Page last updated: 2024-09-05

melagatran and rivaroxaban

melagatran has been researched along with rivaroxaban in 3 studies

Compound Research Comparison

Studies (melagatran)	Trials (melagatran)	Recent Studies (post-2010) (melagatran)	Studies (rivaroxaban)	Trials (rivaroxaban)	Recent Studies (post-2010) (rivaroxaban)
185	32	19	4,741	569	4,357

Protein Interaction Comparison

Protein	Taxonomy	melagatran (IC50)	rivaroxaban (IC50)
Coagulation factor X	Homo sapiens (human)		0.0038

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fischer, PM	1
Fujimoto, T; Hiroe, K; Imaeda, Y; Kawamura, M; Konishi, N; Kubo, K; Shofuda, K	1
Buetehorn, U; Heitmeier, S; Laux, V; Perzborn, E	1

Reviews

1 review(s) available for melagatran and rivaroxaban

Article	Year
Design of Small-Molecule Active-Site Inhibitors of the S1A Family Proteases as Procoagulant and Anticoagulant Drugs. Journal of medicinal chemistry, 2018, 05-10, Volume: 61, Issue:9 Topics: Amino Acid Sequence; Animals; Anticoagulants; Blood Coagulation; Catalytic Domain; Humans; Peptide Hydrolases; Protease Inhibitors; Small Molecule Libraries	2018

Other Studies

2 other study(ies) available for melagatran and rivaroxaban

Article	Year
Antithrombotic and anticoagulant profiles of TAK-442, a novel factor Xa inhibitor, in a rabbit model of venous thrombosis. Journal of cardiovascular pharmacology, 2010, Volume: 56, Issue:2 Topics: Animals; Anticoagulants; Azetidines; Benzylamines; Bleeding Time; Blood Coagulation; Blood Coagulation Tests; Dogs; Factor Xa Inhibitors; Fibrinolytic Agents; Humans; Macaca fascicularis; Male; Mice; Mice, Inbred ICR; Morpholines; Pyrazoles; Pyridones; Pyrimidinones; Rabbits; Rats; Rats, Sprague-Dawley; Rivaroxaban; Sulfones; Thiophenes; Thrombin; Venous Thrombosis	2010
Direct thrombin inhibitors, but not the direct factor Xa inhibitor rivaroxaban, increase tissue factor-induced hypercoagulability in vitro and in vivo. Journal of thrombosis and haemostasis : JTH, 2014, Volume: 12, Issue:7 Topics: Animals; Antithrombins; Azetidines; Benzylamines; Blood Coagulation; Blood Platelets; Enzyme-Linked Immunosorbent Assay; Factor Xa Inhibitors; Humans; Male; Morpholines; Plasma; Platelet Count; Protein C; Prothrombin; Rats; Rats, Wistar; Rivaroxaban; Thiophenes; Thrombelastography; Thrombin; Thrombomodulin; Thrombophilia; Thromboplastin	2014

Article

Year

Antithrombotic and anticoagulant profiles of TAK-442, a novel factor Xa inhibitor, in a rabbit model of venous thrombosis.

Journal of cardiovascular pharmacology, 2010, Volume: 56, Issue:2

Topics: Animals; Anticoagulants; Azetidines; Benzylamines; Bleeding Time; Blood Coagulation; Blood Coagulation Tests; Dogs; Factor Xa Inhibitors; Fibrinolytic Agents; Humans; Macaca fascicularis; Male; Mice; Mice, Inbred ICR; Morpholines; Pyrazoles; Pyridones; Pyrimidinones; Rabbits; Rats; Rats, Sprague-Dawley; Rivaroxaban; Sulfones; Thiophenes; Thrombin; Venous Thrombosis

2010

Direct thrombin inhibitors, but not the direct factor Xa inhibitor rivaroxaban, increase tissue factor-induced hypercoagulability in vitro and in vivo.

Journal of thrombosis and haemostasis : JTH, 2014, Volume: 12, Issue:7

Topics: Animals; Antithrombins; Azetidines; Benzylamines; Blood Coagulation; Blood Platelets; Enzyme-Linked Immunosorbent Assay; Factor Xa Inhibitors; Humans; Male; Morpholines; Plasma; Platelet Count; Protein C; Prothrombin; Rats; Rats, Wistar; Rivaroxaban; Thiophenes; Thrombelastography; Thrombin; Thrombomodulin; Thrombophilia; Thromboplastin

2014