Compounds > mefenamic acid

mefenamic acid and zomepirac

mefenamic acid has been researched along with zomepirac in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (31.25)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (18.75)	29.6817
2010's	7 (43.75)	24.3611
2020's	1 (6.25)	2.80

Authors

Authors	Studies
Chang, TK; Ensom, MH; Kiang, TK	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T	1
Kumar, M; Sinha, VR; Thareja, S	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Kalgutkar, AS	1
Ellis, HD; Wilcock, SE; Zaman, SA	1
Akamine, A; Aono, M; Haraga, Y; Honda, N; Kaida, H; Kishi, T; Maeda, K; Nagamine, N; Onimura, K; Yamamoto, J	1
Kumar, K; Laing, GS; Peters, K; Yates, DW	1
Court, H; Volans, GN	1
Valdez, EV	1
Atherton, J; Bauman, J; Kohl, C; Lam, W; Lou, Z; Mutlib, A; Reily, M; Walker, GS	1
Derry, S; McQuay, HJ; Moll, R; Moore, RA	1
Chai, MZ; Flanagan, JU; Squire, CJ; Teague, RM; Turnbull, AP; Yosaatmadja, Y	1

Reviews

2 review(s) available for mefenamic acid and zomepirac

Article	Year
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
Single dose oral mefenamic acid for acute postoperative pain in adults. The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3 Topics: Acute Disease; Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Mefenamic Acid; Pain, Postoperative; Randomized Controlled Trials as Topic; Sulfonamides; Tolmetin	2011

Trials

3 trial(s) available for mefenamic acid and zomepirac

Article	Year
Cold and performance: the effects of information load, analgesics, and the rate of cooling. Aviation, space, and environmental medicine, 1985, Volume: 56, Issue:3 Topics: Adult; Analgesics; Body Temperature; Cold Temperature; Humans; Intelligence Tests; Male; Mefenamic Acid; Reaction Time; Stress, Physiological; Task Performance and Analysis; Time Factors; Tolmetin	1985
[A preliminary study on the effective dose and safety of zomepirac sodium. Pain following minor surgery and tooth extraction in the field of dentistry]. Nihon Shishubyo Gakkai kaishi, 1983, Volume: 25, Issue:2 Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Humans; Mefenamic Acid; Middle Aged; Mouth; Pain, Postoperative; Pyrroles; Tolmetin; Tooth Extraction	1983
Mild analgesics and the accident and emergency department--cost and safety more important than potency? Archives of emergency medicine, 1984, Volume: 1, Issue:4 Topics: Acetaminophen; Analgesics; Clinical Trials as Topic; Costs and Cost Analysis; Emergencies; Emergency Service, Hospital; England; Fenoprofen; Humans; Mefenamic Acid; Prospective Studies; Tolmetin	1984

Other Studies

11 other study(ies) available for mefenamic acid and zomepirac

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney	2011
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach. European journal of medicinal chemistry, 2012, Volume: 53 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Designing around Structural Alerts in Drug Discovery. Journal of medicinal chemistry, 2020, 06-25, Volume: 63, Issue:12 Topics: Drug Design; Drug Development; Drug Discovery; Drug-Related Side Effects and Adverse Reactions; Humans; Molecular Structure; Pharmaceutical Preparations; Structure-Activity Relationship	2020
Poisoning after overdose with non-steroidal anti-inflammatory drugs. Adverse drug reactions and acute poisoning reviews, 1984,Spring, Volume: 3, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Child, Preschool; Diflunisal; Female; Fenoprofen; Feprazone; Humans; Ibuprofen; Indomethacin; Ketoprofen; London; Male; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Tolmetin	1984
[Treatment of postoperative pain. Zomepirac, mefenamic acid and placebo]. MMW, Munchener medizinische Wochenschrift, 1982, Oct-08, Volume: 124, Issue:40 Topics: Adult; Analgesics; Double-Blind Method; Humans; Mefenamic Acid; Pain, Postoperative; Pyrroles; Random Allocation; Tolmetin	1982
Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy. Chemical research in toxicology, 2007, Volume: 20, Issue:6 Topics: Acylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Chromatography, Liquid; Cyclooxygenase Inhibitors; Diclofenac; Drug Stability; Flufenamic Acid; Glucuronides; Half-Life; Ibuprofen; Indomethacin; Kinetics; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mefenamic Acid; Molecular Structure; Rats; Rats, Sprague-Dawley; Stereoisomerism; Technology, Pharmaceutical; Tolmetin	2007
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3. PloS one, 2012, Volume: 7, Issue:8 Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Flufenamic Acid; Flurbiprofen; Hydroxyprostaglandin Dehydrogenases; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Naproxen; Sulindac; Tolmetin	2012