mefenamic acid has been researched along with flurbiprofen in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (19.05) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 11 (52.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T | 1 |
| Choi, S; Kelly, JW | 1 |
| Kumar, M; Sinha, VR; Thareja, S | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Anderson, JA; Buchanan, WW; Lee, P; Miller, J; Webb, J | 2 |
| Buchanan, WW; El-Ghobarey, AF; Macleod, MM; Stephens, WH | 1 |
| Lands, WE; Rome, LH | 1 |
| Lozano, JJ; Pouplana, R; Ruiz, J | 1 |
| Kamimura, H; Mano, Y; Usui, T | 2 |
| Chai, MZ; Flanagan, JU; Squire, CJ; Teague, RM; Turnbull, AP; Yosaatmadja, Y | 1 |
2 review(s) available for mefenamic acid and flurbiprofen
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 trial(s) available for mefenamic acid and flurbiprofen
| Article | Year |
|---|---|
Evaluation of analgesic action and efficacy of antirheumatic drugs. Study of 10 drugs in 684 patients with rheumatoid arthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Mefenamic Acid; Pain; Phenylacetates; Placebos; Prednisone; Salicylates | 1976 |
A double-blind, crossover trial of mefenamic acid, sulindac and flurbiprofen in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Flurbiprofen; Humans; Indenes; Male; Mefenamic Acid; Middle Aged; Propionates; Sulindac | 1979 |
[Comparative evaluation of the therapeutic efficiency of flurbiprofene in rheumatoid polyarthritis].
Topics: Acetaminophen; Arthritis, Rheumatoid; Aspirin; Biphenyl Compounds; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Fluorobenzenes; Flurbiprofen; Humans; Indomethacin; Mefenamic Acid; Pain; Phenylpropionates; Placebos; Prednisone; Propionates | 1975 |
16 other study(ies) available for mefenamic acid and flurbiprofen
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney | 2011 |
A competition assay to identify amyloidogenesis inhibitors by monitoring the fluorescence emitted by the covalent attachment of a stilbene derivative to transthyretin.
Topics: Amyloid; Humans; Kinetics; Models, Molecular; Prealbumin; Protein Interaction Domains and Motifs; Protein Structure, Quaternary; Spectrometry, Fluorescence; Stilbenes | 2011 |
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Structural requirements for time-dependent inhibition of prostaglandin biosynthesis by anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Fatty Acids; Flurbiprofen; Ibuprofen; Indomethacin; Kinetics; Meclofenamic Acid; Mefenamic Acid; Oxygen Consumption; Oxygenases; Prostaglandins; Structure-Activity Relationship | 1975 |
Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Computer Graphics; Computer Simulation; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Energy Transfer; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Ketoprofen; Meclofenamic Acid; Mefenamic Acid; Membrane Proteins; Models, Molecular; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides | 2002 |
Predominant contribution of UDP-glucuronosyltransferase 2B7 in the glucuronidation of racemic flurbiprofen in the human liver.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dideoxynucleosides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flurbiprofen; Glucuronides; Glucuronosyltransferase; Humans; Kinetics; Liver; Mefenamic Acid; Metabolic Detoxication, Phase II; Microsomes, Liver; Morphine; Morphine Derivatives; Recombinant Proteins; Stereoisomerism; UDP-Glucuronosyltransferase 1A9; Zidovudine | 2007 |
The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver.
Topics: Catalysis; Enzyme Inhibitors; Estradiol; Flurbiprofen; Gemfibrozil; Glucuronosyltransferase; Glycosylation; Humans; Hypolipidemic Agents; Isoenzymes; Kinetics; Mefenamic Acid; Microsomes, Liver; Molecular Structure; Morphine; Propofol; Recombinant Proteins | 2007 |
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Flufenamic Acid; Flurbiprofen; Hydroxyprostaglandin Dehydrogenases; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Naproxen; Sulindac; Tolmetin | 2012 |