mefloquine has been researched along with quinine in 276 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 63 (22.83) | 18.7374 |
| 1990's | 100 (36.23) | 18.2507 |
| 2000's | 62 (22.46) | 29.6817 |
| 2010's | 47 (17.03) | 24.3611 |
| 2020's | 4 (1.45) | 2.80 |
| Authors | Studies |
|---|---|
| Chibale, K; Franzblau, SG; Gut, J; Little, S; Rosenthal, PJ; Tukulula, M; Wan, B | 1 |
| Fidock, DA; Flannery, EL; Winzeler, EA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Feng, LS; Gao, C; Hu, YQ; Wu, X; Xu, L; Xu, Z; Zhang, S; Zhao, F | 1 |
| Aldrich, CC; Cui, H; Ferguson, DM; Guo, K; Larson, P; Li, Y; Liu, X; Ma, C; Sheng, L; Wang, S; Wang, X; Zeng, Y; Zhang, G; Zhang, J; Zou, X | 1 |
| Bane, CE; Black, C; Butler, K; Caridha, D; Cooper, RA; Dodean, RA; Gaona, H; Gaynor-Ohnstad, L; Huezo, SJ; Kancharla, P; Kelly, JX; Kreishman-Deitrick, M; Leed, SE; Li, Q; Li, Y; Lin, H; Luong, TL; Marcsisin, S; Melendez, V; Nolan, C; Olmeda, R; Potter, B; Pou, S; Rasmussen, SA; Read, L; Riscoe, MK; Roncal, N; Sciotti, RJ; Smilkstein, MJ; Sousa, J; Stephens, MT; Tan, JC; Vesely, B; Vuong, C; Winter, RW; Xie, L; Zeng, Q; Zhang, J; Zhang, P | 1 |
| Chellappan, DK; Collet, TA; Dighe, SN; Dua, K; Ekwudu, O; Katavic, PL | 1 |
| Agnamey, P; Azas, N; Cohen, A; Damiani, C; Dassonville-Klimpt, A; Dormoi, J; Guillon, J; Marchivie, M; Mullié, C; Pradines, B; Schneider, J; Sonnet, P; Taudon, N; Tisnerat, C; Totet, A | 1 |
| Ghosh, SK; Sharma, VP; Yadav, RS | 1 |
| Badoual, J | 1 |
| Brasseur, P; Druilhe, P; Kouamouo, J; Moyou, RS | 1 |
| Hla, KK; Shwe, T | 1 |
| Than, M; Thwe, Y; Win, K | 1 |
| Fadat, G; Gardon, J; Gazin, P; Hengy, C; Jambou, R; Louis, FJ; Louis, JP; Trebucq, A | 1 |
| Bustos, MD; Ciceron, L; Danis, M; Gay, F; Gentilini, M; Pichet, C; Rojas-Rivero, L | 1 |
| Brasseur, P; Druilhe, P; Kouamouo, J; Moyou-Somo, R | 1 |
| Shah, PM | 1 |
| Back, DJ; Bangchang, KN; Karbwang, J | 1 |
| Salako, LA; Sowunmi, A | 1 |
| Basco, LK; Bouchaud, O; Coulaud, JP; Farinotti, R; Gillotin, C; Gimenez, F; Le Bras, J; Rabenjarson, E; Ringwald, P | 1 |
| Jariya, P; Mankalanond, K; Tiewchaloren, S | 1 |
| Baudon, D; Cordoliani, G; Da Conceicao, S; Delolme, H; Doury, JC; Hovette, P; Lecamus, JL; Martet, G; Raphenon, G; Touze, JE | 1 |
| Allaouchiche, B; Biron, F; Boibieux, A; Gaussorgues, P; Gerard-Boncompain, M; Peyramond, D; Robert, D; Salord, F; Sirodot, M | 1 |
| Trigg, PI | 1 |
| Carme, B | 1 |
| Baird, JK; Bangs, MJ; Basri, H; Jones, TR; Ritonga, A | 1 |
| Brasseur, P; Druilhe, P; Kouamouo, J | 1 |
| Abua, JU; Lege-Oguntoye, L; Ogala, WN; Olurinola, PF; Slotboom, AB; Werblinska, B | 1 |
| Sugioka, Y; Suzuki, M | 1 |
| Brandicourt, O; Carme, B; Gay, F; Gentilini, M; Turk, P | 1 |
| Bourdeau, EF; Childs, GE; Milhous, WK; Pang, L; Wimonwattratee, T | 1 |
| Bygbjerg, IC; Magnussen, P | 1 |
| Le Bras, M; Mazaudier, E; Raccurt, CP; Ripert, C; Schmitt, A | 1 |
| Chakrabarti, NK; Nagaraj, C; Narasimham, MV | 1 |
| Bunnag, D; Harinasuta, T; Lasserre, R | 1 |
| Jeandel, P; Touze, JE | 1 |
| Berger, M; Beytout, J; Cambon, M; Rey, M; Ringwald, P | 1 |
| Hall, AP; Malin, AS | 1 |
| Brandicourt, O; Carme, B; Gay, F; Gentilini, M; Le Bras, J; Mbitsi, A; Moudzeo, H; Ndounga, M; Sathounkazi, C | 1 |
| Le Bras, J; Malhotra, K; Salmon, D; Vilde, JL | 1 |
| De Boeck, H; Maguire, PA; Sherman, IW; Zidovetzki, R | 1 |
| Andersen, BJ; Bygbjerg, IC; Pedersen, BK; Theander, TG | 1 |
| Abissègue, B; Garrigue, G; Gazin, P; Gelas, H; Ghogomu, NA; Hengy, C; Jambou, R; Kouka-Bemba, D; Le Bras, J | 1 |
| Andriamangatiana-Rason, MD; Coulanges, P; Deloron, P; Lepers, JP; Ramanamirija, JA | 1 |
| Dutta, GP; Kazim, M; Maitra, SC; Saxena, R | 1 |
| Atiya, A; De Boeck, H; Sherman, IW; Zidovetzki, R | 1 |
| Bunnag, D; Chittamas, S; Harinasuta, T; Looareesuwan, S; White, NJ | 1 |
| Lwin, M; Zaw, M | 1 |
| Bonnevie, O; Cordoliani, G; Dedet, JP; Germanetto, P; Le Bras, J | 1 |
| Denis, MB; Giboda, M | 1 |
| Brandicourt, O; Brasseur, P; Druilhe, P; Kouamouo, J; Moyou-Somo, R | 1 |
| Brubaker, G; Draper, CC; Hills, M; Kilimali, VA | 1 |
| Druilhe, P; Gentilini, M; Stahel, E | 1 |
| Bouchara, JP; Chabasse, D; De Gentile, L; Le Bras, J; Ligny, C; Rialland, X | 1 |
| Rolfe, M | 1 |
| Go, ML; Lee, HS | 1 |
| Childs, GE; Pooyindee, N; Wimonwattrawatee, T | 1 |
| Boudreau, EF; Chen, C; Childs, GE; Häusler, B; Milhous, W; Pooyindee, N; Wimonwattrawatee, T | 1 |
| Bugilimfura, L; Deloron, P; Neill, M; Ntilivamunda, A; Sexton, JD | 1 |
| Ginsburg, H; Krugliak, M | 1 |
| Björkman, A; Willcox, M | 1 |
| Buck, RL; Long, GW; Ranoa, CP; Sangalang, RP; Sy, N; Watt, G | 1 |
| Myint, PT; Shwe, T | 1 |
| Brockelman, CR; Bunnag, D; Satayavivad, J; Tan-ariya, P; Wongsawatkul, O | 1 |
| Biaud, JM; Calmel, MB; Clausse, JL; Deloron, P; Hatin, I; Le Bras, J; Marchais, H; Porte, J; Ramanamirija, JA; Simon, F | 1 |
| Briand, MC; Buil, A; Lataste, P; Le Bras, M; Nlend, A; Ragnaud, JC; Ripert, C; Roue, R; Soubiran, G; Wone, C | 1 |
| Bendtzen, K; Bygbjerg, IC; Svenson, M; Theander, TG | 1 |
| Doberstyn, EB; Gaüzère, BA; Meek, SR; Nordlander, E; Phuphaisan, S; Thanapanich, C | 1 |
| Brandicourt, O; Brasseur, P; Danis, M; Druilhe, P; Kouamouo, J; Moyou, SR | 1 |
| Ginsburg, H; Krugliak, M; Zarchin, S | 1 |
| Denis, MB | 1 |
| Andersen, BJ; Bygbjerg, IC; Flachs, H; Jepsen, S; Larsen, PB; Theander, TG | 1 |
| Bonanni, LC; Geary, TG; Ginsburg, H; Jensen, JB | 1 |
| Rooney, W; Suebsaeng, L; Wernsdorfer, WH | 1 |
| Bhattacharya, DN; Hall, AP | 1 |
| Brandicourt, O; Brasseur, P; Danis, M; Diouf, F; Druilhe, P; Gay, F; Kombila, MY; Kouamouo, J; Moyou, RS; Richard-Lenoble, D | 1 |
| Delacollette, C; Hendrix, L; Mpungu, MT; Ngimbi, NP; Wery, M | 1 |
| Dutta, GP; Kazim, M; Saxena, R | 1 |
| Boudreau, EF; Pang, LW; Pavanand, K; Webster, HK; Yongvanitchit, K | 1 |
| Alcantara, AK; Buck, RL; Rodriguez, CS; Smrkovski, LL; Uylangco, CV | 1 |
| Peters, W | 2 |
| Canfield, CJ; Cosgriff, TM; Pamplin, CL; Willet, GP | 1 |
| de Oliveira, RM; de Souza, JM; de Souza, SD; Roulet, H; Sheth, UK | 1 |
| Gluzman, IY; Krogstad, DJ; Schlesinger, PH | 1 |
| Delacollette, C; Gregory, MG; Mpungu, MT; Ngimbi, NP; Wery, M | 1 |
| Coulanges, P; Deloron, P; Le Bras, J; Ramanamirija, JA | 1 |
| Danis, M; Gentilini, M | 1 |
| Salako, LA | 1 |
| Demel, RA; Ginsburg, H | 1 |
| Ferrante, A; Goh, DH | 1 |
| Deloron, P; Le Bras, J | 1 |
| Beale, GH; Chutmongkonkul, M; Thaithong, S | 1 |
| Andrieu, B; Coulaud, JP; Deloron, P; Le Bras, J; Ricour, A; Savel, J | 1 |
| Prüfer, L; von Sonnenburg, F | 1 |
| Chiodini, PL; Ellis, CJ | 1 |
| Alpers, MP; Davidson, WL; Jolley, D; Knowles, G | 1 |
| Coulanges, P; Deloron, P; Dourado, HV; Hartmann, JF; Larouze, B; Le Bras, J | 1 |
| Rosário, VE; Vasconcelos, MA | 1 |
| Coulanges, P; Coulaud, JP; Deloron, P; Le Bras, J | 1 |
| Dutta, P; Fitch, CD | 1 |
| Andrieu, B; Deloron, P; Hartmann, JF; Le Bras, J | 1 |
| Fernex, M | 1 |
| Chongsuphajaisiddhi, T; Luxemburger, C; Nosten, F; Raimond, SD; White, NJ | 1 |
| Alvar, J; Amela, C; Benito, A; Molina, R; Roche, J | 1 |
| Eichenlaub, D; Jelinek, T; Löscher, T; Schelbert, P | 1 |
| Beauté-Lafitte, A; Caillard, V; Chabaud, A; Ginsburg, H; Landau, I | 1 |
| Deacon, HE; Freese, JA; Sharp, BL | 1 |
| Bangchang, KN; Harinasuta, T; Karbwang, J; Thanavibul, A; Wattanakoon, Y | 1 |
| Basco, LK; Le Bras, J; Makler, MM; Marquet, F | 1 |
| Canfield, C; Charoenlarp, P; Kyle, DE; Lasserre, R; Looareesuwan, S; Vanijanonta, S; Viravan, C; Webster, HK; Wilairatana, P | 1 |
| Yang, H; Yang, P; Yang, Y | 1 |
| Edwards, G; Ward, SA; Winstanley, PA | 1 |
| Baric, RS; Bright, P; Handy, J; Peel, SA; Yount, B | 1 |
| Aouba, A; Guiguemde, TR; Lamizana, L; Ouedraogo, JB | 1 |
| Basco, LK; Le Bras, J | 2 |
| Holfels, E; Mack, D; McAuley, J; McLeod, R; Milhous, WK | 1 |
| Fleckenstein, L; Jongsakul, K; Karnasuta, C; Loesuttiviboon, L; Ohrt, CK; Schuster, B; Shanks, GD; Watt, G | 1 |
| Basco, LK; Le Bras, J; Ramiliarisoa, O | 1 |
| Fowler, VG; Irare, SG; Lemnge, M; Malecela, E; Mashaka, M; Mhina, J; Mtoi, R; Mtui, S | 1 |
| Cowman, AF; Galatis, D; Thompson, JK | 1 |
| Birbamer, GG; Haring, HP; Kampfl, AW; Pfausler, BE; Schmutzhard, E | 1 |
| Go, ML; Lee, HS; Ngiam, TL | 1 |
| Davis, TM; Edwards, G; McGrath, CS; Pukrittayakamee, S; Supanaranond, W; Ward, SA; White, NJ | 1 |
| Baric, RS; Handy, J; Merritt, SC; Peel, SA | 1 |
| Schubarth, P | 1 |
| Davis, TM; Nagachinta, B; Pukrittayakamee, S; Supanaranond, W; White, NJ | 1 |
| Batchelor, R; Burans, JP; Iriye, C; Lobel, HO; Longer, CF; Magill, AJ; Rozmajzl, P; Sharp, TW; Smoak, B; Thornton, SA; Wallace, MR | 1 |
| Evans, SG; Havlik, I | 1 |
| Touze, JE | 1 |
| Brault, M; Delling, U; Gros, P; Ruetz, S; Schurr, E | 1 |
| Bouquety, JC; Carme, B; Gay, F; Hayette-Gorremans, MP; Ndounga, M | 1 |
| Kato, K; Matsushita, K; Nishina, M | 1 |
| Furukawa, H; Ohno, T; Shirasaka, A; Sugiyama, T | 1 |
| Bray, PG; Green, JE; Hawley, SR; Mungthin, M; Ritchie, GY; Ward, SA | 1 |
| Adak, T; Ansari, MA; Biswas, S; Devi, CU; Pillai, CR; Sharma, YD | 1 |
| Heppner, DG; Kawamoto, F; Nguyen, TD; Sookto, P; Trieu, NT; Wimonwattrawatee, T; Wongsrichanalai, C | 1 |
| Foley, M; Tilley, L | 1 |
| Croft, SL; Elueze, EI; Warhurst, DC | 1 |
| Pillans, PI; Tish, KN | 1 |
| Barguil, Y; Descamps, I; Genelle, B; Levenes, H; Monchy, D | 1 |
| Go, ML; Ngiam, TL | 1 |
| Boutes, S; Karbwang, J; Na-Bangchang, K; Riengchainam, S; Tan-ariya, P; Ubalee, R | 1 |
| Adagu, IS; Machado, RL; Miles, MA; Oliveira, SG; Póvoa, MM; Warhurst, DC | 1 |
| Doury, JC; Fusai, T; Pradines, B; Rogier, C; Tall, A; Trape, JF | 1 |
| Chene, L; Chongsuphajaisiddhi, T; Daubersies, P; Druilhe, P; Gentil, C; Langsley, G; Mellouk, S; Patarapotikul, J | 1 |
| Kremsner, PG; Philipps, J; Radloff, PD; Wernsdorfer, W | 1 |
| Milhous, WK; Pang, L; Silveira, MS; Wirth, DF; Zalis, MG | 1 |
| Coulibaly, SO; Dutheil, Y; Guiguemdé, TR; Ouédraogo, JB; Tall, F; Tinto, H; Traoré, B; Zampa, H | 1 |
| Clerinx, J; Colebunders, R; Coppens, G; Depraetere, K; Peetermans, WE; Schroyens, W; Van den Ende, J; Van den Enden, E; Van Gompel, A; Van Haegenborgh, T; Verstraeten, T | 1 |
| Hatz, C; Markwalder, K | 1 |
| Ang, HH; Chan, KL; Mak, JW | 1 |
| Khusmith, S; Kitjaroentham, A; Laothavorn, J; Na-Bangchang, K; Thammapalerd, N | 1 |
| Cho, T; Chongsuphajaisiddhi, T; Hkirijaroen, L; McGready, R; Nosten, F; Simpson, J; White, NJ | 1 |
| Bourgeade, A; Delmont, J | 1 |
| Burgel, PR; Camara, P; Hovette, P; Klotz, F; Mbaye, PS; Sane, M | 1 |
| Chongsuphajaisiddhi, T; Luxemburger, C; Nosten, F; Phaipun, L; Price, R; Simpson, JA; ter Kuile, F; van Vugt, M; White, NJ | 1 |
| Suzuki, M | 1 |
| Buckling, A; Crooks, L; Read, A | 1 |
| Bray, PG; Mungthin, M; Ward, SA | 1 |
| Danis, M; Delhaes, L; Gay, F; Lazaro, JE; Thellier, M | 1 |
| Angkasekwinai, P; Buranakiti, A; Chaiyaroj, SC; Cowman, AF; Looressuwan, S | 1 |
| Duraisingh, MT; Jones, P; Pinder, M; Sambou, I; von Seidlein, L; Warhurst, DC | 1 |
| Caruana, SR; Cowman, AF; Kirk, K; Reed, MB; Saliba, KJ | 1 |
| McGready, R; Nosten, F | 1 |
| Makonnen, E; Mengesha, T | 1 |
| Karbwang, J; Na-Bangchang, K; Riengchainam, S; Shrestha, SB; Tan-Ariya, P; Thanavibul, A | 1 |
| Behrens, RH; Day, JH; Evans, MR | 1 |
| Hombhanje, FW | 1 |
| Bachhawat, K; Surolia, A; Surolia, N; Thomas, CJ | 1 |
| Ashcroft, FM; Clark, A; Davis, TM; Gribble, FM; Higham, CE | 1 |
| Brandts, C; Kremsner, PG; Philipps, J; Schwenke, A; Wernsdorfer, WH; Winkler, S | 1 |
| Brasseur, P; Cuzin-Ouattara, N; Druilhe, P; Moreno, A; Nebie, I; Sanon, S | 1 |
| Franco, P; Lämmerhofer, M; Lindner, W; Petracs, M; Zarbl, E | 1 |
| Kollaritsch, H; Krudsood, S; Looareesuwan, S; Noedl, H; Viriyavejakul, P; Wernsdorfer, WH; Wiedermann, G; Wilairatana, P | 1 |
| Bounyasong, S | 1 |
| Björkman, A; Gupta, S; Thapar, MM; Wernsdorfer, WH | 1 |
| Karle, IL; Karle, JM | 1 |
| Belsare, H; Patel, AB | 1 |
| Bedos, JP; Bruneel, F; Danis, M; Gachot, B; Regnier, B; Vachon, F; Wolff, M | 1 |
| Fidock, DA; Sidhu, AB; Verdier-Pinard, D | 1 |
| Agrawal, R; Dutta, GP; Jain, SK; Shukla, OP; Tekwani, BL; Tripathi, R | 1 |
| Alberti, C; Bédos, JP; Bruneel, F; Chevret, S; Durand, R; Hocqueloux, L; Le Bras, J; Régnier, B; Vachon, F; Wolff, M | 1 |
| Cravo, P; do Rosário, VE; Gil, JP; Lopes, D; Nogueira, F; Rungsihirunrat, K; Seugorn, A | 1 |
| Atteke, C; Aubouy, A; Bakary, M; Deloron, P; Lébibi, J; Ndong, JM | 1 |
| Huang, K; Liao, M; Liu, D; Yang, H; Yang, P; Yang, Y; Zhang, C | 1 |
| Gao, BH; Huang, KG; Yang, HL | 1 |
| Bouchaud, O; Durand, R; Godineau, N; Jezic, Z; Keundjian, A; Le Bras, J; Pradines, B; Ralaimazava, P | 1 |
| Jambou, R; Randrianarijaona, A; Randrianarivelojosia, M; Randrianasolo, L; Ratsimbasoa, A | 1 |
| Faiz, MA; Hossain, MA; Miller, RS; Noedl, H; Pang, LW; Rahman, MR; Samad, R; Wongsrichanalai, C; Yunus, EB | 1 |
| Ariey, F; Duchemin, JB; Harisoa, JL; Mauclere, P; Pietra, V; Rabarijaona, LP; Raharimalala, LA; Rakotomanana, F; Ranaivo, L; Randrianarivelojosia, M; Robert, V | 1 |
| Nakajima, Y | 1 |
| Hoelscher, M; Löscher, T | 1 |
| Munasinghe, A; Myrick, A; Patankar, S; Wirth, DF | 1 |
| Ciach, M; Crandall, I; Kain, KC; Zong, K | 1 |
| Rakotoson, JD; Randremanana, RV; Randriamanantena, A; Randrianarivelojosia, M; Randrianasolo, L; Ratsimbasoa, A | 1 |
| Alecrim, WD; Daniel-Ribeiro, CT; Martínez-Espinosa, FE | 1 |
| Brown, ML; Geyer, JA; Terrell, JC; Trotta, RF | 1 |
| Aloisi, GG; Barbafina, A; Canton, M; Dall'Acqua, F; Elisei, F; Facciolo, L; Latterini, L; Viola, G | 1 |
| Garcia, C; Gerena, L; Huaman, MC; Kanbara, H; Long, TT; Magill, AJ; Nakazawa, S; Roncal, N; Solari, L | 1 |
| Chibale, K; Gut, J; Lehman, J; Musonda, CC; Rosenthal, PJ; Taylor, D | 1 |
| Majori, G | 1 |
| Emerson, LR; Kuchler, K; Skillman, BC; Wirth, DF; Wolfger, H | 1 |
| Chim, P; Denis, MB; Fandeur, T; Lim, C; Lim, P; Nemh, S; Poravuth, Y; Seila, S; Sem, R; Socheat, D; Tsuyuoka, R | 1 |
| Bisoffi, Z; Gaiera, G; Gregis, G; Gulletta, M; Marocco, S; Matteelli, A; Saleri, N; Scolari, C; Tedoldi, S; Visonà, R | 1 |
| Adams, B; Elandalloussi, LM; Smith, PJ | 1 |
| Baird, JK | 1 |
| Bangchang, KN; Chaijaroenkul, W; Mungthin, M; Ward, SA | 1 |
| Fidock, DA; Sidhu, AB; Valderramos, SG | 1 |
| Krishna, S; Woodrow, CJ | 1 |
| Chirouze, C; Créantor, C; Faucher, JF; Hoen, B; Hustache-Mathieu, L; Millon, L | 1 |
| Faragalla, IA; Mohamadani, AA; Nour, BY; Saeed, OK | 1 |
| Fidock, DA; Krishna, S; Sidhu, AB; Uhlemann, AC; Valderramos, JC; Valderramos, SG | 1 |
| Klitgaard, H; Margineanu, DG | 1 |
| Aydin, K; Ergüven, S; Ozkaya, G; Unal, S; Yildirim, T | 1 |
| Congpuong, K; Na-Bangchang, K | 1 |
| Deharo, E; Garavito, G; Maurel, S; Monje, MC; Nepveu, F; Valentin, A | 1 |
| Lochner, M; Lummis, SC; Thompson, AJ | 1 |
| Abuaku, B; Duah, NO; Koram, KA; Quashie, NB | 1 |
| Andrianantenaina, HB; Ariey, F; Domarle, O; Randrianarivelojosia, M; Rason, MA; Raveloson, A | 1 |
| Burgner, D; Cherian, S | 1 |
| Adehossi, E; Brouqui, P; Delmont, J; Parola, P; Ranque, S | 1 |
| Nyunt, MM; Plowe, CV | 1 |
| Stepniewska, K; White, NJ | 1 |
| Lummis, SC; Thompson, AJ | 1 |
| Ahmadi, M; El-Bahnasawy, M; Gouda, H; Ibrahim, A; Shahat, SA; Zaher, T | 1 |
| Chaijaroenkul, W; Harnyuttanakorn, P; Mungthin, M; Na Bangchang, K; Suwandittakul, N | 1 |
| Chaijaroenkul, W; Na-Bangchang, K; Wisedpanichkij, R | 1 |
| Akkoçlu, G; Cevikel, N; Kirakli, C; Köse, S; Kuzucu, L; Ozensoy Töz, S | 1 |
| Ariey, F; Beck, HP; Bouth, DM; Chim, P; Chy, S; Coppee, JY; Duong, S; Fandeur, T; Genton, B; Gobert, JG; Khim, N; Kim, S; Le Bras, J; Lim, P; Mercereau-Puijalon, O; Nhem, S; Ringwald, P; Rogers, WO; Sem, R; Wongsrichanalai, C; Yi, P | 1 |
| Borrmann, S; Kiara, SM; Mwai, L; Nzila, A; Ochola, LI; Ohuma, E; Okombo, J; Pole, L; Rono, J | 1 |
| Lekostaj, JK; Pleeter, P; Roepe, PD | 1 |
| Ariey, F; Beck, HP; Decosterd, LA; Duong, S; Genton, B; Hodel, EM; Mercier, T; Olliaro, P; Zanolari, B | 1 |
| Puri, SK; Singh, S; Srivastava, K; Srivastava, M; Srivastava, RK | 1 |
| Congpuong, K; Hüttinger, F; Satimai, W; Wernsdorfer, G; Wernsdorfer, WH; Wiedermann, U | 1 |
| Kimura, M; Kinoshita, A; Kotaki, H; Yamada, H | 1 |
| Carvalho, LJ; Clemmer, L; Frangos, JA; Martins, YC; Zanini, GM | 1 |
| Assi, SB; Basco, LK; Bla, KB; Djaman, AJ; Koné, M; Mazabraud, A; Yavo, W | 1 |
| Amalvict, R; Baret, E; Briolant, S; Charras, S; Feraud, M; Henry, M; Huyghues des Etages, E; Pascual, A; Pradines, B; Rogier, C | 1 |
| Chin, LC; Fong, MY; Lau, YL; Noraishah, MA; Rohela, M; Tan, LH | 1 |
| Cozens, S; Dow, GS; Gettayacamin, M; Hansukjariya, P; Imerbsin, R; Kenworthy, D; Komcharoen, S; Kyle, D; Milhous, W; Miller, A; Ohrt, C; Sattabongkot, J; Veazey, J | 1 |
| Ensom, MH; Wilby, KJ | 1 |
| Moreira-Campos, LM; Nogueira, FH; Pianetti, GA; Santos, RL | 1 |
| Kittikool, D; Sibmooh, N; Srihirun, S; Tangnitipong, S; Thaptimthong, T; Udomsangpetch, R; Unchern, S | 1 |
| Berger, F; Bertani, S; Bouchier, C; Ekala, MT; Legrand, E; Mercereau-Puijalon, O; Meynard, JB; Musset, L; Péneau, J; Volney, B; Yrinesi, J | 1 |
| Garner, P; Gelband, H; Graves, PM | 3 |
| Beeson, JG; Goodman, CD; Langer, C; McFadden, GI; Wilson, DW | 1 |
| Dwivedi, H; Pandey, SK; Rizvi, A; Saxena, JK; Tripathi, R | 1 |
| Cooksey, R; Dahlström, S; Fairhurst, RM; Flegg, JA; Guerin, PJ; Johnson, JD; Le Bras, J; Le Nagard, H; Lim, P; Ménard, D; Mentré, F; Murillo, C; Musset, L; Noedl, H; Nosten, F; Nsobya, SL; Pradines, B; Quashie, NB; Sibley, CH; Sinou, V; Sriprawat, K; Woodrow, CJ | 1 |
| Dondorp, AM; Faiz, MA; Hien, TT; Mokuolu, OA; Pukrittayakamee, S; White, NJ | 1 |
| Abdi, AI; Kiara, SM; Mwai, L; Nzila, A; Ochola-Oyier, LI; Okombo, J; Pole, L; Sutherland, CJ | 1 |
| Aubouy, A; Dahlström, S; Deloron, P; Ezinmègnon, S; Faucher, JF; Houzé, P; Houzé, S; Kendjo, E; Le Bras, J; Maïga-Ascofaré, O; Massougbodji, A; Wakpo, A | 1 |
| Chaijaroenkul, W; Muhamad, P; Na-Bangchang, K; Phompradit, P; Wisedpanichkij, R | 1 |
| Arboleda, M; Blair, S; Fernández, D; Garavito, G; Pabón, A; Segura, C | 1 |
| Baret, E; Bercion, R; Camara, C; Diatta, B; Diémé, Y; Fall, B; Fall, KB; Fall, M; Mbaye, PS; Nakoulima, A; Pascual, A; Pradines, B; Wade, B; Wurtz, N | 1 |
| de Villiers, KA; Gildenhuys, J; Kuter, D; le Roex, T; Müller, R; Sammy, CJ; Streltsov, VA | 1 |
| Huupponen, J; Lauri, SE; Molchanova, SM; Taira, T | 1 |
| Amalvict, R; Benoit, N; Diatta, B; Diawara, S; Diémé, Y; Fall, B; Fall, M; Gendrot, M; Madamet, M; Nakoulima, A; Pradines, B; Wade, B; Wade, KA | 1 |
| Muhamad, P; Na-Bangchang, K; Phompradit, P; Thiengsusuk, A | 1 |
| Amalvict, R; Benoit, N; Briolant, S; Diatta, B; Diawara, S; Diémé, Y; Fall, B; Fall, M; Gendrot, M; Kounta, MB; Madamet, M; Nakoulima, A; Pradines, B; Wade, B; Wade, KA | 1 |
| Choi, L; Garner, P; Gelband, H; Graves, PM | 1 |
| Avery, SV; Islahudin, F; Lakhani, DH; Tindall, SM; Ting, KN; Vallières, C | 1 |
| Agarwal, P; Anvikar, AR; Pillai, CR; Srivastava, K | 1 |
| Churcher, ZR; Johnson, PE; Slavkovic, S | 1 |
| Aydin-Schmidt, B; Björkman, A; Di Santi, S; Inoue, J; Islam, A; Jovel, I; Mårtensson, A; Morris, U; Segurado, AC | 1 |
| Bozdech, Z; Chen, D; Dai, L; Dziekan, JM; Larsson, A; Nordlund, P; Prabhu, N; Sobota, RM; Wirjanata, G; Yu, H | 1 |
| Anvikar, AR; Ashley, EA; Chandramohan, D; Cohee, LM; D'Alessandro, U; Genton, B; Gilder, ME; Guérin, PJ; Juma, E; Kalilani-Phiri, L; Kennon, K; Kuepfer, I; Laufer, MK; Lwin, KM; Mansoor, R; McGready, R; Meshnick, SR; Mosha, D; Mwapasa, V; Mwebaza, N; Nambozi, M; Ndiaye, JA; Nosten, F; Nyunt, M; Ogutu, B; Parikh, S; Paw, MK; Phyo, AP; Pimanpanarak, M; Piola, P; Rijken, MJ; Saito, M; Sriprawat, K; Stepniewska, K; Tagbor, HK; Tarning, J; Tinto, H; Valéa, I; Valecha, N; White, NJ; Wiladphaingern, J | 1 |
| Bah, S; Dabitao, D; Dama, S; Diakité, M; Diakité, SAS; Doumbia, S; Doumbouya, M; Guindo, MA; Keita, B; Konaté, DS; Sangaré, M; Sanogo, I; Traoré, K | 1 |
| Anywar, DA; Auma, MA; Balikagala, B; Emoto, S; Fukuda, N; Hashimoto, M; Hirai, M; Horii, T; Ikeda, M; Kataoka, M; Katuro, OT; Kimura, E; Mita, T; Mori, T; Obwoya, PS; Odongo-Aginya, EI; Ogwang, M; Opio, W; Palacpac, NMQ; Sakurai-Yatsushiro, M; Sekihara, M; Tachibana, SI; Yamauchi, M; Yatsushiro, S | 1 |
28 review(s) available for mefloquine and quinine
| Article | Year |
|---|---|
Using genetic methods to define the targets of compounds with antimalarial activity.
Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum | 2013 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Quinoline hybrids and their antiplasmodial and antimalarial activities.
Topics: Antimalarials; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines | 2017 |
Recent update on anti-dengue drug discovery.
Topics: Animals; Antiviral Agents; Biological Products; Cell Line, Tumor; Dengue Virus; Drug Discovery; Humans; Serine Proteinase Inhibitors; Viral Nonstructural Proteins; Virus Replication | 2019 |
The problem of drug resistance in malaria.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Humans; India; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine | 1985 |
Pharmacokinetics of antimalarial drugs: their therapeutic and toxicological implications.
Topics: Adult; Amodiaquine; Animals; Antimalarials; Child; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Microbial; Half-Life; Humans; Kinetics; Male; Mefloquine; Mice; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Quinine; Quinolines; Sulfadoxine; Sulfalene | 1985 |
[Progress in immunodiagnosis and chemotherapy of protozoan infections].
Topics: Amebiasis; Animals; Antibodies; Babesiosis; Chloroquine; Drug Resistance, Microbial; Giardiasis; Humans; Leishmaniasis; Malaria; Mefloquine; Pneumocystis; Pneumonia, Pneumocystis; Primaquine; Protozoan Infections; Pyrimethamine; Quinine; Quinolines; Serologic Tests; Sulfadoxine; Tetracycline; Toxoplasmosis; Trypanosomiasis | 1983 |
New answers through chemotherapy?
Topics: Aminoquinolines; Animals; Antimalarials; Chemical Phenomena; Chemistry; Disease Models, Animal; Drug Resistance; Drug Therapy, Combination; Erythrocytes; Humans; Liver; Malaria; Mefloquine; Plasmodium; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Proguanil; Quinine; Quinolines; Research; Sesquiterpenes; Species Specificity; World Health Organization | 1984 |
Quinine toxicity when given with doxycycline and mefloquine.
Topics: Adult; Doxycycline; Drug Therapy, Combination; Hearing Disorders; Humans; Malaria, Falciparum; Male; Mefloquine; Quinine | 1994 |
Clinical pharmacokinetics in the treatment of tropical diseases. Some applications and limitations.
Topics: Chloroquine; Diethylcarbamazine; Drug Resistance; Echinococcosis; Filariasis; Humans; Malaria; Mefloquine; Pharmacokinetics; Phenanthrenes; Pyrimethamine; Quinine; Sulfadoxine; Tropical Medicine | 1994 |
[Malaria: the most important emergency in subjects returning from the tropics].
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Emergencies; Humans; Malaria; Malaria, Falciparum; Mefloquine; Plasmodium; Pyrimethamine; Quinidine; Quinine; Sulfadoxine | 1993 |
[Correct usage of amino alcohols].
Topics: Antimalarials; Clinical Protocols; Drug Administration Schedule; Drug Resistance; Humans; Malaria; Mefloquine; Phenanthrenes; Quinine | 1995 |
Quinoline antimalarials: mechanisms of action and resistance.
Topics: Animals; Antimalarials; Blood Proteins; Chloroquine; Drug Resistance; Erythrocytes; Hemoglobins; Humans; Mefloquine; Membrane Proteins; Plasmodium; Quinine; Quinolines | 1997 |
[1998 malaria therapy].
Topics: Adult; Antimalarials; Child; Drug Resistance, Multiple; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Pregnancy; Quinine; Switzerland | 1998 |
[Neurological toxicity of antifungal and antiprotozoal drugs].
Topics: Amphotericin B; Antifungal Agents; Antimalarials; Antiprotozoal Agents; Antitrichomonal Agents; Central Nervous System Diseases; Chloroquine; Humans; Mefloquine; Metronidazole; Quinine | 1999 |
Comparative efficacy and safety of chloroquine and alternative antimalarial drugs: a meta-analysis from six African countries.
Topics: Africa, Eastern; Africa, Western; Amodiaquine; Antimalarials; Chloroquine; Drug Combinations; Drug Costs; Humans; Malaria; Mefloquine; Patient Selection; Phenanthrenes; Pyrimethamine; Quinine; Safety; Sulfadoxine; Treatment Outcome | 1999 |
[Antiprotozoal drugs].
Topics: Animals; Antiprotozoal Agents; Drug Combinations; Emetine; Humans; Mefloquine; Metronidazole; Phenanthrenes; Primaquine; Protozoan Infections; Pyrimethamine; Quinine; Sulfadoxine; Tinidazole | 2003 |
[Combined antimalarial therapy using artemisinin].
Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Doxycycline; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2004 |
Effectiveness of antimalarial drugs.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Life Cycle Stages; Malaria; Mefloquine; Patient Compliance; Plasmodium; Primaquine; Pyrimethamine; Quinine; Secondary Prevention; Sulfadoxine; Treatment Failure | 2005 |
Antimalarial drugs: recent advances in molecular determinants of resistance and their clinical significance.
Topics: Africa; Amino Alcohols; Animals; Antimalarials; Artemisinins; Asia, Southeastern; Biological Transport; Calcium-Transporting ATPases; Chloroquine; Drug Resistance; Drug Resistance, Multiple; Drug Therapy, Combination; Gene Amplification; Humans; Malaria, Falciparum; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Models, Biological; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinine; Sesquiterpenes | 2006 |
Current malaria status and distribution of drug resistance in East and Southeast Asia with special focus to Thailand.
Topics: Age Factors; Animals; Antimalarials; Artemisinins; Asia, Southeastern; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium; Quinine; Sesquiterpenes; Sex Factors; Sulfadoxine | 2007 |
Pharmacokinetics of antimalarials in pregnancy: a systematic review.
Topics: Anti-Bacterial Agents; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Pyrimethamine; Quinine; Sulfadoxine | 2011 |
Primaquine for reducing Plasmodium falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2012 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Insecticide-Treated Bednets; Insecticides; Malaria; Malaria Vaccines; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Primary Prevention; Pyrimethamine; Quinine; Quinolines; Seasons; Sulfadoxine | 2014 |
Primaquine or other 8-aminoquinoline for reducing P. falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2014 |
Primaquine or other 8-aminoquinoline for reducing Plasmodium falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2015 |
Primaquine or other 8-aminoquinolines for reducing Plasmodium falciparum transmission.
Topics: Adult; Antimalarials; Artemisinins; Child; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Non-Randomized Controlled Trials as Topic; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine; Time Factors | 2018 |
Efficacy and tolerability of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a systematic review and individual patient data meta-analysis.
Topics: Amodiaquine; Anti-Bacterial Agents; Antimalarials; Artemisinins; Artesunate; Atovaquone; Clindamycin; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Pyrimethamine; Quinine; Quinolines; Sulfadoxine | 2020 |
17 trial(s) available for mefloquine and quinine
| Article | Year |
|---|---|
The effect of artemether plus mefloquine on Myanmar patients with complicated falciparum malaria.
Topics: Antimalarials; Artemether; Artemisinins; Drug Therapy, Combination; Humans; Malaria, Cerebral; Malaria, Falciparum; Mefloquine; Myanmar; Quinine; Recurrence; Sesquiterpenes; Survival Rate | 1992 |
Comparison of combinations of parenteral artemisinin derivatives plus oral mefloquine with intravenous quinine plus oral tetracycline for treating cerebral malaria.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Humans; Malaria, Cerebral; Mefloquine; Middle Aged; Prospective Studies; Quinine; Sesquiterpenes; Tetracycline | 1992 |
Evaluation of the relative efficacy of various antimalarial drugs in Nigerian children under five years of age suffering from acute uncomplicated falciparum malaria.
Topics: Acute Disease; Amodiaquine; Antimalarials; Child, Preschool; Chloroquine; Drug Administration Schedule; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Male; Mefloquine; Nigeria; Pyrimethamine; Quinine; Sulfadoxine | 1992 |
Quinine resistant falciparum malaria treated with mefloquine.
Topics: Administration, Oral; Adolescent; Adult; Animals; Body Temperature; Cross Reactions; Drug Resistance, Microbial; Humans; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Prospective Studies; Quinine | 1990 |
The effect of mefloquine-artemether compared with quinine on patients with complicated falciparum malaria.
Topics: Adult; Animals; Antimalarials; Artemether; Artemisinins; Drug Therapy, Combination; Female; Humans; Malaria; Male; Mefloquine; Plasmodium falciparum; Quinine; Quinolines; Sesquiterpenes | 1988 |
Parasitologic and clinical efficacy of 25 and 50 mg/kg of chloroquine for treatment of Plasmodium falciparum malaria in Rwandan children.
Topics: Animals; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Infant; Malaria; Male; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Rwanda | 1988 |
The effect of mefloquine-sulfadoxine-pyrimethamine vs quinine on patients with complicated falciparum malaria.
Topics: Adult; Animals; Antimalarials; Drug Combinations; Female; Humans; Malaria; Male; Mefloquine; Plasmodium falciparum; Prospective Studies; Pyrimethamine; Quinine; Quinolines; Sulfadoxine; Sulfanilamides | 1987 |
Treatment of falciparum malaria with quinne and tetracycline or combined mefloquine/sulfadoxine/pyrimethamine on the Thai-Kampuchean border.
Topics: Cambodia; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinine; Quinolines; Sulfadoxine; Sulfanilamides; Tetracycline; Thailand | 1986 |
The problem of drug resistance in malaria.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Humans; India; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine | 1985 |
An open, randomized, phase III clinical trial of mefloquine and of quinine plus sulfadoxine-pyrimethamine in the treatment of symptomatic falciparum malaria in Brazil.
Topics: Adolescent; Adult; Brazil; Clinical Trials as Topic; Drug Combinations; Humans; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Random Allocation; Sulfadoxine; Sulfanilamides | 1985 |
Oral artesunate in the treatment of uncomplicated hyperparasitemic falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Malaria, Falciparum; Male; Mefloquine; Parasitemia; Quinine; Sesquiterpenes; Time Factors; Treatment Outcome | 1995 |
Randomised trial of mefloquine-tetracycline and quinine-tetracycline for acute uncomplicated falciparum malaria.
Topics: Adolescent; Adult; Aged; Animals; Drug Administration Schedule; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinine; Tetracycline | 1994 |
Efficacy and tolerance of extended-dose halofantrine for drug-resistant falciparum malaria in Thailand.
Topics: Adult; Animals; Chi-Square Distribution; Diarrhea; Dizziness; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Tetracycline; Thailand; Vomiting | 1994 |
Pharmacokinetic and pharmacodynamic interactions of mefloquine and quinine.
Topics: Adult; Animals; Antimalarials; Cross-Over Studies; Drug Interactions; Electrocardiography; Humans; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinine | 1999 |
In vivo-in vitro model for the assessment of clinically relevant antimalarial cross-resistance.
Topics: Adult; Animals; Antimalarials; Artemisinins; Chloroquine; Cross Reactions; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Models, Biological; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Recurrence; Sesquiterpenes | 2001 |
Randomized trial of artesunate and mefloquine in comparison with quinine sulfate to treat P. falciparum malaria pregnant women.
Topics: Adult; Analysis of Variance; Antimalarials; Artemisinins; Artesunate; Female; Gestational Age; Humans; Malaria, Falciparum; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Probability; Prospective Studies; Quinine; Sesquiterpenes; Thailand; Treatment Outcome | 2001 |
Mefloquine versus quinine plus sulphalene-pyrimethamine (metakelfin) for treatment of uncomplicated imported falciparum malaria acquired in Africa.
Topics: Adult; Africa; Antimalarials; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Endpoint Determination; Female; Follow-Up Studies; Humans; Italy; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Prospective Studies; Pyrimethamine; Quinine; Sulfalene | 2005 |
232 other study(ies) available for mefloquine and quinine
| Article | Year |
|---|---|
The design, synthesis, in silico ADME profiling, antiplasmodial and antimycobacterial evaluation of new arylamino quinoline derivatives.
Topics: Aminoquinolines; Antiprotozoal Agents; Antitubercular Agents; Biological Assay; Blood-Brain Barrier; Computer Simulation; Drug Design; Erythrocytes; Humans; Inhibitory Concentration 50; Mefloquine; Microbial Sensitivity Tests; Models, Biological; Mycobacterium tuberculosis; Plasmodium falciparum; Quinine; Structure-Activity Relationship; Tetrazoles | 2012 |
A Cinchona Alkaloid Antibiotic That Appears To Target ATP Synthase in Streptococcus pneumoniae.
Topics: Anti-Bacterial Agents; Binding Sites; Cinchona Alkaloids; Drug Resistance, Microbial; Microbial Sensitivity Tests; Mitochondrial Proton-Translocating ATPases; Streptococcus pneumoniae; Structure-Activity Relationship | 2019 |
Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials.
Topics: Acridones; Animals; Antimalarials; Disease Models, Animal; Drug Discovery; Hep G2 Cells; Humans; Malaria; Mice; Plasmodium; Species Specificity; Structure-Activity Relationship | 2019 |
Design, synthesis, and characterization of novel aminoalcohol quinolines with strong in vitro antimalarial activity.
Topics: Amino Alcohols; Animals; Antimalarials; Cell Line; Cricetulus; Dose-Response Relationship, Drug; Drug Design; Ether-A-Go-Go Potassium Channels; Female; Humans; Malaria; Mice; Mice, Inbred BALB C; Microsomes, Liver; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Structure-Activity Relationship | 2022 |
Sensitivity status of Plasmodium falciparum to chloroquine, amodiaquine, quinine, mefloquine and sulfadoxine/pyrimethamine in a tribal population of District Sundargarh, Orissa.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; India; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1992 |
[Treatment of malaria in children in France].
Topics: Antimalarials; Child; Chloroquine; France; Humans; Malaria, Cerebral; Malaria, Falciparum; Mefloquine; Phenanthrenes; Quinine | 1992 |
Mefloquine resistant malaria in Cameroon and correlation with resistance to quinine.
Topics: Animals; Cameroon; Carrier State; Child; Child, Preschool; Drug Resistance; Drug Utilization; Humans; Infant; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine | 1992 |
Proposals for a new therapeutic strategy for simple Plasmodium falciparum malaria attacks in Cameroon.
Topics: Administration, Oral; Aminoquinolines; Amodiaquine; Animals; Antimalarials; Cameroon; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine | 1992 |
Mefloquine-halofantrine cross-resistance in Plasmodium falciparum induced by intermittent mefloquine pressure.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine | 1992 |
Multi-drug resistant falciparum malaria in Cameroon in 1987-1988. II. Mefloquine resistance confirmed in vivo and in vitro and its correlation with quinine resistance.
Topics: Animals; Cameroon; Child; Child, Preschool; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Plasmodium falciparum; Quinine | 1992 |
[Malaria tropica].
Topics: Anti-Bacterial Agents; Antimalarials; Doxycycline; Exchange Transfusion, Whole Blood; Humans; Malaria, Falciparum; Mefloquine; Quinine; Tetracycline | 1992 |
Mefloquine metabolism by human liver microsomes. Effect of other antimalarial drugs.
Topics: Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Humans; Ketoconazole; Kinetics; Mefloquine; Microsomes, Liver; Primaquine; Quinine | 1992 |
Type RI resistance to halofantrine in West Africa.
Topics: Animals; Antimalarials; Biological Availability; Chloroquine; Cote d'Ivoire; Drug Resistance; Follow-Up Studies; France; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Phenanthrenes; Plasmodium falciparum; Quinine; Recurrence; Travel | 1991 |
An in vitro study on mefloquine/quinine in Plasmodium falciparum malaria.
Topics: Animals; Drug Combinations; Drug Evaluation, Preclinical; Humans; Mefloquine; Plasmodium falciparum; Quinine | 1991 |
[Malaria in the republic of São Tomé and Principe. Epidemiologic evaluation and chemoresistance of P. falciparum].
Topics: Age Factors; Animals; Antimalarials; Atlantic Islands; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Seasons; Sex Factors; Splenomegaly | 1991 |
Severe falciparum malaria (21 cases).
Topics: Adolescent; Adult; Child, Preschool; Chloroquine; Exchange Transfusion, Whole Blood; Female; Humans; Infusions, Intravenous; Intensive Care Units; Malaria, Cerebral; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Quinine; Respiration, Artificial; Retrospective Studies | 1991 |
Drug use and design in the nineties.
Topics: Aminoquinolines; Amodiaquine; Antimalarials; Artemisinins; Calcium Channel Blockers; Chloroquine; Humans; Malaria; Mefloquine; Naphthoquinones; Phenanthrenes; Primaquine; Quinine; Sesquiterpenes; Sulfadoxine | 1991 |
[Prevention and treatment of malaria in expatriates living in Black Africa. Influence of chemoresistance. Investigations conducted in Brazzaville (Congo)].
Topics: Adolescent; Adult; Aged; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Congo; Drug Combinations; Drug Resistance, Microbial; Europe; Humans; Infant; Infant, Newborn; Malaria; Mefloquine; Middle Aged; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1991 |
Resistance to antimalarials by Plasmodium falciparum in Arso PIR, Irian Jaya, Indonesia.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Indonesia; Malaria; Male; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1991 |
Mefloquine-resistant malaria induced by inappropriate quinine regimens?
Topics: Animals; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium falciparum; Quinine | 1991 |
Chloroquine-resistant Plasmodium falciparum with reduced sensitivity in vitro to mefloquine and quinine in Zaria, northern Nigeria.
Topics: Animals; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Infant; Malaria; Mefloquine; Nigeria; Plasmodium falciparum; Quinine | 1991 |
The chemical basis for the ferriprotoporphyrin IX-chloroquine complex induced lipid peroxidation.
Topics: Animals; Antimalarials; Apoproteins; Benzoates; Benzoic Acid; Catalase; Chloroquine; Hemin; Hydrogen-Ion Concentration; Iron; Kinetics; Lipid Peroxidation; Liposomes; Mefloquine; Oxygen; Primaquine; Quinine; Rats; Spectrum Analysis; Superoxide Dismutase; Transferrin | 1991 |
Widespread in vitro resistance to chloroquine of Plasmodium falciparum in the Congo, 1987.
Topics: Adolescent; Animals; Child; Child, Preschool; Chloroquine; Congo; Drug Resistance; Humans; Infant; Malaria; Mefloquine; Plasmodium falciparum; Quinine; Regression Analysis | 1991 |
In vitro and clinical correlates of mefloquine resistance of Plasmodium falciparum in eastern Thailand.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Butylated Hydroxytoluene; Chloroquine; Drug Resistance; Drugs, Chinese Herbal; Mefloquine; Molecular Structure; Phenanthrenes; Plasmodium falciparum; Pyridines; Pyrimethamine; Quinine; Sesquiterpenes; Thailand | 1991 |
Treatment of Plasmodium falciparum malaria with mefloquine alone or in combination with i.v. quinine at the Department of Communicable and Tropical Diseases, Rigshospitalet, Copenhagen 1982-1988.
Topics: Adolescent; Adult; Aged; Animals; Child; Child, Preschool; Denmark; Drug Therapy, Combination; Follow-Up Studies; Humans; Infant; Malaria; Mefloquine; Middle Aged; Plasmodium falciparum; Quinine | 1990 |
[Imported malaria in Bordeaux in 1989. Epidemiologic, clinical and therapeutic study of 71 cases].
Topics: Animals; Antimalarials; Chloroquine; Female; France; Humans; Malaria; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Travel | 1990 |
An in-vitro profile of the action of four antimalarials on indigenous cases of Plasmodium falciparum malaria in Karnataka.
Topics: Amodiaquine; Animals; Chloroquine; Drug Resistance, Microbial; Malaria; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine | 1990 |
[Clinical and therapeutic approach in Plasmodium falciparum malaria in non-immune patients].
Topics: Animals; Drug Resistance, Microbial; Humans; Malaria; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine | 1990 |
[A case of Plasmodium falciparum malaria contracted in Guinea-Bissau during chemoprophylaxis with chloroquine].
Topics: Animals; Chloroquine; Drug Resistance; Female; Humans; Malaria; Mefloquine; Middle Aged; Plasmodium falciparum; Quinine | 1990 |
Falciparum malaria resistant to quinine and pyrimethamine-sulfadoxine successfully treated with mefloquine.
Topics: Adult; Animals; Antimalarials; Child, Preschool; Drug Combinations; Drug Resistance; Female; Humans; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Sulfanilamides | 1990 |
[Plasmodium falciparum drug resistance in the Congo. Evaluation of surveys carried out from 1985 to 1989].
Topics: Adolescent; Aminoquinolines; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Congo; Drug Combinations; Drug Resistance; Humans; Infant; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1990 |
Potentiation of chloroquine activity against Plasmodium falciparum by the peroxidase-hydrogen peroxide system.
Topics: Animals; Cells, Cultured; Chloroquine; Drug Synergism; Hydrogen Peroxide; Hypoxanthine; Hypoxanthines; Mefloquine; Peroxidases; Plasmodium falciparum; Quinine | 1990 |
A nuclear magnetic resonance study of the interactions of the antimalarials chloroquine, quinacrine, quinine and mefloquine with lipids extracted from normal human erythrocytes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Antimalarials; Chloroquine; Deuterium; Erythrocytes; Humans; Magnetic Resonance Spectroscopy; Mefloquine; Membrane Lipids; Phosphatidylethanolamines; Phosphorus Isotopes; Quinacrine; Quinine | 1990 |
Effects of chloroquine, mefloquine and quinine on natural killer cell activity in vitro. An analysis of the inhibitory mechanism.
Topics: Cell Adhesion; Chloroquine; Cytotoxicity, Immunologic; Humans; Immunity, Cellular; Immunity, Innate; In Vitro Techniques; Interferons; Interleukin-2; Killer Cells, Natural; Mefloquine; Quinine; Quinolines | 1986 |
[Surveillance of Plasmodium falciparum drug sensitivity in Yaounde and its surroundings (Cameroon). In vivo and in vitro study].
Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Cameroon; Child; Child, Preschool; Chloroquine; Humans; In Vitro Techniques; Infant; Malaria; Mefloquine; Microbial Sensitivity Tests; Middle Aged; Plasmodium falciparum; Quinine; Quinolines; Rural Population | 1989 |
[Sensitivity of Plasmodium falciparum to different antimalarials. A study in 1988 in a village in the Hauts-Plateaux of Madagascar].
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Madagascar; Mefloquine; Plasmodium falciparum; Quinine | 1989 |
Ultrastructural comparison of erythrocytic stages of experimentally selected drug resistant strains of rodent malaria parasite P. berghei with its susceptible strain.
Topics: Animals; Drug Resistance; Erythrocytes; Mefloquine; Mice; Microscopy, Electron; Plasmodium berghei; Quinine | 1989 |
A nuclear magnetic resonance study of the interactions of the antimalarials chloroquine, quinacrine, quinine and mefloquine with dipalmitoylphosphatidylcholine bilayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Antimalarials; Chloroquine; Lipid Bilayers; Magnetic Resonance Spectroscopy; Mefloquine; Quinacrine; Quinine; Quinolines; Temperature | 1989 |
High rate of Plasmodium vivax relapse following treatment of falciparum malaria in Thailand.
Topics: Acute Disease; Adolescent; Adult; Animals; Antimalarials; Chloroquine; Female; Follow-Up Studies; Humans; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Quinidine; Quinine; Quinolines; Recurrence; Thailand | 1987 |
In vitro sensitivity of Plasmodium falciparum isolates from Burma to chloroquine quinine and mefloquine.
Topics: Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Mefloquine; Myanmar; Plasmodium falciparum; Quinine; Quinolines | 1985 |
[In vitro activity of various antimalarials (chloroquine, amodiaquine, quinine and mefloquine) against 32 isolates of Plasmodium falciparum in French Guiana].
Topics: Amodiaquine; Animals; Chloroquine; Drug Resistance; French Guiana; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1988 |
Response of Kampuchean strains of Plasmodium falciparum to antimalarials: in-vivo assessment of quinine and quinine plus tetracycline; multiple drug resistance in vitro.
Topics: Adolescent; Adult; Animals; Cambodia; Chloroquine; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Humans; In Vitro Techniques; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinine; Quinolines; Tetracycline | 1988 |
Patterns of in vitro resistance to chloroquine, quinine, and mefloquine of Plasmodium falciparum in Cameroon, 1985-1986.
Topics: Adolescent; Animals; Antimalarials; Cameroon; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Infant; Mefloquine; Plasmodium falciparum; Quinine; Quinolines; Time Factors | 1988 |
Serial studies on the evolution of drug resistance in malaria in an area of east Africa: findings from 1979 up to 1986.
Topics: Age Factors; Amodiaquine; Animals; Antibodies, Protozoan; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Infant; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinidine; Quinine; Quinolines; Sulfadoxine; Tanzania | 1988 |
Antagonism of chloroquine with other antimalarials.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Interactions; Drug Resistance; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine | 1988 |
Chloroquine-resistant Plasmodium falciparum in Mali revealed by congenital malaria.
Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Resistance; Female; Humans; Infant, Newborn; Malaria; Mali; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1988 |
Multiple drug resistant Plasmodium falciparum malaria in a pregnant indigenous Zambian woman.
Topics: Adult; Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Erythromycin; Female; Humans; Malaria; Mefloquine; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Infectious; Pyrimethamine; Quinine; Quinolines; Sulfadoxine | 1988 |
Action of mefloquine on agonist-induced contractions of the guinea-pig isolated ileum.
Topics: Acetylcholine; Animals; Dinoprostone; Female; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Mefloquine; Muscle Contraction; Muscle, Smooth; Quinine | 1988 |
Evaluation of an in vitro assay system for drug susceptibility of field isolates of Plasmodium falciparum from southern Thailand.
Topics: Amodiaquine; Animals; Antimalarials; Butylated Hydroxytoluene; Chloroquine; Humans; Mefloquine; Parasitology; Phenanthrenes; Plasmodium falciparum; Pyridines; Pyrimethamine; Quinine; Quinolines; Thailand; Triazines | 1988 |
In vitro activity of pyronaridine against field isolates and reference clones of Plasmodium falciparum.
Topics: Amodiaquine; Animals; Antimalarials; Chemical Phenomena; Chemistry; Chloroquine; Drug Resistance; Humans; Mefloquine; Naphthyridines; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Thailand | 1988 |
Effects of quinoline-containing antimalarials on the erythrocyte membrane and their significance to drug action on Plasmodium falciparum.
Topics: Animals; Antimalarials; Chloroquine; Erythrocyte Membrane; Hemolysis; Humans; Hydrogen-Ion Concentration; Mefloquine; Phospholipids; Plasmodium falciparum; Potassium; Proteins; Quinine; Quinolines | 1988 |
In vitro susceptibility of Plasmodium falciparum to amodiaquine, mefloquine, quinine and chloroquine in Liberia, West Africa.
Topics: Amodiaquine; Animals; Chloroquine; Drug Resistance; Liberia; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1986 |
In vitro drug response of Plasmodium falciparum in the Philippines: increased resistance to amodiaquine.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Philippines; Plasmodium falciparum; Quinine; Quinolines | 1987 |
Flunarizine and verapamil inhibit chloroquine-resistant Plasmodium falciparum growth in vitro.
Topics: Animals; Antimalarials; Chloroquine; Chlorpromazine; Drug Resistance; Flunarizine; Mefloquine; Plasmodium falciparum; Quinine; Quinolines; Regression Analysis; Verapamil | 1987 |
[Sensitivity of Plasmodium falciparum to quinolines and therapeutic strategies: comparison of the situation in Africa and Madagascar between 1983 and 1986].
Topics: Amodiaquine; Angola; Animals; Antimalarials; Burkina Faso; Cameroon; Chloroquine; Drug Resistance; Humans; Madagascar; Malaria; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1987 |
[Value of exchange transfusion in the treatment of severe malaria (apropos of 5 cases)].
Topics: Adult; Animals; Antimalarials; Combined Modality Therapy; Exchange Transfusion, Whole Blood; Female; Humans; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinine; Quinolines | 1987 |
Effect of antimalarial drugs on stimulation and interleukin 2 production of human lymphocytes.
Topics: Antimalarials; Candida; Cells, Cultured; Chloroquine; Drug Administration Schedule; Humans; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Mefloquine; Protein Biosynthesis; Pyrimethamine; Quinine; Quinolines; Tuberculin | 1987 |
High level of sensitivity to chloroquine of 72 Plasmodium falciparum isolates from southern Cameroon in January 1985.
Topics: Animals; Antimalarials; Cameroon; Child; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1986 |
Digestion of the host erythrocyte by malaria parasites is the primary target for quinoline-containing antimalarials.
Topics: Amino Acids; Ammonium Chloride; Animals; Antimalarials; Chloroquine; Erythrocytes; Host-Parasite Interactions; Humans; Mefloquine; Methylamines; Plasmodium falciparum; Quinine; Quinolines; Vacuoles | 1986 |
[Preliminary study, in vitro, of the sensitivity of P. falciparum to chloroquine, mefloquine and quinine during 1985, in Kampuchea].
Topics: Adult; Antimalarials; Cambodia; Chloroquine; Humans; Malaria; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Quinolines | 1986 |
In vitro effect of chloroquine, mefloquine and quinine on human lymphocyte proliferative responses to malaria antigens and other antigens/mitogens.
Topics: Adult; Antigens, Fungal; Antigens, Protozoan; Candida albicans; Chloroquine; Humans; Lymphocyte Activation; Mefloquine; Mitogens; Plasmodium falciparum; Quinine; Quinolines; Tuberculin | 1986 |
Effects of combinations of quinoline-containing antimalarials on Plasmodium falciparum in culture.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Interactions; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1986 |
Sensitivity to quinine and mefloquine of Plasmodium falciparum in Thailand.
Topics: Antimalarials; Drug Resistance; Mefloquine; Plasmodium falciparum; Quinine; Quinolines; Thailand | 1986 |
Chloroquine-resistant falciparum malaria from East Africa.
Topics: Adult; Africa, Eastern; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sulfadoxine | 1986 |
Plasmodium falciparum drug resistance in West Africa.
Topics: Africa, Western; Animals; Antimalarials; Chloroquine; Drug Resistance; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1986 |
[Development of P. falciparum sensitivity to chloroquine, to quinine and to mefloquine between 1983 and 1985 in Zaire].
Topics: Animals; Antimalarials; Chloroquine; Democratic Republic of the Congo; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1986 |
Preliminary observations on development of quinine sulphate resistance in Plasmodium berghei.
Topics: Animals; Antimalarials; Drug Resistance; Mefloquine; Mice; Plasmodium berghei; Quinine; Quinolines | 1986 |
Antimalarial drug susceptibility testing of Plasmodium falciparum in Thailand using a microdilution radioisotope method.
Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Lethal Dose 50; Malaria; Male; Mefloquine; Microbial Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine; Quinolines; Thailand | 1985 |
Studies of resistance to chloroquine, quinine, amodiaquine and mefloquine among Philippine strains of Plasmodium falciparum.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Mefloquine; Philippines; Plasmodium falciparum; Quinine; Quinolines | 1985 |
Mefloquine failure in a case of falciparum malaria induced with a multidrug-resistant isolate in a non-immune subject.
Topics: Adult; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Pyridines; Quinine; Quinolines | 1985 |
Antimalarials increase vesicle pH in Plasmodium falciparum.
Topics: Ammonia; Animals; Antimalarials; Biological Transport; Chloroquine; Erythrocytes; Hydrogen-Ion Concentration; Lysosomes; Mefloquine; Organoids; Plasmodium falciparum; Quinine; Quinolines | 1985 |
[Sensitivity of strains of Plasmodium falciparum to chloroquine, mefloquine and quinine in 1983 in Zaire].
Topics: Animals; Antimalarials; Chloroquine; Democratic Republic of the Congo; Drug Resistance, Microbial; In Vitro Techniques; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1985 |
Plasmodium falciparum in Madagascar: in vivo and in vitro sensitivity to seven drugs.
Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Humans; Infant; Madagascar; Malaria; Mefloquine; Microbial Sensitivity Tests; Middle Aged; Phenanthrenes; Piperazines; Plasmodium falciparum; Quinine; Quinolines | 1985 |
[Malaria chemoprophylaxis. Resistance problems].
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Microbial; Humans; Infant; Malaria; Mefloquine; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Quinolines; Sulfadoxine | 1985 |
Interactions of hemin, antimalarial drugs and hemin-antimalarial complexes with phospholipid monolayers.
Topics: Animals; Antimalarials; Cattle; Chloroquine; Heme; Hemin; Mathematics; Mefloquine; Membranes, Artificial; Phospholipids; Quinine; Quinolines; Surface Properties | 1984 |
The effect of anti-malarial drugs on human natural killer cells in vitro.
Topics: Antimalarials; Cell Line; Chloroquine; Cytotoxicity, Immunologic; Humans; Killer Cells, Natural; Leukemia, Myeloid, Acute; Mefloquine; Primaquine; Pyrimethamine; Quinacrine; Quinine; Quinolines | 1984 |
In vitro study of drug sensitivity of Plasmodium falciparum: evaluation of a new semi-micro test.
Topics: Antimalarials; Chloroquine; Evaluation Studies as Topic; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Quinolines | 1983 |
Susceptibility of Plasmodium falciparum to five drugs: an in vitro study of isolates mainly from Thailand.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; In Vitro Techniques; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Thailand | 1983 |
Plasmodium falciparum: drug sensitivity in vitro of isolates before and after adaptation to continuous culture.
Topics: Adaptation, Physiological; Animals; Antimalarials; Chloroquine; Drug Resistance; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1983 |
The treatment of falciparum malaria.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium falciparum; Quinidine; Quinine; Quinolines; Sesquiterpenes | 1984 |
The relationship between the in vitro response of Plasmodium falciparum to chloroquine, quinine and mefloquine.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1984 |
Application of an in vitro semi-microtest to the study of drug sensitivity of 66 Plasmodium falciparum isolates from 15 countries.
Topics: Animals; Chloroquine; Drug Resistance, Microbial; Mefloquine; Microbial Sensitivity Tests; Piperazines; Plasmodium falciparum; Quinine; Quinolines | 1984 |
[In vitro sensitivity tests of Plasmodium falciparum samples of the Amazonian Basin (Brazil)].
Topics: Amodiaquine; Animals; Antimalarials; Brazil; Chloroquine; In Vitro Techniques; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines | 1983 |
[Drug sensitivity of Plasmodium falciparum in Madagascar. V. Study of the in vitro activity of quinine, mefloquine and halofantrine].
Topics: Antimalarials; Chloroquine; Humans; Mefloquine; Microbial Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine; Quinolines | 1984 |
Diverse membrane-active agents modify the hemolytic response to ferriprotoporphyrin IX.
Topics: Adult; Antimalarials; Calcium; Chloroquine; Drug Synergism; Erythrocytes; Female; Heme; Hemin; Hemolysis; Humans; Male; Mefloquine; Osmotic Fragility; Quinine; Quinolines; Sodium Chloride | 1983 |
[Standardisation of the in vitro chemosensitivity test for Plasmodium falciparum ].
Topics: Antimalarials; Chloroquine; Drug Resistance, Microbial; Erythrocytes; Humans; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Quinolines | 1982 |
[How to treat malaria in the 80s (author's transl)].
Topics: China; Drug Resistance, Microbial; Humans; Malaria; Mefloquine; Piperidines; Plant Extracts; Plants, Medicinal; Quinine; Quinolines; World Health Organization | 1981 |
In vitro susceptibility of Plasmodium falciparum to chloroquine, amodiaquine, quinine, mefloquine, and sulfadoxine/pyrimethamine in Equatorial Guinea.
Topics: Amodiaquine; Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Equatorial Guinea; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Regression Analysis; Sulfadoxine | 1995 |
Quinine resistant falciparum malaria acquired in east Africa.
Topics: Adult; Africa, Eastern; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Tetracycline | 1995 |
Prevention of malaria in travellers from the United Kingdom.
Topics: Adult; Antimalarials; Developing Countries; Drug Combinations; Female; Humans; Malaria; Male; Mefloquine; Pyrimethamine; Quinine; Sulfadoxine; Travel; United Kingdom | 1993 |
Stage sensitivity of Plasmodium vinckei petteri to quinine, mefloquine, and pyrimethamine.
Topics: Animals; Malaria; Male; Mefloquine; Mice; Plasmodium; Pyrimethamine; Quinine; Time Factors | 1995 |
Drug-resistant Plasmodium falciparum malaria in the eastern Transvaal.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1994 |
Plasmodium falciparum and Plasmodium vivax: lactate dehydrogenase activity and its application for in vitro drug susceptibility assay.
Topics: Animals; Antimalarials; Chloroquine; Colorimetry; Erythrocytes; Humans; L-Lactate Dehydrogenase; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Phenanthrenes; Plasmodium falciparum; Plasmodium vivax; Quinine | 1995 |
[In vitro sensitivity of Plasmodium falciparum to mefloquine, quinine, amodiaquine, chloroquine, pyronaridine and sulfadoxine/pyrimethamine in south Yunnan].
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Mefloquine; Naphthyridines; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1994 |
A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro.
Topics: Animals; Antimalarials; Artemisinins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Northern; Blotting, Southern; Chloroquine; DNA Primers; DNA, Protozoan; Drug Resistance; Gene Amplification; Gene Expression; Genes, Protozoan; Mefloquine; Molecular Sequence Data; Phenanthrenes; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Quinine; RNA, Messenger; Selection, Genetic; Sequence Homology, Nucleic Acid; Sesquiterpenes | 1994 |
Ten-year surveillance of drug-resistant malaria in Burkina Faso (1982-1991).
Topics: Adolescent; Animals; Antimalarials; Burkina Faso; Child; Chloroquine; Drug Resistance; Humans; Longitudinal Studies; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Prevalence; Pyrimethamine; Quinine; Retrospective Studies; Sulfadoxine | 1994 |
In vitro susceptibility of Cambodian isolates of Plasmodium falciparum to halofantrine, pyronaridine and artemisinin derivatives.
Topics: Adult; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; In Vitro Techniques; Mefloquine; Naphthyridines; Phenanthrenes; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Triazines | 1994 |
In vitro effects of artemisinin ether, cycloguanil hydrochloride (alone and in combination with sulfadiazine), quinine sulfate, mefloquine, primaquine phosphate, trifluoperazine hydrochloride, and verapamil on Toxoplasma gondii.
Topics: Animals; Artemisinins; Female; Mefloquine; Mice; Primaquine; Proguanil; Quinine; Sesquiterpenes; Sulfadiazine; Toxoplasma; Triazines; Trifluoperazine; Uracil; Verapamil | 1994 |
In vitro activity of pyrimethamine, cycloguanil, and other antimalarial drugs against African isolates and clones of Plasmodium falciparum.
Topics: Africa; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Mefloquine; Phenanthrenes; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Triazines | 1994 |
Efficacy of chloroquine on Plasmodium falciparum transmitted at Amani, eastern Usambara Mountains, north-east Tanzania: an area where malaria has recently become endemic.
Topics: Adolescent; Adult; Amodiaquine; Animals; Child; Child, Preschool; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Female; Follow-Up Studies; Hemoglobins; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinine; Regression Analysis; Sickle Cell Trait; Tanzania | 1993 |
Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine.
Topics: Animals; Chromosome Mapping; Drug Resistance; Gene Amplification; Gene Expression; Genes, Protozoan; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine | 1994 |
Isolated pontine lesion in algid cerebral malaria: clinical features, management, and magnetic resonance imaging findings.
Topics: Adult; Blood Component Transfusion; Exchange Transfusion, Whole Blood; Female; Humans; Magnetic Resonance Imaging; Malaria, Cerebral; Mefloquine; Plasma; Pons; Quinine | 1993 |
In vitro activity of artemisinin derivatives against African isolates and clones of Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Resistance; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes | 1993 |
Pharmacological activity and structure-activity relationship of (+/-)-erythro-mefloquine and related compounds on the isolated mouse phrenic nerve diaphragm preparation.
Topics: Animals; Antimalarials; Bungarotoxins; Electric Stimulation; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Mefloquine; Mice; Models, Molecular; Molecular Conformation; Muscle Contraction; Neuromuscular Junction; Phenanthrenes; Phrenic Nerve; Quinine; Quinolines; Structure-Activity Relationship | 1993 |
Interactions among primaquine, malaria infection and other antimalarials in Thai subjects.
Topics: Acute Disease; Administration, Oral; Adult; Drug Interactions; Humans; Malaria, Falciparum; Male; Mefloquine; Primaquine; Quinine; Thailand | 1993 |
Derivation of highly mefloquine-resistant lines from Plasmodium falciparum in vitro.
Topics: Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Erythrocytes; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Serial Passage; Vacuoles | 1993 |
Abnormal circulatory control in falciparum malaria: the effects of antimalarial drugs.
Topics: Acute Disease; Adolescent; Adult; Aged; Analysis of Variance; Antimalarials; Blood Pressure; Convalescence; Female; Heart Rate; Humans; Hypotension, Orthostatic; Linear Models; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Prospective Studies; Quinine | 1993 |
Malaria among United States troops in Somalia.
Topics: Anti-Bacterial Agents; Antimalarials; Chemoprevention; Chloroquine; Clothing; Cohort Studies; Doxycycline; Drug Resistance; Humans; Malaria, Cerebral; Malaria, Falciparum; Male; Mefloquine; Military Personnel; Population Surveillance; Prospective Studies; Protective Devices; Pyrimethamine; Quinine; Risk Factors; Somalia; Sulfadoxine; Treatment Failure; Treatment Refusal; United States | 1996 |
Effect of pH on in vitro potency of amantadine against Plasmodium falciparum.
Topics: Adamantane; Amantadine; Ammonium Chloride; Animals; Antimalarials; Chloroquine; Culture Media; Dose-Response Relationship, Drug; Drug Resistance; Humans; Hydrogen-Ion Concentration; Mefloquine; Plasmodium falciparum; Quinine | 1996 |
The pfmdr1 gene of Plasmodium falciparum confers cellular resistance to antimalarial drugs in yeast cells.
Topics: Alleles; Animals; Antimalarials; ATP-Binding Cassette Transporters; Dose-Response Relationship, Drug; Drug Resistance; Mefloquine; Mice; Phenanthrenes; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinacrine; Quinine | 1996 |
In vitro drug sensitivity and clinical aspects of Plasmodium falciparum malaria in African children.
Topics: Animals; Child; Child, Preschool; Chloroquine; Congo; Humans; Infant; Malaria, Falciparum; Mefloquine; Parasitemia; Plasmodium falciparum; Quinine | 1995 |
The effect of mefloquine and quinine on the relaxation times of water protons in human erythrocytes, as revealed by NMR.
Topics: Adult; Antimalarials; Body Water; Cell Membrane Permeability; Erythrocyte Membrane; Erythrocytes; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Mefloquine; Protons; Quinine | 1996 |
Hemophagocytic syndrome induced by Plasmodium falciparum malaria infection.
Topics: Adult; Antimalarials; Biomarkers; Cytokines; Histiocytosis, Non-Langerhans-Cell; Humans; Malaria, Falciparum; Male; Mefloquine; Quinine | 1996 |
In vitro selection of halofantrine resistance in Plasmodium falciparum is not associated with increased expression of Pgh1.
Topics: Animals; Antimalarials; ATP-Binding Cassette Transporters; Biological Transport; Chloroquine; DNA Fingerprinting; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Multiple; Gene Dosage; Gene Expression; Immunoblotting; Mefloquine; Phenanthrenes; Plasmodium falciparum; Protozoan Proteins; Quinine; Selection, Genetic; Sequence Analysis, DNA; Verapamil | 1996 |
High prevalence of chloroquine resistant Plasmodium falciparum infection in Rajasthan epidemic.
Topics: Animals; Antibodies, Protozoan; Antimalarials; Chloroquine; Disease Outbreaks; Drug Resistance, Microbial; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin G; Immunoglobulin M; India; Malaria, Falciparum; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinine; Seroepidemiologic Studies; Sulfadoxine; Tumor Necrosis Factor-alpha | 1996 |
In vitro susceptibility of Plasmodium falciparum isolates in Vietnam to artemisinin derivatives and other antimalarials.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes; Vietnam | 1997 |
Activity of pyronaridine and mepacrine against twelve strains of Plasmodium falciparum in vitro.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Mefloquine; Naphthyridines; Plasmodium falciparum; Quinacrine; Quinine | 1996 |
Recrudescence of Plasmodium falciparum malaria contracted in Lombok, Indonesia after quinine/doxycycline and mefloquine: case report.
Topics: Adult; Animals; Anti-Bacterial Agents; Antimalarials; Doxycycline; Drug Combinations; Drug Resistance, Multiple; Humans; Indonesia; Malaria, Cerebral; Malaria, Falciparum; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Recurrence | 1997 |
[29 cases of malaria introduced into New Caledonia from 1992 to 1995].
Topics: Adolescent; Adult; Antimalarials; Female; France; Hospitalization; Humans; Incidence; Length of Stay; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; New Caledonia; Quinine; Retrospective Studies; Travel | 1997 |
Thermodynamics of partitioning of the antimalarial drug mefloquine in phospholipid bilayers and bulk solvents.
Topics: 1-Octanol; Antimalarials; Dimyristoylphosphatidylcholine; Gels; Hexanes; Hydrogen Bonding; Lipid Bilayers; Liposomes; Mefloquine; Quinine; Solvents; Temperature; Thermodynamics | 1997 |
In vitro blood schizonticidal activity of sera containing mefloquine-quinine against Plasmodium falciparum.
Topics: Animals; Antimalarials; Drug Therapy, Combination; Erythrocytes; Humans; In Vitro Techniques; Malaria, Falciparum; Male; Mefloquine; Parasitemia; Plasmodium falciparum; Quinine | 1997 |
Pfmdr1 Asn1042Asp and Asp1246Tyr polymorphisms, thought to be associated with chloroquine resistance, are present in chloroquine-resistant and -sensitive Brazilian field isolates of Plasmodium falciparum.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Mefloquine; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Quinine | 1998 |
In vitro activity of artemether against African isolates (Senegal) of Plasmodium falciparum in comparison with standard antimalarial drugs.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Erythrocytes; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Senegal; Sesquiterpenes | 1998 |
A primary malarial infection is composed of a very wide range of genetically diverse but related parasites.
Topics: Africa; Animals; Antimalarials; Biomarkers; Chloroquine; Clone Cells; Culicidae; Drug Resistance; Genetic Variation; Humans; Insect Bites and Stings; Malaria, Falciparum; Mefloquine; Parasitology; Phenotype; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Quinine; Thailand | 1998 |
Follow-up of the susceptibility of Plasmodium falciparum to antimalarials in Gabon.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Follow-Up Studies; Gabon; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes; Sulfadoxine | 1998 |
Characterization of Plasmodium falciparum isolated from the Amazon region of Brazil: evidence for quinine resistance.
Topics: Animals; Antimalarials; ATP-Binding Cassette Transporters; Brazil; DNA, Protozoan; Drug Resistance; Drug Resistance, Multiple; Drug Therapy, Combination; Genes, Protozoan; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Quinine | 1998 |
In vitro sensitivity of Plasmodium falciparum to halofantrine compared with chloroquine, quinine and mefloquine in the region of Bobo-Dioulasso, Burkina Faso (West Africa).
Topics: Animals; Antimalarials; Burkina Faso; Chloroquine; Drug Resistance; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine | 1998 |
Recurrence of blackwater fever: triggering of relapses by different antimalarials.
Topics: Adult; Aged; Antimalarials; Belgium; Blackwater Fever; Diagnosis, Differential; Female; Humans; Male; Mefloquine; Middle Aged; Phenanthrenes; Quinine; Recurrence | 1998 |
In vitro susceptibility studies of Malaysian Plasmodium falciparum isolates and clones against schizontocidal drugs.
Topics: Animals; Antimalarials; Chloroquine; Malaysia; Mefloquine; Plasmodium falciparum; Quinine | 1998 |
Monoclonal antibodies to quinine.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Antimalarials; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hybridomas; Immunoglobulin G; Mefloquine; Mice; Mice, Inbred BALB C; Quinine; Serum Albumin, Bovine | 1998 |
Quinine and mefloquine in the treatment of multidrug-resistant Plasmodium falciparum malaria in pregnancy.
Topics: Adolescent; Adult; Animals; Antimalarials; Drug Resistance, Multiple; Female; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Quinine; Thailand; Treatment Outcome | 1998 |
[The proper use of antimalarial drugs currently available].
Topics: Animals; Antimalarials; Chemoprevention; Chloroquine; Contraindications; Drug Combinations; Drug Resistance; Endemic Diseases; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Phenanthrenes; Plasmodium; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Proguanil; Pyrimethamine; Quinine; Sulfadoxine; Travel | 1998 |
[Pulmonary manifestations associated with malaria].
Topics: Adult; Anti-Bacterial Agents; Antimalarials; Bronchitis; Child; Chloroquine; Female; Humans; Infant, Newborn; Lung Diseases; Malaria, Falciparum; Male; Mefloquine; Oxygen Inhalation Therapy; Phenanthrenes; Pleurisy; Pregnancy; Pregnancy Complications, Parasitic; Pulmonary Edema; Quinidine; Quinine; Respiratory Distress Syndrome, Newborn; Travel | 1998 |
Risk factors for gametocyte carriage in uncomplicated falciparum malaria.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Carrier State; Child; Child, Preschool; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Multivariate Analysis; Parasitemia; Phenanthrenes; Plasmodium falciparum; Prospective Studies; Quinine; Regression Analysis; Risk Factors; Seroepidemiologic Studies; Sesquiterpenes; Thailand | 1999 |
Plasmodium chabaudi: effect of antimalarial drugs on gametocytogenesis.
Topics: Animals; Antimalarials; Chloroquine; Gametogenesis; Malaria; Male; Mefloquine; Mice; Mice, Inbred C57BL; Plasmodium chabaudi; Pyrimethamine; Quinine | 1999 |
Phenotypic and genotypic characteristics of recently adapted isolates of Plasmodium falciparum from Thailand.
Topics: Animals; Antimalarials; Blotting, Western; Chloroquine; DNA Fingerprinting; DNA, Protozoan; Drug Resistance; Electrophoresis, Agar Gel; Gene Dosage; Genotype; Humans; Malaria, Falciparum; Mefloquine; Penfluridol; Phenanthrenes; Phenotype; Plasmodium falciparum; Polymerase Chain Reaction; Quinine; Thailand; Verapamil | 1999 |
The microculture tetrazolium assay (MTA): another colorimetric method of testing Plasmodium falciparum chemosensitivity.
Topics: Animals; Antimalarials; Chloroquine; Colorimetry; Dose-Response Relationship, Drug; Drug Resistance; L-Lactate Dehydrogenase; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Tetrazolium Salts | 1999 |
Analysis of mefloquine resistance and amplification of pfmdr1 in multidrug-resistant Plasmodium falciparum isolates from Thailand.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Chromosome Mapping; DNA Primers; DNA, Protozoan; Drug Resistance, Multiple; Electrophoresis, Agar Gel; Electrophoresis, Gel, Pulsed-Field; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Quinine; Scintillation Counting; Sequence Analysis, DNA; Thailand | 1999 |
Inoculum effect leads to overestimation of in vitro resistance for artemisinin derivatives and standard antimalarials: a Gambian field study.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Gambia; Hematocrit; Humans; Malaria, Falciparum; Mefloquine; Parasitemia; Phenanthrenes; Plasmodium falciparum; Quinine; Scintillation Counting; Sensitivity and Specificity; Sesquiterpenes | 1999 |
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum.
Topics: Amino Acid Substitution; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Cloning, Molecular; Drug Resistance; Mefloquine; Mutation; Phenanthrenes; Plasmodium falciparum; Protozoan Proteins; Quinine; Sesquiterpenes; Verapamil | 2000 |
The Thai-Burmese border: drug studies of Plasmodium falciparum in pregnancy.
Topics: Antimalarials; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Mefloquine; Myanmar; Pregnancy; Pregnancy Complications, Parasitic; Quinine; Sesquiterpenes; Thailand | 1999 |
Prevention and treatment of malaria in UK travellers.
Topics: Age Factors; Antimalarials; Chloroquine; Contraindications; Doxycycline; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Proguanil; Quinine; Risk Factors; Travel | 2000 |
In vitro susceptibility of Plasmodium falciparum to four antimalarial drugs in the Central Province of Papua New Guinea.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Mefloquine; Microbial Sensitivity Tests; Papua New Guinea; Phenanthrenes; Plasmodium falciparum; Quinine | 1998 |
Interaction of chloroquine and its analogues with heme: An isothermal titration calorimetric study.
Topics: Amodiaquine; Antimalarials; Binding Sites; Calorimetry; Chloroquine; Hemin; Hydrogen-Ion Concentration; Mefloquine; Octoxynol; Quinidine; Quinine; Solubility; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics; Titrimetry | 2000 |
The antimalarial agent mefloquine inhibits ATP-sensitive K-channels.
Topics: Adenosine Triphosphate; Animals; Antimalarials; Female; Insulin; Insulin Secretion; Mefloquine; Mice; Potassium Channels; Quinine; Rats; Xenopus laevis | 2000 |
Declining chloroquine resistance of Plasmodium falciparum in Lambaréné, Gabon from 1992 to 1998.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Gabon; Humans; In Vitro Techniques; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Practice Guidelines as Topic; Prospective Studies; Quinine | 2001 |
Use of the DELI-microtest to determine the drug sensitivity of Plasmodium falciparum in Burkina Faso.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Malaria, Falciparum; Mefloquine; Parasitemia; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Reagent Kits, Diagnostic; Sensitivity and Specificity; Statistics, Nonparametric | 2001 |
Development of stereoselective nonaqueous capillary electrophoresis system for the resolution of cationic and amphoteric analytes.
Topics: Carbamates; Cations; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Indicators and Reagents; Leucine; Mefloquine; Molecular Structure; Nitrobenzoates; Quinidine; Quinine; Stereoisomerism | 2001 |
In vitro interactions of artemisinin with atovaquone, quinine, and mefloquine against Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemisinins; Atovaquone; Drug Synergism; Humans; Mefloquine; Naphthoquinones; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes | 2002 |
Crystal structure of (-)-mefloquine hydrochloride reveals consistency of configuration with biological activity.
Topics: Animals; Antimalarials; Crystallization; Crystallography, X-Ray; Hydrogen Bonding; Mefloquine; Molecular Conformation; Plasmodium falciparum; Quinidine; Quinine; Stereoisomerism | 2002 |
Resistant malaria in a neonate.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant, Newborn; Malaria, Falciparum; Mefloquine; Quinine; Risk Assessment; Sesquiterpenes; Severity of Illness Index; Treatment Outcome | 2002 |
[Blackwater fever].
Topics: Adolescent; Adult; Aged; Antimalarials; Atovaquone; Blackwater Fever; Critical Care; Diagnosis, Differential; Drug Combinations; Humans; Mefloquine; Middle Aged; Naphthoquinones; Phenanthrenes; Prognosis; Proguanil; Pyrimethamine; Quinine; Sulfadoxine | 2002 |
Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations.
Topics: Alleles; Amodiaquine; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Cloning, Molecular; Drug Resistance; Genes, Protozoan; Haplotypes; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Parasitic Sensitivity Tests; Phenotype; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Quinine; Sesquiterpenes; Transfection; Verapamil | 2002 |
Atovaquone + proguanil: new preparation. Second-line antimalarial combination.
Topics: Antimalarials; Clinical Trials as Topic; Developing Countries; Drug Approval; Drug Combinations; Drug Costs; Drug Interactions; Drug Resistance; Ethics, Medical; France; Humans; Malaria, Falciparum; Mefloquine; Naphthoquinones; Phenanthrenes; Proguanil; Quinine; Randomized Controlled Trials as Topic; Travel | 2002 |
Haem polymerase as a novel target of antimalarial action of cyproheptadine.
Topics: Animals; Antimalarials; Chloroquine; Cyproheptadine; Disease Models, Animal; Drug Resistance; Enzyme Inhibitors; Hemeproteins; Mefloquine; Mice; Plasmodium yoelii; Quinine; Transferases; Treatment Outcome | 2002 |
The clinical spectrum of severe imported falciparum malaria in the intensive care unit: report of 188 cases in adults.
Topics: Adolescent; Adult; Aged; Antimalarials; Community-Acquired Infections; Comorbidity; Cross Infection; Data Interpretation, Statistical; Exchange Transfusion, Whole Blood; Female; France; Glasgow Coma Scale; Humans; Injections, Intravenous; Intensive Care Units; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Phenanthrenes; Quinine; Retrospective Studies; Travel; World Health Organization | 2003 |
Molecular characterisation of drug-resistant Plasmodium falciparum from Thailand.
Topics: Amodiaquine; Animals; Antimalarials; ATP-Binding Cassette Transporters; Chloroquine; Drug Resistance; Drug Resistance, Multiple; Gene Frequency; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Thailand | 2002 |
In vitro activity of chloroquine, quinine, mefloquine and halofantrine against Gabonese isolates of Plasmodium falciparum.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Gabon; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine | 2003 |
[Assay of sensitivity of Plasmodium falciparum to chloroquine, amodiaquine, piperaquine, mefloquine and quinine in Yunnan province].
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1999 |
[Effect of pyronaridine, mefloquine and quinine on artesunate-sensitive and artesunate-resistant Plasmodium falciparum].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance; Drug Synergism; Mefloquine; Naphthyridines; Plasmodium falciparum; Quinine; Sesquiterpenes | 2000 |
Treatment of imported uncomplicated malaria: a medical emergency.
Topics: Antimalarials; Drug Resistance, Microbial; Emergencies; Emergency Medical Services; France; Humans; Malaria, Falciparum; Mefloquine; Quinine | 2003 |
Profile and evolution of the chemosusceptibility of falciparum malaria imported into France in 2000.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; France; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Proguanil; Quinine; Triazines | 2002 |
In-vitro sensitivity of Plasmodium falciparum to chloroquine, halofantrine, mefloquine and quinine in Madagascar.
Topics: Animals; Antimalarials; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Hospitals, Public; Hospitals, Urban; Humans; Madagascar; Malaria, Falciparum; Mefloquine; Microbial Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine; Rural Health | 2002 |
Drug-resistant malaria in Bangladesh: an in vitro assessment.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Bangladesh; Chloroquine; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes | 2003 |
In vitro sensitivity of Plasmodium falciparum to amodiaquine compared with other major antimalarials in Madagascar.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance; Drug Resistance, Multiple; Humans; Inhibitory Concentration 50; Madagascar; Malaria, Falciparum; Mefloquine; Parasitemia; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Triazines | 2002 |
[Malaria--case report].
Topics: Adult; Anti-Infective Agents; Antidiarrheals; Antimalarials; Chloroquine; Ciprofloxacin; Diarrhea; Emergencies; Fluid Therapy; Glasgow Coma Scale; Humans; Loperamide; Malaria, Cerebral; Malaria, Falciparum; Male; Mefloquine; Nigeria; Parasitemia; Positive-Pressure Respiration; Proguanil; Quinine; Respiratory Distress Syndrome; Travel | 2003 |
Mapping of the Plasmodium falciparum multidrug resistance gene 5'-upstream region, and evidence of induction of transcript levels by antimalarial drugs in chloroquine sensitive parasites.
Topics: 5' Untranslated Regions; Animals; Antimalarials; ATP-Binding Cassette Transporters; Base Sequence; Chloroquine; Chromosome Mapping; Drug Resistance, Multiple; Gene Expression Regulation; Genes, MDR; Genes, Protozoan; Genes, Reporter; Luciferases; Mefloquine; Molecular Sequence Data; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins; Pyrimethamine; Quinine; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Homology, Nucleic Acid; Transcription, Genetic | 2003 |
Reversal of mefloquine and quinine resistance in Plasmodium falciparum with NP30.
Topics: Animals; Antimalarials; Calcium Channel Blockers; Drug Resistance; Genotype; Humans; Malaria, Falciparum; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Surface-Active Agents; Verapamil | 2003 |
Susceptibility of Plasmodium falciparum to the drugs used to treat severe malaria (quinine) and to prevent malaria (mefloquine, cycloguanil) in Comoros Union and Madagascar.
Topics: Animals; Antimalarials; Comoros; Drug Resistance; Humans; In Vitro Techniques; Madagascar; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Proguanil; Quinine; Triazines | 2004 |
Malaria during pregnancy in a reference centre from the Brazilian Amazon: unexpected increase in the frequency of Plasmodium falciparum infections.
Topics: Adolescent; Adult; Antimalarials; Brazil; Child; Chloroquine; Cross-Sectional Studies; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Prevalence; Quinine | 2004 |
Defective DNA repair as a potential mechanism for the rapid development of drug resistance in Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; DNA Damage; DNA Repair; Drug Resistance; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine; Sesquiterpenes; Sulfanilamide; Sulfanilamides; Ultraviolet Rays | 2004 |
Photophysical and photobiological behavior of antimalarial drugs in aqueous solutions.
Topics: 3T3 Cells; Animals; Antimalarials; Cell Survival; DNA Damage; Free Radicals; Histidine; Lasers; Mefloquine; Membrane Lipids; Membrane Proteins; Mice; Photobiology; Photochemistry; Photolysis; Quinacrine; Quinine; Spectrometry, Fluorescence; Tryptophan; Ultraviolet Rays | 2004 |
Polymorphism of the Plasmodium falciparum multidrug resistance and chloroquine resistance transporter genes and in vitro susceptibility to aminoquinolines in isolates from the Peruvian Amazon.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Multiple; Genes, MDR; Genotype; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine | 2004 |
Application of multi-component reactions to antimalarial drug discovery. Part 1: Parallel synthesis and antiplasmodial activity of new 4-aminoquinoline Ugi adducts.
Topics: Animals; Antimalarials; Chloroquine; Mefloquine; Molecular Conformation; Molecular Structure; Plasmodium falciparum; Quinine; Structure-Activity Relationship | 2004 |
The sensitivities of yeast strains deficient in PDR ABC transporters, to quinoline-ring antimalarial drugs.
Topics: Antimalarials; ATP-Binding Cassette Transporters; Chloroquine; Cycloheximide; Drug Resistance, Multiple, Fungal; Gene Deletion; Genes, Fungal; Mefloquine; Mutation; Quinacrine; Quinidine; Quinine; Saccharomyces cerevisiae; Transcription, Genetic | 2004 |
In vitro monitoring of Plasmodium falciparum susceptibility to artesunate, mefloquine, quinine and chloroquine in Cambodia: 2001-2002.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cambodia; Chloroquine; Drug Resistance; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine; Sesquiterpenes; Statistics, Nonparametric | 2005 |
ATPase activity of purified plasma membranes and digestive vacuoles from Plasmodium falciparum.
Topics: Adenosine Triphosphatases; Animals; Antimalarials; Artemisinins; Cell Membrane; Chloroquine; Drug Resistance; Mefloquine; Plasmodium falciparum; Quinine; Sesquiterpenes; Subcellular Fractions; Vacuoles | 2005 |
In vitro antimalarial drug susceptibility in Thai border areas from 1998-2003.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine; Sesquiterpenes; Thailand; Time Factors | 2005 |
pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum.
Topics: Alleles; Animals; Antimalarials; Artemisinins; Asparagine; Aspartic Acid; ATP-Binding Cassette Transporters; Drug Resistance; Mefloquine; Phenanthrenes; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Quinine; Sesquiterpenes | 2005 |
[Atypical course of falciparum malaria in an asplenic patient].
Topics: Adult; Antimalarials; Humans; Malaria, Falciparum; Male; Mefloquine; Quinine; Recurrence; Splenectomy; Travel; Treatment Outcome | 2006 |
In vitro study assessing the response of plasmodium falciparum malaria to chloroquine, sulfadoxine/pyrimethamine, quinine and mefloquine in Wad Medani District, Sudan.
Topics: Animals; Antimalarials; Chloroquine; In Vitro Techniques; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinine; Sudan; Sulfadoxine | 2006 |
Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin.
Topics: Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; DNA, Protozoan; Drug Resistance, Multiple; Ethanolamines; Fluorenes; Genes, MDR; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins; Quinine; Sesquiterpenes | 2006 |
The connexin 36 blockers quinine, quinidine and mefloquine inhibit cortical spreading depression in a rat neocortical slice model in vitro.
Topics: Animals; Cell Communication; Connexins; Cortical Spreading Depression; Dose-Response Relationship, Drug; Gap Junction delta-2 Protein; Gap Junctions; Male; Mefloquine; Membrane Potentials; Models, Neurological; Neocortex; Organ Culture Techniques; Potassium Channel Blockers; Quinidine; Quinine; Rats; Rats, Sprague-Dawley | 2006 |
[A plasmodium alciparum malaria case originated from Mozambique: clues for the diagnosis and therapy].
Topics: Animals; Antimalarials; Canada; Chloroquine; Doxycycline; Drug Resistance; Erythrocytes; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Mozambique; Parasitemia; Plasmodium falciparum; Quinine; Secondary Prevention; Travel; Turkey | 2006 |
A non-radiolabeled heme-GSH interaction test for the screening of antimalarial compounds.
Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Atovaquone; Chloroquine; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Glutathione; Heme; Indicators and Reagents; Mefloquine; Methylene Blue; o-Phthalaldehyde; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Spectrometry, Fluorescence | 2007 |
The antimalarial drugs quinine, chloroquine and mefloquine are antagonists at 5-HT3 receptors.
Topics: Algorithms; Animals; Antimalarials; Binding, Competitive; Cells, Cultured; Chloroquine; Dose-Response Relationship, Drug; Electrophysiology; Female; Granisetron; In Vitro Techniques; Kinetics; Mefloquine; Models, Molecular; Oocytes; Quinine; Radioligand Assay; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Xenopus laevis | 2007 |
The in-vitro susceptibilities of Ghanaian Plasmodium falciparum to antimalarial drugs.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Resistance; Ghana; Humans; Infant; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes | 2007 |
Prevalent pfmdr1 n86y mutant Plasmodium falciparum in Madagascar despite absence of pfcrt mutant strains.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; DNA, Protozoan; Drug Resistance; Humans; Inhibitory Concentration 50; Madagascar; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prevalence; Protozoan Proteins; Quinine; Rural Population | 2007 |
Selective ambulatory management of Plasmodium falciparum malaria in paediatric refugees.
Topics: Adolescent; Ambulatory Care; Antimalarials; Atovaquone; Australia; Child; Child, Preschool; Female; Follow-Up Studies; Hospitalization; Humans; Malaria, Falciparum; Male; Mefloquine; Parasitemia; Patient Compliance; Proguanil; Quinine; Refugees | 2007 |
Mefloquine versus 3-day oral quinine-clindamycin in uncomplicated imported falciparum malaria.
Topics: Administration, Oral; Adult; Antimalarials; Clindamycin; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Quinine; Travel | 2007 |
Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Design; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Global Health; Half-Life; Humans; Lumefantrine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2007 |
Pharmacokinetic determinants of the window of selection for antimalarial drug resistance.
Topics: Algorithms; Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Computer Simulation; Drug Resistance; Malaria; Mefloquine; Models, Theoretical; Pyrimethamine; Quinine | 2008 |
Antimalarial drugs inhibit human 5-HT(3) and GABA(A) but not GABA(C) receptors.
Topics: Animals; Antimalarials; Binding, Competitive; Cells, Cultured; Chloroquine; Electrophysiology; Female; GABA-A Receptor Antagonists; Humans; Inhibitory Concentration 50; Mefloquine; Oocytes; Quinine; Receptors, GABA; Serotonin 5-HT3 Receptor Antagonists; Xenopus laevis | 2008 |
Malaria in Egypt, Saudi Arabia and Yemen: a clinical pilot study.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Chloroquine; Egypt; Female; Humans; Infant; Malaria; Male; Mefloquine; Middle Aged; Pilot Projects; Quinine; Saudi Arabia; Severity of Illness Index; Yemen | 2007 |
Drug resistance and in vitro susceptibility of Plasmodium falciparum in Thailand during 1988-2003.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Thailand | 2009 |
Monitoring of in vitro susceptibilities and molecular markers of resistance of Plasmodium falciparum isolates from Thai-Myanmar border to chloroquine, quinine, mefloquine and artesunate.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Gene Dosage; Genetic Markers; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Myanmar; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Thailand | 2010 |
[Case report: two imported Plasmodium falciparum cases].
Topics: Antimalarials; Doxycycline; Drug Resistance; Fatal Outcome; Humans; Malaria, Falciparum; Male; Mefloquine; Quinine; Respiratory Distress Syndrome; Young Adult | 2009 |
Decreased in vitro susceptibility of Plasmodium falciparum isolates to artesunate, mefloquine, chloroquine, and quinine in Cambodia from 2001 to 2007.
Topics: Antimalarials; Artemisinins; Artesunate; Cambodia; Chloroquine; Drug Resistance, Bacterial; Geographic Information Systems; In Vitro Techniques; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Oligonucleotide Array Sequence Analysis; Plasmodium falciparum; Point Mutation; Polymorphism, Single Nucleotide; Quinine | 2010 |
In vitro activities of quinine and other antimalarials and pfnhe polymorphisms in Plasmodium isolates from Kenya.
Topics: Amino Acid Sequence; Animals; Antimalarials; Drug Resistance; Humans; Kenya; Mefloquine; Membrane Transport Proteins; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Sequence Analysis, DNA; Sodium-Hydrogen Exchangers | 2010 |
Purified Plasmodium falciparum multi-drug resistance protein (PfMDR 1) binds a high affinity chloroquine analogue.
Topics: Antimalarials; Binding Sites; Chloroquine; Drug Resistance, Multiple; Mefloquine; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Protein Binding; Quinine | 2010 |
Residual antimalarial concentrations before treatment in patients with malaria from Cambodia: indication of drug pressure.
Topics: Adolescent; Adult; Antimalarials; Cambodia; Child; Child, Preschool; Chloroquine; Chromatography, Liquid; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Quinine; Quinolines; Selection, Genetic; Serum; Tandem Mass Spectrometry; Young Adult | 2010 |
In-vitro culture of Plasmodium falciparum: utility of modified (RPNI) medium for drug-sensitivity studies using SYBR Green I assay.
Topics: Antimalarials; Artemether; Artemisinins; Benzothiazoles; Chloroquine; Culture Media; Diamines; Fluorescent Dyes; Mefloquine; Organic Chemicals; Plasmodium falciparum; Quinine; Quinolines | 2011 |
Sensitivity to artemisinin, mefloquine and quinine of Plasmodium falciparum in northwestern Thailand.
Topics: Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Lethal Dose 50; Mefloquine; Plasmodium falciparum; Quinine; Thailand | 2010 |
Effects of anti-malarial drugs on the electrocardiographic QT interval modelled in the isolated perfused guinea pig heart system.
Topics: Animals; Antimalarials; Arrhythmias, Cardiac; Guinea Pigs; Heart; Heart Conduction System; Mefloquine; Phenanthrenes; Quinidine; Quinine; Time Factors | 2010 |
Artemether and artesunate show the highest efficacies in rescuing mice with late-stage cerebral malaria and rapidly decrease leukocyte accumulation in the brain.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Brain; Leukocytes; Malaria, Cerebral; Mefloquine; Mice; Parasitemia; Plasmodium berghei; Quinine | 2011 |
In vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, quinine, mefloquine and halofantrine in Abidjan (Côte d'Ivoire).
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Child; Child, Preschool; Cote d'Ivoire; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Microbial Sensitivity Tests; Middle Aged; Phenanthrenes; Plasmodium falciparum; Quinine; Young Adult | 2010 |
In vitro activity of Proveblue (methylene blue) on Plasmodium falciparum strains resistant to standard antimalarial drugs.
Topics: Amodiaquine; Antimalarials; Chloroquine; Ethanolamines; Fluorenes; Inhibitory Concentration 50; Lumefantrine; Mefloquine; Methylene Blue; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine | 2011 |
Plasmodium knowlesi reinfection in human.
Topics: Adult; Antimalarials; Artemether; Artemisinins; Blood Transfusion; Doxycycline; Ethanolamines; Fluorenes; Hemolysis; Humans; Lumefantrine; Malaria; Malaysia; Male; Mefloquine; Microscopy; Phylogeny; Plasmodium knowlesi; Polymerase Chain Reaction; Protozoan Proteins; Quinine; Recurrence | 2011 |
Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta).
Topics: Aminoquinolines; Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Chromatography, Liquid; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Macaca mulatta; Malaria; Male; Mass Spectrometry; Mefloquine; Plasma; Plasmodium cynomolgi; Primate Diseases; Quinine; Treatment Outcome | 2011 |
Quality of essential drugs in tropical countries: evaluation of antimalarial drugs in the Brazilian Health System.
Topics: Antimalarials; Brazil; Chloroquine; Chromatography, High Pressure Liquid; Drug Storage; Drugs, Essential; Humans; Mefloquine; Primaquine; Quality Control; Quinine | 2011 |
Extracellular heme enhances the antimalarial activity of artemisinin.
Topics: Antimalarials; Antioxidants; Artemisia; Artemisinins; Chloroquine; Cholesterol, LDL; Fluorescence; Heme; Hemin; Humans; Lipid Peroxidation; Mefloquine; Oxidants; Oxidation-Reduction; Plasmodium falciparum; Quinine; Tryptophan; Vitamin E | 2012 |
Discordant temporal evolution of Pfcrt and Pfmdr1 genotypes and Plasmodium falciparum in vitro drug susceptibility to 4-aminoquinolines after drug policy change in French Guiana.
Topics: Aminoquinolines; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Ethanolamines; Evolution, Molecular; Fluorenes; French Guiana; Gene Dosage; Haplotypes; Humans; Inhibitory Concentration 50; Longitudinal Studies; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Practice Guidelines as Topic; Protozoan Proteins; Quinine | 2012 |
Defining the timing of action of antimalarial drugs against Plasmodium falciparum.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chloroquine; Erythrocytes; Flow Cytometry; High-Throughput Screening Assays; Hydroxamic Acids; Inhibitory Concentration 50; Mefloquine; Merozoites; Plasmodium falciparum; Quinine; Quinolines; Schizonts; Time Factors | 2013 |
Ketoconazole, a cytochrome P(450) inhibitor can potentiate the antimalarial action of α/β arteether against MDR Plasmodium yoelii nigeriensis.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance, Multiple; Drug Synergism; Drug Therapy, Combination; Female; Humans; Ketoconazole; Liver; Malaria; Male; Mefloquine; Mice; Plasmodium falciparum; Plasmodium yoelii; Quinine | 2013 |
High-throughput analysis of antimalarial susceptibility data by the WorldWide Antimalarial Resistance Network (WWARN) in vitro analysis and reporting tool.
Topics: Amodiaquine; Antimalarials; Artemisinins; Automation, Laboratory; Chloroquine; Drug Resistance; Drug Therapy, Combination; High-Throughput Screening Assays; Internet; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine | 2013 |
Repeat polymorphisms in the low-complexity regions of Plasmodium falciparum ABC transporters and associations with in vitro antimalarial responses.
Topics: Amino Acid Motifs; Antimalarials; Artemisinins; Asparagine; Aspartic Acid; Chloroquine; Drug Resistance; Ethanolamines; Fluorenes; Gene Expression; Genome, Protozoan; Lumefantrine; Mefloquine; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine | 2013 |
Plasmodium falciparum Polymorphisms associated with ex vivo drug susceptibility and clinical effectiveness of artemisinin-based combination therapies in Benin.
Topics: Amodiaquine; Antimalarials; Artemisinins; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Inhibitory Concentration 50; Lumefantrine; Male; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Quinine; Sulfadoxine | 2014 |
Four years' monitoring of in vitro sensitivity and candidate molecular markers of resistance of Plasmodium falciparum to artesunate-mefloquine combination in the Thai-Myanmar border.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Resistance; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Seasons; Thailand; Time Factors | 2014 |
In vitro susceptibility of Plasmodium vivax to antimalarials in Colombia.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chloroquine; Colombia; Drug Resistance; Malaria, Vivax; Mefloquine; Parasitic Sensitivity Tests; Plasmodium vivax; Quinine | 2014 |
Role of Pfmdr1 in in vitro Plasmodium falciparum susceptibility to chloroquine, quinine, monodesethylamodiaquine, mefloquine, lumefantrine, and dihydroartemisinin.
Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Biological Transport; Child; Chloroquine; Drug Resistance; Erythrocytes; Ethanolamines; Female; Fluorenes; Gene Expression; Haplotypes; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Quinine; Senegal | 2014 |
Alkoxide coordination of iron(III) protoporphyrin IX by antimalarial quinoline methanols: a key interaction observed in the solid-state and solution.
Topics: Acetonitriles; Antimalarials; Cinchona Alkaloids; Coordination Complexes; Ferric Compounds; Mefloquine; Protoporphyrins; Quinidine; Quinine; Spectrophotometry; Thermodynamics; X-Ray Diffraction | 2015 |
Gap junctions between CA3 pyramidal cells contribute to network synchronization in neonatal hippocampus.
Topics: Action Potentials; Animals; CA3 Region, Hippocampal; Carbenoxolone; Flufenamic Acid; Gap Junctions; Mefloquine; Neurotransmitter Agents; Patch-Clamp Techniques; Pyramidal Cells; Quinine; Rats, Wistar; Tissue Culture Techniques | 2016 |
Absence of Association between Polymorphisms in the RING E3 Ubiquitin Protein Ligase Gene and Ex Vivo Susceptibility to Conventional Antimalarial Drugs in Plasmodium falciparum Isolates from Dakar, Senegal.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Doxycycline; Ethanolamines; Fluorenes; Lumefantrine; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Quinine; Quinolines; Senegal; Ubiquitin-Protein Ligases | 2016 |
In vitro sensitivity of antimalarial drugs and correlation with clinico-parasitological response following treatment with a 3-day artesunate-mefloquine combination in patients with falciparum malaria along the Thai-Myanmar border.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Myanmar; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Thailand; Young Adult | 2017 |
Association between Polymorphisms in the Pf
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Asparagine; ATP-Binding Cassette Transporters; Chloroquine; Doxycycline; Drug Resistance; Ethanolamines; Fluorenes; Gene Expression; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Protein Isoforms; Protozoan Proteins; Quinine; Quinolines; Repetitive Sequences, Amino Acid; Senegal | 2017 |
Heterologous Expression of a Novel Drug Transporter from the Malaria Parasite Alters Resistance to Quinoline Antimalarials.
Topics: Amino Acid Transport Systems; Amodiaquine; Animals; Antimalarials; Biological Transport; Chloroquine; Conserved Sequence; Drug Resistance; Gene Expression; Humans; Mefloquine; Mutation; Plasmodium chabaudi; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinine; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transgenes | 2018 |
Topics: Anti-Bacterial Agents; Antimalarials; Artemether; Artemisinins; Atovaquone; Azithromycin; Chloroquine; Doxycycline; Ethanolamines; Fluorenes; Humans; India; Lumefantrine; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 2017 |
Nanomolar binding affinity of quinine-based antimalarial compounds by the cocaine-binding aptamer.
Topics: Amodiaquine; Antimalarials; Aptamers, Nucleotide; Binding Sites; Chloroquine; Cocaine; Ligands; Mefloquine; Primaquine; Quinine; Thermodynamics | 2018 |
Absence of
Topics: Antimalarials; Artemether; Artesunate; Brazil; Drug Combinations; Drug Resistance; Epidemiological Monitoring; Gene Expression; Genetic Markers; Genotyping Techniques; Humans; Kelch Repeat; Malaria, Falciparum; Mefloquine; Molecular Epidemiology; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine | 2018 |
Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay.
Topics: Biological Assay; Mefloquine; Models, Molecular; Molecular Targeted Therapy; Plasmodium falciparum; Proteome; Purine-Nucleoside Phosphorylase; Quinine; Reproducibility of Results; Temperature | 2019 |
Ex-vivo Sensitivity of Plasmodium falciparum to Common Anti-malarial Drugs: The Case of Kéniéroba, a Malaria Endemic Village in Mali.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance; Endemic Diseases; Humans; Infant; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mali; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 2020 |
Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in Northern Uganda.
Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Lumefantrine; Mefloquine; Plasmodium falciparum; Quinine; Uganda | 2021 |