mechlorethamine and guanine

mechlorethamine has been researched along with guanine in 21 studies

Research

Studies (21)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (33.33)	18.7374
1990's	12 (57.14)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (9.52)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Mattes, WB	1
Bingham, JP; Hartley, JA; Souhami, RL	1
Erickson, LC; Futscher, BW; Pieper, RO	1
Grueneberg, DA; Loechler, EL; Ojwang, JO	1
Hartley, JA; Kohn, KW; Mattes, WB	1
Prakash, L; Sherman, F	1
Tomasz, M	1
Kohn, KW; Spears, CL	1
Gray, PJ; Masta, A; Phillips, DR	1
Boussiotis, VA; Kyrtopoulos, SA; Pangalis, GA; Souliotis, VL; Valavanis, C	1
Guziec, FS; Guziec, LJ; Kohn, KW; O'Connor, PM; Orr, A	1
Bohr, VA; Larminat, F; May, A; Petersen, LN; Pirsel, M; Stevnsner, T	1
Laval, J; Lee, CS; Mattes, WB; O'Connor, TR	1
Broch, H; Hamza, A; Vasilescu, D	1
Swenberg, CE; Vaishnav, YN	1
Afonina, IA; Belousov, ES; Gall, AA; Gamper, HB; Kutyavin, IV; Meyer, RB; Reed, MW; Wydro, RM	1
Marino, MT; Skanchy, D; Sperry, ML	1
Haworth, IS; Mitas, M; Romero, RM	1
BROOKES, P; LAWLEY, PD	1
Baik, MH; Polavarapu, A; Stillabower, JA; Stubblefield, SG; Taylor, WM	1
Chatterjee, S; Karmakar, S; Mukherjee, A; Purkait, K	1

Reviews

1 review(s) available for mechlorethamine and guanine

Article	Year
ALKYLATING AGENTS. British medical bulletin, 1964, Volume: 20 Topics: Adenine; Alkylating Agents; Carcinogens; Chemical Phenomena; Chemistry; Cytosine; DNA; Ethers; Ethers, Cyclic; Guanine; Humans; Imines; Lactones; Mechlorethamine; Methane; Mutation; Nucleic Acids; Research; Thymine	1964

Other Studies

20 other study(ies) available for mechlorethamine and guanine

Article	Year
Use of [8-3H]guanine-labeled deoxyribonucleic acid to study alkylating agent reaction kinetics and stability. Analytical biochemistry, 1992, Volume: 206, Issue:1 Topics: Alkylating Agents; Aminoacridines; Cold Temperature; Dimethyl Sulfoxide; DNA; Drug Stability; Guanine; Isotope Labeling; Kinetics; Mechlorethamine; Nitrogen Mustard Compounds; Quinacrine Mustard; Sensitivity and Specificity; Tritium	1992
DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards is preserved in intact cells. Nucleic acids research, 1992, Jun-25, Volume: 20, Issue:12 Topics: Alkylation; Base Sequence; DNA; Guanine; Humans; Mechlorethamine; Molecular Sequence Data; Quinacrine Mustard; Tumor Cells, Cultured; Uracil Mustard	1992
Transcription-terminating lesions induced by bifunctional alkylating agents in vitro. Carcinogenesis, 1989, Volume: 10, Issue:7 Topics: Alkylating Agents; Alkylation; Base Sequence; Chlorambucil; Cyclophosphamide; DNA; DNA Damage; Exons; Genetic Vectors; Guanine; Humans; Mechlorethamine; Melphalan; Molecular Sequence Data; Plasmids; Proto-Oncogenes; Templates, Genetic; Transcription, Genetic	1989
Synthesis of a duplex oligonucleotide containing a nitrogen mustard interstrand DNA-DNA cross-link. Cancer research, 1989, Dec-01, Volume: 49, Issue:23 Topics: Chemical Phenomena; Chemistry; Cross-Linking Reagents; DNA Damage; DNA, Recombinant; Genetic Vectors; Guanine; In Vitro Techniques; Mechlorethamine; Oligodeoxyribonucleotides	1989
DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards. Nucleic acids research, 1986, Apr-11, Volume: 14, Issue:7 Topics: Alkylation; Base Sequence; Densitometry; DNA, Viral; Formates; Guanine; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Quinacrine Mustard; Structure-Activity Relationship; Substrate Specificity; Sulfuric Acid Esters; T-Phages; Uracil Mustard	1986
Mutagenic specificity: reversion of iso-1-cytochrome c mutants of yeast. Journal of molecular biology, 1973, Sep-05, Volume: 79, Issue:1 Topics: Adenine; Alkanesulfonates; Amino Acid Sequence; Base Sequence; Cytochrome c Group; Cytosine; Genetic Code; Guanine; Imidazoles; Lactones; Mechlorethamine; Mesylates; Mutation; Nitrites; Nitrosoguanidines; Radiation Effects; Saccharomyces cerevisiae; Sulfuric Acids; Thymine; Ultraviolet Rays; Uridine	1973
Novel assay of 7-alkylation of guanine residues in DNA. Application to nitrogen mustard, triethylenemelamine and mitomycin C. Biochimica et biophysica acta, 1970, Aug-08, Volume: 213, Issue:2 Topics: Alkylation; Chemical Phenomena; Chemistry; DNA, Bacterial; Guanine; Mechlorethamine; Mitomycins; Spectrum Analysis; Streptococcus pneumoniae; Triethylenemelamine; Tritium; Ultraviolet Rays	1970
Stabilization of nitrogen-mustard alkylations and inter-strand cross-links in DNA by alkali. Biochimica et biophysica acta, 1967, Volume: 145, Issue:3 Topics: Alkalies; Alkylation; Carbon Dioxide; Carbon Isotopes; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry, Physical; DNA, Bacterial; Escherichia coli; Guanine; Hydrogen-Ion Concentration; Mechlorethamine; Models, Chemical; Oxidation-Reduction	1967
Molecular basis of nitrogen mustard effects on transcription processes: role of depurination. Nucleic acids research, 1994, Sep-25, Volume: 22, Issue:19 Topics: Alkylation; Animals; Base Sequence; Cattle; DNA; DNA-Directed RNA Polymerases; Escherichia coli; Guanine; Half-Life; Kinetics; Mechlorethamine; Molecular Sequence Data; Promoter Regions, Genetic; Purines; RNA, Messenger; Transcription, Genetic	1994
Comparative dosimetry of O6-methylguanine in humans and rodents treated with procarbazine. Carcinogenesis, 1994, Volume: 15, Issue:8 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; DNA; Guanine; Hodgkin Disease; Humans; Leukocytes; Male; Mechlorethamine; Methyltransferases; Mice; Mice, Inbred BALB C; O(6)-Methylguanine-DNA Methyltransferase; Prednisone; Procarbazine; Rabbits; Rats; Species Specificity; Vincristine	1994
Synthesis and DNA-sequence selectivity of a series of mono- and difunctional 9-aminoacridine nitrogen mustards. Journal of medicinal chemistry, 1994, Jan-07, Volume: 37, Issue:1 Topics: Acridines; Alkylation; Base Sequence; Binding Sites; Colonic Neoplasms; DNA; Guanine; Humans; Intercalating Agents; Mechlorethamine; Molecular Sequence Data; Molecular Structure; Nitrogen Mustard Compounds; Tumor Cells, Cultured	1994
Repair of ribosomal RNA genes in hamster cells after UV irradiation, or treatment with cisplatin or alkylating agents. Carcinogenesis, 1993, Volume: 14, Issue:8 Topics: Alkylating Agents; Animals; CHO Cells; Cisplatin; Cricetinae; DNA Damage; DNA Repair; DNA, Ribosomal; Genes; Guanine; Mechlorethamine; Methyl Methanesulfonate; Pyrimidine Dimers; RNA Polymerase I; RNA Polymerase II; RNA, Ribosomal; Tetrahydrofolate Dehydrogenase; Transcription, Genetic; Ultraviolet Rays	1993
Excision of DNA adducts of nitrogen mustards by bacterial and mammalian 3-methyladenine-DNA glycosylases. Carcinogenesis, 1996, Volume: 17, Issue:4 Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; Chlorambucil; DNA Adducts; DNA Glycosylases; Escherichia coli; Guanine; Humans; Mechlorethamine; Melphalan; Molecular Sequence Data; N-Glycosyl Hydrolases; Rats	1996
Quantum molecular modeling of the interaction between guanine and alkylating agents--2--nitrogen mustard. Journal of biomolecular structure & dynamics, 1996, Volume: 13, Issue:6 Topics: Alkylating Agents; Alkylation; Aziridines; Guanine; Mechlorethamine; Models, Chemical; Models, Molecular; Quantum Theory	1996
Mechlorethamine-induced enhancement of radiation sensitivity of guanine. International journal of radiation biology, 1996, Volume: 70, Issue:6 Topics: Chromatography, High Pressure Liquid; DNA Adducts; Drug Interactions; Guanine; Hydrogen-Ion Concentration; Mechlorethamine; Radiation Tolerance	1996
Triplex targeting of a native gene in permeabilized intact cells: covalent modification of the gene for the chemokine receptor CCR5. Nucleic acids research, 1998, Mar-01, Volume: 26, Issue:5 Topics: Alkylating Agents; Base Sequence; Berberine Alkaloids; Cell Line; DNA; Gene Targeting; Guanine; Humans; Intercalating Agents; Mechlorethamine; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Receptors, CCR5; Transfection	1998
High-performance liquid chromatographic determination of N-[2-(hydroxyethyl)-N-(2-(7-guaninyl)ethyl)]methylamine, a reaction product between nitrogen mustard and DNA and its application to biological samples. Journal of chromatography. B, Biomedical sciences and applications, 1998, Sep-25, Volume: 716, Issue:1-2 Topics: Animals; Cattle; Chromatography, High Pressure Liquid; DNA; Formates; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Indicators and Reagents; Mass Spectrometry; Mechlorethamine; Methanol; Molecular Weight; Sensitivity and Specificity; Spectrophotometry, Ultraviolet	1998
Anomalous cross-linking by mechlorethamine of DNA duplexes containing C-C mismatch pairs. Biochemistry, 1999, Mar-23, Volume: 38, Issue:12 Topics: Alkylating Agents; Alkylation; Base Pair Mismatch; Bisbenzimidazole; Cross-Linking Reagents; DNA; Guanine; Hydrogen-Ion Concentration; Mechlorethamine; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Piperidines; Sulfuric Acid Esters	1999
The mechanism of guanine alkylation by nitrogen mustards: a computational study. The Journal of organic chemistry, 2012, Jul-20, Volume: 77, Issue:14 Topics: Adenine; Alkylation; Antineoplastic Agents, Alkylating; Guanine; Kinetics; Mechlorethamine; Melphalan; Molecular Structure; Quantum Theory; Thermodynamics	2012
Anticancer activity of a cis-dichloridoplatinum(ii) complex of a chelating nitrogen mustard: insight into unusual guanine binding mode and low deactivation by glutathione. Dalton transactions (Cambridge, England : 2003), 2016, Feb-28, Volume: 45, Issue:8 Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Cell Cycle; Cell Survival; Chelating Agents; Chick Embryo; Cytoplasm; Glutathione; Guanine; Humans; Ligands; MCF-7 Cells; Mechlorethamine; Membrane Potential, Mitochondrial; Methylamines; Neovascularization, Physiologic; Organoplatinum Compounds; Stereoisomerism	2016