mechlorethamine and caffeine

mechlorethamine has been researched along with caffeine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199012 (80.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.67)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Merriman, RL; Sladek, NE1
MacNaughton, AW; Winder, FG1
Schöneich, J; Wobus, AM1
Chang, JD; Fingert, HJ; Pardee, AB1
Sasaki, MS; Tonomura, A1
Aragrao, BR; Caldas, LR; Gomes, RA; Leitão, AC1
Gaudin, D; Yielding, KL1
Das, SK; Lau, CC; Pardee, AB1
Parsons, PG1
Lau, CC; Pardee, AB1
Byfield, JE; Chen, CT; Murnane, JP; Wang, CH1
Byfield, JE; Calabro-Jones, P; Murnane, JP; Ward, JF1
Cañedo, AD; Castilhos, B; Henriques, JA; Immich, BF; Lenz, G; Moura, DJ; Saffi, J1

Reviews

1 review(s) available for mechlorethamine and caffeine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

14 other study(ies) available for mechlorethamine and caffeine

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cytotoxic activity of mechlorethamine and melphalan against cultured tumor cells: potentiation by caffeine.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 206, Issue:2

    Topics: Animals; Antineoplastic Agents; Caffeine; Carcinoma 256, Walker; Cells, Cultured; Drug Synergism; Lymphoma; Mechlorethamine; Melphalan; Rats; Time Factors

1978
Increased DNA polymerase and ATP-dependent deoxyribonuclease activities following DNA damages in mycobacterium smegmatis.
    Molecular & general genetics : MGG, 1977, Feb-15, Volume: 150, Issue:3

    Topics: Acridines; Adenosine Triphosphate; Bacterial Proteins; Caffeine; Deoxyribonucleases; DNA-Directed DNA Polymerase; DNA, Bacterial; Ethidium; Ethyl Methanesulfonate; Fluorouracil; Mechlorethamine; Methyl Methanesulfonate; Mitomycins; Mutation; Mycobacterium; Nalidixic Acid; Proflavine; Ultraviolet Rays

1977
[A cytological test system for the routine determination of mutagenicity].
    Die Pharmazie, 1977, Volume: 32, Issue:3

    Topics: Ascitic Fluid; Caffeine; Cells, Cultured; Chromosome Aberrations; Cytarabine; Hydrazines; Isonicotinic Acids; Mechlorethamine; Methods; Mutation; Netropsin

1977
Cytotoxic, cell cycle, and chromosomal effects of methylxanthines in human tumor cells treated with alkylating agents.
    Cancer research, 1986, Volume: 46, Issue:5

    Topics: Alkylating Agents; Caffeine; Cell Cycle; Cell Line; Cell Survival; Chromosome Aberrations; Chromosomes; Drug Synergism; Humans; Interphase; Mechlorethamine; Pentoxifylline; Theobromine; Thiotepa; Urinary Bladder Neoplasms

1986
A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents.
    Cancer research, 1973, Volume: 33, Issue:8

    Topics: Alkanesulfonates; Alkylating Agents; Anemia, Aplastic; Antimetabolites; Caffeine; Cell Division; Cells, Cultured; Chloramphenicol; Chromosome Aberrations; Chromosomes; Cobalt Isotopes; Dactinomycin; DNA Repair; Humans; Lymphocytes; Mechlorethamine; Methoxsalen; Mitomycins; Nitrosoguanidines; Quinolines; Radiation Effects; Ultraviolet Rays

1973
Sensitization and repair in ultraviolet-irradiated bacteria.
    Anais da Academia Brasileira de Ciencias, 1973, Volume: 45 SUPPL

    Topics: Caffeine; Deoxyribodipyrimidine Photo-Lyase; DNA Repair; DNA Replication; DNA, Bacterial; Escherichia coli; Malondialdehyde; Mechlorethamine; Nitrosoguanidines; Photochemistry; Pyrimidines; Time Factors; Ultraviolet Rays

1973
Response of a "resistant" plasmacytoma to alkylating agents and x-ray in combination with the "excision" repair inhibitors caffeine and chloroquine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 131, Issue:4

    Topics: Animals; Caffeine; Chloroquine; Cricetinae; Cyclophosphamide; Depression, Chemical; DNA, Neoplasm; Mechlorethamine; Neoplasms, Experimental; Plasmacytoma

1969
Comparative analysis of caffeine and 3-aminobenzamide as DNA repair inhibitors in Syrian baby hamster kidney cells.
    Mutation research, 1984, Volume: 131, Issue:2

    Topics: Animals; Benzamides; Caffeine; Cell Line; Cell Nucleus; Cricetinae; Cycloheximide; DNA Repair; Drug Interactions; Flow Cytometry; Interphase; Kidney; Kinetics; Mechlorethamine; Mesocricetus; Methyl Methanesulfonate; Ultraviolet Rays

1984
Dependence on treatment time of melphalan resistance and DNA cross-linking in human melanoma cell lines.
    Cancer research, 1984, Volume: 44, Issue:7

    Topics: Caffeine; Cell Line; Cell Survival; Chlorambucil; DNA, Neoplasm; Drug Resistance; Drug Synergism; Hot Temperature; Humans; Kinetics; Mechlorethamine; Melanoma; Melphalan; Methyl Methanesulfonate; Thymidine

1984
Mechanism by which caffeine potentiates lethality of nitrogen mustard.
    Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:9

    Topics: Animals; Caffeine; Cell Cycle; Cell Survival; Cells, Cultured; Cricetinae; DNA Repair; Drug Synergism; Kidney; Mechlorethamine; Mitosis

1982
The structure of methylated xanthines in relation to their effects on DNA synthesis and cell lethality in nitrogen mustard-treated cells.
    Biophysical journal, 1981, Volume: 35, Issue:3

    Topics: Adenocarcinoma; Caffeine; Cell Line; Cell Survival; DNA Replication; Humans; Mechlorethamine; Structure-Activity Relationship; Xanthines

1981
Effects of methylated xanthines on mammalian cells treated with bifunctional alkylating agents.
    Nature, 1980, May-29, Volume: 285, Issue:5763

    Topics: Animals; Caffeine; Cell Line; Cell Survival; DNA Repair; DNA Replication; Drug Interactions; Humans; Mechlorethamine; Mice; Molecular Weight; Replicon

1980
Kin3 protein, a NIMA-related kinase of Saccharomyces cerevisiae, is involved in DNA adduct damage response.
    Cell cycle (Georgetown, Tex.), 2010, Jun-01, Volume: 9, Issue:11

    Topics: Caffeine; Cell Division; Cisplatin; DNA Adducts; DNA Breaks, Double-Stranded; DNA Repair; Doxorubicin; G2 Phase; Intracellular Signaling Peptides and Proteins; Mechlorethamine; Mitosis; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction

2010