Techniques; Melarsoprol; Mice; Mitoguazone; Nitroimidazoles; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1988
Flow cytofluorimetric analysis of drug accumulation by multidrug-resistant Trypanosoma brucei brucei and T. b. rhodesiense. Molecular and biochemical parasitology, 1987, Volume: 26, Issue:1-2 Topics: Acriflavine; Animals; Benzimidazoles; Diminazene; Drug Resistance; Ethidium; Flow Cytometry; Fluorescent Dyes; Humans; Indoles; Melarsoprol; Mice; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei	1987
Trypanosoma brucei and T. vivax: salicylhydroxamic acid and glycerol treatment of acute and chronically infected rats. Experimental parasitology, 1986, Volume: 62, Issue:1 Topics: Animals; Brain; Drug Administration Schedule; Drug Therapy, Combination; Female; Glycerol; Melarsoprol; Mice; Muscles; Rats; Rats, Inbred Strains; Salicylamides; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis; Trypanosomiasis, African	1986
Hyperendemic West African trypanosomiasis in a rural hospital setting. The Journal of tropical medicine and hygiene, 1985, Volume: 88, Issue:5 Topics: Brain Diseases; Dexamethasone; Drug Administration Schedule; Drug Therapy, Combination; Hospitals, Rural; Humans; Melarsoprol; Nigeria; Suramin; Trypanosomiasis, African	1985
African human trypanosomiasis in southern Sudan. Report of 77 cases. Chinese medical journal, 1985, Volume: 98, Issue:1 Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Male; Melarsoprol; Middle Aged; Sudan; Suramin; Trypanosomiasis, African	1985
Arsenic and old taxa: subspeciation and drug sensitivity in Trypanosoma brucei. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1984, Volume: 78, Issue:6 Topics: Animals; Arsenicals; Diminazene; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Isoenzymes; Male; Melarsoprol; Mice; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1984
Hepatic mixed-function oxidase activity in mice infected with Trypanosoma brucei gambiense or treated with trypanocides. Molecular and biochemical parasitology, 1981, Volume: 3, Issue:4 Topics: Animals; Arsenicals; Cytochrome P-450 Enzyme System; Liver; Male; Melarsoprol; Mice; Mixed Function Oxygenases; Oxidoreductases; Pentobarbital; Sleep; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African	1981
[Current therapy of trypanosomiasis]. Bulletin de la Societe de pathologie exotique (1990), 1994, Volume: 87, Issue:5 Topics: Adenosylmethionine Decarboxylase; Animals; Arsenicals; Deoxyadenosines; Drug Resistance; Eflornithine; Enzyme Inhibitors; Hospitalization; Humans; Melarsoprol; Pentamidine; Randomized Controlled Trials as Topic; Recurrence; Suramin; Triazines; Trypanocidal Agents; Trypanosomiasis, African	1994
In vivo evaluation of reuterin and its combinations with suramin, melarsoprol, DL-alpha-difluoromethylornithine and bleomycin in mice infected with Trypanosoma brucei brucei. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1993, Volume: 105, Issue:3 Topics: Aldehydes; Animals; Anti-Bacterial Agents; Bleomycin; Drug Therapy, Combination; Eflornithine; Female; Glyceraldehyde; Lethal Dose 50; Melarsoprol; Mice; Propane; Suramin; Trypanosomiasis, African	1993
Delayed recovery of adrenocortical and testicular function after chemotherapy of human trypanosomiasis. Acta tropica, 1994, Volume: 57, Issue:1 Topics: Adolescent; Adrenal Cortex; Adult; Aged; Anemia; Animals; Hematocrit; Humans; Hydrocortisone; Hypogonadism; Luteinizing Hormone; Male; Melarsoprol; Middle Aged; Suramin; Testis; Testosterone; Time Factors; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	1994
[Polyneuritis and myositis in Trypanosoma gambiense infection]. Deutsche medizinische Wochenschrift (1946), 1994, Dec-09, Volume: 119, Issue:49 Topics: Animals; Diagnosis, Differential; Drug Therapy, Combination; Electrocardiography; Electromyography; Hepatomegaly; Humans; Male; Melarsoprol; Middle Aged; Myositis; Polyneuropathies; Prednisolone; Splenomegaly; Suramin; Trypanosoma brucei gambiense; Trypanosomiasis, African	1994
Drug sensitivity of Chinese Trypanosoma evansi and Trypanosoma equiperdum isolates. Veterinary parasitology, 1994, Volume: 52, Issue:1-2 Topics: Animals; Buffaloes; China; Diminazene; Drug Resistance; Female; Horses; Hypoxanthine; Hypoxanthines; Melarsoprol; Mice; Mice, Inbred ICR; Perissodactyla; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma	1994
Innate lack of susceptibility of Ugandan Trypanosoma brucei rhodesiense to DL-alpha-difluoromethylornithine (DFMO). Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1995, Volume: 46, Issue:3 Topics: Animals; Drug Resistance; Eflornithine; Female; Humans; Hypoxanthine; Hypoxanthines; Melarsoprol; Mice; Mice, Inbred ICR; Nifurtimox; Species Specificity; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda	1995
Trypanocidal resistance in Trypanosoma evansi in vitro: effects of verapamil, cyproheptidine, desipramine and chlorpromazine alone and in combination with trypanocides. Veterinary parasitology, 1996, Volume: 62, Issue:1-2 Topics: Animals; Calcium Channel Blockers; Chlorpromazine; Cyproheptadine; Desipramine; Diminazene; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Multiple; Melarsoprol; Suramin; Trypanocidal Agents; Trypanosoma; Verapamil	1996
Characterisation of cloned lines of Trypanosoma brucei expressing stable resistance to MelCy and suramin. Acta tropica, 1996, Volume: 60, Issue:4 Topics: Animals; Arsenicals; Biological Assay; Cells, Cultured; Clone Cells; Drug Resistance; Female; Male; Melarsoprol; Mice; Mice, Inbred BALB C; Phenotype; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei	1996
6-Phosphogluconate dehydrogenase from Trypanosoma brucei. Kinetic analysis and inhibition by trypanocidal drugs. European journal of biochemistry, 1996, Sep-15, Volume: 240, Issue:3 Topics: Animals; Arsenicals; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kinetics; Liver; Melarsoprol; Phosphogluconate Dehydrogenase; Sheep; Species Specificity; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei	1996
[In vivo resistance to strains of Trypanosoma rhodesiense, Mozambique, 1985]. Revista cubana de medicina tropical, 1991, Volume: 43, Issue:3 Topics: Animals; Drug Resistance; Humans; Melarsoprol; Mice; Suramin; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	1991
Rhodesian trypanosomiasis in a splenectomized patient. The American journal of tropical medicine and hygiene, 1999, Volume: 61, Issue:3 Topics: Adult; Africa; Animals; Central Nervous System Diseases; Humans; Male; Melarsoprol; Splenectomy; Suramin; Travel; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	1999
Anti-sleeping sickness drugs and cancer chemotherapy. Parasitology today (Personal ed.), 2000, Volume: 16, Issue:1 Topics: Animals; Antineoplastic Agents; Eflornithine; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2000
Treatment of human African trypanosomiasis. Bulletin of the World Health Organization, 2000, Volume: 78, Issue:12 Topics: Acetanilides; Africa; Humans; Melarsoprol; Nitroimidazoles; Pentamidine; Suramin; Thiadiazoles; Trypanocidal Agents; Trypanosomiasis, African	2000
Availability and affordability of treatment for Human African Trypanosomiasis. Tropical medicine & international health : TM & IH, 2001, Volume: 6, Issue:11 Topics: Eflornithine; Health Services Accessibility; Humans; Melarsoprol; Pentamidine; Research; Suramin; Trypanocidal Agents; Trypanosomiasis, African; World Health Organization	2001
Human African trypanosomiasis: potential therapeutic benefits of an alternative suramin and melarsoprol regimen. Parasitology international, 2002, Volume: 51, Issue:4 Topics: Animals; Anti-Infective Agents, Local; Drug Synergism; Drug Therapy, Combination; Female; Humans; Melarsoprol; Mice; Parasitemia; Suramin; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2002
[The return of sleeping sickness in an epidemic form: international action for drugs]. Nederlands tijdschrift voor geneeskunde, 2002, Dec-28, Volume: 146, Issue:52 Topics: Africa, Central; Animals; Disease Outbreaks; Eflornithine; Humans; International Cooperation; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African	2002
Drug-resistance of Trypanosoma b. rhodesiense isolates from Tanzania. Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:2 Topics: Animals; Diminazene; Drug Resistance; Humans; Mass Screening; Melarsoprol; Phenanthridines; Recurrence; Suramin; Tanzania; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2006
Transverse myelitis due to trypanosomiasis in a middle aged Tanzanian man. Journal of neurology, neurosurgery, and psychiatry, 2006, Volume: 77, Issue:5 Topics: Animals; Developing Countries; Drug Therapy, Combination; Follow-Up Studies; Humans; Male; Melarsoprol; Middle Aged; Myelitis, Transverse; Neurologic Examination; Radiculopathy; Spinal Cord Compression; Suramin; Tanzania; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2006
A woman with fever and rash after African safari. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Sep-01, Volume: 43, Issue:5 Topics: Africa; Exanthema; Female; Fever; Humans; Melarsoprol; Middle Aged; Pentamidine; Suramin; Travel; Trypanocidal Agents; Trypanosomiasis, African	2006
Pentamidine movement across the murine blood-brain and blood-cerebrospinal fluid barriers: effect of trypanosome infection, combination therapy, P-glycoprotein, and multidrug resistance-associated protein. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3 Topics: Adenine; Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Disease Models, Animal; Drug Interactions; Eflornithine; Indomethacin; Male; Melarsoprol; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Knockout; Multidrug Resistance-Associated Proteins; Nifurtimox; Pentamidine; Perfusion; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African	2009
Human African trypanosomiasis. Lancet (London, England), 2010, Jan-09, Volume: 375, Issue:9709 Topics: Africa; Animals; Biomedical Research; Communicable Disease Control; Eflornithine; Endemic Diseases; Humans; Incidence; Insect Bites and Stings; Insect Vectors; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African; Tsetse Flies; Variant Surface Glycoproteins, Trypanosoma	2010
High-throughput decoding of antitrypanosomal drug efficacy and resistance. Nature, 2012, Jan-25, Volume: 482, Issue:7384 Topics: Aquaglyceroporins; Drug Resistance; Eflornithine; Endocytosis; Glycosylation; High-Throughput Screening Assays; Humans; Lysosomes; Melarsoprol; Nifurtimox; Pentamidine; RNA Interference; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2012
Lesson of the month: a psychiatric diagnosis overturned by a blood film. Clinical medicine (London, England), 2012, Volume: 12, Issue:3 Topics: Antibodies, Protozoan; Cerebrospinal Fluid; Diagnosis, Differential; Female; Humans; Melarsoprol; Mental Disorders; Middle Aged; Parasitemia; Paresthesia; Spinal Puncture; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2012
Evaluation of trypanocidal drugs used for human African trypanosomosis against Trypanosoma lewisi. Parasite (Paris, France), 2013, Volume: 20 Topics: Animals; Eflornithine; Female; Humans; Immunocompromised Host; Inhibitory Concentration 50; Melarsoprol; Mice; Nifurtimox; Nitroimidazoles; Parasitemia; Pentamidine; Rats; Rats, Wistar; Suramin; Trypanocidal Agents; Trypanosoma lewisi; Trypanosomiasis	2013
Insights into antitrypanosomal drug mode-of-action from cytology-based profiling. PLoS neglected tropical diseases, 2018, Volume: 12, Issue:11 Topics: Cell Biology; Humans; Lysosomes; Melarsoprol; Mitochondria; Mitochondrial Proteins; Mitosis; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2018
Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model. PloS one, 2020, Volume: 15, Issue:11 Topics: Animals; Diminazene; Disease Models, Animal; Drug Resistance; Kenya; Male; Melarsoprol; Mice; Pentamidine; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda; Virulence	2020