Page last updated: 2024-08-21

melarsoprol and diminazene

melarsoprol has been researched along with diminazene in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (24.00)	18.7374
1990's	6 (24.00)	18.2507
2000's	5 (20.00)	29.6817
2010's	6 (24.00)	24.3611
2020's	2 (8.00)	2.80

Authors

Authors	Studies
Brun, R; de Koning, HP; Gould, M; Kaiser, M; Koomen, GJ; Rodenko, B; van der Burg, AM; Wanner, MJ	1
Delfín, DA; Fotie, J; Kaiser, M; Li, C; Maes, L; Mahasenan, KV; Manley, J; Paris, JM; Reid, CS; Wenzler, T; Werbovetz, KA	1
Brun, R; Fotie, J; Gershkovich, P; He, S; Liu, Q; Patrick, DA; Premalatha, K; Reid, CS; Tidwell, RR; Wang, MZ; Wasan, KM; Wenzler, T; Werbovetz, KA	1
Capes, A; Collie, IT; Fairlamb, AH; Frearson, JA; Gilbert, IH; Hallyburton, I; McCarroll, AJ; Patterson, S; Stevens, MF; Wyatt, PG; Wyllie, S	1
Alkhaldi, AA; Chana, A; Dardonville, C; de Koning, HP; Eze, AA; Flores Pérez, EJ; Healy, A; Herrero García, V; Kaiser, M; Ríos Martínez, C; Taladriz, A	1
Abdel-Megeed, AM; Avery, VM; Baell, JB; Brown, RW; Hyland, CJT; Jones, AJ; Kaiser, M; Keller, PA; Sykes, ML	1
Goodwin, LG; Tierney, ED	1
Kaminsky, R; Zweygarth, E	1
Balber, AE; Frommel, TO	1
Champalimaud, JL; Medina, EA; Ventura, FA	1
Borowy, NK; Fink, E; Hirumi, H	1
Dukes, P	1
Bruneel, H; Burke, J; Degroof, D; Molisho, D; Pépin, J; van den Eeckhout, A	1
Brun, R; Lun, ZR	1
Milord, F; Pépin, J	1
Anene, BM; Anika, SM; Chukwu, CC; Ross, CA	1
Brun, R; Enyaru, JC; Iten, M; Kaminsky, R; Lubega, GW; Matovu, E; Schmid, C	1
Scott, AG; Tait, A; Turner, CM	1
Barrett, MP; Brun, R; Burchmore, RJ; de Koning, HP; Enyaru, JC; Geiser, F; Kaminsky, R; Mäser, P; Matovu, E; Seebeck, T; Stewart, ML; Wallace, LJ	1
Kaboya, JS; Kibona, SN; Lubega, GW; Matemba, L	1
Lüscher, A; Mäser, P; Nerima, B	1
Kagira, JM; Maina, N	1
Farah, IO; Hau, J; Kagira, JM; Kariuki, C; Maina, N; Mwangangi, DM; Ngotho, M; Thuita, JK	1
Alkhaldi, AA; Alzahrani, KJ; De Koning, HP; Eze, AA; Krezdorn, JA; McDonald, F; Munday, JC; Rojas López, KE; Settimo, L; Still, J; Tagoe, DN	1
Auma, JE; Chemuliti, JK; Gitonga, PK; Kurgat, RK; Mdachi, RE; Murilla, GA; Ndung'u, K; Ngae, GN; Thuita, JK; Thungu, DK	1

Reviews

1 review(s) available for melarsoprol and diminazene

Article	Year
The treatment of human African trypanosomiasis. Advances in parasitology, 1994, Volume: 33 Topics: Animals; Diminazene; Eflornithine; Humans; Melarsoprol; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	1994

Other Studies

24 other study(ies) available for melarsoprol and diminazene

Article	Year
2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: Adenosine; Animals; Antimalarials; Dose-Response Relationship, Drug; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi	2007
Antitrypanosomal activity of 1,2-dihydroquinolin-6-ols and their ester derivatives. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Acetates; Animals; Cells, Cultured; Esters; Humans; Mice; Molecular Structure; Myoblasts; Quinolines; Rats; Reactive Oxygen Species; Structure-Activity Relationship; Survival Rate; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2010
Synthesis and antitrypanosomal evaluation of derivatives of N-benzyl-1,2-dihydroquinolin-6-ols: Effect of core substitutions and salt formation. Bioorganic & medicinal chemistry, 2011, Jan-01, Volume: 19, Issue:1 Topics: Animals; Cyclization; Mice; Quinolines; Salts; Structure-Activity Relationship; Trypanocidal Agents	2011
Quinol derivatives as potential trypanocidal agents. Bioorganic & medicinal chemistry, 2012, Feb-15, Volume: 20, Issue:4 Topics: Benzamidines; Cell Line; Drug Delivery Systems; Humans; Hydroquinones; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Triazines; Trypanocidal Agents; Trypanosoma brucei brucei	2012
Synthesis and structure-activity analysis of new phosphonium salts with potent activity against African trypanosomes. Journal of medicinal chemistry, 2012, Mar-22, Volume: 55, Issue:6 Topics: Carrier Proteins; Cell Line; Drug Resistance; Humans; Models, Molecular; Nucleoside Transport Proteins; Organophosphorus Compounds; Pentamidine; Quantitative Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense	2012
Investigation of thiazolyl-benzothiophenamides as potential agents for African sleeping sickness. RSC medicinal chemistry, 2020, Dec-17, Volume: 11, Issue:12 Topics:	2020
Trypanocidal activity of blood and tissue fluid from normal and infected rabbits treated with curative drugs. Parasitology, 1977, Volume: 74, Issue:1 Topics: Animals; Benzamidines; Body Fluids; Diminazene; Ethidium; Male; Melarsoprol; Mice; Phenanthridines; Rabbits; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis	1977
Effect of in vitro cultivation on the stability of resistance of Trypanosoma brucei brucei to diminazene, isometamidium, quinapyramine, and Mel B. The Journal of parasitology, 1989, Volume: 75, Issue:1 Topics: Animals; Anopheles; Cells, Cultured; Diminazene; Drug Resistance; Female; Male; Melarsoprol; Mice; Phenanthridines; Quinolinium Compounds; Trypanocidal Agents; Trypanosoma brucei brucei	1989
Flow cytofluorimetric analysis of drug accumulation by multidrug-resistant Trypanosoma brucei brucei and T. b. rhodesiense. Molecular and biochemical parasitology, 1987, Volume: 26, Issue:1-2 Topics: Acriflavine; Animals; Benzimidazoles; Diminazene; Drug Resistance; Ethidium; Flow Cytometry; Fluorescent Dyes; Humans; Indoles; Melarsoprol; Mice; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei	1987
Computer-assisted tomographic findings in a patient with African trypanosomiasis. The Journal of tropical medicine and hygiene, 1986, Volume: 89, Issue:2 Topics: Brain Diseases; Child, Preschool; Diminazene; Humans; Male; Melarsoprol; Meningoencephalitis; Recurrence; Tomography, X-Ray Computed; Trypanosomiasis, African	1986
Trypanosoma brucei: five commonly used trypanocides assayed in vitro with a mammalian feeder layer system for cultivation of bloodstream forms. Experimental parasitology, 1985, Volume: 60, Issue:3 Topics: Animals; Cattle; Cells, Cultured; Diminazene; Dose-Response Relationship, Drug; Melarsoprol; Phenanthridines; Quinolinium Compounds; Trypanocidal Agents; Trypanosoma brucei brucei	1985
Arsenic and old taxa: subspeciation and drug sensitivity in Trypanosoma brucei. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1984, Volume: 78, Issue:6 Topics: Animals; Arsenicals; Diminazene; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Isoenzymes; Male; Melarsoprol; Mice; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1984
[Control of Trypanosoma gambiense trypanosomiasis. Evaluation of a strategy based on the treatment of serologically suspected cases with a single dose of diminazene]. Annales de la Societe belge de medecine tropicale, 1994, Volume: 74, Issue:3 Topics: Agglutination Tests; Democratic Republic of the Congo; Diminazene; Humans; Incidence; Melarsoprol; Trypanosomiasis, African	1994
Drug sensitivity of Chinese Trypanosoma evansi and Trypanosoma equiperdum isolates. Veterinary parasitology, 1994, Volume: 52, Issue:1-2 Topics: Animals; Buffaloes; China; Diminazene; Drug Resistance; Female; Horses; Hypoxanthine; Hypoxanthines; Melarsoprol; Mice; Mice, Inbred ICR; Perissodactyla; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma	1994
Trypanocidal resistance in Trypanosoma evansi in vitro: effects of verapamil, cyproheptidine, desipramine and chlorpromazine alone and in combination with trypanocides. Veterinary parasitology, 1996, Volume: 62, Issue:1-2 Topics: Animals; Calcium Channel Blockers; Chlorpromazine; Cyproheptadine; Desipramine; Diminazene; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Multiple; Melarsoprol; Suramin; Trypanocidal Agents; Trypanosoma; Verapamil	1996
Susceptibility of Ugandan Trypanosoma brucei rhodesiense isolated from man and animal reservoirs to diminazene, isometamidium and melarsoprol. Tropical medicine & international health : TM & IH, 1997, Volume: 2, Issue:1 Topics: Animals; Diminazene; Humans; Melarsoprol; Phenanthridines; Trypanocidal Agents; Trypanosoma brucei rhodesiense	1997
Trypanosoma brucei: lack of cross-resistance to melarsoprol in vitro by cymelarsan-resistant parasites. Experimental parasitology, 1997, Volume: 86, Issue:3 Topics: Adenine; Adenosine; Animals; Arsenicals; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Female; Inosine; Melarsoprol; Mice; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei	1997
Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei. Eukaryotic cell, 2003, Volume: 2, Issue:5 Topics: Adenine; Adenosine; Animals; Arsenicals; Benzamidines; Cell Death; Cell Division; Diminazene; Drug Resistance; Female; Gene Silencing; Hypoxanthine; Inhibitory Concentration 50; Inosine; Melarsoprol; Mice; Mutation; Nucleoside Transport Proteins; Pentamidine; Stilbamidines; Trypanosoma brucei brucei	2003
Drug-resistance of Trypanosoma b. rhodesiense isolates from Tanzania. Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:2 Topics: Animals; Diminazene; Drug Resistance; Humans; Mass Screening; Melarsoprol; Phenanthridines; Recurrence; Suramin; Tanzania; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2006
Combined contribution of TbAT1 and TbMRPA to drug resistance in Trypanosoma brucei. Molecular and biochemical parasitology, 2006, Volume: 150, Issue:2 Topics: Animals; Diminazene; Drug Resistance; Inhibitory Concentration 50; Melarsoprol; Membrane Transport Proteins; Nucleoside Transport Proteins; Protozoan Proteins; Trypanocidal Agents; Trypanosoma brucei brucei	2006
Occurrence of multiple drug resistance in Trypanosoma brucei rhodesiense isolated from sleeping sickness patients. The Onderstepoort journal of veterinary research, 2007, Volume: 74, Issue:1 Topics: Animals; Diminazene; Drug Resistance, Multiple; Humans; Kenya; Melarsoprol; Mice; Parasitic Sensitivity Tests; Phenanthridines; Random Allocation; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda	2007
Influence of trypanocidal therapy on the haematology of vervet monkeys experimentally infected with Trypanosoma brucei rhodesiense. Acta tropica, 2011, Volume: 119, Issue:1 Topics: Anemia, Macrocytic; Animals; Blood Platelets; Cerebrospinal Fluid; Chlorocebus aethiops; Diminazene; Disease Models, Animal; Female; Hematology; Leukocytes; Male; Melarsoprol; Thrombocytopenia; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2011
Functional analysis of drug resistance-associated mutations in the Trypanosoma brucei adenosine transporter 1 (TbAT1) and the proposal of a structural model for the protein. Molecular microbiology, 2015, Volume: 96, Issue:4 Topics: Alleles; Diminazene; Drug Resistance, Multiple; Kinetics; Melarsoprol; Models, Molecular; Mutation; Nucleoside Transport Proteins; Parasitic Sensitivity Tests; Pentamidine; Polymorphism, Single Nucleotide; Protein Interaction Domains and Motifs; Trypanocidal Agents; Trypanosoma brucei brucei	2015
Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model. PloS one, 2020, Volume: 15, Issue:11 Topics: Animals; Diminazene; Disease Models, Animal; Drug Resistance; Kenya; Male; Melarsoprol; Mice; Pentamidine; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda; Virulence	2020