melagatran has been researched along with fentanyl in 3 studies
| Studies (melagatran) | Trials (melagatran) | Recent Studies (post-2010) (melagatran) | Studies (fentanyl) | Trials (fentanyl) | Recent Studies (post-2010) (fentanyl) |
|---|---|---|---|---|---|
| 185 | 32 | 19 | 15,288 | 4,310 | 4,483 |
| Protein | Taxonomy | melagatran (IC50) | fentanyl (IC50) |
|---|---|---|---|
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 6.5 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.6342 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0122 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.1888 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0122 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0058 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.3092 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 5.893 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 1.58 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0031 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 1.8197 | |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | 4.973 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.354 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
3 other study(ies) available for melagatran and fentanyl
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |