melagatran has been researched along with thromboplastin in 12 studies
| Studies (melagatran) | Trials (melagatran) | Recent Studies (post-2010) (melagatran) | Studies (thromboplastin) | Trials (thromboplastin) | Recent Studies (post-2010) (thromboplastin) |
|---|---|---|---|---|---|
| 185 | 32 | 19 | 10,540 | 281 | 2,126 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (66.67) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lindahl, TL; Mattsson, C; Menschiek-Lundin, A; Wåhlander, K | 1 |
| Marder, VJ | 1 |
| Cvirn, G; Gallistl, S; Koestenberger, M; Leschnik, B; Muntean, W; Rehak, T; Roschitz, B | 1 |
| Furugohri, T; Honda, Y; Isobe, K; Matsumoto, C; Muramatsu, S; Shiozaki, Y; Sugiyama, N | 1 |
| Cvirn, G; Fritsch, P; Gallistl, S; Koestenberger, M; Leschnik, B; Muntean, W | 1 |
| Craven, S; Dewar, L; Greinacher, A; Ofosu, FA; Sheppard, JA; Warkentin, TE | 1 |
| Ammollo, T; Colucci, M; Piro, D; Rossiello, MR; Semeraro, F | 1 |
| Belliard, A; Bonnet, ML; Hauet, T; Macchi, L; Mauco, G | 1 |
| Christersson, C; Johnell, M; Siegbahn, A | 1 |
| Fukuda, T; Furugohri, T; Kita, A; Morishima, Y; Shibano, T; Tsuji, N | 1 |
| Buetehorn, U; Heitmeier, S; Laux, V; Perzborn, E | 1 |
| Furugohri, T; Morishima, Y | 1 |
12 other study(ies) available for melagatran and thromboplastin
| Article | Year |
|---|---|
Effect of melagatran on prothrombin time assays depends on the sensitivity of the thromboplastin and the final dilution of the plasma sample.
Topics: Anticoagulants; Azetidines; Benzylamines; Blood Coagulation; Dose-Response Relationship, Drug; Glycine; Humans; Indicators and Reagents; Inhibitory Concentration 50; International Normalized Ratio; Prothrombin Time; Sensitivity and Specificity; Thromboplastin | 2001 |
Maximized hemostasis.
Topics: Animals; Azetidines; Benzylamines; Carboxypeptidase B2; Fibrinolysis; Glycine; Hemostasis; Humans; Mice; Mice, Knockout; Thrombin; Thrombolytic Therapy; Thromboplastin | 2002 |
Combined effects of melagatran and eptifibatide on platelet aggregation inhibition but not thrombin generation inhibition.
Topics: Azetidines; Benzylamines; Dose-Response Relationship, Drug; Drug Synergism; Eptifibatide; Factor Xa; Glycine; Humans; Peptide Fragments; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Prothrombin; Thrombin; Thromboplastin | 2004 |
Different antithrombotic properties of factor Xa inhibitor and thrombin inhibitor in rat thrombosis models.
Topics: Animals; Azetidines; Benzylamines; Blood Coagulation; Disease Models, Animal; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Fibrinolytic Agents; Glycine; Male; Naphthalenes; Propionates; Rats; Rats, Wistar; Thrombin; Thromboplastin; Thrombosis | 2005 |
Additive effects of anticoagulants: recombinant human activated protein C and heparin or melagatran, in tissue factor-activated umbilical-cord plasma.
Topics: Anticoagulants; Antithrombins; Azetidines; Benzylamines; Blood Coagulation; Blood Coagulation Tests; Dose-Response Relationship, Drug; Fetal Blood; Glycine; Heparin; Humans; Infant, Newborn; Protein C; Prothrombin Time; Recombinant Proteins; Thrombin; Thromboplastin; Umbilical Veins | 2005 |
Differences in the clinically effective molar concentrations of four direct thrombin inhibitors explain their variable prothrombin time prolongation.
Topics: Animals; Anticoagulants; Arginine; Azetidines; Benzylamines; Blood Coagulation; Cattle; Dose-Response Relationship, Drug; Factor Xa; Factor Xa Inhibitors; Glycine; Hirudins; Humans; In Vitro Techniques; Partial Thromboplastin Time; Peptide Fragments; Pipecolic Acids; Prothrombin Time; Recombinant Proteins; Species Specificity; Sulfonamides; Thrombin; Thrombin Time; Thromboplastin | 2005 |
Profibrinolytic activity of the direct thrombin inhibitor melagatran and unfractionated heparin in platelet-poor and platelet-rich clots.
Topics: Azetidines; Benzylamines; Blood Platelets; Carboxypeptidase B2; Dose-Response Relationship, Drug; Enzyme Activation; Fibrinolysis; Fibrinolytic Agents; Heparin; Humans; In Vitro Techniques; Partial Thromboplastin Time; Platelet-Rich Plasma; Thrombin; Thromboplastin; Time Factors; Tissue Plasminogen Activator | 2007 |
Melagatran prevents tissue factor expression in human platelet-monocyte heterotypic complexes.
Topics: Adult; Anticoagulants; Azetidines; Benzylamines; Blood Platelets; Humans; Middle Aged; Monocytes; P-Selectin; Protein Isoforms; Thromboplastin; Young Adult | 2008 |
The influence of direct thrombin inhibitors on the formation of platelet-leukocyte aggregates and tissue factor expression.
Topics: Antithrombins; Azetidines; Benzimidazoles; Benzylamines; beta-Alanine; Blood Platelets; Cell-Derived Microparticles; Dabigatran; Gene Expression; Humans; Leukocytes; Myocardial Infarction; Platelet Activation; Platelet Aggregation; RNA, Messenger; Thromboplastin | 2010 |
Melagatran, a direct thrombin inhibitor, but not edoxaban, a direct factor Xa inhibitor, nor heparin aggravates tissue factor-induced hypercoagulation in rats.
Topics: Animals; Antithrombins; Azetidines; Benzylamines; Blood Coagulation Disorders; Factor Xa Inhibitors; Heparin; Male; Pyridines; Rats; Rats, Wistar; Thiazoles; Thromboplastin | 2012 |
Direct thrombin inhibitors, but not the direct factor Xa inhibitor rivaroxaban, increase tissue factor-induced hypercoagulability in vitro and in vivo.
Topics: Animals; Antithrombins; Azetidines; Benzylamines; Blood Coagulation; Blood Platelets; Enzyme-Linked Immunosorbent Assay; Factor Xa Inhibitors; Humans; Male; Morpholines; Plasma; Platelet Count; Protein C; Prothrombin; Rats; Rats, Wistar; Rivaroxaban; Thiophenes; Thrombelastography; Thrombin; Thrombomodulin; Thrombophilia; Thromboplastin | 2014 |
Paradoxical enhancement of the intrinsic pathway-induced thrombin generation in human plasma by melagatran, a direct thrombin inhibitor, but not edoxaban, a direct factor Xa inhibitor, or heparin.
Topics: Anticoagulants; Antithrombins; Azetidines; Benzylamines; Blood Coagulation; Dose-Response Relationship, Drug; Drug Synergism; Factor Xa Inhibitors; Heparin; Humans; Pyridines; Thiazoles; Thrombin; Thromboplastin | 2015 |