Page last updated: 2024-08-23

mefloquine and lumefantrine

mefloquine has been researched along with lumefantrine in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (3.57)	18.2507
2000's	16 (28.57)	29.6817
2010's	33 (58.93)	24.3611
2020's	5 (8.93)	2.80

Authors

Authors	Studies
Girdwood, SC; Mott, BT; Nenortas, E; Posner, GH; Shapiro, TA; Slack, RD; Sullivan, D; Tripathi, A; Triphati, A; Woodard, LE	1
Biamonte, MA; Le Roch, KG; Wanner, J	1
Avery, VM; Buchholz, M; Delves, MJ; Duffy, S; Fischli, C; Held, J; Knaab, TC; Kuna, K; Kurz, T; Lehmann, U; Leven, M; Lungerich, B; Meister, S; Meitzner, D; Mordmüller, B; Stahlke, P; Winzeler, EA; Wittlin, S	1
Bane, CE; Black, C; Butler, K; Caridha, D; Cooper, RA; Dodean, RA; Gaona, H; Gaynor-Ohnstad, L; Huezo, SJ; Kancharla, P; Kelly, JX; Kreishman-Deitrick, M; Leed, SE; Li, Q; Li, Y; Lin, H; Luong, TL; Marcsisin, S; Melendez, V; Nolan, C; Olmeda, R; Potter, B; Pou, S; Rasmussen, SA; Read, L; Riscoe, MK; Roncal, N; Sciotti, RJ; Smilkstein, MJ; Sousa, J; Stephens, MT; Tan, JC; Vesely, B; Vuong, C; Winter, RW; Xie, L; Zeng, Q; Zhang, J; Zhang, P	1
Brockman, A; Gathmann, I; Gemperli, B; Looareesuwan, S; Luxemburger, C; Nosten, F; Royce, C; Slight, T; van Vugt, M; White, NJ	1
Chalermrut, K; Chokejindachai, W; Gathmann, I; Gemperli, B; Looareesuwan, S; Royce, C; Wernsdorfer, W; Wilairatana, P	1
Amklad, I; Looareesuwan, S; Rojanawatsirivej, C; Vijaykadga, S; Wilairatna, P	1
Stingl, P	1
Annerberg, A; Barends, M; Keola, S; Khanthavong, M; Lindegårdh, N; Mayxay, M; Newton, PN; Phetsouvanh, R; Phompida, S; Pongvongsa, T; White, NJ; Yapom, R	1
Annerberg, A; Christophel, EM; Dittrich, S; Jelinek, T; Lindegardh, N; Monti, F; Phetsouvanh, R; Phompida, S; Stohrer, JM; Thongpaseuth, V; Vanisaveth, V	1
Pilz, JB; Rojanawatsirivet, C; Sirichaisinthop, J; Wernsdorfer, G; Wernsdorfer, WH; Wiedermann, G	1
Bangali, AM; Barends, M; Das, S; Faiz, AM; Kamal, M; Liem, L; Maung, UA; Peters, A; Rahman, M; Rahman, MR; van den Broek, IV	1
Garner, P; Jones, K; Taylor-Robinson, D	1
Ashley, EA; Brockman, A; Hutagalung, R; Jelinek, T; McGready, R; Nosten, FH; Paiphun, L; Singhasivanon, P; Thwai, KL; White, NJ	1
Fidock, DA; Krishna, S; Sidhu, AB; Uhlemann, AC; Valderramos, JC; Valderramos, SG	1
Annerberg, A; Christophel, EM; Denis, MB; Fandeur, T; Lim, P; Lindegardh, N; Ringwald, P; Socheat, D; Top, SN; Tsuyuoka, R; Yi, P	1
Anderson, T; Barends, M; Brockman, A; Jaidee, A; Mayxay, M; Nair, S; Newton, PN; Phetsouvanh, R; Phompida, S; Pongvongsa, T; Sudimack, D; White, NJ	1
Dieng, Y; Faye, B; Faye, O; Gaye, O; Ndiaye, D; Ndiaye, JL	1
Nyunt, MM; Plowe, CV	1
Bustamante, LY; East, JM; Krishna, S; Toovey, S; Uhlemann, AC	1
Coulibaly, M; Diallo, A; Diawara, SI; Dicko, A; Djimde, A; Doumbo, OK; Guindo, O; Kone, M; Maiga, H; Niambele, MB; Sagara, I; Sissoko, M	1
Donegan, S; Garner, P; Olliaro, P; Sinclair, D; Zani, B	1
Kano, S	1
Amalvict, R; Baret, E; Briolant, S; Charras, S; Feraud, M; Henry, M; Huyghues des Etages, E; Pascual, A; Pradines, B; Rogier, C	1
Angelino, E; Barnes, KG; Becker, JS; Birren, BW; Cortese, JF; Daniels, RF; Eskin, E; Furlotte, NA; Grossman, SR; Happi, C; Hartl, DL; Johnson, CA; Kang, HM; Karlsson, EK; Lander, ES; Lukens, AK; Mboup, S; Milner, DA; Ndiaye, D; Neafsey, DE; Park, DJ; Rosen, DM; Sabeti, PC; Sarr, O; Schaffner, SF; Shlyakhter, I; Van Tyne, D; Volkman, SK; Wiegand, RC; Wirth, DF; Yamins, D	1
Björkman, A; Ferreira, PE; Gil, JP; Jörnhagen, L; Kone, A; Malmberg, M; Nosten, F; Petzold, M; Schmidt, BA; Veiga, MI	1
Borges, S; Cravo, P; Creasey, A; Fawcett, R; Hunt, P; Martinelli, A; Modrzynska, K; Rodrigues, L	1
Chin, LC; Fong, MY; Lau, YL; Noraishah, MA; Rohela, M; Tan, LH	1
Gil, JP; Piedade, R	1
Ensom, MH; Wilby, KJ	1
Cowman, AF; Healer, J; Uboldi, AD; Van Tyne, D; Wirth, DF	1
Akala, HM; Andagalu, B; Bulimo, W; Cheruiyot, A; Eyase, FL; Ingasia, L; Johnson, JD; Juma, D; Kamau, E; Okudo, C; Omondi, A; Schnabel, D; Walsh, DS; Wanja, E; Waters, NC; Yeda, R	1
Anderson, TJ; Jamsen, KM; Nair, S; Nosten, F; Price, RN; Simpson, JA; White, NJ; Woodrow, C; Zaloumis, S	1
Abdi, AI; Kiara, SM; Mwai, L; Nzila, A; Ochola-Oyier, LI; Okombo, J; Pole, L; Sutherland, CJ	1
Aubouy, A; Dahlström, S; Deloron, P; Ezinmègnon, S; Faucher, JF; Houzé, P; Houzé, S; Kendjo, E; Le Bras, J; Maïga-Ascofaré, O; Massougbodji, A; Wakpo, A	1
Burkholder, B; Bustos, MD; Delacollette, C; Wongsrichanalai, C	1
Bukirwa, H; Kramer, CV; Nair, S; Sinclair, D; Tharyan, P; Unnikrishnan, B	1
Cui, L; Gupta, B; Miao, J; Sun, L; Wang, Z; Xu, S; Yang, Z	1
Baret, E; Bercion, R; Camara, C; Diatta, B; Diémé, Y; Fall, B; Fall, KB; Fall, M; Mbaye, PS; Nakoulima, A; Pascual, A; Pradines, B; Wade, B; Wurtz, N	1
Mannemala, SS; Nagarajan, JS	1
Barnwell, JW; Goldman, I; Juma, E; Kariuki, S; Komino, F; Lucchi, NW; Okoth, SA; Onyona, P; Shi, YP; Udhayakumar, V; Wiegand, RE	1
Cabrera, M; Cui, L	1
Amalvict, R; Benoit, N; Diatta, B; Diawara, S; Diémé, Y; Fall, B; Fall, M; Gendrot, M; Madamet, M; Nakoulima, A; Pradines, B; Wade, B; Wade, KA	1
Ackermann, I; Aubin, F; Carn, G; Gesase, S; Lusingu, JPA; Mnkande, E; Mrango, Z; Mtoro, A; Ngocho, JS; Ogutu, B; Onyango, KO; Ouedraogo, A; Sirima, SB; Strub, N; Vanraes, J; Yaro, JB	1
Amalvict, R; Benoit, N; Briolant, S; Diatta, B; Diawara, S; Diémé, Y; Fall, B; Fall, M; Gendrot, M; Kounta, MB; Madamet, M; Nakoulima, A; Pradines, B; Wade, B; Wade, KA	1
Byaruhanga, O; Ceja, FG; Conrad, MD; Cooper, RA; Katairo, T; Nsobya, SL; Rasmussen, SA; Rosenthal, PJ; Tumwebaze, PK	1
Annan, K; Ansah, C; Forkuo, AD; Gyan, B; Mancama, D; Mensah, KB; Theron, A; Wright, CW	1
Agarwal, P; Anvikar, AR; Pillai, CR; Srivastava, K	1
Hine, P; Pryce, J	1
Björkman, A; Garcia, S; Humphreys, GS; Otienoburu, SD; Srisutham, S; Suay, I; Thomas, NV	1
Chy, S; Felger, I; Hastings, I; Hodel, EM; Jones, S; Kay, K; Mbituyumuremyi, A; Menard, D; Uwimana, A	1
Bah, S; Dabitao, D; Dama, S; Diakité, M; Diakité, SAS; Doumbia, S; Doumbouya, M; Guindo, MA; Keita, B; Konaté, DS; Sangaré, M; Sanogo, I; Traoré, K	1
Carvalho, LJM; Nugraha, AB; Sivakumar, T; Tuvshintulga, B; Yokoyama, N	1
Caleon, RL; Gadalla, NB; Lane, KD; Liu, A; Mu, J; Rahman, RS; Sá, JM; Wellems, TE; Windle, ST	1
Anywar, DA; Auma, MA; Balikagala, B; Emoto, S; Fukuda, N; Hashimoto, M; Hirai, M; Horii, T; Ikeda, M; Kataoka, M; Katuro, OT; Kimura, E; Mita, T; Mori, T; Obwoya, PS; Odongo-Aginya, EI; Ogwang, M; Opio, W; Palacpac, NMQ; Sakurai-Yatsushiro, M; Sekihara, M; Tachibana, SI; Yamauchi, M; Yatsushiro, S	1
Corry, B; Martin, RE; Richards, SN; Shafik, SH	1

Reviews

10 review(s) available for mefloquine and lumefantrine

Article	Year
Recent advances in malaria drug discovery. Bioorganic & medicinal chemistry letters, 2013, May-15, Volume: 23, Issue:10 Topics: Animals; Antimalarials; Drug Discovery; Humans; Liver; Liver Transplantation; Malaria; Molecular Structure	2013
[Malaria: prophylaxis, treatment, stand-by medication. A single mosquito bite suffices]. MMW Fortschritte der Medizin, 2004, Jun-17, Volume: 146, Issue:25 Topics: Adult; Antimalarials; Artemether; Artemisinins; Atovaquone; Chloroquine; Climate; Doxycycline; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria; Male; Mefloquine; Naphthoquinones; Pregnancy; Proguanil; Risk Factors; Self Medication; Sesquiterpenes; Time Factors; Travel	2004
Malaria: uncomplicated, caused by Plasmodium falciparum. Clinical evidence, 2005, Issue:13 Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Mefloquine; Proguanil; Pyrimethamine; Sesquiterpenes; Sulfadoxine	2005
Artemisinin-based combination therapy for treating uncomplicated malaria. The Cochrane database of systematic reviews, 2009, Jul-08, Issue:3 Topics: Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Sulfadoxine	2009
Artemisinin-based combination therapies and their introduction in Japan. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2010, Volume: 16, Issue:6 Topics: Animals; Antimalarials; Artemether; Artemisia annua; Artemisinins; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Japan; Lumefantrine; Malaria, Cerebral; Malaria, Falciparum; Mefloquine; Plasmodium falciparum	2010
The pharmacogenetics of antimalaria artemisinin combination therapy. Expert opinion on drug metabolism & toxicology, 2011, Volume: 7, Issue:10 Topics: Aminoquinolines; Antimalarials; Artemisinins; Artesunate; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Drug Combinations; Drug Resistance; Ethanolamines; Evidence-Based Medicine; Fluorenes; Genetic Markers; Humans; Lumefantrine; Malaria, Falciparum; Mefloquine; Pharmacogenetics; Plasmodium falciparum; Polymorphism, Single Nucleotide	2011
Pharmacokinetics of antimalarials in pregnancy: a systematic review. Clinical pharmacokinetics, 2011, Nov-01, Volume: 50, Issue:11 Topics: Anti-Bacterial Agents; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Pyrimethamine; Quinine; Sulfadoxine	2011
Monitoring antimalarial drug efficacy in the Greater Mekong Subregion: an overview of in vivo results from 2008 to 2010. The Southeast Asian journal of tropical medicine and public health, 2013, Volume: 44 Suppl 1 Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Directly Observed Therapy; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Quinolines	2013
Artesunate plus pyronaridine for treating uncomplicated Plasmodium falciparum malaria. The Cochrane database of systematic reviews, 2014, Mar-04, Issue:3 Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Liver; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Randomized Controlled Trials as Topic	2014
Pyronaridine-artesunate for treating uncomplicated Plasmodium falciparum malaria. The Cochrane database of systematic reviews, 2019, 01-08, Volume: 1 Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Drug Therapy, Combination; Humans; Liver; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Randomized Controlled Trials as Topic	2019

Trials

12 trial(s) available for mefloquine and lumefantrine

Article	Year
Randomized comparison of artemether-benflumetol and artesunate-mefloquine in treatment of multidrug-resistant falciparum malaria. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:1 Topics: Adolescent; Adult; Aged; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Double-Blind Method; Drug Resistance, Multiple; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Prospective Studies; Sesquiterpenes; Treatment Outcome	1998
A randomized, double-blind, comparative trial of a new oral combination of artemether and benflumetol (CGP 56697) with mefloquine in the treatment of acute Plasmodium falciparum malaria in Thailand. The American journal of tropical medicine and hygiene, 1999, Volume: 60, Issue:2 Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Double-Blind Method; Drug Administration Schedule; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Mefloquine; Middle Aged; Outcome Assessment, Health Care; Sesquiterpenes; Treatment Failure	1999
Monitoring the therapeutic efficacy of antimalarials against uncomplicated falciparum malaria in Thailand. The Southeast Asian journal of tropical medicine and public health, 2003, Volume: 34, Issue:3 Topics: Adolescent; Adult; Aged; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Fluorenes; Health Policy; Humans; Lumefantrine; Malaria, Falciparum; Mefloquine; Middle Aged; Primaquine; Sesquiterpenes; Statistics, Nonparametric; Thailand; Treatment Outcome	2003
Randomized comparison of chloroquine plus sulfadoxine-pyrimethamine versus artesunate plus mefloquine versus artemether-lumefantrine in the treatment of uncomplicated falciparum malaria in the Lao People's Democratic Republic. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, Oct-15, Volume: 39, Issue:8 Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Laos; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Pyrimethamine; Sesquiterpenes; Sulfadoxine	2004
Therapeutic efficacy of artemether-lumefantrine and artesunate-mefloquine for treatment of uncomplicated Plasmodium falciparum malaria in Luang Namtha Province, Lao People's Democratic Republic. Tropical medicine & international health : TM & IH, 2004, Volume: 9, Issue:11 Topics: Acute Disease; Adolescent; Adult; Aged; Antimalarials; Artemether; Artemisinins; Artesunate; Biological Availability; Child; Child, Preschool; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Korea; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Parasitemia; Sesquiterpenes; Treatment Outcome	2004
Efficacy of chloroquine + sulfadoxine--pyrimethamine, mefloquine + artesunate and artemether + lumefantrine combination therapies to treat Plasmodium falciparum malaria in the Chittagong Hill Tracts, Bangladesh. Transactions of the Royal Society of Tropical Medicine and Hygiene, 2005, Volume: 99, Issue:10 Topics: Adolescent; Antimalarials; Artemether; Artemisinins; Artesunate; Bangladesh; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome	2005
A randomized trial of artemether-lumefantrine versus mefloquine-artesunate for the treatment of uncomplicated multi-drug resistant Plasmodium falciparum on the western border of Thailand. Malaria journal, 2005, Sep-22, Volume: 4 Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Drug Resistance, Multiple; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Sesquiterpenes; Thailand	2005
Efficacy of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in northwest Cambodia. Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:12 Topics: Acute Disease; Adolescent; Adult; Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Dietary Supplements; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Sesquiterpenes; Treatment Failure; Treatment Outcome	2006
Efficacy and tolerability of four antimalarial combinations in the treatment of uncomplicated Plasmodium falciparum malaria in Senegal. Malaria journal, 2007, Jun-14, Volume: 6 Topics: Adolescent; Adult; Aged; Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Fluorenes; Follow-Up Studies; Humans; Infant; Lumefantrine; Malaria, Falciparum; Mefloquine; Middle Aged; Plasmodium falciparum; Pyrimethamine; Senegal; Sesquiterpenes; Sulfadoxine; Treatment Outcome	2007
A randomized trial of artesunate-mefloquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Mali. The American journal of tropical medicine and hygiene, 2008, Volume: 79, Issue:5 Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Base Sequence; DNA Primers; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Mali; Mefloquine; Plasmodium falciparum; Polymerase Chain Reaction; Treatment Outcome	2008
Comparison of artesunate-mefloquine and artemether-lumefantrine fixed-dose combinations for treatment of uncomplicated Plasmodium falciparum malaria in children younger than 5 years in sub-Saharan Africa: a randomised, multicentre, phase 4 trial. The Lancet. Infectious diseases, 2016, Volume: 16, Issue:10 Topics: Africa South of the Sahara; Antimalarials; Artemether; Artemisinins; Artesunate; Child, Preschool; Ethanolamines; Female; Fluorenes; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Patient Safety; Polymerase Chain Reaction	2016
Changing Antimalarial Drug Sensitivities in Uganda. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:12 Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Aspartic Acid Endopeptidases; Child; Child, Preschool; Chloroquine; Drug Resistance; Ethanolamines; Female; Fluorenes; Gene Expression; Humans; Infant; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Quinolines; Uganda; Young Adult	2017

Other Studies

34 other study(ies) available for mefloquine and lumefantrine

Article	Year
Malaria-infected mice are completely cured by one 6 mg/kg oral dose of a new monomeric trioxane sulfide combined with mefloquine. Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1 Topics: Administration, Oral; Anilides; Animals; Antimalarials; Drug Therapy, Combination; Malaria; Mefloquine; Mice; Parasitemia; Plasmodium berghei; Stereoisomerism; Structure-Activity Relationship; Sulfides; Sulfones; Sulfoxides	2012
3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally. Journal of medicinal chemistry, 2017, 07-27, Volume: 60, Issue:14 Topics: Amides; Animals; Antimalarials; Hep G2 Cells; Humans; Hydrazones; Malaria; Mice; Phenanthrenes; Plasmodium berghei; Stereoisomerism; Structure-Activity Relationship	2017
Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials. Journal of medicinal chemistry, 2019, 04-11, Volume: 62, Issue:7 Topics: Acridones; Animals; Antimalarials; Disease Models, Animal; Drug Discovery; Hep G2 Cells; Humans; Malaria; Mice; Plasmodium; Species Specificity; Structure-Activity Relationship	2019
In vitro sensitivity of Plasmodium falciparum to lumefantrine in north-western Thailand. Wiener klinische Wochenschrift, 2004, Volume: 116 Suppl 4 Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Data Interpretation, Statistical; Drug Resistance, Multiple; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Sesquiterpenes; Thailand	2004
Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin. The Journal of infectious diseases, 2006, Aug-15, Volume: 194, Issue:4 Topics: Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; DNA, Protozoan; Drug Resistance, Multiple; Ethanolamines; Fluorenes; Genes, MDR; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins; Quinine; Sesquiterpenes	2006
In vitro antimalarial drug susceptibility and pfcrt mutation among fresh Plasmodium falciparum isolates from the Lao PDR (Laos). The American journal of tropical medicine and hygiene, 2007, Volume: 76, Issue:2 Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Resistance; Ethanolamines; Female; Fluorenes; Humans; Inhibitory Concentration 50; Laos; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Protozoan Proteins; Sesquiterpenes	2007
Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance. Clinical pharmacology and therapeutics, 2007, Volume: 82, Issue:5 Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Design; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Global Health; Half-Life; Humans; Lumefantrine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine	2007
Effect of artemisinins and amino alcohol partner antimalarials on mammalian sarcoendoplasmic reticulum calcium adenosine triphosphatase activity. Basic & clinical pharmacology & toxicology, 2008, Volume: 103, Issue:3 Topics: Animals; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Ethanolamines; Fluorenes; In Vitro Techniques; Isoenzymes; Lumefantrine; Mefloquine; Rabbits; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stereoisomerism	2008
In vitro activity of Proveblue (methylene blue) on Plasmodium falciparum strains resistant to standard antimalarial drugs. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:5 Topics: Amodiaquine; Antimalarials; Chloroquine; Ethanolamines; Fluorenes; Inhibitory Concentration 50; Lumefantrine; Mefloquine; Methylene Blue; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine	2011
Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum. PLoS genetics, 2011, Volume: 7, Issue:4 Topics: Antimalarials; Drug Resistance; Ethanolamines; Fluorenes; Gene Dosage; Gene Expression; Genetic Association Studies; Genetic Loci; Genetic Variation; Genotype; Haplotypes; Linkage Disequilibrium; Lumefantrine; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Polymorphism, Single Nucleotide; Selection, Genetic	2011
Novel polymorphisms in Plasmodium falciparum ABC transporter genes are associated with major ACT antimalarial drug resistance. PloS one, 2011, Volume: 6, Issue:5 Topics: Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Base Sequence; Drug Resistance; Ethanolamines; Fluorenes; Gene Frequency; Genotype; Haplotypes; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins	2011
Genomewide scan reveals amplification of mdr1 as a common denominator of resistance to mefloquine, lumefantrine, and artemisinin in Plasmodium chabaudi malaria parasites. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:10 Topics: Antimalarials; Artemisinins; Base Sequence; Chromosome Mapping; Drug Resistance, Multiple; Ethanolamines; Fluorenes; Genetic Linkage; Genome, Protozoan; Lumefantrine; Malaria; Mefloquine; Multidrug Resistance-Associated Proteins; Plasmodium chabaudi; Sequence Analysis, DNA	2011
Plasmodium knowlesi reinfection in human. Emerging infectious diseases, 2011, Volume: 17, Issue:7 Topics: Adult; Antimalarials; Artemether; Artemisinins; Blood Transfusion; Doxycycline; Ethanolamines; Fluorenes; Hemolysis; Humans; Lumefantrine; Malaria; Malaysia; Male; Mefloquine; Microscopy; Phylogeny; Plasmodium knowlesi; Polymerase Chain Reaction; Protozoan Proteins; Quinine; Recurrence	2011
Modulation of PF10_0355 (MSPDBL2) alters Plasmodium falciparum response to antimalarial drugs. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7 Topics: Antimalarials; Base Sequence; DNA Copy Number Variations; Drug Resistance; Ethanolamines; Fluorenes; Gene Dosage; Gene Frequency; Genes, Protozoan; Lumefantrine; Malaria, Falciparum; Mefloquine; Mutation; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Sequence Analysis, DNA	2013
The role of Pfmdr1 and Pfcrt in changing chloroquine, amodiaquine, mefloquine and lumefantrine susceptibility in western-Kenya P. falciparum samples during 2008-2011. PloS one, 2013, Volume: 8, Issue:5 Topics: Amodiaquine; Antimalarials; Chloroquine; DNA, Protozoan; Drug Resistance; Ethanolamines; Fluorenes; Haplotypes; Humans; Inhibitory Concentration 50; Kenya; Lumefantrine; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Retrospective Studies	2013
Nonlinear mixed-effects modelling of in vitro drug susceptibility and molecular correlates of multidrug resistant Plasmodium falciparum. PloS one, 2013, Volume: 8, Issue:7 Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Ethanolamines; Fluorenes; Lumefantrine; Mefloquine; Models, Statistical; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Protozoan Proteins	2013
Repeat polymorphisms in the low-complexity regions of Plasmodium falciparum ABC transporters and associations with in vitro antimalarial responses. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12 Topics: Amino Acid Motifs; Antimalarials; Artemisinins; Asparagine; Aspartic Acid; Chloroquine; Drug Resistance; Ethanolamines; Fluorenes; Gene Expression; Genome, Protozoan; Lumefantrine; Mefloquine; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine	2013
Plasmodium falciparum Polymorphisms associated with ex vivo drug susceptibility and clinical effectiveness of artemisinin-based combination therapies in Benin. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:1 Topics: Amodiaquine; Antimalarials; Artemisinins; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Inhibitory Concentration 50; Lumefantrine; Male; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Quinine; Sulfadoxine	2014
Plasmodium falciparum multidrug resistance protein 1 (pfmrp1) gene and its association with in vitro drug susceptibility of parasite isolates from north-east Myanmar. The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:8 Topics: Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Chloroquine; Drug Resistance; Ethanolamines; Fluorenes; Geography; Humans; Lumefantrine; Malaria, Falciparum; Mefloquine; Multidrug Resistance-Associated Proteins; Mutation; Myanmar; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Selection, Genetic; Sequence Analysis, DNA	2014
Role of Pfmdr1 in in vitro Plasmodium falciparum susceptibility to chloroquine, quinine, monodesethylamodiaquine, mefloquine, lumefantrine, and dihydroartemisinin. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:12 Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Biological Transport; Child; Chloroquine; Drug Resistance; Erythrocytes; Ethanolamines; Female; Fluorenes; Gene Expression; Haplotypes; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Quinine; Senegal	2014
Development and validation of a generic liquid chromatographic method for the simultaneous determination of five commonly used antimalarial drugs: Application to pharmaceutical formulations and human plasma. Journal of separation science, 2015, Volume: 38, Issue:9 Topics: Antimalarials; Artemether; Artemisinins; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Ethanolamines; Fluorenes; Healthy Volunteers; Humans; Lumefantrine; Mefloquine; Pyrimethamine; Reproducibility of Results; Sulfadoxine; Tablets	2015
In Vitro and Molecular Surveillance for Antimalarial Drug Resistance in Plasmodium falciparum Parasites in Western Kenya Reveals Sustained Artemisinin Sensitivity and Increased Chloroquine Sensitivity. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:12 Topics: Alleles; Amodiaquine; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance; Epidemiological Monitoring; Ethanolamines; Fluorenes; Gene Dosage; Gene Expression; Genotype; Humans; Kenya; Lumefantrine; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins	2015
In Vitro Activities of Primaquine-Schizonticide Combinations on Asexual Blood Stages and Gametocytes of Plasmodium falciparum. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:12 Topics: Antimalarials; Benzothiazoles; Chloroquine; Diamines; Drug Combinations; Drug Interactions; Erythrocytes; Ethanolamines; Flow Cytometry; Fluorenes; Humans; Lumefantrine; Mefloquine; Organic Chemicals; Parasitic Sensitivity Tests; Plasmodium falciparum; Primaquine; Quinolines; Sporozoites; Trophozoites	2015
Absence of Association between Polymorphisms in the RING E3 Ubiquitin Protein Ligase Gene and Ex Vivo Susceptibility to Conventional Antimalarial Drugs in Plasmodium falciparum Isolates from Dakar, Senegal. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8 Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Doxycycline; Ethanolamines; Fluorenes; Lumefantrine; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Quinine; Quinolines; Senegal; Ubiquitin-Protein Ligases	2016
Association between Polymorphisms in the Pf Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:3 Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Asparagine; ATP-Binding Cassette Transporters; Chloroquine; Doxycycline; Drug Resistance; Ethanolamines; Fluorenes; Gene Expression; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Protein Isoforms; Protozoan Proteins; Quinine; Quinolines; Repetitive Sequences, Amino Acid; Senegal	2017
In vitro anti-malarial interaction and gametocytocidal activity of cryptolepine. Malaria journal, 2017, 12-28, Volume: 16, Issue:1 Topics: Alkaloids; Antimalarials; Chloroquine; Ethanolamines; Fluorenes; Gametogenesis; Ghana; Humans; Indole Alkaloids; Life Cycle Stages; Lumefantrine; Malaria; Malaria, Falciparum; Mefloquine; Plant Extracts; Plasmodium falciparum; Quinolines	2017
The Indian journal of medical research, 2017, Volume: 146, Issue:5 Topics: Anti-Bacterial Agents; Antimalarials; Artemether; Artemisinins; Atovaquone; Azithromycin; Chloroquine; Doxycycline; Ethanolamines; Fluorenes; Humans; India; Lumefantrine; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine; Quinolines	2017
An online mapping database of molecular markers of drug resistance in Plasmodium falciparum: the ACT Partner Drug Molecular Surveyor. Malaria journal, 2019, Jan-18, Volume: 18, Issue:1 Topics: Amodiaquine; Antimalarials; Databases as Topic; DNA Copy Number Variations; Drug Resistance, Multiple; Lumefantrine; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Online Systems; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins	2019
Improving Methods for Analyzing Antimalarial Drug Efficacy Trials: Molecular Correction Based on Length-Polymorphic Markers Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:9 Topics: Algorithms; Antigens, Protozoan; Antimalarials; Artemisinins; Biomarkers; Clinical Trials as Topic; Gene Expression; Humans; Lumefantrine; Malaria, Falciparum; Mefloquine; Merozoite Surface Protein 1; Models, Statistical; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Restriction Fragment Length; Protozoan Proteins; Quinolines; Time Factors; Treatment Outcome	2019
Ex-vivo Sensitivity of Plasmodium falciparum to Common Anti-malarial Drugs: The Case of Kéniéroba, a Malaria Endemic Village in Mali. Drugs in R&D, 2020, Volume: 20, Issue:3 Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance; Endemic Diseases; Humans; Infant; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mali; Mefloquine; Plasmodium falciparum; Quinine; Quinolines	2020
Activities of artesunate-based combinations and tafenoquine against Babesia bovis in vitro and Babesia microti in vivo. Parasites & vectors, 2020, Jul-20, Volume: 13, Issue:1 Topics: Aminoquinolines; Animals; Antimalarials; Artesunate; Babesia bovis; Babesia microti; Babesiosis; Disease Models, Animal; Drug Combinations; In Vitro Techniques; Lumefantrine; Mefloquine; Methylene Blue; Mice; Mice, Inbred BALB C	2020
Evidence for linkage of pfmdr1, pfcrt, and pfk13 polymorphisms to lumefantrine and mefloquine susceptibilities in a Plasmodium falciparum cross. International journal for parasitology. Drugs and drug resistance, 2020, Volume: 14 Topics: Antimalarials; Cambodia; Drug Resistance; Ethanolamines; Fluorenes; Ghana; Humans; Lumefantrine; Malaria, Falciparum; Mefloquine; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Protozoan Proteins	2020
Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in Northern Uganda. Parasitology international, 2021, Volume: 81 Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Lumefantrine; Mefloquine; Plasmodium falciparum; Quinine; Uganda	2021
Mechanistic basis for multidrug resistance and collateral drug sensitivity conferred to the malaria parasite by polymorphisms in PfMDR1 and PfCRT. PLoS biology, 2022, Volume: 20, Issue:5 Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Drug Resistance, Multiple; Lumefantrine; Malaria, Falciparum; Mefloquine; Multidrug Resistance-Associated Proteins; Parasites; Plasmodium falciparum; Protein Isoforms; Protozoan Proteins	2022