Compounds > mefenamic acid

mefenamic acid and 1-o-(2-(2,3-dimethylphenyl)aminobenzoyl)glucopyranuronic acid

mefenamic acid has been researched along with 1-o-(2-(2,3-dimethylphenyl)aminobenzoyl)glucopyranuronic acid in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grillo, MP; Tadano Lohr, M; Wait, JC1
Bando, H; Ito, K; Sato, J; Yamane, Y1
Burchell, B; Hosagrahara, VP; McGurk, KA; Remmel, RP; Tosh, D1
Obach, RS1
Benet, LZ; Horng, H1
Fong, SY; Han, Q; Wong, YC; Zhang, Y; Zhou, L; Zuo, Z1

Other Studies

6 other study(ies) available for mefenamic acid and 1-o-(2-(2,3-dimethylphenyl)aminobenzoyl)glucopyranuronic acid

ArticleYear
Metabolic activation of mefenamic acid leading to mefenamyl-S-acyl-glutathione adduct formation in vitro and in vivo in rat.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:8

    Topics: Animals; Biotransformation; Chromatography, Liquid; Glutathione; Hepatocytes; Humans; In Vitro Techniques; Mefenamic Acid; Rats; Tandem Mass Spectrometry

2012
Structures of mefenamic acid metabolites from human urine.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:8

    Topics: Adult; Biotransformation; Glucuronates; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Male; Mefenamic Acid

1993
Reactivity of mefenamic acid 1-o-acyl glucuronide with proteins in vitro and ex vivo.
    Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cricetinae; Cricetulus; Glucuronates; Half-Life; Humans; Magnetic Resonance Spectroscopy; Mefenamic Acid; Protein Binding

1996
Glycerolysis of acyl glucuronides as an artifact of in vitro drug metabolism incubations.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Artifacts; Biological Assay; Biotransformation; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Diclofenac; Glucuronates; Glucuronides; Glycerol; Humans; In Vitro Techniques; Mass Spectrometry; Mefenamic Acid; Microsomes, Liver; Naproxen; Propionates; Tolmetin; Uridine Diphosphate Glucuronic Acid

2009
The nonenzymatic reactivity of the acyl-linked metabolites of mefenamic acid toward amino and thiol functional group bionucleophiles.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:11

    Topics: Acetylcysteine; Acyl Coenzyme A; Acylation; Adenosine Monophosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Glucuronates; Glutathione; Male; Mefenamic Acid; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds

2013
Identification and disposition of novel mono-hydroxyl mefenamic acid and their potentially toxic 1-O-acyl-glucuronides in vivo.
    Biopharmaceutics & drug disposition, 2015, Volume: 36, Issue:8

    Topics: Administration, Oral; Animals; Biotransformation; Brain; Chromatography, Liquid; Dose-Response Relationship, Drug; Glucuronates; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Male; Mefenamic Acid; Microsomes, Liver; Molecular Structure; Perfusion; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tissue Distribution

2015