Page last updated: 2024-08-21

melarsoprol and chloroquine

melarsoprol has been researched along with chloroquine in 105 studies

Research

Studies (105)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (3.81)	18.7374
1990's	0 (0.00)	18.2507
2000's	37 (35.24)	29.6817
2010's	57 (54.29)	24.3611
2020's	7 (6.67)	2.80

Authors

Authors	Studies
Berecibar, A; Davioud-Charvet, E; Debreu, MA; Girault, S; Grellier, P; Lemière, P; Maes, L; Mouray, E; Sergheraert, C	1
Goclik, E; Kaminsky, R; König, GM; Wright, AD	2
Bringmann, G; Brun, R; Günther, C; Hamm, A; Michel, M; Mudogo, V	1
Bringmann, G; Brun, R; Christensen, SB; Dalsgaard, PW; Dreyer, M; Faber, JH; Jaroszewski, JW; Maksimenka, K; Mbago, F; Ndangalasi, H; Reichert, M; Staerk, D	1
Bringmann, G; Brun, R; Christensen, SB; Dalsgaard, PW; Dreyer, M; Faber, JH; Jaroszewski, JW; Mbago, F; Ndangalasi, H; Staerk, D	1
Bringmann, G; Brun, R; Dreyer, M; Hadi, HA; Heubl, G; Meimberg, H; Rischer, H; Wolf, K	1
König, GM; Papendorf, O; Wright, AD	1
Brun, R; Cimanga, K; Dommisse, R; Hostyn, S; Kaiser, M; Lemière, G; Maes, BU; Mátyus, P; Pieters, L; Van Miert, S; Vlietinck, A	1
Bringmann, G; Brun, R; Dreyer, M; Hadi, HA; Heubl, G; Kopff, H; Meimberg, H; Rischer, H; Wohlfarth, M	1
Berger, H; Brun, R; Kaiser, M; Saf, R; Seebacher, W; Weis, R	2
Ahua, KM; Brun, R; Diallo, D; Hay, AE; Hostettmann, K; Ioset, JR	1
Beauchene, J; Caffrey, CR; Cohen, FE; Debnath, A; Doyle, PS; Fafarman, AT; Fairlamb, AH; Kelly, B; Land, KM; May, BC; McKerrow, JH; Moll, H; Ponte-Sucre, A; Saravanamuthu, A; Schirmeister, T; Schreiber, K; Steverding, D; Swenerton, RK; Walshe, D; Weisman, JL; Zhou, YM; Zorn, JA	1
Bakunov, SA; Bakunova, SM; Bridges, AS; Brun, R; Hall, JE; Jones, SK; Kumar, EV; Lombardy, RJ; Patrick, DA; Tidwell, RR; Wenzler, T; Zhirnov, O	1
Brun, R; Kaiser, M; Saf, R; Schlapper, C; Seebacher, W; Weis, R	2
Brun, R; de Koning, HP; Gould, M; Kaiser, M; Koomen, GJ; Rodenko, B; van der Burg, AM; Wanner, MJ	1
Brun, R; Gunzenhauser, S; Senn, M; Séquin, U	1
Bakunov, SA; Bakunova, SM; Barszcz, T; Brun, R; Hall, JE; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Brun, R; Kaiser, M; Kuettel, S; Perozzo, R; Scapozza, L; Zambon, A	1
Brun, R; Dardonville, C; García, RN; Kaiser, M; Nguyen, B; Rodríguez, F; Rozas, I; Wilson, WD	1
Arai, C; Brun, R; Ge, JF; Ihara, M; Kaiser, M; Wittlin, S	1
Brun, R; Faist, J; Kaiser, M; Saf, R; Schlapper, C; Seebacher, W; Weis, R	2
Brun, R; Kehraus, S; König, GM; Krick, A; Pontius, A	1
Bakunov, SA; Bakunova, SM; Barszcz, T; Brun, R; Tidwell, RR; Wenzler, T; Werbovetz, KA	2
Alp, M; Brun, R; Göker, H; Yildiz, S	1
Bakunov, SA; Bakunova, SM; Barszcz, T; Bridges, AS; Brun, R; Jones, SK; Kumar, EV; Ohemeng, KA; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Baell, JB; Brun, R; Charman, WN; Fairlamb, AH; Holloway, GA; Kaiser, M; Kostewicz, E; Novello, PM; Parisot, JP; Richardson, J; Street, IP; Watson, KG	1
Bakunov, SA; Bakunova, SM; Barzcz, T; Brun, R; Chen, H; Jones, SK; Kumar, EV; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Bolognesi, ML; Bongarzone, S; Brun, R; Cavalli, A; Lizzi, F; Luise Krauth-Siegel, R	1
Brun, R; Dardonville, C; Fernández-Fernández, C; Gibbons, SL; Jagerovic, N; Kaiser, M; Nieto, L; Ryan, G	1
Büchold, C; Gelhaus, C; Gut, J; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Stempka, M	1
Brun, R; Cos, P; Dhooghe, L; Dommisse, R; Hajós, G; Hostyn, S; Kaiser, M; Lemière, G; Maes, BU; Maes, L; Mátyus, P; Nagy, I; Pieters, L; Riedl, Z; Tapolcsányi, P; Van Baelen, G	1
Brun, R; Franzblau, SG; Huang, Q; Kozikowski, AP; Mao, J; Wan, B; Wang, Y	1
Bakunov, SA; Bakunova, SM; Brun, R; Ghebru, M; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Brun, R; Lusvarghi, S; Mazzieri, MR; Pagliero, RJ; Pierini, AB	1
Breuning, A; Büchold, C; Degel, B; Gelhaus, C; Gut, J; Heppner, S; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rath, J; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Schulz, F; Stempka, M; Stich, A	1
Armstrong, T; Baell, JB; Holloway, GA; Novello, PM; Parisot, JP; Street, IP; Thompson, RC; Watson, KG	1
Amade, P; Cachet, N; Kaiser, M; Regalado, EL; Tasdemir, D; Thomas, OP	1
Baumann, K; Bischof, SK; Bringmann, G; Brun, R; Dreher, J; Gulder, T; Kaiser, M; Moll, H; Müller, S; Stich, A; Winter, C	1
Brun, R; Carballeira, NM; Herman, R; Kappe, SH; Lauinger, IL; Perozzo, R; Sanabria, D; Tarun, A; Tasdemir, D; Zloh, M	1
Bourguet-Kondracki, ML; Copp, BR; Finlayson, R; Harper, JL; Kaiser, M; Page, MJ; Pearce, AN; Webb, VL	1
Bauer, R; Brun, R; Gachet, MS; Kaiser, M; Keller, W; Kunert, O; Muñoz, RA; Schuehly, W; Zehl, M	1
Gerth, K; Jansen, R; Mohr, KI; Müller, R; Okanya, PW	1
Chan, ST; Copp, BR; Kaiser, M; Page, MJ; Pearce, AN	1
Brun, R; Ge, JF; Ihara, M; Kaiser, M; Liu, BQ; Shi, XL; Wittlin, S	1
Anizon, F; Bouchikhi, F; Brun, R; Moreau, P	1
Brun, R; Huang, TL; Kaiser, M; Mayence, A; Vanden Eynde, JJ; Yarlett, N	1
Brun, R; Faist, J; Kaiser, M; Saf, R; Seebacher, W; Weis, R	3
Dürüst, Y; Kaiser, M; Karakuş, H; Tasdemir, D	1
Boshoff, HI; Boyd, PD; Copp, BR; Kaiser, M; McCracken, ST	1
Bettis, S; Brun, R; Fomovska, A; Huang, Q; Kaiser, M; Kozikowski, AP; McLeod, R; Mui, E; Pieroni, M; Stec, J; Witola, WH	1
Copp, BR; Kaiser, M; Liew, LP	1
Gehrke, SS; Hider, RC; Pinto, EG; Pleban, K; Steverding, D; Tempone, AG; Wagner, GK	1
Kaiser, M; McKeever, C; Rozas, I	1
El Sayed, I; Inokuchi, T; Kaiser, M; Lu, WJ; Maeda, T; Mei, ZW; Pang, CQ; Peng, W; Wang, L	1
Arafa, RK; Boykin, DW; Brun, R; Ismail, MA; Jones, SK; Pandharkar, T; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA; Zhu, X	1
Almohaywi, B; Avery, VM; Baell, JB; Campbell, M; Charman, SA; Ferrins, L; Hyland, C; Jones, AJ; Kaiser, M; Rahmani, R; Ryan, E; Smith, J; Sykes, ML; Teston, E; White, KL; Yin, J	1
Bakunov, SA; Bakunova, SM; Barszcz, T; Boykin, DW; Brun, R; Jones, SK; Kumar, A; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Brun, R; Harel, D; Prinz, H; Schepmann, D; Schmidt, TJ; Wünsch, B	1
Bakunov, SA; Bakunova, SM; Brun, R; Patrick, DA; Tidwell, RR; Wenzler, T	1
Batzer, A; Bode, HB; Chantratita, N; Grundmann, F; Kaiser, M; Kurz, M; Schiell, M; Thanwisai, A	1
Dardonville, C; Kaiser, M; Lagartera, L; Ríos Martínez, CH	1
Botta, B; Brun, R; Costi, R; De Vita, D; Di Santo, R; Friggeri, L; Kaiser, M; Moraca, F; Scipione, L; Tortorella, S; Zamperini, C	1
Boykin, DW; Brun, R; Liu, ZY; Wenzler, T; Zhu, X	1
Avery, VM; Baell, JB; Bergström, CA; Charman, SA; Ferrins, L; Gazdik, M; Jones, AJ; Kaiser, M; Rahmani, R; Ryan, E; Sykes, ML; Varghese, S; White, KL	1
Bode, HB; Kaiser, M; Nollmann, FI; Reimer, D; Schultz, K	1
Ariën, KK; Augustyns, K; Cos, P; Dirié, B; Heeres, J; Joossens, J; Lewi, PJ; Lyssens, S; Maes, L; Michiels, J; Van der Veken, P; Vanham, G; Venkatraj, M	1
Battistuzzi, G; Giannini, G	1
Battistuzzi, G; Giannini, G; Vignola, D	1
Dardonville, C; Kaiser, M; Montalvo-Quirós, S; Taladriz-Sender, A	1
Brantner, A; Brun, R; Bucar, F; Faist, J; Gröblacher, B; Kaiser, M; Kalia, Y; Merino, V; Perozzo, R; Saf, R; Scapozza, L; Seebacher, W; Weis, R; Wolkinger, V	1
Brun, R; Göker, H; Kaiser, M; Karaaslan, C	1
Faist, J; Hinteregger, C; Kaiser, M; Mäser, P; Saf, R; Seebacher, W; Weis, R	1
Bringmann, G; Brun, R; Brünnert, D; Chatterjee, M; Efferth, T; Feineis, D; Kaiser, M; Li, J; Mudogo, V; Seo, EJ; Seupel, R	1
Back, TG; Brun, R; Kaiser, M; Manivannan, S; Pastor, A; Snyder, FF; Tran, HA; Wen, X; Zheng, Z	1
Brun, R; Kaiser, M; Mazzieri, MR; Nieto, MJ; Pagliero, RJ	1
Chianese, G; Erpenbeck, D; Kaiser, M; Luciano, P; Merten, C; Silber, J; Tasdemir, D; Topaloglu, B	1
Awale, S; Bringmann, G; Bruhn, T; Brun, R; Feineis, D; Kaiser, M; Li, J; Mudogo, V; Seupel, R	1
Alajlani, M; Bauer, R; Belaj, F; Brantner, A; Bucar, F; Faist, J; Hochegger, P; Kaiser, M; Kretschmer, N; Mäser, P; Mohsin, NU; Saf, R; Seebacher, W; Turek, I; Weis, R	1
Augustyns, K; Caljon, G; Heeres, J; Joossens, J; Lewi, PJ; Maes, L; Salado, IG; Van der Veken, P; Venkatraj, M	1
Bringmann, G; Brun, R; Efferth, T; Feineis, D; Kaiser, M; Mudogo, V; Seo, EJ; Tshitenge, DT	1
Aliabadi, A; De Mieri, M; Ebrahimi, SN; Farimani, MM; Hamburger, M; Kaiser, M; Khodaei, B; Moradi, H	1
Brun, R; Calvet, CM; Costi, R; De Leo, A; De Vita, D; Di Santo, R; Jennings, GK; Kaiser, M; Madia, VN; Mäser, P; Messore, A; Pescatori, L; Podust, LM; Saccoliti, F; Scipione, L; Tudino, V	1
Bode, HB; Cai, X; Kaiser, M; Zhao, L	1
Danton, O; Hamburger, M; Kaiser, M; Moridi Farimani, M; Nejad Ebrahimi, S; Neuburger, M; Potterat, O; Ramseyer, J; Salehi, P; Tabefam, M	1
Battista, MR; Brun, R; Calvet, CM; Cirilli, R; Costi, R; De Leo, A; De Vita, D; Di Marco, A; Di Santo, R; Faggi, C; Jennings, GK; Kaiser, M; Madia, VN; Mäser, P; Messore, A; Pepe, G; Pescatori, L; Podust, LM; Saccoliti, F; Scipione, L; Summa, V; Tudino, V	1
Awale, S; Bringmann, G; Bruhn, T; Brun, R; Feineis, D; Kaiser, M; Mudogo, V; Schmidt, D; Tshitenge, DT; Würthner, F	1
Buckner, FS; Cal, M; Davis, PH; Kaiser, M; Lepesheva, GI; Sanford, AG; Vennerstrom, JL; Wallick, AI; Wang, X	1
Al-Harrasi, A; Babanezhad Harikandei, K; Bararjanian, M; Ebrahimi, SN; Kaiser, M; Salehi, P	1
Awori, RM; Bode, HB; Groß, J; Kaiser, M; Opatz, T; Zhao, L	1
Bucar, F; Kaiser, M; Kalt, MM; Ochensberger, S; Presser, A; Saf, R; Schuehly, W; Solnier, J	1
Alajlani, M; Bauer, R; Belaj, F; Brantner, A; Dolensky, J; Hochegger, P; Kaiser, M; Kretschmer, N; Mäser, P; Mohsin, NU; Petritsch, M; Saf, R; Schühly, W; Seebacher, W; Weis, R	1
Bringmann, G; Feineis, D; Kaiser, M; Lombe, BK; Mudogo, V	1
Börgel, F; Jabor, VAP; Kaiser, M; Krauth-Siegel, RL; Lehmkuhl, K; Nonato, MC; Schepmann, D; Schmidt, TJ; Uth, JF; Wünsch, B	1
Brun, R; Celik, I; Doganc, F; Eren, G; Goker, H; Kaiser, M	1
Buyst, H	1
Poltera, AA	1
Barrett-Connor, E	1
Hochmann, A; Lambert, PH; Poltera, AA	1

Reviews

1 review(s) available for melarsoprol and chloroquine

Article	Year
Drugs for the treatment of parasitic infection. The Medical clinics of North America, 1982, Volume: 66, Issue:1 Topics: Antimony; Bithionol; Chloroquine; Diethylcarbamazine; Humans; Mebendazole; Melarsoprol; Metronidazole; Niclosamide; Niridazole; Oxamniquine; Parasitic Diseases; Pentamidine; Piperazines; Primaquine; Pyrantel Pamoate; Pyrimethamine; Suramin; Thiabendazole; Trichlorfon	1982

Other Studies

104 other study(ies) available for melarsoprol and chloroquine

Article	Year
Antimalarial, antitrypanosomal, and antileishmanial activities and cytotoxicity of bis(9-amino-6-chloro-2-methoxyacridines): influence of the linker. Journal of medicinal chemistry, 2000, Jul-13, Volume: 43, Issue:14 Topics: Acridines; Animals; Antimalarials; Cell Line; Leishmania infantum; Plasmodium falciparum; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi	2000
Pelorol from the tropical marine sponge Dactylospongia elegans. Journal of natural products, 2000, Volume: 63, Issue:8 Topics: Animals; Antiprotozoal Agents; Biological Assay; Chromatography, Gel; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Optical Rotation; Porifera; Queensland; Quinones; Sesquiterpenes; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet	2000
Ancistroealaines A and B, two new bioactive naphthylisoquinolines, and related naphthoic acids from Ancistrocladus ealaensis. Journal of natural products, 2000, Volume: 63, Issue:11 Topics: Animals; Antimalarials; Antiprotozoal Agents; Cell Line; Chromatography, High Pressure Liquid; Congo; Humans; Isoquinolines; Magnetic Resonance Spectroscopy; Mice; Plants, Medicinal; Rats; Trypanocidal Agents; Trypanosoma	2000
Lepadins D-F: antiplasmodial and antitrypanosomal decahydroquinoline derivatives from the tropical marine tunicate Didemnum sp. Journal of medicinal chemistry, 2002, Jul-04, Volume: 45, Issue:14 Topics: Alkaloids; Animals; Antimalarials; Antiparasitic Agents; Australia; Erythrocytes; Humans; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Quinolines; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Urochordata	2002
Ancistrotanzanine A, the first 5,3'-coupled naphthylisoquinoline alkaloid, and two further, 5,8'-linked related compounds from the newly described species Ancistrocladus tanzaniensis. Journal of natural products, 2003, Volume: 66, Issue:9 Topics: Alkaloids; Animals; Antiprotozoal Agents; Isoquinolines; Leishmania donovani; Magnoliopsida; Molecular Structure; Naphthalenes; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Stereoisomerism; Tanzania; Trypanosoma cruzi	2003
Ancistrotanzanine C and related 5,1'- and 7,3'-coupled naphthylisoquinoline alkaloids from Ancistrocladus tanzaniensis. Journal of natural products, 2004, Volume: 67, Issue:5 Topics: Alkaloids; Animals; Antimalarials; Isoquinolines; Leishmania donovani; Magnoliopsida; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Plants, Medicinal; Plasmodium falciparum; Tanzania; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2004
Ancistrobenomine a, the first naphthylisoquinoline oxygenated at Me-3, and related 5,1'-coupled alkaloids, from the "new" plant species ancistrocladusbenomensis. Journal of natural products, 2004, Volume: 67, Issue:12 Topics: Alkaloids; Animals; Antiprotozoal Agents; Isoquinolines; Leishmania donovani; Malaysia; Molecular Structure; Naphthalenes; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Plasmodium falciparum; Trypanosoma	2004
Ambigol C and 2,4-dichlorobenzoic acid, natural products produced by the terrestrial cyanobacterium Fischerella ambigua. Journal of natural products, 2005, Volume: 68, Issue:3 Topics: Animals; Antifungal Agents; Biphenyl Compounds; Carbazoles; Chlorobenzenes; Chlorobenzoates; Cyanobacteria; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenols; Switzerland; Trypanocidal Agents; Trypanosoma brucei rhodesiense	2005
Isoneocryptolepine, a synthetic indoloquinoline alkaloid, as an antiplasmodial lead compound. Journal of natural products, 2005, Volume: 68, Issue:5 Topics: Alkaloids; Animals; Antimalarials; Apocynaceae; Indole Alkaloids; Indoles; Molecular Structure; Plasmodium falciparum; Quinolines; Structure-Activity Relationship	2005
ent-Dioncophylleine A and related dehydrogenated naphthylisoquinoline alkaloids, the first Asian dioncophyllaceae-type alkaloids, from the "new"plant species Ancistrocladus benomensis. Journal of natural products, 2005, Volume: 68, Issue:5 Topics: Alkaloids; Animals; Antimalarials; Cells, Cultured; Isoquinolines; Malaysia; Molecular Structure; Naphthalenes; Plant Leaves; Plants, Medicinal; Plasmodium falciparum; Rats; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2005
Antiprotozoal activities of new bis-chlorophenyl derivatives of bicyclic octanes and aza-nonanes. Bioorganic & medicinal chemistry letters, 2006, Oct-15, Volume: 16, Issue:20 Topics: Animals; Antiprotozoal Agents; Bridged Bicyclo Compounds, Heterocyclic; In Vitro Techniques; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Stereoisomerism; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense	2006
Limonoid orthoacetates and antiprotozoal compounds from the roots of Pseudocedrela kotschyi. Journal of natural products, 2007, Volume: 70, Issue:1 Topics: Animals; Antiprotozoal Agents; Leishmania donovani; Limonins; Mali; Meliaceae; Molecular Structure; Plant Roots; Plants, Medicinal; Plasmodium falciparum; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2007
Bis-acridines as lead antiparasitic agents: structure-activity analysis of a discrete compound library in vitro. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Acridines; Animals; Antiparasitic Agents; Combinatorial Chemistry Techniques; Eukaryota; HL-60 Cells; Humans; Parasitic Sensitivity Tests; Plasmodium falciparum; Polyamines; Schistosoma mansoni; Structure-Activity Relationship; Trypanosoma brucei brucei	2007
Synthesis and in vitro antiprotozoal activities of dicationic 3,5-diphenylisoxazoles. Journal of medicinal chemistry, 2007, May-17, Volume: 50, Issue:10 Topics: Animals; Antimalarials; Benzamidines; Cations; Cell Line; Combinatorial Chemistry Techniques; Isoxazoles; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense	2007
Bicyclo[2.2.2]octyl esters of dialkylamino acids as antiprotozoals. Bioorganic & medicinal chemistry, 2007, Aug-15, Volume: 15, Issue:16 Topics: Alkylation; Amino Acids; Animals; Antiprotozoal Agents; Bridged Bicyclo Compounds; Esters; Inhibitory Concentration 50; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Trypanosoma brucei rhodesiense	2007
Epimers of bicyclo[2.2.2]octan-2-ol derivatives with antiprotozoal activity. European journal of medicinal chemistry, 2008, Volume: 43, Issue:4 Topics: Animals; Antiprotozoal Agents; Bridged Bicyclo Compounds; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrophotometry, Ultraviolet; Trypanosoma brucei brucei	2008
2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: Adenosine; Animals; Antimalarials; Dose-Response Relationship, Drug; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi	2007
Antiprotozoal polyacetylenes from the Tanzanian medicinal plant Cussonia zimmermannii. Journal of natural products, 2007, Volume: 70, Issue:10 Topics: Animals; Antiprotozoal Agents; Araliaceae; Leishmania donovani; Molecular Structure; Plants, Medicinal; Plasmodium falciparum; Polyynes; Tanzania; Trypanosoma brucei rhodesiense	2007
Synthesis and in vitro antiprotozoal activity of bisbenzofuran cations. Journal of medicinal chemistry, 2007, Nov-15, Volume: 50, Issue:23 Topics: Animals; Antimalarials; Benzofurans; Cations; Leishmania donovani; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense	2007
Synthesis and evaluation of antiparasitic activities of new 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine derivatives. Journal of medicinal chemistry, 2007, Nov-15, Volume: 50, Issue:23 Topics: Animals; Antimalarials; Leishmania donovani; Morpholines; Plasmodium falciparum; Pyrazoles; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma	2007
New bis(2-aminoimidazoline) and bisguanidine DNA minor groove binders with potent in vivo antitrypanosomal and antiplasmodial activity. Journal of medicinal chemistry, 2008, Feb-28, Volume: 51, Issue:4 Topics: Animals; Antimalarials; Cell Line; DNA; Female; Guanidines; Hemeproteins; Hemin; Imidazolines; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Rats; Structure-Activity Relationship; Transition Temperature; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2008
Synthesis and in vitro antiprotozoal activities of water-soluble, inexpensive 3,7-bis(dialkylamino)phenoxazin-5-ium derivatives. Journal of medicinal chemistry, 2008, Jun-26, Volume: 51, Issue:12 Topics: Animals; Antimalarials; Antiprotozoal Agents; Chloroquine; Drug Resistance; Leishmania donovani; Oxazines; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2008
Novel azabicyclo[3.2.2]nonane derivatives and their activities against Plasmodium falciparum K1 and Trypanosoma brucei rhodesiense. Bioorganic & medicinal chemistry, 2008, Jun-15, Volume: 16, Issue:12 Topics: Animals; Antimalarials; Azabicyclo Compounds; Plasmodium falciparum; Trypanocidal Agents; Trypanosoma brucei brucei	2008
Antiplasmodial and antitrypanosomal activities of aminobicyclo[2.2.2]octyl omega-aminoalkanoates. European journal of medicinal chemistry, 2009, Volume: 44, Issue:2 Topics: Animals; Antiprotozoal Agents; Bridged Bicyclo Compounds; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense	2009
Antiprotozoal activities of heterocyclic-substituted xanthones from the marine-derived fungus Chaetomium sp. Journal of natural products, 2008, Volume: 71, Issue:9 Topics: Animals; Antiprotozoal Agents; Bacillus megaterium; Chaetomium; Chlorella; Drug Screening Assays, Antitumor; Escherichia coli; Leishmania donovani; Marine Biology; Microbial Sensitivity Tests; Models, Molecular; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Trypanosoma cruzi; Xanthones	2008
Synthesis and antiprotozoal activity of cationic 2-phenylbenzofurans. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Animals; Antiprotozoal Agents; Benzofurans; Cations; Disease Models, Animal; Leishmania; Mice; Molecular Structure; Structure-Activity Relationship; Trypanosoma; Trypanosomiasis	2008
Synthesis and antiparasitic and antifungal evaluation of 2'-arylsubstituted-1H,1'H-[2,5']bisbenzimidazolyl-5-carboxamidines. European journal of medicinal chemistry, 2009, Volume: 44, Issue:5 Topics: Amidines; Animals; Antifungal Agents; Antiparasitic Agents; Leishmania donovani; Microbial Sensitivity Tests; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma cruzi	2009
Structure-activity study of pentamidine analogues as antiprotozoal agents. Journal of medicinal chemistry, 2009, Apr-09, Volume: 52, Issue:7 Topics: Animals; Antimalarials; Cadaverine; Drug Resistance; Female; Imidazoles; Leishmania donovani; Mice; Myoblasts; Parasitic Sensitivity Tests; Pentamidine; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis	2009
Trypanothione reductase high-throughput screening campaign identifies novel classes of inhibitors with antiparasitic activity. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7 Topics: Animals; Antiparasitic Agents; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Molecular Structure; NADH, NADPH Oxidoreductases; Structure-Activity Relationship; Trypanosoma; Trypanosomiasis	2009
Antiplasmodial and antitrypanosomal activity of bicyclic amides and esters of dialkylamino acids. Bioorganic & medicinal chemistry, 2009, May-15, Volume: 17, Issue:10 Topics: Amides; Amino Acids; Animals; Antimalarials; Bridged Bicyclo Compounds; Esters; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense	2009
Synthesis and antiprotozoal activities of dicationic bis(phenoxymethyl)benzenes, bis(phenoxymethyl)naphthalenes, and bis(benzyloxy)naphthalenes. European journal of medicinal chemistry, 2009, Volume: 44, Issue:9 Topics: Animals; Antiprotozoal Agents; Benzene; Cell Survival; Leishmania donovani; Mice; Myoblasts; Naphthalenes; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2009
Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase. Bioorganic & medicinal chemistry letters, 2009, Jun-01, Volume: 19, Issue:11 Topics: Animals; Antiparasitic Agents; Cell Line; Computer Simulation; Drug Design; Enzyme Inhibitors; Glutathione Reductase; Humans; NADH, NADPH Oxidoreductases; Quinazolines; Rats; Structure-Activity Relationship; Trypanosoma cruzi	2009
Antiprotozoal activity of 1-phenethyl-4-aminopiperidine derivatives. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9 Topics: Animals; Antiprotozoal Agents; Cell Line; Eukaryota; Female; Inhibitory Concentration 50; Leishmania donovani; Mice; Molecular Structure; Parasitic Sensitivity Tests; Piperidines; Plasmodium falciparum; Rats; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2009
Synthesis and antiprotozoal activity of pyridyl analogues of pentamidine. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Animals; Antiprotozoal Agents; Female; Leishmania donovani; Mice; Pentamidine; Plasmodium falciparum; Pyridines; Rats; Structure-Activity Relationship	2009
On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences. Journal of medicinal chemistry, 2009, Sep-24, Volume: 52, Issue:18 Topics: Amino Acid Sequence; Animals; Antiprotozoal Agents; Cathepsin L; Cathepsins; Cattle; Combinatorial Chemistry Techniques; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diamide; Drug Evaluation, Preclinical; Fumarates; Humans; Peptide Library; Plasmodium falciparum	2009
Structure-activity relationship of antiparasitic and cytotoxic indoloquinoline alkaloids, and their tricyclic and bicyclic analogues. Bioorganic & medicinal chemistry, 2009, Oct-15, Volume: 17, Issue:20 Topics: Animals; Antimalarials; Antineoplastic Agents; Indole Alkaloids; Mice; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship	2009
Searching for new cures for tuberculosis: design, synthesis, and biological evaluation of 2-methylbenzothiazoles. Journal of medicinal chemistry, 2009, Nov-12, Volume: 52, Issue:21 Topics: Antimalarials; Antitubercular Agents; Benzothiazoles; Drug Design; Isoxazoles; Models, Molecular; Mycobacterium tuberculosis; Phenylacetates; Stereoisomerism; Structure-Activity Relationship; Trypanocidal Agents	2009
Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1H-1,2,3-triazoles. Journal of medicinal chemistry, 2010, Jan-14, Volume: 53, Issue:1 Topics: Amidines; Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Disease Models, Animal; Female; Leishmania donovani; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Stereoisomerism; Structure-Activity Relationship; Triazoles; Trypanosoma brucei rhodesiense	2010
Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines. Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1 Topics: Animals; Antiprotozoal Agents; Cell Line; Humans; Leishmania donovani; Models, Molecular; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Infections; Quinolines; Structure-Activity Relationship; Trypanosoma; Trypanosoma cruzi	2010
Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids. Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5 Topics: Antimalarials; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei	2010
Discovery of novel and potent benzhydryl-tropane trypanocides highly selective for Trypanosoma cruzi. Bioorganic & medicinal chemistry letters, 2010, Mar-15, Volume: 20, Issue:6 Topics: Animals; Cell Line; Drug Discovery; Rats; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi	2010
Antiprotozoal steroidal saponins from the marine sponge Pandaros acanthifolium. Journal of natural products, 2010, Aug-27, Volume: 73, Issue:8 Topics: Animals; Antiprotozoal Agents; Leishmania donovani; Marine Biology; Nuclear Magnetic Resonance, Biomolecular; Oceans and Seas; Plasmodium falciparum; Porifera; Saponins; Steroids; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2010
QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids. European journal of medicinal chemistry, 2010, Volume: 45, Issue:11 Topics: Alkaloids; Animals; Antimalarials; Isoquinolines; Magnetic Resonance Spectroscopy; Models, Molecular; Plasmodium falciparum; Quantitative Structure-Activity Relationship; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared	2010
2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections. Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21 Topics: Alkynes; Antimalarials; Binding Sites; Cell Line, Tumor; Computer Simulation; Erythrocytes; Fatty Acid Synthase, Type II; Fatty Acids, Unsaturated; Humans; Kinetics; Liver; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins	2010
Didemnidines A and B, indole spermidine alkaloids from the New Zealand ascidian Didemnum sp. Journal of natural products, 2011, Apr-25, Volume: 74, Issue:4 Topics: Animals; Antiprotozoal Agents; Indole Alkaloids; Leishmania donovani; Molecular Structure; New Zealand; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Spermidine; Structure-Activity Relationship; Trypanosoma; Urochordata	2011
Antiparasitic compounds from Cupania cinerea with activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense. Journal of natural products, 2011, Apr-25, Volume: 74, Issue:4 Topics: Animals; Antiprotozoal Agents; Cells, Cultured; Crystallography, X-Ray; Diterpenes; Ecuador; Glycosides; Hexanes; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Polycyclic Sesquiterpenes; Rats; Sapindaceae; Sesquiterpenes; Triterpenes; Trypanosoma brucei rhodesiense	2011
Marinoquinolines A-F, pyrroloquinolines from Ohtaekwangia kribbensis (Bacteroidetes). Journal of natural products, 2011, Apr-25, Volume: 74, Issue:4 Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Antineoplastic Agents; Bacteroidetes; Drug Screening Assays, Antitumor; Female; Humans; India; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Pyrroles; Quinolines	2011
Antimalarial β-carbolines from the New Zealand ascidian Pseudodistoma opacum. Journal of natural products, 2011, Sep-23, Volume: 74, Issue:9 Topics: Animals; Antimalarials; Carbolines; Chloroquine; Drug Resistance; Molecular Structure; New Zealand; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Stereoisomerism; Urochordata	2011
Synthesis and in vitro antiprotozoal activities of 5-phenyliminobenzo[a]phenoxazine derivatives. Bioorganic & medicinal chemistry letters, 2011, Oct-01, Volume: 21, Issue:19 Topics: Animals; Antimalarials; Antiprotozoal Agents; Drug Design; Inhibitory Concentration 50; Leishmania donovani; Malaria; Models, Chemical; Molecular Structure; Myoblasts; Oxazines; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyridinium Compounds; Rats; Structure-Activity Relationship; Thiazoles; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2011
Biological evaluation of glycosyl-isoindigo derivatives against the pathogenic agents of tropical diseases (malaria, Chagas disease, leishmaniasis and human African trypanosomiasis). Bioorganic & medicinal chemistry letters, 2011, Nov-01, Volume: 21, Issue:21 Topics: Animals; Antiprotozoal Agents; Drug Evaluation, Preclinical; Humans; Protozoan Infections	2011
Bis(oxyphenylene)benzimidazoles: a novel class of anti-Plasmodium falciparum agents. Bioorganic & medicinal chemistry, 2011, Dec-15, Volume: 19, Issue:24 Topics: Animals; Antimalarials; Benzimidazoles; Cell Line; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats	2011
New N-methylpiperazinyl derivatives of bicyclic antiprotozoal compounds. European journal of medicinal chemistry, 2012, Volume: 47, Issue:1 Topics: Animals; Antiprotozoal Agents; Bridged Bicyclo Compounds; Inhibitory Concentration 50; Male; Mice; Piperazine; Piperazines; Plasmodium falciparum; Trypanosoma brucei rhodesiense	2012
Synthesis and anti-protozoal activity of novel dihydropyrrolo[3,4-d][1,2,3]triazoles. European journal of medicinal chemistry, 2012, Volume: 48 Topics: Animals; Antiprotozoal Agents; Cell Line; Eukaryota; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Molecular Structure; Oxadiazoles; Protozoan Infections; Pyrroles; Rats; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Triazoles	2012
Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimers. Bioorganic & medicinal chemistry, 2012, Feb-15, Volume: 20, Issue:4 Topics: Antimalarials; Antitubercular Agents; Coumarins; Dimerization; Fatty Acids, Monounsaturated; Inhibitory Concentration 50; Leishmania donovani; Light; Molecular Structure; Plasmodium falciparum; Pyrones	2012
Synthesis, biological evaluation, and structure-activity relationships of N-benzoyl-2-hydroxybenzamides as agents active against P. falciparum (K1 strain), Trypanosomes, and Leishmania. Journal of medicinal chemistry, 2012, Apr-12, Volume: 55, Issue:7 Topics: Antimalarials; Benzamides; Imides; Leishmania donovani; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2012
Discovery and preliminary structure-activity relationship analysis of 1,14-sperminediphenylacetamides as potent and selective antimalarial lead compounds. Bioorganic & medicinal chemistry letters, 2013, Jan-15, Volume: 23, Issue:2 Topics: Acetamides; Animals; Antimalarials; Drug Discovery; Inhibitory Concentration 50; Malaria; Molecular Structure; Plasmodium falciparum; Spermine; Structure-Activity Relationship	2013
Conjugation to 4-aminoquinoline improves the anti-trypanosomal activity of Deferiprone-type iron chelators. Bioorganic & medicinal chemistry, 2013, Feb-01, Volume: 21, Issue:3 Topics: Aminoquinolines; Antiprotozoal Agents; Deferiprone; Dose-Response Relationship, Drug; Iron Chelating Agents; Leishmania infantum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyridones; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma cruzi	2013
Aminoalkyl derivatives of guanidine diaromatic minor groove binders with antiprotozoal activity. Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3 Topics: Animals; Antiprotozoal Agents; Guanidine; Nucleic Acid Denaturation; Plasmodium falciparum; Trypanosoma brucei rhodesiense	2013
Synthesis and in vitro antimalarial testing of neocryptolepines: SAR study for improved activity by introduction and modifications of side chains at C2 and C11 on indolo[2,3-b]quinolines. Journal of medicinal chemistry, 2013, Feb-28, Volume: 56, Issue:4 Topics: Alkaloids; Animals; Antimalarials; Cell Line; Chloroquine; Drug Resistance; Indoles; Malaria; Mice; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Quinolines; Rats; Structure-Activity Relationship	2013
Synthesis and antiprotozoal activity of dicationic m-terphenyl and 1,3-dipyridylbenzene derivatives. Journal of medicinal chemistry, 2013, Jul-11, Volume: 56, Issue:13 Topics: Animals; Antiprotozoal Agents; Benzene; Chagas Disease; Female; Leishmania donovani; Mice; Mice, Inbred Strains; Models, Chemical; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyridines; Structure-Activity Relationship; Terphenyl Compounds; Trypanosoma cruzi	2013
3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis. European journal of medicinal chemistry, 2013, Volume: 66 Topics: Anilides; Animals; Humans; Mice; Myoblasts, Skeletal; Rats; Species Specificity; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2013
Synthesis and antiprotozoal activities of benzyl phenyl ether diamidine derivatives. European journal of medicinal chemistry, 2013, Volume: 67 Topics: Animals; Antiprotozoal Agents; Dose-Response Relationship, Drug; Leishmania donovani; Mice; Molecular Structure; Myoblasts; Parasitic Sensitivity Tests; Pentamidine; Phenyl Ethers; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis	2013
Antiprotozoal activity of bicyclic diamines with a N-methylpiperazinyl group at the bridgehead atom. Bioorganic & medicinal chemistry, 2013, Sep-01, Volume: 21, Issue:17 Topics: Animals; Antiprotozoal Agents; Bridged Bicyclo Compounds; Cell Line; Cell Survival; Disease Models, Animal; Female; Mice; Parasitic Sensitivity Tests; Piperazine; Piperazines; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense	2013
Natural product derived antiprotozoal agents: synthesis, biological evaluation, and structure-activity relationships of novel chromene and chromane derivatives. Journal of medicinal chemistry, 2013, Sep-26, Volume: 56, Issue:18 Topics: Antiprotozoal Agents; Biological Products; Chemistry Techniques, Synthetic; Chromans; Inhibitory Concentration 50; Structure-Activity Relationship	2013
Antiprotozoal activity of dicationic 3,5-diphenylisoxazoles, their prodrugs and aza-analogues. Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1 Topics: Animals; Antiprotozoal Agents; Isoxazoles; Mice; Molecular Structure; Plasmodium falciparum; Prodrugs; Structure-Activity Relationship; Trypanosomiasis, African	2014
Antiparasitic chaiyaphumines from entomopathogenic Xenorhabdus sp. PB61.4. Journal of natural products, 2014, Apr-25, Volume: 77, Issue:4 Topics: Animals; Antiparasitic Agents; Bacillus subtilis; Depsipeptides; Escherichia coli; Humans; Inhibitory Concentration 50; Micrococcus luteus; Molecular Structure; Nematoda; Nuclear Magnetic Resonance, Biomolecular; Parasitic Sensitivity Tests; Plasmodium falciparum; Saccharomyces cerevisiae; Thailand; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Xenorhabdus	2014
Antiprotozoal activity and DNA binding of N-substituted N-phenylbenzamide and 1,3-diphenylurea bisguanidines. European journal of medicinal chemistry, 2014, Jun-23, Volume: 81 Topics: Animals; Antiparasitic Agents; Benzamides; Binding Sites; Cell Line; Cell Survival; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Female; Guanidines; Mice; Mice, Inbred Strains; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Surface Plasmon Resonance; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Urea	2014
New Promising Compounds with in Vitro Nanomolar Activity against Trypanosoma cruzi. ACS medicinal chemistry letters, 2013, Jun-13, Volume: 4, Issue:6 Topics:	2013
Synthesis and antiparasitic activity of new bis-arylimidamides: DB766 analogs modified in the terminal groups. European journal of medicinal chemistry, 2014, Aug-18, Volume: 83 Topics: Amides; Animals; Antiparasitic Agents; Cell Line; Chemistry Techniques, Synthetic; Leishmania; Plasmodium falciparum; Rats; Trypanosoma	2014
Pyridyl benzamides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei. Journal of medicinal chemistry, 2014, Aug-14, Volume: 57, Issue:15 Topics: Animals; Benzamides; Cell Line; HEK293 Cells; Humans; Microsomes, Liver; Myoblasts; Pyridines; Rats; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense	2014
Xenortide Biosynthesis by Entomopathogenic Xenorhabdus nematophila. Journal of natural products, 2014, Aug-22, Volume: 77, Issue:8 Topics: Chromatography, High Pressure Liquid; Dipeptides; Leishmania; Molecular Structure; Multigene Family; Nuclear Magnetic Resonance, Biomolecular; Parasitic Sensitivity Tests; Plasmodium falciparum; Trypanosoma brucei brucei; Tryptamines; Xenorhabdus	2014
From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds. Bioorganic & medicinal chemistry, 2014, Oct-01, Volume: 22, Issue:19 Topics: Anti-HIV Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense	2014
Exploring in vitro and in vivo Hsp90 inhibitors activity against human protozoan parasites. Bioorganic & medicinal chemistry letters, 2015, Feb-01, Volume: 25, Issue:3 Topics: Animals; Antiprotozoal Agents; Cell Line, Tumor; Disease Models, Animal; HSP90 Heat-Shock Proteins; Humans; Mice; Parasitemia; Plasmodium falciparum; Protein Binding; Rats; Triazoles; Trypanosoma brucei rhodesiense	2015
Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite. Bioorganic & medicinal chemistry letters, 2015, Feb-01, Volume: 25, Issue:3 Topics: Animals; Antimalarials; Cell Line, Tumor; Dipeptides; Disease Models, Animal; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Malaria; Mice; Parasites; Plasmodium falciparum; Protein Isoforms	2015
Antiprotozoal activity and DNA binding of dicationic acridones. Journal of medicinal chemistry, 2015, Feb-26, Volume: 58, Issue:4 Topics: Acridines; Acridones; Antiprotozoal Agents; Binding Sites; Cations; DNA; Dose-Response Relationship, Drug; Leishmania donovani; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2015
Synthesis of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities. Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7 Topics: Administration, Oral; Animals; Antiprotozoal Agents; Azabicyclo Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Rats; Structure-Activity Relationship; Tissue Distribution; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2015
Antiprotozoal activity of bicycles featuring a dimethylamino group at their bridgehead. Bioorganic & medicinal chemistry, 2016, 08-15, Volume: 24, Issue:16 Topics: Animals; Antiprotozoal Agents; Bridged Bicyclo Compounds; Cells, Cultured; Plasmodium falciparum; Rats; Spectrum Analysis; Structure-Activity Relationship; Trypanosoma brucei rhodesiense	2016
Synthesis and potent antiprotozoal activity of mono/di amidino 2-anilinobenzimidazoles versus Plasmodium falciparum and Trypanosoma brucei rhodesiense. Bioorganic & medicinal chemistry, 2016, 09-15, Volume: 24, Issue:18 Topics: Aniline Compounds; Animals; Antiprotozoal Agents; Benzimidazoles; Cell Line; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2016
New derivatives of 7-chloroquinolin-4-amine with antiprotozoal activity. Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3 Topics: Aminoquinolines; Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense	2017
Dioncophyllines C Journal of natural products, 2017, 02-24, Volume: 80, Issue:2 Topics: Alkaloids; Antimalarials; Antineoplastic Agents; Humans; Isoquinolines; Magnoliopsida; Molecular Structure; Multiple Myeloma; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Structure-Activity Relationship	2017
Synthesis and activity of nucleoside-based antiprotozoan compounds. Bioorganic & medicinal chemistry, 2017, 04-01, Volume: 25, Issue:7 Topics: Animals; Antiprotozoal Agents; Carbon-13 Magnetic Resonance Spectroscopy; Inhibitory Concentration 50; Leishmania donovani; Plasmodium falciparum; Proton Magnetic Resonance Spectroscopy; Spectrophotometry, Infrared; Trypanosoma brucei brucei; Trypanosoma cruzi	2017
Lead selection of antiparasitic compounds from a focused library of benzenesulfonyl derivatives of heterocycles. Bioorganic & medicinal chemistry letters, 2017, 09-01, Volume: 27, Issue:17 Topics: Animals; Antiparasitic Agents; Benzyl Compounds; Dose-Response Relationship, Drug; Heterocyclic Compounds; Leishmania donovani; Molecular Structure; Myoblasts; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2017
Antiprotozoal Linear Furanosesterterpenoids from the Marine Sponge Ircinia oros. Journal of natural products, 2017, 09-22, Volume: 80, Issue:9 Topics: Animals; Antiprotozoal Agents; Furans; Magnetic Resonance Spectroscopy; Molecular Structure; Porifera; Sesquiterpenes; Spectroscopy, Fourier Transform Infrared	2017
Jozilebomines A and B, Naphthylisoquinoline Dimers from the Congolese Liana Ancistrocladus ileboensis, with Antiausterity Activities against the PANC-1 Human Pancreatic Cancer Cell Line. Journal of natural products, 2017, 10-27, Volume: 80, Issue:10 Topics: Algorithms; Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Congo; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Isoquinolines; Leishmania donovani; Magnoliopsida; Molecular Structure; Naphthalenes; Nuclear Magnetic Resonance, Biomolecular; Pancreatic Neoplasms; Plasmodium falciparum; Rats; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Tumor Cells, Cultured	2017
Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. European journal of medicinal chemistry, 2018, Jan-01, Volume: 143 Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Antiprotozoal Agents; Bacteria; Benzyl Compounds; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyridines; Quaternary Ammonium Compounds; Rats; Saccharomyces cerevisiae; Salts; Structure-Activity Relationship; Trypanosoma brucei rhodesiense	2018
Novel triazine dimers with potent antitrypanosomal activity. European journal of medicinal chemistry, 2018, Jan-01, Volume: 143 Topics: Animals; Antiprotozoal Agents; Cell Proliferation; Cell Survival; Dimerization; Dose-Response Relationship, Drug; Drug Discovery; Fibroblasts; Humans; Leishmania infantum; Male; Mice; Molecular Structure; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazines; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2018
Mbandakamine-Type Naphthylisoquinoline Dimers and Related Alkaloids from the Central African Liana Ancistrocladus ealaensis with Antiparasitic and Antileukemic Activities. Journal of natural products, 2018, 04-27, Volume: 81, Issue:4 Topics: Africa, Central; Alkaloids; Antimalarials; Antineoplastic Agents, Phytogenic; Antiparasitic Agents; Caryophyllales; Cell Line, Tumor; Humans; Isoquinolines; Naphthalenes; Plasmodium falciparum; Quinolines	2018
Phytochemical Study of Salvia leriifolia Roots: Rearranged Abietane Diterpenoids with Antiprotozoal Activity. Journal of natural products, 2018, 06-22, Volume: 81, Issue:6 Topics: Abietanes; Antimalarials; Antiprotozoal Agents; Inhibitory Concentration 50; Leishmania donovani; Parasitic Sensitivity Tests; Phytochemicals; Plant Extracts; Plant Roots; Plasmodium falciparum; Salvia; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2018
Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents. European journal of medicinal chemistry, 2018, Aug-05, Volume: 156 Topics: Animals; Antiprotozoal Agents; Cell Line; Chagas Disease; Female; Humans; Imidazoles; Inhibitory Concentration 50; Leishmania donovani; Leishmaniasis, Visceral; Malaria, Falciparum; Mice; Mice, Inbred BALB C; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Trypanosomiasis, African	2018
Methionine-Containing Rhabdopeptide/Xenortide-like Peptides from Heterologous Expression of the Biosynthetic Gene Cluster kj12ABC in Escherichia coli. Journal of natural products, 2018, 10-26, Volume: 81, Issue:10 Topics: Amino Acids; Animals; Antineoplastic Agents; Antiparasitic Agents; Escherichia coli; Methionine; Multigene Family; Oligopeptides; Parasites; Rats; Xenorhabdus	2018
Antiprotozoal Isoprenoids from Salvia hydrangea. Journal of natural products, 2018, 12-28, Volume: 81, Issue:12 Topics: Animals; Antiprotozoal Agents; Cell Line; Leishmania donovani; Magnetic Resonance Spectroscopy; Molecular Structure; Plasmodium falciparum; Rats; Salvia; Spectrum Analysis; Terpenes; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2018
Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents. Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3 Topics: Animals; Antiprotozoal Agents; Cytochrome P-450 Enzyme Inhibitors; Drug Design; Drug Evaluation, Preclinical; Humans; Imidazoles; Parasitic Sensitivity Tests; Trypanosoma	2019
Ealamines A-H, a Series of Naphthylisoquinolines with the Rare 7,8'-Coupling Site, from the Congolese Liana Journal of natural products, 2019, 11-22, Volume: 82, Issue:11 Topics: Animals; Antineoplastic Agents, Phytogenic; Antiprotozoal Agents; Caryophyllales; Drug Screening Assays, Antitumor; Humans; Isoquinolines; Leishmania; Molecular Structure; Naphthalenes; Pancreatic Neoplasms; Plant Components, Aerial; Plant Leaves; Plasmodium; Rats; Trypanosoma	2019
A new chemotype with promise against Trypanosoma cruzi. Bioorganic & medicinal chemistry letters, 2020, 01-01, Volume: 30, Issue:1 Topics: Animals; Chagas Disease; Humans; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi	2020
Synthesis, in-vitro antiprotozoal activity and molecular docking study of isothiocyanate derivatives. Bioorganic & medicinal chemistry, 2020, 01-01, Volume: 28, Issue:1 Topics: Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Isothiocyanates; Leishmania donovani; Molecular Docking Simulation; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2020
Structure, Biosynthesis, and Bioactivity of Photoditritide from Journal of natural products, 2019, 12-27, Volume: 82, Issue:12 Topics: Anti-Bacterial Agents; Antiprotozoal Agents; Microbial Sensitivity Tests; Micrococcus luteus; Molecular Structure; Photorhabdus; Spectrum Analysis; Trypanosoma brucei rhodesiense	2019
Palladium-catalysed synthesis of arylnaphthoquinones as antiprotozoal and antimycobacterial agents. European journal of medicinal chemistry, 2020, Dec-01, Volume: 207 Topics: Anti-Bacterial Agents; Antiprotozoal Agents; Catalysis; Chemistry Techniques, Synthetic; Mycobacterium smegmatis; Palladium; Plasmodium falciparum; Quinones; Trypanosoma brucei rhodesiense	2020
Preparation of new 1,3-dibenzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. European journal of medicinal chemistry, 2021, Jan-15, Volume: 210 Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Antineoplastic Agents; Candida albicans; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Epidermis; Escherichia coli; Female; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pseudomonas aeruginosa; Quaternary Ammonium Compounds; Rats; Salts; Staphylococcus aureus; Structure-Activity Relationship	2021
Spirombandakamine A Journal of natural products, 2021, 04-23, Volume: 84, Issue:4 Topics: Alkaloids; Animals; Antiprotozoal Agents; Caryophyllales; Cell Line; Democratic Republic of the Congo; Isoquinolines; Molecular Structure; Phytochemicals; Plant Leaves; Plasmodium falciparum; Rats; Trypanosoma brucei rhodesiense	2021
Synthesis and Biological Evaluation of Natural-Product-Inspired, Aminoalkyl-Substituted 1-Benzopyrans as Novel Antiplasmodial Agents. Journal of medicinal chemistry, 2021, 05-13, Volume: 64, Issue:9 Topics: Alkylation; Animals; Antimalarials; Benzopyrans; Biological Products; Biomimetic Materials; Chemistry Techniques, Synthetic; Erythrocytes; Kinetics; Mice; Plasmodium; Structure-Activity Relationship	2021
Synthesis, in vitro antiprotozoal activity, molecular docking and molecular dynamics studies of some new monocationic guanidinobenzimidazoles. European journal of medicinal chemistry, 2021, Oct-05, Volume: 221 Topics: Antiprotozoal Agents; Benzimidazoles; Cations; Dose-Response Relationship, Drug; Guanidine; Leishmania donovani; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2021
The treatment of T. rhodesiense sleeping sickness, with special reference to its physio-pathological and epidemiological basis. Annales de la Societe belge de medecine tropicale, 1975, Volume: 55, Issue:2 Topics: Arsenicals; Chloroquine; Humans; Melarsoprol; Proguanil; Suramin; Trypanosomiasis, African; Zambia	1975
Chemotherapy, relapses and CNS in experimental African trypanosomiasis. Contributions to microbiology and immunology, 1983, Volume: 7 Topics: Animals; Central Nervous System; Chlorocebus aethiops; Chloroquine; Melarsoprol; Mice; Recurrence; Trypanosoma brucei brucei; Trypanosomiasis, African	1983
Trypanosoma brucei brucei: the response to Melarsoprol in mice with cerebral trypanosomiasis. An immunopathological study. Clinical and experimental immunology, 1981, Volume: 46, Issue:2 Topics: Animals; Antigen-Antibody Complex; Arsenicals; Brain; Brain Diseases; Chloroquine; Fluorescent Antibody Technique; Injections, Intraperitoneal; Injections, Intravenous; Melarsoprol; Mice; Nitroimidazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1981