Page last updated: 2024-09-02

mefloquine-sulfadoxine-pyrimethamine and sulfadoxine

mefloquine-sulfadoxine-pyrimethamine has been researched along with sulfadoxine in 39 studies

Compound Research Comparison

Studies
(mefloquine-sulfadoxine-pyrimethamine)
Trials
(mefloquine-sulfadoxine-pyrimethamine)
Recent Studies (post-2010)
(mefloquine-sulfadoxine-pyrimethamine)
Studies
(sulfadoxine)
Trials
(sulfadoxine)
Recent Studies (post-2010) (sulfadoxine)
432002,417586742

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199018 (46.15)18.7374
1990's19 (48.72)18.2507
2000's2 (5.13)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bunnag, D; Chindanond, D; Chittamas, S; Fernex, M; Harinasuta, T; Kristiansen, S; Malikul, S; Mittelholzer, ML; Sturchler, D1
Adio, RA; Dickschat, U; Mittelholzer, ML; Reber-Liske, R; Salako, LA; Sowunmi, A; Stürchler, D; Walker, O1
Bunnag, D; Chitamas, S; Harinasuta, T; Karbwang, J; Viravan, C1
Chongsuphajaisiddhi, T; Frejacques, L; Luxemburger, C; Nosten, F; ter Kuiile, F; White, NJ1
Holdener, F; Nurminen, L; Steffen, R; Wyss, R1
Chongsuphajaisiddhi, T; Edstein, MD; Lika, ID; Sabchareon, A; Webster, HK1
Malikul, S; Pinichpongse, S; Rooney, W; Tansophalaks, S; Thimasarn, K1
Eberlé, F; Gazin, P; Gelas, H; Hengy, C; Jambou, R; Kouka-Bemba, D1
Karbwang, J; White, NJ1
Cappelletti, G; Guenzi, A; Scala, A; Zanetti, M1
Prociv, P1
Aina Adio, R; Fadeke Aderounmu, A; Laoye, AJ; Modupe Makinde, J; Salako, LA1
Kollaritsch, H; Kollaritsch, R; Kremsner, P; Leimer, R; Mailer, H; Stemberger, H; Wiedermann, G1
Hlaing, N; Lasserre, R; Tin, F; Tun, T; Win, S1
Kharazmi, A; Nielsen, H1
Fernex, M1
Beeching, NJ; Eales, M; Ellis-Pegler, RB; Fraser, AG; Wells, AU1
Aderounmu, AF; Adio, RA; Laoye, JO; Makinde, JM; Salako, LA1
Arnold, K; Chen, PQ; Fu, LC; Guo, XB; Li, GQ1
Asthana, OP; Nityanand, S; Tangri, AN1
de Souza, JM; Doberstyn, EB; Sheth, UK; Trigg, PI; Wernsdorfer, WH1
Bunnag, D; Charoenlarp, P; Chitamas, S; Harinasuta, T; Sheth, UK; Suntharasmai, P; Vanijanond, S; Wernsdorfer, WH1
Ekue, JM; Mukunyandela, M; Phiri, DE; Sheth, UK1
Heizmann, P; Mimica, I; Portmann, R; Schwartz, DE; Weidekamm, E1
Dubach, UC; Schwartz, DE; Weber, B; Weidekamm, E1
Danis, M; Félix, H; Rosenheim, M1
Cavalcante, EQ; de Oliveira, RM; de Souza, JM; Gomes, AT; Sheth, UK1
Duong, TH; Igwangou, P; Kombila, M; Ngou-Milama, E; Ozouaki, P1
Chatnugrob, P; Eamsila, C; Lasserre, R; Mittelholzer, ML; Nopavong Na Ayuthya, A; Singharaj, P; Stürchler, D; Webster, HK; Yooyen, P1
Bangchang, KN; Bunnag, D; Harinasuta, T; Karbwang, J; Rooney, W; Thimasarn, K1
Banmairuroi, V; Bunnag, D; Harinasuta, T; Karbwang, J; Na Bangchang, K1
Mittelholzer, ML; Stürchler, D1
Schubarth, P1
Laomiphol, A; Palananth, C; Rooney, W; Sirichaisinthop, J; Tansophalaks, S; Tháithong, S; Thamewat, U; Thimasarn, K; Vijaykadga, S; Yamokgul, P1
Coppel, RL; Marshall, VM; Tieqiao, W1
Alaribe, AA; Chukwuani, CM; Ekanem, OJ; Ezedinachi, EN; Haller, L; Meremikwu, MM; Ojar, EA; Umotong, AB1
Granier, H; Laborde, JP; Martin, J; Nicolas, X; Talarmin, F1
Shen, WJ; Thiero, M1

Reviews

3 review(s) available for mefloquine-sulfadoxine-pyrimethamine and sulfadoxine

ArticleYear
Clinical pharmacokinetics of mefloquine.
    Clinical pharmacokinetics, 1990, Volume: 19, Issue:4

    Topics: Animals; Antimalarials; Drug Combinations; Drug Interactions; Humans; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Sulfadoxine

1990
[Malaria in Switzerland].
    Schweizerische medizinische Wochenschrift, 1988, Dec-10, Volume: 118, Issue:49

    Topics: Animals; Antimalarials; Drug Combinations; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Sulfadoxine; Switzerland

1988
[Malaria: the most important emergency in subjects returning from the tropics].
    Schweizerische medizinische Wochenschrift, 1993, May-01, Volume: 123, Issue:17

    Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Emergencies; Humans; Malaria; Malaria, Falciparum; Mefloquine; Plasmodium; Pyrimethamine; Quinidine; Quinine; Sulfadoxine

1993

Trials

17 trial(s) available for mefloquine-sulfadoxine-pyrimethamine and sulfadoxine

ArticleYear
Fansimef for prophylaxis of malaria: a double-blind randomized placebo controlled trial.
    The Southeast Asian journal of tropical medicine and public health, 1992, Volume: 23, Issue:4

    Topics: Adolescent; Adult; Antimalarials; Chloroquine; Double-Blind Method; Drug Combinations; Humans; Incidence; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Pyrimethamine; Sulfadoxine; Treatment Outcome

1992
Mefloquine-sulphadoxine-pyrimethamine (Fansimef, Roche) in the prophylaxis of Plasmodium falciparum malaria: a double-blind, comparative, placebo-controlled study.
    Annals of tropical medicine and parasitology, 1992, Volume: 86, Issue:6

    Topics: Adolescent; Adult; Antimalarials; Chloroquine; Double-Blind Method; Drug Combinations; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Pyrimethamine; Sulfadoxine

1992
Clinical trials of mefloquine with tetracycline.
    The Southeast Asian journal of tropical medicine and public health, 1992, Volume: 23, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Prospective Studies; Pyrimethamine; Sulfadoxine; Tetracycline

1992
Phase III double-blind comparative study of Fansimef and Lariam for the curative treatment of Plasmodium falciparum infections in Thailand.
    The Southeast Asian journal of tropical medicine and public health, 1990, Volume: 21, Issue:3

    Topics: Adult; Animals; Antimalarials; Double-Blind Method; Drug Combinations; Drug Resistance; Female; Follow-Up Studies; Humans; Malaria; Male; Mefloquine; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Thailand

1990
Comparison of the susceptibility of falciparum malaria to mefloquine-sulphadoxine-pyrimethamine and chloroquine in Nigeria.
    African journal of medicine and medical sciences, 1988, Volume: 17, Issue:4

    Topics: Animals; Antimalarials; Child; Chloroquine; Clinical Trials as Topic; Drug Administration Schedule; Drug Combinations; Drug Resistance; Female; Humans; Malaria; Male; Mefloquine; Nigeria; Plasmodium falciparum; Pyrimethamine; Quinolines; Random Allocation; Sulfadoxine; Sulfanilamides

1988
Tolerability of long-term malaria prophylaxis with the combination mefloquine + sulfadoxine + pyrimethamine (Fansimef): results of a double blind field trial versus chloroquine in Nigeria.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, Volume: 82, Issue:4

    Topics: Adolescent; Adult; Animals; Antimalarials; Aspartate Aminotransferases; Blood Cell Count; Child; Chloroquine; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; gamma-Glutamyltransferase; Humans; Malaria; Male; Mefloquine; Middle Aged; Nigeria; Plasmodium falciparum; Pyrimethamine; Quinolines; Random Allocation; Sulfadoxine; Sulfanilamides

1988
Sensitivity of Plasmodium falciparum to mefloquine-sulphadoxine-pyrimethamine (Fansimef) in vivo and to mefloquine alone in vitro in Nigeria.
    Annals of tropical medicine and parasitology, 1988, Volume: 82, Issue:4

    Topics: Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Evaluation; Drug Resistance; Female; Humans; Malaria; Male; Mefloquine; Nigeria; Plasmodium falciparum; Pyrimethamine; Quinolines; Random Allocation; Sulfadoxine; Sulfanilamides

1988
Double-blind dose finding study of mefloquine-sulfadoxine-pyrimethamine in children with acute falciparum malaria.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, Volume: 82, Issue:4

    Topics: Adolescent; Animals; Antimalarials; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Malaria; Male; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Sulfadoxine; Sulfanilamides

1988
Clinical trial of fansimef in Indian patients of P. falciparum malaria.
    Indian journal of malariology, 1988, Volume: 25, Issue:2

    Topics: Adolescent; Adult; Animals; Antimalarials; Clinical Trials as Topic; Drug Combinations; Humans; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Prospective Studies; Pyrimethamine; Sulfadoxine; Sulfanilamides

1988
A phase II/III double-blind, dose-finding clinical trial of a combination of mefloquine, sulfadoxine, and pyrimethamine (Fansimef) in falciparum malaria.
    Bulletin of the World Health Organization, 1987, Volume: 65, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Animals; Antimalarials; Brazil; Double-Blind Method; Drug Combinations; Drug Evaluation; Humans; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Pyrimethamine; Quinolines; Random Allocation; Sulfadoxine; Sulfanilamides

1987
Mefloquine, sulfadoxine, and pyrimethamine in the treatment of symptomatic falciparum malaria: a double-blind trial for determining the most effective dose.
    Bulletin of the World Health Organization, 1987, Volume: 65, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Animals; Antimalarials; Double-Blind Method; Drug Combinations; Humans; Malaria; Male; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Random Allocation; Sulfadoxine; Sulfanilamides; Thailand

1987
A double-blind trial of a fixed combination of mefloquine plus sulfadoxine-pyrimethamine compared with sulfadoxine-pyrimethamine alone in symptomatic falciparum malaria.
    Bulletin of the World Health Organization, 1987, Volume: 65, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Animals; Antimalarials; Child; Double-Blind Method; Drug Combinations; Humans; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Pyrimethamine; Quinolines; Random Allocation; Sulfadoxine; Sulfanilamides

1987
A phase I clinical trial of Fansimef (mefloquine plus sulfadoxine-pyrimethamine) in Brazilian male subjects.
    Bulletin of the World Health Organization, 1985, Volume: 63, Issue:3

    Topics: Adult; Brazil; Double-Blind Method; Drug Combinations; Drug Evaluation; Humans; Malaria; Male; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Random Allocation; Sulfadoxine; Sulfanilamides

1985
Prevention of Plasmodium falciparum malaria by Fansimef and Lariam in the northeastern part of Thailand.
    The Southeast Asian journal of tropical medicine and public health, 1993, Volume: 24, Issue:4

    Topics: Adult; Animals; Antibodies, Protozoan; Blood; Chloroquine; Drug Combinations; Humans; Malaria, Falciparum; Male; Mefloquine; Military Personnel; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Thailand

1993
Mefloquine monitoring in acute uncomplicated malaria treated with Fansimef and Lariam.
    The Southeast Asian journal of tropical medicine and public health, 1993, Volume: 24, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Antimalarials; Drug Combinations; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Pyrimethamine; Sulfadoxine

1993
In vivo study of the response of Plasmodium falciparum to standard mefloquine/sulfadoxine/pyrimethamine (MSP) treatment among gem miners returning from Cambodia.
    The Southeast Asian journal of tropical medicine and public health, 1995, Volume: 26, Issue:2

    Topics: Adult; Animals; Antimalarials; Cambodia; Chi-Square Distribution; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Mining; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Thailand; Transients and Migrants

1995
[Coartem and fansimef in the treatment of falciparum malaria].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2006, Feb-28, Volume: 24, Issue:1

    Topics: Abdominal Pain; Adolescent; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fever; Fluorenes; Humans; Malaria, Falciparum; Male; Mali; Mefloquine; Nausea; Pyrimethamine; Skin; Sulfadoxine; Time Factors; Treatment Outcome

2006

Other Studies

19 other study(ies) available for mefloquine-sulfadoxine-pyrimethamine and sulfadoxine

ArticleYear
Mefloquine plus sulfadoxine and pyrimethamine.
    Lancet (London, England), 1991, Jul-06, Volume: 338, Issue:8758

    Topics: Animals; Drug Combinations; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Sulfadoxine

1991
Mefloquine for multidrug-resistant malaria.
    Lancet (London, England), 1991, Nov-16, Volume: 338, Issue:8777

    Topics: Animals; Antimalarials; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Psychoses, Substance-Induced; Pyrimethamine; Refugees; Sulfadoxine

1991
Malaria prophylaxis and self-therapy in airline crews.
    Aviation, space, and environmental medicine, 1990, Volume: 61, Issue:10

    Topics: Aerospace Medicine; Africa; Animals; Antimalarials; Culicidae; Drug Combinations; Drug Resistance; Emergencies; Humans; Incidence; Insect Bites and Stings; Malaria; Mefloquine; Patient Compliance; Protective Clothing; Pyrimethamine; Self Medication; Sulfadoxine

1990
Quantitation of Fansimef components (mefloquine + sulfadoxine + pyrimethamine) in human plasma by two high-performance liquid chromatographic methods.
    Therapeutic drug monitoring, 1991, Volume: 13, Issue:2

    Topics: Antimalarials; Child; Chromatography, High Pressure Liquid; Drug Combinations; Humans; Male; Mefloquine; Pyrimethamine; Sulfadoxine

1991
[Uncomplicated malaria attack in an area with high resistance to chloroquine. 3. The use of second-choice oral drug treatment].
    Bulletin de la Societe de pathologie exotique (1990), 1990, Volume: 83, Issue:1

    Topics: Adolescent; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Infant; Malaria; Male; Mefloquine; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides

1990
Simultaneous determination of pyrimethamine and mefloquine in human plasma by high-performance liquid chromatography with ultraviolet detection.
    Journal of chromatography, 1989, Sep-29, Volume: 494

    Topics: Antimalarials; Chromatography, High Pressure Liquid; Drug Combinations; Humans; Mefloquine; Pyrimethamine; Spectrophotometry, Ultraviolet; Sulfadoxine

1989
Fansimef in the treatment of malaria.
    Australian and New Zealand journal of medicine, 1989, Volume: 19, Issue:4

    Topics: Animals; Antimalarials; Drug Combinations; Humans; Malaria; Mefloquine; Plasmodium vivax; Pyrimethamine; Quinolines; Sulfadoxine; Sulfanilamides

1989
Falciparum malaria treated with a fixed combination of mefloquine, sulfadoxine and pyrimethamine: a field study in adults in Burma.
    Bulletin of the World Health Organization, 1985, Volume: 63, Issue:4

    Topics: Adolescent; Adult; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Malaria; Male; Mefloquine; Middle Aged; Myanmar; Plasmodium falciparum; Pyrimethamine; Quinolines; Sulfadoxine; Sulfanilamides

1985
In vitro effect of fansimef on human neutrophil and monocyte function.
    European journal of clinical pharmacology, 1986, Volume: 29, Issue:5

    Topics: Blood Bactericidal Activity; Chemotaxis; Drug Combinations; Humans; In Vitro Techniques; Luminescent Measurements; Mefloquine; Monocytes; Neutrophils; Nitroblue Tetrazolium; Oxidation-Reduction; Phagocytosis; Pyrimethamine; Quinolines; Sulfadoxine; Sulfanilamides; Superoxides

1986
Fansimef [Fansidar plus mefloquine] is effective treatment for imported malaria in New Zealand.
    Australian and New Zealand journal of medicine, 1988, Volume: 18, Issue:5

    Topics: Adolescent; Adult; Animals; Child; Drug Combinations; Female; Humans; Malaria; Male; Mefloquine; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinolines; Sulfadoxine; Sulfanilamides

1988
Multiple-dose pharmacokinetics of the antimalarial drug Fansimef (pyrimethamine + sulfadoxine + mefloquine) in healthy subjects.
    Chemotherapy, 1987, Volume: 33, Issue:1

    Topics: Adult; Antimalarials; Drug Combinations; Female; Half-Life; Humans; Kinetics; Male; Mefloquine; Metabolic Clearance Rate; Middle Aged; Pyrimethamine; Quinolines; Sulfadoxine; Sulfanilamides

1987
Single-dose investigation of possible interactions between the components of the antimalarial combination Fansimef.
    Chemotherapy, 1987, Volume: 33, Issue:4

    Topics: Adult; Antimalarials; Biological Availability; Blood Proteins; Drug Combinations; Drug Interactions; Erythrocytes; Half-Life; Humans; Kinetics; Male; Mefloquine; Middle Aged; Protein Binding; Pyrimethamine; Quinolines; Sulfadoxine; Sulfanilamides

1987
[Making good use of mefloquine].
    Bulletin de la Societe de pathologie exotique et de ses filiales, 1985, Volume: 78, Issue:5 Pt 2

    Topics: Adult; Antimalarials; Child; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Mefloquine; Pyrimethamine; Quinolines; Sulfadoxine

1985
[Variation of cholostase enzymes (5'-nucleotidase and alkaline phosphatase) during a specific treatment for malaria in the Gabonese child].
    Bulletin de la Societe de pathologie exotique (1990), 1995, Volume: 88, Issue:1

    Topics: 5'-Nucleotidase; Alkaline Phosphatase; Antimalarials; Child; Child, Preschool; Drug Combinations; Gabon; Humans; Infant; Malaria; Mefloquine; Phenanthrenes; Pyrimethamine; Reference Values; Sulfadoxine

1995
Mefloquine level monitoring in patients with multidrug resistant Plasmodium falciparum on the Thai Myanmar border.
    The Southeast Asian journal of tropical medicine and public health, 1993, Volume: 24, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Cambodia; Chromatography, High Pressure Liquid; Drug Combinations; Drug Monitoring; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Primaquine; Pyrimethamine; Sulfadoxine; Thailand; Treatment Outcome

1993
[Emergency treatment of malaria during travel].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1993, Aug-31, Volume: 82, Issue:35

    Topics: Antimalarials; Drug Combinations; Emergencies; Humans; Malaria; Mefloquine; Patient Education as Topic; Pyrimethamine; Sulfadoxine; Travel

1993
Close linkage of three merozoite surface protein genes on chromosome 2 of Plasmodium falciparum.
    Molecular and biochemical parasitology, 1998, Jul-01, Volume: 94, Issue:1

    Topics: Amino Acid Sequence; Animals; Antibodies, Protozoan; Antigens, Protozoan; Antimalarials; Base Sequence; Chromosomes; DNA, Complementary; DNA, Protozoan; Drug Combinations; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique, Indirect; Genes, Protozoan; Immunoblotting; Mefloquine; Membrane Proteins; Molecular Sequence Data; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins; Pyrimethamine; Rabbits; Sulfadoxine

1998
Efficacy and tolerability of a low-dose mefloquine-sulfadoxine-pyrimethamine combination compared with chloroquine in the treatment of acute malaria infection in a population with multiple drug-resistant Plasmodium falciparum.
    The American journal of tropical medicine and hygiene, 1999, Volume: 61, Issue:1

    Topics: Adolescent; Adult; Animals; Antimalarials; Blood; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Nigeria; Plasmodium falciparum; Prospective Studies; Pyrimethamine; Random Allocation; Sulfadoxine

1999
[Danger of malaria self-treatment. Acute neurologic toxicity of mefloquine and its combination with pyrimethamine-sulfadoxine].
    Presse medicale (Paris, France : 1983), 2001, Sep-29, Volume: 30, Issue:27

    Topics: Adult; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Humans; Malaria; Male; Mefloquine; Pyrimethamine; Self Medication; Sulfadoxine

2001