mecamylamine has been researched along with scopolamine hydrobromide in 221 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 63 (28.51) | 18.7374 |
| 1990's | 43 (19.46) | 18.2507 |
| 2000's | 56 (25.34) | 29.6817 |
| 2010's | 56 (25.34) | 24.3611 |
| 2020's | 3 (1.36) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gnodde, HP; Schuiling, GA | 1 |
| Figallo, EM; Wingard, LB | 1 |
| Feger, J; Hammond, C; Rouzaire-Dubois, B | 1 |
| Barthó, L; Szolcsányi, J | 1 |
| Mason, ST | 1 |
| Delashaw, JB; Dement, WC; Foutz, AS; Guilleminault, C | 1 |
| Dudar, JD; Hadházy, P; Szerb, JC | 1 |
| Ahtee, L | 1 |
| Grenhoff, J; Svensson, TH | 1 |
| Riekkinen, M; Riekkinen, P; Sirviö, J | 3 |
| Bättig, K; Berz, S; Welzl, H | 1 |
| Allen, Y; Arendt, T; Gray, JA; Hodges, H; Lantos, PL; Mitchell, SN; Sinden, J | 1 |
| Butcher, LL; Levin, ED; McGurk, SR | 3 |
| Levin, ED; Rose, JE | 1 |
| Koivisto, E; Riekkinen, P; Sirviö, J | 1 |
| Butcher, LL; Levin, ED; McGurk, SR; Rose, JE | 1 |
| Aaltonen, M; Riekkinen, P; Sirviö, J | 1 |
| Ganguly, DK; Mitra, N; Mohanakumar, KP | 1 |
| Araki, Y; Furuno, K; Gomita, Y; Suemaru, K | 1 |
| Bouhassira, D; Deschênes, M; Hu, B; Steriade, M | 1 |
| Butcher, LL; Levin, ED; McGurk, SR; South, D | 1 |
| Mayer, DJ; Watkins, LR | 1 |
| Aston-Jones, G; Ennis, M | 1 |
| Daw, NW; Kratz, KE; Parkinson, D | 1 |
| Alaranta, S; Klinge, E; Sjöstrand, NO | 1 |
| Dixon, CE; Hamm, RJ; Hayes, RL; Jenkins, LW; Lyeth, BG; Stonnington, HH; Young, HF | 1 |
| Cheney, PD; Kasser, RJ | 1 |
| Alvarado-Garcia, R; Lee, MA; Witkin, JM; Witkin, KM | 1 |
| Forster, MJ; Lal, H; Retz, KC; Trimmer, CK | 1 |
| Furukawa, T; Imaizumi, J; Mizuki, Y; Noda, Y; Ushijima, I; Yamada, K; Yamada, M | 1 |
| Kile, JP; Turner, BB | 1 |
| Haefely, W | 2 |
| Flacke, W; Fleisch, JH; Gillis, RA | 1 |
| Ulrich, K | 1 |
| Akubue, PI | 1 |
| Gokhale, SD; Gulati, OD; Panchal, DI | 1 |
| Flacke, W; Gillis, RA | 1 |
| Goodyear, JM; Morrison, CF; Sellers, CM | 1 |
| Gogi, K; Hirayama, H; Ikeda, M; Urakawa, N | 1 |
| Watson, PJ | 1 |
| Glick, SD; Greenstein, S | 2 |
| Takikita, A | 1 |
| Bartolini, A; Bartolini, R; Domino, EF | 1 |
| Avis, HH; Pert, A | 1 |
| Grossman, SP; Ross, JF | 1 |
| Vaillant, GE | 1 |
| Glick, SD; Jarvik, ME; Nakamura, RK | 1 |
| Bartolini, A; Domino, EF | 1 |
| Newman, LM | 1 |
| Goldberg, ME; Hefner, M; Robichaud, RC; Sledge, K | 1 |
| Chiappetta, L; Jarvik, ME | 1 |
| Domino, EF; Olds, ME | 2 |
| Domino, EF; Morrison, J; Stitzer, M | 1 |
| Dutta, SN; Pradhan, SN | 1 |
| Holsti, LR; Mattila, MJ; Takki, S; Venho, VM | 1 |
| McCance, I; Phillis, JW | 1 |
| Krip, G; Pinsky, C; Vazquez, AJ | 1 |
| Botting, JH; Turmer, AD | 1 |
| Bartolini, A; Pepeu, G | 1 |
| Dilts, SL | 1 |
| Czuczwar, SJ; Kleinrok, Z; Sieklucka-Dziuba, M; Turski, L; Turski, WA | 1 |
| Calabrese, LC; Nicklaus, KJ; Weldon, DA | 1 |
| Hayes, RL; Katayama, Y; Kinscheck, IB; Mayer, DJ; Watkins, LR | 1 |
| Glick, SD; Guido, RA | 1 |
| Barnes, JC; Higgins, GA; Jones, DN; Kirkby, DL | 1 |
| Auman, JT; Briggs, SJ; Christopher, NC; Levin, ED | 1 |
| Arezo, S; James, JR; Johnson, JH; Rosecrans, JA; Villanueva, HF | 1 |
| Fernández, AG; Gristwood, RW; O'Neill, MF; Palacios, JM | 1 |
| Hasegawa, T; Itoh, A; Katono, Y; Nabeshima, T; Nitta, A | 1 |
| Bymaster, FP; Heath, I; Hendrix, JC; Shannon, HE | 1 |
| Changeux, JP; Vidal, C | 1 |
| Clow, K; Rasmusson, DD; Szerb, JC | 1 |
| Arankowsky-Sandoval, G; Gold, PE; Ragozzino, ME | 1 |
| Angelucci, L; Cozzolino, R; Ghirardi, O; Giuliani, A; Guaraldi, D; Ramacci, MT | 1 |
| Lewandowski, MH; Müller, CM; Singer, W | 1 |
| Moran, PM | 1 |
| Mazurkiewicz, M; Riekkinen, PJ; Sirviö, J | 1 |
| Jurklies, B; Kaelin-Lang, A; Niemeyer, G | 1 |
| Levin, ED; Torry, D | 1 |
| Lewandowski, MH | 1 |
| Kim, JS; Levin, ED | 1 |
| Katner, SN; Li, TK; Lumeng, L; McBride, WJ; Murphy, JM | 1 |
| Chambers, RA; Levin, ED; McEvoy, JP; Moore, J | 1 |
| MacDonald, E; Miettinen, R; Puumala, T; Riekkinen, P; Ruotsalainen, S; Sirviö, J | 1 |
| Hinchliffe, RM; Woodruff-Pak, DS | 1 |
| Greenshaw, AJ; Ivanová, S | 1 |
| Melchers, BP; Olivier, B; Philippens, IH | 1 |
| MacDonald, E; Miettinen, R; Riekkinen, M; Ruotsalainen, S; Sirviö, J | 1 |
| Hiramatsu, M; Kameyama, T; Murasawa, H; Nabeshima, T | 1 |
| Chen, Y; Constantini, S; Shohami, E; Weinstock, M | 1 |
| Johnson, DN; Little, JT; Minichiello, M; Sunderland, T; Weingartner, H | 1 |
| Dannals, RF; Finley, PA; Mochizuki, T; Musachio, JL; Scheffel, U; Wagner, HN; Zhan, Y | 1 |
| Harr, A; Ilivitsky, V; Knott, VJ; Mahoney, C | 1 |
| Boardman, A; Kaplan, S; Levin, ED | 1 |
| Hebeiss, K; Kilbinger, H | 1 |
| Kaneko, T; Kikusui, T; Tonohiro, T | 1 |
| Mirza, NR; Stolerman, IP | 1 |
| Hahn, B; Mirza, NR; Shoaib, M; Stolerman, IP | 1 |
| Bartolini, A; Bellucci, C; Dei, S; Galeotti, N; Ghelardini, C; Gualtieri, F; Manetti, D; Romanelli, MN; Scapecchi, S; Teodori, E | 1 |
| Maeda, M; Nakai, M | 1 |
| Jones, CK; Shannon, HE | 1 |
| Blaha, CD; Forster, GL | 1 |
| Kitajima, M; Matsumoto, K; Mohamed, AF; Tabata, K; Takayama, H; Watanabe, H | 1 |
| Czambel, RK; O'Toole, SM; Rhodes, ME; Rubin, RT; Wright, SL | 1 |
| Hsieh, CC; Hsieh, MT; Lin, LW; Tsai, CH; Wu, CR | 1 |
| Holsboer, F; Steckler, T | 1 |
| Członkowska, AI; Maciejak, P; Płaźnik, A; Siemiatkowski, M; Sienkiewicz-Jarosz, H; Szyndler, J | 1 |
| Armengaud, C; Gauthier, M; Lozano, VC | 1 |
| Addy, N; Christopher, NC; Levin, ED; Nakajima, A; Seidler, FJ; Slotkin, TA | 1 |
| Harada, N; Kakiuchi, T; Nishiyama, S; Ohba, H; Sato, K; Tsukada, H | 1 |
| Beaufort, C; Delerue, F; Durkin, TP; Leblond, L | 1 |
| Hsieh, MT; Kuo, LH; Tsai, FH; Wang, WH; Wu, CR | 1 |
| Ichitani, Y; Iwasaki, T; Kawai, H; Yamada, K | 1 |
| Bontempi, B; Lloyd, GK; Menzaghi, F; Risbrough, VB; Whelan, KT | 1 |
| Daniel, JM; Moerschbaecher, JM; Winsauer, PJ | 1 |
| Durkin, TP; Maviel, T | 1 |
| ESPELIEN, AD; EXLEY, KA; FLEMING, MC | 1 |
| BROWNLEE, G; JOHNSON, ES | 1 |
| BIRMINGHAM, AT; WILSON, AB | 1 |
| BURN, JH; NG, KK | 1 |
| Harding, JW; Olson, EA; Olson, ML; Qualls, JH; Stratton, JJ; Wright, JW | 1 |
| Goadsby, PJ; Kowacs, F; Williamson, DJ | 1 |
| Kelley, AE; Pratt, WE | 1 |
| Bartholomeusz, CF; Ellis, JR; Ellis, KA; Erskine, FF; Harrison, BJ; Nathan, PJ; Vitetta, L; Wesnes, KA | 1 |
| Bartholomeusz, CF; Croft, RJ; Ellis, J; Ellis, KA; Green, A; Ilic, S; Nathan, PJ; Phan, KL | 1 |
| Eidi, A; Eidi, M; Mahmoodi, G; Oryan, S | 1 |
| Chen, J; Kawamura, T; Nakahara, D; Nakamura, M; Takahashi, T | 1 |
| Miki, A; Morimoto, T; Okada, M; Otori, Y; Tano, Y | 1 |
| Hassel, B | 1 |
| McKelvey, J; Ranaldi, R; Sharf, R | 1 |
| Anggadiredja, K; Hiranita, T; Nawata, Y; Sakimura, K; Yamamoto, T | 1 |
| Born, J; Gais, S; Rasch, BH | 1 |
| Janssen, MC; Loos, M; Pattij, T; Schoffelmeer, AN; Smit, AB; van Gaalen, MM | 1 |
| Burk, JA; McQuail, JA | 1 |
| Fratta, W; Goldberg, SR; Scherma, M; Solinas, M; Tanda, G; Wertheim, CE | 1 |
| Tang, XC; Yan, H; Zhang, HY | 1 |
| Kamei, C; Masuoka, T; Mikami, A; Yamamoto, Y; Yasuda, M | 1 |
| Dumas, J; Hancur-Bucci, C; Naylor, M; Newhouse, P; Sites, C | 1 |
| Mair, RG; Newman, LA | 1 |
| Dumas, JA; Hynes, ML; McAllister, TW; McDonald, BC; Newhouse, PA; Saykin, AJ | 1 |
| Blaha, CD; Lester, DB; Miller, AD; Pate, TD | 1 |
| Buchanan, JT; Quinlan, KA | 1 |
| Bosch, D; Schmid, S | 1 |
| Dayan, P; Delicato, LS; Gieselmann, MA; Herrero, JL; Roberts, MJ; Thiele, A | 1 |
| Del Arco, A; Mora, F; Segovia, G | 1 |
| Dringenberg, HC; Habib, D | 1 |
| Kamei, C; Mikami, A; Shimada, K; Tarumi, T | 1 |
| Cauley, MC; Dawson, E; Kholdebarin, E; Levin, ED; Rezvani, AH | 1 |
| Belnik, AP; Ostrovskaya, RU; Radionova, KS | 1 |
| Born, J; Gais, S; Rasch, B | 1 |
| Harding, JW; Munn, C; Ross, RC; Wilson, WL; Wright, JW | 1 |
| Bussey, TJ; Dias, R; Saksida, LM; Talpos, JC; Winters, BD | 1 |
| Kang, JI; Vaucher, E | 1 |
| Dringenberg, HC; Gagolewicz, PJ | 1 |
| Kamei, C; Masuoka, T | 1 |
| Bohacek, J; Daniel, JM | 1 |
| Andersson, DR; Bergquist, F; Björnsson, E; Nissbrandt, H | 1 |
| Allison, C; Rushforth, SL; Shoaib, M; Wonnacott, S | 1 |
| Dumas, JA; Hynes, ML; McAllister, TW; McDonald, BC; Newhouse, PA; Saykin, AJ; West, JD | 1 |
| Terazima, E; Yoshino, M | 1 |
| Federley, M; Fjällström, AK; Persson, P; Stenqvist, P; Wadenberg, ML | 1 |
| Habel, U; Kircher, T; Reske, M; Thienel, R; Voss, B | 1 |
| Bushnell, PJ; Levin, ED; Rezvani, AH | 1 |
| Balthasar, N; Edwards, RH; Gittis, AH; Higley, MJ; Kreitzer, AC; Lowell, BB; Oldenburg, IA; Sabatini, BL; Seal, RP | 1 |
| Gacar, N; Gocmez, SS; Komsuoglu Celikyurt, I; Mutlu, O; Ulak, G; Utkan, T | 1 |
| Berke, JD; Fensterheim, BA; Gittis, AH; Kreitzer, AC; Leventhal, DK; Pettibone, JR | 1 |
| Hoseindoost, S; Nasehi, M; Zarrindast, MR | 1 |
| Barbosa, AK; Barros, DM; Campos, RC; Koth, AP; Parfitt, GM | 1 |
| Lai, M; Liu, H; Liu, Y; Ma, B; Sun, A; Zhang, F; Zhou, W; Zhou, X; Zhu, H | 1 |
| Kieffer, BL; Ouagazzal, AM; Prinssen, EP; Reiss, D; Wichmann, J | 1 |
| Biała, G; Budzyńska, B; Kruk-Słomka, M | 1 |
| Fletcher, ML; Gooch, A; Lee, E; Pavesi, E | 1 |
| Daphna, J; Joel, D; Roni, YY; Yankelevitch-Yahav, R | 1 |
| Addy, NA; Behrens, S; Mason, GF; Solecki, W; Wang, J; Wickham, RJ; Zwerling, B | 1 |
| Albert, K; Astur, R; Dumas, J; Johnson, J; Naylor, M; Newhouse, P | 1 |
| Boscaro, F; Cerbai, F; Di Russo, J; Giannetti, A; Giovannini, MG; Lana, D; Petkova-Kirova, P; Pugliese, AM | 1 |
| Braida, D; Gotti, C; Martucci, R; Ponzoni, L; Sala, M; Sparatore, F | 1 |
| Kosheleff, AR; Maidment, NT; Ostlund, SB | 1 |
| Ide, S; Kaneda, K; Kihara, Y; Minami, M; Shinohara, F | 1 |
| Carey, RM; Puche, A; Rothermel, M; Shipley, MT; Wachowiak, M | 1 |
| Braida, D; Martucci, R; Ponzoni, L; Sala, M | 1 |
| Buyukuysal, LR; Goktalay, G; Savci, V; Uslu, G | 1 |
| Gawel, K; Jenda, M; Kotlinska, JH; Labuz, K; Silberring, J | 1 |
| Biała, G; Budzyńska, B; Kruk-Słomka, M; Michalak, A | 1 |
| Katyal, A; Rai, S; Ray, RS | 1 |
| Hosking, JG; Lam, FC; Winstanley, CA | 1 |
| Malcolm, E; Shoaib, M; Silveira, MM; Winstanley, CA | 1 |
| Addy, NA; Nunes, EJ; Wickham, RJ | 2 |
| Addy, NA; Nunes, EJ; Solecki, WB; Wickham, RJ | 1 |
| Aminov, A; Bodnar, RJ; Dindyal, T; Kohen, I; Olsson, K; Pagirsky, J; Rotella, FM; Vig, V; Yenko, I | 1 |
| Ayala, YA; Malmierca, MS | 1 |
| Gold, PE; Newman, LA | 1 |
| Gawel, K; Gibula-Bruzda, E; Jenda, M; Kotlinska, JH; Labuz, K; Marszalek-Grabska, M; Silberring, J | 1 |
| Aitken, TJ; Collins, AL; Greenfield, VY; Ostlund, SB; Wassum, KM | 1 |
| Liu, AT; Maidment, NT; Ostlund, SB; Wassum, KM | 1 |
| Di Russo, J; Giovannini, MG; Lana, D; Mello, T; Wenk, GL | 1 |
| Abreu-Villaça, Y; Cauley, M; Hall, BJ; Junaid, S; Kiany, A; Levin, ED; White, H | 1 |
| Alvarez-Jimenez, R; Baakman, AC; den Burger, JCG; Goulooze, SC; Groeneveld, GJ; Klaassen, ES; Rissmann, R; Stevens, J; Swart, EL; van Gerven, JMA | 1 |
| Ahmed, T; Mahboob, A; Rashid, H | 1 |
| Blake, DT; Bunting, K; Carpenter-Hyland, EP; Griffeth, J; Terry, A; Vazdarjanova, A | 1 |
| Cui, R; Li, X; Ruan, H; Sun, J; Tian, L | 1 |
| Anderson, KG; Ozga, JE | 1 |
| Gieselmann, MA; Herrero, JL; Thiele, A | 1 |
| Bongianni, F; Cinelli, E; Iovino, L; Mutolo, D; Pantaleo, T | 1 |
| Blake, DT; Callahan, PM; Constantinidis, C; Crawford, J; Liu, R; Terry, AV | 1 |
| Forcelli, PA; Málková, L; Turchi, J; Waguespack, HF | 1 |
| Cai, Y; Dai, Z; Liang, L; Mao, Y; Pan, L; Qi, R; Su, Y; Wang, J | 1 |
| Addy, NA; Bitner, L; Hughley, SM; Nunes, EJ; Rupprecht, LE; Small, KM; Walton, SN | 1 |
| Aydin, S; Erol, K; Kaygisiz, B; Kilic, FS; Oner, S; Yildirim, E | 1 |
| Adermark, L; Ericson, M; Loftén, A; Söderpalm, B | 1 |
| Quigley, C; Treue, S; Veith, VK | 1 |
| Baxter, MG; Upright, NA | 1 |
3 review(s) available for mecamylamine and scopolamine hydrobromide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Multiple endogenous opiate and non-opiate analgesia systems: evidence of their existence and clinical implications.
Topics: Acupuncture Therapy; Analgesia; Animals; Cholecystokinin; Conditioning, Classical; Desipramine; Dimethyl Sulfoxide; Drug Interactions; Electroshock; Endorphins; Enkephalin, Leucine; Mecamylamine; Morphine; N-Methylscopolamine; Naloxone; Naltrexone; Norepinephrine; Proglumide; Rats; Receptors, Cell Surface; Receptors, Cholecystokinin; Scopolamine; Scopolamine Derivatives; Serotonin; Spinal Cord | 1986 |
Attention-modulating effects of cognitive enhancers.
Topics: Animals; Attention; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Humans; Mecamylamine; Nootropic Agents; Rats; Rats, Inbred SHR; Scopolamine | 2011 |
10 trial(s) available for mecamylamine and scopolamine hydrobromide
| Article | Year |
|---|---|
Combined nicotinic and muscarinic blockade in elderly normal volunteers: cognitive, behavioral, and physiologic responses.
Topics: Aged; Alzheimer Disease; Behavior; Blood Pressure; Brief Psychiatric Rating Scale; Cognition; Drug Synergism; Female; Heart Rate; Humans; Learning; Male; Mecamylamine; Memory; Middle Aged; Muscarinic Antagonists; Nicotinic Antagonists; Pupil; Reaction Time; Scopolamine | 1998 |
Muscarinic and nicotinic receptors synergistically modulate working memory and attention in humans.
Topics: Adult; Analysis of Variance; Attention; Double-Blind Method; Drug Interactions; Female; Flicker Fusion; Humans; Male; Mecamylamine; Memory, Short-Term; Muscarinic Antagonists; Neuropsychological Tests; Nicotinic Antagonists; Pain Measurement; Psychomotor Performance; Reaction Time; Receptors, Muscarinic; Receptors, Nicotinic; Recognition, Psychology; Scopolamine; Time Factors | 2006 |
Muscarinic and nicotinic receptor modulation of object and spatial n-back working memory in humans.
Topics: Adult; Analysis of Variance; Cognition; Double-Blind Method; Female; Humans; Male; Mecamylamine; Memory, Short-Term; Muscarinic Antagonists; Neuropsychological Tests; Nicotinic Antagonists; Placebos; Receptors, Muscarinic; Receptors, Nicotinic; Reproducibility of Results; Scopolamine | 2005 |
Combined blockade of cholinergic receptors shifts the brain from stimulus encoding to memory consolidation.
Topics: Adult; Blood Pressure; Brain; Cholinergic Antagonists; Cholinesterase Inhibitors; Drug Combinations; Emotions; Humans; Hydrocortisone; Male; Mecamylamine; Memory; Neuropsychological Tests; Physostigmine; Psychomotor Performance; Reaction Time; Receptors, Cholinergic; Scopolamine; Wakefulness | 2006 |
Estradiol interacts with the cholinergic system to affect verbal memory in postmenopausal women: evidence for the critical period hypothesis.
Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Cholinergic Antagonists; Cognition; Critical Period, Psychological; Cross-Over Studies; Double-Blind Method; Estradiol; Female; Humans; Mecamylamine; Memory Disorders; Mental Recall; Middle Aged; Postmenopause; Scopolamine; Verbal Learning | 2008 |
Impaired off-line consolidation of motor memories after combined blockade of cholinergic receptors during REM sleep-rich sleep.
Topics: Adult; Affect; Association Learning; Blood Pressure; Cardiovascular Physiological Phenomena; Cholinergic Antagonists; Double-Blind Method; Electroencephalography; Heart Rate; Humans; Male; Mecamylamine; Memory Disorders; Motor Skills; Neuropsychological Tests; Neurosecretory Systems; Reaction Time; Receptors, Cholinergic; Scopolamine; Sleep, REM; Young Adult | 2009 |
Cholinergic modulation of hippocampal activity during episodic memory encoding in postmenopausal women: a pilot study.
Topics: Aged; Brain; Brain Mapping; Double-Blind Method; Female; Humans; Magnetic Resonance Imaging; Mecamylamine; Memory; Middle Aged; Muscarinic Antagonists; Neuropsychological Tests; Nicotinic Antagonists; Pilot Projects; Postmenopause; Scopolamine | 2010 |
Cognitive performance and cholinergic transmission: influence of muscarinic and nicotinic receptor blockade.
Topics: Adult; Analysis of Variance; Cognition; Cross-Over Studies; Humans; Male; Mecamylamine; Muscarinic Antagonists; Neuropsychological Tests; Nicotinic Antagonists; Scopolamine; Single-Blind Method; Time Factors; Young Adult | 2010 |
Tamoxifen improves cholinergically modulated cognitive performance in postmenopausal women.
Topics: Aged; Attention; Cholinergic Antagonists; Cognition Disorders; Estrogen Antagonists; Female; Humans; Mecamylamine; Memory; Middle Aged; Neuropsychological Tests; Pain Measurement; Postmenopause; Psychiatric Status Rating Scales; Scopolamine; Tamoxifen; Time Factors; Verbal Learning | 2013 |
An anti-nicotinic cognitive challenge model using mecamylamine in comparison with the anti-muscarinic cognitive challenge using scopolamine.
Topics: Adult; Attention; Brain; Cognition; Cross-Over Studies; Double-Blind Method; Electroencephalography; Healthy Volunteers; Humans; Hypnotics and Sedatives; Learning; Male; Mecamylamine; Muscarinic Antagonists; Nicotine; Nicotinic Antagonists; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine; Time Factors; Young Adult | 2017 |
208 other study(ies) available for mecamylamine and scopolamine hydrobromide
| Article | Year |
|---|---|
Involvement of catecholaminergic and cholinergic mechanisms in the pulsatile release of LH in the long-term ovariectomized rat.
Topics: Animals; Apomorphine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Catecholamines; Circadian Rhythm; Female; Luteinizing Hormone; Mecamylamine; Methyltyrosines; Neurotransmitter Agents; Ovary; Phenoxybenzamine; Pituitary Gland; Pituitary Gland, Anterior; Pyrrolidinones; Rats; Scopolamine | 1976 |
Effects of physostigmine, scopolamine, and mecamylamine on the sleeping time induced by ketamine in the rat.
Topics: Animals; Drug Interactions; Ketamine; Male; Mecamylamine; Physostigmine; Rats; Scopolamine; Sleep; Time Factors | 1979 |
Pharmacological properties of acetylcholine-induced excitation of subthalamic nucleus neurones.
Topics: Acetylcholine; Animals; Atropine; Brain; Corpus Striatum; Electric Stimulation; In Vitro Techniques; Iontophoresis; Magnesium; Mecamylamine; Neurons; Physostigmine; Rats; Scopolamine; Thalamus | 1979 |
Capsaicin-sensitive innervation of the guinea-pig taenia caeci.
Topics: Animals; Capsaicin; Cecum; Electric Stimulation; Fatty Acids, Unsaturated; Female; Guanethidine; Guinea Pigs; In Vitro Techniques; Male; Mecamylamine; Muscle Contraction; Muscle, Smooth; Physostigmine; Scopolamine | 1979 |
Central noradrenergic--cholinergic interaction and locomotor behavior.
Topics: Acetylcholine; Animals; Arecoline; Catalepsy; Humans; Hydroxydopamines; Hypothalamus; Male; Mecamylamine; Mesencephalon; Motor Activity; Nicotine; Norepinephrine; Rats; Scopolamine | 1979 |
Cholinergic mechanisms and cataplexy in dogs.
Topics: Animals; Atropine; Cataplexy; Dogs; Female; Humans; Male; Mecamylamine; Neostigmine; Nicotine; Parasympatholytics; Parasympathomimetics; Physostigmine; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine | 1979 |
Release of [3H]acetylcholine from rat hippocampal slices: effect of septal lesion and of graded concentrations of muscarnic agonists and antagonists.
Topics: Acetylcholine; Animals; Arecoline; Atropine; Benzilates; Carbachol; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Mecamylamine; Oxotremorine; Pilocarpine; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine; Septum Pellucidum | 1977 |
Effect of cholingeric drugs on methadone-induced catalepsy and stereotypies in rats treated chronically with methadone.
Topics: Animals; Atropine; Behavior; Catalepsy; Drug Synergism; Hexamethonium Compounds; Humans; Male; Mecamylamine; Methadone; Nicotine; Parasympathomimetics; Pilocarpine; Rats; Scopolamine; Stereotyped Behavior | 1976 |
Nicotinic and muscarinic components of rat brain dopamine synthesis stimulation induced by physostigmine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Male; Mecamylamine; Muscarine; Nicotine; Physostigmine; Rats; Rats, Sprague-Dawley; Scopolamine | 1992 |
Effects of combined methysergide and mecamylamine/scopolamine treatment on spatial navigation.
Topics: Animals; Drug Combinations; Male; Mecamylamine; Methysergide; Motor Activity; Rats; Rats, Inbred Strains; Scopolamine; Space Perception | 1992 |
The effects of anticholinergic drugs on delayed time discrimination performance in rats.
Topics: Animals; Brain; Cholinergic Fibers; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Male; Mecamylamine; Mental Recall; Parasympatholytics; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine; Time Perception | 1992 |
The effects of cholinergic drugs and cholinergic-rich foetal neural transplants on alcohol-induced deficits in radial maze performance in rats.
Topics: Acetylcholine; Alcohol Drinking; Alcoholism; Animals; Brain Mapping; Brain Tissue Transplantation; Cholinergic Fibers; Discrimination Learning; Ethanol; Fetal Tissue Transplantation; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Mental Recall; Mesencephalon; N-Methylscopolamine; Nerve Regeneration; Nicotine; Norepinephrine; Orientation; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Retention, Psychology; Scopolamine; Scopolamine Derivatives | 1991 |
Impairment of radial-arm maze performance in rats following lesions involving the cholinergic medial pathway: reversal by arecoline and differential effects of muscarinic and nicotinic antagonists.
Topics: Animals; Arecoline; Caudate Nucleus; Cholinergic Fibers; Female; Learning; Mecamylamine; Memory; Nerve Regeneration; Putamen; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine | 1991 |
Nicotinic and muscarinic interactions and choice accuracy in the radial-arm maze.
Topics: Animals; Choice Behavior; Drug Interactions; Female; Learning; Mecamylamine; Memory; Nicotine; Pilocarpine; Rats; Rats, Inbred Strains; Reference Values; Scopolamine | 1991 |
Joint modulation of neocortical electrical activity by nicotinic and muscarinic receptors.
Topics: Animals; Cerebral Cortex; Drug Interactions; Electroencephalography; Male; Mecamylamine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine; Substantia Innominata | 1991 |
Characterization of the cognitive effects of combined muscarinic and nicotinic blockade.
Topics: Animals; Appetitive Behavior; Benzazepines; Brain; Discrimination Learning; Dopamine Agents; Dopamine Antagonists; Ergolines; Female; Mecamylamine; Memory; Mental Recall; Orientation; Quinpirole; Rats; Reaction Time; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine | 1990 |
Effects of concurrent manipulations of nicotinic and muscarinic receptors on spatial and passive avoidance learning.
Topics: Animals; Avoidance Learning; Dose-Response Relationship, Drug; Male; Mecamylamine; Memory; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine; Space Perception; Swimming | 1990 |
Tremorogenesis by physostigmine is unrelated to acetylcholinesterase inhibition: evidence for serotoninergic involvement.
Topics: Acetylcholinesterase; Animals; Atropine; Caudate Nucleus; Cyproheptadine; Mecamylamine; Mesencephalon; Methysergide; Mice; Mice, Inbred BALB C; Physostigmine; Putamen; Scopolamine; Serotonin; Tremor | 1990 |
Nicotine-induced tail-tremor and drug effects.
Topics: Animals; Arecoline; Atropine; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Nicotine; Physostigmine; Rats; Rats, Inbred Strains; Scopolamine; Tail; Tremor | 1989 |
Radial-arm maze performance in rats is impaired by a combination of nicotinic-cholinergic and D2 dopaminergic antagonist drugs.
Topics: Animals; Benzazepines; Dopamine Antagonists; Drug Interactions; Female; Ganglionic Stimulants; Haloperidol; Mecamylamine; Parasympathomimetics; Psychomotor Performance; Raclopride; Rats; Rats, Inbred Strains; Salicylamides; Scopolamine | 1989 |
Nicotinic-dopaminergic relationships and radial-arm maze performance in rats.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Haloperidol; Learning; Mecamylamine; Memory; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Dopamine; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine | 1989 |
The blockage of ponto-geniculo-occipital waves in the cat lateral geniculate nucleus by nicotinic antagonists.
Topics: Action Potentials; Animals; Cats; Electric Stimulation; Evoked Potentials; Geniculate Bodies; Hexamethonium; Hexamethonium Compounds; Mecamylamine; Occipital Lobe; Optic Chiasm; Pons; Reference Values; Scopolamine | 1988 |
Effects of combined muscarinic and nicotinic blockade on choice accuracy in the radial-arm maze.
Topics: Animals; Brain; Discrimination Learning; Female; Mecamylamine; Neurons; Orientation; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine | 1989 |
Activation of locus coeruleus from nucleus paragigantocellularis: a new excitatory amino acid pathway in brain.
Topics: Amino Acids; Animals; Dipeptides; Electric Stimulation; Evoked Potentials; Glutamates; Kynurenic Acid; Locus Coeruleus; Male; Mecamylamine; Medulla Oblongata; Neural Inhibition; Neural Pathways; Rats; Rats, Inbred Strains; Scopolamine | 1988 |
Evidence for a nicotinic component to the actions of acetylcholine in cat visual cortex.
Topics: Animals; Binding, Competitive; Cats; Evoked Potentials, Visual; Geniculate Bodies; Kinetics; Mecamylamine; Nicotine; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine; Subcellular Fractions; Visual Cortex | 1988 |
Pharmacological analysis of nicotinic relaxation of bovine retractor penis muscle.
Topics: Acetylcholine; Animals; Carbachol; Cattle; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Hexamethonium Compounds; Lidocaine; Male; Mecamylamine; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nicotine; Oxygen; Penis; Scopolamine; Tetrodotoxin | 1988 |
Effects of anticholinergic treatment on transient behavioral suppression and physiological responses following concussive brain injury to the rat.
Topics: Animals; Blood Pressure; Brain; Brain Concussion; Heart Rate; Male; Mecamylamine; N-Methylscopolamine; Parasympatholytics; Rats; Rats, Inbred Strains; Reflex; Scopolamine; Scopolamine Derivatives | 1988 |
DFP action on rat superior colliculus: localization and role of cholinergic receptors.
Topics: Animals; Atropine; Female; Isoflurophate; Male; Mecamylamine; Neural Pathways; Oxotremorine; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Retina; Scopolamine; Superior Colliculi | 1987 |
Nonmuscarinic neurotoxicity of oxotremorine.
Topics: Animals; Arecoline; Atropine; Atropine Derivatives; Benactyzine; Benztropine; Crying; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Male; Mecamylamine; Nervous System; Nicotine; Oxotremorine; Pilocarpine; Rats; Rats, Inbred Strains; Salivation; Scopolamine; Seizures; Time Factors | 1987 |
Motor responses of autoimmune NZB/B1NJ and C57BL/6Nnia mice to arecoline and nicotine.
Topics: Animals; Arecoline; Dose-Response Relationship, Drug; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Inbred NZB; Motor Activity; Nicotine; Receptors, Muscarinic; Scopolamine; Silicone Oils; Tremor | 1987 |
Characteristics of yawning behavior induced by apomorphine, physostigmine and pilocarpine.
Topics: Animals; Apomorphine; Behavior, Animal; Haloperidol; Male; Mecamylamine; N-Methylscopolamine; Physostigmine; Pilocarpine; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives; Time Factors | 1985 |
Serotonergic and cholinergic interaction in the regulation of pituitary-adrenal function in rats.
Topics: Animals; Cholinergic Fibers; Corticosterone; Male; Mecamylamine; Methysergide; Physostigmine; Pituitary-Adrenal System; Rats; Rats, Brattleboro; Rats, Inbred Strains; Scopolamine; Serotonin; Stress, Physiological | 1985 |
Muscarinic postsynaptic events in the cat superior cervical ganglion in situ.
Topics: Acetylcholine; Action Potentials; Animals; Cats; Electric Stimulation; Ganglia, Autonomic; Hexamethonium Compounds; Isoproterenol; Mecamylamine; Parasympathomimetics; Physostigmine; Pilocarpine; Scopolamine; Stimulation, Chemical; Tetraethylammonium Compounds | 1974 |
Nicotinic and muscarinic receptors in the cardiac sympathetic ganglia of the dog.
Topics: Acetylcholine; Animals; Atropine; Chlorisondamine; Dogs; Ganglia, Autonomic; Heart Rate; Hexamethonium Compounds; Mecamylamine; Scopolamine; Sensory Receptor Cells; Synaptic Transmission; Tubocurarine | 1969 |
The effects of l,l-dimethyl-4-phenyl-piperazinium (DMPP) in the cat superior cervical ganglion in situ.
Topics: Acetylcholine; Action Potentials; Angiotensin II; Animals; Atropine; Bradykinin; Cats; Cesium; Denervation; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Electrodes; Ganglia, Spinal; Ganglionic Stimulants; Hexamethonium Compounds; In Vitro Techniques; Isoproterenol; Mecamylamine; Mesylates; Ouabain; Piperazines; Quaternary Ammonium Compounds; Scopolamine; Serotonin; Tubocurarine | 1974 |
A direct and an indirect action of 5-hydroxytryptamine on the distal part of the isolated colon of the rat.
Topics: Acetylcholine; Animals; Cholinesterase Inhibitors; Cocaine; Colon; Hexamethonium Compounds; Histamine; Lysergic Acid Diethylamide; Male; Mecamylamine; Muscle Contraction; Muscle, Smooth; Nicotine; Piperazines; Procaine; Rats; Scopolamine; Serotonin | 1965 |
The site of action of drugs on the isolated taenia caeci from the guinea-pig.
Topics: Acetylcholine; Animals; Cecum; Cocaine; Female; Guinea Pigs; Hexamethonium Compounds; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Insecticides; Lysergic Acid Diethylamide; Male; Mecamylamine; Morphine; Muscle Contraction; Nicotine; Piperazines; Procaine; Scopolamine; Serotonin; Sympathomimetics | 1966 |
An analysis of the sympathomimetic effects of acetylcholine of the rat ileum.
Topics: Acetylcholine; Amphetamine; Animals; Bretylium Compounds; Choline; Cocaine; Dextroamphetamine; Drug Synergism; Epinephrine; Ethanolamines; Female; Guanethidine; Hexamethonium Compounds; Ileum; In Vitro Techniques; Male; Mecamylamine; Muscle Contraction; Muscle, Smooth; Nicotine; Pempidine; Phentolamine; Rats; Reserpine; Scopolamine; Xylenes | 1967 |
Dual transmission in the stellate ganglion of the dog.
Topics: Acetylcholine; Animals; Atropine; Chlorisondamine; Cordotomy; Depression, Chemical; Dogs; Ganglionic Blockers; Hexamethonium Compounds; Isoflurophate; Mecamylamine; Neostigmine; Nicotine; Parasympatholytics; Physostigmine; Scopolamine; Stellate Ganglion; Synaptic Transmission; Tetraethylammonium Compounds; Tubocurarine | 1968 |
Antagonism by antimuscarinic and ganglion-blocking drugs of some of the behavioural effects of nicotine.
Topics: Acetylcholine; Analysis of Variance; Animals; Atropine; Blood Pressure; Chlorisondamine; Conditioning, Operant; Ganglionic Blockers; Male; Mecamylamine; Nicotine; Parasympatholytics; Pupil; Rats; Scopolamine | 1969 |
A ganglion-blocking action of the toxin isolated from Japanese ivory shell (Babylonia japonica).
Topics: Animals; Carbachol; Cats; Ganglionic Blockers; Hexamethonium Compounds; Japan; Mecamylamine; Mollusca; Rabbits; Scopolamine; Toxins, Biological | 1970 |
The triphasic response of the isolated superior cervical ganglion of the rat to cholinergic stimulants.
Topics: Acetylcholine; Action Potentials; Animals; Carbachol; Dextroamphetamine; Dibenzylchlorethamine; Epinephrine; Ethanolamines; Ganglia, Spinal; Guanethidine; Hexamethonium Compounds; Isoproterenol; Mecamylamine; Nicotine; Norepinephrine; Parasympathomimetics; Phentolamine; Physostigmine; Pilocarpine; Piperazines; Rats; Scopolamine; Tetraethylammonium Compounds; Tubocurarine | 1972 |
Differential effects of scopolamine and mecamylamine on passive avoidance behavior.
Topics: Animals; Avoidance Learning; Behavior, Animal; Conditioning, Psychological; Depression, Chemical; Drug Interactions; Female; Injections, Intraperitoneal; Mecamylamine; Mice; Mice, Inbred Strains; Scopolamine | 1972 |
[Mechanism of catecholamine release in the excised guinea pig vas deferens, with special reference to the role of acetylcholine].
Topics: Acetylcholine; Animals; Atropine; Bretylium Compounds; Calcium; Catecholamines; Chlorpromazine; Electric Stimulation; Guinea Pigs; Hemicholinium 3; Hexamethonium Compounds; In Vitro Techniques; Male; Mecamylamine; Muscle Contraction; Norepinephrine; Pempidine; Phentolamine; Physostigmine; Reserpine; Scopolamine; Vas Deferens | 1972 |
Effects of physostigmine on brain acetylcholine content and release.
Topics: Acetylcholine; Animals; Brain; Brain Chemistry; Cats; Caudate Nucleus; Cerebral Cortex; Female; Hippocampus; Male; Mecamylamine; Pentobarbital; Physostigmine; Rats; Scopolamine; Time Factors | 1973 |
Pharmacological inhibition of eating, drinking and prandial drinking.
Topics: Animals; Appetite Regulation; Dextroamphetamine; Drinking Behavior; Drug Synergism; Eating; Feeding Behavior; Female; Hunger; Hypothalamus; Mecamylamine; Neural Inhibition; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Satiation; Scopolamine; Synapses; Thirst | 1973 |
A comparison of the effects of muscarinic and nicotinic anticholinergic drugs on habituation and fear conditioning in rats.
Topics: Animals; Conditioning, Operant; Drinking Behavior; Electroshock; Fear; Ganglionic Stimulants; Habituation, Psychophysiologic; Hexamethonium Compounds; Male; Mecamylamine; Parasympatholytics; Parasympathomimetics; Rats; Scopolamine; Time Factors; Water Deprivation | 1974 |
Intrahippocampal application of cholinergic agents and blockers: effects on rats in differential reinforcement of low rates and Sidman avoidance paradigms.
Topics: Animals; Atropine; Avoidance Learning; Behavior, Animal; Hippocampus; Inhibition, Psychological; Male; Mecamylamine; Methacholine Compounds; Nicotine; Parasympatholytics; Parasympathomimetics; Rats; Receptors, Cholinergic; Reinforcement Schedule; Scopolamine | 1974 |
A comparison of antagonists of physostigmine-induced suppression of behavior.
Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Chlorpromazine; Columbidae; Diphenhydramine; Haplorhini; Imipramine; Male; Mecamylamine; Muscles; Parasympatholytics; Physostigmine; Scopolamine; Trihexyphenidyl | 1967 |
Inhibition by drugs of smoking behaviour in monkeys.
Topics: Air; Animals; Behavior, Animal; Depression, Chemical; Dextroamphetamine; Discrimination, Psychological; Haplorhini; Hexamethonium Compounds; Mecamylamine; Pentobarbital; Scopolamine; Smoking | 1970 |
Studies on the paradoxical interaction of physostigmine and pentobarbital on regional brain acetylcholine content of various animal species.
Topics: Acetylcholine; Animals; Anura; Brain Chemistry; Cats; Cerebral Cortex; Drug Interactions; Male; Mecamylamine; Pentobarbital; Physostigmine; Rats; Rats, Inbred Strains; Scopolamine | 1972 |
Effects of cholinergic agonists and antagonists on self-stimulation behavior in the rat.
Topics: Animals; Atropine; Conditioning, Operant; Electric Stimulation; Electrodes, Implanted; Hypothalamus; Injections, Intraperitoneal; Male; Mecamylamine; Methamphetamine; Neostigmine; Nicotine; Parasympatholytics; Parasympathomimetics; Physostigmine; Pilocarpine; Rats; Receptors, Cholinergic; Scopolamine; Self Stimulation | 1972 |
Learning impairment after three classes of agents which modify cholinergic function.
Topics: Animals; Avoidance Learning; Cholinesterase Inhibitors; Conditioning, Psychological; Depression, Chemical; Drinking Behavior; Fear; Learning; Male; Mecamylamine; Mice; Motor Activity; Naphthalenes; Parasympatholytics; Pyridines; Rats; Scopolamine; Vinyl Compounds | 1971 |
Comparison of learning impairment and activity depression produced by two classes of cholinergic blocking agents.
Topics: Animals; Avoidance Learning; Bromides; Depression, Chemical; Female; Hexamethonium Compounds; Mecamylamine; Mice; Motor Activity; Parasympatholytics; Scopolamine | 1969 |
Differential effects of cholinergic agonists on self-stimulation and escape behavior.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Brain; Brain Chemistry; Electric Stimulation; Electrodes; Escape Reaction; Hypothalamus; Male; Mecamylamine; Mesencephalon; Neostigmine; Nicotine; Nicotinic Acids; Parasympathomimetics; Physostigmine; Rats; Scopolamine; Self Stimulation | 1969 |
Effects of nicotine on fixed-interval behavior and their modification by cholinergic antagonists.
Topics: Animals; Conditioning, Operant; Dextroamphetamine; Drug Tolerance; Hexamethonium Compounds; Male; Mecamylamine; Nicotine; Nicotinic Acids; Parasympatholytics; Rats; Reinforcement Schedule; Scopolamine | 1970 |
Behavioral effects of arecoline in rats.
Topics: Animals; Avoidance Learning; Conditioning, Operant; Depression, Chemical; Drug Antagonism; Electroshock; Escape Reaction; Male; Mecamylamine; Motor Activity; Nicotinic Acids; Rats; Reinforcement Schedule; Scopolamine | 1970 |
Absorption of drugs in vitro from the rat intestine damaged by triparanol or irradiation.
Topics: Aminopyrine; Analgesics; Animals; Aspirin; Depression, Chemical; Ethionamide; Female; Intestinal Absorption; Intestine, Small; Mecamylamine; Morphine; Phenobarbital; Radiation Effects; Radiation Injuries, Experimental; Rats; Scopolamine; Stimulation, Chemical; Triparanol | 1970 |
Cholinergic mechanisms in the cerebellar cortex.
Topics: Acetylcholine; Acetylcholinesterase; Alkaloids; Animals; Atropine; Carbachol; Cats; Cerebral Cortex; Choline; Electric Stimulation; Gallamine Triethiodide; Glutamates; Hexamethonium Compounds; Indoles; Mecamylamine; Methacholine Compounds; Neurons; Nicotine; Nicotinic Acids; Physostigmine; Purkinje Cells; Quaternary Ammonium Compounds; Scopolamine; Synapses; Tubocurarine | 1968 |
[vidence for a muscarinic inhibitory mechanism in the cerebral cortex].
Topics: Acetylcholine; Animals; Atropine; Cats; Cerebral Cortex; Drug Antagonism; Electric Stimulation; Electrophysiology; Female; Male; Mecamylamine; Nicotine; Nicotinic Acids; Parasympathomimetics; Physostigmine; Pilocarpine; Pyrrolidines; Scopolamine; Seizures; Tremorine | 1969 |
Comparison of muscarinic and nicotinic cholinergic agonists on self-stimulation behavior.
Topics: Animals; Hypothalamus; Male; Mecamylamine; Nicotine; Nicotinic Acids; Physostigmine; Quaternary Ammonium Compounds; Rats; Reinforcement, Psychology; Scopolamine; Self Stimulation; Sensory Receptor Cells | 1969 |
Mode of action of vasopressin on isolated proximal colon of the guinea-pig.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Cocaine; Cold Temperature; Colon; Guinea Pigs; Hexamethonium Compounds; Histamine; Hypoxia; In Vitro Techniques; Mecamylamine; Morphine; Muscle Contraction; Nicotine; Pentolinium Tartrate; Procaine; Scopolamine; Serotonin; Tetraethylammonium Compounds; Vasopressins | 1966 |
Investigations into the acetylcholine output from the cerebral cortex of the cat in the presence of hyoscine.
Topics: Acetylcholine; Anesthetics, Local; Animals; Cats; Cerebral Cortex; Female; Male; Mecamylamine; Physostigmine; Scopolamine | 1967 |
Berry CA: Effect of cholinergic drugs on passive avoidance in the mouse.
Topics: Animals; Ataxia; Atropine; Avoidance Learning; Galvanic Skin Response; Locomotion; Male; Mecamylamine; Memory; Mice; Neostigmine; Parasympathomimetics; Physostigmine; Quaternary Ammonium Compounds; Scopolamine | 1967 |
Studies on the mechanism of wet dog shakes produced by carbachol in rats.
Topics: Animals; Atropine; Behavior, Animal; Brain; Carbachol; Catecholamines; Dopamine; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Male; Mecamylamine; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Inbred Strains; Scopolamine; Serotonin | 1984 |
Rotational behavior following cholinergic stimulation of the superior colliculus in rats.
Topics: Acetylcholine; Animals; Behavior, Animal; Carbachol; Female; Functional Laterality; Male; Mecamylamine; Orientation; Physostigmine; Rats; Receptors, Cholinergic; Reticular Formation; Rotation; Scopolamine; Superior Colliculi | 1983 |
Muscarinic cholinergic mediation of opiate and non-opiate environmentally induced analgesias.
Topics: Analgesia; Animals; Central Nervous System; Cholinergic Fibers; Conditioning, Classical; Electroshock; Male; Mecamylamine; N-Methylscopolamine; Pain; Rats; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives | 1984 |
Scopolamine self-administration: cholinergic involvement in reward mechanisms.
Topics: Animals; Arecoline; Atropine; Behavior, Animal; Female; Mecamylamine; N-Methylscopolamine; Oxotremorine; Parasympathetic Nervous System; Physostigmine; Pilocarpine; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Reward; Scopolamine; Scopolamine Derivatives; Self Administration | 1982 |
Age-associated impairments in a test of attention: evidence for involvement of cholinergic systems.
Topics: Aging; Animals; Attention; Behavior, Animal; Cholinergic Agents; Exploratory Behavior; Male; Mecamylamine; Motor Activity; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Reaction Time; Scopolamine; Tacrine | 1995 |
Working memory performance and cholinergic effects in the ventral tegmental area and substantia nigra.
Topics: Acetylcholine; Alkaloids; Animals; Azocines; Female; Maze Learning; Mecamylamine; Memory; Nicotine; Pilocarpine; Psychomotor Performance; Quinolizines; Rats; Rats, Sprague-Dawley; Scopolamine; Substantia Nigra; Ventral Tegmental Area | 1994 |
Evidence that nicotine can acutely desensitize central nicotinic acetylcholinergic receptors.
Topics: Animals; Discrimination Learning; Discrimination, Psychological; Drug Tolerance; Injections, Subcutaneous; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Physostigmine; Rats; Rats, Sprague-Dawley; Scopolamine | 1994 |
Mecamylamine reverses physostigmine-induced attenuation of scopolamine-induced hyperactivity.
Topics: Animals; Hexamethonium; Hyperkinesis; Male; Mecamylamine; Motor Activity; Muscarinic Antagonists; Nicotine; Nicotinic Antagonists; Physostigmine; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine | 1994 |
Effects of ZK 93426 on muscarinic and nicotinic antagonist or nucleus basalis lesioning-induced electrocortical slowing.
Topics: Animals; Basal Ganglia; Carbolines; Cerebral Cortex; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Electroencephalography; GABA-A Receptor Antagonists; Male; Mecamylamine; Muscarinic Antagonists; Nicotinic Antagonists; Quisqualic Acid; Rats; Rats, Wistar; Scopolamine | 1993 |
Nicotine reverses scopolamine-induced impairment of performance in passive avoidance task in rats through its action on the dopaminergic neuronal system.
Topics: Animals; Avoidance Learning; Benzazepines; Dopamine; Dopamine D2 Receptor Antagonists; Male; Mecamylamine; Neurons; Nicotine; Rats; Rats, Wistar; Receptors, Dopamine D1; Scopolamine; Sulpiride | 1994 |
Comparative behavioral and neurochemical activities of cholinergic antagonists in rats.
Topics: Acetylcholine; Animals; Behavior, Animal; Brain Stem; Cerebral Cortex; Dopamine; Male; Mecamylamine; Memory; Neurotransmitter Agents; Parasympatholytics; Pirenzepine; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Receptors, Muscarinic; Scopolamine; Trihexyphenidyl | 1993 |
Nicotinic and muscarinic modulations of excitatory synaptic transmission in the rat prefrontal cortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Atropine; Bungarotoxins; Cerebral Cortex; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Evoked Potentials; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Mecamylamine; Membrane Potentials; Muscarine; Neurons; Nicotine; Pirenzepine; Pyramidal Tracts; Quinoxalines; Rats; Rats, Sprague-Dawley; Scopolamine; Synaptic Transmission; Tubocurarine | 1993 |
Modification of neocortical acetylcholine release and electroencephalogram desynchronization due to brainstem stimulation by drugs applied to the basal forebrain.
Topics: Acetylcholine; Anesthesia, General; Animals; Brain Mapping; Brain Stem; Cholinergic Antagonists; Electroencephalography; Female; Kynurenic Acid; Magnesium; Mecamylamine; Microdialysis; Procaine; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Receptors, Glutamate; Scopolamine; Substantia Innominata; Tegmentum Mesencephali; Tetrodotoxin; Urethane | 1994 |
Glucose attenuates the effect of combined muscarinic-nicotinic receptor blockade on spontaneous alternation.
Topics: Animals; Behavior, Animal; Glucose; Male; Mecamylamine; Memory; Mice; Mice, Inbred ICR; Muscarinic Antagonists; Nicotinic Antagonists; Scopolamine | 1994 |
Effects of concomitant nicotinic and muscarinic blockade on spatial memory disturbance in rats are purely additive: evidence from the Morris water task.
Topics: Animals; Brain; Discrimination Learning; Dose-Response Relationship, Drug; Drug Synergism; Escape Reaction; Male; Mecamylamine; Mental Recall; Orientation; Rats; Rats, Inbred F344; Receptors, Muscarinic; Receptors, Nicotinic; Retention, Psychology; Scopolamine | 1994 |
Reticular facilitation of cat visual cortical responses is mediated by nicotinic and muscarinic cholinergic mechanisms.
Topics: Animals; Atropine; Cats; Electric Stimulation; Evoked Potentials, Visual; Injections, Intravenous; Mecamylamine; Muscarinic Antagonists; Nicotinic Antagonists; Parasympathetic Nervous System; Receptors, Muscarinic; Receptors, Nicotinic; Reticular Formation; Scopolamine; Visual Cortex | 1993 |
Cholinergic drugs regulate passive avoidance performance via the amygdala.
Topics: Amygdala; Animals; Arecoline; Avoidance Learning; Behavior, Animal; Brain Diseases; Male; Mecamylamine; Muscarinic Antagonists; Nicotine; Nicotinic Antagonists; Parasympathomimetics; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine; Substantia Innominata | 1993 |
Differential effects of scopolamine and mecamylamine on working and reference memory in the rat.
Topics: Animals; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Male; Mecamylamine; Memory; Memory, Short-Term; Rats; Rats, Sprague-Dawley; Reward; Scopolamine | 1993 |
Effects of an inhibitor of GABA-aminotransferase (gamma-vinyl-GABA) on the spatial navigation deficit induced by nicotinic blockade.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; gamma-Aminobutyric Acid; Male; Mecamylamine; Memory; Nicotinic Antagonists; Orientation; Parasympathetic Nervous System; Rats; Rats, Wistar; Scopolamine; Space Perception; Vigabatrin | 1993 |
Cholinergic effects on cat retina In vitro: changes in rod- and cone-driven b-wave and optic nerve response.
Topics: Acetylcholine; Action Potentials; Animals; Carbachol; Cats; Cholinergic Agonists; Cholinergic Antagonists; Electroretinography; In Vitro Techniques; Mecamylamine; Optic Nerve; Photoreceptor Cells; Quinuclidinyl Benzilate; Retina; Scopolamine; Time Factors | 1996 |
Acute and chronic nicotine effects on working memory in aged rats.
Topics: Age Factors; Aging; Animals; Dose-Response Relationship, Drug; Haloperidol; Male; Maze Learning; Mecamylamine; Memory; Nicotine; Rats; Rats, Sprague-Dawley; Scopolamine | 1996 |
The effect of muscarinic and nicotinic ACh antagonist on the facilitation of rat visual cortical responses.
Topics: Animals; Atropine; Male; Mecamylamine; Muscarinic Antagonists; Nicotinic Antagonists; Rats; Rats, Wistar; Reticular Formation; Scopolamine; Visual Cortex | 1996 |
Nicotinic, muscarinic and dopaminergic actions in the ventral hippocampus and the nucleus accumbens: effects on spatial working memory in rats.
Topics: Animals; Female; Hippocampus; Maze Learning; Mecamylamine; Memory; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nucleus Accumbens; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine | 1996 |
Effects of cholinergic agents on locomotor activity of P and NP rats.
Topics: Alcohol Drinking; Animals; Arousal; Brain; Cholinergic Agents; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Mecamylamine; Motor Activity; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine | 1996 |
Cognitive effects of neonatal hippocampal lesions in a rat model of schizophrenia.
Topics: Amphetamine; Animals; Behavior, Animal; Brain Diseases; Central Nervous System Stimulants; Disease Models, Animal; Female; Hippocampus; Ibotenic Acid; Male; Maze Learning; Mecamylamine; Memory; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Random Allocation; Rats; Rats, Sprague-Dawley; Schizophrenia; Schizophrenic Psychology; Scopolamine | 1996 |
Additive deficits in the choice accuracy of rats in the delayed non-matching to position task after cholinolytics and serotonergic lesions are non-mnemonic in nature.
Topics: 5,7-Dihydroxytryptamine; Animals; Brain; Hexamethonium; Male; Mecamylamine; Memory; Muscarinic Antagonists; Nicotinic Antagonists; Rats; Rats, Wistar; Scopolamine; Serotonin | 1997 |
Mecamylamine- or scopolamine-induced learning impairment: ameliorated by nefiracetam.
Topics: Animals; Dose-Response Relationship, Drug; Female; Learning; Mecamylamine; Nootropic Agents; Pyrrolidinones; Rabbits; Reaction Time; Scopolamine | 1997 |
Nicotine-induced decreases in VTA electrical self-stimulation thresholds: blockade by haloperidol and mecamylamine but not scopolamine or ondansetron.
Topics: Animals; Conditioning, Operant; Dopamine Antagonists; Haloperidol; Male; Mecamylamine; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Ondansetron; Rats; Rats, Sprague-Dawley; Scopolamine; Self Stimulation; Serotonin Antagonists; Ventral Tegmental Area | 1997 |
Effects of physostigmine on the startle in guinea pigs: two mechanisms involved.
Topics: Acoustic Stimulation; Animals; Cholinergic Antagonists; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Guinea Pigs; Male; Mecamylamine; Motor Activity; Muscarinic Antagonists; Physostigmine; Reflex, Startle; Scopolamine | 1997 |
The role of the dorsal raphe-serotonergic system and cholinergic receptors in the modulation of working memory.
Topics: Animals; Biogenic Monoamines; Cholinergic Antagonists; Fenclonine; Hexamethonium Compounds; Male; Mecamylamine; Memory, Short-Term; Muscarinic Antagonists; Nicotinic Antagonists; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Cholinergic; Scopolamine; Serotonin | 1998 |
Effects of U-50,488H on scopolamine-, mecamylamine- and dizocilpine-induced learning and memory impairment in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetylcholine; Animals; Dizocilpine Maleate; Dynorphins; Learning Disabilities; Male; Mecamylamine; Memory Disorders; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Scopolamine | 1998 |
Rivastigmine, a brain-selective acetylcholinesterase inhibitor, ameliorates cognitive and motor deficits induced by closed-head injury in the mouse.
Topics: Animals; Brain Edema; Carbamates; Cholinergic Antagonists; Cholinesterase Inhibitors; Cognition Disorders; Head Injuries, Closed; Male; Maze Learning; Mecamylamine; Memory; Mice; Movement; Movement Disorders; Muscarinic Antagonists; Neuroprotective Agents; Phenylcarbamates; Rivastigmine; Scopolamine | 1998 |
5-[I-125/123]lodo-3(2(S)-azetidinylmethoxy)pyridine, a radioiodinated analog of A-85380 for in vivo studies of central nicotinic acetylcholine receptors.
Topics: Alkaloids; Animals; Azetidines; Azocines; Binding Sites; Brain; Dose-Response Relationship, Drug; Iodine Radioisotopes; Male; Mecamylamine; Mice; Muscarinic Antagonists; Nicotine; Nicotinic Antagonists; Quinolizines; Radionuclide Imaging; Receptors, Nicotinic; Scopolamine; Tissue Distribution | 1998 |
The cholinergic basis of the smoking-induced EEG activation profile.
Topics: Adult; Analysis of Variance; Arousal; Cerebral Cortex; Cholinergic Fibers; Electroencephalography; Humans; Male; Mecamylamine; Middle Aged; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Scopolamine; Sensation; Smoking | 1998 |
Acute nicotine interactions with nicotinic and muscarinic antagonists: working and reference memory effects in the 16-arm radial maze.
Topics: Animals; Drug Interactions; Female; Maze Learning; Mecamylamine; Memory, Short-Term; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Scopolamine | 1997 |
Cholinergic and GABAergic regulation of nitric oxide synthesis in the guinea pig ileum.
Topics: Animals; Baclofen; Bicuculline; Cholinergic Agonists; Cholinergic Antagonists; Citrulline; Egtazic Acid; Electric Stimulation; Female; GABA Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Isometric Contraction; Male; Mecamylamine; Muscimol; Muscle, Smooth; Myenteric Plexus; Nitric Oxide; Nitroarginine; Oxotremorine; Scopolamine; Tetrodotoxin; Tubocurarine | 1999 |
The allocentric place discrimination task is selectively and highly dependent on the central muscarinic system in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Diazepam; Discrimination Learning; Dizocilpine Maleate; Flumazenil; Male; Mecamylamine; Ondansetron; Rats; Rats, Inbred F344; Receptors, Muscarinic; Scopolamine; Swimming | 2000 |
The role of nicotinic and muscarinic acetylcholine receptors in attention.
Topics: Animals; Attention; Male; Mecamylamine; Oxotremorine; Physostigmine; Rats; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine | 2000 |
Nicotine in an animal model of attention.
Topics: Animals; Attention; Cognition; Drug Interactions; Female; Male; Mecamylamine; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Psychomotor Performance; Rats; Reaction Time; Scopolamine | 2000 |
Design, synthesis, and preliminary pharmacological evaluation of 1, 4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic agents.
Topics: Adrenergic alpha-Agonists; Amnesia; Animals; Avoidance Learning; Baclofen; Clonidine; Dose-Response Relationship, Drug; Drug Design; GABA Agonists; Mecamylamine; Mice; Molecular Structure; Muscarinic Antagonists; Nicotine; Nootropic Agents; Piperazines; Piracetam; Pyrroles; Scopolamine | 2000 |
Cerebral cortical muscarinic cholinergic and N-methyl-D-aspartate receptors mediate increase in cortical blood flow elicited by chemical stimulation of periaqueductal gray matter.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Animals; Blood Pressure; Cerebral Cortex; Cerebrovascular Circulation; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Mecamylamine; Muscarinic Antagonists; N-Methylaspartate; Nicotinic Antagonists; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Scopolamine; Stimulation, Chemical; Vasodilation; Vasodilator Agents | 2000 |
Muscarinic cholinergic modulation of prepulse inhibition of the acoustic startle reflex.
Topics: Acoustic Stimulation; Animals; Cholinesterase Inhibitors; Male; Mecamylamine; Muscarinic Agonists; Muscarinic Antagonists; Nicotinic Antagonists; Oxotremorine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Reflex; Reflex, Startle; Scopolamine; Structure-Activity Relationship | 2000 |
Laterodorsal tegmental stimulation elicits dopamine efflux in the rat nucleus accumbens by activation of acetylcholine and glutamate receptors in the ventral tegmental area.
Topics: Animals; Cholinergic Fibers; Diamines; Dopamine; Electric Stimulation; Kynurenic Acid; Male; Mecamylamine; Neural Pathways; Neurons; Nucleus Accumbens; Parasympatholytics; Pons; Rats; Rats, Wistar; Receptors, Cholinergic; Receptors, Glutamate; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine; Stereotaxic Techniques; Ventral Tegmental Area | 2000 |
Effects of Uncaria tomentosa total alkaloid and its components on experimental amnesia in mice: elucidation using the passive avoidance test.
Topics: Alkaloids; Amnesia; Animals; Avoidance Learning; Cat's Claw; Diazepam; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Excitatory Amino Acid Antagonists; GABA Modulators; Indole Alkaloids; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mecamylamine; Mice; Motor Activity; Muscarinic Agonists; Muscarinic Antagonists; Nicotinic Antagonists; Oxindoles; Oxotremorine; Piperazines; Pirenzepine; Plants, Medicinal; Scopolamine | 2000 |
Sexual diergism in rat hypothalamic-pituitary-adrenal axis responses to cholinergic stimulation and antagonism.
Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Cholinesterase Inhibitors; Corticosterone; Female; Hypothalamo-Hypophyseal System; Male; Mecamylamine; Muscarinic Antagonists; Nicotinic Antagonists; Physostigmine; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Scopolamine; Sex Characteristics | 2001 |
Reversal caused by n-butylidenephthalide from the deficits of inhibitory avoidance performance in rats.
Topics: Animals; Avoidance Learning; Cholinergic Antagonists; Male; Mecamylamine; Phthalic Anhydrides; Piracetam; Rats; Rats, Sprague-Dawley; Scopolamine | 2001 |
Interaction between the cholinergic system and CRH in the modulation of spatial discrimination learning in mice.
Topics: Acetylcholine; Animals; Brain; Cholinergic Fibers; Corticotropin-Releasing Hormone; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Male; Maze Learning; Mecamylamine; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Neurons; Nicotinic Antagonists; Reaction Time; Scopolamine; Space Perception; Touch | 2001 |
The effects of physostigmine and cholinergic receptor ligands on novelty-induced neophobia.
Topics: Animals; Anxiety; Cerebral Ventricles; Cholinergic Agonists; Cholinesterase Inhibitors; Exploratory Behavior; Gallamine Triethiodide; Injections, Intraventricular; Ligands; Male; Mecamylamine; Microinjections; Motor Activity; Muscarinic Agonists; Nicotine; Nicotinic Agonists; Physostigmine; Pirenzepine; Rats; Rats, Wistar; Receptors, Cholinergic; Scopolamine | 2000 |
Memory impairment induced by cholinergic antagonists injected into the mushroom bodies of the honeybee.
Topics: Animals; Bees; Behavior, Animal; Conditioning, Psychological; Male; Mecamylamine; Memory; Muscarinic Antagonists; Mushroom Bodies; Nicotinic Antagonists; Receptors, Cholinergic; Scopolamine; Smell | 2001 |
Persistent behavioral consequences of neonatal chlorpyrifos exposure in rats.
Topics: Animals; Animals, Newborn; Behavior, Animal; Chlorpyrifos; Female; Insecticides; Male; Maze Learning; Mecamylamine; Memory; Motor Activity; Muscarinic Antagonists; Nicotinic Antagonists; Pregnancy; Rats; Rats, Sprague-Dawley; Scopolamine | 2001 |
Cholinergic neuronal modulations affect striatal dopamine transporter activity: PET studies in the conscious monkey brain.
Topics: Animals; Cholinergic Fibers; Consciousness; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Macaca mulatta; Male; Mecamylamine; Membrane Glycoproteins; Membrane Transport Proteins; Muscarinic Antagonists; Nerve Tissue Proteins; Nicotinic Antagonists; Scopolamine; Tomography, Emission-Computed | 2001 |
Differential roles for nicotinic and muscarinic cholinergic receptors in sustained visuo-spatial attention? A study using a 5-arm maze protocol in mice.
Topics: Animals; Attention; Male; Maze Learning; Mecamylamine; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Nicotinic Antagonists; Psychomotor Performance; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine; Space Perception | 2002 |
Effects of puerarin on scopolamine-, mecamylamine-, p-chloroamphetamine- and dizocilpine-induced inhibitory avoidance performance impairment in rats.
Topics: Amnesia; Animals; Avoidance Learning; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Isoflavones; Male; Mecamylamine; p-Chloroamphetamine; Phytotherapy; Pueraria; Random Allocation; Rats; Rats, Sprague-Dawley; Scopolamine | 2002 |
Residential maze as a task for testing rats' maze learning ability: effects of hippocampal lesions and cholinergic receptor antagonists.
Topics: Animals; Dose-Response Relationship, Drug; Hippocampus; Male; Maze Learning; Mecamylamine; Memory; Muscarinic Antagonists; Neuropsychological Tests; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine | 2002 |
Cognitive enhancing properties and tolerability of cholinergic agents in mice: a comparative study of nicotine, donepezil, and SIB-1553A, a subtype-selective ligand for nicotinic acetylcholine receptors.
Topics: Age Factors; Animals; Attention; Behavior, Animal; Choice Behavior; Cholinesterase Inhibitors; Cognition; Discrimination Learning; Donepezil; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Indans; Lethal Dose 50; Male; Mecamylamine; Memory, Short-Term; Mice; Mice, Inbred C57BL; Motor Activity; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phenols; Piperidines; Psychomotor Performance; Pyrrolidines; Reaction Time; Receptors, Nicotinic; Scopolamine; Seizures | 2003 |
Castration in rats impairs performance during acquisition of a working memory task and exacerbates deficits in working memory produced by scopolamine and mecamylamine.
Topics: Animals; Dose-Response Relationship, Drug; Ganglionic Blockers; Male; Maze Learning; Mecamylamine; Memory Disorders; Muscarinic Antagonists; Orchiectomy; Rats; Scopolamine; Testicular Hormones | 2003 |
Role of central cholinergic receptor sub-types in spatial working memory: a five-arm maze task in mice provides evidence for a functional role of nicotinic receptors in mediating trace access processes.
Topics: Animals; Behavior, Animal; Central Nervous System; Drug Interactions; Male; Maze Learning; Mecamylamine; Memory, Short-Term; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Nicotinic Antagonists; Reaction Time; Receptors, Cholinergic; Retention, Psychology; Scopolamine; Spatial Behavior; Time Factors | 2003 |
Effects of drugs which depress the peripheral nervous system on the reticular activating system of the cat.
Topics: Acetylcholine; Animals; Atropine; Brain Stem; Cats; Choline; Dihydro-beta-Erythroidine; Humans; Mecamylamine; Nicotine; Peripheral Nervous System; Physostigmine; Scopolamine | 1958 |
THE SITE OF THE 5-HYDROXYTRYPTAMINE RECEPTOR ON THE INTRAMURAL NERVOUS PLEXUS OF THE GUINEA-PIG ISOLATED ILEUM.
Topics: Acetylcholine; Animals; Autonomic Nervous System; Choline; Ganglia; Ganglia, Autonomic; Ganglionic Blockers; Guinea Pigs; Hexamethonium Compounds; Histamine; Ileum; Isoflurophate; Lysergic Acid Diethylamide; Mecamylamine; Muscle, Smooth; Nicotine; Organophosphate Poisoning; Pempidine; Pentolinium Tartrate; Pharmacology; Phenoxybenzamine; Phosphorus; Poisons; Procaine; Receptors, Serotonin; Research; Scopolamine; Serotonin | 1963 |
PREGANGLIONIC AND POSTGANGLIONIC STIMULATION OF THE GUINEA-PIG ISOLATED VAS DEFERENS PREPARATION.
Topics: Acetylcholine; Animals; Atropine; Bretylium Compounds; Dextroamphetamine; Electric Stimulation; Electrophysiology; Ergotamine; Ganglia; Ganglia, Spinal; Ganglionic Blockers; Guanethidine; Guinea Pigs; Hexamethonium Compounds; Humans; Lidocaine; Male; Mecamylamine; Nicotine; Norepinephrine; Pentolinium Tartrate; Pharmacology; Phentolamine; Potassium; Procaine; Research; Scopolamine; Vas Deferens | 1963 |
THE ACTION OF PEMPIDINE AND ANTIADRENALINE SUBSTANCES AT THE SYMPATHETIC POSTGANGLIONIC TERMINATION.
Topics: Abdominal Wall; Acetylcholine; Animals; Anura; Cholinesterase Inhibitors; Dihydroergotoxine; Electrophysiology; Ergot Alkaloids; Ganglia; Ganglia, Autonomic; Guinea Pigs; Humans; Hypogastric Plexus; Ileum; Male; Mecamylamine; Muscle Contraction; Muscles; Neostigmine; Pempidine; Pharmacology; Phentolamine; Physostigmine; Rabbits; Research; Scopolamine; Sympathetic Nervous System; Sympatholytics; Vas Deferens; Yohimbine | 1965 |
Norleucine1-Angiotensin IV alleviates mecamylamine-induced spatial memory deficits.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Male; Maze Learning; Mecamylamine; Memory; Memory Disorders; Norleucine; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Scopolamine | 2004 |
Neurogenic vasodilation of dural blood vessels is not mediated by cholinergic transmission in the anaesthetised rat.
Topics: Acetylcholine; Animals; Cholinergic Fibers; Drug Administration Schedule; Dura Mater; Electric Stimulation; Injections, Intravenous; Male; Mecamylamine; Meningeal Arteries; Microscopy; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine; Trigeminal Nerve; Vasodilation | 2004 |
Nucleus accumbens acetylcholine regulates appetitive learning and motivation for food via activation of muscarinic receptors.
Topics: Acetylcholine; Analysis of Variance; Animals; Appetitive Behavior; Behavior, Animal; Conditioning, Operant; Dose-Response Relationship, Drug; Food; Male; Mecamylamine; Motivation; Motor Activity; Muscarinic Antagonists; Nicotinic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Muscarinic; Reinforcement, Psychology; Scopolamine | 2004 |
Effect of vitamin E on memory retention in rats: possible involvement of cholinergic system.
Topics: Animals; Cerebral Ventricles; Conditioning, Operant; Injections, Intraventricular; Male; Mecamylamine; Memory; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Parasympathetic Nervous System; Pilocarpine; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine; Vitamin E; Vitamins | 2006 |
Roles of pedunculopontine tegmental cholinergic receptors in brain stimulation reward in the rat.
Topics: Acetylcholine; Animals; Drug Interactions; Hypothalamic Area, Lateral; Mecamylamine; Muscarinic Antagonists; Nicotinic Antagonists; Pedunculopontine Tegmental Nucleus; Rats; Rats, Wistar; Receptors, Cholinergic; Reward; Scopolamine; Self Stimulation | 2006 |
Protective effect of donepezil on retinal ganglion cells in vitro and in vivo.
Topics: Administration, Oral; Animals; Axotomy; Benzopyrans; Cell Survival; Cells, Cultured; Cholinergic Antagonists; Cholinesterase Inhibitors; Cytoprotection; Donepezil; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Glutamic Acid; Indans; Mecamylamine; Neuroprotective Agents; Nitriles; Optic Nerve Injuries; Piperidines; Rats; Retinal Ganglion Cells; Scopolamine | 2006 |
Nicotinic mechanisms contribute to soman-induced symptoms and lethality.
Topics: Acetylcholinesterase; Analysis of Variance; Animals; Behavior, Animal; Chemical Warfare Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Hyperkinesis; Lethal Dose 50; Mecamylamine; Mice; Muscarinic Antagonists; Muscle Rigidity; Nicotine; Nicotinic Antagonists; Poisoning; Scopolamine; Soman; Time Factors; Tremor | 2006 |
Blockade of muscarinic acetylcholine receptors in the ventral tegmental area prevents acquisition of food-rewarded operant responding in rats.
Topics: Animals; Conditioning, Operant; Food; Male; Mecamylamine; Muscarinic Antagonists; Nicotinic Antagonists; Rats; Rats, Long-Evans; Reward; Scopolamine; Ventral Tegmental Area | 2006 |
Suppression of methamphetamine-seeking behavior by nicotinic agonists.
Topics: Acetylcholinesterase; Animals; Behavior, Animal; Brain; Cholinesterase Inhibitors; Donepezil; Indans; Lidocaine; Male; Mecamylamine; Methamphetamine; Nicotine; Nicotinic Agonists; Piperidines; Rats; Rats, Wistar; Receptors, Nicotinic; Scopolamine | 2006 |
Strain specificity and cholinergic modulation of visuospatial attention in three inbred mouse strains.
Topics: Animals; Attention; Choice Behavior; Cholinergic Agents; Cholinergic Fibers; Male; Maze Learning; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Nicotine; Receptors, Cholinergic; Scopolamine; Serial Learning; Space Perception; Spatial Behavior; Species Specificity | 2007 |
Evaluation of muscarinic and nicotinic receptor antagonists on attention and working memory.
Topics: Animals; Attention; Discrimination Learning; Drug Interactions; Male; Mecamylamine; Memory; Muscarinic Antagonists; Nicotinic Antagonists; Rats; Rats, Long-Evans; Scopolamine; Visual Perception | 2006 |
Nicotinic facilitation of delta9-tetrahydrocannabinol discrimination involves endogenous anandamide.
Topics: Animals; Arachidonic Acids; Discrimination, Psychological; Dose-Response Relationship, Drug; Dronabinol; Drug Synergism; Endocannabinoids; Enzyme Inhibitors; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mecamylamine; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pilocarpine; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Cannabinoid, CB1; Receptors, Muscarinic; Receptors, Nicotinic; Reinforcement, Psychology; Scopolamine | 2007 |
Involvement of M1-muscarinic acetylcholine receptors, protein kinase C and mitogen-activated protein kinase in the effect of huperzine A on secretory amyloid precursor protein-alpha.
Topics: Alkaloids; Cell Line; Cholinesterase Inhibitors; Enzyme Inhibitors; Humans; Mecamylamine; Mitogen-Activated Protein Kinases; Muscarinic Antagonists; Nicotinic Antagonists; Protein Kinase C; Receptor, Muscarinic M1; Scopolamine; Serum Amyloid A Protein; Sesquiterpenes; Up-Regulation | 2007 |
Participation of cholinergic system in memory deficits induced by blockade of hippocampal mGlu(1) receptors.
Topics: Animals; Cholinergic Agents; Cholinergic Antagonists; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hippocampus; Indans; Male; Maze Learning; Mecamylamine; Memory Disorders; Piperidines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Scopolamine | 2007 |
Cholinergic modulation of visuospatial responding in central thalamus.
Topics: Animals; Behavior, Animal; Choice Behavior; Cholinergic Antagonists; Dose-Response Relationship, Drug; Drug Combinations; GABA Agonists; Injections; Injections, Subcutaneous; Light; Male; Mecamylamine; Muscimol; Nicotinic Antagonists; Rats; Rats, Long-Evans; Reaction Time; Scopolamine; Space Perception; Thalamus; Visual Perception | 2007 |
Nicotinic versus muscarinic blockade alters verbal working memory-related brain activity in older women.
Topics: Aged; Brain; Educational Status; Female; Humans; Magnetic Resonance Imaging; Mecamylamine; Memory; Middle Aged; Muscarinic Antagonists; Nicotinic Antagonists; Postmenopause; Psychiatric Status Rating Scales; Scopolamine; Speech | 2008 |
Midbrain acetylcholine and glutamate receptors modulate accumbal dopamine release.
Topics: Animals; Cholinergic Antagonists; Dopamine; Electric Stimulation; Electrochemistry; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; Mecamylamine; Mesencephalon; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Receptors, Cholinergic; Receptors, Glutamate; Scopolamine; Ventral Tegmental Area | 2008 |
Cellular and synaptic actions of acetylcholine in the lamprey spinal cord.
Topics: Acetylcholine; Animals; Choline O-Acetyltransferase; Cholinergic Agents; Electric Stimulation; Glycine Agents; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Lampreys; Mecamylamine; Motor Neurons; Oxotremorine; Patch-Clamp Techniques; Scopolamine; Sodium Channel Blockers; Spinal Cord; Strychnine; Synapses; Tetrodotoxin | 2008 |
Cholinergic mechanism underlying prepulse inhibition of the startle response in rats.
Topics: Acetylcholine; Acoustic Stimulation; Amino Acids; Analysis of Variance; Animals; Animals, Newborn; Cholinergic Antagonists; Electric Stimulation; Excitatory Postsynaptic Potentials; In Vitro Techniques; Mecamylamine; Mesencephalon; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Reflex, Startle; Scopolamine | 2008 |
Acetylcholine contributes through muscarinic receptors to attentional modulation in V1.
Topics: Acetylcholine; Animals; Attention; Cholinergic Antagonists; Macaca mulatta; Magnetic Resonance Imaging; Male; Mecamylamine; Muscarinic Antagonists; Nicotinic Antagonists; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine | 2008 |
Blockade of NMDA receptors in the prefrontal cortex increases dopamine and acetylcholine release in the nucleus accumbens and motor activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cholinergic Antagonists; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Flupenthixol; Glutamic Acid; Homovanillic Acid; Injections, Intraventricular; Male; Mecamylamine; Microinjections; Motor Activity; Muscarinic Antagonists; N-Methylaspartate; Nicotinic Antagonists; Nucleus Accumbens; Piperazines; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Scopolamine | 2008 |
Alternating low frequency stimulation of medial septal and commissural fibers induces NMDA-dependent, long-lasting potentiation of hippocampal synapses in urethane-anesthetized rats.
Topics: Anesthetics, Intravenous; Animals; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Male; Mecamylamine; Muscarinic Antagonists; N-Methylaspartate; Nicotinic Antagonists; Rats; Rats, Long-Evans; Scopolamine; Septum of Brain; Synapses; Urethane; Valine | 2009 |
Participation of the cholinergic system in ameliorating effect of vasopressin fragment by group I metabotropic glutamate-receptor blockade.
Topics: Animals; Arginine Vasopressin; Behavior, Animal; Cholinergic Fibers; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hippocampus; Indans; Male; Maze Learning; Mecamylamine; Memory; Muscarinic Antagonists; Nicotinic Antagonists; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Muscarinic; Scopolamine | 2008 |
Attenuation of pharmacologically-induced attentional impairment by methylphenidate in rats.
Topics: Animals; Attention; Central Nervous System Stimulants; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Mecamylamine; Methylphenidate; Muscarinic Antagonists; Nicotinic Antagonists; Photic Stimulation; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Scopolamine; Signal Detection, Psychological; Visual Perception | 2009 |
Original nootropic drug noopept prevents memory deficit in rats with muscarinic and nicotinic receptor blockade.
Topics: Animals; Cholinergic Agonists; Cholinergic Antagonists; Dipeptides; Male; Mecamylamine; Memory; Memory Disorders; Nicotinic Antagonists; Nootropic Agents; Rats; Scopolamine | 2008 |
The role of the AT4 and cholinergic systems in the Nucleus Basalis Magnocellularis (NBM): effects on spatial memory.
Topics: Acetylcholine; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Basal Nucleus of Meynert; Behavior, Animal; Carbachol; Cholinergic Antagonists; Dose-Response Relationship, Drug; Male; Maze Learning; Mecamylamine; Memory; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Angiotensin; Scopolamine; Spatial Behavior; Time Factors | 2009 |
A novel touchscreen-automated paired-associate learning (PAL) task sensitive to pharmacological manipulation of the hippocampus: a translational rodent model of cognitive impairments in neurodegenerative disease.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Behavioral Research; Cholinergic Antagonists; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Lidocaine; Male; Mecamylamine; Neuropsychological Tests; Paired-Associate Learning; Rats; Reaction Time; Scopolamine | 2009 |
Cholinergic pairing with visual activation results in long-term enhancement of visual evoked potentials.
Topics: Acetylcholine; Animals; Evoked Potentials, Visual; Long-Term Potentiation; Mecamylamine; Models, Biological; N-Methylaspartate; Rats; Rats, Long-Evans; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine; Time Factors; Vision, Ocular; Visual Cortex | 2009 |
Selective potentiation of crossed vs. uncrossed inputs from lateral geniculate nucleus to visual cortex by the basal forebrain: potential facilitation of rodent binocularity.
Topics: Acetylcholine; Animals; Electric Stimulation; Geniculate Bodies; Male; Mecamylamine; Muscarinic Antagonists; Neuronal Plasticity; Nicotinic Antagonists; Prosencephalon; Rats; Rats, Long-Evans; Scopolamine; Synapses; Synaptic Potentials; Vision, Binocular; Visual Cortex | 2009 |
The role of nicotinic receptors in the amelioration of cholinesterase inhibitors in scopolamine-induced memory deficits.
Topics: Animals; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Indans; Learning Disabilities; Male; Maze Learning; Mecamylamine; Muscarinic Agonists; Nicotine; Nicotinic Antagonists; Physostigmine; Pilocarpine; Piperidines; Rats; Rats, Wistar; Receptors, Nicotinic; Scopolamine; Theta Rhythm | 2009 |
The beneficial effects of estradiol on attentional processes are dependent on timing of treatment initiation following ovariectomy in middle-aged rats.
Topics: Age Factors; Animals; Attention; Choice Behavior; Cholinergic Antagonists; Drug Administration Schedule; Drug Implants; Estradiol; Estrogen Replacement Therapy; Female; Mecamylamine; Ovariectomy; Rats; Rats, Long-Evans; Scopolamine; Time Factors | 2010 |
Motor activity-induced dopamine release in the substantia nigra is regulated by muscarinic receptors.
Topics: Analysis of Variance; Animals; Area Under Curve; Brain Injuries; Chromatography, High Pressure Liquid; Dendrites; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Electrochemistry; Female; Functional Laterality; gamma-Aminobutyric Acid; Mecamylamine; Microdialysis; Motor Activity; Muscarinic Antagonists; Nicotinic Antagonists; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Rotarod Performance Test; Scopolamine; Substantia Nigra | 2010 |
Subtype-selective nicotinic agonists enhance olfactory working memory in normal rats: a novel use of the odour span task.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Azabicyclo Compounds; Male; Mecamylamine; Memory, Short-Term; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Odorants; Olfactory Perception; Rats; Receptors, Nicotinic; Scopolamine; Thiophenes | 2010 |
Modulatory action of acetylcholine on the Na+-dependent action potentials in Kenyon cells isolated from the mushroom body of the cricket brain.
Topics: Acetylcholine; Action Potentials; Amphotericin B; Animals; Atropine; Brain; Cholinergic Antagonists; Gryllidae; Male; Mecamylamine; Mushroom Bodies; Neurons; Nicotinic Antagonists; Patch-Clamp Techniques; Scopolamine | 2010 |
Effects of adjunct galantamine to risperidone, or haloperidol, in animal models of antipsychotic activity and extrapyramidal side-effect liability: involvement of the cholinergic muscarinic receptor.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Behavior, Animal; Catalepsy; Cholinergic Antagonists; Cholinesterase Inhibitors; Disease Models, Animal; Extrapyramidal Tracts; Galantamine; Haloperidol; Male; Mecamylamine; Motor Activity; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Muscarinic; Risperidone; Schizophrenia; Scopolamine | 2011 |
Cholinergic interneurons mediate fast VGluT3-dependent glutamatergic transmission in the striatum.
Topics: Amino Acid Transport Systems, Acidic; Animals; Central Nervous System Stimulants; Channelrhodopsins; Corpus Striatum; Evoked Potentials; Female; Interneurons; Male; Mecamylamine; Mice; Picrotoxin; Receptors, Cholinergic; Receptors, N-Methyl-D-Aspartate; Scopolamine | 2011 |
Beneficial effects of resveratrol on scopolamine but not mecamylamine induced memory impairment in the passive avoidance and Morris water maze tests in rats.
Topics: Animals; Avoidance Learning; Male; Maze Learning; Mecamylamine; Memory Disorders; Rats; Rats, Wistar; Reaction Time; Resveratrol; Scopolamine; Stilbenes | 2011 |
Selective inhibition of striatal fast-spiking interneurons causes dyskinesias.
Topics: Action Potentials; Adamantane; Analysis of Variance; Animals; Area Under Curve; Cholinergic Antagonists; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesias; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Functional Laterality; Green Fluorescent Proteins; Interneurons; LIM-Homeodomain Proteins; Male; Mecamylamine; Mice; Mice, Transgenic; N-Methylaspartate; Nerve Tissue Proteins; Scopolamine; Transcription Factors | 2011 |
Possible interaction between opioidergic and cholinergic systems of CA1 in cholestasis-induced amnesia in mice.
Topics: Amnesia; Animals; Animals, Outbred Strains; CA1 Region, Hippocampal; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Exploratory Behavior; Male; Mecamylamine; Mental Recall; Mice; Microinjections; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nicotinic Antagonists; Receptors, Opioid; Scopolamine | 2012 |
Participation of hippocampal cholinergic system in memory persistence for inhibitory avoidance in rats.
Topics: Acetylcholine; Anesthetics, Local; Animals; Avoidance Learning; Hippocampus; Lidocaine; Male; Mecamylamine; Memory; Muscarinic Antagonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Cholinergic; Scopolamine; Septal Nuclei | 2012 |
Galantamine attenuates the heroin seeking behaviors induced by cues after prolonged withdrawal in rats.
Topics: Animals; Behavior, Animal; Cholinergic Antagonists; Cholinesterase Inhibitors; Cues; Drug-Seeking Behavior; Extinction, Psychological; Galantamine; Heroin; Mecamylamine; Motor Activity; Narcotics; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Scopolamine; Self Administration; Substance Withdrawal Syndrome; Ventral Tegmental Area | 2012 |
The nociceptin orphanin FQ peptide receptor agonist, Ro64-6198, impairs recognition memory formation through interaction with glutamatergic but not cholinergic receptor antagonists.
Topics: Animals; Cholinergic Antagonists; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Imidazoles; Male; Mecamylamine; Mice; Nociceptin Receptor; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Recognition, Psychology; Scopolamine; Spiro Compounds | 2012 |
Involvement of cholinergic receptors in the different stages of memory measured in the modified elevated plus maze test in mice.
Topics: Animals; Benzazepines; Male; Maze Learning; Mecamylamine; Memory; Mice; Motor Activity; Nicotine; Quinoxalines; Receptors, Cholinergic; Scopolamine; Varenicline | 2012 |
Cholinergic modulation during acquisition of olfactory fear conditioning alters learning and stimulus generalization in mice.
Topics: Analysis of Variance; Animals; Cholinergic Agents; Conditioning, Classical; Cues; Electroshock; Fear; Female; Freezing Reaction, Cataleptic; Generalization, Psychological; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Nicotinic Antagonists; Odorants; Olfactory Pathways; Scopolamine; Smell | 2012 |
The role of the cholinergic system in the signal attenuation rat model of obsessive-compulsive disorder.
Topics: Acetylcholine; Animals; Behavior, Animal; Compulsive Behavior; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Mecamylamine; Nicotine; Obsessive-Compulsive Disorder; Oxotremorine; Physostigmine; Rats; Rats, Sprague-Dawley; Scopolamine | 2013 |
Differential role of ventral tegmental area acetylcholine and N-methyl-D-aspartate receptors in cocaine-seeking.
Topics: Acetylcholine; Anesthetics, Local; Animals; Benzazepines; Cholinergic Antagonists; Cocaine; Cues; Dopamine; Dopamine Agonists; Drug-Seeking Behavior; Lidocaine; Male; Mecamylamine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Scopolamine; Time Factors; Valine; Ventral Tegmental Area | 2013 |
Hippocampal long term memory: effect of the cholinergic system on local protein synthesis.
Topics: Animals; Avoidance Learning; Hippocampus; Male; Mecamylamine; Memory, Long-Term; Memory, Short-Term; Muscarinic Antagonists; Neurons; Nicotinic Antagonists; Protein Biosynthesis; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine; TOR Serine-Threonine Kinases | 2013 |
Role of neuronal nicotinic acetylcholine receptors (nAChRs) on learning and memory in zebrafish.
Topics: Aconitine; Alkaloids; Animals; Azocines; Cholinergic Agents; Conotoxins; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Maze Learning; Mecamylamine; Memory; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Quinolizines; Receptors, Nicotinic; Scopolamine; Swimming; Zebrafish; Zebrafish Proteins | 2014 |
Differential effects of systemic cholinergic receptor blockade on Pavlovian incentive motivation and goal-directed action selection.
Topics: Animals; Anticipation, Psychological; Cholinergic Antagonists; Conditioning, Classical; Cues; Decision Making; Dietary Sucrose; Food Preferences; Goals; Male; Mecamylamine; Motivation; Motor Activity; Muscarinic Antagonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Reward; Scopolamine; Transfer, Psychology | 2014 |
Critical role of cholinergic transmission from the laterodorsal tegmental nucleus to the ventral tegmental area in cocaine-induced place preference.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Dopamine Uptake Inhibitors; Male; Mecamylamine; Muscarinic Antagonists; Neural Pathways; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Scopolamine; Space Perception; Tegmentum Mesencephali; Ventral Tegmental Area | 2014 |
Cholinergic inputs from Basal forebrain add an excitatory bias to odor coding in the olfactory bulb.
Topics: Action Potentials; Animals; Axons; Bacterial Proteins; Bias; Channelrhodopsins; Choline O-Acetyltransferase; Cholinergic Agents; Cholinergic Neurons; Female; Luminescent Proteins; Male; Mecamylamine; Mice; Mice, Transgenic; Odorants; Olfactory Bulb; Prosencephalon; Scopolamine; Smell | 2014 |
A new model to study visual attention in zebrafish.
Topics: Animals; Attention; Cholinergic Antagonists; Discrimination, Psychological; Female; Male; Mecamylamine; Memory; Motion; Neuropsychological Tests; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Photic Stimulation; Scopolamine; Visual Perception; Zebrafish | 2014 |
CDP-choline attenuates scopolamine induced disruption of prepulse inhibition in rats: involvement of central nicotinic mechanism.
Topics: Aconitine; Acoustic Stimulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Cytidine Diphosphate Choline; Male; Mecamylamine; Nicotinic Antagonists; Prepulse Inhibition; Rats, Sprague-Dawley; Reflex, Startle; Scopolamine | 2014 |
Influence of cholinesterase inhibitors, donepezil and rivastigmine on the acquisition, expression, and reinstatement of morphine-induced conditioned place preference in rats.
Topics: Animals; Cholinesterase Inhibitors; Conditioning, Psychological; Donepezil; Drug-Seeking Behavior; Indans; Male; Mecamylamine; Morphine; Motor Activity; Muscarinic Antagonists; Narcotics; Nicotinic Antagonists; Phenylcarbamates; Piperidines; Rats, Wistar; Rivastigmine; Scopolamine; Space Perception | 2014 |
A comparison of mecamylamine and bupropion effects on memory-related responses induced by nicotine and scopolamine in the novel object recognition test in mice.
Topics: Analysis of Variance; Animals; Bupropion; Cholinergic Agents; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Mecamylamine; Memory; Mice; Nicotine; Pattern Recognition, Visual; Scopolamine | 2014 |
Cholinergic receptor blockade by scopolamine and mecamylamine exacerbates global cerebral ischemia induced memory dysfunction in C57BL/6J mice.
Topics: Acetylcholinesterase; Animals; Brain Ischemia; Choline O-Acetyltransferase; Cholinergic Antagonists; Male; Mecamylamine; Memory Disorders; Mice; Mice, Inbred C57BL; Neurons; Receptors, Cholinergic; Reperfusion Injury; Scopolamine | 2014 |
Nicotine increases impulsivity and decreases willingness to exert cognitive effort despite improving attention in "slacker" rats: insights into cholinergic regulation of cost/benefit decision making.
Topics: Animals; Attention; Cholinergic Antagonists; Cognition; Decision Making; Impulsive Behavior; Male; Mecamylamine; Nicotine; Oxotremorine; Rats; Rats, Long-Evans; Reward; Scopolamine | 2014 |
Scopolamine and amphetamine produce similar decision-making deficits on a rat gambling task via independent pathways.
Topics: Amphetamine; Animals; Behavior, Animal; Choice Behavior; Decision Making; Gambling; Male; Mecamylamine; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Oxotremorine; Rats; Rats, Long-Evans; Reward; Scopolamine | 2015 |
Ventral tegmental area cholinergic mechanisms mediate behavioral responses in the forced swim test.
Topics: Acetylcholine; Animals; Cholinergic Antagonists; Cholinesterase Inhibitors; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Locomotion; Male; Mecamylamine; Neuropsychological Tests; Nicotinic Antagonists; Physostigmine; Rats, Sprague-Dawley; Scopolamine; Swimming; Ventral Tegmental Area | 2015 |
Muscarinic, but not nicotinic, acetylcholine receptor blockade in the ventral tegmental area attenuates cue-induced sucrose-seeking.
Topics: Animals; Appetitive Behavior; Cohort Studies; Conditioning, Operant; Cues; Dietary Sucrose; Dose-Response Relationship, Drug; Feeding Behavior; Male; Mecamylamine; Motivation; Muscarinic Antagonists; Neuropsychological Tests; Nicotinic Antagonists; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Nicotinic; Reward; Scopolamine; Self Administration; Ventral Tegmental Area | 2015 |
Distinct effects of ventral tegmental area NMDA and acetylcholine receptor blockade on conditioned reinforcement produced by food-associated cues.
Topics: Animals; Conditioning, Classical; Conditioning, Operant; Cues; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Mecamylamine; N-Methylaspartate; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Reinforcement, Psychology; Scopolamine; Valine; Ventral Tegmental Area | 2015 |
Muscarinic and nicotinic cholinergic receptor antagonists differentially mediate acquisition of fructose-conditioned flavor preference and quinine-conditioned flavor avoidance in rats.
Topics: Analgesics, Non-Narcotic; Animals; Avoidance Learning; Conditioning, Psychological; Fructose; Male; Mecamylamine; Muscarinic Antagonists; Nicotinic Antagonists; Quinine; Rats; Rats, Sprague-Dawley; Scopolamine; Sweetening Agents; Taste Perception | 2015 |
Cholinergic Modulation of Stimulus-Specific Adaptation in the Inferior Colliculus.
Topics: Acetylcholine; Acoustic Stimulation; Acoustics; Action Potentials; Adaptation, Physiological; Animals; Chi-Square Distribution; Cholinergic Agents; Cholinergic Antagonists; Female; Inferior Colliculi; Iontophoresis; Mecamylamine; Neurons; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Reaction Time; Scopolamine | 2015 |
Attenuation in rats of impairments of memory by scopolamine, a muscarinic receptor antagonist, by mecamylamine, a nicotinic receptor antagonist.
Topics: Acetylcholine; Animals; Cognition; Dose-Response Relationship, Drug; Hippocampus; Male; Mecamylamine; Memory Disorders; Memory, Short-Term; Muscarinic Antagonists; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Scopolamine; Spatial Memory | 2016 |
Acquisition and reinstatement of ethanol-induced conditioned place preference in rats: Effects of the cholinesterase inhibitors donepezil and rivastigmine.
Topics: Animals; Cholinesterase Inhibitors; Conditioning, Psychological; Donepezil; Ethanol; Indans; Male; Mecamylamine; Muscarinic Antagonists; Nicotinic Antagonists; Piperidines; Rats; Rats, Wistar; Receptors, Nicotinic; Reinforcement, Psychology; Rivastigmine; Scopolamine | 2016 |
Nucleus Accumbens Acetylcholine Receptors Modulate Dopamine and Motivation.
Topics: Animals; Cholinergic Antagonists; Conditioning, Classical; Conditioning, Operant; Cues; Dopamine; Electrochemical Techniques; Feeding Behavior; In Vitro Techniques; Male; Mecamylamine; Microelectrodes; Motivation; Nucleus Accumbens; Rats; Rats, Long-Evans; Receptors, Cholinergic; Reward; Scopolamine; Transfer, Psychology | 2016 |
Modulation of cue-triggered reward seeking by cholinergic signaling in the dorsomedial striatum.
Topics: Animals; Cholinergic Antagonists; Conditioning, Classical; Conditioning, Operant; Corpus Striatum; Cues; Male; Mecamylamine; Rats; Rats, Sprague-Dawley; Reward; Scopolamine | 2017 |
Rapamycin inhibits mTOR/p70S6K activation in CA3 region of the hippocampus of the rat and impairs long term memory.
Topics: Animals; Avoidance Learning; CA3 Region, Hippocampal; Male; Mecamylamine; Memory, Long-Term; Memory, Short-Term; Muscarinic Antagonists; Nicotinic Antagonists; Phosphorylation; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases, 70-kDa; Scopolamine; Sirolimus; TOR Serine-Threonine Kinases | 2017 |
The ventral hippocampal muscarinic cholinergic system plays a key role in sexual dimorphisms of spatial working memory in rats.
Topics: Animals; Drug Synergism; Female; Frontal Lobe; Hippocampus; Male; Maze Learning; Mecamylamine; Memory, Short-Term; Microinjections; Muscarinic Antagonists; Nicotinic Antagonists; Rats; Scopolamine; Sex Characteristics; Spatial Memory | 2017 |
Role of cholinergic receptors in memory retrieval depends on gender and age of memory.
Topics: Aging; Animals; Cholinergic Agents; Fear; Female; Male; Maze Learning; Mecamylamine; Memory, Short-Term; Mice, Inbred BALB C; Muscarinic Antagonists; Nicotinic Antagonists; Receptors, Cholinergic; Scopolamine; Sex Characteristics | 2017 |
Tone identification behavior in Rattus norvegicus: muscarinic receptor blockage lowers responsiveness in nontarget selective neurons, while nicotinic receptor blockage selectively lowers target responses.
Topics: Acoustic Stimulation; Action Potentials; Animals; Auditory Cortex; Auditory Perception; Brain Mapping; Conditioning, Operant; Male; Mecamylamine; Microelectrodes; Muscarinic Antagonists; Neurons; Nicotinic Antagonists; Pattern Recognition, Physiological; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine | 2017 |
Muscarinic acetylcholine receptor but not nicotinic acetylcholine receptor plays a role in morphine-induced behavioral sensitization in rats.
Topics: Alkaloids; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Locomotion; Male; Mecamylamine; Morphine; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine; Sesquiterpenes | 2017 |
Reduction in delay discounting due to nicotine and its attenuation by cholinergic antagonists in Lewis and Fischer 344 rats.
Topics: Animals; Delay Discounting; Male; Mecamylamine; Muscarinic Antagonists; Nicotine; Nicotinic Antagonists; Rats; Rats, Inbred F344; Rats, Inbred Lew; Scopolamine | 2018 |
Muscarinic and Nicotinic Contribution to Contrast Sensitivity of Macaque Area V1 Neurons.
Topics: Action Potentials; Animals; Contrast Sensitivity; Macaca mulatta; Male; Mecamylamine; Microelectrodes; Models, Neurological; Muscarinic Antagonists; Neurons; Neuropsychological Tests; Nicotinic Antagonists; Photic Stimulation; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine; Visual Cortex | 2017 |
Inhibitory modulation of the cough reflex by acetylcholine in the caudal nucleus tractus solitarii of the rabbit.
Topics: Acetylcholine; Animals; Antitussive Agents; Cholinergic Agonists; Cough; Male; Mecamylamine; Microinjections; Physostigmine; Rabbits; Receptors, Cholinergic; Reflex; Scopolamine; Solitary Nucleus | 2018 |
Intermittent stimulation in the nucleus basalis of meynert improves sustained attention in rhesus monkeys.
Topics: Animals; Attention; Basal Nucleus of Meynert; Central Nervous System Stimulants; Cholinesterase Inhibitors; Deep Brain Stimulation; Donepezil; Macaca mulatta; Male; Mecamylamine; Methylphenidate; Muscarinic Antagonists; Neural Pathways; Nicotinic Antagonists; Scopolamine | 2018 |
Effects of systemic cholinergic antagonism on reinforcer devaluation in macaques.
Topics: Acetylcholine; Animals; Cholinergic Antagonists; Conditioning, Operant; Discrimination Learning; Macaca mulatta; Male; Mecamylamine; Reinforcement, Psychology; Reward; Satiation; Scopolamine | 2018 |
Anti-cholinergics mecamylamine and scopolamine alleviate motion sickness-induced gastrointestinal symptoms through both peripheral and central actions.
Topics: Animals; Behavior, Animal; Cats; Cholinergic Antagonists; Hexamethonium; Hypothermia, Induced; Male; Mecamylamine; Models, Animal; Motion Sickness; Muscarinic Antagonists; Nausea; Neurons; Nicotinic Antagonists; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Scopolamine; Selenocysteine; Vomiting | 2019 |
Cholinergic Receptor Blockade in the VTA Attenuates Cue-Induced Cocaine-Seeking and Reverses the Anxiogenic Effects of Forced Abstinence.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Cholinergic Antagonists; Cocaine-Related Disorders; Disease Models, Animal; Drug-Seeking Behavior; Focal Adhesion Kinase 2; Male; Mecamylamine; Rats, Sprague-Dawley; Receptors, Cholinergic; Scopolamine; Ventral Tegmental Area | 2019 |
The effects and mechanisms of the action of galangin on spatial memory in rats.
Topics: Animals; Avoidance Learning; Cholinesterase Inhibitors; Donepezil; Flavonoids; Maze Learning; Mecamylamine; Rats; Rats, Sprague-Dawley; Reaction Time; Scopolamine; Spatial Memory | 2019 |
An acetylcholine-dopamine interaction in the nucleus accumbens and its involvement in ethanol's dopamine-releasing effect.
Topics: Acetylcholine; Animals; Cholinergic Antagonists; Dopamine; Ethanol; Male; Mecamylamine; Microdialysis; Nicotinic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Scopolamine; Ventral Tegmental Area | 2021 |
Cholinergic manipulations affect sensory responses but not attentional enhancement in macaque MT.
Topics: Acetylcholine; Animals; Attention; Cholinergic Agonists; Cholinergic Antagonists; Macaca mulatta; Male; Mecamylamine; Scopolamine; Visual Cortex; Visual Perception | 2021 |
Effects of nicotinic antagonists on working memory performance in young rhesus monkeys.
Topics: Aconitine; Animals; Conditioning, Operant; Dihydro-beta-Erythroidine; Female; Macaca mulatta; Male; Mecamylamine; Memory, Short-Term; Muscarinic Antagonists; Nicotinic Antagonists; Scopolamine | 2021 |