Page last updated: 2024-08-24

medetomidine and detomidine

medetomidine has been researched along with detomidine in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (4.00)	18.7374
1990's	10 (40.00)	18.2507
2000's	6 (24.00)	29.6817
2010's	3 (12.00)	24.3611
2020's	5 (20.00)	2.80

Authors

Authors	Studies
Chhajlani, V; Uhlén, S; Wikberg, JE	1
Elko, EE; Jin, Y; Wilson, S; Yorio, T	1
Hoare, C; Jones, P	1
Salonen, JS	1
Aslanian, V; Renaud, B	1
Faghihi, SM; van Duin, CT; van Miert, AS	1
Castillo-Olivares, JL; Mascías, A; San Román, F; Santos, M; Segura, IA; Tendillo, FJ	1
Clarke, KW; England, GC	1
Black, WD; Celly, CS; McDonell, WN; Young, SS	1
Clark, TP; Schwartz, DD	1
De Graaf, GJ; Jager, LP; Widjaja-Greefkes, HC	1
Grove, DM; Ramsay, EC	1
Futaok, S; Hamaguchi, H; Izumisawa, Y; Katoh, S; Kotani, T; Muir, WW; Seno, T; Tsubakishita, S; Ueda, I; Yamashita, K	1
Kaivosaari, S; Mortensen, J; Salonen, JS; Taskinen, J	1
Kaivosaari, S; Salonen, JS; Taskinen, J	1
Lynch, MJ; Portas, TJ; Vogelnest, L	1
Atalan, G; Cenesiz, M; Kaya, M; Onder, F; Uzun, M; Yildiz, S	1
Janovyak, E; Lizarraga, I	1
Ait-Oudhia, S; Durbin-Johnson, BP; Grimsrud, KN; Jusko, WJ; Mama, KR; Rezende, ML; Rocke, DM; Stanley, SD	1
Bertini, S; Colla, C; Menozzi, A; Placenza, G; Poli, E; Pozzoli, C	1
Hollis, AR; Jolliffe, C; Kaartinen, J; Pascal, M; Van Dijk, J	1
Azari, O; Ebrahimzadeh, F; Mashayekhi, H; Molaei, MM; Nahvi, A; Samimi, AS	1
Aghamiri, SM; Hajian, M; Oroumieh, A; Samimi, AM; Samimi, AS	1
Anderson, NE; Delnatte, P; Dutton, C; Ferro, A; Larouche, CB; Milnes, EL; Skelding, AM	1
Belge, A; Bozkan, Z; Bulut, O; Yaygingul, R	1

Reviews

1 review(s) available for medetomidine and detomidine

Article	Year
Alpha 2 adrenoceptor agonists in the horse--a review. The British veterinary journal, 1996, Volume: 152, Issue:6 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Horses; Hypnotics and Sedatives; Imidazoles; Medetomidine; Respiration; Xylazine	1996

Trials

6 trial(s) available for medetomidine and detomidine

Article	Year
Sedative and physiologic effects of orally administered alpha 2-adrenoceptor agonists and ketamine in cats. Journal of the American Veterinary Medical Association, 2000, Jun-15, Volume: 216, Issue:12 Topics: Administration, Oral; Adrenergic alpha-Agonists; Anesthetics, Dissociative; Animals; Body Temperature; Cats; Female; Heart Rate; Hypnotics and Sedatives; Imidazoles; Injections, Intramuscular; Ketamine; Male; Medetomidine; Oximetry; Oxygen; Prospective Studies; Respiration; Xylazine	2000
Comparison of the mechanical hypoalgesic effects of five α2-adrenoceptor agonists in donkeys. The Veterinary record, 2013, Sep-28, Volume: 173, Issue:12 Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Anesthesia, Intravenous; Animals; Cross-Over Studies; Dexmedetomidine; Double-Blind Method; Equidae; Imidazoles; Medetomidine; Pain Threshold; Time Factors; Xylazine	2013
Behavioural and cardiovascular effects of medetomidine constant rate infusion compared with detomidine for standing sedation in horses. Veterinary anaesthesia and analgesia, 2020, Volume: 47, Issue:1 Topics: Anesthesia; Animals; Behavior, Animal; Brachytherapy; Cross-Over Studies; Female; Heart Rate; Horses; Hypnotics and Sedatives; Imidazoles; Infusions, Intravenous; Male; Medetomidine; Single-Blind Method; Standing Position; Treatment Outcome	2020
Effect of xylazine, detomidine, medetomidine and dexmedetomidine during laparoscopic SCNT embryo transfer on pregnancy rate and some physiological variables in goats. BMC veterinary research, 2022, Mar-15, Volume: 18, Issue:1 Topics: Animals; Dexmedetomidine; Embryo Transfer; Female; Goats; Imidazoles; Laparoscopy; Medetomidine; Pregnancy; Pregnancy Rate; Prospective Studies; Xylazine	2022
A randomized clinical trial to compare ketamine-butorphanol-azaperone-medetomidine and detomidine-etorphine-acepromazine for anesthesia of captive Przewalski horses (Equus przewalskii). American journal of veterinary research, 2022, May-08, Volume: 83, Issue:6 Topics: Acepromazine; Anesthesia; Animals; Azaperone; Butorphanol; Etorphine; Heart Rate; Horses; Hypnotics and Sedatives; Hypoxia; Imidazoles; Immobilization; Ketamine; Medetomidine; Naltrexone; Oxygen; Prospective Studies	2022
Measuring the Effects of Detomidine and Medetomidine Alone and in Combination with Ketamine on Tear Production and Intraocular Pressure in Common Buzzards ( Journal of avian medicine and surgery, 2022, Volume: 36, Issue:3 Topics: Animals; Falconiformes; Intraocular Pressure; Ketamine; Medetomidine; Tonometry, Ocular	2022

Other Studies

18 other study(ies) available for medetomidine and detomidine

Article	Year
Medetomidine stereoisomers delineate two closely related subtypes of idazoxan (imidazoline) I-receptors in the guinea pig. European journal of pharmacology, 1991, Feb-14, Volume: 193, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cerebral Cortex; Dioxanes; Guinea Pigs; Idazoxan; Ileum; Imidazoles; Kinetics; Medetomidine; Muscle, Smooth; Receptors, Adrenergic, alpha; Receptors, Drug; Stereoisomerism; Tritium	1991
Ocular hypotensive effects of medetomidine and its analogs. Journal of ocular pharmacology, 1991,Winter, Volume: 7, Issue:4 Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Animals; Cats; Ciliary Body; Dose-Response Relationship, Drug; Female; Imidazoles; Intraocular Pressure; Isoproterenol; Male; Medetomidine; Ocular Hypertension; Ocular Hypotension; Pupil; Rabbits; Receptors, Adrenergic, alpha	1991
Medetomidine in horses. The Veterinary record, 1991, Nov-23, Volume: 129, Issue:21 Topics: Animals; England; Horses; Hypnotics and Sedatives; Imidazoles; Licensure; Medetomidine	1991
Tissue-specificity of hydroxylation and N-methylation of arylalkylimidazoles. Pharmacology & toxicology, 1991, Volume: 69, Issue:1 Topics: Animals; Brain; Chromatography, High Pressure Liquid; Cytosol; Hydroxylation; Imidazoles; In Vitro Techniques; Kidney; Kinetics; Liver; Lung; Male; Medetomidine; Methylation; Mixed Function Oxygenases; NADP; Organ Specificity; Rats; Rats, Inbred Strains; Stereoisomerism	1991
Changes in serotonin metabolism in the rat raphe magnus and cardiovascular modifications following systemic administration of clonidine and other central alpha 2-agonists: an in vivo voltammetry study. Neuropharmacology, 1989, Volume: 28, Issue:4 Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Dioxanes; Electrochemistry; Heart Rate; Hemodynamics; Idazoxan; Imidazoles; Immunohistochemistry; Male; Medetomidine; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin	1989
Food intake and rumen motility in dwarf goats. Effects of atipamezole on the inhibitory effects induced by detomidine, medetomidine and romifidine. Veterinary research communications, 1994, Volume: 18, Issue:6 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Body Temperature; Eating; Female; Gastrointestinal Motility; Goats; Imidazoles; Infusions, Intravenous; Male; Medetomidine; Rumen	1994
Cardiopulmonary and analgesic effects of xylazine, detomidine, medetomidine, and the antagonist atipamezole in isoflurane-anesthetized swine. Laboratory animal science, 1996, Volume: 46, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesia; Analgesics; Anesthesia; Animals; Blood Pressure; Heart; Heart Rate; Imidazoles; Isoflurane; Lung; Medetomidine; Swine; Vascular Resistance; Xylazine	1996
The comparative hypoxaemic effect of four alpha 2 adrenoceptor agonists (xylazine, romifidine, detomidine and medetomidine) in sheep. Journal of veterinary pharmacology and therapeutics, 1997, Volume: 20, Issue:6 Topics: Adrenergic alpha-Agonists; Analgesics; Anesthetics; Animals; Female; Hemodynamics; Hypoxia; Imidazoles; Injections, Intravenous; Medetomidine; Sheep; Xylazine	1997
Affinity of detomidine, medetomidine and xylazine for alpha-2 adrenergic receptor subtypes. Journal of veterinary pharmacology and therapeutics, 1998, Volume: 21, Issue:2 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cell Line; HT29 Cells; Humans; Hypnotics and Sedatives; Imidazoles; Medetomidine; PC12 Cells; Quinolizines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship; Xylazine	1998
Effects of atipamezole, detomidine and medetomidine on release of steroid hormones by porcine adrenocortical cells in vitro. European journal of pharmacology, 1998, Apr-03, Volume: 346, Issue:1 Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Gonadal Steroid Hormones; Imidazoles; In Vitro Techniques; Medetomidine; Protein Binding; Receptors, Adrenergic, alpha-2; Swine	1998
Cardiovascular effects of medetomidine, detomidine and xylazine in horses. The Journal of veterinary medical science, 2000, Volume: 62, Issue:10 Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Blood Gas Analysis; Blood Pressure; Cardiovascular System; Dose-Response Relationship, Drug; Heart Rate; Horses; Imidazoles; Injections, Intravenous; Medetomidine; Receptors, Adrenergic, alpha; Respiration; Xylazine	2000
High-performance liquid chromatographic method combining radiochemical and ultraviolet detection for determination of low activities of uridine 5'-diphosphate-glucuronosyltransferase. Analytical biochemistry, 2001, May-15, Volume: 292, Issue:2 Topics: Aminobiphenyl Compounds; Amitriptyline; Chromatography, High Pressure Liquid; Glucuronides; Glucuronosyltransferase; Humans; Imidazoles; Kinetics; Medetomidine; Microsomes, Liver; Nitrophenols; Radiochemistry; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Time Factors; Ultraviolet Rays	2001
N-Glucuronidation of some 4-arylalkyl-1H-imidazoles by rat, dog, and human liver microsomes. Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:3 Topics: Animals; Chromatography, High Pressure Liquid; Detergents; Dogs; Enzyme Activation; Glucuronosyltransferase; Humans; Imidazoles; In Vitro Techniques; Isoenzymes; Kinetics; Male; Medetomidine; Microsomes, Liver; Octoxynol; Rats; Rats, Wistar; Species Specificity; Stereoisomerism; Structure-Activity Relationship	2002
Comparison of etorphine-detomidine and medetomidine-ketamine anesthesia in captive addax (Addax nasomaculatus). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2003, Volume: 34, Issue:3 Topics: Anesthetics, Combined; Anesthetics, Dissociative; Animals; Animals, Zoo; Antelopes; Etorphine; Female; Hypnotics and Sedatives; Imidazoles; Immobilization; Injections, Intramuscular; Ketamine; Male; Medetomidine; Narcotic Antagonists	2003
Effects of xylazine, medetomidine, detomidine, and diazepam on sedation, heart and respiratory rates, and cloacal temperature in rock partridges (Alectoris graeca). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2006, Volume: 37, Issue:2 Topics: Animals; Cloaca; Diazepam; Female; Galliformes; Heart Rate; Hypnotics and Sedatives; Imidazoles; Injections, Intramuscular; Male; Medetomidine; Random Allocation; Respiration; Time Factors; Xylazine	2006
Pharmacokinetic and pharmacodynamic analysis comparing diverse effects of detomidine, medetomidine, and dexmedetomidine in the horse: a population analysis. Journal of veterinary pharmacology and therapeutics, 2015, Volume: 38, Issue:1 Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Horses; Imidazoles; Male; Medetomidine; Models, Biological	2015
Effects of selective α Journal of veterinary pharmacology and therapeutics, 2018, Volume: 41, Issue:2 Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Brimonidine Tartrate; Bronchi; Carbachol; Electric Stimulation; Horses; Imidazoles; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Xylazine	2018
Evaluation of the sedative and physiological effects of xylazine, detomidine, medetomidine and dexmedetomidine in goats. Veterinary medicine and science, 2022, Volume: 8, Issue:3 Topics: Adrenergic Agonists; Animals; Dexmedetomidine; Goats; Hypnotics and Sedatives; Imidazoles; Medetomidine; Xylazine	2022