mefenamic acid and sulindac

mefenamic acid has been researched along with sulindac in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (30.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (20.00)	29.6817
2010's	10 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Gozalbes, R; Pineda-Lucena, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T	1
Kumar, M; Sinha, VR; Thareja, S	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Buchanan, WW; El-Ghobarey, AF; Macleod, MM; Stephens, WH	1
Evens, RP	1
Penning, TM; Smithgall, TE	1
Melvin, JR; Osyamkpe, CO; Sanfilippo, JS; Teichman, J; Wittliff, JL	1
Grimshaw, JJ; Jaffe, GV; Owen-Reece, AR	1
Mills, JA; Simon, LS	1
Amberger, A; Dietl, P; Margreiter, R; Ofner, D; Weiss, H; Widschwendter, M	1
Chen, YJ; Lin, CC; Lin, PC; Su, AK; Tseng, MC	1
Au, AL; Chan, SW; Kwan, YW; Lee, SM; Leung, GP; Li, RW; Seto, SW; Tse, CM	1
Chai, MZ; Flanagan, JU; Squire, CJ; Teague, RM; Turnbull, AP; Yosaatmadja, Y	1

Reviews

3 review(s) available for mefenamic acid and sulindac

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug therapy reviews: antirheumatic agents. American journal of hospital pharmacy, 1979, Volume: 36, Issue:5 Topics: Anti-Inflammatory Agents; Antimalarials; Glucocorticoids; Gold; Humans; Immunosuppressive Agents; Indomethacin; Mefenamic Acid; Penicillamine; Phenylbutazone; Phenylpropionates; Rheumatic Diseases; Salicylates; Sulindac; Tolmetin	1979
Nonsteroidal antiinflammatory drugs (second of two parts). The New England journal of medicine, 1980, May-29, Volume: 302, Issue:22 Topics: Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Fenoprofen; Humans; Ibuprofen; Mefenamic Acid; Naproxen; Propionates; Sulindac; Tolmetin	1980

Trials

2 trial(s) available for mefenamic acid and sulindac

Article	Year
A double-blind, crossover trial of mefenamic acid, sulindac and flurbiprofen in rheumatoid arthritis. Current medical research and opinion, 1979, Volume: 5, Issue:10 Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Flurbiprofen; Humans; Indenes; Male; Mefenamic Acid; Middle Aged; Propionates; Sulindac	1979
A controlled study of mefenamic acid and sulindac in osteoarthrosis. The British journal of clinical practice, 1982, Volume: 36, Issue:2 Topics: Aged; Bone Diseases; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Indenes; Joint Diseases; Male; Mefenamic Acid; Sulindac	1982

Other Studies

15 other study(ies) available for mefenamic acid and sulindac

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney	2011
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach. European journal of medicinal chemistry, 2012, Volume: 53 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Inhibition of trans-dihydrodiol oxidation by the non-steroidal anti-inflammatory drugs. Carcinogenesis, 1986, Volume: 7, Issue:4 Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Anti-Inflammatory Agents; Aspirin; Benzopyrenes; Dihydroxydihydrobenzopyrenes; Flufenamic Acid; Ibuprofen; Indomethacin; Liver; Male; Meclofenamic Acid; Mefenamic Acid; Oxidoreductases; Rats; Sulindac; Tolmetin	1986
Influence of certain prostaglandin synthetase inhibitors on cytoplasmic estrogen receptors in the uterus. American journal of obstetrics and gynecology, 1983, Jan-01, Volume: 145, Issue:1 Topics: Animals; Binding Sites; Cyclooxygenase Inhibitors; Cytoplasm; Female; Ibuprofen; Indomethacin; Mefenamic Acid; Rats; Rats, Inbred Strains; Receptors, Estrogen; Sulindac; Time Factors; Uterus	1983
Inhibition of store-operated calcium entry contributes to the anti-proliferative effect of non-steroidal anti-inflammatory drugs in human colon cancer cells. International journal of cancer, 2001, Jun-15, Volume: 92, Issue:6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Calcium; Cell Cycle; Cell Division; Cell Separation; Colonic Neoplasms; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Flow Cytometry; Humans; Inhibitory Concentration 50; Lanthanum; Lipid Metabolism; Mefenamic Acid; Pyridines; Sulindac; Thapsigargin; Time Factors; Triazoles; Tumor Cells, Cultured	2001
Functionalized magnetic nanoparticles for small-molecule isolation, identification, and quantification. Analytical chemistry, 2007, May-01, Volume: 79, Issue:9 Topics: Flufenamic Acid; Humans; Ketoprofen; Macrolides; Magnetics; Mannose; Mefenamic Acid; Molecular Structure; Nanoparticles; Particle Size; Prednisolone; Robotics; Salicylamides; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulindac	2007
Inhibitory effect of nonsteroidal anti-inflammatory drugs on adenosine transport in vascular smooth muscle cells. European journal of pharmacology, 2009, Jun-10, Volume: 612, Issue:1-3 Topics: Adenosine; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Cell Proliferation; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Etodolac; Humans; Indomethacin; Inhibitory Concentration 50; Ketoprofen; Kinetics; Mefenamic Acid; Muscle, Smooth, Vascular; Piroxicam; Sulindac; Temperature; Tetrazolium Salts; Thiazoles; Thioinosine	2009
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3. PloS one, 2012, Volume: 7, Issue:8 Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Flufenamic Acid; Flurbiprofen; Hydroxyprostaglandin Dehydrogenases; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Naproxen; Sulindac; Tolmetin	2012