mefenamic acid and morphine

mefenamic acid has been researched along with morphine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19905 (33.33)18.7374
1990's3 (20.00)18.2507
2000's3 (20.00)29.6817
2010's4 (26.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chang, TK; Ensom, MH; Kiang, TK1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bhattacharya, SK; Parmar, SS1
Guivernau, M; Muñoz, C; Paeile, C1
Contreras, E; Pincheira, Y; Quijada, L; Tamayo, L1
Hirose, K; Jyoyama, H1
Breeson, AJ; Ezeh, UO; Lamb, MD; Martin, JL; Shoulder, VS; Vellacott, ID1
Adachi, K1
Joshi, GP; Kenny, P; McCarroll, SM; McSwiney, MM1
FLATAKER, L; WINTER, CA1
Kamimura, H; Mano, Y; Usui, T2

Reviews

2 review(s) available for mefenamic acid and morphine

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for mefenamic acid and morphine

ArticleYear
Local anaesthetic on Filshie clips for pain relief after tubal sterilisation: a randomised double-blind controlled trial.
    Lancet (London, England), 1995, Jul-08, Volume: 346, Issue:8967

    Topics: Adult; Cyclizine; Diclofenac; Double-Blind Method; Female; Gels; Humans; Laparoscopy; Lidocaine; Mefenamic Acid; Morphine; Nausea; Pain Measurement; Pain, Postoperative; Patient Discharge; Pelvic Pain; Placebos; Sterilization, Tubal; Surface Properties; Vomiting

1995
Analgesia following arthroscopic knee surgery. A controlled study of intra-articular morphine, bupivacaine or both combined.
    Anaesthesia and intensive care, 1993, Volume: 21, Issue:2

    Topics: Adult; Analgesia; Arthroscopy; Bupivacaine; Cartilage, Articular; Double-Blind Method; Drug Combinations; Female; Humans; Injections, Intra-Articular; Knee Joint; Male; Mefenamic Acid; Meperidine; Morphine; Pain Measurement; Pain, Postoperative

1993

Other Studies

11 other study(ies) available for mefenamic acid and morphine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Stress by restraining potentiates morphine catalepsy in rats.
    Experientia, 1985, Dec-15, Volume: 41, Issue:12

    Topics: 5,6-Dihydroxytryptamine; Animals; Benserazide; Catalepsy; Diclofenac; Ditiocarb; Drug Interactions; Fenclonine; Hemicholinium 3; Levodopa; Male; Mefenamic Acid; Morphine; Naloxone; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Physiological

1985
Influence of anti-inflammatory drugs on the electroencephalographic effect of morphine in rabbits.
    Pharmacology, 1974, Volume: 11, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antipyrine; Electroencephalography; Indomethacin; Male; Mefenamic Acid; Mesylates; Morphine; Rabbits; Salicylates; Stimulation, Chemical

1974
Relationship between adrenergic mechanisms and the analgesic effect of sodium salicylate and mefenamic acid.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 179, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Dibenzylchlorethamine; Electric Stimulation; Guanethidine; Mefenamic Acid; Morphine; Nialamide; ortho-Aminobenzoates; Phenoxybenzamine; Rats; Reserpine; Sodium Salicylate; Sympathomimetics; Tolazoline

1969
Measurement of arthritic pain and effects of analgesics in the adjuvant-treated rat.
    Japanese journal of pharmacology, 1971, Volume: 21, Issue:6

    Topics: Adjuvants, Immunologic; Aminopyrine; Analgesics; Animals; Arthritis; Aspirin; Female; Hydrocortisone; Indomethacin; Mefenamic Acid; Morphine; Pain; Phenylbutazone; Pyrazoles; Rats; Salicylamides

1971
A device for automatic measurement of writhing and its application to the assessment of analgesic agents.
    Journal of pharmacological and toxicological methods, 1994, Volume: 32, Issue:2

    Topics: Acetates; Acetic Acid; Aminopyrine; Analgesics; Animals; Behavior, Animal; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Electric Stimulation; Inflammation; Injections, Subcutaneous; Male; Mefenamic Acid; Mice; Morphine; Pain; Pain Measurement; Time Factors; Transducers

1994
NOCICEPTIVE THRESHOLDS AS AFFECTED BY PARENTERAL ADMINISTRATION OF IRRITANTS AND OF VARIOUS ANTINOCICEPTIVE DRUGS.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 148

    Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Flufenamic Acid; Indoles; Indomethacin; Injections, Intraperitoneal; Irritants; Mefenamic Acid; Morphine; Pain; Pharmaceutical Preparations; Pharmacology; Phenacetin; Quinones; Rats; Research; Stearic Acids

1965
Predominant contribution of UDP-glucuronosyltransferase 2B7 in the glucuronidation of racemic flurbiprofen in the human liver.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dideoxynucleosides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flurbiprofen; Glucuronides; Glucuronosyltransferase; Humans; Kinetics; Liver; Mefenamic Acid; Metabolic Detoxication, Phase II; Microsomes, Liver; Morphine; Morphine Derivatives; Recombinant Proteins; Stereoisomerism; UDP-Glucuronosyltransferase 1A9; Zidovudine

2007
The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:11

    Topics: Catalysis; Enzyme Inhibitors; Estradiol; Flurbiprofen; Gemfibrozil; Glucuronosyltransferase; Glycosylation; Humans; Hypolipidemic Agents; Isoenzymes; Kinetics; Mefenamic Acid; Microsomes, Liver; Molecular Structure; Morphine; Propofol; Recombinant Proteins

2007