mechlorethamine and cysteine

mechlorethamine has been researched along with cysteine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199023 (82.14)18.7374
1990's0 (0.00)18.2507
2000's3 (10.71)29.6817
2010's1 (3.57)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Donelli, MG; Garattini, S; Rosso, R1
Elson, LA1
Farah, A; Gussin, RZ; Miksche, U1
Baba, T; Nishikawa, K1
Fenselau, C; Szilágyi, Z1
Hulst, AG; Jansen, R; Noort, D1
SCHLANG, HA1
FRANKE, R; KELLER, N; THIELE, FH1
IMAMURA, H; ISHIDATE, M; MATUI, E; SAKURAI, Y; SATOH, H; YOSHIDA, T1
STORAASLI, JP; WEISBERGER, AS1
TORIGOE, M1
BEVACQUA, V; GARAVAGLIA, GP1
DEYSSON, G; TRUHAUT, R1
MATSUI, E; SAKURAI, Y1
GOLDENTHAL, EI; NADKARNI, MV; SMITH, PK1
SCHUNK, J1
CONTRACTOR, SF1
HIETBRINK, BE; RAYMUND, AB1
HO, S1
ACTON, EM; BAKER, BR; GOODMAN, L; IWAMOTO, RH; ROSS, LO; SKINNER, WA1
CONNORS, TA; JENEY, A; JONES, M1
HEINLE, RW; WEISBERGER, AS2
BRANDT, EL; GRIFFIN, AC1
HEINLE, RW; LEVINE, B; WEISBERGER, AS1
Bayley, H; Wu, HC1
An, Y; Heck, DE; Jan, YH; Laskin, DL; Laskin, JD1

Reviews

1 review(s) available for mechlorethamine and cysteine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

27 other study(ies) available for mechlorethamine and cysteine

ArticleYear
On the neurotoxic effects induced by alkylating agents.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:11

    Topics: Alanine; Animals; Anti-Bacterial Agents; Antimetabolites; Azaserine; Behavior, Animal; Central Nervous System; Chlorambucil; Cyclophosphamide; Cysteine; Drug Antagonism; Glycine; Male; Mannitol; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Phenobarbital; Phenytoin; Rats; Seizures; Spasm; Thiourea; Triethylenemelamine; Tryptophan

1966
Growth inhibitory and haematological effects of alkylating agents and attempts at their modification to give greater selectivity of anti-tumour action.
    Acta geneticae medicae et gemellologiae, 1968, Volume: 17, Issue:1

    Topics: Alkylating Agents; Animals; Body Weight; Carcinoma 256, Walker; Chemical Phenomena; Chemistry; Chlorambucil; Cysteine; Hematopoiesis; Mechlorethamine; Mice; Mitosis; Neoplasms, Experimental; Rats

1968
Alkylating agents and the effects of antidiuretic hormone in the toad bladder.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 156, Issue:3

    Topics: Adenine Nucleotides; Amphotericin B; Animals; Anura; Biological Transport; Cysteine; Diuresis; Electrophysiology; Mechlorethamine; Oxygen Consumption; Thiosulfates; Urinary Bladder; Vasopressins; Water

1967
Effective combination of anticancer drug with its antidote for chemotherapy of hepatic metastasis.
    Gan, 1980, Volume: 71, Issue:1

    Topics: Animals; Antidotes; Cysteine; Drug Therapy, Combination; Female; Hepatic Artery; Injections, Intra-Arterial; Injections, Intravenous; Liver Neoplasms; Mechlorethamine; Rats; Sarcoma, Experimental

1980
Molecular dynamics simulation of metallothionein-drug complexes.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:2

    Topics: Binding Sites; Chemical Phenomena; Chemistry, Physical; Chlorambucil; Computer Simulation; Crystallography, X-Ray; Cysteine; Mechlorethamine; Melphalan; Metallothionein; Models, Structural; Nitrogen Mustard Compounds; Protein Binding; Zinc

2000
Covalent binding of nitrogen mustards to the cysteine-34 residue in human serum albumin.
    Archives of toxicology, 2002, Volume: 76, Issue:2

    Topics: Binding Sites; Chlorambucil; Cyclophosphamide; Cysteine; Drug Monitoring; Humans; In Vitro Techniques; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Protein Binding; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2002
Shwartzman phenomenon. III. Modifications of nitrogen-mustard suppression.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1952, Volume: 81, Issue:1

    Topics: Cysteine; Hypersensitivity; Immune System Diseases; Leukocytes; Mechlorethamine; Mustard Plant; Nitrogen; Nitrogen Mustard Compounds; Shwartzman Phenomenon

1952
[Studies on the effects of nitrogen mustard and their variation under the influence of cystein; studies on blood picture, blood proteins, plasmal reaction of the adrenal cortex, and 17-ketosteroid excretion].
    Zeitschrift fur die gesamte experimentelle Medizin, 1953, Volume: 120, Issue:4

    Topics: 17-Ketosteroids; Adrenal Cortex; Adrenal Glands; Blood; Blood Proteins; Cysteine; Humans; Lipid Metabolism; Mechlorethamine; Nitrogen Mustard Compounds; Phospholipids; Steroids

1953
[Studies on the toxicity of nitromin; interference of cystein upon nitromin toxicity].
    Gan, 1953, Volume: 44, Issue:2-3

    Topics: Cysteine; Mechlorethamine; Nitrogen Mustard Compounds

1953
Optical isomers of cysteine in the prevention of leukopenia induced by nitrogen mustard.
    The Journal of laboratory and clinical medicine, 1954, Volume: 43, Issue:2

    Topics: Cysteine; Leukocyte Count; Leukocyte Disorders; Leukopenia; Mechlorethamine; Nitrogen Mustard Compounds

1954
Reaction of cysteine with nitrogen mustards and their N-oxides.
    Pharmaceutical bulletin, 1953, Volume: 1, Issue:4

    Topics: Cysteine; Mechlorethamine; Nitrogen Mustard Compounds; Oxides

1953
[Inhibitory effect of cysteine on leukopenia produced by nitrogen mustard].
    Haematologica, 1954, Volume: 38, Issue:7

    Topics: Cysteine; Leukocyte Count; Leukopenia; Mechlorethamine; Nitrogen Mustard Compounds

1954
[New research on the protective effect exercised by diverse sulfhydryl compounds in comparison with toxicity of nitrogen mustards and triethylene melamine].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Nov-18, Volume: 150, Issue:6

    Topics: Cysteine; Exercise; Glutamine; Mechlorethamine; Nitrogen Mustard Compounds; Research; Sulfhydryl Compounds; Triethylenemelamine

1956
Life-prolongation of Yoshida sarcoma rat under a concomitant treatment of nitromin and cysteine.
    Gan, 1956, Volume: 47, Issue:3-4

    Topics: Animals; Cysteine; Humans; Life Support Care; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds; Rats; Sarcoma, Yoshida

1956
A study of comparative protection against lethality of triethylenemelamine, nitrogen mustard, and x-irradiation in mice.
    Radiation research, 1959, Volume: 10, Issue:5

    Topics: Animals; Cysteine; Mechlorethamine; Mercaptoethylamines; Mice; Nitrites; Nitrogen Mustard Compounds; Radiation Protection; Triethylenemelamine

1959
[On the protective effect of beta-aminoethyliso-thiuronium (AET) and alpha-homocysteine thiolactone (HCT) against nitrogen-lost in the mouse].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1960, Volume: 238

    Topics: Animals; Cysteine; Homocysteine; Mechlorethamine; Mice; Nitrogen; Nitrogen Mustard Compounds; Sulfhydryl Compounds

1960
PROTECTION AGAINST NITROGEN MUSTARD BY CYSTEINE AND RELATED SUBSTANCES, INVESTIGATED USING (3H)METHYL-DI-(2-CHLOROETHYL) AMINE.
    Biochemical pharmacology, 1963, Volume: 12

    Topics: Amines; Cystamine; Cysteamine; Cysteine; Mechlorethamine; Mice; Penicillamine; Pharmacology; Radiation-Protective Agents; Research; Tritium

1963
THE INFLUENCE OF SOME SULFUR-CONTAINING COMPOUNDS ON THE TOXICITY OF NITROGEN MUSTARDS.
    Toxicology and applied pharmacology, 1963, Volume: 5

    Topics: Adenosine Triphosphatases; Carbamates; Cholinesterases; Cysteine; Esters; Glutathione; Intestine, Small; Intestines; Mechlorethamine; Mercaptoethylamines; Metabolism; Nitrogen Mustard Compounds; Pharmacology; Rats; Research; Spleen; Sulfhydryl Compounds; Sulfur; Sulfur Compounds; Toxicology

1963
[STUDIES ON ANTITUMOR DRUGS. V. A STUDY ON CERTAIN COMBINATIONS OF ANTITUMOR AGENTS].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1963, Volume: 10

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cysteine; Diethylstilbestrol; Mechlorethamine; Mercaptopurine; Mice; Neoplasms; Pharmacology; Research; Sarcoma; Sarcoma 180; Sarcoma, Experimental

1963
POTENTIAL ANTICANCER AGENTS. LXXIX. AROMATIC NITROGEN MUSTARDS DERIVED FROM CYSTEINE.
    Journal of medicinal chemistry, 1963, Volume: 6

    Topics: Antineoplastic Agents; Carcinoma; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Cysteine; Mechlorethamine; Nitrogen Mustard Compounds; Pharmacology; Rats; Research

1963
REDUCTION OF THE TOXICITY OF 'RADIOMIMETIC' ALKYLATING AGENTS IN RATS BY THIOL PRETREATMENT. 3. THE MECHANISM OF THE PROTECTIVE ACTION OF THIOSULPHATE.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Alkylating Agents; Cysteine; Mechlorethamine; Nitrogen Mustard Compounds; Pharmacology; Rats; Research; Sulfhydryl Compounds; Thiosulfates; Toxicology

1964
The protective effect of cysteine on leucopenia induced by nitrogen mustard.
    The Journal of laboratory and clinical medicine, 1950, Volume: 36, Issue:6

    Topics: Cysteine; Leukocyte Disorders; Leukocytes; Leukopenia; Mechlorethamine; Nitrogen Mustard Compounds

1950
Protective effect of cysteine against leucopenia induced by nitrogen mustard.
    The Journal of laboratory and clinical medicine, 1950, Volume: 36, Issue:6

    Topics: Cysteine; Leukocyte Disorders; Leukocytes; Leukopenia; Mechlorethamine; Nitrogen Mustard Compounds

1950
Reduction of toxicity of nitrogen mustards by cysteine.
    Cancer, 1951, Volume: 4, Issue:5

    Topics: Cysteine; Mechlorethamine; Nitrogen Mustard Compounds

1951
The effect of L-cysteine on nitrogen mustard therapy.
    The American journal of the medical sciences, 1952, Volume: 224, Issue:2

    Topics: Cysteine; Mechlorethamine; Nitrogen Mustard Compounds

1952
Single-molecule detection of nitrogen mustards by covalent reaction within a protein nanopore.
    Journal of the American Chemical Society, 2008, May-28, Volume: 130, Issue:21

    Topics: Cysteine; Glutathione; Hemolysin Proteins; Lipid Bilayers; Mechlorethamine; Nanostructures; Nitrogen Mustard Compounds; Phosphatidylcholines; Protein Engineering; Protein Structure, Secondary; Sulfhydryl Compounds

2008
Nitrogen Mustard Alkylates and Cross-Links p53 in Human Keratinocytes.
    Chemical research in toxicology, 2022, 04-18, Volume: 35, Issue:4

    Topics: Chromatography, Liquid; Cysteine; Humans; Keratinocytes; Mechlorethamine; Tandem Mass Spectrometry; Tumor Suppressor Protein p53

2022