Compounds > melagatran
Page last updated: 2024-09-05

melagatran and propofol

melagatran has been researched along with propofol in 2 studies

Compound Research Comparison

Studies
(melagatran)		Trials
(melagatran)		Recent Studies (post-2010)
(melagatran)		Studies
(propofol)		Trials
(propofol)		Recent Studies (post-2010) (propofol)
185321916,8275,1886,805

Protein Interaction Comparison

ProteinTaxonomymelagatran (IC50)propofol (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)8.1667
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)9.393
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)7.596
Gamma-aminobutyric acid receptor subunit alpha-1Homo sapiens (human)8
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit gamma-2Homo sapiens (human)8
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)8.1667
Prostaglandin G/H synthase 1Homo sapiens (human)3.832
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)8.1667
Sodium-dependent noradrenaline transporter Homo sapiens (human)9.393
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)8.3
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit beta-3Homo sapiens (human)8
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)8.1667
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)8.3
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)8.3
5-hydroxytryptamine receptor 2BHomo sapiens (human)5.499
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)8.3
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)8.1667
GABA theta subunitRattus norvegicus (Norway rat)8.1667
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)8.1667

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1

Other Studies

2 other study(ies) available for melagatran and propofol

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008