mefloquine hydrochloride and quinine

mefloquine hydrochloride has been researched along with quinine in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	12 (32.43)	18.2507
2000's	20 (54.05)	29.6817
2010's	4 (10.81)	24.3611
2020's	1 (2.70)	2.80

Authors

Authors	Studies
Agnamey, P; Azas, N; Cohen, A; Damiani, C; Dassonville-Klimpt, A; Dormoi, J; Guillon, J; Marchivie, M; Mullié, C; Pradines, B; Schneider, J; Sonnet, P; Taudon, N; Tisnerat, C; Totet, A	1
Angerhofer, CK; König, GM; Pezzuto, JM; Sticher, O; Wright, AD	1
Angerhofer, CK; Chai, H; Cordell, GA; Hu, SF; Lin, J; Lin, LZ; Pezzuto, JM; Zaw, K; Zheng, DM	1
Denny, WA; Figgitt, DP; Gamage, SA; Ralph, RK; Tepsiri, N; Wilairat, P; Wojcik, SJ	1
Angerhofer, CK; Chai, H; Cordell, GA; Likhitwitayawuid, K; Pezzuto, JM; Ruangrungsi, N	2
Cabral, JA; McChesney, JD; Milhous, WK	1
Angerhofer, CK; Cordell, GA; Likhitwitayawuid, K; Pezzuto, JM; Ruangrungsi, N	1
Angerhofer, CK; Desqueyroux-Faúndez, R; Greenidge, P; König, GM; Linden, A; Wright, AD	1
Angerhofer, CK; Böhlke, M; Farnsworth, NR; Guinaudeau, H; Mora, GA; Poveda, LJ; Soejarto, DD; Wongpanich, V	1
Angerhofer, C; Arnason, JT; Durst, T; Gbeassor, M; MacKinnon, S; Pezzuto, J; Poveda, LJ; Sanchez-Vindas, PE	1
Cimanga, K; De Bruyne, T; Pieters, L; Turger, CA; Vlietinck, AJ	1
Angerhofer, CK; Cordell, GA; Guinaudeau, H; Pezzuto, JM; Wongpanich, V	1
Angenot, L; Brandt, V; De Pauw, M; DeMol, P; Frédérich, M; Hayette, M; Penelle, J; Prosperi, C; Tits, M	1
Jomaa, H; Mitsch, A; Schlitzer, M; Wiesner, J; Wissner, P	1
Angerhofer, CK; Cordell, GA; Han, J; Kim, SU; Lee, JG; Min, SS; Park, SH	1
Ager, A; Alvim-Gaston, M; Avery, MA; Charman, W; Peters, W; Robinson, BL; Vroman, JA; Wu, B	1
Bohle, DS; Fotie, J; Georges, E; Leimanis, ML; Nkengfack, AE; Rukunga, G	1
Chen, X; Chong, CR; Liu, JO; Shi, L; Sullivan, DJ	1
Angerhofer, CK; de Nys, R; Gurrath, M; Pezzuto, JM; Wright, AD	1
Fukuda, M; Jongsakul, K; Knirsch, C; Krudsood, S; Leowattana, W; Looareesuwan, S; Miller, RS; Noedl, H; Ohrt, C; Sriwichai, S; Tangpukdee, N; Thanachartwet, W; Yingyuen, K	1
Baniecki, ML; Clardy, J; Wirth, DF	1
Dennull, RA; Gerena, L; Johnson, JD; Lopez-Sanchez, M; Roncal, NE; Waters, NC	1
Dodean, RA; Gard, GL; Kelly, JX; Peyton, D; Riscoe, MK; Winter, RW	1
Egan, TJ; Hoppe, HC; Joiner, KA; Roberts, L	1
de L Ferreira, M; de Souza, MV; Kaiser, CR; Lourenço, MC; Pais, KC; Peralta, MA	1
Bambal, RB; Bates, M; Berry, N; Biagini, GA; Bonar-Law, R; Bray, PG; Brigandi, RA; Davis, CB; Gargallo, DV; Gibbons, P; Gomez-delas-Heras, FM; Gresham, SL; Hart, TK; Hindley, S; Lawrence, RM; Maggs, JL; Mukhtar, A; O'Neill, PM; Park, BK; Roberts, P; Shone, AE; Stocks, PA; Ward, SA; Winstanley, PA	1
Bacon, DJ; Escalante, AA; Griffing, SM; Haley, R; Lucas, C; McCollum, AM; Salas, C; Santolalla, M; Soberon, V; Tsukayama, P; Udhayakumar, V	1
Asadollahy, E; Bambal, RB; Bates, M; Berry, N; Biagini, G; Bray, PG; Brigandi, RA; Davies, J; Davis, CB; Gargallo, DV; Gomez-de-Las-Heras, FM; Gresham, SL; Hall, C; Hindley, S; Lander, H; Maggs, JL; Nixon, G; O'Neill, PM; Parapini, S; Park, BK; Rimmer, K; Roberts, P; Shone, AE; Stanford, D; Stocks, PA; Taramelli, D; Vivas, L; Ward, SA; Winstanley, PA	1
Almeras, L; Amalvict, R; Baret, E; Briolant, S; Fusaï, T; Henry, M; Parquet, V; Pradines, B; Rogier, C; Torrentino-Madamet, M	1
Masseno, V; Muriithi, S; Nzila, A	1
Fuehrer, HP; Haque, R; Hofecker, V; Khan, WA; Ley, B; Noedl, H; Siedl, A; Starzengruber, P; Thriemer, K; Wernsdorfer, WH	1
Andrianaranjaka, V; Andriantsoanirina, V; Bouchier, C; Durand, R; Jahevitra, M; Ménard, D; Mercereau-Puijalon, O; Rabarijaona, LP; Rabearimanana, S; Radrianjafy, R; Randriantsoa, T; Rason, MA; Ratsimbasoa, A; Tichit, M	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Carvalho, L; Castanys, S; Gamarro, F; Manzano, JI; Pérez-Victoria, JM	1
de Dios, A; Gorka, AP; Roepe, PD	1
Aroonkit, P; Krajangsri, S; Mungthin, M; Ruchirawat, S; Thongsornkleeb, C; Tummatorn, J	1

Reviews

2 review(s) available for mefloquine hydrochloride and quinine

Article	Year
Antimalarial activity: the search for marine-derived natural products with selective antimalarial activity. Journal of natural products, 1996, Volume: 59, Issue:7 Topics: Animals; Antimalarials; Magnetic Resonance Spectroscopy; Marine Toxins; Plants; Plasmodium; Porifera; Rhodophyta; Structure-Activity Relationship	1996
Quinoline drug-heme interactions and implications for antimalarial cytostatic versus cytocidal activities. Journal of medicinal chemistry, 2013, Jul-11, Volume: 56, Issue:13 Topics: Antimalarials; Crystallization; Drug Resistance; Heme; Hemeproteins; Humans; Malaria, Falciparum; Molecular Structure; Plasmodium falciparum; Quinolines	2013

Other Studies

35 other study(ies) available for mefloquine hydrochloride and quinine

Article	Year
Design, synthesis, and characterization of novel aminoalcohol quinolines with strong in vitro antimalarial activity. European journal of medicinal chemistry, 2022, Jan-15, Volume: 228 Topics: Amino Alcohols; Animals; Antimalarials; Cell Line; Cricetulus; Dose-Response Relationship, Drug; Drug Design; Ether-A-Go-Go Potassium Channels; Female; Humans; Malaria; Mice; Mice, Inbred BALB C; Microsomes, Liver; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Structure-Activity Relationship	2022
Antimalarial activity of sesquiterpenes from the marine sponge Acanthella klethra. Journal of natural products, 1992, Volume: 55, Issue:12 Topics: Animals; Antimalarials; Cell Survival; Humans; KB Cells; Plasmodium falciparum; Porifera; Sesquiterpenes	1992
Thalifaberidine, a cytotoxic aporphine-benzylisoquinoline alkaloid from Thalictrum faberi. Journal of natural products, 1994, Volume: 57, Issue:10 Topics: Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Aporphines; Drugs, Chinese Herbal; HIV; Humans; Magnetic Resonance Spectroscopy; Medicine, Chinese Traditional; Mice; Reverse Transcriptase Inhibitors; Tumor Cells, Cultured	1994
Synthesis and in vitro evaluation of 9-anilino-3,6-diaminoacridines active against a multidrug-resistant strain of the malaria parasite Plasmodium falciparum. Journal of medicinal chemistry, 1994, May-13, Volume: 37, Issue:10 Topics: Aminoacridines; Animals; Antimalarials; Cell Division; Cells, Cultured; Drug Resistance; Erythrocytes; Humans; Plasmodium falciparum; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1994
Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile. Journal of natural products, 1993, Volume: 56, Issue:8 Topics: Alkaloids; Amaryllidaceae Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Magnetic Resonance Spectroscopy; Phenanthridines; Plants, Medicinal; Plasmodium falciparum; Spectrophotometry, Ultraviolet	1993
Cytotoxic and antimalarial alkaloids from the tubers of Stephania pierrei. Journal of natural products, 1993, Volume: 56, Issue:9 Topics: Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Aporphines; Drug Screening Assays, Antitumor; Glucosides; Isoquinolines; Magnetic Resonance Spectroscopy; Molecular Weight; Plants, Medicinal; Plasmodium falciparum; Species Specificity	1993
A new antimalarial quassinoid from Simaba guianensis. Journal of natural products, 1993, Volume: 56, Issue:11 Topics: Animals; Antimalarials; Brazil; Bridged Bicyclo Compounds; Chromatography, Thin Layer; Glaucarubin; Magnetic Resonance Spectroscopy; Plant Extracts; Plants, Medicinal; Plasmodium falciparum; Quassins; Spectrophotometry, Ultraviolet	1993
Cytotoxic and antimalarial bisbenzylisoquinoline alkaloids from Stephania erecta. Journal of natural products, 1993, Volume: 56, Issue:1 Topics: Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Benzylisoquinolines; Cell Survival; Drug Screening Assays, Antitumor; Erythrocytes; Female; Humans; In Vitro Techniques; Male; Mice; Plants, Medicinal; Plasmodium falciparum; Thailand; Tumor Cells, Cultured	1993
Costaricine, a new antiplasmodial bisbenzylisoquinoline alkaloid from Nectandra salicifolia trunk bark. Journal of natural products, 1996, Volume: 59, Issue:6 Topics: Alkaloids; Animals; Antimalarials; Chromatography, Thin Layer; Costa Rica; Mass Spectrometry; Plants, Medicinal; Plasmodium falciparum	1996
Antimalarial activity of tropical Meliaceae extracts and gedunin derivatives. Journal of natural products, 1997, Volume: 60, Issue:4 Topics: Animals; Antimalarials; Cell Survival; Chloroquine; Drug Resistance; Humans; KB Cells; Limonins; Malaria, Falciparum; Mice; Plant Extracts; Plants, Medicinal; Plasmodium falciparum; Rats; Secosteroids; Structure-Activity Relationship	1997
In vitro and in vivo antiplasmodial activity of cryptolepine and related alkaloids from Cryptolepis sanguinolenta. Journal of natural products, 1997, Volume: 60, Issue:7 Topics: Alkaloids; Animals; Antimalarials; Humans; In Vitro Techniques; Indole Alkaloids; Indoles; Mice; Microbial Sensitivity Tests; Plants, Medicinal; Plasmodium berghei; Plasmodium falciparum; Quinolines; Spectrum Analysis	1997
Antiplasmodial and cytotoxic activity of natural bisbenzylisoquinoline alkaloids. Journal of natural products, 1999, Volume: 62, Issue:1 Topics: Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Tumor Cells, Cultured	1999
Strychnogucines A and B, two new antiplasmodial bisindole alkaloids from Strychnos icaja. Journal of natural products, 2001, Volume: 64, Issue:1 Topics: Alkaloids; Animals; Antimalarials; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plasmodium falciparum; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Strychnine	2001
Structure-activity relationships of novel anti-malarial agents. Part 2: cinnamic acid derivatives. Bioorganic & medicinal chemistry letters, 2001, Feb-12, Volume: 11, Issue:3 Topics: Animals; Antimalarials; Cinnamates; Combinatorial Chemistry Techniques; Inhibitory Concentration 50; Microbial Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship	2001
Synthesis of new artemisinin analogues from artemisinic acid modified at C-3 and C-13 and their antimalarial activity. Journal of natural products, 2001, Volume: 64, Issue:9 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Chromatography, Thin Layer; Drug Resistance, Microbial; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; KB Cells; Magnetic Resonance Spectroscopy; Molecular Structure; Plasmodium falciparum; Sesquiterpenes; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Structure-Activity Relationship	2001
Structure-activity relationships of the antimalarial agent artemisinin. 7. Direct modification of (+)-artemisinin and in vivo antimalarial screening of new, potential preclinical antimalarial candidates. Journal of medicinal chemistry, 2002, Sep-12, Volume: 45, Issue:19 Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Drug Evaluation, Preclinical; Drug Resistance; Injections, Intravenous; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship	2002
Lupeol long-chain fatty acid esters with antimalarial activity from Holarrhena floribunda. Journal of natural products, 2006, Volume: 69, Issue:1 Topics: Animals; Antimalarials; Cameroon; Erythrocytes; Fatty Acids; Holarrhena; Molecular Structure; Pentacyclic Triterpenes; Plant Bark; Plants, Medicinal; Plasmodium falciparum; Structure-Activity Relationship; Triterpenes	2006
A clinical drug library screen identifies astemizole as an antimalarial agent. Nature chemical biology, 2006, Volume: 2, Issue:8 Topics: Animals; Antimalarials; Astemizole; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance; Drug Resistance, Multiple; Humans; Mice; Plasmodium falciparum; Plasmodium yoelii	2006
Biological activities and 3D QSAR studies of a series of Delisea pulchra (cf. fimbriata) derived natural products. Journal of natural products, 2006, Volume: 69, Issue:8 Topics: Anti-Infective Agents; Antimalarials; Antineoplastic Agents; Antitubercular Agents; Furans; HIV Reverse Transcriptase; Hydrocarbons, Halogenated; Interleukin-1; Models, Molecular; Molecular Conformation; Molecular Structure; Protein Kinase C; Protein-Tyrosine Kinases; Quantitative Structure-Activity Relationship; Rhodophyta	2006
In vitro antimalarial activity of azithromycin, artesunate, and quinine in combination and correlation with clinical outcome. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Azithromycin; Clinical Trials, Phase II as Topic; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes	2007
High-throughput Plasmodium falciparum growth assay for malaria drug discovery. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2 Topics: Animals; Biological Assay; Child, Preschool; DNA, Protozoan; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Female; Humans; Indoles; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Pregnancy	2007
Assessment and continued validation of the malaria SYBR green I-based fluorescence assay for use in malaria drug screening. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Animals; Antimalarials; Benzothiazoles; Diamines; Drug Evaluation, Preclinical; Erythrocytes; Fluorescent Dyes; Humans; Hypoxanthine; Organic Chemicals; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Reproducibility of Results; Sensitivity and Specificity	2007
Synthesis and heme-binding correlation with antimalarial activity of 3,6-bis-(omega-N,N-diethylaminoamyloxy)-4,5-difluoroxanthone. Bioorganic & medicinal chemistry, 2008, Feb-01, Volume: 16, Issue:3 Topics: Animals; Antimalarials; Fluorine; Heme; Magnetic Resonance Spectroscopy; Molecular Structure; Plasmodium falciparum; Spectrophotometry; Structure-Activity Relationship; Xanthones	2008
Differential effects of quinoline antimalarials on endocytosis in Plasmodium falciparum. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5 Topics: Amodiaquine; Animals; Antimalarials; Blotting, Western; Chloroquine; Endocytosis; Erythrocytes; Hemoglobins; Humans; Mefloquine; Peroxidase; Phenanthrenes; Plasmodium falciparum; Protein Binding; Protozoan Proteins; Quinolines	2008
Synthesis and in vitro antitubercular activity of a series of quinoline derivatives. Bioorganic & medicinal chemistry, 2009, Feb-15, Volume: 17, Issue:4 Topics: Antitubercular Agents; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Quinolines; Structure-Activity Relationship; Tuberculosis, Multidrug-Resistant	2009
Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century. Journal of medicinal chemistry, 2009, Mar-12, Volume: 52, Issue:5 Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Benzylamines; Cytochrome P-450 Enzyme Inhibitors; Dogs; Drug Evaluation, Preclinical; Drug Resistance; Female; Haplorhini; Heme; Humans; Malaria; Mice; Models, Molecular; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Rats; Structure-Activity Relationship	2009
Dynamics of malaria drug resistance patterns in the Amazon basin region following changes in Peruvian national treatment policy for uncomplicated malaria. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5 Topics: Animals; Antimalarials; Drug Resistance; Genotype; Haplotypes; Health Policy; Humans; Malaria, Falciparum; Microsatellite Repeats; Mutation; Parasitic Sensitivity Tests; Peru; Plasmodium falciparum; Protozoan Proteins	2009
Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine. Journal of medicinal chemistry, 2009, Apr-09, Volume: 52, Issue:7 Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Cell Survival; Chloroquine; Dogs; Drug Resistance; Female; Haplorhini; Hepatocytes; Humans; In Vitro Techniques; Malaria; Male; Mice; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Rats; Rats, Wistar; Structure-Activity Relationship	2009
Atorvastatin is a promising partner for antimalarial drugs in treatment of Plasmodium falciparum malaria. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6 Topics: Animals; Antimalarials; Atorvastatin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Plasmodium falciparum; Pyrroles	2009
In vitro chemosensitization of Plasmodium falciparum to antimalarials by verapamil and probenecid. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7 Topics: Adjuvants, Pharmaceutic; Animals; Antimalarials; Parasitic Sensitivity Tests; Plasmodium falciparum; Probenecid; Verapamil	2009
Antimalarial activity of tigecycline, a novel glycylcycline antibiotic. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9 Topics: Animals; Anti-Bacterial Agents; Antimalarials; Doxycycline; Inhibitory Concentration 50; Minocycline; Parasitic Sensitivity Tests; Plasmodium falciparum; Tetracycline; Tetracyclines; Tigecycline	2009
Plasmodium falciparum drug resistance in Madagascar: facing the spread of unusual pfdhfr and pfmdr-1 haplotypes and the decrease of dihydroartemisinin susceptibility. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:11 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Haplotypes; Madagascar; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase	2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Increased glycolytic ATP synthesis is associated with tafenoquine resistance in Leishmania major. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:3 Topics: Adenosine Triphosphate; Aminoquinolines; Antiprotozoal Agents; Drug Resistance; Glycolysis; Leishmania major; Pyruvate Kinase	2011
Synthesis of isocryptolepine analogues and their structure-activity relationship studies as antiplasmodial and antiproliferative agents. European journal of medicinal chemistry, 2015, Apr-13, Volume: 94 Topics: Antimalarials; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Chemistry Techniques, Synthetic; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; Indole Alkaloids; Plasmodium falciparum; Quinolines; Structure-Activity Relationship	2015