Page last updated: 2024-09-05

melagatran and doxazosin

melagatran has been researched along with doxazosin in 2 studies

Compound Research Comparison

Studies
(melagatran)
Trials
(melagatran)
Recent Studies (post-2010)
(melagatran)
Studies
(doxazosin)
Trials
(doxazosin)
Recent Studies (post-2010) (doxazosin)
18532191,372439283

Protein Interaction Comparison

ProteinTaxonomymelagatran (IC50)doxazosin (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.544
Interstitial collagenaseHomo sapiens (human)5.749
Beta-2 adrenergic receptorHomo sapiens (human)2.748
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)2.2155
Alpha-1D adrenergic receptorHomo sapiens (human)0.0034
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.544
Sodium-dependent serotonin transporterHomo sapiens (human)2.688
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.368
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0007
Sodium-dependent dopamine transporter Homo sapiens (human)0.188
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.4022
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)2.2155

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1

Other Studies

2 other study(ies) available for melagatran and doxazosin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008