Page last updated: 2024-09-05

melagatran and ticlopidine

melagatran has been researched along with ticlopidine in 4 studies

Compound Research Comparison

Studies
(melagatran)
Trials
(melagatran)
Recent Studies (post-2010)
(melagatran)
Studies
(ticlopidine)
Trials
(ticlopidine)
Recent Studies (post-2010) (ticlopidine)
185321910,2891,8934,671

Protein Interaction Comparison

ProteinTaxonomymelagatran (IC50)ticlopidine (IC50)
Alpha-2A adrenergic receptorHomo sapiens (human)0.382
Cytochrome P450 2D6Homo sapiens (human)6.2928
Alpha-2B adrenergic receptorHomo sapiens (human)0.304
Alpha-2C adrenergic receptorHomo sapiens (human)1.175
Cytochrome P450 2B6Homo sapiens (human)0.405
Cytochrome P450 2C19Homo sapiens (human)0.6678
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.426

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Braunwald, E; Giugliano, RP1
Driscoll, E; Hong, TT; Huang, J; Lucchesi, BR1
Meyer Samama, M1
Badimon, JJ; Bylock, A; Elg, M; Eriksson, UG; Eriksson-Lepkowska, M; Kalies, I; Nyström, P; Sarich, TC; Wåhlander, K1

Reviews

1 review(s) available for melagatran and ticlopidine

ArticleYear
[The new antithrombotic agents].
    Presse medicale (Paris, France : 1983), 2005, Oct-22, Volume: 34, Issue:18

    Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Azetidines; Benzylamines; Clopidogrel; Fibrinolytic Agents; Glycine; Hirudins; Humans; Injections, Subcutaneous; Platelet Aggregation Inhibitors; Polysaccharides; Prodrugs; Randomized Controlled Trials as Topic; Stents; Thrombosis; Ticlopidine; Time Factors; Venous Thrombosis

2005

Trials

1 trial(s) available for melagatran and ticlopidine

ArticleYear
Antithrombotic effects of ximelagatran plus acetylsalicylic acid (ASA) and clopidogrel plus ASA in a human ex vivo arterial thrombosis model.
    Thrombosis and haemostasis, 2006, Volume: 95, Issue:3

    Topics: Administration, Oral; Adult; Anticoagulants; Arteries; Aspirin; Azetidines; Benzylamines; Bleeding Time; Blood Coagulation; Clopidogrel; Dose-Response Relationship, Drug; Fibrinolytic Agents; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin; Thrombosis; Ticlopidine

2006

Other Studies

2 other study(ies) available for melagatran and ticlopidine

ArticleYear
Improving antithrombotic treatment in patients after myocardial infarction.
    Lancet (London, England), 2003, Sep-06, Volume: 362, Issue:9386

    Topics: Azetidines; Benzylamines; Clopidogrel; Fibrinolytic Agents; Glycine; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome; Warfarin

2003
The antithrombotic effect of melagatran in combination with clopidogrel and/or aspirin (carotid artery primary thrombosis study).
    Journal of cardiovascular pharmacology, 2005, Volume: 46, Issue:4

    Topics: Animals; Aspirin; Azetidines; Benzylamines; Bleeding Time; Blood Flow Velocity; Blood Pressure; Carotid Artery Thrombosis; Carotid Artery, Common; Clopidogrel; Disease Models, Animal; Dogs; Drug Therapy, Combination; Female; Fibrinolytic Agents; Heart Rate; Male; Partial Thromboplastin Time; Platelet Aggregation; Platelet Aggregation Inhibitors; Random Allocation; Ticlopidine; Tongue; Vascular Patency

2005