mechlorethamine and mustard gas

mechlorethamine has been researched along with mustard gas in 83 studies

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-199044 (53.01)18.7374
1990's4 (4.82)18.2507
2000's9 (10.84)29.6817
2010's15 (18.07)24.3611
2020's11 (13.25)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Weigand, DA1
Bojanić, N; Bosković, B; Milosavljević, Z; Vojvodić, V1
Gray, P; Lewis, K; Masta, A; Phillips, D1
Arad-Yellin, R; Brodsky, B; Green, BS; Nyska, A; Wormser, U1
Graham, JS; Hackley, BE; Hamilton, T; Moeller, R; Okerberg, C; Skelton, HG; Smith, KJ; Smith, WJ1
Davidson, KA; Faust, RA; King, J; Opresko, DM; Ross, RH; Talmage, SS; Watson, AP; Young, RA1
Baeza-Squiban, A; Calvet, J; Marano, F; Rappeneau, S1
BERNAL, E; FONG, J1
PAOLINO, W1
BLUM, B; FONG, J1
HESTON, WE2
BOVO, G; D'AGNOLO, B1
WOLTERHOFF, H1
DALL'ARMELLINA, PJ1
RINGENBACH, MG1
RAVINA, A1
DANNEBERG, P; DRUCKREY, H; KAISER, K; LO, HW; MECKE, R; NIEPER, HA; SCHMAHL, D1
BOIRON, M; PAOLETTI, C; TRUHAUT, R; TUBIANA, M1
SCHOLTISSEK, C1
GOODLAD, GA1
DAVIDSON, JN; DRYSDALE, RB; HOPKINS, A; SMELLIE, RM; THOMSON, RY1
HAROLD, FM; ZIPORIN, ZZ1
COSTANTINI, AV; FARBER, SM; METTIER, SR; PETRAKIS, NL; WOOD, DA1
DEYSSON, G; TRUHAUT, R1
GREEN, TH1
SCHWENKENBECHER, W1
HENNE, HF1
SALZGEBER, B1
HELLEINER, CW; WALKER, IG1
HARTMAN, FW; KELLY, AR; LOGRIPPO, GA1
BARANCEWICZ, J; BAZAŁA, L; CZEZOWSKA, Z1
AUERBACH, C; JENSEN, KA; KIRK, I; MOSER, H; MYLORIE, A; STEVENS, CM; WESTERGAARD, M1
HERRIOTT, RM; TENBROECK, C1
BACQ, ZM; CHARLIER, R; KLUTZ, A1
BENINI, S; SECCO, C; VITTONE, A1
ROMEO, G1
DI LOLLO, F; TERZANI, A; WEBER, A1
NINNI, M1
PEDERSEN, E1
PHILIPS, FS1
Dubey, DK; Gupta, AK; Kanaujia, PK; Palit, M; Pardasani, D1
Dubey, DK; Gupta, AK; Jain, R; Palita, M; Pardasania, D1
Boisvieux-Ulrich, E; Brenner, C; Breton, P; Daulon, S; Deniaud, A; Lemaire, C; Marano, F; Sourdeval, M; Taysse, L1
Dillman, JF; Minsavage, GD1
Bhattacharya, SK; Fernandez, C; Hom, GG; Hom, LG1
MAUMENEE, AE; SCHOLZ, RO1
BUSCHKE, W; FRIEDENWALD, JS; SCHOLZ, RO1
GRAEF, I; KARNOFSKY, DA; SMITH, HW1
Billack, B; Pino, MA1
Ganesan, K; Sharma, M; Vijayaraghavan, R1
GELLHORN, A; ROSE, HM1
UHDE, GI1
CORNMAN, I; ORMSBEE, RA1
Agrawal, OP; Sharma, M; Vijayaraghavan, R1
Alavi, SA; Falahati, F; Jadidi, K; Naderi, M1
Anumolu, SS; Babin, MC; Beloni, J; Desantis, A; Deshmukh, M; Gallo, MA; Gerecke, DR; Gordon, MK; Hahn, RA; Heindel, ND; Lacey, CJ; Schlager, JJ; Sinko, PJ; Svoboda, KK1
Anumolu, SS; Deshmukh, M; Gerecke, D; Laskin, J; Menjoge, AR; Sinko, PJ; Stein, S1
DIXON, M; NEEDHAM, DM1
Pant, JC; Pant, SC; Sharma, M; Vijayaraghavan, R1
Agarwal, C; Agarwal, R; Ammar, DA; Enzenauer, RW; Inturi, S; Jain, AK; Kompella, UB; Petrash, JM; Tewari-Singh, N; Tyagi, P1
Billack, B; Pietka-Ottlik, M; Pino, MA1
Kehe, K; Schrettl, V; Steinritz, D; Thiermann, H1
Agarwal, R; Jain, AK; Orlicky, DJ; Tewari-Singh, N; White, CW1
MOORE, AM; ROCKMAN, JB1
Ikeda, T; Kondo, T; Kurimata, N; Nagashima, H; Nagoya, T; Seto, Y; Unoke, S1
Balszuweit, F; Birtel, M; Burckhardt-Boer, W; Bürkle, A; Debiak, M; Lex, K; Mangerich, A; Martello, R; Ponath, V; Schmidt, A; Siegert, M; Steinritz, D; Strobelt, R; Thiermann, H1
Casillas, RP; Composto, GM; Croutch, CR; Gerecke, DR; Guillon, CD; Heck, DE; Heindel, ND; Joseph, LB; Lacey, CJ; Laskin, DL; Laskin, JD; Wohlman, IM1
Smith, SL1
Agarwal, R; Ammar, DA; Enzenauer, RW; Goswami, DG; Kant, R; Kumar, D; Petrash, JM; Tewari-Singh, N1
Gudermann, T; John, H; Kehe, K; Kranawetvogl, A; Lang, S; Popp, T; Rothmiller, S; Schmidt, A; Siegert, M; Steinritz, D; Thiermann, H1
Heck, DE; Jan, YH; Laskin, DL; Laskin, JD1
Armeli, F; Businaro, R; Laskin, DL; Maggi, E; Murray, A1
Bauer, AK; Brown, JM; Cruz-Hernandez, A; Evans, CM; Harder, A; Mendoza, RP; Nguyen, K; Tewari-Singh, N1
Araj, H; Tseng, H; Yeung, DT1
Agarwal, R; Mishra, N1
An, S; Anwar, K; Ashraf, M; Djalilian, AR; Ghassemi, M; Koganti, R; Lee, H; Shen, X1
Bargagna-Mohan, P; Mohan, R; Mullane, E; Paramo, R; Umejiego, E; Zafiris, A1
Guenova, E; Ortiz-Romero, PL; Poligone, B; Querfeld, C1
Balne, PK; Chaurasia, SS; Mohan, RR; Simkins, K; Sinha, NR; Suleiman, L; Tripathi, R1
Ashraf, MJ; Baharnoori, SM; Cheraghpour, M; Cheraqpour, K; Chow, C; Djalilian, AR; Ghassemi, M; Huang, X; Koganti, R; Mirshahi, R; Momenaei, B; Nguyen, T; Shahjahan, S; Soleimani, M1
Alemi, H; Chen, Y; Dana, R; Dehghani, S; Dohlman, TH; Forouzanfar, K; Musayeva, A; Narimatsu, A; Sharifi, S; Surico, PL; Wang, S; Yin, J1

Reviews

5 review(s) available for mechlorethamine and mustard gas

ArticleYear
Chemical warfare agents: estimating oral reference doses.
    Reviews of environmental contamination and toxicology, 1998, Volume: 156

    Topics: Air Pollutants; Animals; Arsenic Poisoning; Arsenicals; Chemical Warfare Agents; Cholinesterase Inhibitors; Cyanides; Environmental Monitoring; Hazardous Waste; Humans; Mechlorethamine; Mustard Compounds; Mustard Gas; No-Observed-Adverse-Effect Level; Rats; Reference Values; Risk Assessment; United States

1998
Ocular effects of exposure to industrial chemicals: clinical management and proteomic approaches to damage assessment.
    Cutaneous and ocular toxicology, 2007, Volume: 26, Issue:3

    Topics: Accidents, Occupational; Acids; Alkalies; Ammonia; Burns, Chemical; Chemical Warfare Agents; Chlorine Compounds; Disasters; Eye; Eye Burns; Eye Proteins; Hazardous Substances; Humans; Isocyanates; Mechlorethamine; Mustard Gas; Proteins; Proteomics; Risk Assessment; Wound Healing

2007
Nutraceuticals as potential therapeutics for vesicant-induced pulmonary fibrosis.
    Annals of the New York Academy of Sciences, 2020, Volume: 1480, Issue:1

    Topics: Animals; Chemical Warfare Agents; Dietary Supplements; Disease Models, Animal; Humans; Irritants; Mechlorethamine; Mustard Gas; Pulmonary Fibrosis

2020
Research models of sulfur mustard- and nitrogen mustard-induced ocular injuries and potential therapeutics.
    Experimental eye research, 2022, Volume: 223

    Topics: Animals; Chemical Warfare Agents; Cornea; Eye Injuries; Humans; Irritants; Mechlorethamine; Mustard Gas

2022
Mechanism of action of chlormethine gel in mycosis fungoides.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2023, Volume: 37, Issue:9

    Topics: Humans; Mechlorethamine; Mustard Gas; Mycosis Fungoides; Quality of Life; Skin Neoplasms; Tumor Microenvironment

2023

Other Studies

78 other study(ies) available for mechlorethamine and mustard gas

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Chemical warfare.
    Journal of the American Academy of Dermatology, 1989, Volume: 21, Issue:2 Pt 1

    Topics: Chemical Warfare Agents; Humans; Mechlorethamine; Mustard Compounds; Mustard Gas; Skin Diseases

1989
The protective effect of different drugs in rats poisoned by sulfur and nitrogen mustards.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1985, Volume: 5, Issue:6 Pt 2

    Topics: Animals; Antidotes; Body Weight; Chinchilla; Cholinesterases; Female; Lethal Dose 50; Male; Mechlorethamine; Mustard Compounds; Mustard Gas; Rabbits; Rats; Skin; Spleen

1985
Modulation of mustard toxicity by tacrine.
    Biochemical pharmacology, 1994, Feb-09, Volume: 47, Issue:3

    Topics: Animals; Cell Survival; Cells, Cultured; DNA; Female; HeLa Cells; Humans; Male; Mechlorethamine; Mustard Gas; Rats; Rats, Sprague-Dawley; Tacrine

1994
Protective effect of povidone-iodine ointment against skin lesions induced by sulphur and nitrogen mustards and by non-mustard vesicants.
    Archives of toxicology, 1997, Volume: 71, Issue:3

    Topics: Animals; Anti-Infective Agents, Local; Chemical Warfare Agents; Guinea Pigs; Irritants; Magnetic Resonance Spectroscopy; Male; Mechlorethamine; Mustard Gas; Ointments; Povidone-Iodine; Skin; Skin Diseases

1997
Histopathologic and immunohistochemical features in human skin after exposure to nitrogen and sulfur mustard.
    The American Journal of dermatopathology, 1998, Volume: 20, Issue:1

    Topics: Autoantigens; Biomarkers; Carrier Proteins; Cell Adhesion Molecules; Collagen; Collagen Type XVII; Culture Techniques; Cytoskeletal Proteins; Dermatologic Agents; Dystonin; Humans; Immunohistochemistry; Kalinin; Mechlorethamine; Mustard Gas; Nerve Tissue Proteins; Non-Fibrillar Collagens; Skin; Skin Diseases

1998
Efficient protection of human bronchial epithelial cells against sulfur and nitrogen mustard cytotoxicity using drug combinations.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 58, Issue:1

    Topics: Acetylcysteine; Bronchi; Cells, Cultured; Citrulline; Cytoprotection; Dose-Response Relationship, Drug; Doxycycline; Drug Combinations; Drug Interactions; Epithelial Cells; Humans; Mechlorethamine; Mercaptoethylamines; Methenamine; Mustard Gas; NG-Nitroarginine Methyl Ester; Niacinamide; Protective Agents; Radiation-Protective Agents; Tetrazolium Salts; Thiourea

2000
In vitro action of sulfur mustard and chloroethylamine derivatives upon antigenicity of influenza A (PR8) virus.
    Journal of immunology (Baltimore, Md. : 1950), 1953, Volume: 70, Issue:1

    Topics: Humans; In Vitro Techniques; Influenza, Human; Mechlorethamine; Mustard Gas; Nitrogen Mustard Compounds; Orthomyxoviridae

1953
[Chemotherapy of tumors. I. Mustard gas and nitrogen mustard derivatives; synthetic review].
    Minerva medica, 1953, Jan-06, Volume: 44, Issue:1-2

    Topics: Humans; Mechlorethamine; Mustard Gas; Neoplasms; Nitrogen Mustard Compounds

1953
Action of mustards on interfering, hemagglutinating and eluting capacities of influenza A (PR8) virus.
    Journal of immunology (Baltimore, Md. : 1950), 1953, Volume: 71, Issue:1

    Topics: Hemagglutination Tests; Humans; Hydrocarbons; Influenza, Human; Mechlorethamine; Mustard Gas; Mustard Plant; Nitrogen Mustard Compounds; Orthomyxoviridae; Viruses

1953
Occurrence of tumors in mice injected subcutaneously with sulfur mustard and nitrogen mustard.
    Journal of the National Cancer Institute, 1953, Volume: 14, Issue:1

    Topics: Animals; Mechlorethamine; Mice; Mustard Gas; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds

1953
[Nitrogen mustard gas therapy of tuberculous lymphoma].
    Schweizerische medizinische Wochenschrift, 1953, Nov-14, Volume: 83, Issue:46

    Topics: Lymph Nodes; Lymphoma; Mechlorethamine; Mustard Gas; Mustard Plant; Nitrogen; Nitrogen Mustard Compounds; Tuberculosis; Tuberculosis, Lymph Node

1953
[Further results of comparative therapeutic experiments with mustard gas in inoperable cancer of the bladder of different cell types].
    Zeitschrift fur Urologie, 1953, Volume: 46, Issue:9

    Topics: Abdominal Cavity; Humans; Mechlorethamine; Mustard Gas; Neoplasms; Nitrogen Mustard Compounds; Urinary Bladder Neoplasms

1953
[Mustard gas and urethane; their effects on the pelvic metastasis of cancer of the uterine cervix].
    Prensa medica argentina, 1955, Jul-15, Volume: 42, Issue:28

    Topics: Female; Humans; Mechlorethamine; Mustard Gas; Neoplasms; Nitrogen Mustard Compounds; Pelvic Neoplasms; Pelvis; Urethane; Uterine Cervical Neoplasms

1955
[Remarquable results with yperite nitrate in two cases of Hodgkin's disease].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1956, Volume: 133, Issue:1

    Topics: Hodgkin Disease; Mechlorethamine; Mustard Gas; Nitrates; Nitrogen Mustard Compounds; Nitrogen Oxides

1956
[Treatment of serous effusions of tumoral origin by nitrogen yperite].
    La Presse medicale, 1956, May-12, Volume: 64, Issue:38

    Topics: Mechlorethamine; Mustard Gas; Neoplasms; Nitrogen; Nitrogen Mustard Compounds

1956
[Comparative investigation of the chemotherapeutic action of N-oxide-mustard gas and other alkylating compounds in rat tumors].
    Arzneimittel-Forschung, 1956, Volume: 6, Issue:9

    Topics: Alkylating Agents; Animals; Ethylenediamines; Mechlorethamine; Mustard Gas; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; Oxides; Rats

1956
[Inhibition of hemoglobin metabolism in reticulocytes by beta-chloroethyl compounds].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Nov-18, Volume: 150, Issue:6

    Topics: Hemoglobins; Humans; Mechlorethamine; Mustard Gas; Nitrogen Mustard Compounds; Reticulocytes

1956
[Effect of nitrogen mustard gas and colchicine on serum proteins].
    Zeitschrift fur Krebsforschung, 1956, Volume: 61, Issue:4

    Topics: Blood Proteins; Colchicine; Elements; Humans; Hydrocarbons; Mechlorethamine; Mustard Gas; Mustard Plant; Nitrogen; Nitrogen Mustard Compounds

1956
Cross linking of collagen by S- and N-mustards.
    Biochimica et biophysica acta, 1957, Volume: 25, Issue:1

    Topics: Collagen; Mechlorethamine; Mustard Gas; Mustard Plant; Nitrogen Mustard Compounds

1957
Some effects of nitrogen and sulphur mustards on the metabolism of nucleic acids in mammalian cells.
    British journal of cancer, 1958, Volume: 12, Issue:1

    Topics: Mechlorethamine; Mustard Gas; Nitrogen; Nitrogen Mustard Compounds; Nucleic Acids

1958
Effect of nitrogen and sulfur mustard on nucleic acid synthesis in Escherichia coli.
    Biochimica et biophysica acta, 1958, Volume: 28, Issue:3

    Topics: Escherichia coli; Mechlorethamine; Mustard Gas; Nitrogen; Nitrogen Mustard Compounds; Nucleic Acids

1958
Preliminary clinical evaluation of 1, 2-bis(beta-chloroethylthylthio) ethane (SM-1) in patients with advanced lymphomas and neoplastic diseases.
    Annals of the New York Academy of Sciences, 1958, Apr-24, Volume: 68, Issue:3

    Topics: Antineoplastic Agents; Ethane; Lymphoma; Mechlorethamine; Mustard Gas; Myosin-Light-Chain Kinase; Neoplasms; Nitrogen Mustard Compounds; Peptide Fragments

1958
[Comparison of the antimitotic properties of mechlorethamine-N-oxide with those of its sulfur homologue (yperite) and of nitrogen (nitrogen mustard)].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1959, Feb-02, Volume: 248, Issue:5

    Topics: Antimitotic Agents; Mechlorethamine; Mustard Gas; Nitrogen; Nitrogen Mustard Compounds; Oxides; Sulfur

1959
Hemisulfur mustard in the palliation of patients with metastatic ovarian carcinoma.
    Obstetrics and gynecology, 1959, Volume: 13, Issue:4

    Topics: Antineoplastic Agents; Carcinoma, Ovarian Epithelial; Female; Humans; Mechlorethamine; Mustard Gas; Mustard Plant; Neoplasms; Neoplasms, Glandular and Epithelial; Nitrogen Mustard Compounds; Ovarian Neoplasms; Ovary

1959
[Results of treatment of malignant tumors with N-mustard gas-phosphamide ester (endoxan)].
    Therapie der Gegenwart, 1959, Volume: 98, Issue:6

    Topics: Cyclophosphamide; Dimethoate; Esters; Mechlorethamine; Mustard Gas; Neoplasms; Nitrogen Mustard Compounds

1959
[On changes in the iron level and serum protein fractions after cytostatic therapy with N-oxide mustard gas and a nitrogen mustard phosphamide ester].
    Langenbecks Archiv fur klinische Chirurgie ... vereinigt mit Deutsche Zeitschrift fur Chirurgie, 1961, Volume: 297

    Topics: Antineoplastic Agents; Blood Proteins; Cytostatic Agents; Dimethoate; Iron; Mechlorethamine; Mustard Gas; Nitrogen Mustard Compounds; Oxides; Serum Albumin; Serum Albumin, Human; Serum Globulins

1961
[Study of phocomelus monsters obtained from chick embryo with the aid of nitrogen mustard gas].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1962, Volume: 156

    Topics: Animals; Chick Embryo; Ectromelia; Elements; Mechlorethamine; Mustard Gas; Mustard Plant; Nitrogen

1962
The sensitivity of cultured mammalian cells in different stages of the division cycle to nitrogen and sulfur mustards.
    Cancer research, 1963, Volume: 23

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Mammals; Mechlorethamine; Mustard Gas; Nitrogen; Tissue Culture Techniques

1963
Four-year study concerning the inactivation of viruses in blood and plasma.
    Gastroenterology, 1955, Volume: 28, Issue:2

    Topics: Animals; Blood; Encephalomyelitis; Encephalomyelitis, Equine; Ethylene Oxide; Horses; Mechlorethamine; Mustard Gas; Nitrogen Mustard Compounds; Plasma; Propionates; Viruses

1955
[Use of nitrogen yperite in allergic bronchial asthma].
    Polski tygodnik lekarski, 1955, Apr-18, Volume: 10, Issue:16

    Topics: Asthma; Mechlorethamine; Mustard Gas; Nitrogen; Nitrogen Mustard Compounds

1955
Carcinogenic action of the mustards.
    Journal of the National Cancer Institute, 1950, Volume: 11, Issue:2

    Topics: Carcinogens; Mechlorethamine; Mustard Gas; Mustard Plant; Nitrogen Mustard Compounds

1950
Biological action of 'mustard gas' compounds.
    Nature, 1950, Dec-16, Volume: 166, Issue:4233

    Topics: Mechlorethamine; Mustard Compounds; Mustard Gas; Nitrogen Mustard Compounds

1950
Mustard inactivated rabies vaccine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1950, Volume: 75, Issue:2

    Topics: Humans; Hydrocarbons; Mechlorethamine; Mustard Gas; Mustard Plant; Nitrogen Mustard Compounds; Rabies; Rabies Vaccines; Vaccines, Inactivated

1950
[Modifications of the electrocardiogram of the dog after intravenous injection of a small quantity of yperite or of monobromacetate].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1951, Sep-10, Volume: 233, Issue:11

    Topics: Animals; Dogs; Electrocardiography; Injections, Intravenous; Mechlorethamine; Mustard Gas; Nitrogen Mustard Compounds

1951
[Auxiliary use of mustard gas derivatives in streptomycin therapy of meningeal tuberculosis].
    Il Policlinico. Sezione pratica, 1951, Nov-26, Volume: 58, Issue:48

    Topics: Mechlorethamine; Mustard Gas; Nitrogen Mustard Compounds; Streptomycin; Tuberculosis; Tuberculosis, Meningeal

1951
[Tentative treatment with nitrogen yperite in some childhood anemias with erythroblastosis; subacute erythremic myelosis and Cooley's anemia].
    Minerva medica, 1949, Sep-08, Volume: 40, Issue:44 Pt 2

    Topics: Anemia; beta-Thalassemia; Hematopoietic System; Humans; Leukemia, Erythroblastic, Acute; Mechlorethamine; Mustard Gas; Nitrogen; Nitrogen Mustard Compounds

1949
[Preliminary therapeutic results with nitrogen yperite preparations].
    Minerva medica, 1949, Sep-08, Volume: 40, Issue:44 Pt 2

    Topics: Humans; Mechlorethamine; Mustard Gas; Nitrogen; Nitrogen Mustard Compounds

1949
[The leucolytique action of blood serum in the mechanism of action of nitrogenous derivatives of hypérite].
    Experientia, 1950, Jan-15, Volume: 6, Issue:1

    Topics: Leukocytes; Mechlorethamine; Mustard Gas; Nitrogen; Nitrogen Mustard Compounds; Serum

1950
On treatment of spontaneous leukemia in mice with nitrogenized mustard gas.
    Acta pathologica et microbiologica Scandinavica, 1950, Volume: 27, Issue:1

    Topics: Animals; Leukemia; Mechlorethamine; Mice; Mustard Gas; Nitrogen Mustard Compounds

1950
Recent contributions to the pharmacology of bis(2-haloethyl) amines and sulfides.
    The Journal of pharmacology and experimental therapeutics, 1950, Volume: 99, Issue:4:2

    Topics: Amines; Mechlorethamine; Mustard Gas; Nitrogen Mustard Compounds; Sulfides

1950
Gas chromatography-mass spectrometry analysis of trifluoroacetyl derivatives of precursors of nitrogen and sulfur mustards for verification of chemical weapons convention.
    Journal of chromatography. A, 2004, Dec-03, Volume: 1059, Issue:1-2

    Topics: Chemical Warfare; Gas Chromatography-Mass Spectrometry; Mechlorethamine; Mustard Gas

2004
On-matrix derivatisation-extraction of precursors of nitrogen- and sulfur-mustards for verification of chemical weapons convention.
    Journal of chromatography. A, 2005, May-27, Volume: 1076, Issue:1-2

    Topics: Calibration; Chemical Warfare Agents; Gas Chromatography-Mass Spectrometry; Mechlorethamine; Mustard Gas; Reference Standards; Reproducibility of Results

2005
Inhibition of caspase-dependent mitochondrial permeability transition protects airway epithelial cells against mustard-induced apoptosis.
    Apoptosis : an international journal on programmed cell death, 2006, Volume: 11, Issue:9

    Topics: Animals; Apoptosis; Azoles; Caspases; Cell Adhesion; Cell Membrane Permeability; Cells, Cultured; Cyclosporine; HeLa Cells; Humans; Isoindoles; Mechlorethamine; Melatonin; Mice; Mitochondria; Models, Biological; Multiprotein Complexes; Mustard Gas; Organoselenium Compounds; Proto-Oncogene Proteins c-bcl-2; Respiratory Mucosa; Tumor Suppressor Protein p53

2006
Bifunctional alkylating agent-induced p53 and nonclassical nuclear factor kappaB responses and cell death are altered by caffeic acid phenethyl ester: a potential role for antioxidant/electrophilic response-element signaling.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:1

    Topics: Alkylating Agents; Antioxidants; Blotting, Western; Caffeic Acids; Cell Death; Electrophoresis, Polyacrylamide Gel; Genes, p53; Genes, Reporter; Humans; Keratinocytes; L-Lactate Dehydrogenase; Luciferases; Mechlorethamine; Mustard Gas; NF-kappa B; Phenylethyl Alcohol; Receptors, Aryl Hydrocarbon; Response Elements; Signal Transduction; Transfection

2007
The histopathology of the ocular lesions produced by the sulfur and nitrogen mustard.
    Bulletin of the Johns Hopkins Hospital, 1948, Volume: 82, Issue:2

    Topics: Cornea; Ethylamines; Eye; Mechlorethamine; Mustard Gas; Sulfides; Sulfur

1948
Effects of mustard and nitrogen mustard on mitotic and wound healing activities of the corneal epithelium.
    Bulletin of the Johns Hopkins Hospital, 1948, Volume: 82, Issue:2

    Topics: Cornea; Epithelium, Corneal; Ethylamines; Mechlorethamine; Mustard Gas; Mustard Plant; Sulfides; Wound Healing

1948
Studies on the mechanism of action of the nitrogen and sulfur mustards in vivo.
    The American journal of pathology, 1948, Volume: 24, Issue:2

    Topics: Ethylamines; Mechlorethamine; Mustard Gas; Nitrogen; Sulfides

1948
Reduction of vesicant toxicity by butylated hydroxyanisole in A-431 skin cells.
    Cutaneous and ocular toxicology, 2008, Volume: 27, Issue:3

    Topics: Antioxidants; Azoles; Buthionine Sulfoximine; Butylated Hydroxyanisole; Cell Line, Tumor; Chemical Warfare Agents; DNA Fragmentation; Epidermal Cells; Glutathione; Humans; Isoindoles; Mechlorethamine; Molecular Structure; Mustard Gas; Organoselenium Compounds

2008
Comparison of toxicity of selected mustard agents by percutaneous and subcutaneous routes.
    Indian journal of experimental biology, 2008, Volume: 46, Issue:12

    Topics: Administration, Cutaneous; Animals; Body Weight; Female; Injections, Subcutaneous; Mechlorethamine; Mice; Mustard Gas; Survival Rate; Toxicity Tests

2008
Inactivation of influenza virus with sulfur and nitrogen mustards.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1947, Volume: 65, Issue:1

    Topics: Ethylamines; Humans; Influenza, Human; Mechlorethamine; Mustard Gas; Nitrogen Mustard Compounds; Orthomyxoviridae; Sulfides; Sulfur

1947
Burns of the upper respiratory tract and eyes from a nitrogen mustard gas (1149); a clinical study.
    Archives of otolaryngology, 1946, Volume: 44, Issue:6

    Topics: Burns; Ethylamines; Eye Injuries; Gas Poisoning; Humans; Mechlorethamine; Mustard Gas; Mustard Plant; Nitrogen; Respiratory System

1946
The different susceptibilities to nitrogen mustard of normal and malignant tissues growing in vitro.
    Federation proceedings, 1947, Volume: 6, Issue:1

    Topics: Humans; In Vitro Techniques; Mechlorethamine; Mustard Gas; Sulfides

1947
Comparative toxic effect of nitrogen mustards (HN-1, HN-2, and HN-3) and sulfur mustard on hematological and biochemical variables and their protection by DRDE-07 and its analogues.
    International journal of toxicology, 2010, Volume: 29, Issue:4

    Topics: Alkaline Phosphatase; Amifostine; Animals; Body Weight; Female; Lethal Dose 50; Leukocyte Count; Mechlorethamine; Mice; Mustard Gas; Organ Size; Spleen; Thiobarbituric Acid Reactive Substances; Transaminases

2010
The effect of sulfur mustard and nitrogen mustard on corneal collagen degradation induced by the enzyme collagenase.
    Cutaneous and ocular toxicology, 2010, Volume: 29, Issue:4

    Topics: Alkylating Agents; Animals; Cattle; Collagen; Cornea; Drug Therapy, Combination; Hydroxyproline; Irritants; Matrix Metalloproteinase Inhibitors; Mechlorethamine; Mustard Gas

2010
Doxycycline hydrogels as a potential therapy for ocular vesicant injury.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2010, Volume: 26, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Basement Membrane; Corneal Diseases; Corneal Edema; Corneal Neovascularization; Doxycycline; Epithelium, Corneal; Eye; Eye Injuries; Hydrogels; Irritants; Male; Mechlorethamine; Mustard Gas; Nitrogen Mustard Compounds; Rabbits; Tetracyclines

2010
Doxycycline hydrogels with reversible disulfide crosslinks for dermal wound healing of mustard injuries.
    Biomaterials, 2011, Volume: 32, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Biocompatible Materials; Chemical Warfare Agents; Cross-Linking Reagents; Disulfides; Doxycycline; Humans; Hydrogels; Hydrogen Peroxide; Irritants; Materials Testing; Mechlorethamine; Mice; Molecular Structure; Mustard Gas; Oxidants; Skin; Wound Healing

2011
Biochemical research on chemical warfare agents.
    Nature, 1946, Sep-28, Volume: 158

    Topics: Chemical Warfare; Chemical Warfare Agents; Gas Poisoning; Humans; Mechlorethamine; Mustard Gas; Nitrogen Mustard Compounds; Sulfides

1946
Nitrogen and sulphur mustard induced histopathological observations in mouse visceral organs.
    Journal of environmental biology, 2010, Volume: 31, Issue:6

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chemical Warfare Agents; Female; Kidney Diseases; Mechlorethamine; Mice; Mustard Gas; Skin Diseases; Splenic Diseases

2010
Silibinin, dexamethasone, and doxycycline as potential therapeutic agents for treating vesicant-inflicted ocular injuries.
    Toxicology and applied pharmacology, 2012, Oct-01, Volume: 264, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Chemical Warfare Agents; Corneal Diseases; Cyclooxygenase 2; Dexamethasone; Doxycycline; Drug Therapy, Combination; Epithelium, Corneal; In Vitro Techniques; Irritants; Mechlorethamine; Mustard Gas; Rabbits; Silybin; Silymarin; Vascular Endothelial Growth Factor A

2012
Selected ebselen analogs reduce mechlorethamine toxicity in vitro.
    Cutaneous and ocular toxicology, 2014, Volume: 33, Issue:1

    Topics: Antioxidants; Azoles; Cell Line, Tumor; Cell Survival; Humans; Isoindoles; Lipid Peroxidation; Malondialdehyde; Mechlorethamine; Microscopy, Phase-Contrast; Molecular Structure; Mustard Gas; Organoselenium Compounds; Skin; Structure-Activity Relationship

2014
Modified immunoslotblot assay to detect hemi and sulfur mustard DNA adducts.
    Chemico-biological interactions, 2013, Dec-05, Volume: 206, Issue:3

    Topics: Cell Line; Chemical Warfare Agents; DNA Adducts; DNA Damage; Humans; Immunoblotting; Keratinocytes; Mechlorethamine; Mustard Gas; Skin

2013
Cutaneous injury-related structural changes and their progression following topical nitrogen mustard exposure in hairless and haired mice.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Animals; Blister; Chemical Warfare Agents; Dermis; Disease Progression; Epidermis; Hyperkeratosis, Epidermolytic; Mechlorethamine; Mice; Mice, Hairless; Mice, Inbred C57BL; Mustard Gas; Necrosis

2014
A study of human hypersensitivity to compounds of the mustard gas type.
    Canadian journal of research. Section E, Medical sciences, 1950, Volume: 28, Issue:4

    Topics: Gases; Humans; Hypersensitivity; Mechlorethamine; Mustard Gas; Nitrogen Mustard Compounds

1950
Identification of chemical warfare agents from vapor samples using a field-portable capillary gas chromatography/membrane-interfaced electron ionization quadrupole mass spectrometry instrument with Tri-Bed concentrator.
    Journal of chromatography. A, 2015, Aug-07, Volume: 1406

    Topics: Chemical Warfare Agents; Chemistry Techniques, Analytical; Gas Chromatography-Mass Spectrometry; Gases; Mechlorethamine; Mustard Gas; Organophosphates; Sarin; Soman

2015
Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences.
    Toxicology letters, 2016, Feb-26, Volume: 244

    Topics: Adenosine Diphosphate Ribose; Antidotes; Antineoplastic Agents, Alkylating; Cell Line; Cell Proliferation; Cell Survival; Chemical Warfare Agents; Chlorambucil; DNA Adducts; Dose-Response Relationship, Drug; Drug Synergism; Genomic Instability; Humans; Keratinocytes; Mechlorethamine; Micronuclei, Chromosome-Defective; Mustard Gas; Nitrogen Mustard Compounds; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Signal Transduction; Time Factors

2016
Mustard vesicants alter expression of the endocannabinoid system in mouse skin.
    Toxicology and applied pharmacology, 2016, 07-15, Volume: 303

    Topics: Alkylating Agents; Amidohydrolases; Animals; Chemical Warfare Agents; Female; Irritants; Male; Mechlorethamine; Mice; Mice, Hairless; Mustard Gas; PPAR alpha; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Skin

2016
War! What is it good for? Mustard gas medicine.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2017, 02-27, Volume: 189, Issue:8

    Topics: Antineoplastic Agents; Chemical Warfare Agents; Drug Discovery; History, 20th Century; Humans; Mechlorethamine; Mustard Gas; World War I; World War II

2017
Acute corneal injury in rabbits following nitrogen mustard ocular exposure.
    Experimental and molecular pathology, 2019, Volume: 110

    Topics: Acute Disease; Animals; Chemical Warfare Agents; Cornea; Corneal Injuries; Cyclooxygenase 2; Humans; Immunohistochemistry; Interleukin-8; Male; Matrix Metalloproteinase 9; Mechlorethamine; Mustard Gas; Rabbits; Vascular Endothelial Growth Factor A

2019
Skin sensitizing effects of sulfur mustard and other alkylating agents in accordance to OECD guidelines.
    Toxicology letters, 2019, Oct-10, Volume: 314

    Topics: Biomarkers; Chemical Warfare Agents; Chlorambucil; Guidelines as Topic; Humans; Irritants; Keratinocytes; Langerhans Cells; Mechlorethamine; Mustard Gas; Risk Assessment; Skin; Skin Irritancy Tests

2019
DNA damage signaling in the cellular responses to mustard vesicants.
    Toxicology letters, 2020, Jun-15, Volume: 326

    Topics: Cell Survival; DNA Damage; Humans; Mechlorethamine; Mustard Gas; Mustard Plant; Signal Transduction

2020
Mast Cells Promote Nitrogen Mustard-Mediated Toxicity in the Lung Associated With Proinflammatory Cytokine and Bioactive Lipid Mediator Production.
    Toxicological sciences : an official journal of the Society of Toxicology, 2021, 10-27, Volume: 184, Issue:1

    Topics: Animals; Chemical Warfare Agents; Cytokines; Lipids; Lung; Mast Cells; Mechlorethamine; Mice; Mice, Inbred C57BL; Mustard Gas

2021
Supporting discovery and development of medical countermeasures for chemical injury to eye and skin.
    Experimental eye research, 2022, Volume: 221

    Topics: Burns, Chemical; Chemical Warfare Agents; Humans; Mechlorethamine; Medical Countermeasures; Mustard Gas; Skin; United States

2022
Therapeutic Potential of Mesenchymal Stem Cell-Secreted Factors on Delay in Corneal Wound Healing by Nitrogen Mustard.
    International journal of molecular sciences, 2022, Sep-29, Volume: 23, Issue:19

    Topics: Animals; Corneal Injuries; Culture Media, Conditioned; Endothelial Cells; Mechlorethamine; Mesenchymal Stem Cells; Mice; Mustard Gas; Reactive Oxygen Species; Stem Cell Factor; Swine; Wound Healing

2022
A corneo-retinal hypercitrullination axis underlies ocular injury to nitrogen mustard.
    Experimental eye research, 2023, Volume: 231

    Topics: Animals; Cornea; Eye Injuries; Gliosis; Irritants; Mechlorethamine; Mice; Mustard Gas; Retina; Retinal Diseases

2023
Mustard Gas Exposure Actuates SMAD2/3 Signaling to Promote Myofibroblast Generation in the Cornea.
    Cells, 2023, 06-02, Volume: 12, Issue:11

    Topics: Animals; Chemical Warfare Agents; Cornea; Humans; Mechlorethamine; Mustard Gas; Myofibroblasts; Rabbits; Signal Transduction; Smad2 Protein

2023
Cellular senescence implication in mustard keratopathy.
    Experimental eye research, 2023, Volume: 233

    Topics: Animals; Cellular Senescence; Chemical Warfare Agents; Cornea; Corneal Diseases; Humans; Mechlorethamine; Mice; Mustard Gas

2023
Insights into mustard gas keratopathy- characterizing corneal layer-specific changes in mice exposed to nitrogen mustard.
    Experimental eye research, 2023, Volume: 236

    Topics: Animals; Cornea; Corneal Diseases; Corneal Edema; Corneal Ulcer; Humans; Mechlorethamine; Mice; Microscopy, Confocal; Mustard Gas; Vision Disorders

2023