mefenamic acid and ketoprofen

mefenamic acid has been researched along with ketoprofen in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19907 (23.33)18.7374
1990's1 (3.33)18.2507
2000's8 (26.67)29.6817
2010's13 (43.33)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Chang, TK; Ensom, MH; Kiang, TK1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Ekins, S; Williams, AJ; Xu, JJ1
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T1
Kumar, M; Sinha, VR; Thareja, S1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Bellman, K; Knegtel, RM; Settimo, L1
Kourounakis, PN; Kourti, M; Rekka, EA; Theodosis-Nobelos, P; Tziona, P1
Gavalas, A; Kourti, M; Rekka, EA; Theodosis-Nobelos, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Anderson, JA; Buchanan, WW; Lee, P; Miller, J; Webb, J1
Huskisson, EC1
Hart, FD1
Reinicke, C1
Cheymol, G; Lebot, M; Poirier, JM1
Ito, M; Miura, Y; Muroi, K; Sakamoto, S; Sasaki, R; Suda, T1
Bourgouin, J; Hébert, JG; Le Morvan, P1
Court, H; Volans, GN1
Lozano, JJ; Pouplana, R; Ruiz, J1
De Alencastro, LF; Grandjean, D; Tarradellas, J; Tauxe-Wuersch, A1
Chen, YJ; Lin, CC; Lin, PC; Su, AK; Tseng, MC1
Hung, CY; Hwang, CC1
Au, AL; Chan, SW; Kwan, YW; Lee, SM; Leung, GP; Li, RW; Seto, SW; Tse, CM1
Eguchi, S; Hasegawa, S; Nakano, E; Okada, K; Sunagawa, A; Tanaka, M; Yamamoto, F; Yamamoto, R; Yokota, H1
Fukushima, T; Hara-Yamamura, H; Nakashima, K; Okabe, S1

Reviews

4 review(s) available for mefenamic acid and ketoprofen

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antiinflammatory drugs.
    Seminars in arthritis and rheumatism, 1977, Volume: 7, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Benzylidene Compounds; Child; Drug Evaluation; Female; Humans; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Mefenamic Acid; Naproxen; Phenylacetates; Phenylbutazone; Pregnancy; Pregnancy Complications; Propionates; Tolmetin

1977
[Nonsteroid antirheumatic agents].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1977, Jul-15, Volume: 32, Issue:14

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Fenoprofen; Flufenamic Acid; Humans; Indomethacin; Ketoprofen; Mefenamic Acid; Naproxen; Phenylbutazone; Propionates; Salicylates

1977

Trials

2 trial(s) available for mefenamic acid and ketoprofen

ArticleYear
Evaluation of analgesic action and efficacy of antirheumatic drugs. Study of 10 drugs in 684 patients with rheumatoid arthritis.
    The Journal of rheumatology, 1976, Volume: 3, Issue:3

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Mefenamic Acid; Pain; Phenylacetates; Placebos; Prednisone; Salicylates

1976
Double-blind comparison of ketoprofen and mefenamic acid in the treatment of primary dysmenorrhea.
    Clinical therapeutics, 1986, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Humans; Ketoprofen; Mefenamic Acid; Middle Aged; Pain; Phenylpropionates; Time Factors

1986

Other Studies

24 other study(ies) available for mefenamic acid and ketoprofen

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney

2011
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
    European journal of medicinal chemistry, 2012, Volume: 53

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.
    Bioorganic & medicinal chemistry letters, 2015, Nov-15, Volume: 25, Issue:22

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cinnamates; Edema; Esters; Glycine max; Hyperlipidemias; Indoleacetic Acids; Lipoxygenase Inhibitors; Polyethylene Glycols; Propanols; Propionates; Rats; Thioctic Acid

2015
Amides of non-steroidal anti-inflammatory drugs with thiomorpholine can yield hypolipidemic agents with improved anti-inflammatory activity.
    Bioorganic & medicinal chemistry letters, 2016, Feb-01, Volume: 26, Issue:3

    Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholesterol; Cholesterol, LDL; Edema; Hyperlipidemias; Hypolipidemic Agents; Morpholines; Rats; Triglycerides

2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
The new antirheumatic drugs.
    Drugs, 1975, Volume: 9, Issue:5

    Topics: Anti-Inflammatory Agents; Fenoprofen; Flufenamic Acid; Humans; Ibuprofen; Ketoprofen; Mefenamic Acid; Naproxen; Penicillamine; Phenylacetates; Rheumatic Diseases; Salicylates

1975
Rapid and sensitive liquid chromatographic assay of mefenamic acid in plasma.
    Therapeutic drug monitoring, 1992, Volume: 14, Issue:4

    Topics: Carbamazepine; Chromatography, Liquid; Clonazepam; Humans; Hydrogen-Ion Concentration; Indomethacin; Ketoprofen; Least-Squares Analysis; Mefenamic Acid; Phenobarbital; Phenytoin; Salicylates; Salicylic Acid; Sensitivity and Specificity; Valproic Acid

1992
Treatment of drug-induced agranulocytosis with granulocyte-colony stimulating factor.
    Lancet (London, England), 1989, Jul-01, Volume: 2, Issue:8653

    Topics: Agranulocytosis; Colony-Stimulating Factors; Granulocyte Colony-Stimulating Factor; Humans; Ketoprofen; Male; Mefenamic Acid; Middle Aged; Recombinant Proteins

1989
Poisoning after overdose with non-steroidal anti-inflammatory drugs.
    Adverse drug reactions and acute poisoning reviews, 1984,Spring, Volume: 3, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Child, Preschool; Diflunisal; Female; Fenoprofen; Feprazone; Humans; Ibuprofen; Indomethacin; Ketoprofen; London; Male; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Tolmetin

1984
Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2).
    Journal of molecular graphics & modelling, 2002, Volume: 20, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Computer Graphics; Computer Simulation; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Energy Transfer; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Ketoprofen; Meclofenamic Acid; Mefenamic Acid; Membrane Proteins; Models, Molecular; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides

2002
Occurrence of several acidic drugs in sewage treatment plants in Switzerland and risk assessment.
    Water research, 2005, Volume: 39, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Clofibric Acid; Diclofenac; Environmental Monitoring; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Mefenamic Acid; No-Observed-Adverse-Effect Level; Risk Assessment; Sewage; Switzerland; Waste Disposal, Fluid; Water Pollutants, Chemical

2005
Functionalized magnetic nanoparticles for small-molecule isolation, identification, and quantification.
    Analytical chemistry, 2007, May-01, Volume: 79, Issue:9

    Topics: Flufenamic Acid; Humans; Ketoprofen; Macrolides; Magnetics; Mannose; Mefenamic Acid; Molecular Structure; Nanoparticles; Particle Size; Prednisolone; Robotics; Salicylamides; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulindac

2007
Analysis of ketoprofen and mefenamic acid by high-performance liquid chromatography with molecularly imprinted polymer as the stationary phase.
    Journal of chromatographic science, 2008, Volume: 46, Issue:9

    Topics: Chromatography, High Pressure Liquid; Ketoprofen; Mefenamic Acid; Molecular Imprinting; Uncertainty

2008
Inhibitory effect of nonsteroidal anti-inflammatory drugs on adenosine transport in vascular smooth muscle cells.
    European journal of pharmacology, 2009, Jun-10, Volume: 612, Issue:1-3

    Topics: Adenosine; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Cell Proliferation; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Etodolac; Humans; Indomethacin; Inhibitory Concentration 50; Ketoprofen; Kinetics; Mefenamic Acid; Muscle, Smooth, Vascular; Piroxicam; Sulindac; Temperature; Tetrazolium Salts; Thiazoles; Thioinosine

2009
Assessment of in vitro antiovulatory activities of nonsteroidal anti-inflammatory drugs and comparison with in vivo reproductive toxicities of medaka (Oryzias latipes).
    Environmental toxicology, 2016, Volume: 31, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Female; Humans; Ketoprofen; Mefenamic Acid; Oryzias; Ovary; Ovulation; Ovum; Reproduction; Salicylic Acid; Water Pollutants, Chemical

2016
Transcriptomic response of HepG2 cells exposed to three common anti-inflammatory drugs: Ketoprofen, mefenamic acid, and diclofenac in domestic wastewater effluents.
    Chemosphere, 2022, Volume: 286, Issue:Pt 2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Hep G2 Cells; Humans; Ketoprofen; Mefenamic Acid; Pharmaceutical Preparations; Transcriptome; Wastewater; Water Pollutants, Chemical

2022