mefloquine carboxylic acid has been researched along with mefloquine in 10 studies
| Studies (mefloquine carboxylic acid) | Trials (mefloquine carboxylic acid) | Recent Studies (post-2010) (mefloquine carboxylic acid) | Studies (mefloquine) | Trials (mefloquine) | Recent Studies (post-2010) (mefloquine) |
|---|---|---|---|---|---|
| 16 | 1 | 3 | 2,212 | 342 | 560 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bergqvist, Y; Hellgren, U; Kihamia, CM; Rombo, L | 1 |
| Bergqvist, Y; Churchill, FC; Eckerbom, S; Larsson, N | 1 |
| Bergqvist, Y; Churchill, FC; Hellgren, U | 1 |
| Crevoisier, CA; Fischer, M; Graf, H; Joseph, I | 1 |
| al Kabbani, J; Berggren Palme, I; Bergqvist, Y; Krysén, B; Rombo, L | 1 |
| Bonato, PS; Magalhães, IR | 1 |
| Franzblau, SG; Huang, Q; Kozikowski, AP; Mao, J; Pieroni, M; van Breemen, RB; Wan, B; Wang, Y; Yuan, H | 1 |
| Bitter, A; Burk, O; Gil, JP; Nüssler, AK; Piedade, R; Schwab, M; Traub, S | 1 |
| Akerey-Diop, D; Basra, A; Geditz, M; Gonzalez, R; Hofmann, U; Kerb, R; Kremsner, PG; Lehr, T; Mackanga, JR; Matsiegui, PB; Menendez, C; Mombo-Ngoma, G; Ramharter, M; Schwab, M; Wojtyniak, JG; Würbel, H; Zoleko Manego, R | 1 |
| de Sena, LWP; Ferreira, MVD; Rivera, JGB; Vieira, JLF | 1 |
1 trial(s) available for mefloquine carboxylic acid and mefloquine
| Article | Year |
|---|---|
Influence of hemodialysis on plasma concentration-time profiles of mefloquine in two patients with end-stage renal disease: a prophylactic drug monitoring study.
Topics: Africa, Eastern; Aged; Chromatography, High Pressure Liquid; Female; Humans; Kidney Failure, Chronic; Malaria; Male; Mefloquine; Renal Dialysis; Spectrophotometry, Ultraviolet; Travel | 1995 |
9 other study(ies) available for mefloquine carboxylic acid and mefloquine
| Article | Year |
|---|---|
Standard and reduced doses of mefloquine for treatment of Plasmodium falciparum in Tanzania: whole blood concentrations in relation to adverse reactions, in vivo response, and in vitro susceptibility.
Topics: Adolescent; Animals; Child; Chloroquine; Drug Administration Schedule; Humans; Malaria; Mefloquine; Plasmodium falciparum; Tanzania | 1991 |
High-performance liquid chromatographic separation and extraction investigation for the simultaneous determination of mefloquine and its carboxylic acid metabolite.
Topics: Amines; Antimalarials; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Mefloquine; Particle Size; Quinolines; Solvents; Spectrophotometry, Ultraviolet | 1988 |
High-performance liquid chromatographic assay for the simultaneous monitoring of mefloquine and its acid metabolite in biological samples using protein precipitation and ion-pair extraction.
Topics: Animals; Antimalarials; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydrogen-Ion Concentration; Indicators and Reagents; Male; Mefloquine; Proteins; Quinolines; Saimiri | 1988 |
High-performance liquid chromatographic method for the simultaneous determination of mefloquine and its carboxylic metabolite in 100-microliters capillary blood samples dried on paper.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Humans; Mefloquine; Paper; Reference Standards; Spectrophotometry, Ultraviolet; Temperature | 1993 |
Two-step liquid-phase microextraction and high-performance liquid chromatography for the simultaneous analysis of the enantiomers of mefloquine and its main metabolite carboxymefloquine in plasma.
Topics: Chemical Fractionation; Chromatography, High Pressure Liquid; Mefloquine; Molecular Structure; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism; Time Factors | 2009 |
From serendipity to rational antituberculosis drug discovery of mefloquine-isoxazole carboxylic acid esters.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Drug Discovery; Esters; Female; Humans; Isoxazoles; Mefloquine; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Mycobacterium tuberculosis; Vero Cells | 2009 |
Carboxymefloquine, the major metabolite of the antimalarial drug mefloquine, induces drug-metabolizing enzyme and transporter expression by activation of pregnane X receptor.
Topics: Animals; Antimalarials; Biological Transport; Cell Line; Chlorocebus aethiops; COS Cells; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2B6 Inducers; Drug Interactions; Drug Resistance; Hep G2 Cells; Hepatocytes; Humans; Malaria; Mefloquine; Pregnane X Receptor; Protein Binding; Receptors, Steroid; RNA Interference; RNA, Small Interfering | 2015 |
Population Pharmacokinetics of Mefloquine Intermittent Preventive Treatment for Malaria in Pregnancy in Gabon.
Topics: Adolescent; Adult; Antimalarials; Drug Combinations; Female; Humans; Malaria; Mefloquine; Pharmacokinetics; Plasmodium falciparum; Pregnancy; Pyrimethamine; Sulfadoxine; Young Adult | 2019 |
Association of Lipid Levels with Mefloquine and Carboxy-Mefloquine Concentrations in Patients with Uncomplicated Falciparum Malaria.
Topics: Adult; Antimalarials; Artesunate; Biotransformation; Brazil; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Drug Therapy, Combination; Erythrocytes; Humans; Malaria, Falciparum; Male; Mefloquine; Plasmodium falciparum; Severity of Illness Index; Triglycerides | 2020 |