melagatran has been researched along with ergotamine in 2 studies
| Studies (melagatran) | Trials (melagatran) | Recent Studies (post-2010) (melagatran) | Studies (ergotamine) | Trials (ergotamine) | Recent Studies (post-2010) (ergotamine) |
|---|---|---|---|---|---|
| 185 | 32 | 19 | 2,352 | 103 | 103 |
| Protein | Taxonomy | melagatran (IC50) | ergotamine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.056 | |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | 6.499 | |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | 3.16 | |
| Beta-2 adrenergic receptor | Homo sapiens (human) | 2.761 | |
| Beta-1 adrenergic receptor | Homo sapiens (human) | 4.142 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 1 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0021 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0043 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0038 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.012 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0008 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 1.728 | |
| Thromboxane-A synthase | Homo sapiens (human) | 3.064 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.049 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.0065 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.056 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.0008 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.0043 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0035 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.002 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
2 other study(ies) available for melagatran and ergotamine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |