mechlorethamine and choline

mechlorethamine has been researched along with choline in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199023 (88.46)18.7374
1990's3 (11.54)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inaba, M; Sakurai, Y1
Goldenberg, GJ2
Bohunická, E; Kolarov, J; Krempaský, V; Kuzela, S; Ujházy, V1
Brendel, M; Haase, E; Li, ZY1
Ritter, C; Rutman, RJ1
Doppler, W; Grunicke, HH; Hofmann, J; Maly, K1
Cuello, AC; Maysinger, D; Tagari, PC1
Robins, G; Zsigmond, EK1
Goldenberg, GJ; Sinha, BK2
Bergsagel, DE; McCulloch, EA; Ogawa, M1
Goldenberg, GJ; Lepp, JA; Lyons, RM; Vanstone, CL1
Bihler, I; Goldenberg, GJ; Vanstone, CL1
Fisher, JM; Naujokaitis, SA; Rabinovitz, M3
Naujokaitis, SA1
Brendel, M; Li, Z1
Cunliffe, B; Robson, GD; Trinci, APJ; Wiebe, MG1
COLTER, JS; QUASTEL, JH1
MILLER, Z1
KLOPP, CT; TRAMS, EG1
HOWE, GW; MARVIN, N; SPURR, CL1
DOMOKOS, J; KELEMEN, E1
BARRON, ES; BARTLETT, GR; MILLER, ZB1

Other Studies

26 other study(ies) available for mechlorethamine and choline

ArticleYear
Role of DNA repair in natural resistance of rat ascites hepatomas to nitrogen mustard.
    Gan, 1977, Volume: 68, Issue:1

    Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Choline; DNA Repair; DNA, Neoplasm; Drug Resistance; Liver Neoplasms; Mechlorethamine; Neoplasms, Experimental; Rats

1977
Drug-induced stimulation of transport of hydrolyzed nitrogen mustard and choline by normal and leukemic human cells in vitro.
    Cancer research, 1976, Volume: 36, Issue:3

    Topics: Biological Transport; Choline; Cocaine; Dose-Response Relationship, Drug; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocytes; Mechlorethamine; Morphine

1976
Different inhibitory effect of nitrogen mustard (HN2) and TS-160 (HN3) on choline transport in L 5178Y lymphoblasts.
    Neoplasma, 1975, Volume: 22, Issue:6

    Topics: Alkylating Agents; Amines; Animals; Binding, Competitive; Biological Transport; Choline; Leukemia, Experimental; Mechlorethamine; Nitrogen Mustard Compounds

1975
Hyper-resistance to nitrogen mustard in Saccharomyces cerevisiae is caused by defective choline transport.
    Current genetics, 1991, Volume: 19, Issue:6

    Topics: Alleles; Biological Transport; Choline; Cloning, Molecular; DNA Damage; Drug Resistance, Microbial; Genes, Fungal; Mechlorethamine; Phenotype; Saccharomyces cerevisiae

1991
Choline uptake is increased by Ca++ and liposomes+ Ca++ in ascites tumor cells.
    Cancer biochemistry biophysics, 1989, Volume: 10, Issue:4

    Topics: Animals; Biological Transport; Calcium; Carcinoma, Ehrlich Tumor; Carrier Proteins; Choline; Liposomes; Mechlorethamine; Mice; Mice, Inbred ICR; Neoplasm Proteins; Phospholipids; Stimulation, Chemical

1989
Protection of Ehrlich ascites tumor cells against the antiproliferative effect of mechlorethamine (nitrogen mustard) by 5-N,N-dimethylamiloride.
    Cancer research, 1988, May-01, Volume: 48, Issue:9

    Topics: Amiloride; Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Cell Division; Choline; DNA, Neoplasm; Mechlorethamine; Tumor Cells, Cultured

1988
Hemicholinium mustard derivatives: preliminary assessment of cholinergic neurotoxicity.
    Neurochemical research, 1986, Volume: 11, Issue:7

    Topics: Animals; Aziridines; Brain; Cerebral Cortex; Choline; Cholinergic Fibers; Corpus Striatum; Hemicholinium 3; Hippocampus; Injections, Intraventricular; Male; Mechlorethamine; Rats

1986
The effect of a series of anti-cancer drugs on plasma cholinesterase activity.
    Canadian Anaesthetists' Society journal, 1972, Volume: 19, Issue:1

    Topics: Antineoplastic Agents; Benzoates; Choline; Cholinesterase Inhibitors; Cholinesterases; Cyclophosphamide; Dactinomycin; Floxuridine; Fluorouracil; Humans; Hydrolysis; In Vitro Techniques; Mechlorethamine; Procaine; Thiotepa; Triethylenemelamine; Vinblastine; Vincristine

1972
Drug-induced stimulation of nitrogen mustard and choline transport and other systems in L5178Y lymphoblasts in vitro.
    Cancer research, 1974, Volume: 34, Issue:10

    Topics: Amino Acids; Aminoisobutyric Acids; Aminolevulinic Acid; Animals; Atropine; Biological Transport; Cell Line; Cells, Cultured; Choline; Cocaine; Cyclopentanes; Diazepam; Glucose; Leucine; Leukemia, Experimental; Leukemia, Lymphoid; Lymphocytes; Mechlorethamine; Mice; Morphine; Phenobarbital; Stimulation, Chemical

1974
Protection of L5178Y lymphoblasts by choline and ethanolamine against cytocidal effect of nitrogen mustard in vitro.
    Cancer research, 1973, Volume: 33, Issue:6

    Topics: Animals; Binding, Competitive; Choline; Ethanolamines; Female; Hydrolysis; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Lethal Dose 50; Leukemia, Experimental; Leukocyte Count; Lymphocytes; Male; Mechlorethamine; Mice; Mice, Inbred Strains; Rats; Time Factors

1973
Studies of nitrogen mustard transport by mouse myeloma and hemopoietic precursor cells.
    Cancer research, 1973, Volume: 33, Issue:12

    Topics: Animals; Biological Transport, Active; Cell Division; Cell Survival; Cells, Cultured; Choline; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cells; Mechlorethamine; Mice; Mice, Inbred BALB C; Plasmacytoma; Temperature

1973
Nitrogen mustard sensitivity and choline transport in Walker 256 carcinosarcoma cells in vitro.
    Cancer research, 1973, Volume: 33, Issue:11

    Topics: Animals; Binding, Competitive; Biological Transport, Active; Carbon Radioisotopes; Carcinoma 256, Walker; Carrier Proteins; Cell Division; Cells, Cultured; Choline; Dose-Response Relationship, Drug; Kinetics; Mechlorethamine; Rats

1973
Sensitivity to nitrogen mustard as a function of transport activity and proliferative rate in L5178Y lymphoblasts.
    Cancer research, 1971, Volume: 31, Issue:11

    Topics: Animals; Biological Transport; Carbon Isotopes; Cell Division; Cell Line; Cells, Cultured; Choline; Hydrolysis; In Vitro Techniques; Kinetics; Lymphoma; Mechlorethamine; Mice

1971
Transport of nitrogen mustard on the transport-carrier for choline in L5178Y lymphoblasts.
    Science (New York, N.Y.), 1971, Jun-11, Volume: 172, Issue:3988

    Topics: Biological Transport; Carbon Isotopes; Choline; Culture Techniques; Lymphocyte Activation; Lymphocytes; Mechlorethamine

1971
Protection of murine L1210 leukemia and bone marrow progenitor cells against mechlorethamine and inhibition of choline uptake as a structure-activity relationship of 2-dimethylaminoethanol and its analogues.
    Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Cells; Choline; Deanol; Ethanolamines; Female; Leukemia L1210; Male; Mechlorethamine; Mice; Mice, Inbred DBA; Stem Cells; Structure-Activity Relationship

1984
Tetraalkylammonium ions: protection of murine L1210 leukemia and bone marrow progenitor cells in vitro against mechlorethamine cytotoxicity and inhibition of the choline transport system.
    Chemico-biological interactions, 1982, Volume: 40, Issue:2

    Topics: Animals; Biological Transport, Active; Cell Survival; Choline; Clone Cells; Colony-Forming Units Assay; Hematopoietic Stem Cells; Kinetics; Leukemia L1210; Male; Mechlorethamine; Mice; Quaternary Ammonium Compounds

1982
Thiamine protection of murine L1210 leukemia cells against mechlorethamine cytotoxicity and its relation to the choline uptake system.
    Research communications in chemical pathology and pharmacology, 1981, Volume: 32, Issue:2

    Topics: Animals; Biological Transport; Choline; Leukemia L1210; Male; Mechlorethamine; Melphalan; Mice; Thiamine

1981
Ethanol mustard cytotoxicity in vitro toward murine leukemia and bone marrow progenitor cells.
    Research communications in chemical pathology and pharmacology, 1981, Volume: 33, Issue:2

    Topics: Animals; Bone Marrow Cells; Cell Survival; Cells, Cultured; Choline; Colony-Forming Units Assay; Hematopoietic Stem Cells; Kinetics; Leukemia L1210; Male; Mechlorethamine; Mice; Nitrogen Mustard Compounds

1981
Sensitivity to nitrogen mustard in Saccharomyces cerevisiae is independently determined by regulated choline permease and DNA repair.
    Mutation research, 1994, Volume: 315, Issue:2

    Topics: Biological Transport; Carrier Proteins; Choline; DNA Repair; DNA, Fungal; Fungal Proteins; Gene Expression Regulation, Fungal; Inositol; Mechlorethamine; Membrane Transport Proteins; Mutation; Promoter Regions, Genetic; Saccharomyces cerevisiae

1994
Choline- and acetylcholine-induced changes in the morphology of Fusarium graminearum: evidence for the involvement of the choline transport system and acetylcholinesterase.
    Microbiology (Reading, England), 1995, Volume: 141 ( Pt 6)

    Topics: Acetylcholine; Acetylcholinesterase; Acetylglucosamine; Betaine; Biological Transport; Cell Wall; Chitin Synthase; Choline; Cholinesterase Inhibitors; Drug Resistance, Microbial; Ethanolamine; Ethanolamines; Fungal Proteins; Fusarium; Hemicholinium 3; Mechlorethamine; Membrane Proteins; Mutagenesis; Quaternary Ammonium Compounds

1995
Studies of the effects of methyl-bis-beta chloroethylamine and anticholine oxidases on choline metabolism in vitro.
    Archives of biochemistry and biophysics, 1952, Volume: 41, Issue:2

    Topics: Choline; Cholinesterases; In Vitro Techniques; Mechlorethamine; Nitrogen Mustard Compounds; Oxidoreductases

1952
Influence of the ethylenimine structure on the oxidation of choline, formaldehyde and sarcosine.
    Archives of biochemistry and biophysics, 1953, Volume: 47, Issue:1

    Topics: Aziridines; Choline; Formaldehyde; Glycine; Liver; Mechlorethamine; Nitrogen Mustard Compounds; Oxidation-Reduction; Oxidoreductases; Sarcosine; Triethylenemelamine

1953
Distribution of radiocarbon in liver chlorine, creatine, and methionine after the injection of methyl-C14-bis (beta-chloroethyl) amine.
    Cancer research, 1955, Volume: 15, Issue:9

    Topics: Amines; Carbon; Chlorine; Choline; Creatine; Liver; Mechlorethamine; Methionine; Nitrogen Mustard Compounds

1955
Evaluation of choline and related substances as antitoxic agents to nitrogen mustard in vivo.
    Texas reports on biology and medicine, 1952, Volume: 10, Issue:1

    Topics: Choline; Mechlorethamine; Nitrogen Mustard Compounds

1952
[Clinical and animal experiments on the prevention of vomiting and of bone marrow damage due to nitrogen mustard by the use of pyridoxine and choline, respectively].
    Orvosi hetilap, 1950, Jun-04, Volume: 91, Issue:23

    Topics: Animal Experimentation; Animals; Biomedical Research; Bone Marrow; Choline; Humans; Mechlorethamine; Nitrogen Mustard Compounds; Pyridoxine; Vitamin B 6; Vomiting

1950
The effect of nitrogen mustards on enzymes and tissue metabolism; the effect on enzymes.
    The Journal of experimental medicine, 1948, Jun-01, Volume: 87, Issue:6

    Topics: Acetylcholine; Alcohol Oxidoreductases; Choline; Mechlorethamine; Tissues

1948