medetomidine has been researched along with prazosin in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.35) | 18.7374 |
| 1990's | 18 (78.26) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 3 (13.04) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Saeki, S; Yaksh, TL | 1 |
| Baden, JM; Fujinaga, M; Hoffman, BB; Maze, M | 1 |
| Correa-Sales, C; Maze, M; Rabin, BC | 1 |
| Bloor, BC; Blow, KD; Flacke, JW; Flacke, WE; McIntee, DF | 1 |
| Sperlágh, B; Vizi, ES | 1 |
| Guo, TZ; Maze, M; Oliker, R; Tinklenberg, J | 1 |
| Amemiya, Y; Fashempour, J; Feller, DR; Hamada, A; Hsu, F; Miller, DD; Romstedt, KJ; Shams, G; Tantishaiyakul, V; Venkataraman, BV | 1 |
| Nyman, L; Saano, V; Savola, JM; Virtanen, R | 1 |
| Chen, TH; Hsu, WH | 1 |
| Day, TK; Muir, WW | 1 |
| Chen, MJ; Chiu, TH; Tang, FI; Yang, JJ; Yang, YR | 1 |
| Barsh, GS; Bernstein, D; Chruscinski, A; Desai, K; Hein, L; Kobilka, BK; Link, RE; Stevens, ME | 1 |
| Bryant, CE; Clarke, KW | 1 |
| Blandizzi, C; Carignani, D; Colucci, R; Crema, F; Del Tacca, M; Lazzeri, G; Natale, G | 1 |
| Boulanger, CM; Illiano, S; Marsault, R; Taddei, S; Vanhoutte, PM | 1 |
| Dowlatshahi, P; Yaksh, TL | 1 |
| Haapalinna, A; Heinonen, E; MacDonald, E; Savola, JM; Tuomisto, L; Viitamaa, T; Virtanen, R | 1 |
| Gordon, ES; Koman, LA; Li, Z; Smith, BP; Smith, TL | 1 |
| Audinot, V; Cistarelli, L; Gobert, A; Millan, MJ; Newman-Tancredi, A; Rivet, JM | 1 |
| Bakshi, VP; Carasso, BS; Geyer, MA; Palomo, J; Powell, SB | 1 |
| Hikasa, Y; Miki, Y; Murahata, Y; Yamamoto, A | 1 |
| Asano, K; Egawa, S; Furuta, A; Kimura, S; Suzuki, Y; Yoshimura, N | 1 |
23 other study(ies) available for medetomidine and prazosin
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Suppression by spinal alpha-2 agonists of motor and autonomic responses evoked by low- and high-intensity thermal stimuli.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Heart Rate; Hot Temperature; Imidazoles; Male; Medetomidine; Prazosin; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Adrenergic, alpha; Reflex | 1992 |
Activation of alpha-1 adrenergic receptors modulates the control of left/right sidedness in rat embryos.
Topics: Adrenergic alpha-Agonists; Animals; Dose-Response Relationship, Drug; Embryo, Mammalian; Functional Laterality; Imidazoles; Isomerism; Isoproterenol; Medetomidine; Norepinephrine; Organ Culture Techniques; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1992 |
A hypnotic response to dexmedetomidine, an alpha 2 agonist, is mediated in the locus coeruleus in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Imidazoles; Locus Coeruleus; Male; Medetomidine; Prazosin; Rats; Rats, Inbred Strains | 1992 |
Effect of dexmedetomidine, an alpha 2-adrenergic agonist, in the isolated heart.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atrial Function, Left; Blood Pressure; Cardiac Output; Coronary Circulation; Dogs; Epinephrine; Female; Heart; Heart Rate; Imidazoles; Lung; Male; Medetomidine; Myocardial Contraction; Norepinephrine; Prazosin; Propranolol; Vascular Resistance; Venous Pressure | 1992 |
Is the neuronal ATP release from guinea-pig vas deferens subject to alpha 2-adrenoceptor-mediated modulation?
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Berberine; Clonidine; Electric Stimulation; Guinea Pigs; Imidazoles; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Oxymetazoline; Prazosin; Receptors, Adrenergic, alpha; Reserpine; Vas Deferens; Xylazine; Yohimbine | 1992 |
Central alpha 1-adrenoceptor stimulation functionally antagonizes the hypnotic response to dexmedetomidine, an alpha 2-adrenoceptor agonist.
Topics: Adrenergic alpha-Agonists; Animals; Drug Interactions; Imidazoles; Injections, Intraperitoneal; Injections, Intraventricular; Male; Medetomidine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sleep | 1991 |
Structure-activity studies of new imidazolines on adrenoceptors of rat aorta and human platelets.
Topics: Animals; Aorta, Thoracic; Blood Platelets; Humans; Imidazoles; In Vitro Techniques; Kinetics; Male; Medetomidine; Muscle, Smooth, Vascular; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Structure-Activity Relationship; Sympathomimetics | 1991 |
Characterization of the selectivity, specificity and potency of medetomidine as an alpha 2-adrenoceptor agonist.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Brain; Brimonidine Tartrate; Clonidine; Female; Imidazoles; In Vitro Techniques; Male; Medetomidine; Muscle, Smooth; Mydriatics; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Vas Deferens | 1988 |
Inhibition of insulin release by a formamidine pesticide amitraz and its metabolites in a rat beta-cell line: an action mediated by alpha-2 adrenoceptors, a GTP-binding protein and a decrease in cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Amidines; Animals; Cell Line; Cyclic AMP; GTP-Binding Proteins; Imidazoles; Insecticides; Insulin; Insulin Secretion; Islets of Langerhans; Medetomidine; Prazosin; Rats; Receptors, Adrenergic, alpha-2; Toluidines; Virulence Factors, Bordetella | 1994 |
Alpha 2-adrenergic receptor agonist effects on supraventricular and ventricular automaticity in dogs with complete atrioventricular block.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dog Diseases; Dogs; Formaldehyde; Glycopyrrolate; Heart Block; Heart Rate; Imidazoles; Medetomidine; Prazosin; Ventricular Function; Xylazine | 1993 |
Action of dexmedetomidine on rat locus coeruleus neurones: intracellular recording in vitro.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Barium Compounds; Cesium; Chlorides; Clonidine; Electrophysiology; Imidazoles; In Vitro Techniques; Locus Coeruleus; Male; Medetomidine; Membrane Potentials; Neurons; Oxymetazoline; Parasympathetic Fibers, Postganglionic; Prazosin; Rats; Rats, Sprague-Dawley; Yohimbine | 1995 |
Cardiovascular regulation in mice lacking alpha2-adrenergic receptor subtypes b and c.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Gene Targeting; Heart Rate; Imidazoles; Kidney; Medetomidine; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Muscle, Smooth, Vascular; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-2; Yohimbine | 1996 |
The actions of medetomidine may not be mediated exclusively by alpha 2-adrenoceptors in the equine saphenous vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Brimonidine Tartrate; Dose-Response Relationship, Drug; Electric Stimulation; Endothelium, Vascular; Female; Horses; Imidazoles; Male; Medetomidine; Muscle Contraction; Muscle, Smooth, Vascular; Neuromuscular Junction; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Saphenous Vein; Structure-Activity Relationship | 1996 |
Determination on functional basis of presynaptic alpha 2-adrenoceptor subtypes in guinea-pig duodenum.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cholinergic Fibers; Duodenum; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; Idazoxan; Imidazoles; Indoles; Isoindoles; Isoquinolines; Male; Medetomidine; Muscle Contraction; Nordefrin; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Receptors, Adrenergic, alpha-2; Synaptic Membranes; Vasoconstrictor Agents; Xylazine; Yohimbine | 1996 |
Rilmenidine activates postjunctional alpha 1- and alpha 2-adrenoceptors in the canine saphenous vein.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium Channel Blockers; Clonidine; Dihydropyridines; Dogs; Female; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Isotope Labeling; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Osmolar Concentration; Oxazoles; Phenoxybenzamine; Prazosin; Protein Binding; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Saphenous Vein; Tritium; Yohimbine | 1996 |
Differential effects of two intraventricularly injected alpha 2 agonists, ST-91 and dexmedetomidine, on electroencephalogram, feeding, and electromyogram.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Conscious Sedation; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Feeding Behavior; Imidazoles; Injections, Intraventricular; Male; Medetomidine; Methoxamine; Prazosin; Rats; Rats, Sprague-Dawley; Yohimbine | 1997 |
Evaluation of the effects of a specific alpha 2-adrenoceptor antagonist, atipamezole, on alpha 1- and alpha 2-adrenoceptor subtype binding, brain neurochemistry and behaviour in comparison with yohimbine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Biogenic Amines; Brain; Female; Imidazoles; Male; Medetomidine; Mice; Motor Activity; Prazosin; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Serotonin; Yohimbine | 1997 |
Alpha adrenoceptors in the rabbit ear thermoregulatory microcirculation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Body Temperature Regulation; Ear, External; Imidazoles; Male; Medetomidine; Microcirculation; Models, Cardiovascular; Phenylephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Skin; Vasoconstriction | 1998 |
Simultaneous quantification of serotonin, dopamine and noradrenaline levels in single frontal cortex dialysates of freely-moving rats reveals a complex pattern of reciprocal auto- and heteroreceptor-mediated control of release.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzopyrans; Dopamine; Dopamine Agonists; Frontal Lobe; Guanabenz; Guinea Pigs; Homeostasis; Idazoxan; Imidazoles; Indoles; Isoindoles; Male; Medetomidine; Models, Neurological; Motor Activity; Norepinephrine; Oxadiazoles; Piperazines; Prazosin; Raclopride; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Salicylamides; Serotonin | 1998 |
Yohimbine disrupts prepulse inhibition in rats via action at 5-HT1A receptors, not alpha2-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Guanfacine; Imidazoles; Injections; Male; Medetomidine; Neural Inhibition; Piperazines; Prazosin; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha-2; Reflex, Startle; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Yohimbine | 2005 |
Antagonistic effects of atipamezole, yohimbine and prazosin on medetomidine-induced diuresis in healthy cats.
Topics: Animals; Area Under Curve; Arginine Vasopressin; Cats; Creatinine; Diuresis; Electrolytes; Hydrogen-Ion Concentration; Imidazoles; Medetomidine; Osmolar Concentration; Prazosin; Specific Gravity; Urinalysis; Yohimbine | 2014 |
Noradrenergic Mechanisms Controlling Urethral Smooth and Striated Muscle Function in Urethral Continence Reflex in Rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Neurons; Animals; Benzamidines; Bungarotoxins; Female; Fluoxetine; Medetomidine; Muscle, Smooth; Muscle, Striated; Norepinephrine; Prazosin; Rats; Rats, Sprague-Dawley; Reflex; Urethra | 2015 |