medetomidine has been researched along with morphine in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 20 (57.14) | 18.2507 |
| 2000's | 6 (17.14) | 29.6817 |
| 2010's | 9 (25.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Takano, Y; Yaksh, TL | 1 |
| Bagley, J; Harris, S; Lin, BS; Lloyd, P; Messineo, E; Ossipov, MH | 1 |
| Kalso, EA; Kontinen, VK | 2 |
| Dickenson, AH; Hewett, K; Sullivan, AF | 1 |
| Jorm, CM; Stamford, JA | 1 |
| Dickenson, AH; Stanfa, LC | 1 |
| Kauppila, T; Taira, T; Tanila, H | 1 |
| Dickenson, AH; Kalso, EA; McQuay, HJ; Roques, BP; Sullivan, AF | 1 |
| Puke, MJ; Wiesenfeld-Hallin, Z | 1 |
| Benson, J; Branson, KR; Ko, JC; Thurmon, JC; Tranquilli, WJ | 1 |
| Stevens, CW; Willenbring, S | 1 |
| Besson, JM; Buritova, J; Chapman, V; Honoré, P | 1 |
| Guo, TZ; Hayashi, Y; Maze, M | 1 |
| Idänpään-Heikkilä, JJ; Männistö, PT; Rauhala, P | 1 |
| Asai, T; Mapleson, WW; Power, I | 2 |
| Bieger, D; Loomis, CW; Yao, D | 1 |
| Caldwell, J; Eisenach, JC; Lee, HW; Richardson, CA; Talke, P; Tong, C | 1 |
| Calcutt, NA; Chaplan, SR | 1 |
| Greene, SA; Kalivas, PW; Keegan, RD; Pacharinsak, C | 1 |
| Muir, WW; Wiese, AJ | 1 |
| Augustsson, H; Jensen-Waern, M; Malavasi, LM; Nyman, G | 1 |
| Muir, WW; Ueyama, Y; Ueyema, Y; Waselau, AC; Wiese, AJ | 1 |
| Bersenas, AM; Davis, C; Ethier, MR; Kerr, C; Mathews, KA; Nykamp, SG; Valverde, A | 1 |
| Boure, LP; Desrochers, A; Nykamp, S; Solano, AM; Valverde, A | 1 |
| Galatos, AD; Kazakos, GM; Kostoulas, P; Koutinas, AF; Kritsepi-Konstantinou, M; Mylonakis, ME; Pardali, D; Petanides, T | 1 |
| Del Mar Granados, M; Fernández-Sarmiento, A; Gómez-Villamandos, RJ; López Villalba, I; Manuel Domínguez, J; Morgaz, J; Muñoz-Rascón, P; Navarrete-Calvo, R | 1 |
| Dzikiti, BT; Fosgate, GT; Rioja, E; Stegmann, FG; Venter, FJ; Zeiler, GE | 1 |
| Aarnes, TK; Hildreth, BE; Hubbell, JA | 1 |
| Adams, NJ; Barrett, LA; Beausoleil, NJ; Chambers, JP; Farnworth, MJ; Hekman, M; Stafford, KJ; Thomas, DG; Waran, NK; Weidgraaf, K | 1 |
| Gauthier, O; Holopherne-Doran, D; Michaut-Castrillo, J; Raillard, M; Spreux, D; Touzot-Jourde, G | 1 |
| Lee, DY; Watson, N; Whittem, T | 1 |
| Antończyk, A; Kiełbowicz, Z; Liszka, B; Skrzypczak, P | 1 |
6 trial(s) available for medetomidine and morphine
| Article | Year |
|---|---|
Effect of dexmedetomidine on lumbar cerebrospinal fluid pressure in humans.
Topics: Adjuvants, Anesthesia; Adolescent; Adrenergic alpha-Agonists; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Intravenous; Blood Pressure; Cerebrospinal Fluid Pressure; Double-Blind Method; Female; Heart Rate; Humans; Hypophysectomy; Imidazoles; Infusion Pumps; Infusions, Intravenous; Intracranial Pressure; Male; Medetomidine; Middle Aged; Morphine; Pituitary Neoplasms; Placebos; Sphenoid Bone | 1997 |
Changes in minimal alveolar concentration of isoflurane following treatment with medetomidine and tiletamine/zolazepam, epidural morphine or systemic buprenorphine in pigs.
Topics: Analgesics; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Anxiety Agents; Blood Pressure; Buprenorphine; Drug Interactions; Female; Hypnotics and Sedatives; Isoflurane; Male; Medetomidine; Morphine; Pulmonary Alveoli; Swine; Tiletamine; Zolazepam | 2008 |
Anaesthetic, analgesic and cardiorespiratory effects of intramuscular medetomidine-ketamine combination alone or with morphine or tramadol for orchiectomy in cats.
Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Carbon Dioxide; Cats; Drug Combinations; Drug Therapy, Combination; Injections, Intramuscular; Ketamine; Male; Medetomidine; Morphine; Orchiectomy; Oxygen; Pain; Tramadol; Treatment Outcome | 2014 |
Assessment of a carbon dioxide laser for the measurement of thermal nociceptive thresholds following intramuscular administration of analgesic drugs in pain-free female cats.
Topics: Analgesics; Animals; Buprenorphine; Cats; Female; Hot Temperature; Injections, Intramuscular; Ketoprofen; Lasers, Gas; Medetomidine; Morphine; Pain Threshold; Tramadol | 2015 |
Comparison of medetomidine-morphine and medetomidine-methadone for sedation, isoflurane requirement and postoperative analgesia in dogs undergoing laparoscopy.
Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Combined; Animals; Cross-Over Studies; Dogs; Female; Isoflurane; Laparoscopy; Male; Medetomidine; Methadone; Morphine; Preanesthetic Medication; Propofol | 2017 |
Comparison of analgesia provided by lidocaine or morphine delivered epidurally in rabbits undergoing hindlimb orthopedic surgery.
Topics: Analgesics, Opioid; Anesthesia; Anesthetics, Local; Animals; Blood Pressure; Hindlimb; Injections, Epidural; Ketamine; Lidocaine; Medetomidine; Morphine; Pain, Postoperative; Rabbits | 2019 |
29 other study(ies) available for medetomidine and morphine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Relative efficacy of spinal alpha-2 agonists, dexmedetomidine, clonidine and ST-91, determined in vivo by using N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, an irreversible antagonist.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Imidazoles; Injections, Spinal; Male; Medetomidine; Morphine; Quinolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Spinal Cord | 1991 |
Antinociceptive interaction between opioids and medetomidine: systemic additivity and spinal synergy.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Drug Interactions; Drug Synergism; Fentanyl; Imidazoles; Injections, Intravenous; Injections, Spinal; Male; Medetomidine; Meperidine; Morphine; Pain; Pain Measurement; Rats; Rats, Inbred Strains | 1990 |
Differential modulation of alpha 2-adrenergic and mu-opioid spinal antinociception by neuropeptide FF.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Synergism; Imidazoles; Male; Medetomidine; Morphine; Naltrexone; Narcotic Antagonists; Neuropeptides; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Spinal Cord; Time Factors | 1995 |
Is there any cross-antagonism between mu-opioid and alpha 2-adrenergic receptors in the rat spinal cord?
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Drug Interactions; Imidazoles; Male; Medetomidine; Morphine; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Cord | 1995 |
Differential modulation of alpha 2-adrenergic and opioid spinal antinociception by cholecystokinin and cholecystokinin antagonists in the rat dorsal horn: an electrophysiological study.
Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Anxiety Agents; Benzodiazepinones; Cholecystokinin; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Imidazoles; Indoles; Injections, Spinal; Male; Medetomidine; Meglumine; Morphine; Nerve Fibers; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Cholecystokinin; Receptors, Opioid; Spinal Cord | 1994 |
Actions of morphine on noradrenaline efflux in the rat locus coeruleus are mediated via both opioid and alpha 2 adrenoceptor mechanisms.
Topics: Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Imidazoles; In Vitro Techniques; Locus Coeruleus; Medetomidine; Morphine; Norepinephrine; Rats; Receptors, Adrenergic, alpha-2; Receptors, Opioid | 1995 |
Enhanced alpha-2 adrenergic controls and spinal morphine potency in inflammation.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Carrageenan; Dioxanes; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; Idazoxan; Imidazoles; Inflammation; Injections, Spinal; Male; Medetomidine; Morphine; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2 | 1994 |
Inhibition of intestinal motility and reversal of postlaparotomy ileus by selective alpha 2-adrenergic drugs in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Gastric Emptying; Gastrointestinal Motility; Imidazoles; Intestinal Obstruction; Laparotomy; Male; Medetomidine; Morphine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha | 1993 |
Cross-tolerance between mu opioid and alpha-2 adrenergic receptors, but not between mu and delta opioid receptors in the spinal cord of the rat.
Topics: Adrenergic alpha-Agonists; Amino Acid Sequence; Animals; Behavior, Animal; Drug Tolerance; Evoked Potentials; Imidazoles; Male; Medetomidine; Molecular Sequence Data; Morphine; Neurons; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord | 1993 |
The differential effects of morphine and the alpha 2-adrenoceptor agonists clonidine and dexmedetomidine on the prevention and treatment of experimental neuropathic pain.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Imidazoles; Male; Medetomidine; Morphine; Motor Activity; Pain; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Self Mutilation | 1993 |
Duration of analgesia induced by epidurally administered morphine and medetomidine in dogs.
Topics: Analgesia, Epidural; Analgesics; Animals; Dogs; Drug Combinations; Female; Imidazoles; Injections, Epidural; Medetomidine; Morphine; Motor Activity; Pain; Pain Measurement; Time Factors | 1993 |
Thermal, mechanical and chemical peripheral sensation in amphibians: opioid and adrenergic effects.
Topics: Acetates; Acetic Acid; Adrenergic Agents; Animals; Behavior, Animal; Drug Evaluation, Preclinical; Heating; Imidazoles; Medetomidine; Morphine; Narcotics; Nociceptors; Pain Measurement; Rana pipiens; Sensitivity and Specificity; Sensory Thresholds; Stress, Mechanical | 1996 |
To what extent do spinal interactions between an alpha-2 adrenoceptor agonist and a mu opioid agonist influence noxiously evoked c-Fos expression in the rat? A pharmacological study.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Dose-Response Relationship, Drug; Gene Expression; Imidazoles; Immunohistochemistry; Male; Medetomidine; Morphine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1996 |
Hypnotic and analgesic effects of the alpha 2-adrenergic agonist dexmedetomidine in morphine-tolerant rats.
Topics: Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Animals; Drug Synergism; Drug Tolerance; Hypnotics and Sedatives; Imidazoles; Locus Coeruleus; Male; Medetomidine; Morphine; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Time Factors | 1996 |
Neuroendocrine effects of dexmedetomidine: evidence of cross-tolerance between a mu-opioid agonist and an alpha 2-adrenoceptor agonist in growth hormone secretion of the male rat.
Topics: Adrenergic alpha-Agonists; Animals; Drug Tolerance; Growth Hormone; Imidazoles; Male; Medetomidine; Morphine; Pituitary Hormones, Anterior; Prolactin; Rats; Rats, Wistar; Receptors, Opioid, mu; Thyrotropin | 1996 |
Differential effects of clonidine and dexmedetomidine on gastric emptying and gastrointestinal transit in the rat.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Clonidine; Dose-Response Relationship, Drug; Gastric Emptying; Gastrointestinal Transit; Imidazoles; Male; Medetomidine; Morphine; Naloxone; Rats; Rats, Wistar; Yohimbine | 1997 |
Characterization of an esophagocardiovascular reflex in the rat.
Topics: Adrenergic alpha-Agonists; Animals; Animals, Newborn; Blood Pressure; Capsaicin; Cardiovascular Physiological Phenomena; Cardiovascular System; Catheterization; Esophageal Diseases; Esophagus; Heart Rate; Imidazoles; Injections, Spinal; Male; Medetomidine; Morphine; Narcotics; Paralysis; Rats; Rats, Sprague-Dawley; Reflex; Vagus Nerve | 1997 |
Spinal pharmacology of tactile allodynia in diabetic rats.
Topics: 2-Amino-5-phosphonovalerate; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Imidazoles; Injections, Spinal; Medetomidine; Morphine; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Spinal Cord; Streptozocin | 1997 |
Interactive effect of morphine and dexmedetomidine on gastric emptying and gastrointestinal transit in the rat.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Interactions; Gastric Emptying; Gastrointestinal Transit; Imidazoles; Male; Medetomidine; Morphine; Rats; Rats, Wistar | 1998 |
Postoperative analgesia in dogs receiving epidural morphine plus medetomidine.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Dogs; Female; Heart Rate; Injections, Epidural; Male; Medetomidine; Morphine; Pain Measurement; Pain, Postoperative | 2003 |
Anaesthetic and cardiopulmonary effects of intramuscular morphine, medetomidine and ketamine administered to telemetered cats.
Topics: Analgesics, Opioid; Analysis of Variance; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Cats; Central Nervous System Depressants; Female; Heart Rate; Hypnotics and Sedatives; Injections, Intramuscular; Ketamine; Medetomidine; Morphine; Respiration | 2007 |
Anesthetic and cardiopulmonary effects of intramuscular morphine, medetomidine, ketamine injection in dogs.
Topics: Adrenergic alpha-Antagonists; Analgesia; Anesthesia; Anesthetics; Animals; Dogs; Drug Therapy, Combination; Female; Imidazoles; Ketamine; Male; Medetomidine; Morphine; Time Factors | 2008 |
Evaluation of the efficacy and safety for use of two sedation and analgesia protocols to facilitate assisted ventilation of healthy dogs.
Topics: Analgesics; Analgesics, Opioid; Animals; Blood Pressure; Dogs; Female; Heart Rate; Hydromorphone; Hypnotics and Sedatives; Liquid Ventilation; Male; Medetomidine; Midazolam; Morphine; Reference Values; Safety; Stroke Volume; Treatment Outcome; Vascular Resistance | 2008 |
Behavioural and cardiorespiratory effects of a constant rate infusion of medetomidine and morphine for sedation during standing laparoscopy in horses.
Topics: Analgesics, Opioid; Animals; Blood Gas Analysis; Blood Pressure; Drug Therapy, Combination; Female; Heart Rate; Horses; Hypnotics and Sedatives; Infusions, Intravenous; Laparoscopy; Male; Medetomidine; Morphine; Respiration | 2009 |
Bleeding time in healthy dogs sedated with morphine and medetomidine.
Topics: Animals; Bleeding Time; Conscious Sedation; Dogs; Female; Hypnotics and Sedatives; Male; Medetomidine; Monitoring, Intraoperative; Morphine; Narcotics | 2011 |
Cardiorespiratory, anaesthetic and recovery effects of morphine combined with medetomidine and alfaxalone in rabbits.
Topics: Anesthesia; Anesthesia Recovery Period; Anesthetics, Combined; Animals; Blood Gas Analysis; Blood Pressure; Cross-Over Studies; Female; Injections, Intramuscular; Medetomidine; Morphine; Pregnanediones; Rabbits; Respiration; Respiratory Rate | 2014 |
Use of sedation and ropivacaine-morphine epidural for femoral head and neck ostectomy in a dog.
Topics: Amides; Anesthesia, Epidural; Anesthetics, Combined; Animals; Deep Sedation; Dog Diseases; Dogs; Femur Head; Femur Neck; Ketamine; Lidocaine; Male; Medetomidine; Morphine; Osteotomy; Ropivacaine | 2014 |
Chemical stability of morphine and methadone, and of methadone in combination with acepromazine, medetomidine or xylazine, during prolonged storage in syringes.
Topics: Acepromazine; Animals; Drug Stability; Drug Storage; Medetomidine; Methadone; Morphine; Syringes; Xylazine | 2017 |