mechlorethamine has been researched along with melphalan in 161 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 109 (67.70) | 18.7374 |
1990's | 29 (18.01) | 18.2507 |
2000's | 12 (7.45) | 29.6817 |
2010's | 11 (6.83) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Hansch, C; Khwaja, TA; Selassie, CD | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Balzarini, J; Das, U; De Clercq, E; Dimmock, JR; Hashimoto, K; Kawase, M; Pati, HN; Sakagami, H | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Ames, BN; Baker, MS; Benedict, WF; Choi, E; Haroun, L | 1 |
Furno, F; Giovanelli, E; Locatelli, F; Neretto, G; Pellerito, R | 1 |
Sieber, SM | 1 |
Glatstein, E; Hoppe, RT; Kaplan, HS; Portlock, CS; Rosenberg, SA | 1 |
Bruntsch, U; Gallmeier, WM | 1 |
Brody, JI | 1 |
Filipski, J; Kohn, KW; Zwelling, LA | 1 |
Lewensohn, R; Ringborg, U | 2 |
Morley, AA; Seshadri, RS; Trainor, KJ | 1 |
Ewig, RA; Kohn, KW; Ross, WE | 1 |
Merriman, RL; Sladek, NE | 1 |
Kornfeld, S; Minnich, V; Smith, ME; Thompson, D | 1 |
Bergsagel, DE; Pruzanski, W | 1 |
Goldenberg, GJ | 1 |
Kahn, SB | 1 |
Carter, RD; Krementz, ET | 1 |
Alaoui-Jamali, MA; Batist, G; Centurioni, GM; Lehnert, S; Panasci, L; Schecter, R | 1 |
Bauer, GB; Bennett, RA; Povirk, LF; Wang, P | 1 |
Caravelli, J; Chapman, D; Clarkson, BD; Gaynor, JJ; Merke, DP; Myers, J; Straus, DJ; Yahalom, J | 1 |
Bastion, Y; Coiffier, B; Tigaud, JD | 1 |
Deutsch, WA; Erickson, LC; Futscher, BW; Grabowski, DT; Kelley, MR; Pieper, RO | 1 |
Edgren, M; Fichtinger-Schepman, AM; Hansson, J; Ringborg, U | 1 |
Bernard, GS; Hobbs, ML; Mellard, DN; Meyn, RE; Murray, D; vanAnkeren, SC | 1 |
Caldecott, K; Jeggo, P | 1 |
Petru, E; Schmähl, D | 1 |
Erickson, LC; Futscher, BW | 1 |
Erickson, LC; Pieper, RO | 1 |
Kohn, KW; O'Connor, PM | 1 |
Jestrimski, KW; Lowenthal, RM | 1 |
Koziner, B; Zori Comba, A | 1 |
Straus, DJ | 1 |
Caravelli, J; Chapman, D; Clarkson, BD; Gaynor, J; Lee, BJ; Merke, D; Myers, J; Nisce, LZ; Straus, DJ | 1 |
Erickson, LC; Futscher, BW; Pieper, RO | 1 |
Cantrell, JE; Green, D; Schein, PS | 1 |
Hansson, J; Lewensohn, R; Nilsson, B; Ringborg, U | 1 |
Dean, SW; Green, D; McPherson, E; Schein, PS | 1 |
Hartley, JA; Kohn, KW; Mattes, WB | 1 |
Lehner, T; Rosenoer, VM; Smith, J | 1 |
Leĭkina, FI; Smolianskaia, AZ | 1 |
Bradley, SG; Munson, AE; Rose, WC | 1 |
Everett, J | 1 |
Du Priest, RW; Fletcher, WS | 1 |
Rutledge, F; Smith, JP | 1 |
Damnavits, J; Goepfert, H; Rochlin, DB | 1 |
Donelli, MG; Garattini, S; Rosso, R | 1 |
Frei, E; Goldin, A; Schabel, FM | 1 |
Tolen, SJ; Valeriote, FA | 1 |
Krementz, ET; Ryan, RF | 1 |
Greenwald, ES | 1 |
Pavone-Macaluso, M | 1 |
Bergsagel, DE; McCulloch, EA; Ogawa, M | 1 |
Gschwind, C; Hersh, EM; McBride, CM | 1 |
Iamshanov, VA; Kraĭz, BO; Petrov, AS | 1 |
Astrakhan, VI; Bychkov, MB; Garin, AM; Vvedenskaia, NA | 1 |
Burns, BC; Rutledge, F; Smith, JP; Soffar, S | 1 |
Mahaley, MS; Woodhall, B | 1 |
Edwards, AJ; Rowland, GF | 2 |
Fomina, IP; Navashin, SM; Terent'eva, TG | 1 |
Smirnova, IN | 1 |
Cheliapov, NV; Doronina, TN; Gorin, AI; Tseĭtlin, PI | 1 |
McBride, CM | 1 |
Bihler, I; Goldenberg, GJ; Iise, D; Israels, LG; Vanstone, CL | 1 |
Fennelly, JJ | 1 |
Lelieveld, P; van Putten, LM | 1 |
Bishop, RC | 1 |
Eridani, S; Ponti, GB; Tiso, R; Valentini, R | 1 |
Griffin, AC; Klatt, O; McBride, C; Stehlin, JS | 1 |
Unger, E | 1 |
Kumkumadzhian, VA; Papoian, SA | 1 |
Williamson, CE; Witten, B | 1 |
Dill, PL; Macaluso, CK; Marsden, JA; Weisenthal, LM | 1 |
Clarkson, BD; Koziner, B; Lee, BJ; Myers, J; Straus, DJ | 1 |
Arlin, Z; Gee, T; Kempin, S; Koziner, B; Lee, BJ; McCormick, B; Mertelsmann, R; Myers, J; Nisce, LZ; Straus, DJ | 1 |
Culo, F; Spellman, JM; Yuhas, JM | 1 |
Arrick, BA; Nathan, CF | 1 |
Cornbleet, MA; Leonard, RC; Smyth, JF | 1 |
Collins, FG; Skibba, JL | 2 |
Bergfeld, WF; Guirguis, MN; Hanke, CW; Lewis, LJ | 1 |
Aigner, K; Schwemmle, K | 1 |
Parsons, PG | 1 |
Dantas, ME; Glode, LM; Koeppler, H; Morton, N; Robinson, WA; Sutherland, J; Thomas, MR | 1 |
Aigner, K; Hild, P; Hundeiker, M | 1 |
Benckhuysen, C; van der Steen, J; van Wichen, BH | 1 |
Adams, GE; Horsman, MR; Kandaiya, S; Rajaratnam, S; Smith, E; Stratford, IJ; Williamson, C | 1 |
Naujokaitis, SA | 1 |
Lomova, TIu; Shakhova, IK; Shkodinskaia, EN | 1 |
Horton, JK; Srivastava, DK; Wilson, SH; Zmudzka, BZ | 1 |
Alessandrino, EP; Astori, C; Bernasconi, P; Brusamolino, E; Canevari, A; Castelli, G; Lazzarino, M; Morra, E; Orlandi, E; Pagnucco, G | 1 |
Povirk, LF; Shuker, DE | 1 |
Behar, RA; Hoppe, RT; Horning, SJ | 1 |
Brice, P; Castaigne, S; Gisselbrecht, C; Marolleau, JP; Pautier, P | 1 |
Carter, RD; Creech, O; Krementz, ET; Muchmore, JH; Ryan, RF; Sutherland, CM | 1 |
Alaoui-Jamali, MA; Batist, G; Fahl, WE; Schecter, RL; Woo, A | 1 |
Callery, PS; Egorin, MJ; Eiseman, JL; Hu, LT; Li, Y; Pan, SS; Rogers, FA; Sentz, DL | 1 |
Doi, T; Nagai, H; Suzuki, T; Tsukuda, R | 1 |
Laval, J; Lee, CS; Mattes, WB; O'Connor, TR | 1 |
Demers, GW; Galloway, DA; Hawkins, DS | 1 |
Luedtke, NW; Millard, JT; Spencer, RJ | 1 |
Bauer, GB; Povirk, LF | 1 |
Hopkins, PB; Millard, JT; Spencer, RJ | 1 |
Bass, G; Bloxham, D; Gandhi, MK; Jestice, K; Marcus, RE; Scott, MA | 1 |
Devereux, S; Goldstone, AH; Gregory, W; Hancock, B; Harrison, CN; Hoskin, P; Hudson, GV; Linch, DC; MacMillan, AK; Milligan, D; Newland, AC; Winfield, D | 1 |
Fenselau, C; Szilágyi, Z | 1 |
Ara, G; Bunnell, C; Elias, A; Frei, E; Richardson, P; Teicher, B; Tew, K; Wheeler, C | 1 |
Calsou, P; Muller, C; Salles, B | 1 |
Beauséjour, CM; Cournoyer, D; Delisle, JS; Létourneau, S; Momparler, RL; Palerme, JS | 1 |
Angrilli, F; Ascari, E; Bertè, R; Broglia, C; Cavanna, L; Di Renzo, N; Ghirardelli, ML; Gobbi, PG; Iannitto, E; Molica, S; Petrilli, MP | 1 |
Avigdor, A; Ben-Bassat, I; Grotto, I; Hardan, I; Raanani, P; Shpilberg, O | 1 |
Hulst, AG; Jansen, R; Noort, D | 1 |
LUCK, JM | 2 |
CASTELLANO, M; LOVISETTO, P | 1 |
TRUSHEIKINA, VI | 1 |
GALTON, DA; PAPAC, R; TILL, M; WILTSHAW, E | 1 |
ALTENBURG, E; ALTENBURG, LS | 1 |
KHOMCHENOVSKII, EI | 2 |
SPASSKAIA, IG | 1 |
NOVIKOVA, MA | 1 |
IAKOVLEV, AM; KRASOVSKII, II | 1 |
DAVYDOVA, SIa; SAPOZHNIKOVA, MB | 1 |
SYRKIN, AB | 1 |
VIAZOVA, OI | 1 |
ARIEL, IM; PACK, GT | 1 |
DIDDLE, AW; JENKINS, HH; WATTS, G; WATTS, J | 1 |
BURKITT, D; CLIFFORD, P; OETTGEN, HF | 1 |
KUKRAL, JC; PRESTON, FW; STALEY, CJ | 1 |
AIZENMAN, BIu; BREDIKHINA, AM; KINRIANOVA, OA; MANDRYK, TP; SHVAIGER, MO | 1 |
ERIDANI, S; TAGLIORETTI, D; TESTERO, S; TISO, R | 1 |
GYERGYAY, F; KREPSZ, I; PUPP, A | 1 |
IGLESIAS, F; KOKAME, GM; KREMENTZ, ET | 1 |
CREECH, O; KREMENTZ, ET | 1 |
BECKERLING, C; DURR, MH; MARCHAND, P; PLESSISL, DU | 1 |
KNOCK, FE | 1 |
CHUMAKOV, VM; SYRKIN, AB | 1 |
NORIN, T | 1 |
LEBRUN, J; SMETS, W | 1 |
PARKER, RT; SHINGLETON, WW | 1 |
FITZGERALD, P; MCCARTHY, JJ; O'MALLEY, E | 1 |
HU, CC; KU, KY; LU, KH | 1 |
Balcome, S; Hafner, L; Park, S; Phillips, L; Quirk Dorr, DR; Tretyakova, N | 1 |
Angelucci, E; Baldini, L; Bordonaro, R; Broglia, C; Cavanna, L; Chisesi, T; Deliliers, GL; Federico, M; Gobbi, PG; Levis, A; Liberati, M; Merli, F; Pavone, V; Santini, G; Stelitano, C; Vitolo, U | 1 |
Diehl, V; Evens, AM; Hutchings, M | 1 |
García-Sanz, R; González-López, TJ; Graciani, IF; Hermida, G; San Miguel, JF; Vázquez, L | 1 |
Kuruvilla, J | 1 |
Brenner, C; Gallerne, C; Lemaire, C; Sharaf el dein, O | 1 |
Baik, MH; Polavarapu, A; Stillabower, JA; Stubblefield, SG; Taylor, WM | 1 |
Advani, RH; Balise, R; Greenberg, PL; Hoppe, RT; Horning, SJ; Koontz, MZ; Rosenberg, SA | 1 |
Back, AR; Lee, J; Phillips, JC; Schleis, SE; Smith, AN; Smrkovski, OA | 1 |
HSU, TC; STUBBLEFIELD, E | 1 |
Nagai, H | 1 |
Garman, B; Glickson, JD; Leeper, DB; Nath, K; Nathanson, KL; Nelson, DS; Putt, ME | 1 |
Martin, OA; Price, J | 1 |
15 review(s) available for mechlorethamine and melphalan
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The action of antitumor agents: a double-edged sword?
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Azathioprine; Burkitt Lymphoma; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; Hodgkin Disease; Humans; Immunosuppressive Agents; Kidney Neoplasms; Leukemia, Myeloid, Acute; Lymphoma; Mechlorethamine; Melphalan; Mercaptopurine; Methotrexate; Mice; Multiple Myeloma; Neoplasms; Prednisone; Pregnancy; Procarbazine; Time Factors; Vincristine | 1977 |
[Treatment of relapses and failures in disseminated Hodgkin's disease].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplantation; Carmustine; Cisplatin; Cyclophosphamide; Cytarabine; Dacarbazine; Doxorubicin; Epirubicin; Etoposide; Hodgkin Disease; Humans; Ifosfamide; Mechlorethamine; Melphalan; Methotrexate; Mitoguazone; Prednisone; Procarbazine; Remission Induction; Transplantation, Autologous; Transplantation, Homologous; Vinblastine; Vincristine | 1991 |
Cytotoxic chemotherapy-induced second primary neoplasms: clinical aspects.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Hodgkin Disease; Humans; Leukemia; Mechlorethamine; Melphalan; Neoplasms, Multiple Primary; Ovarian Neoplasms; Prednisone; Procarbazine; Randomized Controlled Trials as Topic; Retrospective Studies; Vincristine | 1991 |
Corticosteroid drugs: their role in oncological practice.
Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms; Cyclophosphamide; Dacarbazine; Doxorubicin; Drug Therapy, Combination; Dyspnea; Fluorouracil; Hodgkin Disease; Humans; Hypercalcemia; Leukemia; Leukemia, Lymphoid; Lymphoma; Mechlorethamine; Melphalan; Methotrexate; Multiple Myeloma; Palliative Care; Prednisone; Procarbazine; Receptors, Glucocorticoid; Vinblastine; Vincristine; Vomiting | 1986 |
[Rescue treatment in Hodgkin's disease].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Hodgkin Disease; Humans; Lomustine; Mechlorethamine; Melphalan; Prednisone; Procarbazine; Vinblastine; Vincristine; Vindesine | 1987 |
Treatment of advanced Hodgkin's disease.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Combined Modality Therapy; Dacarbazine; Doxorubicin; Female; Hodgkin Disease; Humans; Leukemia; Lomustine; Lymphoma; Male; Mechlorethamine; Melphalan; Middle Aged; Neoplasms, Multiple Primary; Prednisone; Procarbazine; Remission Induction; Vinblastine; Vincristine; Vindesine | 1989 |
Cancer chemotherapy. I.
Topics: Animals; Busulfan; Chlorambucil; Cyclophosphamide; Female; Humans; Male; Mechlorethamine; Melphalan; Methotrexate; Mice; Neoplasms; Thiotepa | 1972 |
Glutathione metabolism as a determinant of therapeutic efficacy: a review.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Biological Transport; Carmustine; Cyclophosphamide; Cytochrome P-450 Enzyme System; Glutathione; Humans; Mechlorethamine; Melphalan; Mercaptopurine; Mice; Neoplasms; Neoplasms, Experimental | 1984 |
High-dose alkylating agent therapy: a review of clinical experiences.
Topics: Alkylating Agents; Busulfan; Carcinoma, Bronchogenic; Carmustine; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Male; Mechlorethamine; Melphalan; Neoplasms; Ovarian Neoplasms; Testicular Neoplasms | 1984 |
DNA damage and mutagenesis induced by nitrogen mustards.
Topics: Animals; Base Sequence; Chlorambucil; Cyclophosphamide; DNA; DNA Damage; DNA Repair; Humans; Mechlorethamine; Melphalan; Molecular Sequence Data; Mutagenesis; Nitrogen Mustard Compounds; Phosphoramide Mustards | 1994 |
NEWER ANTICANCER AGENTS.
Topics: Alkylating Agents; Antineoplastic Agents; Arsenicals; Cyclophosphamide; Dactinomycin; Fluorouracil; Humans; Mechlorethamine; Melphalan; Methotrexate; Mitomycin; Mitomycins; Neoplasms; Pharmacology; Steroids; Triethylenemelamine; Vinblastine; Vincristine | 1964 |
Treatment of Hodgkin lymphoma: the past, present, and future.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials, Phase III as Topic; Cyclophosphamide; Dacarbazine; Disease-Free Survival; Doxorubicin; Etoposide; Hodgkin Disease; Humans; Lomustine; Mechlorethamine; Melphalan; Multicenter Studies as Topic; Neoplasm Staging; Prednisone; Procarbazine; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Vinblastine; Vincristine; Vindesine | 2008 |
Standard therapy of advanced Hodgkin lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dacarbazine; Dexamethasone; Disease-Free Survival; Doxorubicin; Etoposide; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Mechlorethamine; Melphalan; Methylprednisolone; Positron-Emission Tomography; Prednisone; Procarbazine; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Salvage Therapy; Transplantation, Autologous; Treatment Outcome; Vinblastine; Vincristine; Vindesine | 2009 |
[Treatment strategy of Hodgkin lymphoma].
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brentuximab Vedotin; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dacarbazine; Dexamethasone; Doxorubicin; Etoposide; Hodgkin Disease; Humans; Immunoconjugates; Mechlorethamine; Melphalan; Molecular Targeted Therapy; Neoplasm Recurrence, Local; Positron-Emission Tomography; Prednisone; Procarbazine; Prognosis; Radiotherapy, Adjuvant; Rituximab; Vinblastine; Vincristine | 2014 |
7 trial(s) available for mechlorethamine and melphalan
Article | Year |
---|---|
Alternating chemotherapy and irradiation in the treatment of advanced Hodgkin's disease.
Topics: Adolescent; Adult; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Male; Mechlorethamine; Melphalan; Middle Aged; Prednisone; Procarbazine; Remission, Spontaneous; Vinblastine; Vincristine | 1979 |
Prognostic factors among 185 adults with newly diagnosed advanced Hodgkin's disease treated with alternating potentially noncross-resistant chemotherapy and intermediate-dose radiation therapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Female; Hematocrit; Hodgkin Disease; Humans; Lomustine; Lymphatic Metastasis; Male; Mechlorethamine; Melphalan; Middle Aged; Models, Biological; Neoplasm Staging; Prednisone; Procarbazine; Prognosis; Remission Induction; Survival Analysis; Vinblastine; Vincristine; Vindesine | 1990 |
Treatment of advanced Hodgkin's disease.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Combined Modality Therapy; Dacarbazine; Doxorubicin; Female; Hodgkin Disease; Humans; Leukemia; Lomustine; Lymphoma; Male; Mechlorethamine; Melphalan; Middle Aged; Neoplasms, Multiple Primary; Prednisone; Procarbazine; Remission Induction; Vinblastine; Vincristine; Vindesine | 1989 |
Results and prognostic factors following optimal treatment of advanced Hodgkin's disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Dacarbazine; Doxorubicin; Hodgkin Disease; Humans; Lomustine; Mechlorethamine; Melphalan; Middle Aged; Prednisone; Procarbazine; Randomized Controlled Trials as Topic; Vinblastine; Vincristine; Vindesine | 1989 |
Treatment of advanced Hodgkin's disease with chemotherapy and irradiation. Controlled trial of two versus three alternating, potentially non-cross-resistant drug combinations.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Combined Modality Therapy; Dacarbazine; Doxorubicin; Female; Hodgkin Disease; Humans; Lomustine; Male; Mechlorethamine; Melphalan; Middle Aged; Prednisone; Procarbazine; Vinblastine; Vincristine; Vindesine | 1984 |
Lomustine and melphalan cannot be replaced by cyclophosphamide and etoposide without reducing efficacy in MOPPEBVCAD chemotherapy for advanced Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Epirubicin; Etoposide; Female; Hodgkin Disease; Humans; Lomustine; Male; Mechlorethamine; Melphalan; Middle Aged; Prednisone; Procarbazine; Prospective Studies; Treatment Outcome; Vinblastine; Vincristine; Vindesine | 2000 |
ABVD versus modified stanford V versus MOPPEBVCAD with optional and limited radiotherapy in intermediate- and advanced-stage Hodgkin's lymphoma: final results of a multicenter randomized trial by the Intergruppo Italiano Linfomi.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Dacarbazine; Disease-Free Survival; Doxorubicin; Etoposide; Female; Hodgkin Disease; Humans; Lomustine; Male; Mechlorethamine; Melphalan; Middle Aged; Prednisone; Procarbazine; Treatment Outcome; Vinblastine; Vincristine; Vindesine | 2005 |
140 other study(ies) available for mechlorethamine and melphalan
Article | Year |
---|---|
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
3,5-Bis(benzylidene)-1-[3-(2-hydroxyethylthio)propanoyl]piperidin-4-ones: a novel cluster of potent tumor-selective cytotoxins.
Topics: Animals; Benzylidene Compounds; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Mice; Piperidines; Structure-Activity Relationship; Sulfides | 2011 |
Mutagenicity of cancer chemotherapeutic agents in the Salmonella/microsome test.
Topics: 2-Naphthylamine; Animals; Antineoplastic Agents; Carcinogens; Cisplatin; Cyclophosphamide; Daunorubicin; Doxorubicin; Drug Evaluation, Preclinical; Hycanthone; Ifosfamide; In Vitro Techniques; Male; Mechlorethamine; Melphalan; Mercaptopurine; Mesylates; Microsomes, Liver; Mutagens; Nitrogen Mustard Compounds; Propylamines; Rats; Salmonella typhimurium; Thiotepa; Tilorone; Uracil Mustard | 1977 |
[Survival and therapy of multiple myeloma. Apropos of 56 observed cases].
Topics: Adrenocorticotropic Hormone; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Male; Mechlorethamine; Melphalan; Middle Aged; Multiple Myeloma; Prednisone; Prognosis; Vincristine | 1979 |
[Chemotherapy of the ovarian carcinoma (author's transl)].
Topics: Altretamine; Antineoplastic Agents; Chlorambucil; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hydroxyprogesterones; Mechlorethamine; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Nitrosourea Compounds; Ovarian Neoplasms; Thiotepa; Vinblastine; Vincristine | 1977 |
In vitro effects of single alkylating agents on normal peripheral blood lymphocytes.
Topics: Adult; Cell Membrane Permeability; DNA; Erythrosine; Female; Humans; Lectins; Lymphocyte Activation; Lymphocytes; Male; Mechlorethamine; Melphalan; Pokeweed Mitogens; Protein Biosynthesis; RNA | 1979 |
Effect of thiourea on survival and DNA cross-link formation in cells treated with platinum(II) complexes, L-phenylalanine mustard, and bis(2-chloroethyl)methylamine.
Topics: Animals; Cell Survival; Cells, Cultured; Cisplatin; Cross-Linking Reagents; DNA, Neoplasm; Leukemia L1210; Mechlorethamine; Melphalan; Mice; Thiourea | 1979 |
Induction of unscheduled DNA synthesis in human bone marrow cells by bifunctional alkylating agents.
Topics: Alkylating Agents; Autoradiography; Bone Marrow; Cell Differentiation; DNA; Dose-Response Relationship, Drug; Humans; Mechlorethamine; Melphalan; Thymidine; Time Factors | 1979 |
Residual marrow injury following cytotoxic drugs.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Chlorambucil; Dacarbazine; Doxorubicin; Female; Granulocytes; Hematopoietic Stem Cells; Mechlorethamine; Melphalan; Mice; Mice, Inbred BALB C; Mitomycins | 1979 |
Differences between melphalan and nitrogen mustard in the formation and removal of DNA cross-links.
Topics: Animals; Cell Survival; Cells, Cultured; DNA Repair; DNA, Neoplasm; DNA, Single-Stranded; Leukemia L1210; Mechlorethamine; Melphalan; Time Factors; X-Rays | 1978 |
Cytotoxic activity of mechlorethamine and melphalan against cultured tumor cells: potentiation by caffeine.
Topics: Animals; Antineoplastic Agents; Caffeine; Carcinoma 256, Walker; Cells, Cultured; Drug Synergism; Lymphoma; Mechlorethamine; Melphalan; Rats; Time Factors | 1978 |
Detection of mutagenic activity in human urine using mutant strains of Salmonella typhimurium.
Topics: Antineoplastic Agents; Biological Assay; Cyclophosphamide; Ethylnitrosourea; Fluorouracil; Humans; Mechlorethamine; Melphalan; Metronidazole; Mitomycins; Mutagens; Neoplasms; Salmonella typhimurium | 1976 |
Treatment of plasma cell myeloma with cytotoxic agents.
Topics: Acute Disease; Alkylating Agents; Bence Jones Protein; Bone Neoplasms; Carmustine; Cell Count; Cyclophosphamide; Drug Therapy, Combination; Humans; Immunoglobulin kappa-Chains; Immunoglobulin lambda-Chains; Mechlorethamine; Melphalan; Multiple Myeloma; Myeloma Proteins; Prednisone; Remission, Spontaneous; Time Factors | 1975 |
The role of drug transport in resistance to nitrogen mustard and other alkylating agents in L518Y lymphoblsts.
Topics: Alkylating Agents; Animals; Binding, Competitive; Biological Transport; Carmustine; Cell Line; Chlorambucil; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Resistance; Female; Leukemia, Experimental; Leukemia, Lymphoid; Male; Mechlorethamine; Melphalan; Mice; Mice, Inbred DBA; Mitomycins | 1975 |
Unusual toxicities from cancer and immunosuppressive therapy.
Topics: Antimetabolites; Antineoplastic Agents; Carcinogens; Chromosomes; Depression, Chemical; DNA, Neoplasm; Humans; Immunosuppressive Agents; Mechlorethamine; Melphalan; Mutagens | 1975 |
Chemotherapy of rhabdomyosarcoma by regional perfusion: a case report.
Topics: Adjuvants, Pharmaceutic; Chemotherapy, Cancer, Regional Perfusion; Dactinomycin; Female; Humans; Infant; Leg; Mechlorethamine; Melphalan; Rhabdomyosarcoma | 1976 |
Nitrogen mustard-DNA interaction in melphalan-resistant mammary carcinoma cells with elevated intracellular glutathione and glutathione-S-transferase activity.
Topics: Animals; Buthionine Sulfoximine; Cell Division; Cell Survival; Chlorambucil; DNA; Drug Interactions; Drug Resistance; Glutathione; Glutathione Transferase; Mammary Neoplasms, Experimental; Mechlorethamine; Melphalan; Methionine Sulfoximine; Rats; RNA, Messenger; Tumor Cells, Cultured | 1992 |
Thermolabile adenine adducts and A.T base pair substitutions induced by nitrogen mustard analogues in an SV40-based shuttle plasmid.
Topics: Adenine Nucleotides; Alkylating Agents; Base Composition; Base Sequence; Chlorambucil; Genetic Vectors; Hot Temperature; Mechlorethamine; Melphalan; Molecular Sequence Data; Mutagenesis; Plasmids; Simian virus 40; Thymine Nucleotides | 1991 |
Expression of ribosomal phosphoprotein PO is induced by antitumor agents and increased in Mer- human tumor cell lines.
Topics: Antineoplastic Agents; Blotting, Northern; Blotting, Southern; Cyclophosphamide; DNA Probes; DNA Repair; Electrophoresis, Agar Gel; Gene Expression; Humans; Mechlorethamine; Melphalan; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Phosphoproteins; Ribosomal Proteins; Tumor Cells, Cultured | 1992 |
Comparative study of two human melanoma cell lines with different sensitivities to mustine and cisplatin.
Topics: Cell Line; Cell Survival; Cisplatin; DNA, Neoplasm; Glutathione; Humans; Mechlorethamine; Melanoma; Melphalan; Platinum; Tumor Cells, Cultured | 1991 |
Isolation and characterization of nitrogen mustard-sensitive mutants of Chinese hamster ovary cells.
Topics: Aminacrine; Animals; Cells, Cultured; Cisplatin; Cricetinae; Cross Reactions; DNA; Dose-Response Relationship, Drug; Female; Gamma Rays; In Vitro Techniques; Mechlorethamine; Melphalan; Mitomycin; Mitomycins; Mutagens; Mutation; Nitrogen Mustard Compounds | 1991 |
Cross-sensitivity of gamma-ray-sensitive hamster mutants to cross-linking agents.
Topics: Animals; Camptothecin; Cell Line; Cell Survival; CHO Cells; Cisplatin; Cricetinae; Cricetulus; Cross-Linking Reagents; DNA Damage; Female; Guinea Pigs; Mechlorethamine; Melphalan; Mitomycin; Mutation; Radiation Tolerance; Ultraviolet Rays | 1991 |
Changes in c-myc and c-fos expression in a human tumor cell line following exposure to bifunctional alkylating agents.
Topics: Blotting, Northern; Cell Line; Colonic Neoplasms; Gene Expression; Humans; Kinetics; Mechlorethamine; Melphalan; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; RNA, Messenger; Transcription, Genetic | 1990 |
DNA adenine adducts induced by nitrogen mustards and their role in transcription termination in vitro.
Topics: Amino Acid Sequence; Chlorambucil; DNA; DNA Damage; Genes, myc; Mechlorethamine; Melphalan; Molecular Sequence Data; Templates, Genetic; Transcription, Genetic | 1990 |
Comparative pharmacokinetics of DNA lesion formation and removal following treatment of L1210 cells with nitrogen mustards.
Topics: Animals; Colony-Forming Units Assay; Computer Simulation; Crossing Over, Genetic; DNA Damage; In Vitro Techniques; Leukemia L1210; Mechlorethamine; Melphalan; Mice; Nitrogen Mustard Compounds; Quinacrine Mustard; Uracil Mustard | 1990 |
Transcription-terminating lesions induced by bifunctional alkylating agents in vitro.
Topics: Alkylating Agents; Alkylation; Base Sequence; Chlorambucil; Cyclophosphamide; DNA; DNA Damage; Exons; Genetic Vectors; Guanine; Humans; Mechlorethamine; Melphalan; Molecular Sequence Data; Plasmids; Proto-Oncogenes; Templates, Genetic; Transcription, Genetic | 1989 |
Antitumor activity and bone marrow toxicity of aminoglucose mustard anticancer agents in mice.
Topics: Amino Sugars; Animals; Antineoplastic Agents; Blood Glucose; Bone Marrow; DNA; Leukemia P388; Leukemia, Experimental; Leukocyte Count; Male; Mechlorethamine; Melphalan; Mice; Nitrogen Mustard Compounds; Streptozocin; Structure-Activity Relationship | 1986 |
Formation and removal of DNA cross-links induced by melphalan and nitrogen mustard in relation to drug-induced cytotoxicity in human melanoma cells.
Topics: Cell Line; Cell Survival; DNA; Humans; Mathematics; Mechlorethamine; Melanoma; Melphalan; Neoplastic Stem Cells | 1987 |
6-[Bis(2-chloroethyl)amino]-6-deoxygalactopyranose hydrochloride (C6-galactose mustard), a new alkylating agent with reduced bone marrow toxicity.
Topics: Animals; Bone Marrow; DNA Replication; Drug Evaluation, Preclinical; Female; Galactosamine; Hematopoietic Stem Cells; Leukemia P388; Leukemia, Experimental; Leukopenia; Male; Mechlorethamine; Melphalan; Mice; Mice, Inbred DBA; Neutrophils; Structure-Activity Relationship | 1987 |
DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards.
Topics: Alkylation; Base Sequence; Densitometry; DNA, Viral; Formates; Guanine; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Quinacrine Mustard; Structure-Activity Relationship; Substrate Specificity; Sulfuric Acid Esters; T-Phages; Uracil Mustard | 1986 |
Amyloidosis in mice bearing a transplantable plasma cell tumour.
Topics: Amyloidosis; Animals; Cortisone; Diet; Electrophoresis; gamma-Globulins; Mechlorethamine; Melphalan; Mice; Microscopy, Electron; Multiple Myeloma; Neoplasm Transplantation; Neoplasms, Experimental; Plasmacytoma | 1967 |
[Detection of a moderate staphylococcal phage by means of antineoplastic agents].
Topics: Aminopterin; Antibiotics, Antineoplastic; Anticholesteremic Agents; Antimetabolites; Antineoplastic Agents; Chlorambucil; Colchicine; Cyclophosphamide; Dactinomycin; Drug Resistance, Microbial; Flavonoids; Fluorouracil; Lysogeny; Mechlorethamine; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Olivomycins; Staphylococcus; Staphylococcus Phages; Thiotepa; Ultraviolet Rays; Uracil; Vinblastine; Vincristine | 1970 |
Synergistic lethal action of alkylating agents and sodium pentobarbital in the mouse.
Topics: Alkylating Agents; Animals; Atropine; Chlorambucil; Cyclophosphamide; Decamethonium Compounds; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Hexamethonium Compounds; Injections, Intraperitoneal; Injections, Intravenous; Lethal Dose 50; Male; Mechlorethamine; Melphalan; Mice; Pentobarbital; Thiotepa; Time Factors | 1974 |
Walker carcinosarcoma 256 in study of anticancer agents. II. Results.
Topics: Acetates; Animals; Antineoplastic Agents; Azirines; Benzene; Benzoates; Butyrates; Carcinoma 256, Walker; Glycine; Mannitol; Mechlorethamine; Melphalan; Niacinamide; Oxides; Phthalic Acids; Pyridines; Rats; Sulfhydryl Compounds; Toluene; Xylenes | 1966 |
Chemotherapy of testicular germinal tumors.
Topics: Alkylating Agents; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Dactinomycin; Dysgerminoma; Humans; Male; Mechlorethamine; Melphalan; Methotrexate; Nitrofurazone; Pharmaceutic Aids; Plicamycin; Prognosis; Testicular Neoplasms; Testis; Vincristine | 1973 |
Chemotherapy in the treatment of cancer of the ovary.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Cyclophosphamide; Cystadenocarcinoma; Dactinomycin; Female; Fluorouracil; Humans; Mechlorethamine; Melphalan; Ovarian Neoplasms; Thiotepa; Vinblastine | 1970 |
The effect of antihistamines in decreasing the toxicity of alkylating agents.
Topics: Alkylating Agents; Animals; Carcinoma, Ehrlich Tumor; Histamine H1 Antagonists; Mechlorethamine; Melphalan; Methyldopa; Methysergide; Mice | 1967 |
On the neurotoxic effects induced by alkylating agents.
Topics: Alanine; Animals; Anti-Bacterial Agents; Antimetabolites; Azaserine; Behavior, Animal; Central Nervous System; Chlorambucil; Cyclophosphamide; Cysteine; Drug Antagonism; Glycine; Male; Mannitol; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Phenobarbital; Phenytoin; Rats; Seizures; Spasm; Thiourea; Triethylenemelamine; Tryptophan | 1966 |
Comparative chemotherapy of AKR lymphoma and human hematological neoplasia.
Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Models, Animal; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Hodgkin Disease; Humans; Leukemia; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Mechlorethamine; Melphalan; Mice; Mice, Inbred AKR; Multiple Myeloma; Nitrosourea Compounds; Prednisone; Remission, Spontaneous; Vinblastine; Vincristine | 1974 |
Survival of hematopoietic and lymphoma colony-forming cells in vivo following the administration of a variety of alkylating agents.
Topics: Alkylating Agents; Animals; Cell Line; Cell Survival; Chlorambucil; Clone Cells; Cyclophosphamide; Female; Hematopoietic Stem Cells; Lethal Dose 50; Lymphoma; Mechlorethamine; Melphalan; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Nitrosourea Compounds; Thiotepa; Triethylenemelamine | 1972 |
Chemotherapy of melanoma of the extremities by perfusion: fourteen years clinical experience.
Topics: Adult; Aged; Arm; Chemotherapy, Cancer, Regional Perfusion; Female; Humans; Leg; Male; Mechlorethamine; Melanoma; Melphalan; Neoplasm Metastasis; Postoperative Complications; Skin Transplantation; Thiotepa | 1972 |
[Local chemotherapy of papillary neoplasms of the bladder].
Topics: Antineoplastic Agents; Cyclophosphamide; Evaluation Studies as Topic; Humans; Mechlorethamine; Melphalan; Papilloma; Peptides; Therapeutic Irrigation; Thiotepa; Triaziquone; Urinary Bladder Neoplasms | 1973 |
Chemotherapy of mouse myeloma: quantitative cell cultures predictive of response in vivo.
Topics: Animals; Antineoplastic Agents; Bone Marrow Cells; Cells, Cultured; Cyclophosphamide; Female; Fluorouracil; Mechlorethamine; Melphalan; Mice; Multiple Myeloma; Nitrosourea Compounds; Radiation Chimera; Rodent Diseases; Spleen | 1973 |
Local and systemic immunologic effects of perfusion therapy for malignant melanoma.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Dactinomycin; Extremities; Graft Rejection; Humans; Immunosuppression Therapy; Lectins; Lymphocyte Activation; Lymphocyte Depletion; Lymphocytes; Mechlorethamine; Melanoma; Melphalan; Prognosis; Streptolysins; Stress, Physiological | 1973 |
[Interaction of DNA with alkylating agents of different classes].
Topics: Alkylating Agents; DNA; Hot Temperature; Mechlorethamine; Melphalan; Nucleic Acid Denaturation; Triazines | 1973 |
[Chemotherapy in the terminal stages of tumors].
Topics: Alkylating Agents; Bone Neoplasms; Cyclophosphamide; Dysgerminoma; Lymphatic Metastasis; Lymphoma, Large B-Cell, Diffuse; Male; Mechlorethamine; Melphalan; Neoplasm Metastasis; Testicular Neoplasms | 1968 |
Systemic chemotherapy for carcinoma of the cervix.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Humans; Hydroxyurea; Mechlorethamine; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Progestins; Thiotepa; Urea; Uterine Cervical Neoplasms | 1967 |
Regional chemotherapeutic perfusion and infusion of brain and face tumors.
Topics: Adenocarcinoma; Ameloblastoma; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Ethylenediamines; Facial Neoplasms; Fibrosarcoma; Glioma; Humans; Infusions, Parenteral; Mechlorethamine; Melanoma; Melphalan; Meningioma; Methotrexate; Osteosarcoma; Perfusion; Quinones; Retinoblastoma; Rhabdomyosarcoma; Sarcoma; Thiotepa | 1967 |
Relative effects of varying concentrations of cytotoxic drugs in vitro on tumour and reticulo-endothelial tissue.
Topics: Animals; Antineoplastic Agents; DNA; DNA, Neoplasm; Fluorouracil; Glucose; In Vitro Techniques; Mammary Neoplasms, Experimental; Mechlorethamine; Melphalan; Methotrexate; Mice; Mononuclear Phagocyte System; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; RNA; RNA, Neoplasm; Spleen; Thiotepa; Tritium; Vinblastine | 1968 |
[Experimental study of the antineoplastic effect of the antibiotic polymycin].
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antifungal Agents; Antiviral Agents; Ascites; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Depression, Chemical; Injections, Intraperitoneal; Injections, Subcutaneous; Leukemia, Experimental; Mechlorethamine; Melphalan; Mice; Neoplasms, Experimental; Nitrogen Mustard Compounds; Rats; Sarcoma; Sarcoma 180; Thiotepa; Uracil | 1970 |
[Results of treatment of tonsillar tumors by olivomycin].
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Carcinoma, Squamous Cell; Chlorpromazine; Cyclophosphamide; Female; Fever; Humans; Liver Neoplasms; Lymphatic Metastasis; Lymphoma, Large B-Cell, Diffuse; Male; Mechlorethamine; Melphalan; Middle Aged; Nasopharyngeal Neoplasms; Nausea; Neoplasm Recurrence, Local; Olivomycins; Thiotepa; Thrombocytopenia; Tonsillar Neoplasms; Vomiting | 1969 |
[Effect of embichin and sarcolysin on the structure of total histone].
Topics: Animals; Cattle; Histones; Mechlorethamine; Melphalan; Optical Rotatory Dispersion; Phenylalanine; Spectrophotometry; Thymus Gland; Viscosity | 1971 |
Differential effects of nitrogen mustard, melphalan and vinblastine on the metabolism of mouse tumour and spleen slices.
Topics: Adenocarcinoma; Animals; DNA; Female; Mechlorethamine; Melphalan; Mice; Neoplasms, Experimental; Protein Biosynthesis; RNA; Spleen; Vinblastine | 1969 |
Advanced melanoma of the extremities.
Topics: Adolescent; Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Child; Dactinomycin; Female; Humans; Leg; Male; Mechlorethamine; Melanoma; Melphalan; Middle Aged; Neoplasm Metastasis; Prognosis; Skin Neoplasms | 1970 |
Evidence for a transport carrier of nitrogen mustard in nitrogen mustard-sensitive and -resistant L5178Y lymphoblasts.
Topics: Biological Transport, Active; Carbon Isotopes; Cell Line; Chlorambucil; Culture Techniques; Cyclophosphamide; Kinetics; Lymphocytes; Mechlorethamine; Melphalan; Nitrophenols; Ouabain; Protein Binding | 1970 |
Drugs and their abuse no. V--misuse of cytotoxic drugs.
Topics: Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Humans; Leukemia; Mechlorethamine; Melphalan; Methotrexate; Substance-Related Disorders; Vinblastine; Vincristine | 1971 |
Factors determining cell killing by chemotherapeutic agents in vivo. II. Melphalan, chlorambucil and nitrogen mustard.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Survival; Chlorambucil; Cyclophosphamide; DNA; Female; Hematopoietic Stem Cells; Male; Mechlorethamine; Melphalan; Mice; Spleen | 1971 |
Chemotherapy of Hodgkin's disease, lymphoma, and leukemia.
Topics: Adult; Antineoplastic Agents; Busulfan; Chlorambucil; Hodgkin Disease; Humans; Leukemia; Lymphoma; Male; Mechlorethamine; Melphalan; Vinblastine | 1968 |
Biologic effects of recent antimitotic compounds. A comparative evaluation.
Topics: Animals; Antineoplastic Agents; Chick Embryo; Colchicine; Cyclophosphamide; DNA; Fluorouracil; Humans; Hydrazines; In Vitro Techniques; Leukocytes; Mechlorethamine; Melphalan; Mitosis; Prednisolone; RNA; Triaziquone; Vinblastine; Vincristine | 1968 |
The effect of nitrogen mustard treatment on the deoxyribonucleic acid of sensitive and resistant Ehrlich tumor cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Membrane Permeability; Centrifugation, Density Gradient; DNA, Neoplasm; In Vitro Techniques; Injections, Intraperitoneal; Mechlorethamine; Melphalan; Mice; Protein Binding; Thymidine; Time Factors; Tritium | 1969 |
The effect of x-irradiation on the take and growth of the guerin-tumour. II. Histological experiments.
Topics: Animals; Mannomustine; Mechlorethamine; Melphalan; Neoplasm Transplantation; Neoplasms, Experimental; Radiation Effects; Rats | 1965 |
[Antiblastic effect of various chemotherapeutic preparations on the cells of the Ehrlich ascites tumor].
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Busulfan; Carcinoma, Ehrlich Tumor; Fluorouracil; Mechlorethamine; Melphalan; Mercaptopurine; Mice; Nitrogen Mustard Compounds; Uracil | 1966 |
Reaction mechanism of some aromatic nitrogen mustards.
Topics: Azirines; Chemical Phenomena; Chemistry; Chlorambucil; Kinetics; Mechlorethamine; Melphalan; Mercaptoethanol; Solutions | 1967 |
A novel dye exclusion method for testing in vitro chemosensitivity of human tumors.
Topics: Antineoplastic Agents; Cell Line; Cell Survival; Doxorubicin; Drug Evaluation, Preclinical; Eosine Yellowish-(YS); Etoposide; Fluorouracil; Hematoxylin; Humans; Leukemia, Myeloid, Acute; Mechlorethamine; Melphalan; Neoplasms; Staining and Labeling | 1983 |
Combination chemotherapy for the treatment of Hodgkin's disease in relapse. Results with lomustine (CCNU), melphalan (Alkeran), and vindesine (DVA) alone (CAD) and in alternation with MOPP and doxorubicin (Adriamycin), bleomycin, and vinblastine (ABV).
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Doxorubicin; Female; Hodgkin Disease; Humans; Lomustine; Male; Mechlorethamine; Melphalan; Middle Aged; Prednisone; Procarbazine; Vinblastine; Vincristine; Vindesine | 1983 |
The role of WR-2721 in radiotherapy and/or chemotherapy.
Topics: Alkylating Agents; Amifostine; Animals; Breast Neoplasms; Cyclophosphamide; Humans; In Vitro Techniques; Mechlorethamine; Melphalan; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Organothiophosphorus Compounds; Platinum; Rabbits; Radiation-Protective Agents; Rats; Time Factors | 1980 |
Altered hepatic functions and microsomal activity in perfused rat liver by hyperthermia combined with alkylating agents.
Topics: Alkylating Agents; Animals; Antipyrine; Biotransformation; Cyclophosphamide; Gluconeogenesis; Liver; Male; Mechlorethamine; Melphalan; Microsomes, Liver; Oxygen Consumption; Rats; Urea | 1983 |
Pretibial myxedema (elephantiasic form): treatment with cytotoxic therapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Humans; Leg Dermatoses; Male; Mechlorethamine; Melphalan; Methotrexate; Myxedema | 1983 |
[Technic of isolated perfusion of the extremities. Experience with 171 cases].
Topics: Arm; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Dacarbazine; Drug Therapy, Combination; Extracorporeal Circulation; Humans; Hyperthermia, Induced; Leg; Mechlorethamine; Melanoma; Melphalan; Postoperative Care; Soft Tissue Neoplasms | 1983 |
Dependence on treatment time of melphalan resistance and DNA cross-linking in human melanoma cell lines.
Topics: Caffeine; Cell Line; Cell Survival; Chlorambucil; DNA, Neoplasm; Drug Resistance; Drug Synergism; Hot Temperature; Humans; Kinetics; Mechlorethamine; Melanoma; Melphalan; Methyl Methanesulfonate; Thymidine | 1984 |
Treatment of advanced malignant melanoma with high-dose chemotherapy and autologous bone marrow transplantation. Preliminary results--Phase I study.
Topics: Adolescent; Adult; Antineoplastic Agents; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Cell Survival; Colony-Forming Units Assay; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Lymphatic Metastasis; Male; Mechlorethamine; Melanoma; Melphalan; Middle Aged; Transplantation, Autologous | 1982 |
[New modifications in isolated extremity perfusion ].
Topics: Antineoplastic Agents; Arm; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Dacarbazine; Dactinomycin; Drug Therapy, Combination; Hot Temperature; Humans; Leg; Mechlorethamine; Melanoma; Melphalan; Skin Neoplasms | 1982 |
Effects of alkylating agents on the DNA replication of cultured Yoshida sarcoma cells.
Topics: Alkylating Agents; Animals; Carmustine; Cell Division; Cell Survival; Chlorambucil; Cyclophosphamide; DNA Replication; Doxorubicin; Kinetics; Mechlorethamine; Melphalan; Mice; Sarcoma, Yoshida; Structure-Activity Relationship | 1982 |
The interaction of misonidazole with radiation, chemotherapeutic agents, or heat: a preliminary report.
Topics: Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Cisplatin; Cricetinae; Hot Temperature; Hypoxia; Mechlorethamine; Melphalan; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents | 1980 |
Thiamine protection of murine L1210 leukemia cells against mechlorethamine cytotoxicity and its relation to the choline uptake system.
Topics: Animals; Biological Transport; Choline; Leukemia L1210; Male; Mechlorethamine; Melphalan; Mice; Thiamine | 1981 |
[Repair of DNA-protein cross-links induced by antineoplastic alkylating agents].
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Cells, Cultured; Chemical Phenomena; Chemistry; Cricetinae; Cricetulus; DNA; DNA Repair; Fibroblasts; Mechlorethamine; Melphalan; Nucleoproteins | 1981 |
Induction of unscheduled DNA synthesis in human myeloma cells.
Topics: Alkylating Agents; Bone Marrow; Cell Transformation, Neoplastic; DNA; Humans; Mechlorethamine; Melphalan; Multiple Myeloma; Time Factors; Ultraviolet Rays | 1980 |
Modification of the 4-(p-nitrobenzyl) pyridine assay for measurement of melphalan and mechlorethamine in plasma.
Topics: Animals; Chromogenic Compounds; Colorimetry; Liver; Male; Mechlorethamine; Melphalan; Nitrobenzenes; Perfusion; Pyridines; Rats | 1980 |
Strategic down-regulation of DNA polymerase beta by antisense RNA sensitizes mammalian cells to specific DNA damaging agents.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cell Death; Cisplatin; DNA; DNA Damage; DNA Polymerase I; Gene Expression Regulation; Humans; Mechlorethamine; Melphalan; Methyl Methanesulfonate; Mice; RNA, Antisense; Transfection; Ultraviolet Rays; Zinc | 1995 |
Results of CAV regimen (CCNU, melphalan, and VP-16) as third-line salvage therapy for Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Drug Resistance; Etoposide; Female; Hodgkin Disease; Humans; Lomustine; Male; Mechlorethamine; Melphalan; Middle Aged; Pancytopenia; Prednisone; Procarbazine; Prospective Studies; Recurrence; Remission Induction; Salvage Therapy; Survival Rate; Vinblastine; Vincristine | 1994 |
Hodgkin's disease with bulky mediastinal involvement: effective management with combined modality therapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Dacarbazine; Doxorubicin; Female; Hodgkin Disease; Humans; Male; Mechlorethamine; Mediastinal Neoplasms; Melphalan; Middle Aged; Prednisone; Procarbazine; Radiotherapy; Radiotherapy Dosage; Survival Rate; Vinblastine; Vincristine | 1993 |
Pregnancy after autologous bone marrow transplantation for malignant lymphomas.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Cytarabine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Infant, Newborn; Lymphoma, Large B-Cell, Diffuse; Mechlorethamine; Melphalan; Podophyllotoxin; Prednisone; Pregnancy; Pregnancy Outcome; Procarbazine; Remission Induction; Salvage Therapy; Vincristine | 1994 |
Regional chemotherapy for melanoma. A 35-year experience.
Topics: Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Clinical Trials as Topic; Combined Modality Therapy; Extracorporeal Membrane Oxygenation; Female; Humans; Lymphatic Metastasis; Male; Mechlorethamine; Melanoma; Melphalan; Middle Aged; Neoplasm Recurrence, Local; Skin Neoplasms; Survival Analysis; Survival Rate; Thiotepa; Time Factors | 1994 |
Expression of a rat glutathione-S-transferase complementary DNA in rat mammary carcinoma cells: impact upon alkylator-induced toxicity.
Topics: Alkylating Agents; Animals; Biological Transport; Cell Line; Cell Nucleus; Chlorambucil; Cisplatin; DNA, Complementary; Gene Expression; Genetic Vectors; Glutathione Transferase; Macromolecular Substances; Mammary Neoplasms, Experimental; Mechlorethamine; Melphalan; Rats; RNA, Messenger; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1993 |
Synthesis and antitumor evaluation of a highly potent cytotoxic DNA cross-linking polyamine analogue, 1,12-diaziridinyl-4,9-diazadodecane.
Topics: Animals; Antineoplastic Agents; Aziridines; Cross-Linking Reagents; DNA; Electrophoresis, Agar Gel; Female; Leukemia L1210; Mechlorethamine; Melphalan; Mice; Mice, Inbred Strains; Spermine; Thiotepa | 1996 |
Dose-response relationships of cytotoxicity, PFC response and histology in the spleen in rats treated with alkylating agents.
Topics: Animals; Antineoplastic Agents, Alkylating; Body Weight; Cell Count; Cell Survival; Chlorambucil; Cyclophosphamide; Dose-Response Relationship, Drug; Hemolytic Plaque Technique; Immune System; Injections, Intravenous; Male; Mechlorethamine; Melphalan; Organ Size; Rats; Rats, Inbred F344; Sensitivity and Specificity; Spleen | 1996 |
Excision of DNA adducts of nitrogen mustards by bacterial and mammalian 3-methyladenine-DNA glycosylases.
Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; Chlorambucil; DNA Adducts; DNA Glycosylases; Escherichia coli; Guanine; Humans; Mechlorethamine; Melphalan; Molecular Sequence Data; N-Glycosyl Hydrolases; Rats | 1996 |
Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Aphidicolin; Carboplatin; Cell Cycle; Cell Line, Transformed; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cisplatin; Embryo, Mammalian; Fibroblasts; Genes, p53; Genes, Retinoblastoma; Heterozygote; Homozygote; Humans; Infant, Newborn; Kinetics; Male; Mechlorethamine; Melphalan; Mice; Oncogene Proteins, Viral; Paclitaxel; Papillomaviridae; Papillomavirus E7 Proteins; Repressor Proteins; Skin; Time Factors | 1996 |
The 5'-GNC preference for mustard cross-linking is preserved in a restriction fragment.
Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; Chlorambucil; Cross-Linking Reagents; Deoxyribonuclease EcoRI; DNA; DNA Damage; Mechlorethamine; Melphalan; Molecular Sequence Data; Nitrogen Mustard Compounds; Oligodeoxyribonucleotides; Structure-Activity Relationship; Substrate Specificity; Xenopus | 1996 |
Specificity and kinetics of interstrand and intrastrand bifunctional alkylation by nitrogen mustards at a G-G-C sequence.
Topics: Adenine Phosphoribosyltransferase; Alkylation; Animals; Base Sequence; CHO Cells; Cricetinae; DNA Damage; DNA Methylation; Kinetics; Mechlorethamine; Melphalan; Models, Molecular; Mutagenesis; Nitrogen Mustard Compounds; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Phosphoramide Mustards | 1997 |
Effect of nucleosome structure on DNA interstrand cross-linking reactions.
Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; Chlorambucil; Cross-Linking Reagents; DNA, Ribosomal; Mechlorethamine; Melphalan; Molecular Sequence Data; Nitrogen Mustard Compounds; Nucleosomes; RNA, Ribosomal, 5S; Xenopus | 1998 |
The minimum CD34 threshold depends on prior chemotherapy in autologous peripheral blood stem cell recipients.
Topics: Adolescent; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Carmustine; Combined Modality Therapy; Female; Hematologic Neoplasms; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Lomustine; Male; Mechlorethamine; Melphalan; Middle Aged; Transplantation, Autologous | 1999 |
High-dose BEAM chemotherapy with autologous haemopoietic stem cell transplantation for Hodgkin's disease is unlikely to be associated with a major increased risk of secondary MDS/AML.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Child; Child, Preschool; Chlorambucil; Cohort Studies; Combined Modality Therapy; Cytarabine; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Incidence; Infant; Leukemia, Myeloid; Life Tables; Lomustine; Male; Mechlorethamine; Melphalan; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Podophyllotoxin; Prednisolone; Prednisone; Procarbazine; Retrospective Studies; Risk; Salvage Therapy; Vinblastine; Vincristine | 1999 |
Molecular dynamics simulation of metallothionein-drug complexes.
Topics: Binding Sites; Chemical Phenomena; Chemistry, Physical; Chlorambucil; Computer Simulation; Crystallography, X-Ray; Cysteine; Mechlorethamine; Melphalan; Metallothionein; Models, Structural; Nitrogen Mustard Compounds; Protein Binding; Zinc | 2000 |
Double high-dose chemotherapy with stem cell rescue (HD-SCR) in patients with breast cancer - effect of sequence.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Breast Neoplasms; Carmustine; Cell Survival; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Hematopoietic Stem Cell Transplantation; Humans; Mechlorethamine; Melphalan; Mice; Neoplasms, Experimental; Tumor Cells, Cultured | 2000 |
The activity of the DNA-dependent protein kinase (DNA-PK) complex is determinant in the cellular response to nitrogen mustards.
Topics: Animals; Antibiotics, Antineoplastic; Antigens, Nuclear; Bleomycin; Cell Line; Cell Survival; Cross-Linking Reagents; DNA; DNA Damage; DNA Helicases; DNA-Activated Protein Kinase; DNA-Binding Proteins; Humans; Ku Autoantigen; Mechlorethamine; Melphalan; Mice; Mice, SCID; Mutation; Nitrogen Mustard Compounds; Nuclear Proteins; Protein Serine-Threonine Kinases; Transfection; Zinostatin | 2000 |
Coexpression of rat glutathione S-transferase A3 and human cytidine deaminase by a bicistronic retroviral vector confers in vitro resistance to nitrogen mustards and cytosine arabinoside in murine fibroblasts.
Topics: 3T3 Cells; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Blotting, Southern; Cell Division; Cytarabine; Cytidine Deaminase; DNA, Complementary; Drug Resistance, Neoplasm; Fibroblasts; Gene Transfer Techniques; Genetic Vectors; Glutathione Transferase; Humans; Mechlorethamine; Melphalan; Mice; Protein Biosynthesis; Rats; Retroviridae; Tetrazolium Salts; Thiazoles; Transduction, Genetic | 2000 |
[High-dose chemotherapy and autologous stem cell transplantation for refractory and relapsing Hodgkin's disease as first-line therapy-- studies at Sheba Medical Center--Tel Hashomer].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Combined Modality Therapy; Cytarabine; Dacarbazine; Doxorubicin; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Male; Mechlorethamine; Melphalan; Middle Aged; Podophyllotoxin; Prednisone; Procarbazine; Recurrence; Retrospective Studies; Survival Rate; Time Factors; Vinblastine; Vincristine | 2000 |
Covalent binding of nitrogen mustards to the cysteine-34 residue in human serum albumin.
Topics: Binding Sites; Chlorambucil; Cyclophosphamide; Cysteine; Drug Monitoring; Humans; In Vitro Techniques; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Protein Binding; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2002 |
The action of the phenylalanine mustards and of several homologs on mouse melanoma.
Topics: Animals; Mechlorethamine; Melanoma; Melphalan; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1957 |
[P-bis-(beta-chloroethyl) aminophenylalanine (sarcolysin) in antiblastic chemotherapy with special reference to lymphatic blood diseases].
Topics: Hodgkin Disease; Humans; Leukemia; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Melphalan; Multiple Myeloma; Nitrogen Mustard Compounds; Phenylalanine; Plasma Cells; Sarcoma | 1958 |
[Anti-tumor activity of optic isomers of sarcolysin].
Topics: Isomerism; Mechlorethamine; Melphalan; Neoplasms; Nitrogen Mustard Compounds; Phenylalanine | 1958 |
Preliminary clinical trial of p-di-2-chloroethyl-amino-L-phenylalanine (CB 3025, melphalan) and of di-2-chloroethyl methanesulfonate (CB 1506).
Topics: Antineoplastic Agents; Humans; Mechlorethamine; Melphalan; Mesylates; Nitrogen Mustard Compounds; Phenylalanine | 1958 |
Ratio of visible to lethal mutations produced in Drosophila by phenylalanine mustard.
Topics: Animals; Chromosomes; Drosophila; Mechlorethamine; Melphalan; Mutation; Nitrogen Mustard Compounds; Phenylalanine | 1959 |
[Mechanism of anti-tumor effects of dl-N-di-(2-chloroethyl)-aminophenylalanine (sarcolysin) and triethyleneimino-S-triazine].
Topics: Humans; Mechlorethamine; Melphalan; Neoplasms; Nitrogen Mustard Compounds; Triazines; Triethylenemelamine | 1959 |
[Combined effect of radioactive methionine and of sarcolysin on animal tumors].
Topics: Animals; Mechlorethamine; Melphalan; Methionine; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1959 |
[Distribution of sarcolysin-C14 in the body of rats with sarcoma 45 and with drug-resistant variant of this tumor].
Topics: Animals; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Rats; Sarcoma; Sarcoma, Experimental | 1961 |
[A case of prolonged remission of lymphosarcomatosis after sarcolysin and roentgen-ray therapy].
Topics: Lymphoma, Non-Hodgkin; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds | 1960 |
[Regional fractional method of administration of sarcolysin in various primary tumors].
Topics: Mechlorethamine; Melphalan; Neoplasms; Nitrogen Mustard Compounds | 1961 |
Further observations on the efficacy of phenylalanine mustards against mouse melanoma.
Topics: Animals; Mechlorethamine; Melanoma, Experimental; Melphalan; Mice; Nitrogen Mustard Compounds; Phenylalanine | 1961 |
[The effect of sarcolysin and dopan on the biosynthesis of pyrimidines of nucleic acid in transplanted tumors and tissues of the recipient organism].
Topics: Mechlorethamine; Melphalan; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nucleic Acids; Phenylalanine; Pyrimidines; Uracil Mustard | 1960 |
[Effect of aminazin and of dinitrophenol on the activity of dopan and sarcolysin].
Topics: Chlorpromazine; Dinitrophenols; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Nitrophenols; Uracil Mustard | 1960 |
[Changes of encolytic properties of the blood serum from rats bearing Guerin's carcinoma during therapy with sarcolysin].
Topics: Animals; Carcinoma; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Rats; Serum | 1959 |
Treatment of disseminated melanoma with phenylalanine mustard (melphelan) and autogenous bone marrow transplants.
Topics: Bone Marrow; Bone Marrow Transplantation; Humans; Mechlorethamine; Melanoma; Melphalan; Nitrogen Mustard Compounds | 1962 |
Nitrogen and phenylalanine mustard. Use in women with intrauterine cancer.
Topics: Female; Humans; Mechlorethamine; Melphalan; Neoplasms; Nitrogen; Nitrogen Mustard Compounds; Phenylalanine; Uterine Neoplasms | 1962 |
Malignant lymphoma involving the jaw in African children: treatment with alkylating agents and actinomycin D.
Topics: Alkylating Agents; Aziridines; Child; Cyclophosphamide; Dactinomycin; Humans; Jaw; Lymphoma; Mechlorethamine; Melphalan | 1963 |
Effect of anticancer drugs on experimental wound healing.
Topics: Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Humans; Mechlorethamine; Melphalan; Thiotepa; Wound Healing | 1962 |
[COMPARISON OF CERTAIN METHODS OF INITIAL SELECTION OF ANTINEOPLASTIC SUBSTANCES IN VITRO].
Topics: Antineoplastic Agents; In Vitro Techniques; Mechlorethamine; Melphalan; Mercaptopurine; Research; Thiotepa | 1963 |
[EVALUATION OF THE CURRENT THERAPEUTIC TRENDS IN HODGKIN'S DISEASE. CRITICAL REVIEW AND CASUISTIC CONTRIBUTION].
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Aziridines; Bone Marrow Transplantation; Colchicine; Cyclophosphamide; Dactinomycin; Hodgkin Disease; Mechlorethamine; Melphalan; Neoplasms; Radioisotopes; Radiotherapy, High-Energy; Triethylenemelamine; Vinblastine | 1963 |
[THE REDUCTION OF RADIOPHOSPHORUS 32 INCORPORATION INTO CANCER CELLS BY NONTOXIC DOSES OF CYTOSTATIC SUBSTANCES].
Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Cytostatic Agents; Mannomustine; Mechlorethamine; Melphalan; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; Phosphorus Isotopes; Radiation Injuries; Radiation Injuries, Experimental; Research; Triethylenemelamine | 1963 |
CURRENT STATUS OF CHEMOTHERAPY OF CANCER.
Topics: Alkylating Agents; Anti-Bacterial Agents; Antineoplastic Agents; Black People; Chemotherapy, Cancer, Regional Perfusion; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Dermatologic Agents; DNA; DNA, Neoplasm; Fluorouracil; Geriatrics; Humans; Mechlorethamine; Melphalan; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Pharmacology; Thiotepa; Toxicology; Triethylenemelamine; Vinblastine; Vincristine | 1964 |
REGIONAL PERFUSION IN MELANOMA OF LIMBS.
Topics: Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Extremities; Humans; Mechlorethamine; Melanoma; Melphalan; Neoplasm Metastasis; Neoplasms; Postoperative Complications; Surgical Procedures, Operative; Thiotepa; Toxicology; Wound Healing | 1964 |
EXTRACORPOREAL HYPOTHERMIA WITHOUT THORACOTOMY. AN EXPERIMENTAL STUDY IN THE USE OF COLD FOR NEUROSURGERY AND CANCERICIDAL PERFUSIONS.
Topics: Blood Flow Velocity; Body Temperature; Cardiac Surgical Procedures; Chemotherapy, Cancer, Regional Perfusion; Cold Temperature; Dogs; Electric Countershock; Electrocardiography; Femoral Artery; Heart, Artificial; Hypothermia; Hypothermia, Induced; Jugular Veins; Mechlorethamine; Melphalan; Neoplasms; Neurosurgery; Perfusion; Research; Thiotepa; Thoracic Surgery; Thoracotomy; Ventricular Fibrillation | 1964 |
INFLUENCE OF SOME ANTITUMOR DRUGS ON BODY AND ORGANS GROWTH IN RATS.
Topics: Adrenal Glands; Antineoplastic Agents; Body Weight; Bone and Bones; Brain; Chlorambucil; Diaphragm; Esophagus; Gastrointestinal Tract; Growth; Heart; Humans; Kidney; Liver; Lung; Male; Mechlorethamine; Melphalan; Pharmacology; Prostate; Rats; Research; Spleen; Testis; Thiotepa; Thymus Gland; Urinary Bladder | 1964 |
MELPHALAN (PHENYLALANIN NITROGEN MUSTARD) -TREATMENT IN MYELOMATOSIS.
Topics: Albuminuria; Blood Protein Electrophoresis; Humans; Leukocyte Disorders; Leukopenia; Mechlorethamine; Melphalan; Multiple Myeloma; Neoplasms; Thrombocytopenia | 1964 |
[REGIONAL PERFUSION BY EXTRACORPOREAL CIRCULATION. INITIAL RESULTS].
Topics: Chemotherapy, Cancer, Regional Perfusion; Heart, Artificial; Mechlorethamine; Melphalan; Neoplasms; Perfusion; Thiotepa | 1964 |
ABDOMINAL PERFUSION FOR CANCER CHEMOTHERAPY USING HYPOTHERMIA AND HYPERTHERMIA.
Topics: Abdomen; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Cyclophosphamide; Female; Geriatrics; Hodgkin Disease; Humans; Hypothermia; Hypothermia, Induced; Leiomyosarcoma; Mechlorethamine; Melanoma; Melphalan; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Pelvis; Rectal Neoplasms; Retroperitoneal Neoplasms; Uterine Cervical Neoplasms; Vaginal Neoplasms | 1964 |
INTRALYMPHATIC CHEMOTHERAPY WITH CYTOTOXIC DRUGS IN RABBITS.
Topics: Antineoplastic Agents; Cyclophosphamide; Injections; Injections, Intralymphatic; Lymphatic System; Mechlorethamine; Melphalan; Oils; Pathology; Propylene Glycols; Rabbits; Research; Toxicology; Triaziquone | 1964 |
[Studies on the effect of sarcolysine on transplantable tumors of mice].
Topics: Animals; Mechlorethamine; Melphalan; Mice; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1961 |
Adenine-containing DNA-DNA cross-links of antitumor nitrogen mustards.
Topics: Adenine; Animals; Antineoplastic Agents, Alkylating; Cattle; Chromatography, High Pressure Liquid; Cross-Linking Reagents; DNA; DNA Damage; Mechlorethamine; Melphalan; Spectrometry, Mass, Electrospray Ionization | 2004 |
The combination of thalidomide, cyclophosphamide and dexamethasone is potentially useful in highly resistant Hodgkin's lymphoma.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dacarbazine; Deoxycytidine; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Hodgkin Disease; Humans; Male; Mechlorethamine; Melphalan; Organoplatinum Compounds; Paclitaxel; Peripheral Blood Stem Cell Transplantation; Prednisolone; Prednisone; Procarbazine; Remission Induction; Rituximab; Salvage Therapy; Thalidomide; Topotecan; Transplantation, Autologous; Vidarabine; Vinblastine; Vincristine | 2010 |
Increased expression of VDAC1 sensitizes carcinoma cells to apoptosis induced by DNA cross-linking agents.
Topics: Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Cell Line, Tumor; Cisplatin; Colonic Neoplasms; Cross-Linking Reagents; DNA; Female; HeLa Cells; Humans; Mechlorethamine; Melphalan; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Proto-Oncogene Proteins c-bcl-2; Uterine Cervical Neoplasms; Voltage-Dependent Anion Channel 1 | 2012 |
The mechanism of guanine alkylation by nitrogen mustards: a computational study.
Topics: Adenine; Alkylation; Antineoplastic Agents, Alkylating; Guanine; Kinetics; Mechlorethamine; Melphalan; Molecular Structure; Quantum Theory; Thermodynamics | 2012 |
Risk of therapy-related secondary leukemia in Hodgkin lymphoma: the Stanford University experience over three generations of clinical trials.
Topics: Academic Medical Centers; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; California; Chemotherapy, Adjuvant; Clinical Trials as Topic; Dacarbazine; Databases, Factual; Doxorubicin; Drug Administration Schedule; Female; Hodgkin Disease; Humans; Incidence; Leukemia, Myeloid, Acute; Male; Mechlorethamine; Melphalan; Methotrexate; Myelodysplastic Syndromes; Neoplasm Staging; Neoplasms, Second Primary; Prednisone; Procarbazine; Radiotherapy Dosage; Radiotherapy, Adjuvant; Retrospective Studies; Risk; Vinblastine; Vincristine | 2013 |
Mechlorethamine, vincristine, melphalan and prednisone (MOMP) for the treatment of relapsed lymphoma in dogs.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Dog Diseases; Dogs; Female; Lymphoma; Lymphoma, B-Cell; Lymphoma, T-Cell; Male; Mechlorethamine; Melphalan; Prednisone; Recurrence; Survival Analysis; Vincristine | 2015 |
Effect of phenylalanine nitrogen mustard on tissues in culture.
Topics: Immunologic Tests; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Phenylalanine; Research Design; Tissue Culture Techniques | 1957 |
Comparison of the Lonidamine Potentiated Effect of Nitrogen Mustard Alkylating Agents on the Systemic Treatment of DB-1 Human Melanoma Xenografts in Mice.
Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Chlorambucil; Cyclophosphamide; Doxorubicin; Drug Synergism; Humans; Indazoles; Male; Mechlorethamine; Melanoma; Melphalan; Mice; Mice, Nude; Mice, SCID; Xenograft Model Antitumor Assays | 2016 |
Mechlorethamine, vincristine, melphalan and prednisolone rescue chemotherapy protocol for resistant feline lymphoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cat Diseases; Cats; Disease-Free Survival; Female; Lymphoma; Male; Mechlorethamine; Melphalan; Neoplasm Recurrence, Local; Prednisolone; Records; Retrospective Studies; Tennessee; Treatment Outcome; Vincristine | 2018 |