mefloquine hydrochloride and tafenoquine

mefloquine hydrochloride has been researched along with tafenoquine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ager, A; Ellis, W; Guan, J; Kyle, D; Lin, AJ; Milhous, W; Sacci, J; Zhang, Q1
Fitos, I; Mády, G; Visy, J; Zsila, F1
Brennan, L; Edstein, MD; Harris, IE; Kerr, C; Kitchener, SJ; Leggat, PA; Nasveld, PE; Ohrt, C; Pickford, P; Prescott, W; Reid, M1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Carvalho, L; Castanys, S; Gamarro, F; Manzano, JI; Pérez-Victoria, JM1

Trials

1 trial(s) available for mefloquine hydrochloride and tafenoquine

ArticleYear
Randomized, double-blind study of the safety, tolerability, and efficacy of tafenoquine versus mefloquine for malaria prophylaxis in nonimmune subjects.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:2

    Topics: Adult; Aminoquinolines; Antimalarials; Australia; Double-Blind Method; Female; Humans; Malaria; Male; Mefloquine; Middle Aged; Military Personnel; Treatment Outcome; Young Adult

2010

Other Studies

4 other study(ies) available for mefloquine hydrochloride and tafenoquine

ArticleYear
Unambiguous synthesis and prophylactic antimalarial activities of imidazolidinedione derivatives.
    Journal of medicinal chemistry, 2005, Oct-06, Volume: 48, Issue:20

    Topics: Administration, Oral; Animals; Antimalarials; Carbamates; Guanidines; Imidazoles; Imidazolidines; Malaria; Male; Mice; Plasmodium falciparum; Plasmodium yoelii; Structure-Activity Relationship

2005
Selective plasma protein binding of antimalarial drugs to alpha1-acid glycoprotein.
    Bioorganic & medicinal chemistry, 2008, Apr-01, Volume: 16, Issue:7

    Topics: Antimalarials; Binding Sites; Chromatography, Affinity; Circular Dichroism; Humans; Molecular Structure; Orosomucoid; Protein Binding; Serum Albumin; Spectrophotometry; Stereoisomerism; Structure-Activity Relationship

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Increased glycolytic ATP synthesis is associated with tafenoquine resistance in Leishmania major.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:3

    Topics: Adenosine Triphosphate; Aminoquinolines; Antiprotozoal Agents; Drug Resistance; Glycolysis; Leishmania major; Pyruvate Kinase

2011