mechlorethamine has been researched along with chlorambucil in 223 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 180 (80.72) | 18.7374 |
| 1990's | 29 (13.00) | 18.2507 |
| 2000's | 10 (4.48) | 29.6817 |
| 2010's | 4 (1.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hansch, C; Khwaja, TA; Selassie, CD | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Coleman, M; Pasmantier, MW; Silver, RT | 1 |
| Bakemeier, RF; Bennett, JM; Carbone, PP; Ezdinli, E; Lenhard, RE | 1 |
| Ross, GT | 1 |
| Huguley, CM | 1 |
| Cameron, JS | 2 |
| Brendel, M; Fleer, R | 1 |
| Bruntsch, U; Gallmeier, WM | 1 |
| Morley, AA; Seshadri, RS; Trainor, KJ | 1 |
| Chu, JY; DeMello, D; McElfresh, AE; O'Connor, DM; Razek, AA | 1 |
| Bhuyan, BK; Day, KJ; Fraser, TJ; Loughman, BE | 1 |
| Pollak, VE | 1 |
| Aungst, CW; Ezdinli, E; Kaufman, JH; Stutzman, L | 1 |
| Hoagland, HC; Perry, MC | 1 |
| Goldenberg, GJ | 1 |
| Falkson, G; Falkson, HC | 1 |
| Gascoigne, EW; Harrap, KR | 1 |
| Avilés, A; Ayala, JR; Cortés, HD; Díaz-Maqueo, JC; García, EL | 1 |
| Bensman, A; Boccon-Gibod, L; Gruner, M; Leverger, G; Parlier, G | 1 |
| Bennett, MH; Douglas, AJ; Hudson, BV; Hudson, GV; MacLennan, KA; Swerdlow, AJ | 1 |
| Alaoui-Jamali, MA; Batist, G; Centurioni, GM; Lehnert, S; Panasci, L; Schecter, R | 1 |
| Bauer, GB; Bennett, RA; Povirk, LF; Wang, P | 1 |
| Ashley, S; Brada, M; Crow, J; Horwich, A; O'Brien, P | 1 |
| Bennett, MH; Hancock, BW; Haybittle, JL; Jelliffe, AM; MacLennan, KA; Vaughan Hudson, B; Vaughan Hudson, G | 1 |
| Erickson, LC; Pieper, RO | 1 |
| Coiffier, B; Gisselbrecht, C; Lepage, E; Sebban, C | 1 |
| Trompeter, RS | 2 |
| Erickson, LC; Futscher, BW; Pieper, RO | 1 |
| Canellos, GP; Druker, BJ; Rosenthal, DS | 1 |
| Calabrese, LH; Capraro, JA; Holden, D; Zelenski, JD | 1 |
| Bernengo, MG; Jemma, C; Lisa, F; Meregalli, M | 1 |
| Doppler, W; Grunicke, H; Hofmann, J; Lindner, H; Maly, K; Oberhuber, H; Ringsdorf, H; Roberts, JJ | 1 |
| Ekert, H; Mauger, D; Smith, PJ; Toogood, I; Waters, KD | 1 |
| Doppler, W; Grunicke, H; Helliger, W; Hermann, BJ; Höck, W; Hofmann, J; Maly, K; Puschendorf, B | 1 |
| Armitage, J; Dowling, M; Howe, D; Hutchins, M; Moravec, D; Okerbloom, J; Pevnick, W; Sorensen, S; Vose, J; Weisenburger, D | 1 |
| Hancock, BW | 1 |
| Buller, AL; Clapper, ML; Tew, KD | 1 |
| Berneman, ZN; Bieger, R; Bridts, C; Buyssens, N; Hautekeete, ML; Peetermans, ME; Stevens, WJ | 1 |
| Bourke, JP; Boyle, E; Conroy, R; Duggan, J; Fennelly, JJ; McCabe, M; Warde, P | 1 |
| Cintrón-López, J; Fradera, J; Martínez-Poventud, G; Vélez-García, E | 1 |
| Ersbøll, J; Keiding, N; Larsen, MS; Larsen, SO; Nissen, NI; Pedersen-Bjergaard, J; Philip, P; Schultz, H; Sørensen, HM | 1 |
| Boulton-Jones, M; Cameron, JS; Ogg, C; Robinson, R | 1 |
| Desser, RK; Ultmann, JE | 1 |
| Stacher, A | 1 |
| al-Mondhiry, H; Connolly, CE; Lacher, MJ; Sahakian, GJ | 1 |
| McLaren, JH; Papac, RJ | 1 |
| Wojnarowski, M; Wyszyńska, T | 1 |
| Leĭkina, FI; Smolianskaia, AZ | 1 |
| Huart, M | 1 |
| Bradley, SG; Munson, AE; Rose, WC | 1 |
| Du Priest, RW; Fletcher, WS | 1 |
| Carter, SK; Comis, RL | 1 |
| Brun, M; Camargo, R; Girard, P; Pellet, H | 1 |
| Donelli, MG; Garattini, S; Rosso, R | 1 |
| Han, T; Reilly, CJ; Slack, NH; Stutzman, L; Webster, J | 1 |
| Habib, R; Levy, M | 1 |
| Galvanek, EG; Lokich, JJ; Moloney, WC | 1 |
| Tolen, SJ; Valeriote, FA | 1 |
| Greenwald, ES | 1 |
| Carter, SK; Livingston, RB | 1 |
| Fairley, GH | 1 |
| Glidewell, OJ; Holland, JF; Nissen, NI; Stutzman, L | 1 |
| Sladek, NE | 1 |
| Ackerman, GA; Folk, RM; Goodman, MT | 1 |
| DeVita, VT | 1 |
| Pengelly, CD | 1 |
| Ackerman, GA; Goodman, MT | 1 |
| Jacobs, EM; Luce, JK; Peters, FC; Wood, DA; Zippin, C | 1 |
| Bariéty, J; Fritel, D; Lagrue, G; Milliez, P; Samarcq, P | 1 |
| Baum, J; Vaughan, J | 1 |
| Nixon, DD; Ultmann, JE | 1 |
| Currey, HL | 1 |
| Carbone, PP; DeVita, VT | 1 |
| Carlisle, HN; Saslaw, S | 1 |
| Berceanu, S; Dăncescu, I; Geib, R; Gociu, M; Segal, E; Sighetea, E; Tănăsescu, C | 1 |
| Kunii, A; Tanaka, M; Yamada, K | 1 |
| Gueguen, MH | 1 |
| Lenhard, RE; Owens, AH | 1 |
| Wasastjerna, C | 1 |
| Bihler, I; Goldenberg, GJ; Iise, D; Israels, LG; Vanstone, CL | 1 |
| Lelieveld, P; van Putten, LM | 1 |
| Bishop, RC | 1 |
| Elson, LA | 1 |
| Budnitz, J; Haidak, G; Stern, OS; Tulgan, H | 1 |
| Barbier, P; Jacobs, E; Manaster, J; Robert, J | 1 |
| Orsini, A; Pierron, H; Unal, D | 1 |
| Rowecka-Trzebicka, K; Wojnarowski, M; Wyszyńska, T | 1 |
| Bodalski, J; Margolis, A; Michalak, A; Nowak, S | 1 |
| Bariéty, J; Jacquillat, C; Lagrue, G; Milliez, P | 1 |
| Gellhorn, A | 1 |
| Jenkin, RD | 1 |
| Dameshek, W; Lewis, FB; Schwartz, RS | 1 |
| Williamson, CE; Witten, B | 1 |
| Gupta, VS; Huennekens, FM; Ozols, JG | 1 |
| Brauer, MJ; McEvoy, BF; Mitus, WJ | 1 |
| Soukup, S; Takacs, E; Warkany, J | 1 |
| Gitter, S; Lavie, D; Shohat, B | 1 |
| Malpas, JS | 1 |
| Glick, JH; Taylor, SG; Zehngebot, LM | 1 |
| Goldman, JM | 1 |
| Canals, MJ; Cervera, A; Gómez Campderá, FJ; Gómez Campderá, J; López Gómez, JM; Luque, A; Morales, JL | 1 |
| Corder, MP; Ellwein, LB | 1 |
| Pasqualini, T | 1 |
| Hemminki, K; Kallama, S | 1 |
| Parsons, PG | 1 |
| Hetzel, FW; Kaufman, N | 1 |
| Estes, RG; McLeod, R | 1 |
| Benckhuysen, C; van der Steen, J; van Wichen, BH | 1 |
| Rose, GM | 1 |
| Bicher, HI; Brown, M; Hetzel, FW; Kaufman, N | 1 |
| Lu, LC; Weinerman, BH | 1 |
| Strickland, P | 1 |
| Gabryś, K; Kotlarek-Haus, S; Potoczek, S | 1 |
| Povirk, LF; Shuker, DE | 1 |
| Arnott, S; Crowther, D; Deakin, DP; Gupta, RK; James, RD; Oza, A; Radford, JA; Rohatiner, AZ; Ryder, WD; Wilkinson, PM | 1 |
| Watkins, SM | 1 |
| Haworth, IS; Lee, CS; Remias, MG | 1 |
| Clark, ST; Crowther, D; Radford, JA; Shalet, SM; Swindell, R | 1 |
| Atkinson, CH; Colls, BM; Fitzharris, BM; Robinson, BA | 1 |
| Assar, H; Batist, G; Cournoyer, D; Greenbaum, M; Létourneau, S; Schecter, RL | 1 |
| Alaoui-Jamali, MA; Batist, G; Fahl, WE; Schecter, RL; Woo, A | 1 |
| Azen, C; Fichman, M; Klinenberg, JR; Metzger, AL; Nessim, S; Neumann, K; Wallace, DJ | 1 |
| Doi, T; Nagai, H; Suzuki, T; Tsukuda, R | 1 |
| Laval, J; Lee, CS; Mattes, WB; O'Connor, TR | 1 |
| Luedtke, NW; Millard, JT; Spencer, RJ | 1 |
| Cournoyer, D; Greenbaum, M; Letourneau, S | 1 |
| Barber, JA; Cunningham, D; Horwich, A; Milan, S; Omar, RZ; Swerdlow, AJ | 1 |
| Cairns, MJ; Denny, WA; Murray, V; Temple, MD | 1 |
| Hopkins, PB; Millard, JT; Spencer, RJ | 1 |
| Hesseling, PB; Van Jaarsveld, D; Van Riet, FA; Wessels, G | 1 |
| Chow, TY; Cournoyer, D; Semionov, A | 1 |
| Devereux, S; Goldstone, AH; Gregory, W; Hancock, B; Harrison, CN; Hoskin, P; Hudson, GV; Linch, DC; MacMillan, AK; Milligan, D; Newland, AC; Winfield, D | 1 |
| Fenselau, C; Szilágyi, Z | 1 |
| Ferguson, LR; Marcinkowski, K; Turner, PM; Wu, XC | 1 |
| Aloyz, R; Belenkov, A; Christodoulopoulos, G; Malapetsa, A; Paiement, JP; Panasci, L | 1 |
| Nivard, MJ; Vogel, EW; Wijen, JP | 1 |
| Hulst, AG; Jansen, R; Noort, D | 1 |
| Carde, P; Cavalli, F; Diehl, V; Franklin, J | 1 |
| Bhatia, S; Curtis, RE; Fay, JW; Freytes, CO; Goldstein, SC; Herzig, RH; Horowitz, MM; Keating, A; Li, CY; Metayer, C; Miller, CB; Nevill, TJ; Pecora, AL; Rizzo, JD; Sobocinski, KA; Travis, LB; Vose, J; Weisdorf, DJ; Williams, SF | 1 |
| GALTON, DA; ISRAELS, LG; NABARRO, JD; TILL, M | 1 |
| BOURONCLE, BA; DOAN, CA; FRAJOLA, WJ; WISEMAN, BK | 1 |
| HANSEN, PB | 1 |
| ROTTINO, A | 1 |
| LAMY, P; REMIGY, E; STEHLIN, H | 1 |
| OLNEY, MB; WOLFSON, S | 1 |
| BRABEC, V; CHUDOMEL, V; LIBANSKY, J; SOCHMAN, J | 2 |
| BURCHENAL, JH; KARNOFSKY, DA; KRAKOFF, IH | 1 |
| DE VRIES, SI | 1 |
| FORSGREN, AL; KOLER, RD | 1 |
| ELSON, LA; GALTON, DA; TILL, M | 1 |
| GALTON, DA; ISRAELS, LG; TILL, M; WILTSHAW, E | 1 |
| BOURONCLE, BA; DOAN, CA; WISEMAN, BK | 1 |
| GELLHORN, A; HYMAN, GA; ULTMANN, JE | 1 |
| OLSON, KB | 1 |
| GOLOMB, FM; GUMPORT, SL; WRIGHT, JC | 1 |
| ARCADIO, F; COLOMB, D; FAYOLLE, J; THIERS, H | 1 |
| GOLDENTHAL, EI; HURWITZ, L; YOUNG, RS | 1 |
| BECALSKI, J; LAWKOWICZ, W | 1 |
| BORIO, DC; CASTELLANO, M; MACCOTTA, V | 1 |
| FAIELLA, A; PERRONE, V; ZARRILLI, D | 1 |
| BAYRD, ED | 1 |
| DACIE, JV; GALTON, DA; SZUR, L; WILTSHAW, E | 1 |
| PERSICO, L; PIACENTINI, G | 1 |
| PLIESS, G | 1 |
| GRUSHINA, AA; KRAVCHENKO, AI | 1 |
| LIBANSKY, J; TRAPL, J | 2 |
| KANDLER, T; WITTE, S | 1 |
| BARER, R; JOSEPH, S | 1 |
| BOYLAND, E; STAUNTON, MD; WILLIAMS, K | 1 |
| ELSON, LA; FLOERSHEIM, GL | 1 |
| FRIBORSKY, V; JELINEK, V; LOCHOVSKY, J | 1 |
| SPRAGUE, CC | 1 |
| AMBRUS, JL; BACK, N | 1 |
| BIERMAN, HR | 1 |
| SCOTT, JL | 1 |
| KOK, D | 1 |
| MOLANDER, DW | 1 |
| KOLFF, WJ; NAKAMOTO, S | 1 |
| EVANS, AM; RIEKHOF, P | 1 |
| ADAMS, JL | 1 |
| JURAND, A | 1 |
| KARNOFSKY, DA; MILLER, DG; PHILLIPS, RF | 1 |
| BROWN, EB; BURNINGHAM, RA; HARRINGTON, WJ; KHURI, PD; LESSNER, HE; PUGH, RP; RESTREPO, A; SCHLOSSMAN, SF | 1 |
| IGLESIAS, F; KOKAME, GM; KREMENTZ, ET | 1 |
| DIAMANDOPOULOS, GT; SMITH, EB | 1 |
| SULLI, G | 1 |
| EISMAN, SG; RICHARDSON, FM | 1 |
| TANIDA, T | 1 |
| STEEL, SJ | 1 |
| BARIETY, J; HESSE, JC; LAGRUE, G; MILLIEZ, P; SAFAR, M | 1 |
| FRECKMAN, HA; FRY, HL; MAURER, ER; MENDEZ, FL | 1 |
| CHUMAKOV, VM; SYRKIN, AB | 1 |
| PAPAC, RJ; WOOD, DA | 1 |
| ANDERSON, WR; HENDRY, WS; HUNEYCUTT, HC | 1 |
| KARNOFSKY, DA | 1 |
| HUTCHISON, JL | 1 |
| DONALDSON, SS; FLETCHER, WS | 1 |
| HRESCHCHYSHYN, MM | 1 |
| GUPTA, VS; HUENNEKENS, FM | 1 |
| BOLANDE, RP; SMITH, JC | 1 |
| DIXON, H; GREEN, RA | 1 |
| BLAKEMORE, WS; MCKENNA, JM; SANDERSON, RP | 1 |
| CRAVER, LF; DIAMOND, HD; MILLER, DG | 1 |
| PERISCO, L; PIACENTINI, G | 1 |
| PRADHAN, SN; WEST, WL | 1 |
| SAMPEY, JR | 1 |
| LINFORD, JH | 1 |
| BRENNER, SM; MILLER, SP | 1 |
| RABENKO, J | 1 |
| BONO, VH; CORLEY, CC; GRIZZLE, J; HUGULEY, CM; JONSSON, U; RUNDLES, W | 1 |
| Brahimi, F; Jean-Claude, BJ; Katsoulas, A; McNamee, J; Rachid, Z | 1 |
| Baron, A; Gunaratnam, M; Le Sann, C; Mann, J; Neidle, S; van den Berg, H | 1 |
| Balszuweit, F; Birtel, M; Burckhardt-Boer, W; Bürkle, A; Debiak, M; Lex, K; Mangerich, A; Martello, R; Ponath, V; Schmidt, A; Siegert, M; Steinritz, D; Strobelt, R; Thiermann, H | 1 |
| Garman, B; Glickson, JD; Leeper, DB; Nath, K; Nathanson, KL; Nelson, DS; Putt, ME | 1 |
| Gudermann, T; John, H; Kehe, K; Kranawetvogl, A; Lang, S; Popp, T; Rothmiller, S; Schmidt, A; Siegert, M; Steinritz, D; Thiermann, H | 1 |
20 review(s) available for mechlorethamine and chlorambucil
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Chemotherapy of the non-Hodgkin's lymphomas.
Topics: Antineoplastic Agents; Bleomycin; Chlorambucil; Cortisone; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Humans; Lymphoma; Mechlorethamine; Methotrexate; Streptonigrin; Vinblastine; Vincristine | 1976 |
Treatment of chronic lymphocytic leukemia.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Mechlorethamine; Prednisone; Splenectomy | 1977 |
Immunosuppressive agents in the treatment of the nephrotic syndrome and glomerulonephritis in children.
Topics: Azathioprine; Child; Chlorambucil; Cyclophosphamide; Glomerulonephritis; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Mechlorethamine; Nephritis; Nephrotic Syndrome; Proteinuria | 1979 |
Immunosuppressive therapy in the nephrotic syndrome in children.
Topics: Adrenal Cortex Hormones; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Cyclosporins; Glomerulosclerosis, Focal Segmental; Humans; Immunosuppressive Agents; Levamisole; Mechlorethamine; Nephrotic Syndrome; Platelet Aggregation Inhibitors | 1989 |
The sensitivity of Hodgkin's disease to chemotherapeutic agents administered singly.
Topics: Adrenal Cortex Hormones; Alopecia; Antineoplastic Agents; Bleomycin; Blood Platelet Disorders; Carmustine; Chlorambucil; Cyclophosphamide; Daunorubicin; Drug Evaluation; Drug Therapy, Combination; Hodgkin Disease; Humans; Leukopenia; Mechlorethamine; Mitolactol; Nervous System Diseases; Procarbazine; Remission, Spontaneous; Streptonigrin; Vinblastine; Vincristine | 1973 |
[Cytostatic chemotherapy in lymphogranulomatosis].
Topics: Antineoplastic Agents; Bleomycin; Carmustine; Chlorambucil; Cyclohexanes; Cyclophosphamide; Doxorubicin; Drug Combinations; Hodgkin Disease; Humans; Mechlorethamine; Nitrosourea Compounds; Procarbazine; Prognosis; Splenectomy; Vinblastine; Vincristine | 1973 |
[Indications for immunosuppressive treatment in kidney diseases of children].
Topics: Alkylating Agents; Anti-Bacterial Agents; Antimetabolites; Antineoplastic Agents; Azathioprine; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Glomerulonephritis; Humans; Immunosuppressive Agents; Mechlorethamine; Mercaptopurine; Methotrexate | 1969 |
A review of chemotherapy in gastric cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Carmustine; Chlorambucil; Chromomycins; Cyclophosphamide; Cytarabine; Drug Evaluation; Drug Therapy, Combination; Floxuridine; Fluorouracil; Humans; Mechlorethamine; Methotrexate; Mitomycins; Nitrosourea Compounds; Olivomycins; Stomach Neoplasms | 1974 |
Cancer chemotherapy. I.
Topics: Animals; Busulfan; Chlorambucil; Cyclophosphamide; Female; Humans; Male; Mechlorethamine; Melphalan; Methotrexate; Mice; Neoplasms; Thiotepa | 1972 |
Single-agent therapy for Hodgkin's disease.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Carmustine; Chlorambucil; Cyclophosphamide; Dactinomycin; Evaluation Studies as Topic; Fluorouracil; Hodgkin Disease; Humans; Mechlorethamine; Mercaptopurine; Methotrexate; Prednisone; Procarbazine; Thiotepa; Vinblastine; Vincristine | 1973 |
Immunosuppressive drugs in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Cyclophosphamide; Female; Humans; Immunosuppressive Agents; Mechlorethamine; Mercaptopurine; Methotrexate; Prednisolone; Pregnancy | 1969 |
The therapy of lymphoma.
Topics: Adrenal Cortex Hormones; Asparaginase; Bone Marrow Diseases; Chlorambucil; Cyclophosphamide; Cytarabine; Daunorubicin; Fever; Humans; Hydrazines; Infections; Kidney Failure, Chronic; Lymphoma; Mechlorethamine; Splenectomy; Vinblastine; Vincristine | 1969 |
Treatment of rheumatoid arthritis with cytotoxic and antimetabolic drugs.
Topics: Alopecia; Aminopterin; Antimetabolites; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Bone Marrow Diseases; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Cystitis; Female; Herpes Zoster; Humans; Jaundice; Mechlorethamine; Mercaptopurine; Methotrexate | 1970 |
Immunosuppressant agents in the treatment of glomerulonephritis. 2. Cytotoxic drugs.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Antilymphocyte Serum; Antineoplastic Agents; Azathioprine; Child; Chlorambucil; Creatinine; Cyclophosphamide; Drug Antagonism; Drug Hypersensitivity; Glomerulonephritis; Granulomatosis with Polyangiitis; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Mechlorethamine; Prednisolone; Proteinuria; Purpura; Recurrence; Remission, Spontaneous | 1971 |
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Mechlorethamine; Mercaptopurine; Methotrexate; Procarbazine; Vinblastine | 1980 |
DNA damage and mutagenesis induced by nitrogen mustards.
Topics: Animals; Base Sequence; Chlorambucil; Cyclophosphamide; DNA; DNA Damage; DNA Repair; Humans; Mechlorethamine; Melphalan; Molecular Sequence Data; Mutagenesis; Nitrogen Mustard Compounds; Phosphoramide Mustards | 1994 |
Chlorambucil drug resistance in chronic lymphocytic leukemia: the emerging role of DNA repair.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Biological Transport; Chlorambucil; Cross-Linking Reagents; DNA Repair; Drug Resistance, Neoplasm; Genes, p53; Glutathione; Glutathione Transferase; Leukemia, Lymphocytic, Chronic, B-Cell; Mechlorethamine; Models, Genetic; Mutation; Recombination, Genetic | 2001 |
Is escalated BEACOPP a standard therapy for advanced Hodgkin's disease?
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Clinical Trials, Phase III as Topic; Cyclophosphamide; Dacarbazine; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Hodgkin Disease; Humans; Infertility; Mechlorethamine; Prednisolone; Prednisone; Procarbazine; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Safety; Treatment Outcome; Vinblastine; Vincristine | 2000 |
[MEDICAL THERAPY OF MALIGNANT NEOPLASMS].
Topics: Antimetabolites; Antineoplastic Agents; Antiviral Agents; Blood Transfusion; Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Diet; Diet Therapy; Estrogens; Female; Iodine Isotopes; Mechlorethamine; Methotrexate; Neoplasms; Phosphorus Isotopes; Prednisone; Pregnancy; Pregnancy Complications; Progesterone; Testosterone; Triethylenemelamine; Vinblastine; Vitamins | 1964 |
15 trial(s) available for mechlorethamine and chlorambucil
| Article | Year |
|---|---|
Clinical trials with BCNU (NSC-409962) in malignant lymphomas by the Eastern Cooperative Oncology Group.
Topics: Bleomycin; Carmustine; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Mechlorethamine; Prednisone; Procarbazine; Prospective Studies; Vincristine | 1976 |
Lymphosarcoma. A comparison of extended to conservative chemotherapy.
Topics: Adult; Aged; Carmustine; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Lymphoma, Non-Hodgkin; Male; Mechlorethamine; Middle Aged; Prednisone; Remission, Spontaneous; Vincristine | 1976 |
British National Lymphoma Investigation randomised study of MOPP (mustine, Oncovin, procarbazine, prednisolone) against LOPP (Leukeran substituted for mustine) in advanced Hodgkin's disease--long term results.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; Follow-Up Studies; Hodgkin Disease; Humans; Male; Mechlorethamine; Middle Aged; Multivariate Analysis; Neoplasms; Prednisolone; Prednisone; Procarbazine; Prognosis; Remission Induction; Vincristine | 1991 |
[Low-grade non-Hodgkin's lymphoma in the adult: new therapeutic approaches].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; Humans; Interferons; Lymphoma, Non-Hodgkin; Mechlorethamine; Prednisone; Procarbazine; Vincristine | 1987 |
Treatment with MOPP or ChlVPP chemotherapy only for all stages of childhood Hodgkin's disease.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chlorambucil; Clinical Trials as Topic; Female; Hodgkin Disease; Humans; Male; Mechlorethamine; Neoplasm Staging; Prednisolone; Prednisone; Procarbazine; Vinblastine; Vincristine | 1988 |
Randomised study of MOPP (mustine, Oncovin, procarbazine, prednisone) against LOPP (Leukeran substituted for mustine) in advanced Hodgkin's disease. British National Lymphoma Investigation.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials as Topic; Female; Follow-Up Studies; Hodgkin Disease; Humans; Male; Mechlorethamine; Middle Aged; Neoplasm Staging; Prednisone; Procarbazine; Random Allocation; Vincristine | 1986 |
Chemotherapy of Hodgkin's disease in studies by acute leukemia group B.
Topics: Antineoplastic Agents; Carmustine; Chlorambucil; Evaluation Studies as Topic; Hodgkin Disease; Humans; Mechlorethamine; Prednisone; Procarbazine; Vinblastine; Vincristine | 1973 |
Mechlorethamine HCl and cyclophosphamide in the treatment of Hodgkin's disease and the lymphomas.
Topics: Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Dosage Forms; Follow-Up Studies; Hodgkin Disease; Humans; Injections, Intravenous; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine | 1968 |
Treatment of rheumatoid arthritis with cytotoxic and antimetabolic drugs.
Topics: Alopecia; Aminopterin; Antimetabolites; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Bone Marrow Diseases; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Cystitis; Female; Herpes Zoster; Humans; Jaundice; Mechlorethamine; Mercaptopurine; Methotrexate | 1970 |
Chemotherapeutic implications of staging in Hodgkin's disease.
Topics: Animals; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Combinations; Follow-Up Studies; Hodgkin Disease; Humans; Leukemia L1210; Mechlorethamine; Procarbazine; Vinblastine | 1971 |
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Mechlorethamine; Mercaptopurine; Methotrexate; Procarbazine; Vinblastine | 1980 |
Combination chemotherapy for stage IV Hodgkin's disease (Report no 14).
Topics: Bleomycin; Chlorambucil; Drug Therapy, Combination; Hodgkin Disease; Humans; Mechlorethamine; Neoplasm Staging; Prednisone; Procarbazine; Vincristine | 1981 |
Radiotherapy or chemotherapy as the initial treatment for stage IIIA Hodgkin's disease (Report no 13).
Topics: Chlorambucil; Drug Therapy, Combination; Hodgkin Disease; Humans; Laparotomy; Mechlorethamine; Neoplasm Staging; Prednisone; Procarbazine; Splenic Neoplasms; Vincristine | 1981 |
Results of a randomized trial comparing MVPP chemotherapy with a hybrid regimen, ChlVPP/EVA, in the initial treatment of Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Disease-Free Survival; Doxorubicin; Etoposide; Female; Follow-Up Studies; Hodgkin Disease; Humans; Male; Mechlorethamine; Middle Aged; Prednisolone; Procarbazine; Remission Induction; Survival Rate; Vinblastine; Vincristine | 1995 |
Gonadal function following chemotherapy for Hodgkin's disease: a comparative study of MVPP and a seven-drug hybrid regimen.
Topics: Adolescent; Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Doxorubicin; Etoposide; Female; Follicle Stimulating Hormone; Hodgkin Disease; Humans; Libido; Luteinizing Hormone; Male; Mechlorethamine; Menstrual Cycle; Middle Aged; Prednisolone; Primary Ovarian Insufficiency; Procarbazine; Prospective Studies; Semen; Sex Hormone-Binding Globulin; Sperm Count; Testis; Testosterone; Vinblastine; Vincristine | 1995 |
190 other study(ies) available for mechlorethamine and chlorambucil
| Article | Year |
|---|---|
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Congenital anomalies among children born of mothers receiving chemotherapy for gestational trophoblastic neoplasms.
Topics: Abnormalities, Drug-Induced; Antineoplastic Agents; Chlorambucil; Drug Therapy, Combination; Female; Humans; Mechlorethamine; Methotrexate; Placenta Accreta; Pregnancy; Pregnancy Complications; Trophoblastic Neoplasms; Uterine Neoplasms; Vinblastine | 1976 |
Formation and fate of cross-links induced by polyfunctional anticancer drugs in yeast.
Topics: Alkylation; Chlorambucil; Cross-Linking Reagents; DNA; DNA, Single-Stranded; Kinetics; Mechlorethamine; Nucleic Acid Renaturation; Saccharomyces cerevisiae; Triaziquone | 1979 |
[Chemotherapy of the ovarian carcinoma (author's transl)].
Topics: Altretamine; Antineoplastic Agents; Chlorambucil; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hydroxyprogesterones; Mechlorethamine; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Nitrosourea Compounds; Ovarian Neoplasms; Thiotepa; Vinblastine; Vincristine | 1977 |
Residual marrow injury following cytotoxic drugs.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Chlorambucil; Dacarbazine; Doxorubicin; Female; Granulocytes; Hematopoietic Stem Cells; Mechlorethamine; Melphalan; Mice; Mice, Inbred BALB C; Mitomycins | 1979 |
Childhood embryonal carcinoma of testis, report of two unusual cases, and the implication on clinical management.
Topics: Castration; Child, Preschool; Chlorambucil; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Infant; Lung Neoplasms; Male; Mechlorethamine; Neoplasm Metastasis; Radiotherapy Dosage; Teratoma; Testicular Neoplasms; Testis; Vincristine | 1978 |
Comparison of different methods of determining cell viability after exposure to cytotoxic compounds.
Topics: Amphotericin B; Antibiotics, Antineoplastic; Antineoplastic Agents; Carmustine; Cell Adhesion; Cell Line; Cell Survival; Chlorambucil; Cytarabine; Cytological Techniques; Doxorubicin; Mechlorethamine; Nogalamycin; Pactamycin; Tubercidin; Vincristine | 1976 |
Treatment of lupus nephritis.
Topics: Adrenal Cortex Hormones; Adult; Animals; Antibody Formation; Azathioprine; Chlorambucil; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glomerulonephritis; Humans; Lupus Erythematosus, Systemic; Male; Mechlorethamine; Methylprednisolone; Mice; Mice, Inbred NZB; Middle Aged; Prednisone | 1976 |
Thrombocythemia, thrombocytosis.
Topics: Administration, Oral; Blood Cell Count; Blood Platelets; Chlorambucil; Emergencies; Humans; Mechlorethamine; Phosphorus Radioisotopes; Thrombocytosis | 1976 |
The role of drug transport in resistance to nitrogen mustard and other alkylating agents in L518Y lymphoblsts.
Topics: Alkylating Agents; Animals; Binding, Competitive; Biological Transport; Carmustine; Cell Line; Chlorambucil; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Resistance; Female; Leukemia, Experimental; Leukemia, Lymphoid; Male; Mechlorethamine; Melphalan; Mice; Mice, Inbred DBA; Mitomycins | 1975 |
Towards curative treatment of advanced Hodgkin's disease.
Topics: Chlorambucil; Drug Therapy, Combination; Hodgkin Disease; Humans; Mechlorethamine; Prednisone; Procarbazine; Remission, Spontaneous; Vinblastine; Vincristine | 1975 |
The interaction of bifunctional alkylating agents with the DNA of tumour cells.
Topics: Alkylating Agents; Animals; Chlorambucil; DNA Repair; DNA, Neoplasm; In Vitro Techniques; Mechlorethamine; Nitrogen Mustard Compounds; Rats; Sarcoma, Yoshida | 1976 |
Hodgkin's disease and acute leukemia. Is it a true association?
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy; Female; Follow-Up Studies; Hodgkin Disease; Humans; Immunity, Innate; Leukemia; Leukemia, Radiation-Induced; Male; Mechlorethamine; Mexico; Middle Aged; Neoplasms, Second Primary; Nitrosourea Compounds; Prednisone; Procarbazine; Radiotherapy; Remission Induction; Salvage Therapy; Vincristine | 1992 |
[Neurectodermal malignant tumor of the soft tissues after treatment with immunosuppressive agents of lipoid nephrosis].
Topics: Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Follow-Up Studies; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Male; Mechlorethamine; Nephrosis, Lipoid; Sarcoma, Ewing; Soft Tissue Neoplasms; Vincristine | 1992 |
Risk of second primary cancers after Hodgkin's disease by type of treatment: analysis of 2846 patients in the British National Lymphoma Investigation.
Topics: Adolescent; Adult; Alkylating Agents; Child; Chlorambucil; Cohort Studies; Female; Follow-Up Studies; Hodgkin Disease; Humans; Male; Mechlorethamine; Neoplasms, Second Primary; Radiotherapy; Risk; Risk Factors; Time Factors; United Kingdom | 1992 |
Nitrogen mustard-DNA interaction in melphalan-resistant mammary carcinoma cells with elevated intracellular glutathione and glutathione-S-transferase activity.
Topics: Animals; Buthionine Sulfoximine; Cell Division; Cell Survival; Chlorambucil; DNA; Drug Interactions; Drug Resistance; Glutathione; Glutathione Transferase; Mammary Neoplasms, Experimental; Mechlorethamine; Melphalan; Methionine Sulfoximine; Rats; RNA, Messenger; Tumor Cells, Cultured | 1992 |
Thermolabile adenine adducts and A.T base pair substitutions induced by nitrogen mustard analogues in an SV40-based shuttle plasmid.
Topics: Adenine Nucleotides; Alkylating Agents; Base Composition; Base Sequence; Chlorambucil; Genetic Vectors; Hot Temperature; Mechlorethamine; Melphalan; Molecular Sequence Data; Mutagenesis; Plasmids; Simian virus 40; Thymine Nucleotides | 1991 |
Hodgkin's disease of the liver; prognosis and possible indications for radiotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Protocols; Hodgkin Disease; Humans; Liver; Liver Neoplasms; Mechlorethamine; Neoplasm Staging; Prednisolone; Procarbazine; Prognosis; Radiotherapy Dosage; Remission Induction; Retrospective Studies; Time Factors; Vinblastine | 1991 |
DNA adenine adducts induced by nitrogen mustards and their role in transcription termination in vitro.
Topics: Amino Acid Sequence; Chlorambucil; DNA; DNA Damage; Genes, myc; Mechlorethamine; Melphalan; Molecular Sequence Data; Templates, Genetic; Transcription, Genetic | 1990 |
Transcription-terminating lesions induced by bifunctional alkylating agents in vitro.
Topics: Alkylating Agents; Alkylation; Base Sequence; Chlorambucil; Cyclophosphamide; DNA; DNA Damage; Exons; Genetic Vectors; Guanine; Humans; Mechlorethamine; Melphalan; Molecular Sequence Data; Plasmids; Proto-Oncogenes; Templates, Genetic; Transcription, Genetic | 1989 |
Chlorambucil, vinblastine, procarbazine, and prednisone. An effective but less toxic regimen than MOPP for advanced-stage Hodgkin's disease.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Chlorambucil; Female; Hodgkin Disease; Humans; Male; Mechlorethamine; Middle Aged; Neoplasm Staging; Neutropenia; Prednisolone; Prednisone; Procarbazine; Recurrence; Remission Induction; Vinblastine; Vincristine | 1989 |
Central nervous system vasculitis in Behçet's syndrome: angiographic improvement after therapy with cytotoxic agents.
Topics: Adult; Antineoplastic Agents; Behcet Syndrome; Cerebral Angiography; Cerebrovascular Disorders; Chlorambucil; Female; Humans; Mechlorethamine; Prednisone | 1989 |
Functional properties in Sézary cells with an unusual phenotype.
Topics: Aged; Antibodies, Monoclonal; Chlorambucil; Dermatitis, Exfoliative; Drug Therapy, Combination; Humans; Killer Cells, Natural; Lymphocyte Activation; Lymphocytes; Male; Mechlorethamine; Mycosis Fungoides; Phenotype; Prednisone; Recurrence; Sezary Syndrome; Thymus Extracts | 1985 |
Plasma membrane as target of alkylating agents.
Topics: Adenosine Triphosphatases; Alkylating Agents; Animals; Calcium Channel Blockers; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Cell Division; Cell Line; Cell Membrane; Cells, Cultured; Chlorambucil; DNA; Mechlorethamine; Potassium; Quinacrine | 1985 |
Differential sensitivity of histone acetylation in nitrogen-mustard sensitive and resistant cells. Relation to drug uptake, formation and repair of DNA-interstrand cross-links.
Topics: Acetylation; Animals; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Chlorambucil; Cyclophosphamide; DNA; Drug Resistance; Histones; Mechlorethamine; Rats; Tumor Cells, Cultured | 1988 |
ChlVPP--an effective and well-tolerated alternative to MOPP therapy for Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; Hodgkin Disease; Humans; Male; Mechlorethamine; Middle Aged; Prednisolone; Prednisone; Procarbazine; Vinblastine; Vincristine | 1988 |
Glutathione S-transferases in nitrogen mustard-resistant and -sensitive cell lines.
Topics: Alkylating Agents; Animals; Carcinoma 256, Walker; Chlorambucil; Cytosol; Drug Resistance; Glutathione Transferase; Mechlorethamine; Molecular Weight; Rats; Substrate Specificity | 1987 |
Minimal change nephrotic syndrome and cyclophosphamide.
Topics: Child; Chlorambucil; Cyclophosphamide; Humans; Mechlorethamine; Nephrosis, Lipoid | 1986 |
Purpura fulminans in pneumococcal sepsis.
Topics: Acute Kidney Injury; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; Gangrene; Hodgkin Disease; Humans; Immunoglobulin G; Lymphoma; Mechlorethamine; Pneumococcal Infections; Prednisone; Procarbazine; Purpura; Splenectomy; Vincristine | 1986 |
Chemotherapy treated Hodgkins disease--a fifteen year review.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; Follow-Up Studies; Hodgkin Disease; Humans; Male; Mechlorethamine; Prednisone; Procarbazine; Vinblastine; Vincristine | 1986 |
Chronic lymphocytic leukemia: a study of 53 patients and review of the literature.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy; Female; Humans; Leukemia, Lymphoid; Male; Mechlorethamine; Middle Aged; Prednisolone; Prednisone; Procarbazine; Prognosis; Puerto Rico; Sex Factors; Vincristine | 1985 |
Risk of acute nonlymphocytic leukemia and preleukemia in patients treated with cyclophosphamide for non-Hodgkin's lymphomas. Comparison with results obtained in patients treated for Hodgkin's disease and ovarian carcinoma with other alkylating agents.
Topics: Acute Disease; Adolescent; Adult; Aged; Alkylating Agents; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Chlorambucil; Combined Modality Therapy; Cyclophosphamide; Female; Follow-Up Studies; Hodgkin Disease; Humans; Infant; Leukemia; Lymphoma; Male; Mechlorethamine; Middle Aged; Myeloproliferative Disorders; Nitrosourea Compounds; Ovarian Neoplasms; Preleukemia; Risk; Time Factors | 1985 |
Treatment of lupus nephritis with cyclophosphamide.
Topics: Adolescent; Adult; Age Factors; Azathioprine; Biopsy; Chlorambucil; Cortisone; Cyclophosphamide; Female; Glomerulonephritis; Humans; Kidney; Leukopenia; Lupus Erythematosus, Systemic; Male; Mechlorethamine; Mercaptopurine; Prednisolone; Proteinuria; Racial Groups; Serum Albumin; Sex Factors; Thioguanine | 1970 |
Acute leukemia in Hodgkin's disease.
Topics: Adult; Bleomycin; Carmustine; Chlorambucil; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Male; Mechlorethamine; Middle Aged; Neoplasms, Multiple Primary; Prednisone; Procarbazine; Time Factors; Vinblastine | 1974 |
Prognosis and survival with extranodal Hodgkin's disease.
Topics: Adult; Carmustine; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Hodgkin Disease; Humans; Mechlorethamine; Palliative Care; Prednisone; Procarbazine; Prognosis; Recurrence; Retrospective Studies; Time Factors; Vinblastine; Vinca Alkaloids; Vincristine | 1974 |
[Detection of a moderate staphylococcal phage by means of antineoplastic agents].
Topics: Aminopterin; Antibiotics, Antineoplastic; Anticholesteremic Agents; Antimetabolites; Antineoplastic Agents; Chlorambucil; Colchicine; Cyclophosphamide; Dactinomycin; Drug Resistance, Microbial; Flavonoids; Fluorouracil; Lysogeny; Mechlorethamine; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Olivomycins; Staphylococcus; Staphylococcus Phages; Thiotepa; Ultraviolet Rays; Uracil; Vinblastine; Vincristine | 1970 |
[Hodgkin's disease in the practice of general medicine. Problems posed by the diagnosis, surveillance of treatments and social rehabilitation of patients].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Biopsy; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Laparotomy; Mechlorethamine; Procarbazine; Rehabilitation, Vocational; Splenectomy; Thiotepa; Vinblastine; Vincristine | 1974 |
Synergistic lethal action of alkylating agents and sodium pentobarbital in the mouse.
Topics: Alkylating Agents; Animals; Atropine; Chlorambucil; Cyclophosphamide; Decamethonium Compounds; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Hexamethonium Compounds; Injections, Intraperitoneal; Injections, Intravenous; Lethal Dose 50; Male; Mechlorethamine; Melphalan; Mice; Pentobarbital; Thiotepa; Time Factors | 1974 |
Chemotherapy of testicular germinal tumors.
Topics: Alkylating Agents; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Dactinomycin; Dysgerminoma; Humans; Male; Mechlorethamine; Melphalan; Methotrexate; Nitrofurazone; Pharmaceutic Aids; Plicamycin; Prognosis; Testicular Neoplasms; Testis; Vincristine | 1973 |
[Prevention of experimental allergic encephalomyelitis by immunological technics].
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Chlorambucil; Cortisone; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Immune Tolerance; Immunosuppressive Agents; Mechlorethamine; Mercaptopurine; Methotrexate | 1968 |
On the neurotoxic effects induced by alkylating agents.
Topics: Alanine; Animals; Anti-Bacterial Agents; Antimetabolites; Azaserine; Behavior, Animal; Central Nervous System; Chlorambucil; Cyclophosphamide; Cysteine; Drug Antagonism; Glycine; Male; Mannitol; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Phenobarbital; Phenytoin; Rats; Seizures; Spasm; Thiourea; Triethylenemelamine; Tryptophan | 1966 |
Reticulum cell sarcoma. A review of radiotherapeutic experience.
Topics: Adolescent; Adult; Aged; Chlorambucil; Female; Follow-Up Studies; Humans; Lymphoma, Non-Hodgkin; Male; Mechlorethamine; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Radiotherapy; Radiotherapy Dosage | 1972 |
[Nephropathies of rheumatoid purpura in children. Clinical and anatomical study of 60 cases].
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Diagnosis, Differential; Female; Fluorescent Antibody Technique; Glomerulonephritis; Hematuria; Humans; Kidney Glomerulus; Male; Mechlorethamine; Mercaptopurine; Nephrotic Syndrome; Proteinuria; Purpura | 1972 |
Nephrosis of Hodgkin disease. An immune complex-induced lesion.
Topics: Antigen-Antibody Complex; Basement Membrane; Biopsy; Blood Urea Nitrogen; Body Weight; Capillaries; Chlorambucil; Fluorescent Antibody Technique; Hodgkin Disease; Humans; Immunoglobulins; Kidney Glomerulus; Male; Mechlorethamine; Microscopy, Electron; Middle Aged; Nephrotic Syndrome; Proteinuria; Serum Albumin; Vinblastine | 1973 |
Survival of hematopoietic and lymphoma colony-forming cells in vivo following the administration of a variety of alkylating agents.
Topics: Alkylating Agents; Animals; Cell Line; Cell Survival; Chlorambucil; Clone Cells; Cyclophosphamide; Female; Hematopoietic Stem Cells; Lethal Dose 50; Lymphoma; Mechlorethamine; Melphalan; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Nitrosourea Compounds; Thiotepa; Triethylenemelamine | 1972 |
The treatment of Hodgkin's disease.
Topics: Agranulocytosis; Antineoplastic Agents; Bone Marrow Diseases; Chlorambucil; Drug Combinations; Hodgkin Disease; Humans; Mechlorethamine; Prednisone; Procarbazine; Prognosis; Radiotherapy Dosage; Remission, Spontaneous; Vinblastine; Vincristine | 1972 |
Bioassay and relative cytotoxic potency of cyclophosphamide metabolites generated in vitro and in vivo.
Topics: Acrolein; Animals; Biological Assay; Carcinoma 256, Walker; Cell Survival; Chlorambucil; Cyclophosphamide; Injections, Intraperitoneal; Male; Mechlorethamine; Microsomes, Liver; Neoplasm Transplantation; Phenobarbital; Rats; Transplantation, Homologous | 1973 |
Effects of antileukemic agents on the respiratory activity of murine lymphocytic Leukemia L1210.
Topics: Animals; Buffers; Busulfan; Cell Adhesion; Cell Survival; Chlorambucil; Cyclophosphamide; Cytoplasm; Depression, Chemical; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Lethal Dose 50; Leukemia L1210; Mechlorethamine; Mice; Microscopy, Electron; Mitochondria; Nitrogen Mustard Compounds; Nitrosourea Compounds; Oxygen Consumption | 1973 |
Combined drug treatment of Hodgkin's disease: remission induction, remission duration, and survival; an appraisal.
Topics: Adult; Age Factors; Antineoplastic Agents; Biopsy; Carmustine; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Evaluation Studies as Topic; Follow-Up Studies; Hodgkin Disease; Humans; Mechlorethamine; Middle Aged; Prednisone; Procarbazine; Remission, Spontaneous; Time Factors; Vinblastine; Vincristine | 1973 |
Oxymetholone in the chemotherapy of malignant disease.
Topics: Administration, Oral; Blood Cell Count; Blood Platelets; Bone Marrow; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Female; Hemoglobinometry; Humans; Leukocyte Count; Mechlorethamine; Mercaptopurine; Neoplasms; Oxymetholone; Prednisolone; Prognosis; Time Factors; Vinblastine; Vincristine | 1973 |
The effects of antineoplastic agents on the respiratory activity of murine lymphocytic leukemia L1210.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Chlorambucil; Dactinomycin; Dose-Response Relationship, Drug; Leukemia L1210; Mechlorethamine; Mercaptopurine; Methotrexate; Mice; Oxygen Consumption; Prednisone; Vinblastine | 1973 |
[Recovery of normal ultrastructure in 2 cases of primary glomerulonephritis with diffuse extra-membranous deposits].
Topics: Adult; Basement Membrane; Biopsy; Chlorambucil; Female; Glomerulonephritis; Glucocorticoids; Hematuria; Histological Techniques; Humans; Hypertension, Renal; Immunosuppressive Agents; Kidney Glomerulus; Male; Mechlorethamine; Mercaptopurine; Methods; Microscopy, Electron; Middle Aged; Nephrotic Syndrome; Prednisone; Prognosis; Proteinuria; Silver | 1968 |
Nonhuman primates in evaluation of hematotoxicity.
Topics: Animals; Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug-Related Side Effects and Adverse Reactions; Folic Acid Antagonists; Haplorhini; Hematologic Diseases; Hematopoiesis; Infections; Leukocyte Count; Leukopenia; Mechlorethamine; Mercaptopurine; Models, Biological; Pyrimidines; Thiotepa; Triethylenemelamine; Vinblastine; Vincristine | 1969 |
[Results and current biological bases of therapy of malignant hemoreticulopathies].
Topics: Antineoplastic Agents; Chlorambucil; Cortisone; Cyclophosphamide; Humans; Hydrazines; Leukemia; Lymphoma; Mechlorethamine; Methotrexate; Plasmacytoma; Polycythemia; Vinblastine; Waldenstrom Macroglobulinemia | 1971 |
[Hodgkin's disease].
Topics: Adolescent; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Chlorambucil; Cyclophosphamide; Female; Hodgkin Disease; Humans; Male; Mechlorethamine; Middle Aged; Peptides; Prednisolone | 1971 |
[Mycosis fungoides. A form of pleuropulmonary origin with cutaneous sclerodermiform manifestations. Treatment by application of nitrogen mustard].
Topics: Chlorambucil; Cortisone; Humans; Male; Mechlorethamine; Middle Aged; Mycosis Fungoides; Skin Neoplasms | 1971 |
Recent advances in chemotherapy of lymphoma.
Topics: Alkylating Agents; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Vinblastine; Vincristine | 1967 |
[Chemotherapy of malignant lymphomas].
Topics: Adrenal Cortex Hormones; Amines; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Hydrazines; Lymphoma; Mechlorethamine; Vinblastine; Vincristine | 1970 |
Evidence for a transport carrier of nitrogen mustard in nitrogen mustard-sensitive and -resistant L5178Y lymphoblasts.
Topics: Biological Transport, Active; Carbon Isotopes; Cell Line; Chlorambucil; Culture Techniques; Cyclophosphamide; Kinetics; Lymphocytes; Mechlorethamine; Melphalan; Nitrophenols; Ouabain; Protein Binding | 1970 |
Factors determining cell killing by chemotherapeutic agents in vivo. II. Melphalan, chlorambucil and nitrogen mustard.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Survival; Chlorambucil; Cyclophosphamide; DNA; Female; Hematopoietic Stem Cells; Male; Mechlorethamine; Melphalan; Mice; Spleen | 1971 |
Chemotherapy of Hodgkin's disease, lymphoma, and leukemia.
Topics: Adult; Antineoplastic Agents; Busulfan; Chlorambucil; Hodgkin Disease; Humans; Leukemia; Lymphoma; Male; Mechlorethamine; Melphalan; Vinblastine | 1968 |
Growth inhibitory and haematological effects of alkylating agents and attempts at their modification to give greater selectivity of anti-tumour action.
Topics: Alkylating Agents; Animals; Body Weight; Carcinoma 256, Walker; Chemical Phenomena; Chemistry; Chlorambucil; Cysteine; Hematopoiesis; Mechlorethamine; Mice; Mitosis; Neoplasms, Experimental; Rats | 1968 |
Endobronchial presentation of malignant lymphoma.
Topics: Bone Neoplasms; Bronchial Neoplasms; Bronchoscopy; Chlorambucil; Hodgkin Disease; Humans; Male; Mechlorethamine; Middle Aged; Neoplasm Metastasis; Scapula; Skull; Steroids; Thoracic Neoplasms | 1968 |
[Hepatotoxicity of antimitotic treatments. Effect of hepatic tests].
Topics: Adolescent; Adult; Animals; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Chlorambucil; Cyclophosphamide; Female; Humans; Liver Function Tests; Male; Mechlorethamine; Mercaptopurine; Methotrexate; Middle Aged; Mitomycins; Neoplasms; Rats; Urethane; Vinblastine; Vincristine | 1968 |
[Attempt at treatment of idiopathic nephrotic syndrome in children by brief cortisone therapy eventually alternated with an immunodepressor therapy].
Topics: Adolescent; Age Factors; Child; Child, Preschool; Chlorambucil; Drug Synergism; Female; Humans; Male; Mechlorethamine; Nephrotic Syndrome; Periodicity; Time Factors | 1968 |
[Results of immunosuppressive treatment of diseases of renal glomerulus in children].
Topics: Azathioprine; Child; Child, Preschool; Chlorambucil; Chronic Disease; Female; Glomerulonephritis; Humans; Immunosuppressive Agents; Infant; Male; Mechlorethamine; Mercaptopurine; Nephrosis, Lipoid | 1969 |
[Attempts of the use of cytostatic agents in some forms of glomerulonephritis in children].
Topics: Adolescent; Antineoplastic Agents; Azathioprine; Child; Child, Preschool; Chlorambucil; Chronic Disease; Female; Glomerulonephritis; Humans; Male; Mechlorethamine; Mercaptopurine; Nephrotic Syndrome | 1969 |
[Extended chemotherapy of nephrotic syndromes and of certain glomerular nephropathies].
Topics: Chlorambucil; Glomerulonephritis; Humans; Mechlorethamine; Nephrotic Syndrome | 1965 |
Advanced Hodgkin's disease. Management with chemotherapeutic agents.
Topics: Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Hydrazines; Mechlorethamine; Prednisone; Vinblastine | 1965 |
Ewing's sarcoma a study of treatment methods.
Topics: Adolescent; Bone Neoplasms; Child; Chlorambucil; Cyclophosphamide; Female; Humans; Male; Mechlorethamine; Methotrexate; Neoplasm Metastasis; Sarcoma, Ewing | 1966 |
X-radiation and alkylating agents as possible "trigger" mechanisms in the autoimmune complications of malignant lymphophroliferative disease.
Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Chlorambucil; Humans; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Male; Mechlorethamine; Middle Aged; Phosphorus Isotopes; Purpura, Thrombocytopenic; Radiation Injuries; Triethylenemelamine; Vascular Diseases | 1966 |
Reaction mechanism of some aromatic nitrogen mustards.
Topics: Azirines; Chemical Phenomena; Chemistry; Chlorambucil; Kinetics; Mechlorethamine; Melphalan; Mercaptoethanol; Solutions | 1967 |
Reaction of bifunctional alkylating agents with tetrahydrofolate.
Topics: Alkylating Agents; Carbon Isotopes; Cellulose; Chlorambucil; Chromatography; Chromatography, Paper; Folic Acid; Hydrogen-Ion Concentration; Mechlorethamine; Oxidation-Reduction; Spectrophotometry; Temperature | 1967 |
Hypersensitivity to nitrogen mustards in the form of erythema multiforme. A unique adverse reaction.
Topics: Chlorambucil; Drug Hypersensitivity; Erythema Multiforme; Hodgkin Disease; Humans; Male; Mechlorethamine; Middle Aged; Prednisone; Skin | 1967 |
Chromosome changes in embryos treated with various teratogens.
Topics: Abnormalities, Drug-Induced; Animals; Chlorambucil; Chromosome Aberrations; Diet; Female; Hydroxyurea; Mechlorethamine; Mitosis; Nitrogen Mustard Compounds; Pregnancy; Rabbits; Rats; Streptonigrin; Thalidomide | 1967 |
Action of elatericin A on human leukemic and normal lymphocytes.
Topics: Aminopterin; Animals; Antineoplastic Agents; Azirines; Cathartics; Cell Nucleus; Chlorambucil; Cyclophosphamide; Female; Hodgkin Disease; Humans; In Vitro Techniques; Leukemia, Lymphoid; Lymphocytes; Lymphoma, Non-Hodgkin; Male; Mechlorethamine; Mice; Middle Aged; Plants; Resins, Plant; Urethane | 1967 |
Chemotherapy of Hodgkin's disease.
Topics: Antineoplastic Agents; Bleomycin; Chlorambucil; Drug Administration Schedule; Drug Therapy, Combination; Hodgkin Disease; Humans; Mechlorethamine; Methotrexate; Prednisolone; Procarbazine; Remission, Spontaneous; Time Factors; Vinblastine; Vincristine | 1980 |
[Effect of mechlorethamine in idiopathic nephrotic syndrome in childhood].
Topics: Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Drug Tolerance; Female; Glomerulosclerosis, Focal Segmental; Humans; Male; Mechlorethamine; Nephrosis, Lipoid; Nephrotic Syndrome; Prednisone; Recurrence | 1984 |
Comparison of treatments for symptomatic Hodgkin's lymphoma employing decision analysis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Decision Making; Health Services Research; Hodgkin Disease; Humans; Internship and Residency; Male; Mechlorethamine; Medical Oncology; Models, Theoretical; Neoplasm Staging; Prednisolone; Prednisone; Probability; Procarbazine; Vinblastine; Vincristine | 1984 |
[Testicular damage caused by chemotherapy in acute lymphoblastic leukemia].
Topics: Adolescent; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Chlorambucil; Cyclophosphamide; Humans; Leukemia, Lymphoid; Male; Mechlorethamine; Mice; Oligospermia; Prednisone; Procarbazine; Spermatogenesis; Testis; Vincristine | 1983 |
Alkylation of guanosine by phosphoramide mustard, chloromethine hydrochloride and chlorambucil.
Topics: Alkylation; Chlorambucil; Chromatography, High Pressure Liquid; Drug Stability; Guanosine; Mechlorethamine; Phosphoramide Mustards | 1984 |
Dependence on treatment time of melphalan resistance and DNA cross-linking in human melanoma cell lines.
Topics: Caffeine; Cell Line; Cell Survival; Chlorambucil; DNA, Neoplasm; Drug Resistance; Drug Synergism; Hot Temperature; Humans; Kinetics; Mechlorethamine; Melanoma; Melphalan; Methyl Methanesulfonate; Thymidine | 1984 |
Chemotherapeutic drugs as indirect oxygen radiosensitizer.
Topics: Animals; Cells, Cultured; Chlorambucil; Cricetinae; Cricetulus; In Vitro Techniques; Mechlorethamine; Oxygen; Partial Pressure; Radiation-Sensitizing Agents | 1983 |
Microbicidal activity of peripheral blood monocytes from patients with Hodgkin's disease for Toxoplasma gondii.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Chlorambucil; Hodgkin Disease; Humans; Mechlorethamine; Monocytes; Prednisone; Procarbazine; Toxoplasma; Vincristine | 1982 |
Effects of alkylating agents on the DNA replication of cultured Yoshida sarcoma cells.
Topics: Alkylating Agents; Animals; Carmustine; Cell Division; Cell Survival; Chlorambucil; Cyclophosphamide; DNA Replication; Doxorubicin; Kinetics; Mechlorethamine; Melphalan; Mice; Sarcoma, Yoshida; Structure-Activity Relationship | 1982 |
Therapy for the child with nephrotic syndrome.
Topics: Adrenal Cortex Hormones; Child; Chlorambucil; Cyclophosphamide; Humans; Mechlorethamine; Nephrotic Syndrome | 1982 |
Radiation sensitivity modification by chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Carmustine; Chlorambucil; Cricetinae; Cricetulus; Fibroblasts; Mechlorethamine; Radiation-Sensitizing Agents; Time Factors | 1981 |
Sézary syndrome-an unusual case.
Topics: Administration, Topical; Chlorambucil; Female; Humans; Leukocyte Count; Mechlorethamine; Prednisone; Sezary Syndrome; Skin | 1981 |
[Evaluation of early treatment results in Hodgkin's disease during the cytostatic protocol containing methotrexate].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Epirubicin; Female; Hodgkin Disease; Humans; Lomustine; Male; Mechlorethamine; Methotrexate; Middle Aged; Prednisone; Procarbazine; Treatment Outcome; Vincristine | 1995 |
Predicting neutropenia after chemotherapy for lymphoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Leukocyte Count; Lymphoma; Male; Mechlorethamine; Middle Aged; Neutropenia; Predictive Value of Tests; Prednisolone; Procarbazine; Retrospective Studies; Risk Factors; Thrombocytopenia; Vinblastine; Vincristine | 1993 |
Molecular dynamics simulations of chlorambucil/DNA adducts. A structural basis for the 5'-GNC interstrand DNA crosslink formed by nitrogen mustards.
Topics: Alkylation; Base Sequence; Chlorambucil; Computer Simulation; Cross-Linking Reagents; DNA; DNA Adducts; Mechlorethamine; Models, Chemical; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation | 1995 |
Second malignant neoplasms in patients with Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy; Female; Hodgkin Disease; Humans; Incidence; Male; Mechlorethamine; Middle Aged; Neoplasms, Second Primary; New Zealand; Prednisone; Procarbazine; Radiotherapy Dosage; Risk Factors; Time Factors; Vinblastine; Vincristine | 1994 |
Retrovirus-mediated gene transfer of rat glutathione S-transferase Yc confers alkylating drug resistance in NIH 3T3 mouse fibroblasts.
Topics: 3T3 Cells; Animals; Blotting, Southern; Chlorambucil; Drug Resistance; Genetic Vectors; Glutathione Peroxidase; Glutathione Transferase; Mechlorethamine; Mice; Rats; Retroviridae; Transcription, Genetic; Transfection | 1994 |
Expression of a rat glutathione-S-transferase complementary DNA in rat mammary carcinoma cells: impact upon alkylator-induced toxicity.
Topics: Alkylating Agents; Animals; Biological Transport; Cell Line; Cell Nucleus; Chlorambucil; Cisplatin; DNA, Complementary; Gene Expression; Genetic Vectors; Glutathione Transferase; Macromolecular Substances; Mammary Neoplasms, Experimental; Mechlorethamine; Melphalan; Rats; RNA, Messenger; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1993 |
Lupus in the 1980s: III. Influence of clinical variables, biopsy, and treatment on the outcome in 150 patients with lupus nephritis seen at a single center.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Biopsy; Blood Component Removal; Chlorambucil; Cyclophosphamide; Disease-Free Survival; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Lupus Nephritis; Male; Mechlorethamine; Retrospective Studies; Steroids; Survival Rate; Treatment Outcome | 1995 |
Dose-response relationships of cytotoxicity, PFC response and histology in the spleen in rats treated with alkylating agents.
Topics: Animals; Antineoplastic Agents, Alkylating; Body Weight; Cell Count; Cell Survival; Chlorambucil; Cyclophosphamide; Dose-Response Relationship, Drug; Hemolytic Plaque Technique; Immune System; Injections, Intravenous; Male; Mechlorethamine; Melphalan; Organ Size; Rats; Rats, Inbred F344; Sensitivity and Specificity; Spleen | 1996 |
Excision of DNA adducts of nitrogen mustards by bacterial and mammalian 3-methyladenine-DNA glycosylases.
Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; Chlorambucil; DNA Adducts; DNA Glycosylases; Escherichia coli; Guanine; Humans; Mechlorethamine; Melphalan; Molecular Sequence Data; N-Glycosyl Hydrolases; Rats | 1996 |
The 5'-GNC preference for mustard cross-linking is preserved in a restriction fragment.
Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; Chlorambucil; Cross-Linking Reagents; Deoxyribonuclease EcoRI; DNA; DNA Damage; Mechlorethamine; Melphalan; Molecular Sequence Data; Nitrogen Mustard Compounds; Oligodeoxyribonucleotides; Structure-Activity Relationship; Substrate Specificity; Xenopus | 1996 |
Retrovirus-mediated gene transfer of rat glutathione S-transferase Yc confers in vitro resistance to alkylating agents in human leukemia cells and in clonogenic mouse hematopoietic progenitor cells.
Topics: Alkylating Agents; Animals; Blotting, Southern; Blotting, Western; Bone Marrow Transplantation; Chlorambucil; Clone Cells; Drug Resistance, Neoplasm; Female; Gene Transfer Techniques; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Hematopoietic Stem Cells; Humans; Leukemia; Mechlorethamine; Mice; Mice, Inbred C3H; Rats; Retroviridae; Transcription, Genetic; Transduction, Genetic; Tumor Cells, Cultured | 1996 |
Second malignancy in patients with Hodgkin's disease treated at the Royal Marsden Hospital.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chlorambucil; Female; Hodgkin Disease; Humans; Male; Mechlorethamine; Middle Aged; Neoplasms, Second Primary; Prednisone; Procarbazine; Risk; Risk Factors; Vinblastine; Vincristine | 1997 |
Protein-DNA interactions in the human beta-globin locus control region hypersensitive site-2 as revealed by four nitrogen mustards.
Topics: Aminacrine; Amsacrine; Cell Line; Chlorambucil; Chromatin; DNA Damage; DNA-Binding Proteins; Gene Expression Regulation; Globins; Humans; Mechlorethamine; Promoter Regions, Genetic | 1997 |
Effect of nucleosome structure on DNA interstrand cross-linking reactions.
Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; Chlorambucil; Cross-Linking Reagents; DNA, Ribosomal; Mechlorethamine; Melphalan; Molecular Sequence Data; Nitrogen Mustard Compounds; Nucleosomes; RNA, Ribosomal, 5S; Xenopus | 1998 |
Hodgkin's disease in children in southern Africa: epidemiological characteristics, morbidity and long-term outcome.
Topics: Adolescent; Age Distribution; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Child, Preschool; Chlorambucil; Dacarbazine; Doxorubicin; Female; Hodgkin Disease; Humans; Male; Mechlorethamine; Morbidity; Neoplasm Staging; Prednisolone; Prednisone; Procarbazine; Retrospective Studies; South Africa; Survival Rate; Treatment Outcome; Vinblastine; Vincristine | 1997 |
The effect of the Saccharomyces cerevisiae endo-exonuclease NUD1 gene expression on the resistance of HeLa cells to DNA-damaging agents.
Topics: Alkylating Agents; Cell Survival; Chlorambucil; Cisplatin; Deoxyribonucleases; DNA Damage; Gene Expression; Genes, Fungal; HeLa Cells; Humans; Mechlorethamine; Recombination, Genetic; RNA; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transfection; tRNA Methyltransferases; Ultraviolet Rays | 1999 |
High-dose BEAM chemotherapy with autologous haemopoietic stem cell transplantation for Hodgkin's disease is unlikely to be associated with a major increased risk of secondary MDS/AML.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Child; Child, Preschool; Chlorambucil; Cohort Studies; Combined Modality Therapy; Cytarabine; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Incidence; Infant; Leukemia, Myeloid; Life Tables; Lomustine; Male; Mechlorethamine; Melphalan; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Podophyllotoxin; Prednisolone; Prednisone; Procarbazine; Retrospective Studies; Risk; Salvage Therapy; Vinblastine; Vincristine | 1999 |
Molecular dynamics simulation of metallothionein-drug complexes.
Topics: Binding Sites; Chemical Phenomena; Chemistry, Physical; Chlorambucil; Computer Simulation; Crystallography, X-Ray; Cysteine; Mechlorethamine; Melphalan; Metallothionein; Models, Structural; Nitrogen Mustard Compounds; Protein Binding; Zinc | 2000 |
Mutations induced by some DNA minor groove binding alkylators in AS52 Chinese hamster cells.
Topics: Alkylating Agents; Animals; Bacterial Proteins; Benzimidazoles; Binding Sites; Bisbenzimidazole; Chlorambucil; CHO Cells; Cricetinae; DNA; Escherichia coli Proteins; Mechlorethamine; Micronucleus Tests; Mutation; Nitrogen Mustard Compounds; Pentosyltransferases; Point Mutation; Polymerase Chain Reaction; Proteins; Sequence Deletion; Structure-Activity Relationship; Thioguanine | 2000 |
Genetic damage by bifunctional agents in repair-active pre-meiotic stages of Drosophila males.
Topics: Animals; Antineoplastic Agents, Alkylating; Chlorambucil; DNA; DNA Adducts; DNA Damage; DNA Repair; Drosophila; Female; Larva; Male; Mechlorethamine; Meiosis; Mutagenesis; Mutagenicity Tests; Mutation; Spermatocytes; Time Factors | 2001 |
Covalent binding of nitrogen mustards to the cysteine-34 residue in human serum albumin.
Topics: Binding Sites; Chlorambucil; Cyclophosphamide; Cysteine; Drug Monitoring; Humans; In Vitro Techniques; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Protein Binding; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2002 |
Myelodysplastic syndrome and acute myeloid leukemia after autotransplantation for lymphoma: a multicenter case-control study.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Case-Control Studies; Child; Chlorambucil; Cohort Studies; Cyclophosphamide; Dose-Response Relationship, Radiation; Female; Humans; Leukemia, Myeloid; Leukemia, Radiation-Induced; Lymphoma; Male; Mechlorethamine; Middle Aged; Multivariate Analysis; Myelodysplastic Syndromes; Neoplasms, Second Primary; Peripheral Blood Stem Cell Transplantation; Prednisone; Procarbazine; Risk; Transplantation Conditioning; Transplantation, Autologous; Vincristine; Whole-Body Irradiation | 2003 |
Clinical trials of p-(di-2-chloroethylamino)-phenylbutyric acid (CB 1348) in malignant lymphoma.
Topics: Chlorambucil; Lymphoma; Mechlorethamine; Nitrogen Mustard Compounds; Phenylbutyrates | 1955 |
Evaluation of CB 1348 in Hodgkin's disease and allied disorders.
Topics: Arylsulfonates; Chlorambucil; Hodgkin Disease; Mechlorethamine; Nitrogen Mustard Compounds | 1956 |
Clinical experience with CB 1348 (NN-di(2-chloroethyl, -P-aminophenylbutyric acid) in the treatment of chronic lymphatic leukaemia.
Topics: Chlorambucil; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Mechlorethamine; Nitrogen Mustard Compounds | 1957 |
Therapeutic results in treatment of Hodgkin's disease with CB 1348 and R-48.
Topics: Chlorambucil; Hodgkin Disease; Mechlorethamine; Naphthalenes; Nitrogen Mustard Compounds | 1957 |
[Severe terminal purpura during CB 1348 therapy of chronic lymphoid leukemia].
Topics: Chlorambucil; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Mechlorethamine; Nitrogen Mustard Compounds; Purpura | 1957 |
Accidental ingestion of a toxic dose of chlorambucil; report of a case in a child.
Topics: Child; Chlorambucil; Drug-Related Side Effects and Adverse Reactions; Humans; Mechlorethamine; Nitrogen Mustard Compounds | 1957 |
[Clinical experiences with a new drug, chlorambucil (CB 1348), in malignant lymphogranuloma].
Topics: Chlorambucil; Hodgkin Disease; Mechlorethamine; Nitrogen Mustard Compounds | 1957 |
CHLORAMBUCIL.
Topics: Chlorambucil; Mechlorethamine; Nitrogen Mustard Compounds | 1958 |
Remissions induced by chlorambucil in chronic granulocytic leukemia.
Topics: Chlorambucil; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds | 1958 |
Treatment of malignant lymphoma with chlorambucil (CB 1348, leukeran).
Topics: Chlorambucil; Lymphoma; Mechlorethamine; Nitrogen Mustard Compounds | 1958 |
Hepatotoxicity due to chlorambucil; report of a case.
Topics: Chlorambucil; Drug Eruptions; Gastrointestinal Diseases; Humans; Liver; Mechlorethamine; Medical Records; Nitrogen Mustard Compounds | 1958 |
The action of chlorambucil (CB. 1348) and busulphan (myleran) on the haemopoietic organs of the rat.
Topics: Animals; Bone Marrow; Busulfan; Chlorambucil; Mechlorethamine; Nitrogen Mustard Compounds; Rats; Spleen | 1958 |
[Lymphoid leukemia treated by the combination of cortisone, CB 1348 & transfusions].
Topics: Blood Transfusion; Chlorambucil; Cortisone; Leukemia; Leukemia, Lymphoid; Mechlorethamine; Nitrogen Mustard Compounds | 1958 |
Clinical evaluation of CB 1348 in malignant lymphoma and related diseases.
Topics: Chlorambucil; Lymphoma; Mechlorethamine; Nitrogen Mustard Compounds | 1958 |
Clinical evaluation of CB 1348 in leukemias and lymphomas.
Topics: Chlorambucil; Leukemia; Lymphoma; Mechlorethamine; Nitrogen Mustard Compounds | 1958 |
Chlorambucil and triethylene thiophosphoramide in the treatment of neoplastic disease.
Topics: Antineoplastic Agents; Chlorambucil; Humans; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds; Thiotepa | 1958 |
P-(Di-2-chloroethyl) aminophenylbutyric acid (CB 1348) in the treatment of cancer.
Topics: Chlorambucil; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds | 1958 |
Summary of results obtained with CB 1348.
Topics: Chlorambucil; Mechlorethamine; Nitrogen Mustard Compounds | 1958 |
[Profuse lymphodermia; cure by combined cortisone & chloraminophen].
Topics: Chlorambucil; Cortisone; Disease; Lymph Nodes; Lymphatic Diseases; Mechlorethamine; Nitrogen Mustard Compounds; Skin Diseases | 1959 |
The effect of chlorambucil (CB 1348) on growth and metabolism.
Topics: Chlorambucil; Mechlorethamine; Nitrogen Mustard Compounds; Yeasts | 1958 |
[Observations on the application of CB-1348 in lymphatic leukemias].
Topics: Chlorambucil; Humans; Leukemia; Leukemia, Lymphoid; Mechlorethamine; Nitrogen Mustard Compounds | 1959 |
[Behavior of blood coagulation in the course of antimitotic treatment with CB-1348].
Topics: Antimitotic Agents; Blood Coagulation; Chlorambucil; Humans; Mechlorethamine; Nitrogen Mustard Compounds | 1959 |
[Observations & results in patients with malignant hemolymphatic diseases treated with p-(N,N-di-2-chloroethyl) aminophenylbutyric acid (CB 1348)].
Topics: Chlorambucil; Lymphoma; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds | 1959 |
Continuous chlorambucil therapy in primary macroglobulinemia of Waldenstrom: report of four cases.
Topics: Chlorambucil; Globulins; Mechlorethamine; Nitrogen Mustard Compounds; Serum Globulins; Waldenstrom Macroglobulinemia | 1961 |
The use of chlorambucil and steroids in the treatment of chronic lymphocytic leukaemia.
Topics: Adrenal Cortex Hormones; Chlorambucil; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Lymphocytes; Mechlorethamine; Nitrogen Mustard Compounds; Steroids | 1961 |
[p-(N, N-Di-2-chloroethyl)-aminophenylbutyric acid (CB-1348) in oncological therapy].
Topics: Chlorambucil; Internal Medicine; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds | 1960 |
[The effects of cytostatics on tooth development in albino rats. Part IV. Morphological changes of the incisors of the adult rat after puri-nethol, A-139, sanamycin, thio-TEPA, mitomen and leukeran].
Topics: Animals; Antineoplastic Agents; Chlorambucil; Cytostatic Agents; Incisor; Mechlorethamine; Mercaptopurine; Odontogenesis; Rats; Thiotepa; Tooth | 1959 |
[On the antitumor activity of chlorambucil in experimental conditions].
Topics: Chlorambucil; Mechlorethamine; Nitrogen Mustard Compounds | 1961 |
[Treatment of erythroderma with leukeran].
Topics: Chlorambucil; Dermatitis, Exfoliative; Mechlorethamine; Nitrogen Mustard Compounds | 1960 |
[Results of therapy with chlorambucil (N,N-bis-(2-chloroethyl)-p-aminophenylbutyric acid) in lymphatic systemic diseases, reticuloses and related diseases].
Topics: Chlorambucil; Disease; Humans; Lymphatic Diseases; Lymphatic System; Lymphatic Vessels; Mechlorethamine; Mononuclear Phagocyte System; Nitrogen Mustard Compounds; Peptide Nucleic Acids | 1961 |
The action of x-rays and chlorambucil on the cytoplasmic solid concentration of lymphocytes.
Topics: Chlorambucil; Cytoplasm; Lymphocytes; Mechlorethamine; Nitrogen Mustard Compounds; X-Rays | 1960 |
Experimental regional administration (perfusion and infusion) of chlorambucil (p-N,N-di-(beta-chloroethyl) aminophenylbutyric acid.
Topics: Chlorambucil; Infusions, Parenteral; Mechlorethamine; Nitrogen Mustard Compounds; Perfusion | 1961 |
[Restoration of hematopoiesis following a lethal dose of dimethyl myleran by isologic bone marrow transplantation in mice. Experiments on modification of intolerance to homologous bone marrow by 6-mercaptopurine, aminochlorambucil and cortisone].
Topics: Animals; Bone Marrow; Bone Marrow Transplantation; Busulfan; Chlorambucil; Cortisone; Hematopoiesis; Hematopoietic System; Mechlorethamine; Mercaptopurine; Mice; Nitrogen Mustard Compounds | 1961 |
The influence of Leukeran on the regeneration of rat livers following partial hepatectomy.
Topics: Animals; Chlorambucil; Hepatectomy; Liver; Mechlorethamine; Nitrogen Mustard Compounds; Rats; Regeneration | 1961 |
Evaluation of the effectiveness of radioactive phosphorus and chlorambucil in patients with chronic lymphocytic leukemia.
Topics: Chlorambucil; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Lymphocytes; Mechlorethamine; Nitrogen Mustard Compounds; Phosphorus; Phosphorus Radioisotopes | 1962 |
Effect of oxygen tension on the sensitivity of normal and tumor tissues to alkylating agents.
Topics: Alkylating Agents; Animals; Busulfan; Chlorambucil; Mechlorethamine; Oxygen; Sarcoma 180; Thiotepa; Triethylenemelamine | 1963 |
The chemotherapy of intrathoracic tumors.
Topics: Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Humans; Mechlorethamine; Methotrexate; Neoplasms; Prednisone; Progesterone; Testosterone; Thiotepa; Thoracic Neoplasms; Vinblastine | 1962 |
The effect of nitrogen mustard and maintenance chlorambucil in the treatment of advanced Hodgkin's disease.
Topics: Chlorambucil; Hodgkin Disease; Humans; Mechlorethamine | 1963 |
Treatment of macroglobulinaemia.
Topics: Chlorambucil; Humans; Mechlorethamine; Waldenstrom Macroglobulinemia | 1963 |
THE MALIGNANT LYMPHOMAS.
Topics: Adrenal Cortex Hormones; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasms; Radiotherapy Dosage; Sarcoma; Triethylenemelamine; Vinblastine | 1963 |
THE URIC ACID ANURIA OF LEUKEMIA TREATED BY DIALYSIS.
Topics: Adolescent; Anuria; Chlorambucil; Fluid Therapy; Humans; Kidney; Kidneys, Artificial; Leukemia; Mechlorethamine; Renal Dialysis; Uric Acid | 1963 |
LEUKEMIA. AN ANALYSIS OF 209 CASES FROM THE ELLIS FISCHEL STATE CANCER HOSPITAL.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Busulfan; Cancer Care Facilities; Child; Chlorambucil; Cobalt Isotopes; Leukemia; Leukemia, Lymphoid; Mechlorethamine; Methotrexate; Neoplasms | 1963 |
CHRONIC LYMPHATIC LEUKAEMIA AND ITS MANAGEMENT.
Topics: Adrenal Cortex Hormones; Chlorambucil; Geriatrics; Humans; Leukemia; Leukemia, Lymphoid; Mechlorethamine; Mustard Compounds | 1963 |
ANTI-MESODERMAL ACTIVITY OF A NITROGEN MUSTARD DERIVATIVE.
Topics: Animals; Chick Embryo; Chlorambucil; Congenital Abnormalities; Meat; Mechlorethamine; Mesoderm; Mice; Nitrogen Mustard Compounds; Poultry; Research; Toxicology | 1963 |
ROLE OF CHEMOTHERAPY IN THE MANAGEMENT OF EARLY HODGKIN'S DISEASE.
Topics: Bone Marrow Examination; Chlorambucil; Disease Management; Histological Techniques; Histology; Hodgkin Disease; Humans; Injections, Intravenous; Lymphography; Mechlorethamine; Neoplasms; Pathology | 1963 |
WEEKLY HIGH-DOSAGE GLUCOCORTICOSTEROID TREATMENT OF LYMPHOCYTIC LEUKEMIAS AND LYMPHOMAS.
Topics: Anemia; Anemia, Hemolytic; Betamethasone; Chlorambucil; Dexamethasone; Geriatrics; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Mercaptopurine; Methylprednisolone; Pharmacology; Prednisone; Radiotherapy; Thrombocytopenia; Triamcinolone | 1964 |
CURRENT STATUS OF CHEMOTHERAPY OF CANCER.
Topics: Alkylating Agents; Anti-Bacterial Agents; Antineoplastic Agents; Black People; Chemotherapy, Cancer, Regional Perfusion; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Dermatologic Agents; DNA; DNA, Neoplasm; Fluorouracil; Geriatrics; Humans; Mechlorethamine; Melphalan; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Pharmacology; Thiotepa; Toxicology; Triethylenemelamine; Vinblastine; Vincristine | 1964 |
PHAGOCYTOSIS IN RETICULUM CELL SARCOMA.
Topics: Adolescent; Black People; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Geriatrics; Leukemia; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Mercaptopurine; Neoplasms; Phagocytosis; Sarcoma; Steroids; Triethylenemelamine | 1964 |
CANCER CHEMOTHERAPY.
Topics: Adrenal Cortex Hormones; Aminopterin; Androgens; Antimetabolites; Antineoplastic Agents; Blood Platelet Disorders; Chemotherapy, Cancer, Regional Perfusion; Chlorambucil; Cyclophosphamide; Dactinomycin; Estrogens; Fluorouracil; Geriatrics; Humans; Leukopenia; Mechlorethamine; Mercaptopurine; Neoplasms; Nitrogen Mustard Compounds; Surgical Procedures, Operative; Thiotepa; Toxicology; Vinblastine | 1964 |
[HISTOPATHOLOGICAL EFFECTS OF ANTINEOPLASTIC AGENTS ON MALIGNANT LYMPHOMA].
Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Geriatrics; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Mitomycin; Neoplasms; Pathology; Pharmacology; Sarcoma | 1964 |
HODGKIN'S DISEASE OF THE LUNG WITH CAVITATION.
Topics: Antineoplastic Agents; Chlorambucil; Diagnosis, Differential; Hodgkin Disease; Lung Neoplasms; Mechlorethamine; Neoplasms; Pathology; Pneumonectomy; Thymoma; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
[THE NEPHROTIC SYNDROME OF "RHEUMATOID PURPURA"].
Topics: Abdomen; Abdomen, Acute; Abdominal Cavity; Child; Chlorambucil; Diagnosis; Glomerulonephritis; Hematuria; Humans; IgA Vasculitis; Mechlorethamine; Mercaptopurine; Nephrotic Syndrome; Nitrogen Mustard Compounds; Pathology; Potassium; Prednisone; Purpura | 1964 |
CHLORAMBUCIL-PREDNISOLONE THERAPY FOR DISSEMINATED BREAST CARCINOMA.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agents; Biomedical Research; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Humans; Mechlorethamine; Neoplasm Metastasis; Palliative Care; Prednisolone; Thiotepa; Toxicology | 1964 |
INFLUENCE OF SOME ANTITUMOR DRUGS ON BODY AND ORGANS GROWTH IN RATS.
Topics: Adrenal Glands; Antineoplastic Agents; Body Weight; Bone and Bones; Brain; Chlorambucil; Diaphragm; Esophagus; Gastrointestinal Tract; Growth; Heart; Humans; Kidney; Liver; Lung; Male; Mechlorethamine; Melphalan; Pharmacology; Prostate; Rats; Research; Spleen; Testis; Thiotepa; Thymus Gland; Urinary Bladder | 1964 |
LONG TERM RESULTS ACHIEVED WITH THE USE OF ALKYLATING AGENTS IN MALIGNANT LYMPHOMA AND HODGKIN'S DISEASE.
Topics: Alkylating Agents; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasms; Sarcoma | 1964 |
PNEUMOCYSTIS CARINII PNEUMONIA. CASE STUDIES WITH ELECTRON MICROSCOPY.
Topics: Chlorambucil; Chloramphenicol; Cytomegalovirus Infections; Diagnosis, Differential; Digoxin; Electrons; Hodgkin Disease; Humans; Hydrocortisone; Infant; Lung Diseases; Mechlorethamine; Microscopy; Microscopy, Electron; Neoplasms; Pathology; Penicillins; Plasma Cells; Pneumonia; Pneumonia, Pneumocystis; Streptomycin | 1964 |
NONSURGICAL TREATMENT OF PULMONARY CANCER.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Bronchogenic; Chlorambucil; Cytodiagnosis; Fluorouracil; Hodgkin Disease; Humans; Lung Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Mediastinal Neoplasms; Neoplasm Metastasis; Neoplasms; Palliative Care; Prednisone; Sarcoma; Vinblastine | 1964 |
THE MANAGEMENT OF LEUKEMIA AND LYMPHOMA.
Topics: Adrenal Cortex Hormones; Busulfan; Chlorambucil; Cortisone; Cyclophosphamide; Hodgkin Disease; Humans; Leukemia; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Mercaptopurine; Methotrexate; Neoplasms; Palliative Care; Sarcoma; Vinblastine | 1964 |
THE TREATMENT OF CANCER BY ISOLATION PERFUSION.
Topics: Alkylating Agents; Anti-Bacterial Agents; Antimetabolites; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Chlorambucil; Cyclophosphamide; Fluorouracil; Mechlorethamine; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Nursing; Thiotepa; Toxicology | 1964 |
EXPERIENCES WITH CHEMOTHERAPY IN GYNECOLOGIC CANCER.
Topics: Antineoplastic Agents; Biomedical Research; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Genital Neoplasms, Female; Humans; Hydroxyprogesterones; Mechlorethamine; Methotrexate; Neoplasms; Ovarian Neoplasms; Pregnancy; Sarcoma; Thiotepa; Toxicology; Trophoblastic Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Vincristine | 1964 |
REACTION OF BIOLIGICAL ALKYLATING AGENTS WITH REDUCED VITAMIN B12.
Topics: Alkylating Agents; Busulfan; Chlorambucil; Chromatography; Electrophoresis; Mannomustine; Mechlorethamine; Research; Vitamin B 12 | 1964 |
RADIATION AND DRUG INDUCED HYALINIZATION OF THE STOMACH.
Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Drug Therapy; Ganglioneuroma; Gastrointestinal Diseases; Hodgkin Disease; Leukemia; Leukemia, Myeloid; Liver Neoplasms; Lymphoma; Mechlorethamine; Mercaptopurine; Methotrexate; Neoplasms; Pathology; Radiation Injuries; Stomach; Toxicology; Vinblastine; Vincristine; Wilms Tumor | 1965 |
EXPECTANCY FOR LIFE IN CHRONIC LYMPHATIC LEUKEMIA.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Drug Therapy; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Mechlorethamine; Neoplasms; Phosphorus Isotopes | 1965 |
CYTOTOXIC ACTIVITY COMPARED WITH PHOTOMETRIC MEASUREMENTS OF SELECTED ALKYLATING AGENTS.
Topics: Alkylating Agents; Blood; Chemical Precipitation; Chlorambucil; Colorimetry; Cyclophosphamide; Injections; Injections, Intravenous; Mechlorethamine; Metabolism; Nitrogen Mustard Compounds; Pharmacology; Photometry; Rabbits; Research; Toxicology | 1965 |
Treatment of malignant lymphomas and lymphadenoses with leukeran.
Topics: Chlorambucil; Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Lymphoma; Mechlorethamine; Nitrogen Mustard Compounds | 1959 |
Chlorambucil in erythrodermia.
Topics: Chlorambucil; Dermatitis, Exfoliative; Humans; Mechlorethamine; Nitrogen Mustard Compounds; Skin Diseases | 1960 |
The clinical use of chlorambucil: a critical study.
Topics: Chlorambucil; Mechlorethamine; Nitrogen Mustard Compounds | 1959 |
[p-(Bis-2-chloroethylamino)-phenylbutyric acid (CB 1348) in oncological therapy].
Topics: Chlorambucil; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds; Phenylbutyrates | 1960 |
Effect of chlorambucil on synthesis of protein and nucleic acids in tumor-bearing mice.
Topics: Animals; Chlorambucil; Lymphoma, Non-Hodgkin; Mechlorethamine; Mice; Neoplasms; Nitrogen Mustard Compounds; Nucleic Acids; Proteins | 1960 |
CB 1348 therapy in leukemia and allied diseases.
Topics: Arylsulfonates; Chlorambucil; Leukemia; Mechlorethamine; Nitrogen Mustard Compounds | 1959 |
Modification of the structure of haemoglobin by chlorambucil.
Topics: Chlorambucil; Hemoglobins; Mechlorethamine; Nitrogen Mustard Compounds | 1962 |
Combination therapy with cobalt-60 and chlorambucil in the treatment of disseminated ovarian carcinomatosis.
Topics: Carcinoma; Chlorambucil; Cobalt; Cobalt Radioisotopes; Combined Modality Therapy; Female; Humans; Mechlorethamine; Nitrogen Mustard Compounds; Ovarian Neoplasms | 1962 |
[Results obtained with the use of chlorambucil in the treatment of malignant lymphopathies].
Topics: Chlorambucil; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Nitrogen Mustard Compounds; Sarcoma | 1961 |
Comparison of CB-1348 (chlorambucil, leukeran) and CB-1364.
Topics: Antineoplastic Agents; Chlorambucil; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mechlorethamine; Nitrogen Mustard Compounds | 1962 |
Cytokinetics and mechanism of action of AKO4: a novel nitrogen mustard targeted to bcr-abl.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Benzamides; Cell Proliferation; Chlorambucil; DNA Damage; Flow Cytometry; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; K562 Cells; Kinetics; Mechlorethamine; Megakaryocytes; Phosphorylation; Piperazines; Protein-Tyrosine Kinases; Pyrimidines | 2005 |
New mustard-linked 2-aryl-bis-benzimidazoles with anti-proliferative activity.
Topics: Amides; Base Pairing; Base Sequence; Benzaldehydes; Benzimidazoles; Cell Division; Cell Line, Tumor; Chlorambucil; Crystallography, X-Ray; DNA, Neoplasm; Esters; Humans; Mechlorethamine; Models, Molecular; Molecular Conformation; Oligodeoxyribonucleotides; Pyrrolidines; Rhodamines | 2006 |
Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences.
Topics: Adenosine Diphosphate Ribose; Antidotes; Antineoplastic Agents, Alkylating; Cell Line; Cell Proliferation; Cell Survival; Chemical Warfare Agents; Chlorambucil; DNA Adducts; Dose-Response Relationship, Drug; Drug Synergism; Genomic Instability; Humans; Keratinocytes; Mechlorethamine; Micronuclei, Chromosome-Defective; Mustard Gas; Nitrogen Mustard Compounds; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Signal Transduction; Time Factors | 2016 |
Comparison of the Lonidamine Potentiated Effect of Nitrogen Mustard Alkylating Agents on the Systemic Treatment of DB-1 Human Melanoma Xenografts in Mice.
Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Chlorambucil; Cyclophosphamide; Doxorubicin; Drug Synergism; Humans; Indazoles; Male; Mechlorethamine; Melanoma; Melphalan; Mice; Mice, Nude; Mice, SCID; Xenograft Model Antitumor Assays | 2016 |
Skin sensitizing effects of sulfur mustard and other alkylating agents in accordance to OECD guidelines.
Topics: Biomarkers; Chemical Warfare Agents; Chlorambucil; Guidelines as Topic; Humans; Irritants; Keratinocytes; Langerhans Cells; Mechlorethamine; Mustard Gas; Risk Assessment; Skin; Skin Irritancy Tests | 2019 |