mefenamic acid and furosemide

mefenamic acid has been researched along with furosemide in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.54)18.7374
1990's4 (15.38)18.2507
2000's7 (26.92)29.6817
2010's12 (46.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK1
Chang, TK; Ensom, MH; Kiang, TK1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Ekins, S; Williams, AJ; Xu, JJ1
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Barlow, JW; Lim, CF; Raggatt, LE; Stockigt, JR; Topliss, DJ1
Barlow, JW; Curtis, AJ; Lim, CF; Stockigt, JR; Topliss, DJ1
Benvenga, S; Cahnmann, HJ; Gregg, RE; Robbins, J1
Benvenga, S; Li Calzi, L; Robbins, J1
Hamblin, PS; Kolliniatis, E; Lim, CF; Stockigt, JR; Topliss, DJ1
Benvenga, S; Cahnmann, HJ; Robbins, J1
Andrikopoulou, DA; Glynou, KM; Ioannou, PC; Rusakova, NV; Tzompanaki, GM1
Khazine, F; Simons, O1
Katz, U; Nagel, W; Somieski, P1
Karami-Tehrani, F; Mokarram, P; Salami, S1
Hosseini-Baharanchi, FS; Rafieian-Kopaei, M; Raisi Dehkordi, Z1

Reviews

2 review(s) available for mefenamic acid and furosemide

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for mefenamic acid and furosemide

ArticleYear
A double-blind controlled crossover study to investigate the efficacy of salix extract on primary dysmenorrhea.
    Complementary therapies in medicine, 2019, Volume: 44

    Topics: Adult; Cross-Over Studies; Double-Blind Method; Dysmenorrhea; Female; Humans; Mefenamic Acid; Plant Extracts; Quality of Life; Salix; Young Adult

2019

Other Studies

23 other study(ies) available for mefenamic acid and furosemide

ArticleYear
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
Characterization of cytoplasmic T3 binding sites by adsorption to hydroxyapatite: effects of drug inhibitors of T3 and relationship to glutathione-S-transferases.
    Thyroid : official journal of the American Thyroid Association, 1992,Spring, Volume: 2, Issue:1

    Topics: Amiodarone; Animals; Binding Sites; Binding, Competitive; Cytosol; Diclofenac; Dithiothreitol; Dose-Response Relationship, Drug; Durapatite; Furosemide; Glutathione Transferase; Hydrocortisone; Hydroxyapatites; In Vitro Techniques; Iopanoic Acid; Liver; Macaca fascicularis; Mefenamic Acid; Sulfobromophthalein; Taurocholic Acid; Triiodothyronine

1992
Interactions between oleic acid and drug competitors influence specific binding of thyroxine in serum.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 73, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding, Competitive; Diflunisal; Furosemide; Humans; Kinetics; Meclofenamic Acid; Mefenamic Acid; Oleic Acid; Oleic Acids; Phenylacetates; Thyroxine; Thyroxine-Binding Proteins

1991
Characterization of the binding of thyroxine to high density lipoproteins and apolipoproteins A-I.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 68, Issue:6

    Topics: Apolipoprotein A-I; Apolipoproteins A; Autoradiography; Binding Sites; Diclofenac; Furosemide; Lipoproteins, HDL; Lipoproteins, VLDL; Mefenamic Acid; Temperature; Thyroid Hormones; Thyroxine; Thyroxine-Binding Proteins; Time Factors

1989
Effect of free fatty acids and nonlipid inhibitors of thyroid hormone binding in the immunoradiometric assay of thyroxin-binding globulin.
    Clinical chemistry, 1987, Volume: 33, Issue:10

    Topics: Binding, Competitive; Diclofenac; False Negative Reactions; Fatty Acids, Nonesterified; Furosemide; Humans; Mefenamic Acid; Phenylacetates; Radioimmunoassay; Reagent Kits, Diagnostic; Thyroxine; Thyroxine-Binding Proteins

1987
Furosemide, fenclofenac, diclofenac, mefenamic acid and meclofenamic acid inhibit specific T3 binding in isolated rat hepatic nuclei.
    Journal of endocrinological investigation, 1988, Volume: 11, Issue:5

    Topics: Amiodarone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Nucleus; Diclofenac; Furosemide; In Vitro Techniques; Liver; Male; Meclofenamic Acid; Mefenamic Acid; Phenylacetates; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Thyroid Hormone

1988
Characterization of thyroid hormone binding to apolipoprotein-E: localization of the binding site in the exon 3-coded domain.
    Endocrinology, 1993, Volume: 133, Issue:3

    Topics: Affinity Labels; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Apolipoproteins E; Binding Sites; Blood Proteins; Diclofenac; Exons; Furosemide; Isoelectric Focusing; Mefenamic Acid; Mice; Molecular Sequence Data; Mutation; Photochemistry; Thyroxine

1993
Spectrofluorimetric determination of anthranilic acid derivatives based on terbium sensitized fluorescence.
    The Analyst, 1998, Volume: 123, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diuretics; Furosemide; Humans; Mefenamic Acid; ortho-Aminobenzoates; Spectrometry, Fluorescence; Terbium

1998
[A possible adverse effect from the association of losartan-mefenamic acid in hemodialysis].
    Nephrologie, 2001, Volume: 22, Issue:2

    Topics: Adult; Antihypertensive Agents; Atenolol; Cyclooxygenase Inhibitors; Drug Interactions; Drug Therapy, Combination; Female; Furosemide; Glomerulonephritis, IGA; Humans; Hypertension; Losartan; Mefenamic Acid; Renal Dialysis

2001
Selective inhibition of Cl(-) conductance in toad skin by blockers of Cl(-) channels and transporters.
    American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Bufonidae; Bumetanide; Calcium Channel Blockers; Carrier Proteins; Chloride Channels; Chlorides; Cyclooxygenase Inhibitors; Diuretics; Dose-Response Relationship, Drug; Electric Conductivity; Eosine Yellowish-(YS); Flufenamic Acid; Fluorescent Dyes; Furosemide; Mefenamic Acid; Membrane Potentials; Niflumic Acid; Nitrobenzoates; ortho-Aminobenzoates; Patch-Clamp Techniques; Skin

2001
Competition of tamoxifen with thyroxine for TBG binding: ligand binding assay and computational data.
    Clinical biochemistry, 2001, Volume: 34, Issue:8

    Topics: Binding, Competitive; Diclofenac; Furosemide; Humans; Mefenamic Acid; Models, Molecular; Molecular Conformation; Tamoxifen; Thyroxine; Thyroxine-Binding Proteins

2001