Page last updated: 2024-08-21

megestrol acetate and flutamide

megestrol acetate has been researched along with flutamide in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199010 (47.62)18.7374
1990's5 (23.81)18.2507
2000's2 (9.52)29.6817
2010's4 (19.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Curley, T; Dershaw, DD; Petrylak, D; Scher, HI; Seidman, AD1
Cusan, L; Labrie, C; Labrie, F; Lapointe, S; Plante, M1
Labrie, F; Lapointe, S; Plante, M1
Sogani, PC; Whitmore, WF1
Soloway, MS2
Fair, WR; Sogani, PC1
el Etreby, MF; Habenicht, UF; Louton, T; Nishino, Y; Schröder, HG1
Bruchovsky, N; Fletcher, T; Foekens, JA; Goldenberg, SL; Lawson, D; Rennie, PS1
Burton, S; Trachtenberg, J1
Geller, J1
Baird, A; Connors, KM; Geller, J; Hoffman, RM; Kohls, M; Sionit, LR1
Burger, CW; Greggi, S; Kenemans, P; van der Vange, N; Vermorken, JB1
McLeod, DG1
Burch, PA; Loprinzi, CL1

Reviews

3 review(s) available for megestrol acetate and flutamide

ArticleYear
Flutamide and other antiandrogens in the treatment of advanced prostatic carcinoma.
    Cancer treatment and research, 1988, Volume: 39

    Topics: Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents; Cyproterone; Cyproterone Acetate; Flutamide; Humans; Male; Megestrol; Megestrol Acetate; Prostatic Neoplasms

1988
Treatment of advanced prostatic cancer.
    The Urologic clinics of North America, 1987, Volume: 14, Issue:2

    Topics: Adrenalectomy; Aminoglutethimide; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyproterone; Cyproterone Acetate; Estrogens; Flutamide; Glucocorticoids; Humans; Ketoconazole; Male; Megestrol; Megestrol Acetate; Orchiectomy; Pituitary Hormone-Releasing Hormones; Prostatic Neoplasms; Spironolactone; Time Factors

1987
Antiandrogenic drugs.
    Cancer, 1993, Feb-01, Volume: 71, Issue:3 Suppl

    Topics: Androgen Receptor Antagonists; Anilides; Cyproterone Acetate; Diethylstilbestrol; Drug Administration Schedule; Flutamide; Humans; Imidazoles; Imidazolidines; Male; Megestrol; Megestrol Acetate; Nitriles; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Tosyl Compounds

1993

Trials

2 trial(s) available for megestrol acetate and flutamide

ArticleYear
Estramustine and vinblastine: use of prostate specific antigen as a clinical trial end point for hormone refractory prostatic cancer.
    The Journal of urology, 1992, Volume: 147, Issue:3 Pt 2

    Topics: Aged; Aged, 80 and over; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Diethylstilbestrol; Estramustine; Flutamide; Gonadotropin-Releasing Hormone; Humans; Male; Megestrol; Megestrol Acetate; Middle Aged; Orchiectomy; Prostate-Specific Antigen; Prostatic Neoplasms; Vinblastine

1992
Treatment of advanced prostatic cancer.
    The Urologic clinics of North America, 1987, Volume: 14, Issue:2

    Topics: Adrenalectomy; Aminoglutethimide; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyproterone; Cyproterone Acetate; Estrogens; Flutamide; Glucocorticoids; Humans; Ketoconazole; Male; Megestrol; Megestrol Acetate; Orchiectomy; Pituitary Hormone-Releasing Hormones; Prostatic Neoplasms; Spironolactone; Time Factors

1987

Other Studies

17 other study(ies) available for megestrol acetate and flutamide

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Analysis of the androgenic activity of synthetic "progestins" currently used for the treatment of prostate cancer.
    Journal of steroid biochemistry, 1987, Volume: 28, Issue:4

    Topics: Adrenal Glands; Animals; Chlormadinone Acetate; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Flutamide; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Megestrol; Megestrol Acetate; Organ Size; Ornithine Decarboxylase; Progesterone Congeners; Prostate; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Spironolactone

1987
Stimulatory effect of synthetic progestins currently used for the treatment of prostate cancer on growth of the androgen-sensitive Shionogi tumor in mice.
    Journal of steroid biochemistry, 1988, Volume: 31, Issue:1

    Topics: Androgens; Animals; Chlormadinone Acetate; Cyproterone; Cyproterone Acetate; Female; Flutamide; Male; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Megestrol; Megestrol Acetate; Mice; Progesterone Congeners; Prostatic Neoplasms

1988
Treatment of prostatic cancer. Newer forms of androgen deprivation.
    Postgraduate medicine, 1986, Volume: 80, Issue:1

    Topics: Androgen Antagonists; Cyproterone; Cyproterone Acetate; Flutamide; Humans; Male; Megestrol; Megestrol Acetate; Neoplasm Metastasis; Orchiectomy; Pituitary Hormone-Releasing Hormones; Prostatic Neoplasms

1986
Effect of cyproterone acetate in comparison to flutamide and megestrol acetate on the ventral prostate, seminal vesicle, and adrenal glands of adult male rats.
    The Prostate, 1987, Volume: 11, Issue:4

    Topics: Adrenal Glands; Androgen Antagonists; Animals; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Male; Megestrol; Megestrol Acetate; Orchiectomy; Organ Size; Prostate; Rats; Rats, Inbred Strains; Seminal Vesicles

1987
Relative effectiveness of alternative androgen withdrawal therapies in initiating regression of rat prostate.
    The Journal of urology, 1988, Volume: 139, Issue:6

    Topics: Anilides; Animals; Cyproterone; Cyproterone Acetate; Diethylstilbestrol; Dihydrotestosterone; Flutamide; Gonadotropin-Releasing Hormone; Imidazoles; Imidazolidines; Leuprolide; Male; Megestrol; Megestrol Acetate; Orchiectomy; Prostate; Rats; Rats, Inbred Strains; Receptors, Androgen

1988
Effectiveness of antiandrogens in the rat.
    The Journal of urology, 1986, Volume: 136, Issue:4

    Topics: Androgen Antagonists; Animals; Flutamide; Imidazoles; Imidazolidines; Male; Megestrol; Megestrol Acetate; Orchiectomy; Prostate; Rats; Rats, Inbred Strains; Seminal Vesicles; Testosterone

1986
Rationale for blockade of adrenal as well as testicular androgens in the treatment of advanced prostate cancer.
    Seminars in oncology, 1985, Volume: 12, Issue:1 Suppl 1

    Topics: Adrenal Glands; Androgen Antagonists; Dihydrotestosterone; Estrogens; Flutamide; Gonadotropin-Releasing Hormone; Humans; Male; Megestrol; Megestrol Acetate; Prostatic Neoplasms; Testis

1985
Newer methods of hormonal therapy for prostate cancer.
    Urology, 1984, Volume: 24, Issue:5 Suppl

    Topics: Adenocarcinoma; Aminoglutethimide; Androgen Antagonists; Bone Neoplasms; Buserelin; Flutamide; Gonadotropin-Releasing Hormone; Humans; Leuprolide; Male; Megestrol; Megestrol Acetate; Pituitary Hormone-Releasing Hormones; Prostatic Neoplasms

1984
In vivo and in vitro effects of androgen on fibroblast growth factor-2 concentrations in the human prostate.
    The Prostate, 1994, Volume: 25, Issue:4

    Topics: Androgen Antagonists; Cell Division; Culture Techniques; Dihydrotestosterone; Fibroblast Growth Factor 2; Flutamide; Humans; Male; Megestrol; Megestrol Acetate; Orchiectomy; Prostate; Prostatic Hyperplasia; Radioimmunoassay

1994
Experience with hormonal therapy in advanced epithelial ovarian cancer.
    Acta oncologica (Stockholm, Sweden), 1995, Volume: 34, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Carcinoma; Estrogen Antagonists; Female; Flutamide; Gonadotropin-Releasing Hormone; Humans; Luteolytic Agents; Medroxyprogesterone Acetate; Megestrol; Megestrol Acetate; Middle Aged; Ovarian Neoplasms; Progesterone Congeners; Remission Induction; Survival Rate; Tamoxifen; Triptorelin Pamoate

1995
Prostate-specific antigen decline after withdrawal of low-dose megestrol acetate.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:3

    Topics: Antineoplastic Agents, Hormonal; Combined Modality Therapy; Flutamide; Humans; Male; Megestrol Acetate; Middle Aged; Orchiectomy; Prostate-Specific Antigen; Prostatic Neoplasms

1999